Flexible nanoelectrode systems and methods

Flexible nanoelectrode systems address the challenge of combining robustness and flexibility in neural electronics, offering stable long-term neural recording and stimulation, enhancing therapeutic efficacy for neurological disorders.

WO2026122607A1PCT designated stage Publication Date: 2026-06-11PRESIDENT & FELLOWS OF HARVARD COLLEGE

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
PRESIDENT & FELLOWS OF HARVARD COLLEGE
Filing Date
2025-12-03
Publication Date
2026-06-11

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Abstract

The present disclosure generally relates to nanoscale or microscale wires and nanoelectronics or microelectronics, and to systems and methods for implanting such devices into an organ of a subject, such as the brain, heart, etc. The devices may include soft and / or mechanically flexible portions in some cases. In some embodiments, such devices may include a plurality of electrodes, e.g., in a mesh or an array. In some cases, the devices may be configured to determine electrical signals at mesoscale resolutions, which may allow for determination and / or stimulation of electrical signals within the organ. Some embodiments may allow for closed-loop stimulation at mesoscale resolutions, e.g., across multiple targets, and / or by targeting specific subregions of an organ. Other aspects are generally directed to systems and methods for making or using such devices, kits involving such devices, or the like.
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