Microfluidic preparation method for adiposome delivery platform
WO2026092305A8PCT designated stage Publication Date: 2026-07-09WECARELIFE BIOTECH CO LTD
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- WECARELIFE BIOTECH CO LTD
- Filing Date
- 2025-10-24
- Publication Date
- 2026-07-09
AI Technical Summary
Technical Problem
Existing technologies for preparing fat bodies suffer from low phospholipid utilization, low production efficiency, and are unsuitable for large-scale production.
Method used
Using microfluidic chip technology, lipid and aqueous solutions are rapidly mixed in a microfluidic chip to form a fat body delivery platform. The molar ratio of polar to non-polar lipids is optimized, and high-purity fat bodies with uniform particle size are obtained by ultrafiltration concentration.
Benefits of technology
It significantly improves the utilization rate of fat body raw materials, and realizes the efficient preparation of high-purity fat bodies with uniform particle size, which is suitable for industrial production.
✦ Generated by Eureka AI based on patent content.
Abstract
The present invention provides a microfluidic preparation method for an adiposome delivery platform, comprising the following steps: S1) providing a lipid solution and an aqueous phase solution, wherein the lipid solution comprises a polar lipid and a non-polar lipid, and the molar ratio of the polar lipid to the non-polar lipid is 1:(0.5-6); and S2) introducing each of the lipid solution and the aqueous phase solution into a microfluidic chip to obtain an adiposome delivery platform. Compared with the prior art, the present invention relates to rapidly mixing the lipid solution and the aqueous phase solution in a channel of the microfluidic chip to form the adiposome delivery platform, which significantly improves the utilization rate of adiposome raw materials, can achieve rapid and efficient preparation of adiposomes having high purity and a uniform particle size, and can also achieve loading of fat-soluble small-molecule drugs, thereby paving the way for industrial production of the adiposome delivery platform.
Need to check novelty before this filing date? Find Prior Art