Hard water-resistant facial cleansing composition and use thereof in cosmetics

Abstract

A hard water-resistant facial cleansing composition and use thereof in cosmetics. The hard water-resistant facial cleansing composition comprises 0.8-5 parts by weight of lauryl hydroxysultaine, 0.1-0.7 parts by weight of sodium diethylenetriamine pentamethylene phosphonate, 0.045-0.3 parts by weight of sodium glucoheptonate, 0.08-1 part by weight of a skin conditioner A, and 0.01-0.5 parts by weight of a skin conditioner B. The skin conditioner A consists of 1,3-propanediol, 1,2-hexanediol, and octanoyl hydroxamic acid, and the skin conditioner B consists of glycerin and a leaf / stem extract of Stevia rebaudiana. The prepared hard water-resistant facial cleansing composition enhances the hard water resistance, reducing the influence of ions on the skin, and making up for the significant disadvantages of poor cleansing feel and ineffective cleansing in hard water of commercial facial cleansing products. The prepared hard water-resistant facial cleansing composition can be applied to most facial cleansing systems, and is widely used in the fields of skin care products, cosmetics, etc.

Description

A hard water resistant facial cleansing composition and its application in cosmetics.

[0001] This application claims priority to Chinese Patent Application No. 202510063709.4, filed on January 15, 2025, entitled "A hard water resistant facial cleansing composition and its application in cosmetics", the entire contents of which are incorporated herein by reference. Technical Field

[0002] This invention belongs to the field of skin care and cosmetics, and in particular relates to a hard water resistant facial cleansing composition and its application in cosmetics. Background Technology

[0003] Currently, the focus of the cleaning product market is gradually shifting towards gentleness. However, consumers often overlook the potential impact of ions in tap water on their skin. On one hand, the vast majority of consumers use tap water, especially in northern my country where water hardness is often high. Literature reports... 2+ At a concentration of 2.0 mmol / L, cell proliferation rapidly declines. At this concentration, cells may die or undergo apoptosis due to high calcium load, exhibiting certain cytotoxic effects and affecting the skin's self-renewal and metabolic rate. Urban water supply also leads to the adsorption and deposition of heavy metals due to long-distance transportation. Excessive iron and copper ions, when accumulated on the skin, enhance the generation of highly reactive oxygen free radicals, such as hydroxyl radicals, thereby stimulating oxidative damage and reacting with skin lipid peroxidation, causing inflammation. Furthermore, tap water contains pre-added disinfectants, the most common being chlorine disinfectants. Excessive residual chlorine concentration can damage skin cells and intercellular matrix, easily causing dry skin, cracking, papules, acne, aging, or palmar keratosis. Literature reports that these ions deposit on the skin surface, and tap water cannot effectively cleanse facial dirt. Therefore, the accumulation of these ions and dirt can cause irritation during cleansing, making washing the face with "plain water" not gentle.

[0004] Currently, commonly used surfactants in facial cleansers have poor detergency in hard water. Calcium and magnesium react with these surfactants to form insoluble calcium soap particles, clogging pores, forming plugs, affecting skin metabolism, and even causing premature aging. Water hardness also affects the foaming performance of surfactants, impacting the cleansing experience. While adding a single chelating agent as a water softener is common in cleansing formulations, simply adding something like disodium EDTA is insufficient to guarantee the stability of surfactants in hard water, and prolonged or excessive use can irritate the skin. The amount added in cleansers is also insufficient to address and cover ion-rich water environments. Intolerance to hard water means that in water with a certain degree of hardness, the activity of surfactants decreases, foaming performance is reduced, and the user experience deteriorates. Therefore, using ordinary cleansers in combination with hard water may exacerbate the harshness of the cleansing process.

[0005] Chinese patent document CN117297988A discloses an amino acid facial cleanser and its preparation method. This invention uses sodium cocoyl glycinate as the main component, which, when combined with surfactants potassium cocoyl glycinate, sodium lauroyl glutamate, cocoyl glutamate, and polyglycerol-10 laurate, increases the hard water resistance of the prepared facial cleanser, produces a large amount of stable and fine foam, and exhibits excellent moisturizing and cleansing abilities. However, the use of this composition is subject to limitations.

