Wire-based oxygenator and applications thereof

The wire-based oxygenation system addresses the challenge of limited oxygen supply in high cell density biomedical devices by using customizable catalyst-coated electrodes for efficient oxygen generation, improving cell viability and functionality.

WO2026148243A1PCT designated stage Publication Date: 2026-07-09NORTHWESTERN UNIV +1

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
NORTHWESTERN UNIV
Filing Date
2026-01-05
Publication Date
2026-07-09

AI Technical Summary

Technical Problem

Existing methods for supporting high cell densities in biomedical devices suffer from limited oxygen supply and poor diffusivity, leading to decreased cell viability away from the oxygen source.

Method used

A wire-based oxygenation system with customizable geometry and catalyst-coated electrodes, including working and counter electrodes, which utilize electrocatalytic oxygen evolution reaction to generate oxygen efficiently and sustainably for implanted cells.

Benefits of technology

The system provides stable and abundant oxygen supply, enhancing cell viability and functionality by maintaining efficient oxygen distribution and reducing power consumption.

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Abstract

An ‎oxygenation system producing oxygen for therapeutic cells housed in an implanted or ‎external system comprises an insulating scaffold; a working electrode (WE) disposed in association with the insulating scaffold; a counter electrode (CE) disposed in association with the insulating scaffold; wherein the working electrode comprises at least one catalyst for electrocatalytic oxygen evolution reaction ‎‎(OER).‎
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