Nisin for ethanol microbial control and cleaning

Nisin, used as a sole antimicrobial in ethanol production systems, addresses microbial contamination by enhancing production efficiency and ensuring safe by-product streams, overcoming antibiotic resistance concerns and waste disposal constraints.

WO2026147750A1PCT designated stage Publication Date: 2026-07-09ECOLAB USA INC
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
ECOLAB USA INC
Filing Date
2025-12-19
Publication Date
2026-07-09

AI Technical Summary

Technical Problem

Microbial contamination in ethanol fermentation systems leads to reduced ethanol yields, production inefficiencies, and the accumulation of organic residues and biofilms, posing challenges due to the limitations of conventional antibiotics and strict waste disposal standards.

Method used

The use of nisin, a bacteriocin, as the sole antimicrobial agent in ethanol production systems, combined with surfactants, to control microbial populations and enhance cleaning and sanitization, thereby increasing ethanol production rates and reducing production time.

Benefits of technology

Nisin effectively reduces microbial populations, enhances ethanol production efficiency, and ensures the production of safe by-products by minimizing antibiotic residues and maintaining compliance with waste disposal regulations.

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Abstract

Compositions, methods, and systems for controlling microbial populations within an ethanol production system. Nisin and other components may be applied to various parts of an ethanol production system, such as of a mash cooler, a mash tank, a fermentation tank, a fermentation cooler, a drain, a yeast propagation tank, a liquefaction tank, a slurry tank, a strainer, a jet cooker, a hammer mill, a beerwell, a backset, a heat exchanger, a urea tank, a premix tank, or combinations thereof.
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