[0006] Chinese patent document CN116999341A discloses a hard water resistant composition, its preparation method, and its application. This patent only addresses the potential impact of calcium and magnesium ions in water on cleaning products, without considering the effects of other ions such as iron, copper, and chloride ions remaining in the water on human skin. Furthermore, the patent primarily addresses this issue through the formulation of surfactants, resulting in relatively weak deionizing capabilities. Summary of the Invention

[0007] To overcome the problems in the prior art, the present invention provides a hard water resistant facial cleansing composition and its application in cosmetics, which achieves coverage of various ions and more effectively reduces ion penetration residue. At the same time, when the composition of the present invention is added to a general facial cleansing system, it can also improve the long-term storage stability of the product in terms of odor, color, performance, etc., and help the system improve its anti-corrosion and antibacterial capabilities.

[0008] To solve the above-mentioned technical problems, the technical solution proposed by this invention is as follows:

[0009] This invention provides a hard water resistant facial cleansing composition comprising the following ingredients in parts by weight: lauryl hydroxysulfonate betaine, sodium diethylenetriaminepentamethylenephosphonate, sodium gluconate, skin conditioning agent A, and skin conditioning agent B, wherein skin conditioning agent A is 1,3-propanediol, 1,2-hexanediol, and capryloyl hydroxamic acid, and skin conditioning agent B is glycerin and stevia leaf / stem extract.

[0010] In this invention, the weight parts of each raw material in the hard water resistant facial cleansing composition are as follows: lauryl hydroxysulfonate betaine 0.24-1.5 parts by weight; sodium diethylenetriaminepentamethylenephosphonate 0.1-0.7 parts by weight; sodium gluconate 0.045-0.3 parts by weight; skin conditioning agent A 0.08-1 part by weight; skin conditioning agent B 0.01-0.5 parts by weight.

[0011] As an optional embodiment, in the facial cleansing composition provided by the present invention, the skin conditioning agent A, by weight, comprises 2-8 parts of capryloyl hydroxamic acid, 20-40 parts of 1,2-hexanediol, and 52-78 parts of 1,3-propanediol. In a specific embodiment, the skin conditioning agent A, by weight, comprises the following components: 5 parts of capryloyl hydroxamic acid, 30 parts of 1,2-hexanediol, and 65 parts of 1,3-propanediol.

[0012] As an optional embodiment, in the facial cleansing composition provided by the present invention, the skin conditioning agent B, by weight, comprises 49-61 parts glycerin, 36-46 parts water, and 3-5 parts stevia leaf / stem extract. In a specific embodiment, the skin conditioning agent B, by weight, comprises the following components: 55 parts glycerin, 41 parts water, and 4 parts stevia leaf / stem extract.

[0013] As an optional implementation, in the facial cleansing composition provided by the present invention, the skin conditioning B is prepared by subcritical fluid extraction.

[0014] As an optional implementation, in the facial cleansing composition provided by the present invention, the preparation method of the skin conditioning B includes the following steps:

[0015] Stevia leaves / stems were dried, pulverized using a pulverizer, filtered through a 60-mesh sieve, dried again, and stored for later use. A certain amount of the dried powder was weighed and added to a high-temperature, high-pressure reactor at a material-to-liquid ratio of 1:1 to 1:5. After stirring evenly, nitrogen gas was introduced to purge the gas. Subcritical extraction was performed at a pressure of 0.5–3 MPa and a temperature of 70–350 °C. After extraction, the subcritical aqueous extract was collected and centrifuged at 3000–8000 r / min for 5–15 min. The supernatant was evaporated and concentrated, and then mixed with glycerin to obtain sample skin conditioning agent B.

[0016] In some embodiments, the parts by weight of each ingredient in the hard water resistant facial cleansing composition are as follows: 1 part by weight of lauryl hydroxysulfonate betaine; 0.4 parts by weight of sodium diethylenetriaminepentamethylenephosphonate; 0.15 parts by weight of sodium gluconate; 0.5 parts by weight of skin conditioning agent A; and 0.1 parts by weight of skin conditioning agent B.

[0017] In other embodiments, the parts by weight of each ingredient in the hard water resistant cleansing composition are as follows: lauryl hydroxysulfonate betaine 0.24 parts by weight; sodium diethylenetriaminepentamethylenephosphonate 0.1 parts by weight; sodium gluconate 0.045 parts by weight; skin conditioning agent A 0.08 parts by weight; skin conditioning agent B 0.01 parts by weight.

