Pneumatic growth-based soft nasal swab and sampling method

Abstract

A pneumatic growth-based soft nasal swab and a sampling method. The soft nasal swab comprises an axial drive section (4), an auxiliary support surface section (3), an intermediate folding surface section (2), and a front-end brush section (1) which are sequentially connected from back to front. The inflation deformation of different sections is achieved by means of the axial drive section (4), so as to adapt to the movement of the nasal swab in a sampling direction in the nasal cavity; the transmission of force during the use of the nasal swab is controlled by means of the auxiliary support surface section (3); automatic folding and rotation are achieved by means of the intermediate folding surface section (2); the sampling accuracy is improved by means of the front-end brush section (1), and automatic sampling is also achieved. By means of the specific sampling method steps, cross-infection is reduced. By means of gas pressure driving and the structural design of different parts of the nasal swab, a driving source is simplified, reducing the safety risk.

Description

A soft body nasal swab based on pneumatic growth and a sampling method TECHNICAL FIELD

[0001] The present application relates to the field of medical devices, and more particularly, to a soft body nasal swab based on pneumatic growth and a sampling method. BACKGROUND

[0002] A nasal swab is a small tool used to pick up substances on the inner wall of the nasal cavity, which will be used for detection or experiments.

[0003] The existing nasal swab is mainly a small wooden stick with a cotton swab at one end, and the end of the cotton swab is used for sampling. During the operation, the doctor usually holds the small wooden stick with the smooth end, sends the cotton swab into the deep part of the nostril and rotates it, so as to pick up the liquid or solid substances on the inner wall of the nasal cavity and take them out. The nasal swab of this structure has high hardness and lacks flexibility, which can easily hurt the inner wall of the nasal cavity, and the subject will experience great pain during the sampling process. At the same time, the medical staff and the subject need to be in contact during sampling, which may cause cross infection. TECHNICAL PROBLEM

[0004] How to improve the experience of the subject and realize automatic sampling to avoid cross infection between the medical staff and the subject is a problem to be solved in the field. TECHNICAL SOLUTION

[0005] The present application aims to overcome at least one of the above-mentioned defects (shortcomings) of the prior art, and provides a soft body nasal swab based on pneumatic growth and a sampling method, which is used to solve the problems that the existing nasal swab lacks flexibility, is easy to hurt the inner wall of the nasal cavity of the subject, and causes poor sampling experience; the medical staff and the subject are directly in contact, which may cause cross infection risk, and automatic sampling cannot be realized.

[0006] The technical scheme adopted by the present application is to provide a soft body nasal swab based on pneumatic growth, which comprises an axial driving section, an auxiliary support surface section, an intermediate folding surface section and a front end brush section connected in sequence from back to front, the nasal swab is in a hollow state, the axial driving section is used to control the filling of gas in the cavity and the sampling power of the nasal swab, the auxiliary support surface section is used to transmit the driving force of the axial driving section to the front end brush section, the intermediate folding surface section is used to provide auxiliary driving force and buffer for the pressure received by the front end brush section, and the front end brush section is used to collect samples in the nasal cavity.

[0007] It is beneficial to deform other different segments in the nasal swab by the axial driving segment to adapt to the movement of the sampling direction in the nasal cavity; to provide support force through the auxiliary support surface segment to control the force transmission of the nasal swab during use; to realize automatic folding and rotation of the nasal swab through the intermediate folding surface segment to avoid poking the nasal cavity and improve the experience of the subject; to realize automatic large-area rotation sampling in the nasal cavity through the front-end brush segment, improve the sampling accuracy, and avoid direct contact between medical personnel and the subject to realize automatic sampling.

[0008] Further, the front-end brush segment is a spherical cavity, a plurality of brushes are uniformly arranged on the surface of the spherical cavity, the bottom of the spherical cavity is connected to the intermediate folding surface segment, and the top of the spherical cavity is a smooth plane.

