Biomedical scaffold, preparation method therefor, use method therefor, and use thereof
WO2026060559A1PCT designated stage Publication Date: 2026-03-26SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-09-18
- Publication Date
- 2026-03-26
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Figure CN2024119366_26032026_PF_FP_ABST
Abstract
The present invention provides a biomedical scaffold, a preparation method therefor, a use method therefor, and use thereof. The biomedical scaffold comprises the following starting material components in percentage by mass: 96.0%-99.5% of shape memory polyurethane and 0.5%-4% of active particles, wherein the active particles comprise one or more of manganese dioxide, nano magnesium oxide, ferroferric oxide, and magnesium metal. According to the present invention, by means of utilizing the easy volatility of dichloromethane, the pressure in a container is increased, thereby enabling homogeneous dissolution of shape memory polyurethane and uniform dispersion and mixing of active ingredients. By means of room-temperature volatilization and deposition, such shape memory materials are 3D printed, and the printed structures, such as pore size and porosity, are further designed to achieve good shape memory performance and mechanical properties. In addition, a plurality of scaffolds can be heated in various ways, such as near-infrared light irradiation and hot water soaking. Thus, the scaffolds can be assembled into a specific shape and exhibit strong stability and mechanical properties.
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