[0018] In other embodiments, the parts by weight of each ingredient in the hard water resistant cleansing composition are as follows: 1.5 parts by weight of lauryl hydroxysulfonate betaine; 0.7 parts by weight of sodium diethylenetriaminepentamethylenephosphonate; 0.3 parts by weight of sodium gluconate; 1 part by weight of skin conditioning agent A; and 0.5 parts by weight of skin conditioning agent B.

[0019] Based on the same technical concept, the present invention also provides the application of the above-mentioned hard water resistant facial cleansing composition in the preparation of cleansing skin care products.

[0020] Based on the same technical concept, the present invention also provides a skin care product comprising the above-described cleansing composition.

[0021] In the skin care product, the mass of the hard water resistant cleansing composition is 0.475% to 4% of the mass of the cleansing product.

[0022] Based on the same technical concept, the present invention also provides the application of the above-mentioned hard water resistant facial cleansing composition in the preparation of cosmetics.

[0023] Based on the same technical concept, the present invention also provides a cosmetic product comprising the above-described facial cleansing composition.

[0024] In the cosmetic product, the mass of the hard water resistant facial cleansing composition is 0.475% to 4% of the mass of the facial cleansing product.

[0025] The lauryl hydroxysulfonate betaine in this invention is a hard water surfactant with a large number of hydrophilic groups and a straight-chain lipophilic group, exhibiting good hard water resistance and consistent foaming performance in both soft and hard water. Sodium diethylenetriaminepentamethylenephosphonate can be used over a wide pH range, can bind with free metal ions, rendering them inactive in catalytic oxidation, and effectively inhibits oxidation chain reactions and chemical decomposition, suppressing the formation of peroxide complexes, thereby maximizing the long-term stability of the final product. Sodium gluconate is a multivalent chelating agent; under the same conditions, its binding capacity is 2-3 times that of common chelating agents sodium gluconate and EDTA. When used as a binding agent in strongly alkaline media, sodium gluconate exhibits significantly better solubility and stability than sodium gluconate and EDTA. Stevia rebaudiana leaf / stem extract is an active ingredient extracted from organic leaves using subcritical water extraction technology. It has a high polyphenol content and can form stable complexes with metal ions on the skin, creating an ion-protective barrier and synergistically enhancing the effects of other active ingredients. Capryloyl hydroxamic acid is a commonly used preservative. Because its molecule contains oxygen and nitrogen atoms with lone pairs of electrons, and these atoms are close together, it can chelate with metal ions such as calcium, iron, magnesium, and aluminum to form stable multi-ring metal chelates. This effectively solves the interference of metal ions on cosmetic formulations, achieving the goal of stabilizing formulation quality.

[0026] The specific analysis is as follows:

[0027] Lauryl hydroxysulfonate betaine (LSDA) is a calcium soap dispersant, a type of hard water surfactant that enables soap to function as an effective laundry detergent in hard water, rather than forming insoluble calcium soap precipitates. Surfactants used as calcium soap dispersants must possess a large hydrophilic group (such as an ester, acid amine, or amino group as a linking group between the terminal hydrophilic and lipophilic groups) and a straight-chain lipophilic group. The large hydrophilic group in the calcium soap dispersant causes the mixed micelles, with the hydrophilic groups oriented towards the aqueous phase, to remain convex towards the aqueous phase. In hard water, the micelles formed by the soap molecules themselves are considered to be reversed, with the lipophilic group facing the aqueous phase, resulting in insoluble calcium soap.

[0028] Sodium diethylenetriaminepentamethylenephosphonate can be used over a wide pH range. It can integrate with free metal ions, causing them to lose their catalytic oxidation activity. Furthermore, it can effectively prevent oxidation chain reactions and chemical decomposition of substances, and inhibit the formation of peroxide complexes, thereby maximizing the protection of the long-term stability of the final product.

[0029] Sodium gluconate is one of the few natural chelating agents that can perform super-strong chelation under strongly alkaline conditions, especially at pH above 11. As a starch derivative, sodium gluconate is a leading bio-based new material in China. It can also be used as an antioxidant to help protect the skin from free radical damage. Furthermore, it can act as a moisturizer, enhancing the product's ability to retain moisture and keeping the skin hydrated.

