Probiotic composition and postbiotic thereof, preparation method therefor, and use thereof

By using a probiotic composition with a specific ratio and postbiotics prepared by ultrasonic lysis, the problem of poor regulation of the microbial community and the susceptibility of its activity to environmental influences in existing oral health management methods has been solved, achieving the effect of effectively inhibiting oral pathogens and maintaining microbial balance.

WO2026102769A1PCT designated stage Publication Date: 2026-05-21BGI PRECISION NUTRITION (SHENZHEN) TECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
BGI PRECISION NUTRITION (SHENZHEN) TECHNOLOGY CO LTD
Filing Date
2024-11-18
Publication Date
2026-05-21

AI Technical Summary

Technical Problem

Existing oral health management methods cannot effectively regulate oral flora, resulting in problems such as excessive acid production, susceptibility to oral environment influences, and significant side effects. Furthermore, existing probiotics are easily affected by temperature and humidity, making it difficult to maintain their activity in products.

Method used

A probiotic composition was prepared by fermentation using a specific ratio of Lactobacillus rhamnosus OF44-15Ph10T, Lactobacillus reuteri BGI-AM60, and Lactobacillus plantarum BGI-N6. The composition was then subjected to ultrasonic lysis to prepare postbiotics, which maintained the antibacterial effect.

Benefits of technology

This probiotic composition and postbiotic can effectively inhibit oral pathogens, reduce lactic acid production, reduce tooth erosion, maintain oral microbiome balance, and remain active under different environments, thus reducing side effects.

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Abstract

The present invention provides a probiotic composition and a postbiotic thereof, a preparation method therefor, and use thereof. The probiotic composition is obtained by inoculating Lactobacillus rhamnosus OF44-15Ph10T, Lactobacillus reuteri BGI-AM60, and Lactiplantibacillus plantarum BGI-N6 in a certain ratio and then culturing same.
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