[0009] It is beneficial to increase the contact area between the nasal swab and the inner wall of the nasal cavity by arranging a plurality of brushes on the surface, thereby increasing the sample collection concentration; the front-end brush segment is connected to the intermediate folding surface segment to realize rotary sampling, shorten the sampling time, and improve the sampling efficiency; the resistance received in the nasal cavity is transmitted to the intermediate folding surface segment along the axial direction through the smooth plane.

[0010] Further, the intermediate folding surface segment is a foldable cavity, the foldable cavity includes a plurality of circular rings, the diameter of each circular ring decreases in the axial direction from back to front, and when the intermediate folding surface segment is extruded by the front-end brush segment, the plurality of circular rings are extruded and shrink in the axial direction from front to back.

[0011] It is beneficial to couple the sampling rotation and the front-end pressure together through the intermediate folding surface segment to realize elastic sampling of the nasal swab and improve the experience of the subject; the plurality of circular rings realize the telescopic folding of the intermediate folding surface segment in the axial direction.

[0012] Further, each circular ring includes a plurality of diamond surfaces, the plurality of diamond surfaces are spliced to form a circular ring in the circumferential direction, the diamond surfaces on each circular ring convert the axial force into the tangential force when the intermediate folding surface segment is extruded by the front-end brush segment, and the plurality of circular rings rotate and fold in the circumferential direction.

[0013] It is beneficial to convert the axial force into the tangential force through the splicing of the plurality of diamond surfaces of each circular ring, thereby realizing the automatic rotation of the front-end brush segment.

[0014] Further, the auxiliary support surface segment is a cylindrical cavity, the top of the cylindrical cavity is connected to the bottom of the intermediate folding surface segment, the bottom of the cylindrical cavity is connected to the top of the axial driving segment, the axial length of the auxiliary support surface segment is H3, the axial length of the intermediate folding surface segment is H2, the axial length of the front-end brush segment is H1, and H3>H1+H2.

[0015] The axial length of the auxiliary support surface section is greater than the sum of the axial lengths of the intermediate folding surface section and the front end brush section, so that the auxiliary support surface section can provide sufficient support in the axial direction to prevent the force conducted downward along the axial direction of the intermediate folding surface section.

[0016] Further, the axial driving section is in the shape of a drum cavity, which includes a top drum surface and a bottom drum surface with the same diameter, and the bottom drum surface is connected to the pressurizing device through the air pipe. After being pressurized by the pressurizing device, the axial driving section expands in the axial direction and pushes the front end brush section to advance.

[0017] The pressurizing device provides inflation power, the axial driving section provides large-area base support for the auxiliary support surface section, and at the same time provides a buffer space for the inflation of the nasal swab, so that the inflation deformation of each section of the nasal swab can be completed in coordination to complete the sampling task.

[0018] Further, the diameter of the top drum surface is D4, the diameter of the auxiliary support surface section is D3, the diameter of the bottom of the intermediate folding surface section is D22, the diameter of the top of the intermediate folding surface section is D21, the diameter of the brush formed on the outer edge of the front end brush section is D1, and the diameter of the air pipe is D5. D4>D1>D3=D22>D21>D5.

[0019] The different diameters of each section of the nasal swab make the soft nasal swab realize different actions in each section to adapt to the deformation of the internal environment of the nasal cavity, the small diameter of the air pipe increases the inflation airflow speed, the diameter of the intermediate folding surface section gradually decreases from the bottom to the top to realize axial telescoping, the diameter of the brush outer edge is greater than that of the intermediate folding surface section to increase the sampling contact area, and the diameters of the auxiliary support surface section and the bottom of the intermediate folding surface section are the same to improve the transmission efficiency of the pressure in the axial direction.

