Method for detecting state information of interventional pump, method for determining degree of cardiac recovery, and apparatuses therefor

Abstract

Disclosed are a method for detecting state information of an interventional pump, an apparatus for detecting state information of an interventional pump, a method for determining a degree of cardiac recovery, an apparatus for determining a degree of cardiac recovery, a blood pump apparatus, an electronic device, a computer-readable storage medium, and a computer program product. The method for detecting state information of an interventional pump comprises: when a pump head assembly in the interventional pump is transvalvularly placed into a heart for operation, acquiring a net pressure signal corresponding to the pump head assembly (310); on the basis of the net pressure signal, determining first reference data and / or second reference data (320); and according to the first reference data and / or the second reference data, outputting at least one type of state indication information (330), the at least one type of state indication information comprising at least one of cardiac recovery degree information, valve opening / closing state information, support level information, and suction risk information.

Description

Methods for detecting the status information of interventional pumps, methods for determining the degree of cardiac recovery, and related devices.

[0001] Cross-references to related applications

[0002] This application claims priority to Chinese Patent Application No. 202510065425.9, filed on January 15, 2025, entitled "Method, Apparatus, Device and Blood Pump for Detecting Status Information of Interventional Pump", and Chinese Patent Application No. 202510066325.8, filed on January 15, 2025, entitled "Method, Apparatus, Device and Blood Pump for Determining the Degree of Cardiac Recovery", the entire contents of which are incorporated herein by reference. Technical Field

[0003] This disclosure relates to the field of artificial heart technology, and in particular to a method and apparatus for detecting the status information of an interventional pump, and a method and apparatus for determining the degree of cardiac recovery. This disclosure also relates to blood pump devices, electronic devices, computer-readable storage media, and computer program products. Background Technology

[0004] Blood pump devices are used to provide mechanical circulatory support for patients. An interventional blood pump is a percutaneously implanted device within the patient's body. Its pump head is inserted percutaneously into the heart via a peripheral blood vessel. As the blades in the pump head rotate, they draw blood from the ventricles of the heart to the aorta, thus providing ventricular assist function. During operation, the level of blood pump support is a key indicator that the operator needs to control.

[0005] In related technologies, a pressure sensor is installed at the pump head of the blood pump device. The electronic equipment in the blood pump device determines the support level of the blood pump based on the speed signal transmitted back by the drive motor, and issues an alarm indicating that the blood pump support level is too high when the speed is too high, so as to instruct relevant personnel to take action.

[0006] However, the aforementioned technologies only determine the level of blood pump support based on the speed of rotation, which makes it difficult to truly reflect the level of blood pump support for the heart and to accurately determine abnormal states caused by excessive support levels.

[0007] In addition, the degree of cardiac recovery during the operation of the blood pump is a key indicator that the surgeon needs to pay attention to during the weaning phase. How to conveniently and accurately judge the degree of cardiac recovery through blood pump equipment has been a concern for those skilled in the art. Summary of the Invention

[0008] According to one or more embodiments of this disclosure, a method for detecting the status information of an interventional pump is provided. The method includes: acquiring a net pressure signal corresponding to the pump head assembly when the pump head assembly is inserted across a valve and operating within the heart; the net pressure signal characterizing the change in pressure difference between the blood outlet and blood inlet of the pump head assembly as the heart beats; determining first reference data and / or second reference data based on the net pressure signal; wherein the first reference data characterizes the opening status of the valve during the heartbeat cycle, and the second reference data characterizes the degree of support provided by the interventional pump to the heart; and outputting at least one status indication information based on the first reference data and / or the second reference data, the at least one status indication information including at least one of cardiac recovery degree information, valve opening / closing status information, support level information, and aspiration risk information; wherein the cardiac recovery degree information characterizes the degree of cardiac recovery, the valve opening / closing status information characterizes the opening / closing status of the valve during the heartbeat cycle, the support level information characterizes the level of support provided by the interventional pump for ventricular assist within the heart, and the aspiration risk information characterizes the likelihood of aspiration occurring within the heart.

[0009] According to one or more embodiments of the present disclosure, a method for determining the degree of cardiac recovery is provided, the method comprising: during a first period of operation of a pump head assembly in an interventional pump inserted across a valve into the heart, increasing the support level of the blood pump in response to a first adjustment command for the support level of the blood pump; determining a first critical support level in response to the occurrence of first valve state information during the first period, the first valve state information indicating that the valve is in a continuously closed state during at least one cardiac cycle, the first critical support level being a critical support level that keeps the valve in a continuously closed state during the first period; and outputting cardiac recovery degree information based on the first critical support level.

[0010] According to one or more embodiments of this disclosure, a status information detection device for an interventional pump is provided. The device includes: a net pressure acquisition module, configured to acquire a net pressure signal corresponding to the pump head assembly when the pump head assembly of the interventional pump is inserted across the valve and operating within the heart; the net pressure signal characterizes the change in the pressure difference between the blood outlet and blood inlet of the pump head assembly as the heart beats; a reference data determination module, configured to determine first reference data and / or second reference data based on the net pressure signal; wherein the first reference data characterizes the opening status of the valve during the heartbeat cycle, and the second reference data characterizes the degree of support provided by the interventional pump to the heart; and a status information output module, configured to output at least one status indication information based on the first reference data and / or the second reference data; the at least one status indication information includes at least one of heart recovery degree information, valve opening and closing status information, support level information, and aspiration risk information; wherein the heart recovery degree information characterizes the degree of heart recovery, the valve opening and closing status information characterizes the opening and closing status of the valve during the heartbeat cycle, the support level information characterizes the level of support provided by the interventional pump for ventricular assistance within the heart, and the aspiration risk information characterizes the possibility of aspiration occurring within the heart.

[0011] According to one or more embodiments of the present disclosure, an apparatus for determining the degree of cardiac recovery is provided. The apparatus includes: a blood pump control module for increasing the support level of the blood pump in response to a first adjustment command for the support level of the blood pump during a first period of operation of a pump head assembly in an interventional pump across a valve placed in the heart; a support level determination module for determining a first critical support level in response to the occurrence of first valve state information during the first period, the first valve state information indicating that the valve is in a continuously closed state during at least one cardiac cycle, the first critical support level being a critical support level that keeps the valve in a continuously closed state during the first period; and an information output module for outputting cardiac recovery degree information based on the first critical support level.

[0012] According to one or more embodiments of this disclosure, an electronic device is provided, the electronic device including a processor and a memory, the memory storing at least one instruction, at least one program, code set or instruction set, the at least one instruction, at least one program, code set or instruction set being loaded and executed by the processor to implement the above-described method for detecting the status information of the interventional pump and / or the above-described method for determining the degree of cardiac recovery.

[0013] According to one or more embodiments of this disclosure, a blood pump device is provided. The blood pump device includes a processor and a memory. The memory stores at least one instruction, at least one program, code set, or instruction set. The at least one instruction, at least one program, code set, or instruction set is loaded and executed by the processor to implement the above-described interventional pump status information detection method and / or the above-described method for determining the degree of cardiac recovery.

[0014] According to one aspect of the embodiments of this application, a computer-readable storage medium is provided, which stores at least one instruction, at least one program, code set or instruction set, wherein the at least one instruction, at least one program, code set or instruction set is loaded and executed by a processor to implement the above-described method for detecting the status information of the interventional pump and / or the above-described method for determining the degree of cardiac recovery.

[0015] According to one aspect of the embodiments of this application, a computer program product is provided, comprising computer instructions stored in a computer-readable storage medium. A processor of a computer device reads the computer instructions from the computer-readable storage medium and executes the computer instructions, causing the computer device to perform actions to implement the aforementioned method for detecting the status information of the interventional pump and / or the aforementioned method for determining the degree of cardiac recovery. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this disclosure, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this disclosure. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 is a schematic diagram of a blood pump device provided in an embodiment of this disclosure;

[0018] Figure 2 illustrates a schematic diagram of a connection between an interventional pump and a fluid pipeline.

[0019] Figure 3 is a flowchart of a method for detecting the status information of an interventional pump according to an embodiment of this disclosure;

[0020] Figure 4 illustrates an exemplary curve showing the relationship between net pressure signal and a first net pressure threshold under normal aortic valve opening and closing conditions.

[0021] Figure 5 illustrates an example of the relationship curve between a net pressure signal and a second net pressure threshold.

[0022] Figure 6 is a flowchart of a method for determining the degree of cardiac recovery provided in an embodiment of this disclosure;

[0023] Figure 7 is a block diagram of a status information detection device for an interventional pump provided in an embodiment of this disclosure; and

[0024] Figure 8 is a block diagram of a device for determining the degree of cardiac recovery provided in an embodiment of this disclosure. Detailed Implementation

[0025] To make the objectives, technical solutions, and advantages of this disclosure clearer, embodiments of this disclosure will be further described in detail below with reference to the accompanying drawings. Exemplary embodiments will be described in detail here, examples of which are illustrated in the accompanying drawings. When the following description refers to the drawings, unless otherwise indicated, the same numbers in different drawings represent the same or similar elements. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with this disclosure. Rather, they are merely examples of apparatuses and methods consistent with some aspects of this disclosure as detailed in the appended claims.

[0026] The terminology used in this disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. The singular forms “a,” “the,” and “the” as used in this disclosure and the appended claims are also intended to include the plural forms unless the context clearly indicates otherwise. It should also be understood that the term “and / or” as used herein refers to and includes any and all possible combinations of one or more of the associated listed items.

[0027] It should be understood that although the terms first, second, third, etc., may be used in this disclosure to describe various information, such information should not be limited to these terms. These terms are only used to distinguish information of the same type from one another.

