Polyion complex and pharmaceutical composition

WO2025243932A1PCT designated stage Publication Date: 2025-11-27THE UNIV OF TOKYO
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Patent Information

Application Number
PCT/JP2025/017753
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-05-21
Filing Date
2025-05-15
Publication Date
2025-11-27

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Abstract

The present invention provides a polyion complex comprising: a block copolymer that has a hydrophilic polymer segment and a cationic poly(amino acid) segment; and a nucleic acid. The cationic poly(amino acid) segment includes an amino acid residue A that is selected from an amino acid residue having an achiral carbon atom as a carbon atom constituting the main chain and a polar non-charged amino acid residue, and also includes an amino acid residue B having a cationic group in a side chain.
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Citation Information

Patent Citations

  • Polynucleotide compositions for intramuscular and intradermal administration

    JP2002536399A

  • High molecular micelles including novel block copolymer

    WO2023149528A1