Crystalline forms and methods of synthesis

WO2026131688A2PCT designated stage Publication Date: 2026-06-25ASTRAZENECA AB
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
ASTRAZENECA AB
Filing Date
2025-12-15
Publication Date
2026-06-25

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Abstract

Crystalline 6'-([(1S,3S)-3-([5-(difluoromethoxy)-2-pyrimidinyl]amino)cyclopentyl]amino)-2H- [1,3'-bipyridin]-2-one (AZD0780) in form B, a crystalline form comprising AZD0780 and fumaric acid as a co-crystal, a crystalline form comprising AZD0780 and succinic acid as a co-crystal, and a method of making AZD0780 with key intermediates.
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