[0028] Before introducing the method embodiments provided in this disclosure, a brief introduction will be given to the relevant technical background, related terms or nouns that may be involved in the method embodiments of this disclosure, so as to facilitate the understanding of those skilled in the art.

[0029] A blood pump device is a circulatory auxiliary device that replaces the function of the ventricles, including but not limited to external blood pump devices, interventional blood pump devices, and implantable blood pump devices.

[0030] An interventional blood pump device refers to a catheter-based pump used in medical settings to assist the heart in providing blood circulation. An interventional blood pump device includes an interventional blood pump (or simply interventional pump) and a control device used in conjunction with it, suitable for providing temporary ventricular circulation assistance during relevant surgeries. Optionally, the interventional pump is a cardiac pump inserted into a living organism. Optionally, some or all components of the interventional pump are inserted into the living organism. In operation, the drive device in the control device drives the interventional pump to pump blood from the ventricles into the aorta, assisting the heart's pumping function and reducing the burden on the heart.

[0031] Figure 1 is a schematic diagram of a blood pump device provided in an embodiment of this disclosure. Referring to Figure 1, the blood pump device is an interventional blood pump device, including an interventional pump 10 and a control device 20, which are detachably connected to the interventional pump 10. The interventional pump 10 is a consumable component.

[0032] The control device 20 includes, but is not limited to, a console 21, a drive motor 22, and a flushing device 23. The console 21 is used at least to respond to human-machine interface operations and system control operations, allowing operators to monitor system status and patient physiological data, and adjust the speed of the blood pump according to the patient's needs to provide different levels of circulatory assistance, thereby temporarily maintaining blood circulation to the patient's vital organs and relieving the burden on the heart. The drive motor 22 is used at least to drive the interventional pump 10.

[0033] The interventional pump 10 includes a drive catheter handle 11, a drive catheter 12, a pump head (or pump head assembly) 13, and a protective end 14. The pump head 13 includes, but is not limited to, an impeller, a support, and a diaphragm.

[0034] The interventional pump 10 can be percutaneously inserted into the heart through peripheral blood vessels. The pump head 13 is placed between the left ventricle and the aorta. The blood inlet of the pump head 13 is placed into the left ventricle, and the blood outlet of the pump head is placed into the aorta, thereby pumping blood from the left ventricle into the aorta to achieve ventricular assist function.

[0035] Since the interventional pump 10 needs to be inserted into the human body, it needs to be pre-charged before use and kept flushed during use to prevent air from entering the body through the gaps inside the interventional pump 10 and to prevent blood from stagnating in the gaps inside the interventional pump 10 and forming thrombi. Therefore, the interventional pump 10 can also be connected to a flushing line. The flushing device 23 is used to drive the flushing fluid in the flushing line to pre-charge, vent, and flush the gaps inside the interventional pump 10, thereby preventing blood from entering the drive catheter 12 and forming thrombi, and preventing air from entering the patient's body through the gaps inside the interventional pump and forming air embolisms. The flushing device 23 may include a peristaltic pump, which drives and squeezes the pump tube in the flushing line to pump the flushing fluid into the interventional pump 10, thereby preventing air bubbles from entering the drive catheter 12 of the interventional pump 10.

[0036] Optionally, the interventional pump system can monitor the blood pressure of the patient. The interventional pump has an arterial pressure measurement channel that remains connected to a blood vessel. An arterial pressure sensor is installed in the arterial pressure measurement channel; when the channel is connected to the blood vessel fluid, the sensor can detect the arterial pressure of the target patient. Therefore, the interventional pump 10 can also be connected to an arterial pressure measurement line. The arterial pressure measurement line has a periodically openable flushing valve. Pressure is applied to the fluid bag connected to the arterial pressure measurement line via a pressure bag, which can also drive fluid to flush the arterial pressure measurement path and prevent thrombosis.

[0037] As an example, see Figure 2, which exemplarily illustrates a schematic diagram of an interventional pump connected to a fluid line. The fluid line includes a flushing line and an arterial pressure monitoring line 40. The flushing line includes an infusion line 31, a circulation inlet line 32, and a circulation outlet line 33. The infusion line 31 can be driven and squeezed by the infusion pump 231 in the flushing device 23 (as shown in Figure 1), and the circulation inlet line 32 can be driven and squeezed by the circulation pump 232 in the flushing device 23.

[0038] After the drive catheter handle 11 is connected to the flushing pipeline, a flushing flow path is formed. Specifically, the flushing fluid inlet 111 of the drive catheter handle 11 is connected to the circulation inlet pipe 32 of the flushing pipeline, the flushing fluid outlet 112 of the drive catheter handle 11 is connected to the circulation outlet pipe 33 of the flushing pipeline, and the infusion pipe 31 of the flushing pipeline is connected to the fluid bag, forming the flushing flow path of the intervention pump 10. The infusion pump 231 drives the pump tube on the infusion pipe 31 to pump the flushing fluid in the fluid bag to the circulation inlet pipe 32, thereby driving the flushing fluid to enter the drive catheter handle 11 through the flushing fluid inlet 111. After the flushing fluid enters the drive catheter handle 11, part of it enters the drive catheter 12 through the flushing fluid chamber and is discharged to the human body from the pump head 13; the other part enters the coupling cooling chamber and flows back into the flushing pipeline from the flushing fluid outlet 112. The circulating pump 232 is used to drive the flushing fluid to circulate between the circulating inlet pipe 32, the drive guide handle 11, and the circulating outlet pipe 33 to cool the flushing fluid and prevent the high temperature generated by the coupled rotation between the drive motor 22 (as shown in Figure 1) and the intervention pump 10 (as shown in Figure 1) from causing the flushing fluid to reach a high temperature. At the same time, the circulating flushing fluid has a cooling effect on the coupled rotor.

[0039] After the drive catheter handle 11 is connected to the arterial pressure measurement tubing 40, an arterial pressure measurement flow path is formed. Specifically, the pressure measurement inlet 113 of the drive catheter handle 11 is connected to the arterial pressure measurement tubing 40, and the pressure measurement outlet 114 of the drive catheter handle 11 is connected to the pressure measurement interface 51 of the interventional sheath 50. The interventional sheath 50, after being percutaneously inserted into the blood vessel, provides a pathway for the interventional pump 10 to be placed into the heart, and the interventional sheath 50 remains in the patient's blood vessel until the interventional pump 10 is removed. The fluid in the fluid bag connected to the arterial pressure measurement tubing 40 fills the entire arterial pressure measurement channel in the arterial pressure measurement tubing 40 and the interventional pump 10, and connects to the gap 53 between the interventional sheath 50 and the drive catheter 12, thereby maintaining communication with the blood in the blood vessel. Thus, the arterial pressure sensor 115 in the interventional pump can detect the patient's arterial pressure. The aforementioned arterial pressure sensor 115 is located outside the patient's body.

[0040] In order to more accurately determine at least one of the following during the operation of the above-mentioned blood pump device: the level of support of the blood pump to the heart, the degree of heart recovery, and the state of the heart valves, this disclosure provides a method for detecting the status information of the interventional pump.

[0041] Please refer to Figure 3, which shows a flowchart of a method for detecting the status information of an interventional pump according to an embodiment of this disclosure. This method can be applied to electronic devices, which are those capable of data calculation and processing. For example, the executing entity for each step can be related electronic equipment in the blood pump device shown in Figure 1, such as the control console 21, the flushing device 23, etc. This method may include the following steps (310-330).

[0042] Step 310: When the pump head assembly in the interventional pump is inserted across the valve and running in the heart, acquire the net pressure signal corresponding to the pump head assembly.

[0043] The net pressure signal is used to characterize how the pressure difference between the blood outlet and blood inlet of the pump head assembly changes with the heartbeat.

[0044] The aforementioned net pressure signal can be obtained by detecting a pressure sensor installed at the pump head assembly, or it can be predicted based on the conversion of the interventional pump's operating signals. These operating signals include, but are not limited to, the current signal and rotational speed signal corresponding to the interventional pump. Since the pump head assembly of the interventional pump operates within the heart, the load on the pump head assembly changes periodically according to the heartbeat. Therefore, the aforementioned current and rotational speed signals contain AC components that match the heartbeat cycle. The pressure difference corresponding to the pump head assembly also changes periodically and has a conversion relationship with the AC components in the operating signals. Therefore, the aforementioned net pressure signal can be determined based on these operating signals.

[0045] Step 320: Determine the first reference data and / or the second reference data based on the net pressure signal.

[0046] The first reference data is used to characterize the opening of the valves during the heartbeat cycle, and the second reference data is used to characterize the degree of support provided by the interventional pump to the heart.

[0047] During a cardiac cycle, the magnitude of the net pressure signal is affected by factors such as the intensity of the heartbeat and the opening and closing motion of the aortic valve. For example, when the heartbeat intensity is high, the ventricular contractile force is greater, and the aortic valve can open faster and for a longer period under greater ventricular pressure. Once the aortic valve opens, the pressures at the inlet and outlet of the pump head assembly on both sides of the valve tend to converge, and the net pressure signal also approaches zero and remains so for a certain period of time. The speed and duration of the net pressure approaching zero are affected by the degree of heart health. Therefore, the aforementioned net pressure signal can reflect the valve's opening status during a cardiac cycle, and the first reference data can be determined based on the corresponding relationship.

[0048] Furthermore, the level of support the interventional pump provides to the heart also affects the net pressure signal. For example, if the support level is too high, blood flows from the ventricles to the arteries, reducing ventricular pressure. The heart valves may then remain closed throughout the heart cycle, resulting in a persistent pressure difference between the blood outlet and inlet on either side of the valves. This pressure difference may no longer be equal or approximately equal. Therefore, the net pressure signal reflects the degree of support the interventional pump provides to the heart, allowing the determination of the aforementioned second reference data based on this correlation.

