Water-soluble unit for liquid compositions

Abstract

The present invention relates to a water-soluble unit, comprising an agricultural liquid composition, a method of preparation thereof.

Description

[0001] WATER-SOLUBLE UNIT FOR LIQUID COMPOSITIONS

[0002] RELATED APPLICATION

[0003] Throughout this application various publications are referenced. The disclosures of these documents in their entireties are hereby incorporated by reference into this application in order to more fully describe the state of the art to which this invention pertains.

[0004] TECHNICAL FIELD

[0005] The invention refers to a water-soluble unit, comprising an agricultural liquid composition, a method of preparation thereof.

[0006] BACKGROUND

[0007] Liquid agrochemical compositions are well known as being packaged in bottles.

[0008] The composition in bottles requires a manual measuring of the composition, followed by dilution in water. Often the dilution is in a large volume using hard and / or cold water.

[0009] Measuring the composition before dilution is often not conducted in a precise manner which may lead to overdosing or insufficient amount of the active ingredient. In addition, imprecise dosage increases resistance development of plant, fungus and / or insect toward pesticides and may lead to reduction in their efficacy.

[0010] In addition, formulating two or more active ingredients are sometimes very challenging because the active ingredients and / or carriers not completable and there is a need to develop a delivering system for combining the active ingredients.

[0011] In the art, different hands-free, measured packages comprising solid compositions are known. Using a water-soluble unit important for reduce level of waste and substantially reduces carbon footprint by eliminating the contaminated empty.

[0012] Soluble packaging for liquid agricultural composition is challenging.

[0013] There is a need to develop water-soluble package units for agriculture uses.SUMMARY OF THE INVENTION

[0014] The present invention provides a water-soluble unit, comprising an agricultural liquid composition.

[0015] The present invention provides a water-soluble unit, comprising an agricultural liquid composition wherein the volume of the liquid in the unit is from about 100 ml to 2000 ml.

[0016] The present invention provides a water-soluble unit, comprising an agricultural liquid composition wherein the volume of the liquids in the unit is from about 200 ml to 2000 ml.

[0017] The present invention provides a multi chamber water-soluble unit, comprising at least two chambers, wherein at least one chamber comprising an agricultural liquid composition.

[0018] The present invention provides a product comprising a multi chamber water soluble unit comprising at least two compositions.

[0019] In the context of this disclosure, multi chamber refers to more than one chamber.

[0020] The present invention provides a method for combining at least two incompatible active ingredients, the method comprises packaging the at least two active ingredients in at least two chambers of a water-soluble unit, wherein at least one active ingredient is formulated as liquid composition.

[0021] The present invention provides a process for preparing a water-soluble unit comprising an agricultural liquid composition, comprising (1) preparing a water-soluble chamber, (2) adding a agricultural liquid composition and (3) wet sealing of the chamber.

[0022] The present invention provides a process for preparing a multi chamber water soluble unit comprising at least two agricultural compositions comprising (1) preparing at least two water-soluble chambers, (2) adding to each chamber an agricultural composition wherein at least one composition is liquid composition, (3) wet sealing of the chambers, wherein (1) if one of the chamber comprises solid composition it optionally sealed by heating and (2) if the two chambers are separated, addition step of connecting to one unit is conducted .The present invention provides the use of the water-soluble unit described herein for preparing a diluted agricultural composition for controlling pests.BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1. A multi chamber water-soluble unit comprises OD composition of Hum etyl sulforim (180 ml) and EC composition of prothioconazole (120 ml)DESCRIPTION OF SPECIFIC EMBODIMENTS OF THE INVENTION

[0024] Definitions

[0025] Prior to setting forth the present subject matter in detail, it may be helpful to provide definitions of certain terms to be used herein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as is commonly understood by one of skill in the art to which this subject matter pertains. The following definitions are provided for clarity.

[0026] The term “a” or “an” as used herein includes the singular and the plural, unless specifically stated otherwise. Therefore, the terms “a,” “an,” or “at least one” can be used interchangeably in this application.

[0027] As used herein, the term “about” when used in connection with a numerical value includes ±10% from the indicated value. In addition, all ranges directed to the same component or property herein are inclusive of the endpoints, are independently combinable, and include all intermediate points and ranges. It is understood that where a parameter range is provided, all integers within that range, and tenths thereof, are also provided by the invention. For example, “0.1-80%” includes 0.1%, 0.2%, 0.3%, etc. up to 80%.

[0028] As used herein, the term “agricultural composition” means composition comprises an ingredient (agricultural material) used in the practice of farming, including cultivation of the soil for the growing of crops. However, the use of agricultural materials is not limited to application to crops. Agricultural materials is also used in the practice of non-crop uses, it may be applied to any surface, e.g., for the purpose of cleaning or aiding or inhibiting growth of a living organism. Other noncrop applications include, but are not limited to, application to an animal, e.g. livestock, application to turf and ornamentals, and application to railroad weed. Agricultural material can be used in connection with material which is used as additive such as adjuvants (e.g. rainfastness agent) and safeners.

