Combined agents with synergistic effect against gliomas

WO2025125502A1PCT designated stage expired Publication Date: 2025-06-19EBERHARD KARLS UNIV TUBINGEN MEDIZINISCHE FAKULTAT
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Patent Information

Application Number
PCT/EP2024/086052
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-12-14
Filing Date
2024-12-12
Publication Date
2025-06-19

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Abstract

The present invention relates to a new pharmaceutical composition for the treatment and prophylaxis of a glioma comprising a first active agent combined with at least a second active agent, wherein the combination of said first and said second active agent results in a synergistic effect. The present invention also relates to a first active agent combined with at least a second active agent for use in the treatment and prophylaxis of a glioma wherein the combination of said first and said second active agent results in a synergistic effect. Finally, the invention relates to a method of treatment and prophylaxis of glioma in a subject in need, comprising the administration to the subject of said pharmaceutical composition or the combination of said first and said second active agent.
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Citation Information

Patent Citations

  • Use of dianhydrogalactitol or derivatives or analogs thereof for treatment of pediatric central nervous system malignancies

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  • Targeting the intrinsic apoptotic machinery in glioblastoma

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