[0049] Step 330: Output at least one status indication information based on the first reference data and / or the second reference data.

[0050] At least one status indication information includes at least one of cardiac recovery status information, valve opening and closing status information, and support level information.

[0051] Among them, cardiac recovery information is used to characterize the degree of cardiac recovery, valve opening and closing status information is used to characterize the opening and closing status of valves during the heartbeat cycle, and support level information is used to characterize the level of support provided by the interventional pump for ventricular assistance within the heart.

[0052] The technical solution provided in this disclosure, by acquiring the net pressure of the interventional pump head, can determine how the net pressure of the pump head changes with the heartbeat cycle. Since the movement of the heart valves and the degree of support of the interventional pump both affect the net pressure of the pump head, a first reference data that can characterize the opening of the heart valves and a second reference data that can characterize the degree of support of the interventional pump can be determined based on the net pressure of the pump head. Then, based on the first reference data and / or the second reference data, at least one of the following can be output: information on the degree of cardiac recovery, information on valve opening and closing status, information on support level, and information on aspiration risk. This allows the operator to quickly and intuitively judge the level of support of the blood pump for the heart and the relevant state of the heart.

[0053] In an exemplary embodiment, the aforementioned first reference data includes open state ratio information, which characterizes the proportion of the open duration within the heartbeat cycle. To determine the open state ratio information, the open duration of the valve in the open state during the heartbeat cycle can be determined based on the net pressure signal; based on the open duration, the open state ratio information can be determined.

[0054] In one possible implementation, a data interval in the net pressure signal that is less than or equal to a first net pressure threshold can be determined within the heartbeat cycle, where the duration corresponding to the data interval can be understood as the on-state duration. Accordingly, the proportion of the on-state duration within the heartbeat cycle is determined as the on-state ratio information.

[0055] In one example, as shown in Figure 4, an exemplary graph illustrates the relationship between the net pressure signal and a first net pressure threshold under normal aortic valve opening and closing conditions. The net pressure signal 410 shown in Figure 4 is compared with the first net pressure threshold 420, which indicates valve opening. Data points 411 that decrease to the first net pressure threshold 420 and 412 that rise back to the first net pressure threshold are identified. The data interval between data points 411 and 412 is the data interval in the net pressure signal 410 that is less than or equal to the first net pressure threshold 420. The time span between data points 411 and 412 is the initial duration t1. The duration of the heartbeat cycle is t2.

[0056] Optionally, the percentage of the heartbeat cycle duration Ropen can be determined using the following formula: Ropen = t1 / t2.

[0057] In an exemplary embodiment, after determining the first reference data, some indicators that are of concern to surgeons in clinical use can be output based on the first reference data, including but not limited to information on the degree of cardiac recovery and support level.

[0058] Optionally, based on the first reference data, information on the degree of cardiac recovery is output. The first reference data and the information on the degree of cardiac recovery are positively correlated. The better the cardiac recovery, the stronger the ventricular contraction capacity. Compared to a weak heart, a better-recovered heart will have a larger proportion of aortic valve opening time in the cardiac cycle. The aforementioned first reference data can be this proportion of time; therefore, the first reference data and the information on the degree of cardiac recovery are positively correlated.

[0059] Optionally, the aforementioned duration percentage Ropen can be used as information on the degree of cardiac recovery, or the aforementioned duration percentage can be normalized based on the maximum duration variation range of the aforementioned duration percentage, and the normalized data index can represent the information on the degree of cardiac recovery. This embodiment of the present disclosure does not limit the conversion relationship between the first reference data and the information on the degree of cardiac recovery.

[0060] Since there is a positive correlation between the aforementioned first reference data and the information on the degree of cardiac recovery, the change information corresponding to the first reference data can be determined. This change information can characterize the trend of change in the magnitude of the first reference data.

[0061] Without changing the target support level corresponding to the intervention pump, in response to the increase in the proportion of the activation duration in the heartbeat cycle indicated by the change information, the first cardiac state information is output, which is used to characterize the increased degree of cardiac recovery.

[0062] If the target support level corresponding to the intervention pump remains unchanged, in response to the decrease in the proportion of the activation duration in the heartbeat cycle indicated by the change information, second cardiac state information is output, which is used to characterize the reduced degree of cardiac recovery.

[0063] The aforementioned target support level refers to the expected support level that the interventional pump aims to achieve, such as target rotational speed and target flow rate; these are the set target values ​​for the interventional pump. If the target support level remains unchanged, it means that the amount of blood pump assistance to the heart has remained almost unchanged. The changes in the aforementioned first reference data, such as the valve opening duration percentage (Ropen), are caused by the heart itself. If Ropen increases, it means the heart is stronger and recovering better; if Ropen decreases, it means the heart is weaker and the recovery is slower.

[0064] When the proportion of valve opening time in the cardiac cycle is used as the first reference data, the heart's recovery status can be quickly determined by judging the trend of the change of the first reference data.

[0065] In addition to outputting the aforementioned cardiac recovery level information based on the first reference data, relative support level information can also be output based on the first reference data. The support level information includes relative support level information, which characterizes the relative relationship between the support level of the interventional pump and the heart's native pumping level.

[0066] Optionally, the first reference data mentioned above includes the proportion of activation duration in the heartbeat cycle, and the relative support level information mentioned above may include support level ratio data, which is used to characterize the ratio of the support level of the interventional pump to the original pumping level of the heart.

[0067] For example, a support level ratio of 0 indicates no interventional pump support (only native heart support); a support level ratio of 0.5 indicates equal support from the heart and interventional pump; a support level ratio of 1 (or 100%) indicates that the interventional pump has just replaced the native heart function; and a support level ratio of 1.5 (or 150%) indicates that the pump provides (approximately) 1.5 times the output provided by the native heart.

[0068] With the interventional pump support level remaining constant, the aforementioned duration percentages are positively correlated with the degree of cardiac recovery. Therefore, an increase in these duration percentages indicates an increase in cardiac recovery. Simultaneously, since the aforementioned relative support level ratios reflect how many times the pump support level is compared to the heart's native pumping level, it can be simply understood as the pump support level being the numerator and the heart's native pumping level being the denominator. If the degree of cardiac recovery increases, this ratio should decrease. Therefore, the aforementioned pump support level ratios are negatively correlated with the valve opening time percentage.

[0069] Since the supported horizontal ratio data is negatively correlated with the duration ratio, the supported horizontal ratio data can be determined based on the duration ratio of the activation time in the heartbeat cycle, and then the corresponding prompt information can be output.

[0070] This disclosure does not limit the conversion relationship between the duration percentage and the support level percentage data. Those skilled in the art can design specific conversion relationships to ensure that the above-mentioned duration percentage and support level percentage data maintain a negative correlation.

[0071] By outputting prompts corresponding to the support level ratio data, such as directly outputting the support level ratio data, more user-friendly indicators can be provided, allowing operators to quickly understand the relationship between the current blood pump support volume and cardiac support volume, thereby better adjusting the blood pump support level.

[0072] In addition to outputting the aforementioned cardiac recovery level and relative support level information based on the first reference data, blood pump support level information can also be output based on the first reference data. The support level information includes blood pump support level information, which characterizes the level of support the interventional pump provides to the heart.

[0073] Optionally, the blood pump support level information includes blood pump support level data, which is used to characterize the degree of support provided by the interventional pump for ventricular assist.

[0074] When the blood pump is running, it draws blood from the ventricles to the arteries, reducing the pressure in the left ventricle. The higher the blood pump support level, the lower the pressure in the left ventricle, and the more difficult it is for the blood in the ventricle to open the aortic valve. Therefore, the opening time of the aortic valve will decrease as the blood pump support level increases. Thus, the blood pump support level data is negatively correlated with the above-mentioned time percentage.

[0075] Since the blood pump support level data is also negatively correlated with the duration ratio, the blood pump support level data can be determined based on the proportion of the activation time in the heartbeat cycle, and then the corresponding prompt information can be output.

[0076] Similarly, this disclosure does not limit the conversion relationship between the duration percentage and the blood pump support level data. Those skilled in the art can design specific conversion relationships for specific blood pumps so that the above-mentioned duration percentage and blood pump support level data maintain a negative correlation.

[0077] By outputting prompts corresponding to the blood pump support level data, such as directly outputting the blood pump support level data, more user-friendly indicators can be provided, allowing the operator to quickly understand the current blood pump support level and thus better adjust the blood pump support level to prevent the risk of aspiration due to excessively high blood pump support levels.

[0078] In addition, aspiration risk information can also be output based on the first reference data. Optionally, the aspiration risk information includes aspiration alarm information and / or aspiration warning information. The aspiration alarm information indicates that aspiration has occurred within the heart, and the aspiration warning information indicates that there is a risk of aspiration occurring in the heart.

[0079] Optionally, when the aforementioned blood pump support level data exceeds a first threshold, a suction warning message can be issued to indicate that a suction event may occur. This suction warning message can be understood as a preventative alert. In this case, the valve opening time may be relatively small, so a direct correlation between the magnitude of the first reference data and the triggering of the suction warning message can also be established. This embodiment of the present disclosure does not limit this approach.

[0080] Optionally, when the aforementioned blood pump support level data is greater than a second threshold (the second threshold is greater than the first threshold), a suction alarm can be issued to indicate that a suction event has occurred in the heart. At this time, the valve opening time percentage may already be 0, and the aortic valve no longer opens. Therefore, a direct correspondence between the magnitude of the first reference data and the triggering of the suction alarm can also be established. This embodiment of the present disclosure does not limit this aspect.