[0030] In skin conditioning agent A, 1,2-hexanediol is considered one of the mildest diols, harmless to the human body, and possesses good antibacterial and moisturizing effects. Secondly, capryloyl hydroxamic acid is a commonly used, highly efficient, and selective metal ion chelating agent. Its molecule contains oxygen and nitrogen atoms with lone pairs of electrons, and the oxygen and nitrogen atoms are relatively close together, enabling them to react with Ca... 2+ Fe 3+ Mg 2+ Al 3+ When octanoyl hydroxamic acid chelates with metal ions, it forms stable multi-ring metal chelates. This is because octanoyl hydroxamic acid can form a unique three-dimensional structure, effectively chelating various metal ions, including highly efficient iron ions, which are essential nutrients for mold growth. Furthermore, in its preservative applications, octanoyl hydroxamic acid is gentler and safer because it does not directly attack microbial cells, but rather blocks or destroys the pathway by which microbial cells acquire iron ions.

[0031] Skin Conditioner B is a transparent liquid containing stevia leaf / stem extract. It has a high polyphenol content extracted using subcritical water extraction technology, which can form stable complexes with metal ions on the skin, forming an ion protective barrier film for the skin and synergistically enhancing the effects of other active ingredients.

[0032] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0033] In this invention, sodium diethylenetriaminepentamethylenephosphonate, sodium gluconate, and stevia leaf / stem extract mutually enhance each other, resulting in a synergistic effect that improves ion chelation capacity and addresses the potential risks posed by ions in plain water. Simultaneously, skin conditioning agent A and lauryl hydroxysulfonate betaine also have an additive effect on the active ingredients. Furthermore, the aforementioned active ingredients synergistically work with skin conditioning agent A to provide antiseptic and antibacterial effects. Finally, these three aspects work synergistically and are indispensable for achieving optimal results. The composition of this invention comprehensively enhances resistance to hard water, reduces the impact of ions on the skin, and overcomes the significant shortcomings of commercially available facial cleansers, such as poor washing feel and ineffectiveness due to their varying degrees of hardness. It increases the stability of cleansing products. Moreover, the composition of this invention is gentle and non-irritating, enabling the development of products gentler than simply washing the face with water. It can be applied to most facial cleansing systems and is widely used in skincare and cosmetics. Attached Figure Description

[0034] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0035] Figure 1 shows the test results of the calcium ion chelating ability of the facial cleansing compositions in the embodiments and comparative examples of the present invention;

[0036] Figure 2 shows the test results of the iron ion chelating ability of the facial cleansing compositions in the embodiments and comparative examples of the present invention.

[0037] Figure 3 shows the inhibitory effect of the facial cleansing composition of the present invention on the release of IL-6;

[0038] Figure 4 shows the effect of the facial cleansing composition of the present invention on human heme;

[0039] Figure 5 is a comparative diagram of the facial cleansing composition in Example 1 of the present invention and the control facial cleanser;

[0040] Figure 6 shows the sensory evaluation results of the facial cleansing composition in Example 1 of this invention and the control facial cleanser. Detailed Implementation

[0041] To facilitate understanding of the present invention, the present invention will be described more fully and in detail below with reference to the accompanying drawings and preferred embodiments, but the scope of protection of the present invention is not limited to the following specific embodiments.

[0042] Unless otherwise defined, all technical terms used herein have the same meaning as commonly understood by those skilled in the art. The technical terms used herein are for the purpose of describing particular embodiments only and are not intended to limit the scope of the invention.

[0043] Unless otherwise specified, all raw materials, reagents, instruments and equipment used in this invention can be purchased from the market or prepared by existing methods.

