Non-naturally occurring melanocortin receptor agonists and use therefore in treatment of addiction and / or pain

WO2025245279A1PCT designated stage Publication Date: 2025-11-27ENDEVICA BIO INC
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Patent Information

Application Number
PCT/US2025/030447
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-10-24
Filing Date
2025-05-21
Publication Date
2025-11-27

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Abstract

Provided herein are methods of reducing or treating addiction and / or pain in a subject in need thereof, comprising administering to the subject a non-naturally occurring melanocortin analog. In some embodiments, the methods treat, prevent, or otherwise ameliorate an opioid use disorder (OUD) on an alcohol use disorder (AUD) in a subject in need thereof relative to a control.
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Citation Information

Patent Citations

  • Melanocortin analogs having enhanced activity and transport

    US20170081383A1

  • Method and system to predict response to pain treatments

    US20170247760A1

  • Melanocortin receptor ligands

    US20220127305A1

  • Methods of preventing and / or treating side effects associated with Anti-cancer agents using non-naturally occurring melanocortin analogs with Anti-GDF-15 antibodies

    WO2024173905A1