Nucleic acid-encapsulating lipid nanoparticle, nucleic acid vaccine, cell production method, and cell production kit

WO2026115768A1PCT designated stage Publication Date: 2026-06-04NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY
Filing Date
2025-05-15
Publication Date
2026-06-04

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Abstract

A nucleic acid-encapsulating lipid nanoparticle according to the present invention comprises: a lipid membrane structure having, as constituent components, a lipid bonded to poly(2-methacryloyloxyethyl phosphorylcholine), a cationic lipid, a non-cationic lipid, and a sterol; and a nucleic acid included in the lipid membrane structure. The molar ratio of the cationic lipid in the lipid membrane structure is 20-80%.
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