[0029] Examples of agricultural materials, agrochemicals, pesticides, hormones, bio-stimulants, adjuvant, safener and plant growth agents.

[0030] As used herein, the term “agrochemical” is a chemical active ingredient used in the practice of farming, including cultivation of the soil for the growing of crops. However, the use of agrochemicals is not limited to application to crops. Agrochemicals may be applied to any surface, e.g., for the purpose of cleaning or aiding or inhibiting growth of a living organism. Examples of agrochemical, pesticides, hormones, bio-stimulants, and plant growth agents.

[0031] As used herein, the term “pesticide”, “pesticide compound” or “pesticidal compound” means a compound capable of killing or inhibiting growth or proliferation of a pest, whether for plant protection or for non-crop application. As used herein, all terms “pesticide”, “pesticide compound”or “pesticidal compound” fall within “agricultural material”. The term “pesticide”, “pesticide compound” or “pesticidal compound” includes, but is not limited to, insecticide, nematicide, herbicide, fungicide, algicides, animal repellents, and acaricides.

[0032] As used herein, the term “pest” includes, but is not limited to, insect, nematode, weed, fungi, algae, mite, tick, and animal. As used herein, the term “weed” refers to any unwanted vegetation.

[0033] As used herein, the term "water-soluble unit" refers to at least one chamber prepared from a water-soluble film.

[0034] In particular, the term "water-soluble unit" refers to at least one chamber prepared from a water-soluble polymer.

[0035] As used herein, the term "chamber film" refers to the chamber wall.

[0036] Delivering agricultural liquid composition as a water soluble units is challenging due to the high volume of the composition required for preparing spray composition.

[0037] Many parameters affect the stability of a water-soluble unit which comprises at least one agricultural liquid composition in terms of delivery and shelflife.

[0038] The present invention provides a water-soluble unit, comprising an agricultural liquid composition.

[0039] The present invention provides a water-soluble unit comprising a water-soluble film and an agricultural liquid composition.

[0040] The water-soluble unit comprises at least one chamber made from water-soluble film which surrounds the agricultural liquid composition.

[0041] The water-soluble unit is sealed such that the composition does not leak out of the chamber during storage.

[0042] In some embodiments, the unit may comprise two films or more. A first film may be shaped to an open chamber into which the agricultural liquid composition is added. A second film may then be laid over the first film in such an orientation as to close the opening of the chamber.

[0043] The first and second films may then be sealed together along a sealing area.

[0044] In some embodiments, the sealing area comprises sealing film.

[0045] In some embodiments, width of the sealing area of the water-soluble unit comprising a agricultural liquid agricultural composition is about 2-10 mm.In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is about 3-10 mm.

[0046] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is about 4-10 mm.

[0047] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is about 5-10 mm.

[0048] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm or 10 mm.

[0049] In some embodiments, the water-soluble unit comprising a liquid agricultural composition has width sealing area of at least about 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm or 10 mm.

[0050] In some embodiments, the water-soluble unit comprising a liquid agricultural composition has width sealing area of 6 mm, 7mm, 8mm, 9mm, or 10 mm.

[0051] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 6-10 mm. In some embodiments, the water-soluble unit comprising a liquid agricultural composition has sealing area with width of 6-10 mm.

[0052] The water-soluble unit may comprise two, or even three, or even four chambers.

[0053] The present invention provides a water-soluble unit, comprising an agricultural liquid composition wherein the volume of the liquid in the unit is from about 100 ml to 2000 ml.

[0054] The present invention provides a water-soluble unit, comprising an agricultural liquid composition wherein the volume of the liquid in the unit is from about 200 ml to 2000 ml.

[0055] In some embodiments the unit comprises one chamber.

[0056] In some embodiments, the unit comprises at least two connected chambers (multi chamber).

[0057] In some embodiments, the chamber comprises two chamber walls and the chamber is sealed by connecting the two walls.

[0058] In some embodiments, the chamber comprises two chamber walls and sealing film obtained by connecting the two walls.

[0059] The present invention provides a water-soluble unit, comprising an agricultural liquid compositionwherein (1) the unit comprises one or more chambers prepared from a water-soluble film and (2) sealing film obtained by connecting the chamber walls.

[0060] The present invention provides a water-soluble unit, comprising an agricultural liquid composition wherein (1) the unit comprises one or more chambers prepared from a water-soluble film and the chamber comprises two chamber walls and (2) sealing film obtained by connecting the two walls.

[0061] The present invention provides a water-soluble unit, comprising an agricultural liquid composition wherein (1) the unit comprises one or more chambers prepared from a water-soluble film and (2) sealing area.

[0062] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 2-10 mm.

[0063] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 3-10 mm.