[0081] The above section explains how to determine the first reference data and how to output relevant status information based on the first reference data. The following section introduces the second reference data.

[0082] The aforementioned second reference data is used to characterize the degree of support the interventional pump provides to the heart. When the interventional pump provides greater support to the heart, the valves in the heart, such as the aortic valve, may remain closed during the heartbeat cycle, resulting in a change in the net pressure signal. Therefore, the second reference data that can characterize the degree of support the interventional pump provides to the heart can be determined through the net pressure signal.

[0083] When the interventional pump support level is normal, the valves open and close normally. When the valves are open, the blood outlets and inlets on both sides of the valve are in a connected flow channel, and the pressure difference between the blood outlets and inlets on both sides of the valve can be close to 0. However, when the interventional pump support is too high, the valves may remain closed, which will result in a constant pressure difference between the blood outlets and inlets on both sides of the valve, and the two may no longer be equal or approximately equal. Valve opening usually occurs during ventricular systole, so it is often the systolic pressure difference that changes when the interventional pump support level is too high, for example, increasing from 0 to a value greater than 0.

[0084] Therefore, in the exemplary embodiment, systolic net pressure data in the net pressure signal can be determined, which characterizes the pressure difference of the pump head assembly when the heart is in ventricular systole; and the difference between the systolic net pressure data and a second net pressure threshold can be determined; this second net pressure threshold is the pressure difference threshold used to determine the valve's sustained closure. The second net pressure threshold can be a critical value, specifically the pressure difference corresponding to the pump head assembly at a critical support level that causes the valve to just stop opening. If it is desired to further determine how much the interventional pump's support level exceeds the normal level, the aforementioned difference data can be determined, because the magnitude of the systolic pressure difference varies at different levels of over-support. Therefore, a second reference data can be determined based on the difference data, and the second reference data is positively correlated with the difference data. The larger the difference data, the greater the degree of cardiac support provided by the interventional pump.

[0085] In one example, as shown in Figure 5, a graph illustrating the relationship between a net pressure signal and a second net pressure threshold is presented. The systolic net pressure data 511 in the net pressure signal 510 is at the trough of the net pressure signal 510. The aforementioned difference data can be obtained by comparing the systolic net pressure data 511 with the second net pressure threshold 520, which indicates that the valve is just continuously closed.

[0086] In one example, the above difference data Pclosed = Pmin - Pa. Where Pmin represents the minimum value in the net pressure signal, that is, the minimum value in the systolic net pressure data, or the mean value of the systolic net pressure data; Pa represents the second net pressure threshold.

[0087] In an exemplary embodiment, after determining the aforementioned second reference data, some indicators of clinical interest to the surgeon can be output based on the second reference data, including but not limited to information on the degree of cardiac recovery and support level. Both the second and first reference data can be used independently as reference data for determining the aforementioned status indicators.

[0088] Optionally, cardiac recovery degree information is output based on the second reference data; wherein, the second reference data and cardiac recovery degree information are negatively correlated.

[0089] As mentioned above, the difference data and the second reference data are positively correlated; the larger the difference data, the greater the support the interventional pump provides to the heart. The difference data is actually the net systolic pressure minus the second net pressure threshold. Therefore, the magnitude of the net systolic pressure determines the magnitude of the difference data. Net pressure is obtained by subtracting the inlet pressure (left ventricular pressure) from the outlet pressure (aortic pressure) of the blood pump. Therefore, as the heart recovers, the left ventricular pressure increases, resulting in a relative decrease in the net systolic pressure data, thus reducing the difference data and consequently decreasing the second reference data. Therefore, when using the second parameter data to assess the blood pump's support for the heart, if the second reference data decreases without changing the target support level of the blood pump, it means the net systolic pressure has decreased. However, in this case, the blood pump support level remains unchanged at the original target value. Therefore, the decrease in the second reference data is likely due to increased heart recovery and increased left ventricular systolic pressure. Thus, the aforementioned second reference data and information on the degree of heart recovery are negatively correlated.

[0090] Since there is a negative correlation between the aforementioned second reference data and the information on the degree of cardiac recovery, the change information corresponding to the second reference data can be determined. This change information can characterize the trend of change in the magnitude of the second reference data.

[0091] If the target support level corresponding to the interventional pump remains unchanged, in response to the decrease in the second reference data indicated by the change information, the first cardiac state information is output, which is used to characterize the increased degree of cardiac recovery.

[0092] In response to an increase in the second reference data indicated by the change information, without changing the target support level corresponding to the intervention pump, the second cardiac state information is output, which is used to characterize a decrease in the degree of cardiac recovery.

[0093] Correspondingly, if the second reference data increases when the target support level of the blood pump remains unchanged, it means that the net systolic pressure increases. However, in this case, the blood pump support level is still the original target value and has not changed. Therefore, the reason for the increase in net systolic pressure is likely due to the reduced degree of cardiac recovery and the decrease in left ventricular systolic pressure. Therefore, the above-mentioned second cardiac state information can be output when the second reference data increases.

[0094] In addition to outputting the above-mentioned cardiac recovery level information based on the second reference data, relative support level information can also be output based on the second reference data. The support level information includes relative support level information, which is used to characterize the relative relationship between the support level of the interventional pump and the original pumping level of the heart.

[0095] Optionally, the relative support level information includes support level ratio data, which is used to characterize the ratio of the interventional pump's support level to the heart's native pumping level.

[0096] During the operation of the interventional pump, assuming the degree of cardiac recovery remains constant, if the support level of the interventional pump increases, the left ventricular pressure will further decrease, and the net systolic pressure will increase accordingly. Therefore, the difference between the net systolic pressure and the second net pressure threshold will also increase, and the second reference data will increase accordingly. Since the support level ratio data represents the multiple of the interventional pump's support level to the original cardiac level, and the interventional pump support level is the numerator, the support level ratio data will increase. Therefore, there is a positive correlation between the second reference data and the support level ratio data.

[0097] The supported horizontal ratio data is positively correlated with the second reference data. Therefore, the supported horizontal ratio data can be determined based on the second reference data, and then the prompt information corresponding to the supported horizontal ratio data can be output.

[0098] By outputting prompts corresponding to the support level ratio data, such as directly outputting the support level ratio data, more user-friendly indicators can be provided, allowing operators to quickly understand the relationship between the current blood pump support volume and cardiac support volume, thereby better adjusting the blood pump support level.

[0099] In one example, to better describe the proportional relationship, the second reference data can be the ratio of the difference data to the third net pressure threshold, thereby representing the proportional magnitude in data form. Optionally, the second reference data Rclosed = (Pmin - Pa) / Pb, where Pb is the third net pressure threshold. The value of Pb can be determined based on experiments or experience and the type of interventional pump, and this disclosure does not limit this.

[0100] In addition to outputting the aforementioned cardiac recovery level and relative support level information based on the second reference data, blood pump support level information can also be output based on the second reference data. The support level information includes blood pump support level information, which characterizes the level of support the interventional pump provides to the heart.

[0101] Optionally, the blood pump support level information includes blood pump support level data, which is used to characterize the degree of support provided by the interventional pump for ventricular assist.

[0102] As mentioned earlier, during the operation of the interventional pump, assuming the degree of cardiac recovery remains constant, if the blood pump support level increases, the left ventricular pressure will further decrease, and the net systolic pressure will increase accordingly. Therefore, the difference between the net systolic pressure and the second net pressure threshold will also increase, and the second reference data will increase accordingly. Thus, the blood pump support level data and the second reference data are positively correlated.

[0103] The blood pump support level data is positively correlated with the second reference data. Therefore, the blood pump support level data can be determined based on the second reference data, and then the corresponding prompt information can be output. This embodiment does not limit the conversion relationship between the blood pump support level data and the second reference data; those skilled in the art can configure it according to the actual blood pump and experimental data.

[0104] By outputting prompts corresponding to the blood pump support level data, such as directly outputting the blood pump support level data, more user-friendly indicators can be provided, allowing the operator to quickly understand the current blood pump support level and thus better adjust the blood pump support level to prevent the risk of aspiration due to excessively high blood pump support levels.

[0105] In addition, the above-mentioned aspiration risk information can also be output based on the second reference data. Optionally, the aspiration risk information includes aspiration alarm information and / or aspiration warning information. The aspiration alarm information is used to indicate that aspiration has occurred within the heart, and the aspiration warning information is used to indicate that there is a risk of aspiration occurring in the heart.

[0106] Optionally, when the blood pump support level data exceeds the first threshold, a suction warning can be issued to indicate that a suction event may occur. This suction warning can be understood as a preventative alert. In this case, the difference may be small or negative; therefore, a direct correspondence between the size of the second reference data and the triggering of the suction warning can also be established. This embodiment of the present disclosure does not limit this approach.

[0107] Optionally, when the aforementioned blood pump support level data is greater than a second threshold (the second threshold is greater than the first threshold), a suction alarm can be issued to indicate that a suction event has occurred in the heart. At this time, the aortic valve may no longer be open, and the difference data is large. Therefore, a direct correspondence between the size of the second reference data and the triggering of the suction alarm can also be established. This embodiment of the present disclosure does not limit this approach.

[0108] The above is an embodiment of outputting relevant status indicators based solely on the first reference data and the second reference data. Alternatively, the first and second reference data can be used in combination for comprehensive judgment to output the aforementioned relevant status indicators. Therefore, the above-mentioned outputting at least one status indication information based on the first reference data and / or the second reference data may further include: outputting at least one status indication information based on the first reference data when the valve is in a normal opening and closing state; and outputting at least one status indication information based on the second reference data when the valve is in a continuously closed state.