[0020] Also provided is a soft nasal swab sampling method based on pneumatic growth, wherein, according to the soft nasal swab, the method comprises the following steps:

[0021] S1. The subject remains stationary, replaces the soft nasal swab, fixes it, and places the nasal swab close to the lower part of the nostril of the subject through a mechanical arm;

[0022] S2. Start the pressurizing device to inflate the soft nasal swab, and after the axial driving section, the auxiliary support surface section, the intermediate folding surface section, and the front end brush section of the nasal swab expand in turn, the front end brush section extends into the nasal cavity to prepare for sampling;

[0023] S3. When the front end brush section is blocked at the sampling position in the nasal cavity, the intermediate folding surface section transmits the resistance to make the intermediate folding surface section telescope downward while rotating in the circumferential direction.

[0024] S4. The front brush segment connected to the intermediate folded surface segment is driven to rotate, thereby realizing the collection of biological samples inside the nasal cavity;

[0025] S5. After the nasal swab is collected, the robotic arm places the front brush section into the collection box, turns off the pressurization device, removes the soft nasal swab, and prepares for the next sampling.

[0026] This method helps avoid contact between medical staff and subjects during the sampling process, reducing cross-infection; the gas pressure drive and the structural design of different parts of the nasal swab allow a single drive source to complete different actions at different stages, making the operation simple; the soft material of the soft nasal swab reduces safety risks, and the deformation of the soft material adapts to changes in the nasal cavity environment, resulting in better sampling coverage.

[0027] Step S2 specifically includes:

[0028] S21. After the axial drive section is inflated, the gas quickly enters the front brush section through the cylindrical cavity, and the front brush section extends into the nasal cavity;

[0029] S22. The axial drive section and the auxiliary support section provide support for the intermediate folded section. After continuous inflation, each layer of rings in the intermediate folded section is fully unfolded.

[0030] S23. As the front brush segment gradually penetrates deeper, the forward resistance gradually increases. When it reaches the sampling position inside the nasal cavity, the squeezing resistance of the front brush segment is the greatest, and this resistance is transmitted to the middle folded surface segment.

[0031] It is beneficial to achieve elastic sampling of nasal swabs by observing the specific movement changes of the axial drive section, auxiliary support surface section and front brush section during inflation.

[0032] Step S3 specifically includes:

[0033] S31. The top of the front brush section is a smooth plane. When it reaches the sampling position inside the nasal cavity, it encounters the greatest resistance. The smooth plane transmits the resistance axially to the top of the middle folded section.

[0034] S32. The top of the intermediate folded surface segment transmits a portion of the resistance along the axial direction on its multi-layered rings to the bottom of the intermediate folded surface segment, and the multi-layered rings overlap along the axial direction under the action of this portion of resistance;

[0035] S33. The top of the intermediate folded surface segment transmits another part of the resistance in the rhomboid surface of each ring along the tangential direction. Since the bottom of the intermediate folded surface segment is connected to the auxiliary support surface segment, the auxiliary support surface segment provides support for the bottom of the intermediate folded surface segment and prevents this part of the resistance from continuing to be transmitted along the axial direction, so that the intermediate folded surface segment rotates along the tangential circumferential direction under the action of this part of the resistance.

[0036] It is beneficial to achieve large-area rotational sampling by observing the stress state and specific action changes of the intermediate folded surface segment at each stage. Beneficial effects

[0037] Compared with existing technologies, the beneficial effects of this invention are as follows: The axial drive section inflates and deforms other different segments of the nasal swab to adapt to movement in the sampling direction within the nasal cavity; the auxiliary support surface section provides support to control the force transmission during use; the intermediate folding section enables automatic folding and rotation of the nasal swab to avoid puncturing the nasal cavity and improve the subject's experience; the front brush section automatically rotates and samples over a large area within the nasal cavity, improving sampling accuracy while avoiding direct contact between medical personnel and subjects, thus achieving automated sampling; the specific sampling method steps avoid contact between medical personnel and subjects during sampling, reducing cross-infection; the gas pressure drive and structural design of different parts of the nasal swab allow a single drive source to complete different actions at different stages, simplifying operation; the soft material of the soft nasal swab reduces safety risks, and the deformation of the soft material adapts to changes in the nasal cavity environment, resulting in better sampling coverage. Attached Figure Description

[0038] Figure 1 is an overall structural diagram of the present invention.

