Compound and use thereof
By combining compound I with acid suppressants and antibiotics, the problems of drug resistance and biofilm protection in Helicobacter pylori infection have been solved, achieving a highly effective eradication and low recurrence rate. It is suitable for Helicobacter pylori infection in various digestive tract sites.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- TENNOR THERAPEUTICS (SUZHOU) LTD
- Filing Date
- 2025-11-14
- Publication Date
- 2026-05-21
AI Technical Summary
Existing drugs for treating Helicobacter pylori infection have problems such as high drug resistance, difficulty in killing bacteria in a low metabolic state, and difficulty in eradicating bacteria under biofilm protection, resulting in low eradication rate and high recurrence rate.
A compound or a composition thereof, comprising a compound of formula I, is provided for use in combination with an acid suppressant and an antibiotic to directly kill susceptible and low-metabolic Helicobacter pylori, disrupt biofilms, improve eradication rates, and reduce recurrence rates.
Compound I has high bactericidal efficiency against susceptible bacteria, shortens the course of treatment, improves patient compliance, significantly increases the eradication rate and reduces the recurrence rate, and is suitable for infections in various parts of the digestive tract.
Smart Images
Figure CN2025134891_21052026_PF_FP_ABST