[0044] Example 1

[0045] A hard water-resistant facial cleansing composition comprises the following ingredients: lauryl hydroxysulfonate betaine, sodium diethylenetriaminepentamethylenephosphonate, sodium glucono-p-glucopyranoate, skin conditioning agent A, and skin conditioning agent B. Skin conditioning agent A consists of 1,3-propanediol, 1,2-hexanediol, and capryloyl hydroxamic acid, while skin conditioning agent B consists of glycerin and stevia leaf / stem extract. Skin conditioning agent A, by weight, comprises the following components: 5 parts capryloyl hydroxamic acid, 30 parts 1,2-hexanediol, and 65 parts 1,3-propanediol. Skin conditioning agent B, by weight, comprises the following components: 55 parts glycerin, 41 parts water, and 4 parts stevia (Stevia rebadia) leaf / stem extract. Details are shown in Table 1 below.

[0046] Table 1: Raw material ratios (parts by weight) of the facial cleansing compositions in the Examples and Comparative Examples

[0047] The preparation method for skin conditioning agent B is as follows: Stevia leaves / stems are dried, pulverized using a pulverizer, filtered through a 60-mesh sieve, dried again, and stored for later use. A certain amount of dried powder is weighed and added to a high-temperature and high-pressure reactor at a material-to-liquid ratio of 1:1 to 1:5. After stirring evenly, nitrogen gas is introduced to purge the gas. Subcritical extraction is carried out at a pressure of 0.5–3 MPa and a temperature of 70–350℃. After extraction, the subcritical aqueous extract is collected and centrifuged at 3000–8000 r / min for 5–15 min. The supernatant is evaporated and concentrated, and then mixed with glycerin to obtain sample skin conditioning agent B.

[0048] Examples 2-3

[0049] The hard water resistant facial cleansing compositions in Examples 2 and 3 differ from those in Example 1 mainly in the different raw material ratios, as detailed in Table 1 above.

[0050] Comparative Examples 1-6

[0051] The main difference between the hard water resistant facial cleansing compositions in Comparative Examples 1 to 6 and Example 1 is the different raw material ratios, as detailed in Table 1 above.

[0052] The effectiveness of the hard water-resistant facial cleansing compositions in the examples and comparative examples was verified as follows:

[0053] (1) Chelating ability test of the composition

[0054] 1) Calcium ion chelation capacity test

[0055] Test principle: Adjust the pH of the solution to about 10. The chelating agent has the ability to complex calcium ions. When the calcium ions are saturated, the calcium ions combine with the oxalate ions to form calcium oxalate precipitate that is insoluble in water, which is the endpoint of the titration.

[0056] Experimental methods:

[0057] Weigh approximately 5g of the integrator, dissolve it in water, and dilute to a 500mL volumetric flask. Pipette 10mL of the solution, add 5mL of ammonia-ammonium chloride buffer solution to adjust the pH to approximately 10, then add 1mL of 3% sodium oxalate solution. Titrate with calcium acetate standard solution until the solution becomes turbid. x=(cV100) / (m×10 / 500)

[0058] In the formula: c is the concentration of calcium acetate standard solution, mol / L; V is the volume of calcium acetate standard solution consumed in the titration, mL; m is the mass of chelating agent, g; 100 is the molar mass of CaCO3.

[0059] The chelation capacity results are shown in Table 2.

[0060] Table 2: Test results of the chelating ability of the facial cleansing compositions in the examples and comparative examples for calcium ions.

[0061] Comparative Example 1 used a traditional anionic surfactant; Comparative Example 2 replaced the synergistic chelating agent combination with commonly used EDTA-2Na; Comparative Example 3 replaced the preservative composition skin conditioning agent A with commonly used sodium benzoate; Comparative Examples 4, 5, and 6 respectively removed the other two aspects: the synergistic hard water surfactant, the hard water preservative composition, and the plant extract. As shown in Table 2 and Figure 1, the compositions provided in Examples 1-3 have strong calcium ion chelating ability, and this ability is significantly improved compared to using a single chelating agent. When the main active ingredient in the composition is replaced, its chelating ability decreases significantly, and removing the two synergistic surfactants and the preservative composition also results in a certain degree of decrease. Furthermore, by comparing Comparative Examples 1, 4, 3, 5, and 6, it can be seen that when ordinary surfactants and ordinary preservatives are used, there is almost no added benefit to the overall efficacy of the combination.