[0039] Figure 2 is a schematic diagram of the expanded state of the soft nasal swab of the present invention.

[0040] Figure 3 is a schematic diagram of the contracted state of the soft nasal swab of the present invention.

[0041] Explanation of the symbols in the attached diagram: 1. Front brush section, 2. Middle folded surface section, 3. Auxiliary support surface section, 4. Axial drive section. Embodiments of the present invention

[0042] The accompanying drawings are for illustrative purposes only and should not be construed as limiting the invention. To better illustrate the following embodiments, some parts in the drawings may be omitted, enlarged, or reduced, and do not represent the actual product dimensions; it is understandable to those skilled in the art that some well-known structures and their descriptions may be omitted in the drawings. Example

[0043] As shown in Figures 1-3, this embodiment provides a soft nasal swab based on pneumatic growth, which includes an axial drive section 4, an auxiliary support surface section 3, an intermediate folded surface section 2, and a front brush section 1 connected sequentially from back to front. The nasal swab is cavity-shaped. The axial drive section 4 is used to control the gas filling in the cavity and the sampling power of the nasal swab. The auxiliary support surface section 3 is used to transmit the driving force of the axial drive section 4 to the front brush section 1. The intermediate folded surface section 2 is used to provide assistance for the transmitted driving force and to buffer the pressure on the front brush section 1. The front brush section 1 is used to collect samples from the nasal cavity.

[0044] In this embodiment, the axial drive section 4 provides the inflation power source for the nasal swab, enabling sampling after inflation and providing a buffer for the inflation process. The auxiliary support surface section 3 provides support for the intermediate folded surface section 2. The intermediate folded surface section 2 provides axial and radial force variations for sampling, thereby driving the front brush section 1 to rotate and extend for sampling. The front brush section 1 directly contacts the subject's nasal cavity, increasing the sampling contact area. The connection with the intermediate folded surface section 2 allows the brush to elastically extend, contract, and rotate during sampling, thereby achieving automatic sampling and improving the sampling experience.

[0045] The front brush section 1 is a spherical cavity with multiple brushes evenly distributed on its surface. The bottom of the spherical cavity is connected to the middle folded surface section 2, and the top of the spherical cavity is a smooth plane.

[0046] In this embodiment, the smooth surface has no brushes, so that when it encounters resistance in contact with the nasal cavity, it will not increase the subject's stinging sensation. At the same time, the smooth surface can completely transmit the resistance encountered by the front brush segment 1 along the axial direction, avoiding force dispersion. The multiple brushes evenly distributed on the surface of the spherical cavity greatly increase the sampling coverage area. When the front brush segment 1 is rotated, the large area of ​​brushes can collect more samples at the same time.

[0047] The middle folded section 2 is a foldable cavity, which includes several layers of rings. The diameter of each ring decreases sequentially from back to front along the axial direction. When the middle folded section 2 is squeezed by the front brush section 1, the multiple rings are squeezed and then overlap and shrink from front to back along the axial direction.

[0048] In this embodiment, the intermediate folded surface section 2 includes four rings. When the front brush section 1 is obstructed in the nasal cavity, its smooth surface transmits the resistance axially to the intermediate folded surface section 2. Since the top diameter of the intermediate folded surface section 2 is small and the bottom diameter is large, the upper rings fold downward after being squeezed until all the rings are stacked and contracted.

[0049] Each ring layer includes multiple rhomboid faces, which are spliced ​​together along the circumferential direction to form a ring. When the middle folded surface segment 2 is squeezed by the front brush segment 1, the rhomboid faces on each ring layer convert the axial force into a tangential force, and the multiple ring layers rotate and fold along the circumferential direction.

