Drug eluting balloon with radial projections

The balloon catheter device with radially projecting portions and restrained areas addresses the limitations of full vessel blockage by enhancing drug absorption and reducing clotting risk through partial blood flow and drug pooling.

WO2026107150A1PCT designated stage Publication Date: 2026-05-21TERUMO MEDICAL CORP
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
TERUMO MEDICAL CORP
Filing Date
2025-11-13
Publication Date
2026-05-21

AI Technical Summary

Technical Problem

Existing drug-eluting balloon catheters fully block blood vessels during treatment, limiting drug absorption time and increasing the risk of clotting due to blocked blood flow.

Method used

A balloon catheter device with radially projecting portions and restrained areas that form channels, allowing drug pooling against the vessel wall while maintaining partial blood flow, and optionally combined with a blood-flow barrier to enhance drug delivery duration.

Benefits of technology

Enhances drug absorption by prolonging treatment duration and reducing the risk of clotting by allowing partial blood flow and minimizing drug waste.

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Abstract

A balloon catheter device (100) includes a catheter (104) and a balloon assembly. The catheter defines a guidewire lumen and a drug lumen (108). The balloon assembly includes a balloon (110) coupled to an outer surface of the catheter, a proximal retainer coupled to the catheter at a proximal end of the balloon, a distal retainer coupled to the catheter at a distal end of the balloon, and a plurality of restraints (332) coupled between the proximal and the distal retainer. The balloon is configured to receive a drug from the drug lumen (106). When the balloon is in an expanded state, the balloon has a plurality of restrained portions, each extending along a length of one of the restraints, and a plurality of radially projecting portions, each positioned between adjacent of the restrained portions. The radially projecting portions extend further radially outward from the catheter than the restrained portions.
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