Trop2-binding molecules
WO2026019374A1PCT designated stage Publication Date: 2026-01-22HUMMINGBIRD BIOSCIENCE HOLDINGS PTE LTD
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Patent Information
- Application Number
- PCT/SG2025/050488
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-07-19
- Filing Date
- 2025-07-18
- Publication Date
- 2026-01-22
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Figure SG2025050488_22012026_PF_FP_ABST
Abstract
Provided here are antigen-binding molecules that bind to TROP2, comprising (i) a TROP2-binding moiety, and (ii) at least one linker-payload moiety, wherein the antigen-binding molecule comprises (a) a DNA damage response (DDR) inhibitor moiety, and (b) a DNA topoisomerase I (TOP1) inhibitor moiety.
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Citation Information
Patent Citations
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