[0050] In this embodiment, the hypotenuses of the multiple rhomboid faces on the ring are connected one after the other, and the upper and lower parallel edges of the rhomboid faces form the edge of the ring, so that the multiple rings remain parallel. When the middle folded section 2 is subjected to axial pressure, part of the force undergoes unstable deformation due to the special structure of the rhomboid face, converting the axial force into a tangential force, which drives the rotation of the rhomboid face.

[0051] The auxiliary support section 3 is a cylindrical cavity, with its top connected to the bottom of the middle folded section 2 and its bottom connected to the top of the axial drive section 4. The axial length of the auxiliary support section 3 is H3, the axial length of the middle folded section 2 is H2, and the axial length of the front brush section 1 is H1. H3 > H1 + H2.

[0052] In this embodiment, the cylindrical cavity of the auxiliary support surface section 3 always maintains a rigid, fixed cylindrical shape. Regardless of the inflation and stress states of the middle folded surface section 2 and the front brush section 1, it can maintain high-strength support to control the movement of the sampling direction and limit the transmission of force along the axial direction when sampling is obstructed. The greater the axial length of the auxiliary support surface section 3, the stronger the support force it provides.

[0053] The axial drive section 4 is a drum-shaped cavity, which includes a top drum surface and a bottom drum surface of the same diameter. The bottom drum surface is connected to the pressurizing device through a vent pipe. After being pressurized by the pressurizing device, the axial drive section 4 expands in the axial direction and pushes the front brush section 1 forward.

[0054] In this embodiment, the top and bottom drum surfaces of the axial drive section 4 have the same diameter. When the nasal swab is in a deflated state without inflation, the rigid top drum surface and the rigid auxiliary support surface section 3 support each other, allowing it to quickly deform into position and enter the sampling state during the next inflation. The bottom drum surface rapidly directs the gas generated by the pressurizing device along the shaped auxiliary support surface section 3 into the front brush section 1 through the vent pipe, thereby enabling rapid sampling by the front brush section 1.

[0055] The diameter of the top drum surface is D4, the diameter of the auxiliary support surface section 3 is D3, the diameter of the bottom of the middle folded surface section 2 is D22, the diameter of the top of the middle folded surface section 2 is D21, the diameter of the brush formed on the outer edge of the front brush section 1 is D1, and the diameter of the vent pipe is D5. D4 > D1 > D3 = D22 > D21 > D5.

[0056] In this embodiment, the diameter of the ventilation tube is much smaller than the diameter of the drumhead of the axial drive section 4 to increase the airflow velocity during inflation. The diameter of the auxiliary support section 3 is approximately half the diameter of the drumhead of the axial drive section 4. This satisfies both the diameter required to enter the nasal cavity and the need to provide sufficient support between the intermediate fold section 2 and the axial drive section 4. The top diameter of the intermediate fold section 2 is slightly smaller than its bottom diameter, with the difference being the sum of the wall thicknesses of the three rings. The diameter of the outer edge of the brush is larger than that of the intermediate fold section 2 and the auxiliary support section 3, ensuring that the brush makes full contact with the nasal cavity wall after entering the nasal cavity, thereby increasing the sample collection concentration. Example

[0057] This embodiment also provides a soft nasal swab sampling method based on aerodynamic growth, wherein the soft nasal swab includes the following steps:

[0058] S1. The subject remains still, the soft nasal swab is replaced and fixed, and the nasal swab is placed close to the lower part of the subject's nostrils by a robotic arm;

[0059] S2. Start the pressurization device to inflate the soft nasal swab. After the axial drive section 4, auxiliary support surface section 3, middle folding surface section 2, and front brush section 1 in the nasal swab expand in sequence, the front brush section 1 extends into the nasal cavity to prepare for sampling.