[0109] Since the aforementioned first reference data characterizes the valve opening status during the cardiac cycle, it is determined based on the proportion of valve opening time. The data on this proportion is more sensitive when the valve is in a normal opening and closing state. Therefore, when the valve is in a normal opening and closing state, determining the aforementioned state indicators using the first reference data is more accurate. Furthermore, in this case, the conversion relationship between the first reference data and the aforementioned state indicators is simpler.

[0110] Since the second reference data is determined based on the difference between the net systolic pressure data and the second net pressure threshold, this difference is typically positive when the valve is continuously closed, and the data sensitivity is high. Therefore, when the valve is continuously closed, determining the aforementioned status indicators using the second reference data is more accurate. Furthermore, the conversion relationship between the second reference data and the aforementioned status indicators is simpler in this case. Thus, regardless of whether the valve is in a normal opening / closing state or continuously closed state, the device can comprehensively output accurate relevant status information.

[0111] To determine whether the valve is in a normal opening and closing state or in a continuously closed state, the net pressure signal can be compared with a first net pressure threshold to obtain a comparison result; the aforementioned first reference data can also include the comparison result, and the first net pressure threshold is a threshold used to indicate valve opening.

[0112] In response to a comparison result indicating that the net pressure signal is greater than a first net pressure threshold during at least one heartbeat cycle, first valve status information is output, which indicates that the valve is in a continuously closed state during at least one heartbeat cycle.

[0113] The aforementioned net pressure signal being greater than the first net pressure threshold can specifically mean that all net pressure data during systole are greater than the first net pressure threshold, or that the average net pressure data during systole is greater than the first net pressure threshold. The first net pressure threshold can be 0 or a positive number close to 0. With the aortic valve continuously closed, the left ventricular pressure is less than the aortic pressure; therefore, the net pressure may always be greater than 0. Thus, the above criterion can be used to identify a continuously closed valve.

[0114] In response to a comparison result indicating the presence of data less than or equal to a first net pressure threshold in the net pressure signal within at least one heartbeat cycle, a second valve status information is output, which indicates that the valve is in a normal opening and closing state within at least one heartbeat cycle.

[0115] When the aortic valve is normally open, the left ventricular pressure is approximately equal to the aortic pressure. Therefore, the net pressure may be 0 or even less than 0. This criterion can be used to identify whether the valve is in a normal opening and closing state. A normal opening and closing state means that the valve can alternately open and close during the cardiac cycle.

[0116] The above-described judgment rules can accurately determine whether the valve is in a normal opening and closing state or a continuously closed state, and can independently output the status information of the first valve and the second valve for the surgeon's reference. Simultaneously, based on the judged valve status information, appropriate reference data can be selected to determine and output other status indicators, such as the aforementioned cardiac recovery degree information and support level information. The support level information can be specifically divided into relative support level and blood pump support level.

[0117] Based on the above comparison results, in addition to determining whether it is in a normal opening / closing state or a continuously closed state, it is also possible to determine in real time whether the valve is in an open or closed state at the current moment.

[0118] In response to the occurrence of data less than or equal to a first net pressure threshold in the net pressure signal indicated by the comparison result, third valve status information is output, which indicates that the valve is in the open state. Optionally, the third valve status information is output at the moment when net pressure data less than or equal to the first net pressure threshold occurs, indicating in real time that the valve is in the open state at the aforementioned moment. Once the net pressure data exceeds the first net pressure threshold, the output of the third valve status information is canceled, and the fourth valve status information described below is output instead.

[0119] In response to a comparison result indicating that the net pressure signal contains data exceeding a first net pressure threshold, fourth valve status information is output. This fourth valve status information indicates that the valve is closed. Optionally, the fourth valve status information is output at the moment when net pressure data exceeding the first net pressure threshold occurs, indicating in real time that the valve is closed at that moment. Once the net pressure data is less than or equal to the first net pressure threshold, the output of the fourth valve status information is canceled, and the third valve status information described above is output instead.

[0120] By determining in real time whether the valve is open or closed, the surgeon can more easily know the current valve movement status.

[0121] As mentioned in the above embodiments, a critical support level that causes the valve to remain closed can be determined. This critical support level is also related to the degree of cardiac recovery. Therefore, this disclosure also provides a method for determining the degree of cardiac recovery. This method can be applied to electronic devices, which refer to electronic devices with data calculation and processing capabilities. For example, the executing entity for each step can be the relevant electronic device in the blood pump device shown in Figure 1, such as the control console 21, the flushing device 23, etc. Please refer to Figure 6, which shows a flowchart of a method for determining the degree of cardiac recovery provided in an embodiment of this disclosure. This method may include the following steps (610-630).

[0122] Step 610: During the first period of operation of the pump head assembly in the interventional pump across the valve in the heart, in response to the first adjustment command for the level of blood pump support, the level of blood pump support is increased.

[0123] The aforementioned first time period is a period of time during the operation of the intervention pump, such as a day or an hour. This embodiment of the disclosure does not limit the duration of the aforementioned first time period.

[0124] Optionally, the blood pump parameters used to characterize the support level of the blood pump include at least one of flow rate and rotational speed. Correspondingly, the first adjustment command for the blood pump support level is an adjustment command triggered within a first time period, and can be an adjustment command for the blood pump flow rate or an adjustment command for the blood pump rotational speed. The first adjustment command is used to control an increase in the blood pump support level. The first adjustment command can be automatically triggered by the device within the first time period or manually controlled; this disclosure does not limit this aspect.

[0125] Step 620: In response to the occurrence of the first valve status information during the first time period, determine the first critical support level.

[0126] The first valve status information is used to indicate that the valve is in a continuously closed state during at least one cardiac cycle. The first critical support level refers to the critical support level that keeps the valve in a continuously closed state during the first time period.

[0127] Optionally, during the first time period, the support level of the blood pump, such as pump speed and flow rate, can be continuously increased until the first valve status information appears, thereby determining the support level at the moment the first valve status information appears as the first critical support level.

[0128] Optionally, the parameter attributes corresponding to the critical support level are consistent with the parameter attributes corresponding to the blood pump support level. For example, if the adjusted blood pump support level is the rotational speed, then the first critical support level determined in the first time period is also the rotational speed.

[0129] Step 630: Output information on the degree of cardiac recovery based on the first critical support level.

[0130] When the interventional pump's pump head assembly operates within the heart, it draws blood from the ventricles into the arteries, effectively relieving pressure in the ventricles. The higher the support level of the interventional pump, the stronger the pressure relief, and the greater the decrease in left ventricular pressure. The aortic valve stops opening when ventricular pressure falls below the pressure threshold required to open it. The healthier the heart, the stronger the ventricular contraction, and the higher the systolic ventricular pressure. To reduce ventricular pressure to the point where it can no longer open the valve, the interventional pump needs to operate at a higher support level to lower the ventricular pressure to the point where the valve no longer opens.

[0131] Therefore, the technical solution provided in this disclosure, by increasing the support level of the blood pump, can determine the critical support level that just allows the valve to remain closed when the information of continuous valve closure appears, thereby accurately judging the degree of cardiac recovery based on the size of the critical support level.

[0132] There can be a correspondence between critical support levels and cardiac recovery information. Therefore, in an exemplary embodiment, a first critical support level can be compared with a first relationship to output cardiac recovery information. The first relationship characterizes the correspondence between one or more support levels and one or more pieces of cardiac recovery information, where the cardiac recovery information corresponds to the first critical support level in the first relationship.

[0133] Through the above correspondence, the relationship between critical support level and cardiac recovery can be quantified more accurately. Thus, when the critical support level is determined during the operation of the interventional pump, information on the degree of cardiac recovery can be output more accurately, providing the operator with a more accurate reference.

[0134] In one possible implementation, first cardiac rehabilitation information is output in response to a first critical support level being greater than or equal to a first support level threshold; and / or, second cardiac rehabilitation information is output in response to a first critical support level being less than the first support level threshold.

[0135] The first cardiac rehabilitation information is used to characterize the heart's return to normal, and the second rehabilitation information is used to characterize the heart's failure to return to normal. The information on the degree of cardiac recovery includes the first cardiac rehabilitation information and / or the second cardiac rehabilitation information.

[0136] One or more support levels include a first support level threshold, and one or more cardiac recovery information includes at least one of first cardiac rehabilitation information and second cardiac rehabilitation information.

[0137] The aforementioned first relationship may specifically include: a correspondence where the critical support level is greater than or equal to the first support level threshold for outputting first cardiac rehabilitation information, and a correspondence where the critical support level is less than the first support level threshold for outputting second cardiac rehabilitation information.

[0138] By comparing the aforementioned first critical support level with the first support level threshold, it is possible to quickly determine whether the heart has recovered and output corresponding recovery information to provide guidance to the surgeon.

[0139] In another possible implementation, the first critical support level is compared with multiple support level thresholds, and the cardiac health level information corresponding to the first critical support level is output, including the cardiac recovery degree information.

[0140] In this correspondence, different critical support levels correspond to different cardiac health grades, and different cardiac health grades can characterize different degrees of cardiac recovery. Therefore, the current first critical support level can be compared with multiple support level thresholds in the correspondence to determine a target support level threshold that matches the first critical support level. The target support level threshold can be the support level threshold closest to the first critical support level, or it can be the maximum support level threshold that is less than or equal to the first critical support level. This embodiment of the disclosure does not limit the matching relationship between the first critical support level and the target support level threshold. After determining the target support level threshold, the cardiac health grade corresponding to the target support level threshold can be used as the cardiac health grade corresponding to the first critical support level, and the prompt information of this cardiac health grade can be output so that the surgeon can understand the cardiac health status in the first time period.