[0062] 2) Iron ion chelation ability test

[0063] Experimental Method: Accurately weigh 5.000 g of sample, dissolve in deionized water, transfer to a 500 mL volumetric flask, and dilute to the mark. Mix well and set aside. Transfer 2 mL of the sample solution to a 250 mL Erlenmeyer flask, add 30 mL of water and 0.2 g of 2% sulfosalicylic acid, and titrate with 0.01 mol / L ferric ammonium sulfate standard solution until the solution changes from colorless to a slightly pinkish hue. The calculation formula is as follows: X = Vc × 159.6 × 500 / m × 2

[0064] In the formula, V is the volume (mL) of ferric ammonium sulfate solution consumed by the sample; c is the concentration (mol / L) of the ferric ammonium sulfate solution; and m is the sample mass (g).

[0065] The chelation capacity results are shown in Table 3.

[0066] Table 3: Test results of the chelating ability of the cleansing compositions in the examples and comparative examples for iron ions.

[0067] As shown in Table 3 and Figure 2, the compositions provided in Examples 1-3 of this invention also exhibit strong chelating ability for iron ions. When the main active ingredient in the composition is replaced, its chelating ability decreases significantly. Removing the two synergistically active components, surface activity and preservatives or extracts, also results in a certain degree of decrease. Furthermore, by comparing Comparative Examples 1 and 4, Comparative Examples 3, Comparative Examples 5 and 6, it can be seen that using common surfactants and common preservatives provides almost no added benefit to the overall efficacy of the composition.

[0068] (2) Dechlorination capacity test

[0069] Experimental Method: A simulated tap water disinfection process was conducted, referencing the "Standards for Drinking Water Quality" GB5749-2022, to prepare high-chlorine water. Water and the test solution were mixed at a ratio of 90:10, stirred for 1 minute, and then the free chlorine content was determined using a residual chlorine water quality analyzer. The test results before and after chlorination are shown in Table 4 below.

[0070] Table 4: Chlorine removal results of the facial cleansing compositions in the examples and comparative examples

[0071] The test results for chloride ion removal are shown above. The compositions provided in Examples 1-3 of this invention also exhibit excellent chloride ion removal effects. Furthermore, a comparison of Comparative Example 1 and Comparative Example 2 shows that sodium diethylenetriaminepentamethylenephosphonate, sodium gluconate, and Chrysanthemum leaf / stem extract significantly enhance chloride removal compared to EDTA-2Na.

[0072] (3) Hard water resistance test

[0073] Test Method: The experiment followed the "Standards for Drinking Water Quality" GB5749-2022, and high-calcium and magnesium ion water was prepared. Take 50 mL of the test solution and let it flow down the cylinder wall, marking the liquid level inside the graduated cylinder as the initial graduation. Then, use the graduated cylinder to slowly pour 500 mL of the test solution into the separatory funnel, ensuring the measuring tube connected to the bottom of the separatory funnel is positioned at the 450 mm graduation mark on the level of the 50 mL test solution inside the inner graduated cylinder. Open the control valve of the separatory funnel, allowing the test solution to flow continuously until the liquid level in the separatory funnel drops to the 150 mm graduation mark and stops. Close the control valve, and measure the foam volume (foam only) in the graduated cylinder 30 seconds after the flow stops. Record the data and take the average value. Hard water resistance ratio = (hard water bubble volume / soft water bubble volume) × 100%

[0074] The test results for resistance to hard water are shown in Table 5 below.

[0075] Table 5: Hard water resistance test results in the examples and comparative examples

[0076] Experimental results show that commonly used surfactants in commercial facial cleansers have poor resistance to hard water, exhibiting significant differences in foaming ability in both soft and hard water. However, the composition of this invention, when added to commonly used surfactant systems in commercial facial cleansers, consistently demonstrates good foaming capacity without significant differences in either soft or hard water, exhibiting excellent resistance to hard water.

[0077] (4) Corrosion resistance test

[0078] Test Method: Example 1 was added to the cleansing system of the blank formulation to prepare a cleansing product, which was then compared and verified with the blank sample. By adding a mixture of microorganisms to the sample, typically bacteria and fungi (molds, yeasts) are mixed together during testing. This method simulates the characteristics of microbial coexistence in nature. Referring to internationally accepted standards for cosmetic preservative challenges, the determination was based on the logarithmic decrease in microbial content on days 2, 7, 14, 21, and 28.

[0079] The comparison cleanser - blank formula is shown in Table 6 below.