[0060] S3. After the front brush segment 1 is blocked at the sampling position inside the nasal cavity, the resistance is transmitted through the middle folded surface segment 2, so that the middle folded surface segment 2 is folded down and rotated in the circumferential direction at the same time.

[0061] S4. The front brush segment 1, which is connected to the intermediate folded surface segment 2, is driven to rotate, thereby collecting biological samples from inside the nasal cavity;

[0062] S5. After the nasal swab is collected, the front brush section 1 is placed in the collection box by the robotic arm, the pressurization device is turned off, the soft nasal swab is removed, and preparation is made for the next sampling.

[0063] Step S2 specifically includes:

[0064] S21. After the axial drive section 4 is inflated, the gas quickly enters the front brush section 1 through the cylindrical cavity, and the front brush section 1 extends into the nasal cavity.

[0065] S22. The axial drive section 4 and the auxiliary support section 3 provide support for the intermediate folding section 2. After continuous inflation, each layer of rings in the intermediate folding section 2 is fully unfolded.

[0066] S23. As the front brush section 1 gradually penetrates deeper, the forward resistance gradually increases. When it reaches the sampling position inside the nasal cavity, the squeezing resistance of the front brush section 1 is at its maximum, and this resistance is transmitted to the middle folded surface section 2.

[0067] Step S3 specifically includes:

[0068] S31. The top of the front brush section 1 is smooth and flat. When it reaches the sampling position inside the nasal cavity, it encounters the greatest resistance. The smooth and flat surface transmits the resistance axially to the top of the middle folded section 2.

[0069] S32. The top of the intermediate folded surface segment 2 transmits a portion of the resistance along the axial direction on its multi-layered rings to the bottom of the intermediate folded surface segment 2, and the multi-layered rings overlap along the axial direction under the action of this portion of resistance;

[0070] S33. The top of the intermediate folded surface segment 2 transmits another part of the resistance in the rhomboid surface of each ring along the tangential direction. Since the bottom of the intermediate folded surface segment 2 is connected to the auxiliary support surface segment 3, the auxiliary support surface segment 3 provides support for the bottom of the intermediate folded surface segment 2 and prevents this part of the resistance from continuing to be transmitted in the axial direction, so that the intermediate folded surface segment 2 rotates along the tangential circumferential direction under the action of this part of the resistance.

[0071] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the technical solution of the present invention, and are not intended to limit the specific implementation of the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the claims of the present invention should be included within the protection scope of the claims of the present invention.

Claims

1. A soft nasal swab based on aerodynamic growth, characterized in that, The nasal swab comprises an axial drive section, an auxiliary support surface section, an intermediate folded surface section, and a front brush section connected sequentially from back to front. The nasal swab is cavity-shaped. The axial drive section is used to control the gas filling in the cavity and the sampling power of the nasal swab. The auxiliary support surface section is used to transmit the driving force of the axial drive section to the front brush section. The intermediate folded surface section is used to provide assistance for the transmitted driving force and to buffer the pressure on the front brush section. The front brush section is used to collect samples from the nasal cavity.

2. The soft nasal swab based on pneumatic growth according to claim 1, characterized in that, The front brush section is a spherical cavity with multiple brushes evenly distributed on its surface. The bottom of the spherical cavity is connected to the middle folded surface section, and the top of the spherical cavity is a smooth plane.

3. A soft nasal swab based on pneumatic growth according to claim 1, characterized in that, The middle folded section is a foldable cavity, which includes several layers of rings. The diameter of each ring decreases sequentially from back to front along the axial direction. When the middle folded section is squeezed by the front brush section, the multiple rings are squeezed and then overlap and shrink from front to back along the axial direction.

4. A soft nasal swab based on pneumatic growth according to claim 3, characterized in that, Each ring layer includes multiple rhomboid faces, which are spliced ​​together along the circumference to form a ring. When the middle folded section is squeezed by the front brush section, the rhomboid faces on each ring layer convert the axial force into a tangential force, and the multiple ring layers rotate and fold along the circumference.