[0141] Accordingly, if the cardiac rehabilitation information or cardiac health level information corresponding to the aforementioned first critical support level indicates that the heart has returned to normal, the device can also issue a prompt suggesting withdrawal; otherwise, it can issue a prompt not recommending withdrawal. Therefore, the above method can also include the following steps:

[0142] In response to a first critical support level indicating that the heart has returned to normal, a first weaning recommendation is output; and / or, in response to a first critical support level indicating that the heart has not returned to normal, a second weaning recommendation is output.

[0143] The first withdrawal suggestion information is a prompt message indicating that withdrawal is recommended, while the second withdrawal suggestion information is a prompt message indicating that withdrawal is not recommended.

[0144] The first critical support level can be used to determine the state of cardiac recovery and can also output weaning suggestions, making it easier for the operator to choose the appropriate time to wean during the weaning process.

[0145] In addition to assessing the degree of cardiac recovery solely based on the first critical support level corresponding to the first time period, the degree of cardiac recovery can also be assessed by comparing the critical support levels at different time periods. Accordingly, the above methods also include:

[0146] In the second period following the first period, the blood pump support level is increased based on the second adjustment instruction for the blood pump support level.

[0147] In response to the first valve status information appearing during the second time period, a second critical support level is determined. The second critical support level refers to the critical support level that keeps the valve in a continuously closed state during the second time period.

[0148] After obtaining the second critical support level, it can be combined with the first critical support level, and then the cardiac recovery degree information can be output based on the first critical support level and the second critical support level.

[0149] When the interventional pump's pump head assembly operates within the heart, it draws blood from the ventricles into the arteries, acting as a pressure reliever for the ventricles. The higher the support level of the interventional pump, the stronger the pressure relief, and the greater the decrease in left ventricular pressure. The aortic valve stops opening when ventricular pressure falls below the pressure threshold required to open it. The healthier the heart, the stronger the ventricular contraction, and the higher the systolic ventricular pressure. To reduce ventricular pressure to a level that prevents further valve opening, the interventional pump needs to operate at a higher support level. This means that the healthier the heart, the higher the critical support level required to keep the valves closed. Therefore, comparing the critical support levels of two phases can help determine if the heart has recovered. For example, if the second critical support level is higher than the first, it indicates that the heart's recovery in the second phase is greater than in the first.

[0150] The aforementioned second time period can be a fixed time period following the first time period, such as the first time period being the first day and the second time period being the second day. The second time period can also be a manually selected second time period, such as manually triggering the aforementioned second adjustment command to be considered as entering the second time period.

[0151] The second adjustment command is an instruction that adjusts the blood pump support level, triggered in the second time period, and its triggering mechanism is similar to that of the first adjustment command.

[0152] In response to a second critical support level being greater than a first critical support level, first cardiac state information is output, which characterizes an increase in the degree of cardiac recovery; and / or, in response to a second critical support level being less than a first critical support level, second cardiac state information is output, which characterizes a decrease in the degree of cardiac recovery; and / or, in response to a second critical support level being equal to a first critical support level, third cardiac state information is output, which characterizes an unchanged degree of cardiac recovery; the cardiac recovery information includes at least one of the first cardiac state information, the second cardiac state information, and the third cardiac state information.

[0153] Optionally, the first target support level before the increase in support level in the first time period and the second target support level before the increase in support level in the second time period can be the same target support level. Therefore, the magnitude of the support level increment can also be used to determine whether the heart is recovering better. The support level increment refers to the increment from the target support level before the increase to the critical support level. For example, the difference between the first critical support level and the target support level before the increase is the first support level increment, and the difference between the second critical support level and the target support level before the increase is the second support level increment. When the target support level is the same in both time periods, a relationship where the second critical support level is greater than the first critical support level and the second support level increment is greater than the first support level increment can both indicate an increased degree of heart recovery.

[0154] The above describes the scenario where the first valve status information appears in the second time period. If the blood pump support level increases to its upper limit during the second time period but the first valve status information does not appear, it indicates that the heart is recovering well. Therefore, if the first valve status information does not appear during the second time period, the first heart status information is output, which is used to characterize the increased degree of heart recovery.

[0155] In an exemplary embodiment, valve status information can be determined through the following process:

[0156] Obtain the net pressure signal corresponding to the pump head assembly. The net pressure signal is used to characterize the change in the pressure difference between the blood outlet and blood inlet of the pump head assembly as the heart beats.

[0157] The net pressure signal is compared with the first net pressure threshold to obtain the comparison result;

[0158] In response to a comparison result indicating that the net pressure signal is greater than or equal to a first net pressure threshold during at least one heartbeat cycle, the first valve status information is output.

[0159] The process for determining valve status information has been explained in the previous text and will not be repeated here.

[0160] The following are embodiments of the apparatus disclosed herein, which can be used to execute embodiments of the method disclosed herein. For details not disclosed in the apparatus embodiments of this disclosure, please refer to the embodiments of the method disclosed herein.

[0161] Please refer to Figure 7, which shows a block diagram of an interventional pump status information detection device according to an embodiment of this disclosure. This device has the function of implementing the above-described interventional pump status information detection method; the function can be implemented in hardware or by hardware executing corresponding software. This device can be a computer device or can be installed within a computer device. The device 700 may include: a net pressure acquisition module 710, used to acquire a net pressure signal corresponding to the pump head assembly when the pump head assembly in the interventional pump is inserted across the valve and operating in the heart, the net pressure signal being used to characterize the change in the pressure difference between the blood outlet and blood inlet of the pump head assembly with the heartbeat; a reference data determination module 720, used to determine first reference data and / or second reference data based on the net pressure signal; wherein the first reference data is used to characterize the opening status of the valve during the heartbeat cycle, and the second reference data is used to characterize the degree of support provided by the interventional pump to the heart; and a status information output module 730, used to output at least one status indication information according to the first reference data and / or the second reference data, the at least one status indication information including at least one of cardiac recovery degree information, valve opening and closing status information, support level information, and aspiration risk information; wherein the cardiac recovery degree information is used to characterize the degree of cardiac recovery, the valve opening and closing status information is used to characterize the opening and closing status of the valve during the heartbeat cycle, the support level information is used to characterize the level of support provided by the interventional pump for ventricular assist in the heart, and the aspiration risk information is used to characterize the possibility of aspiration occurring in the heart.

[0162] The technical solution provided in this disclosure, by acquiring the net pressure of the interventional pump head, can determine how the net pressure of the pump head changes with the heartbeat cycle. Since the movement of the heart valves and the degree of support of the interventional pump both affect the net pressure of the pump head, a first reference data that can characterize the opening of the heart valves and a second reference data that can characterize the degree of support of the interventional pump can be determined based on the net pressure of the pump head. Then, based on the first reference data and / or the second reference data, at least one of the following can be output: information on the degree of cardiac recovery, information on valve opening and closing status, information on support level, and information on aspiration risk. This allows the operator to quickly and intuitively judge the level of support of the blood pump for the heart and the relevant state of the heart.

[0163] Please refer to Figure 8, which shows a block diagram of a device for determining the degree of cardiac recovery according to an embodiment of this disclosure. This device has the function of implementing the above-described method for determining the degree of cardiac recovery; the function can be implemented in hardware or by hardware executing corresponding software. The device can be a computer device or can be installed within a computer device. The device 800 may include: a blood pump control module 810, used to increase the support level of the blood pump in response to a first adjustment command for the support level of the blood pump during a first period of operation of the pump head assembly in the interventional pump across the valve in the heart; a support level determination module 820, used to determine a first critical support level in response to the appearance of first valve state information during the first period, the first valve state information indicating that the valve is in a continuously closed state during at least one cardiac cycle, the first critical support level referring to the critical support level that keeps the valve in a continuously closed state during the first period; and an information output module 830, used to output cardiac recovery degree information based on the first critical support level.

[0164] The technical solution provided in this disclosure increases the support level of the blood pump, thereby determining the critical support level that allows the valve to remain closed when the valve closure information is received, and thus accurately judging the degree of cardiac recovery based on the magnitude of the critical support level.

[0165] It should be noted that the apparatus provided in the above embodiments is only illustrated by the division of the above functional modules when implementing its functions. In actual applications, the above functions can be assigned to different functional modules as needed, that is, the internal structure of the device can be divided into different functional modules to complete all or part of the functions described above. In addition, the apparatus and method embodiments provided in the above embodiments belong to the same concept, and the specific implementation process can be found in the method embodiments, which will not be repeated here.

[0166] One embodiment of this disclosure provides an electronic device. This electronic device can be a control console in a blood pump device, or a computer device within a flushing device of a blood pump device. The electronic device includes a processor and a memory. The memory stores at least one instruction, at least one program, code set, or instruction set. The processor loads and executes the at least one instruction, at least one program, code set, or instruction set to implement the interventional pump status information detection method and / or the method for determining the degree of cardiac recovery provided in the above embodiments. Specifically, the electronic device typically includes a processor and a memory.

[0167] The processor may include one or more processing cores, such as a quad-core processor or an octa-core processor. The processor may be implemented using at least one hardware form of DSP (Digital Signal Processing), FPGA (Field Programmable Gate Array), or PLA (Programmable Logic Array). The processor may also include a main processor and coprocessors. The main processor, also known as the CPU (Central Processing Unit), is used to process data in the wake-up state; the coprocessor is a low-power processor used to process data in the standby state. In some embodiments, the processor may integrate a GPU (Graphics Processing Unit), which is responsible for rendering and drawing the content to be displayed on the screen. In some embodiments, the processor may also include an AI (Artificial Intelligence) processor, which handles computational operations related to machine learning.

