A system for denervation of nerves of a blood vessel

The system addresses the challenge of assessing denervation therapy efficacy by using impedance monitoring and linear scaling to provide real-time feedback, allowing for optimized treatment duration and effectiveness.

WO2025067860A1 Publication Date: 2025-04-03MEDTRONIC IRELAND MFG UNLIMITED CO
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Patent Information

Application Number
PCT/EP2024/075183
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-09-29
Filing Date
2024-09-10
Publication Date
2025-04-03

AI Technical Summary

Technical Problem

Current denervation procedures lack effective methods for assessing the progress and efficacy of the therapy, making it difficult for clinicians to determine the optimal duration and effectiveness of the treatment.

Method used

A system and method that involve applying nerve denervation therapy to a blood vessel wall, monitoring tissue impedance, calculating a linearly scaled impedance value, determining when this value exceeds a threshold, and ending the therapy, while also displaying an indication of therapy efficacy on a user interface.

Benefits of technology

This approach allows for real-time monitoring and feedback on the efficacy of the denervation therapy, enabling clinicians to adjust the treatment accordingly and ensuring that the therapy is completed effectively.

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Abstract

A system and method of performing a therapeutic procedure, including applying a nerve denervation therapy to a wall of a blood vessel, monitoring an impedance of tissue of the blood vessel, ending application of the therapy, and displaying on a user interface an indication of efficacy of the nerve denervation therapy.
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