Ablation system

The ablation system employs irreversible electroporation with monopolar and bipolar voltage applications to address thermal damage issues in RF ablation, achieving targeted tissue lesions with reduced collateral damage.

WO2026120894A1 Publication Date: 2026-06-11JAPAN LIFELINE CO LTD
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Patent Information

Application Number
PCT/JP2025/033750
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-12-05
Filing Date
2025-09-25
Publication Date
2026-06-11

AI Technical Summary

Technical Problem

Existing ablation technologies using radio frequency (RF) energy often cause thermal damage to surrounding tissues and nerves, leading to complications such as esophageal fistula and phrenic nerve paralysis during cardiac procedures.

Method used

An ablation system utilizing irreversible electroporation (IRE) with a surgical device featuring a clip portion and ablation electrodes, capable of monopolar and bipolar voltage applications, to perform pulsed electric field ablation (PFA) that minimizes thermal damage by using high-voltage pulses to create lesions in tissue without heat.

Benefits of technology

The IRE-based ablation system effectively forms targeted lesions while reducing damage to adjacent tissues and nerves, thereby minimizing complications like esophageal fistula and phrenic nerve paralysis.

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Abstract

An ablation system 1 for performing ablation of biological tissue 2 using an irreversible electroporation method comprises: a surgical treatment tool 4 having a shaft 10, a clip part 12 including a pair of holding pieces 16 and at least one ablation electrode provided on at least one of the holding pieces 16, and an operation part 22 that opens and closes the clip part 12; a counter electrode plate 6; a power supply part 26 that applies a voltage to the at least one ablation electrode 18 and the counter electrode plate 6; and a control part 28 that controls the power supply part 26 so as to execute monopolar system application that applies the voltage between the at least one ablation electrode 18 and the counter electrode plate 6.
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