Probiotic composition and postbiotic thereof, preparation method therefor, and use thereof
By using a probiotic composition with a specific ratio and postbiotics prepared by ultrasonic lysis, the problem of poor regulation of the microbial community and the susceptibility of its activity to environmental influences in existing oral health management methods has been solved, achieving the effect of effectively inhibiting oral pathogens and maintaining microbial balance.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- BGI PRECISION NUTRITION (SHENZHEN) TECHNOLOGY CO LTD
- Filing Date
- 2024-11-18
- Publication Date
- 2026-05-21
AI Technical Summary
Existing oral health management methods cannot effectively regulate oral flora, resulting in problems such as excessive acid production, susceptibility to oral environment influences, and significant side effects. Furthermore, existing probiotics are easily affected by temperature and humidity, making it difficult to maintain their activity in products.
A probiotic composition was prepared by fermentation using a specific ratio of Lactobacillus rhamnosus OF44-15Ph10T, Lactobacillus reuteri BGI-AM60, and Lactobacillus plantarum BGI-N6. The composition was then subjected to ultrasonic lysis to prepare postbiotics, which maintained the antibacterial effect.
This probiotic composition and postbiotic can effectively inhibit oral pathogens, reduce lactic acid production, reduce tooth erosion, maintain oral microbiome balance, and remain active under different environments, thus reducing side effects.
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Figure CN2024132700_21052026_PF_FP_ABST