5. A soft nasal swab based on pneumatic growth according to claim 1, characterized in that, The auxiliary support surface segment is a cylindrical cavity, with its top connected to the bottom of the middle folded surface segment and its bottom connected to the top of the axial drive segment. The axial length of the auxiliary support surface segment is H3, the axial length of the middle folded surface segment is H2, and the axial length of the front brush segment is H1, where H3 > H1 + H2.

6. A soft nasal swab based on pneumatic growth according to claim 2, characterized in that, The axial drive section is a drum-shaped cavity, which includes a top drum surface and a bottom drum surface of the same diameter. The bottom drum surface is connected to the pressurizing device through a vent pipe. After being pressurized by the pressurizing device, the axial drive section expands in the axial direction and pushes the front brush section forward.

7. A soft nasal swab based on pneumatic growth according to claim 6, characterized in that, The diameter of the top drum surface is D4, the diameter of the auxiliary support surface section is D3, the diameter of the bottom of the middle folded surface section is D22, the diameter of the top of the middle folded surface section is D21, the diameter of the brush formed on the outer edge of the front brush section is D1, and the diameter of the vent pipe is D5. D4 > D1 > D3 = D22 > D21 > D5.

8. A soft nasal swab sampling method based on aerodynamic growth, characterized in that, The soft nasal swab according to any one of claims 1-7 comprises the following steps: S1. The subject remains still, the soft nasal swab is replaced and fixed, and the nasal swab is placed close to the lower part of the subject's nostrils by a robotic arm; S2. Activate the pressurization device to inflate the soft nasal swab. After the axial drive section, auxiliary support surface section, middle folding surface section and front brush section in the nasal swab expand in sequence, the front brush section extends into the nasal cavity to prepare for sampling. S3. After the front brush segment is blocked at the sampling position inside the nasal cavity, the resistance is transmitted through the middle folded surface segment, so that the middle folded surface segment is folded down and rotated in the circumferential direction at the same time. S4. The front brush segment connected to the intermediate folded surface segment is driven to rotate, thereby realizing the collection of biological samples inside the nasal cavity; S5. After the nasal swab is collected, the robotic arm places the front brush section into the collection box, turns off the pressurization device, removes the soft nasal swab, and prepares for the next sampling.

9. The sampling method according to claim 8, characterized in that, Step S2 specifically includes: S21. After the axial drive section is inflated, the gas quickly enters the front brush section through the cylindrical cavity, and the front brush section extends into the nasal cavity; S22. The axial drive section and the auxiliary support section provide support for the intermediate folded section. After continuous inflation, each layer of rings in the intermediate folded section is fully unfolded. S23. As the front brush segment gradually penetrates deeper, the forward resistance gradually increases. When it reaches the sampling position inside the nasal cavity, the squeezing resistance of the front brush segment is the greatest, and this resistance is transmitted to the middle folded surface segment.

10. The sampling method according to claim 8, characterized in that, Step S3 specifically includes: S31. The top of the front brush section is a smooth plane. When it reaches the sampling position inside the nasal cavity, it encounters the greatest resistance. The smooth plane transmits the resistance axially to the top of the middle folded section. S32. The top of the intermediate folded surface segment transmits a portion of the resistance along the axial direction on its multi-layered rings to the bottom of the intermediate folded surface segment, and the multi-layered rings overlap along the axial direction under the action of this portion of resistance; S33. The top of the intermediate folded surface segment transmits another part of the resistance in the rhomboid surface of each ring along the tangential direction. Since the bottom of the intermediate folded surface segment is connected to the auxiliary support surface segment, the auxiliary support surface segment provides support for the bottom of the intermediate folded surface segment and prevents this part of the resistance from continuing to be transmitted along the axial direction, so that the intermediate folded surface segment rotates along the tangential circumferential direction under the action of this part of the resistance.

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