Periodontal tissue regeneration-inducing material comprising acellular dermal matrix and method for preparing same

Acellular allogeneic dermis-based periodontal tissue regeneration material addresses the limitations of heterologous collagen by ensuring biocompatibility and stability without cross-linking, enhancing tissue regeneration efficacy.

WO2026141969A1PCT designated stage Publication Date: 2026-07-02L&C BIO CO LTD

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
L&C BIO CO LTD
Filing Date
2025-11-14
Publication Date
2026-07-02

AI Technical Summary

Technical Problem

Existing periodontal tissue regeneration-inducing materials using heterologous collagen face issues with immune responses, rapid degradation, and side effects due to chemical cross-linking processes, necessitating a more stable and biocompatible alternative.

Method used

A periodontal tissue regeneration-inducing material composed of acellular allogeneic dermis, which includes collagen and extracellular matrix, is manufactured without a cross-linking process, ensuring high shape retention and degradation resistance through a freeze-drying method.

Benefits of technology

The material provides safe and effective tissue regeneration by minimizing material degradation and side effects, promoting rapid blood penetration and nutrient supply, while maintaining structural integrity.

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Abstract

The present invention relates to a periodontal tissue regeneration-inducing material comprising acellular dermal matrix (ADM) and a method for preparing same. The periodontal tissue regeneration-inducing material according to the present invention can be prepared without undergoing a crosslinking process, by using ADM, thereby minimizing the denaturation of raw materials occurring in the crosslinking process. In addition, the ADM contains not only collagen but also an extracellular matrix, thereby providing degradation resistance and high shape retention.
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