Modular diagnostic assay
The modular diagnostic assay system addresses the challenge of inadequate diagnostic infrastructure in limited resource settings by providing a manually operated, electricity-free system for rapid and sensitive diagnosis of infectious diseases, achieving high sensitivity and specificity.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- CHROMOLOGIC LLC
- Filing Date
- 2025-11-17
- Publication Date
- 2026-05-21
AI Technical Summary
The infrastructure for rapid and precise diagnostic testing of infectious diseases, particularly in limited resource settings, is inadequate, posing challenges for timely diagnosis of diseases like malaria and other neglected tropical diseases.
A modular diagnostic assay system that includes a fluidic subsystem, molecular biology subsystem, and heating subsystem, utilizing a manually operated fluidic device with check valves, isothermal nucleic acid amplification, and CRISPR recognition, enabling self-administered diagnosis without electricity, with a visual readout.
The system achieves rapid and sensitive diagnosis of infectious diseases, reaching a sensitivity of 10 parasites/pL within 1 hour, suitable for point-of-care testing in remote areas, and is scalable for various diseases.
Smart Images
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