Broad-spectrum peptoids for oral and dental hygiene, and compositions and methods of use thereof
Peptoid compounds MXB-22,510 and MXB-24,656 provide a broad-spectrum solution for treating oral and dental infections by offering antibacterial, antiviral, and antifungal properties, effectively addressing unidentified pathogens and biofilms, and promoting wound healing.
Patent Information
- Application Number
- PCT/US2025/016485
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-02-23
- Filing Date
- 2025-02-19
- Publication Date
- 2025-08-28
AI Technical Summary
There is a need for improved broad-spectrum treatments to prevent and treat oral and dental infections, particularly in environments where regular hygiene practices are not feasible, such as on the battlefield or in remote settings, and existing treatments are ineffective against unidentified pathogens or biofilms.
The use of peptoid compounds, specifically MXB-22,510 and MXB-24,656, which exhibit broad-spectrum antibacterial, antiviral, and antifungal properties, capable of disrupting biofilms and promoting wound healing, without requiring pathogen identification.
MXB-22,510 and MXB-24,656 demonstrate exceptional safety and efficacy against a wide range of pathogens, including multi-drug-resistant strains, and effectively prevent and treat infections in the oral cavity, lips, and dental infections, even in the absence of pathogen identification, with the ability to disrupt biofilms and promote healing.