[0080] Table 6: Comparison of Cleansing and Blank Formulas

[0081] The results of the corrosion resistance test are shown in Table 7 below.

[0082] Table 7: Anti-corrosion results of the facial cleansing compositions in the examples and comparative examples

[0083] The results of the preservation challenge are shown above. As can be seen from Table 7, 1% phenoxyethanol alone in a normal amino acid facial cleanser system failed the preservation test; the reduction rate of bacteria and fungi mixture within 7 days did not reach below 99.9%, only around 70%. However, after adding Example 1, no significant increase in bacteria and mold was observed in the 28-day test, and the surface preservation test was passed. The composition of the present invention can assist normal facial cleanser systems in strengthening preservation.

[0084] (5) System stability comparison test

[0085] Test Method: The cleansing product was prepared by adding Example 1 to the blank formula, and then compared and verified with the blank sample. The color change of the cleansing sample under high temperature and light exposure was compared for evaluation. The blank sample had the same formula as in the above experiment.

[0086] The results are shown in Table 8 below.

[0087] Table 8: Comparison of stability results of facial cleansing composition systems in the examples and comparative examples

[0088] In facial cleansing systems, especially transparent cleansing liquid systems, amino acid surfactants or pigments often change color under prolonged high temperatures and light exposure, such as darkening, which affects the stability and appearance of the system. Example 1 of this invention has strong antioxidant and anti-chemical decomposition effects, effectively improving the long-term storage stability of cleaning products in terms of odor, color, and performance. Observations in a light chamber for 2 hours and 60 days at a high temperature of 48°C showed that the product without the added composition exhibited a noticeable yellowing, while the facial cleansing product with the composition of Example 1 showed virtually no color change, as shown in Figure 5.

[0089] (6) Inhibition of macrophage IL-6 function

[0090] Test Method: Cell Seeding: RAW264.7 cells were seeded at 4000 cells / well in 96-well plates and cultured at 37°C in a 5% CO2 incubator for 24 h. The working solution of the test substance was prepared according to the experimental design. When the cell deposition rate in the 96-well plates reached 80%–90%, 10 mg / ml LPS solution was diluted to 1 μg / ml and added to each well at 50 μL / well. An equal volume of culture medium was added to the blank control group. The plates were then cultured at 37°C in a 5% CO2 incubator for 4 h. Drug administration was performed according to the test protocol, and finally, the IL-6 content in the culture medium was detected using a kit.

[0091] The results are shown in Figure 3. Compared with the negative group, the IL-6 content in the positive group increased significantly, indicating that the stimulation conditions in this experiment were effective. The results show that neither laboratory-prepared high-hardness water nor commercially available facial cleanser + high-hardness water could inhibit IL-6 release, while the addition of Example 1 of this invention to hard water significantly improved hard water stimulation and had a significant inhibitory effect on IL-6 release, demonstrating a mild effect after mitigating the influence of ions.

[0092] (7) Comparative test of human body cleaning with high hardness water

[0093] Test Methods: 30+ volunteers with normal skin, aged 18-40 years (excluding pregnant or breastfeeding women), were recruited. High-hardness water prepared in the laboratory was used. The left and right faces were compared, with the control cleanser (Table 6) and the control cleanser containing Example 1 as shown in the table. Changes in skin condition after cleansing were tested over a 4-week period. Frontal and bilateral 45° oblique photographs of the patients' faces were taken using a VISIA skin analyzer to collect control data. The measurement environment (temperature, humidity, and light source) was kept relatively constant.

[0094] The results are shown in Figure 4. Long-term use of hard water for cleansing leads to the accumulation of minerals on the skin over time, damaging the skin barrier. After using the control cleanser without chelating ability, the facial hemoglobin area significantly increased, increasing threefold compared to the initial value. The cleanser with the addition of Example 1, which removes most ions from hard water, showed a lower increase in hemoglobin, demonstrating an improvement in mitigating the potential risks of hard water and enhancing the gentleness of the cleanser.

