Chlorophyll derivatives, carotenoid derivatives, and dietary supplements for human ocular health and visual performance

A composition of chlorophyll and carotenoid derivatives, along with dietary supplements, addresses the need for enhanced visual performance and ocular health by improving mitochondrial function and reducing inflammation, effectively treating age-related macular degeneration.

WO2026106725A1PCT designated stage Publication Date: 2026-05-21RETINABIO INC
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
RETINABIO INC
Filing Date
2025-09-29
Publication Date
2026-05-21

AI Technical Summary

Technical Problem

Current dietary supplements for eye health primarily focus on slowing the progression of age-related diseases but lack formulations that enhance visual performance and support ocular cell metabolism and longevity, especially for aging individuals with or without retinal diseases like AMD.

Method used

A composition comprising chlorophyll derivatives, carotenoid derivatives, and dietary supplements, including vitamins and antioxidants, formulated to improve ocular health and visual performance, administered via various routes to enhance mitochondrial function, reduce inflammation, and support cellular longevity.

Benefits of technology

The composition effectively improves visual performance by enhancing contrast sensitivity, low luminance visual acuity, and reduces the progression of age-related macular degeneration, while supporting ocular cell metabolism and longevity.

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Abstract

Disclosed herein are compositions, methods, and uses of compositions for eye health and visual performance. Compositions may include the utilization of chlorophyll derivatives with or without nicotinamide derivatives, carotenoid derivatives, and dietary supplements. Further, the disclosure provides that chlorophyll may increase adenosine triphosphate (ATP) production and coupling efficiency in human retinal pigment epithelial (hRPE) cells. The disclosure also illustrates that chlorophyll and nicotinamide together increase ATP production and basal oxygen consumption rate in hRPE cells.
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