[0168] The memory may include one or more computer-readable storage media, which may be non-transitory. The memory may also include high-speed random access memory and non-volatile memory, such as one or more disk storage devices or flash memory devices. In some embodiments, the non-transitory computer-readable storage media in the memory is used to store at least one instruction, at least one program, code set, or instruction set, and is configured to be executed by one or more processors to implement the above-described method for detecting the status information of the interventional pump and / or the above-described method for determining the degree of cardiac recovery.

[0169] In some embodiments, the electronic device may also optionally include: a peripheral device interface and at least one peripheral device. The processor, memory, and peripheral device interface can be connected via a bus or signal line. Each peripheral device can be connected to the peripheral device interface via a bus, signal line, or circuit board. Specifically, the peripheral device includes at least one of: radio frequency circuitry, a touch display screen, a camera assembly, an audio circuit, a positioning assembly, and a power supply.

[0170] Those skilled in the art will understand that the above structure does not constitute a limitation on the electronic device, and may include more or fewer components, or combine certain components, or adopt different component arrangements.

[0171] In some possible implementations, the above-described method for detecting the status information of the interventional pump and / or the method for determining the degree of cardiac recovery described herein can be implemented in an electronic device. Some hardware electronic device platforms particularly suitable for implementation may be microcontrollers, FPGAs, operating system-based microprocessor platforms, or cloud computing platforms, etc. The former allows for faster and more direct access to data, while the latter is more likely to use complex models. It can also be implemented in analog circuits.

[0172] In an exemplary embodiment, a blood pump device is also provided, which includes a processor and a memory. The memory stores at least one instruction, at least one program, code set, or instruction set. The processor loads and executes the at least one instruction, at least one program, code set, or instruction set to implement the above-described method for detecting the status information of the interventional pump and / or the above-described method for determining the degree of cardiac recovery.

[0173] In an exemplary embodiment, a computer-readable storage medium is also provided, which stores at least one instruction, at least one program, code set, or instruction set, wherein the at least one instruction, at least one program, code set, or instruction set, when executed by a processor, implements the above-described method for detecting the status information of the interventional pump and / or the above-described method for determining the degree of cardiac recovery.

[0174] Optionally, the computer-readable storage medium may include: ROM (Read Only Memory), RAM (Random Access Memory), SSD (Solid State Drives), or optical disc, etc. The random access memory may include ReRAM (Resistance Random Access Memory) and DRAM (Dynamic Random Access Memory).

[0175] In an exemplary embodiment, a computer program product or computer program is also provided, which includes computer instructions stored in a computer-readable storage medium. A processor of a computer device reads the computer instructions from the computer-readable storage medium and executes the computer instructions, causing the computer device to perform the aforementioned method for detecting the status information of the interventional pump and / or the aforementioned method for determining the degree of cardiac recovery.

[0176] It should be understood that "multiple" as used herein refers to two or more. "And / or" describes the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A alone, A and B simultaneously, or B alone. The character " / " generally indicates that the preceding and following related objects are in an "or" relationship. Furthermore, the step numbers described herein are merely illustrative of one possible execution order. In some other embodiments, the steps may not be executed in numerical order, such as two steps with different numbers being executed simultaneously, or two steps with different numbers being executed in the reverse order of the illustration. This disclosure does not limit this.

[0177] Furthermore, in the specific embodiments of this disclosure, data such as user information are involved. When the above embodiments of this disclosure are applied to specific products or technologies, user permission or consent is required, and the collection, use and processing of related data must comply with the relevant laws, regulations and standards of the relevant countries and regions.

[0178] The above are merely exemplary embodiments of this disclosure and are not intended to limit this disclosure. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this disclosure should be included within the protection scope of this disclosure.

Claims

1. A method for detecting the status information of an interventional pump, wherein, The method includes: When the pump head assembly in the interventional pump is inserted across the valve and operates in the heart, the net pressure signal corresponding to the pump head assembly is acquired. The net pressure signal is used to characterize the change of the pressure difference between the blood outlet and blood inlet of the pump head assembly as the heart beats. Based on the net pressure signal, first reference data and / or second reference data are determined; wherein the first reference data is used to characterize the opening status of the valve during the cardiac cycle, and the second reference data is used to characterize the degree of support provided by the interventional pump to the heart; and Based on the first reference data and / or the second reference data, at least one status indication information is output, and the at least one status indication information includes at least one of cardiac recovery degree information, valve opening and closing status information, support level information, and aspiration risk information. The cardiac recovery degree information is used to characterize the degree of cardiac recovery, the valve opening and closing status information is used to characterize the opening and closing status of the valves during the heartbeat cycle, the support level information is used to characterize the support level of the interventional pump in the heart for ventricular assistance, and the aspiration risk information is used to characterize the possibility of aspiration occurring in the heart.

2. The method according to claim 1, wherein, The determination of the first reference data and / or the second reference data based on the net pressure signal includes: The duration of valve opening during the cardiac cycle is determined based on the net pressure signal; and Based on the activation duration, the activation state ratio information is determined, and the first reference data is used to characterize the proportion of the activation duration within the heartbeat cycle. The first reference data includes the on / off state ratio information.

3. The method according to claim 2, wherein, Determining the duration of valve opening during the heartbeat cycle based on the net pressure signal includes: During the heartbeat cycle, a data interval in the net pressure signal that is less than or equal to a first net pressure threshold is determined, the first net pressure threshold being a threshold used to indicate valve opening, wherein the duration corresponding to the data interval is the opening duration; and Based on the activation duration, the activation state ratio information is determined, including: The proportion of the activation duration within the heartbeat cycle is determined as the activation state ratio information.

4. The method according to claim 2, wherein, The step of outputting at least one status indication information based on the first reference data and / or the second reference data includes: Based on the first reference data, the cardiac recovery degree information is output; wherein, the first reference data and the cardiac recovery degree information are positively correlated; and / or Based on the first reference data, relative support level information is output, wherein the relative support level information is used to characterize the relative relationship between the support level of the interventional pump and the native pumping level of the heart; and / or Based on the first reference data, blood pump support level information is output, wherein the support level information includes the blood pump support level information, which is used to characterize the level of support the interventional pump provides to the heart; and / or Based on the first reference data, the aspiration risk information is output. The aspiration risk information includes aspiration alarm information and / or aspiration warning information. The aspiration alarm information is used to indicate that aspiration has occurred in the heart, and the aspiration warning information is used to indicate that there is a risk of aspiration in the heart.

5. The method according to claim 4, wherein, The step of outputting the cardiac recovery degree information based on the first reference data includes: Determine the change information corresponding to the first reference data; If the target support level corresponding to the interventional pump remains unchanged, in response to the change information indicating an increase in the proportion of the activation duration within the cardiac cycle, first cardiac state information is output, which characterizes the increased degree of cardiac recovery; and If the target support level corresponding to the interventional pump remains unchanged, in response to the change information indicating that the duration of the activation in the heartbeat cycle decreases, a second cardiac state information is output, which is used to characterize the reduced degree of cardiac recovery.

6. The method according to claim 4, wherein, The first reference data includes the proportion of the activation duration in the heartbeat cycle. Based on the first reference data, the output of relative support level information includes: Based on the proportion of the activation duration within the cardiac cycle, a support level ratio is determined; the relative support level information includes the support level ratio, which characterizes the ratio of the interventional pump's support level to the heart's native pumping level, and the support level ratio is negatively correlated with the duration proportion; and Output the prompt information corresponding to the supported horizontal ratio data.

7. The method according to claim 4, wherein, The first reference data includes the percentage of the activation duration within the heartbeat cycle. The step of outputting blood pump support level information based on the first reference data includes: Based on the proportion of the activation duration within the cardiac cycle, blood pump support level data is determined; the blood pump support level information includes the blood pump support level data, which characterizes the degree of ventricular assist provided by the interventional pump to the heart; the blood pump support level data is negatively correlated with the proportion of activation duration; and Output the prompt information corresponding to the blood pump support level data.

8. The method according to claim 1, wherein, The determination of the first reference data and / or the second reference data based on the net pressure signal includes: Determine the systolic net pressure data in the net pressure signal, wherein the systolic net pressure data characterizes the pressure difference of the pump head assembly corresponding to the state of ventricular systole of the heart; Determine the difference between the net systolic pressure data and the second net pressure threshold; and Based on the difference data, a second reference data is determined, and the second reference data is positively correlated with the difference data.

9. The method according to claim 8, wherein, The step of outputting at least one status indication information based on the first reference data and / or the second reference data includes: Based on the second reference data, the cardiac recovery degree information is output; wherein, the second reference data and the cardiac recovery degree information are negatively correlated; and / or Based on the second reference data, relative support level information is output, which includes the relative support level information used to characterize the relative relationship between the support level of the interventional pump and the native pumping level of the heart; and / or Based on the second reference data, blood pump support level information is output, the support level information including the blood pump support level information, which is used to characterize the level of support the interventional pump provides to the heart; and / or Based on the second reference data, the aspiration risk information is output, which includes aspiration alarm information and / or aspiration warning information. The aspiration alarm information is used to indicate that aspiration has occurred in the heart, and the aspiration warning information is used to indicate that there is a risk of aspiration in the heart.

10. The method according to claim 9, wherein, The step of outputting relative support level information based on the second reference data includes: Based on the second reference data, support level ratio data is determined; the relative support level information includes the support level ratio data, which characterizes the ratio of the interventional pump's support level to the heart's native pumping level, and the support level ratio data is positively correlated with the second reference data; and Output the prompt information corresponding to the supported horizontal ratio data.