[0095] (8) Consumer sensory evaluation test

[0096] Test Methods: To evaluate the skin-feel improvement effect of the composition involved in this invention, which is similar to foam, Example 1, which has a synergistic effect, was added to the cleansing system to prepare a cleansing product, which was then compared and verified with a blank sample. The hard water-resistant composition was applied to the cleansing system. Thirty healthy volunteers were selected for sensory evaluation testing. During the application process, the participants were rated on multiple dimensions, including texture, foam, cleansing power, rinsing speed, dryness, tightness, gentleness, and preference. The score range was 1-9 points (preference was 0-10 points), with higher scores indicating a higher level of acceptance for that dimension. The evaluation criteria are shown in Table 9 below.

[0097] Table 9: Sensory Evaluation Criteria

[0098] The evaluation results are shown in Table 10 below.

[0099] Table 10: Sensory evaluation results of the facial cleansing compositions in the examples and comparative examples

[0100] The cleansing honey prepared in Example 1 of this invention outperformed the commercially available blank cleanser in all evaluation indicators (except for cleansing power), and the volunteers' overall preference was higher. Among them, the foam richness dimension showed the most significant difference between the foam of Example 1 and the control cleanser. This is because adding the cleanser of Example 1 can significantly reduce the hardness of domestic water, increase foam richness and stability, and improve the washing experience, as shown in Figure 6.

[0101] The above description, in conjunction with specific preferred embodiments, provides a further detailed explanation of the present invention. However, it should not be construed that the specific implementation of the present invention is limited to these descriptions. For those skilled in the art, various simple deductions or substitutions can be made without departing from the concept of the present invention, and all such modifications and substitutions should be considered within the scope of protection of the present invention.

Claims

1. A facial cleansing composition resistant to hard water, characterized in that, Including the following parts by weight of raw materials: 0.24-1.5 parts by weight of lauryl hydroxysulfonate betaine Sodium diethyltriaminepentamethylenephosphonate 0.1-0.7 parts by weight Sodium gluconate 0.045-0.3 parts by weight Skin Conditioner A 0.08-1 part by weight Skin Conditioner B 0.01-0.5 parts by weight The skin conditioning agent A is 1,3-propanediol, 1,2-hexanediol and capryloyl hydroxamic acid, and the skin conditioning agent B is glycerin and stevia leaf / stem extract.

2. The hard water-resistant facial cleansing composition according to claim 1, characterized in that, The skin conditioning agent A comprises, by weight, 2-8 parts of capryloyl hydroxamic acid, 20-40 parts of 1,2-hexanediol, and 52-78 parts of 1,3-propanediol.

3. The hard water-resistant facial cleansing composition according to claim 1, characterized in that, The skin conditioning agent B, by weight, comprises 49-61 parts glycerin, 36-46 parts water, and 3-5 parts stevia leaf / stem extract.

4. The hard water-resistant facial cleansing composition according to claim 1, characterized in that, The ingredients include the following parts by weight: 3 parts lauryl hydroxysulfonate betaine, 0.4 parts sodium diethylenetriaminepentamethylenephosphonate, 0.15 parts sodium gluconate, 0.5 parts skin conditioning agent A, and 0.1 parts skin conditioning agent B.

5. The hard water-resistant facial cleansing composition according to claim 1, characterized in that, The preparation method of the skin conditioning B is subcritical fluid extraction.

6. The hard water-resistant facial cleansing composition according to claim 1, characterized in that, The preparation method of the skin conditioning B includes the following steps: Stevia leaves / stems were dried, pulverized using a pulverizer, filtered through a 60-mesh sieve, and dried again. The dried powder was weighed and added to a high-temperature, high-pressure reactor at a liquid-to-material ratio of 1:1 to 1:

5. After stirring evenly, nitrogen gas was introduced to purge the gas. Subcritical water extraction was performed at a pressure of 0.5-3 MPa and a temperature of 70-350℃. After extraction, the subcritical extract was collected and centrifuged at 3000-8000 r / min for 5-15 min. The supernatant was evaporated and concentrated, and then mixed with glycerin to obtain sample skin conditioning agent B.

7. The use of the hard water resistant facial cleansing composition according to any one of claims 1 to 6 in the preparation of cleansing skin care products.

8. A skincare product, characterized in that, The cleansing composition includes any one of claims 1 to 6.

9. The use of the hard water resistant facial cleansing composition according to any one of claims 1 to 6 in the preparation of cosmetics.

10. A cosmetic product, characterized in that, The cleansing composition includes any one of claims 1 to 6.

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