Nucleic acid-encapsulating lipid nanoparticle, nucleic acid vaccine, cell production method, and cell production kit
WO2026115768A1PCT designated stage Publication Date: 2026-06-04NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY
- Filing Date
- 2025-05-15
- Publication Date
- 2026-06-04
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Figure JP2025017632_04062026_PF_FP_ABST
Abstract
A nucleic acid-encapsulating lipid nanoparticle according to the present invention comprises: a lipid membrane structure having, as constituent components, a lipid bonded to poly(2-methacryloyloxyethyl phosphorylcholine), a cationic lipid, a non-cationic lipid, and a sterol; and a nucleic acid included in the lipid membrane structure. The molar ratio of the cationic lipid in the lipid membrane structure is 20-80%.
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