11. The method according to claim 9, wherein, The step of outputting blood pump support level information based on the second reference data includes: Based on the second reference data, blood pump support level data is determined; the blood pump support level information includes the blood pump support level data, which characterizes the degree of ventricular assist provided by the interventional pump to the heart, and the blood pump support level data is positively correlated with the second reference data; and Output the prompt information corresponding to the blood pump support level data.

12. The method according to claim 1, wherein, The determination of the first reference data and / or the second reference data based on the net pressure signal includes: The net pressure signal is compared with a first net pressure threshold to obtain a comparison result. The first reference data includes the comparison result, and the first net pressure threshold is a threshold used to indicate valve opening. The step of outputting at least one status indication information based on the first reference data and / or the second reference data includes: In response to the comparison result indicating that the net pressure signal is greater than the first net pressure threshold during at least one of the heartbeat cycles, first valve status information is output, the first valve status information indicating that the valve is in a continuously closed state during the at least one heartbeat cycle; and / or, In response to the comparison result indicating that there is data less than or equal to the first net pressure threshold in the net pressure signal within at least one of the heartbeat cycles, second valve status information is output, which indicates that the valve is in a normal opening and closing state during the at least one heartbeat cycle.

13. The method according to claim 1, wherein, The determination of the first reference data and / or the second reference data based on the net pressure signal includes: The net pressure signal is compared with a first net pressure threshold to obtain a comparison result. The first reference data includes the comparison result, and the first net pressure threshold is a threshold used to indicate valve opening. The step of outputting at least one status indication information based on the first reference data and / or the second reference data includes: In response to the comparison result indicating that the net pressure signal contains data less than or equal to the first net pressure threshold, third valve status information is output, which indicates that the valve is in the open state; and / or In response to the comparison result indicating that the net pressure signal contains data greater than the first net pressure threshold, a fourth valve status information is output, which indicates that the valve is in a closed state.

14. The method according to any one of claims 1 to 13, wherein, The step of outputting at least one status indication information based on the first reference data and / or the second reference data includes: When the valve is in a normal opening and closing state, output at least one state indication information based on the first reference data; and When the valve is in a continuously closed state, the at least one state indication information is output according to the second reference data.

15. A method for determining the degree of cardiac recovery, wherein, The method includes: During the first period of operation of the pump head assembly in the interventional pump across the valve in the heart, in response to a first adjustment command to the level of support for the blood pump, the level of support for the blood pump is increased. In response to the occurrence of first valve status information during the first time period, a first critical support level is determined, wherein the first valve status information indicates that the valve is in a continuously closed state during at least one cardiac cycle, and the first critical support level refers to the critical support level that causes the valve to be in the continuously closed state during the first time period; and Information on the degree of cardiac recovery is output based on the first critical support level.

16. The method according to claim 15, wherein, The step of outputting cardiac recovery information based on the first critical support level includes: The first critical support level is compared with the first relationship to output the cardiac recovery degree information; the first relationship is used to characterize the correspondence between one or more support levels and one or more cardiac recovery degree information, and the cardiac recovery degree information corresponds to the first critical support level in the first relationship.

17. The method according to claim 16, wherein, The step of comparing the first critical support level with the first relationship and outputting the cardiac recovery degree information includes: In response to the first critical support level being greater than or equal to the first support level threshold, first cardiac rehabilitation information is output; and / or In response to the first critical support level being less than the first support level threshold, second cardiac rehabilitation information is output. Wherein, the first cardiac rehabilitation information is used to characterize the heart's return to normal, the second cardiac rehabilitation information is used to characterize the heart's failure to return to normal, and the cardiac recovery degree information includes the first cardiac rehabilitation information and / or the second cardiac rehabilitation information; the one or more support levels include the first support level threshold, and the one or more cardiac recovery degree information includes at least one of the first cardiac rehabilitation information and the second cardiac rehabilitation information.

18. The method according to claim 16, wherein, The first relationship includes a correspondence between multiple support level thresholds and multiple heart health level information. The step of comparing the first critical support level with the first relationship and outputting the heart recovery degree information includes: The first critical support level is compared with multiple support level thresholds, and the cardiac health level information corresponding to the first critical support level is output. The cardiac recovery degree information includes the cardiac health level information.

19. The method according to claim 15, wherein, The method further includes: In response to the first critical support level indicating that the heart has returned to normal, output first weaning recommendation information; and / or In response to the first critical support level indicating that the heart has not returned to normal, a second weaning recommendation is output; The first removal suggestion information is a prompt message indicating that removal of the aircraft is recommended, and the second removal suggestion information is a prompt message indicating that removal of the aircraft is not recommended.

20. The method of claim 15, wherein, The method further includes: In the second period following the first period, the support level of the blood pump is increased based on a second adjustment instruction for the support level of the blood pump; In response to the occurrence of the first valve state information during the second time period, a second critical support level is determined, wherein the second critical support level refers to the critical support level that would keep the valve in the continuously closed state during the second time period; and The step of outputting cardiac recovery information based on the first critical support level includes: outputting the cardiac recovery information based on the first critical support level and the second critical support level.

21. The method according to claim 20, wherein, The step of outputting the cardiac recovery level information based on the first critical support level and the second critical support level includes: In response to the second critical support level being greater than the first critical support level, first cardiac state information is output, which characterizes the increased degree of cardiac recovery; and / or In response to the second critical support level being less than the first critical support level, second cardiac state information is output, which characterizes the reduced degree of cardiac recovery; and / or In response to the second critical support level being equal to the first critical support level, third cardiac state information is output, which is used to characterize the degree of cardiac recovery remaining unchanged; The cardiac recovery information includes at least one of the first cardiac state information, the second cardiac state information, and the third cardiac state information.

22. The method according to claim 20, wherein, The method further includes: In response to the absence of the first valve status information during the second time period, the first heart status information is output, which is used to characterize the increased degree of recovery of the heart.

23. The method according to any one of claims 15 to 22, wherein, The method further includes: The net pressure signal corresponding to the pump head assembly is obtained, and the net pressure signal is used to characterize the change of the pressure difference between the blood outlet and blood inlet of the pump head assembly with the heartbeat. The net pressure signal is compared with a first net pressure threshold to obtain a comparison result; and In response to the comparison result indicating that the net pressure signal is greater than or equal to the first net pressure threshold during at least one of the heartbeat cycles, the first valve status information is output.

24. The method according to any one of claims 15 to 22, wherein, The blood pump parameters used to characterize the support level of the blood pump include at least one of flow rate and rotation speed, and the parameter attributes corresponding to the critical support level are consistent with the parameter attributes corresponding to the support level of the blood pump.

25. A device for determining the degree of cardiac recovery, wherein, The device includes: A blood pump control module is used to increase the support level of the blood pump in response to a first adjustment command for the support level of the blood pump during the first period of operation of the pump head assembly in the interventional pump across the valve placement in the heart. A support level determination module is configured to determine a first critical support level in response to the occurrence of first valve state information during the first time period, wherein the first valve state information indicates that the valve is in a continuously closed state during at least one cardiac cycle, and the first critical support level refers to the critical support level that causes the valve to be in the continuously closed state during the first time period; and The information output module is used to output information on the degree of cardiac recovery based on the first critical support level.

26. A status information detection device for an interventional pump, wherein, The device includes: The net pressure acquisition module is used to acquire the net pressure signal corresponding to the pump head assembly when the pump head assembly in the interventional pump is placed across the valve and running in the heart. The net pressure signal is used to characterize the change of the pressure difference between the blood outlet and blood inlet of the pump head assembly as the heart beats. A reference data determination module is configured to determine first reference data and / or second reference data based on the net pressure signal; wherein the first reference data characterizes the opening status of the valve during the cardiac cycle, and the second reference data characterizes the degree of support provided by the interventional pump to the heart; and The status information output module is used to output at least one status indication information based on the first reference data and / or the second reference data. The at least one status indication information includes at least one of cardiac recovery degree information, valve opening and closing status information, support level information, and aspiration risk information. The cardiac recovery degree information is used to characterize the degree of cardiac recovery, the valve opening and closing status information is used to characterize the opening and closing status of the valves during the heartbeat cycle, the support level information is used to characterize the support level of the interventional pump in the heart for ventricular assistance, and the aspiration risk information is used to characterize the possibility of aspiration occurring in the heart.

27. An electronic device, wherein, The electronic device includes a processor and a memory, the memory storing at least one instruction, at least one program, code set, or instruction set, the at least one instruction, the at least one program, the code set, or the instruction set being loaded and executed by the processor to implement the interventional pump status information detection method as described in any one of claims 1 to 14, and / or the method for determining the degree of cardiac recovery as described in any one of claims 15 to 24.

28. A blood pump device, wherein, The blood pump device includes a processor and a memory, wherein the memory stores at least one instruction, at least one program, code set, or instruction set, and the at least one instruction, the at least one program, the code set, or the instruction set is loaded and executed by the processor to implement the interventional pump status information detection method as described in any one of claims 1 to 14, and / or the method for determining the degree of cardiac recovery as described in any one of claims 15 to 24.

29. A computer-readable storage medium, characterized in that, The storage medium stores at least one instruction, at least one program, code set, or instruction set, wherein the at least one instruction, the at least one program, the code set, or instruction set is loaded and executed by a processor to implement the interventional pump status information detection method as described in any one of claims 1 to 14, and / or the method for determining the degree of cardiac recovery as described in any one of claims 15 to 24.

30. A computer program product, characterized in that, The computer program product includes computer instructions stored in a computer-readable storage medium, a processor of a computer device reading the computer instructions from the computer-readable storage medium, and the processor executing the computer instructions to cause the computer device to perform an action to implement the interventional pump status information detection method as described in any one of claims 1 to 14, and / or the method for determining the degree of cardiac recovery as described in any one of claims 15 to 24.

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