[0064] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 4-10 mm.

[0065] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 5-10 mm.

[0066] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm or 10 mm.

[0067] In some embodiments, the water-soluble unit comprising a liquid agricultural composition has width sealing area of at least about 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm or 10 mm.

[0068] In some embodiments, the water-soluble unit comprising a liquid agricultural composition has width sealing area of 6 mm, 7mm, 8mm, 9mm, or 10 mm.

[0069] In some embodiments, width of the sealing area of the water-soluble unit comprising a liquid agricultural composition is at least about 6-10 mm. In some embodiments, the water-soluble unit comprising a liquid agricultural composition has sealing area with width of 6-10 mm.The present invention provides a water-soluble unit, comprising at least two chambers wherein at least one chamber comprises liquid agricultural composition.

[0070] The present invention provides a multi chamber water-soluble unit, comprising at least two chambers, wherein at least one chamber comprising an agricultural liquid composition.

[0071] The present invention provides a water-soluble unit, comprising at least two chambers wherein at least one chamber comprising liquid agricultural composition and wherein the volume of the liquid in the unit is from about 100 ml to 2000 ml.

[0072] The present invention provides a water-soluble unit, comprising at least two chambers wherein at least one chamber comprising liquid agricultural composition and wherein the volume of the liquid in the unit is from about 200 ml to 2000 ml.

[0073] In some embodiments at least one chamber comprises at least 200 ml liquid.

[0074] In some embodiments at least one chamber comprises at least 100 ml liquid.

[0075] In some embodiments at least one chamber comprises at least 100 ml liquid and the total volume of the liquids in the unit is equal or less than 2000 ml.

[0076] In some embodiments at least one chamber comprises at least 200 ml liquid and the total volume of the liquids in the unit is equal or less than 2000 ml.

[0077] The present invention provides a multi chamber water-soluble unit, comprising at least two chambers, wherein at least one chamber comprises an agricultural liquid composition and wherein the volume of the liquid in the unit is from about 200 ml to 2000 ml.

[0078] The present invention provides a product comprising a multi chamber water soluble unit comprising at least two compositions.

[0079] The present invention provides a product comprising a water soluble unit comprising an agricultural liquid composition.

[0080] The present invention provides a product comprising a multi chamber water soluble unit comprising at least two compositions wherein at least one is agricultural liquid composition.The present invention provides a product comprising a multi chamber water soluble unit comprising at least two compositions wherein at least one is agricultural liquid composition and the volume of the liquid is from about 200 ml to 2000 ml.

[0081] The present invention provides a product comprising a multi chamber water soluble unit comprising at least two compositions wherein at least one is agricultural liquid composition and the volume of the liquid is from about 100 ml to 2000 ml.

[0082] The present invention provides a product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions.

[0083] In some embodiments, the total volume of the liquid composition in multi chamber water soluble unit is from 200 ml to 2000 ml.

[0084] In some embodiments, the total volume of the liquid composition in multi chamber water soluble unit is from 100 ml to 2000 ml.

[0085] In some embodiments, when the unit includes at least two chambers, one of the chambers comprising at least 100 ml liquid composition.

[0086] In some embodiments, when the unit includes at least two chambers, one of the chambers comprising at least 200 ml liquid composition.

[0087] In some embodiments, the chamber comprising at least 100 ml liquid composition.

[0088] In some embodiments, the chamber comprising at least 200 ml liquid composition.

[0089] In some embodiments, the agricultural liquid composition is oil dispersion.

[0090] In some embodiments, the agricultural liquid composition is emulsifiable concentrate composition.

[0091] In some embodiments, the agricultural liquid composition is oil dispersion of Hum etyl sulforim. In some embodiments, the agricultural liquid composition is emulsifiable concentrate composition of prothioconazole.

[0092] In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions.

[0093] In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the weight ratio between the two liquids in thetwo chambers are between about 10:1 to 1:10. In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the weight ratio between the two liquids in the two chambers are between about 3 : 1 to 1 :3. In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the weight ratio between the two liquids in the two chambers are between about 2:1 to 1:2. In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the weight ratio between the two liquids in the two chambers is about 1:1.

[0094] In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the volume ratio between the two liquids in the two chambers are between about 10:1 to 1:10. In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the volume ratio between the two liquids in the two chambers are between about 3:1 to 1:3. In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the volume ratio between the two liquids in the two chambers are between about 2: to 1:2. In some embodiments, the product comprising a multi chamber water soluble unit comprising at least two agricultural liquid compositions wherein the volume ratio between the two liquids in the two chambers is about 1:1.

[0095] In some embodiments when the unit comprises two compositions and the fungicides are Hum etyl sulforim and prothioconazole, the weight ratio between Hum etyl sulforim and prothioconazole is about 1 : 10 to 1:1.

[0096] In some embodiments the weight ratio between Hum etyl sulforim and prothioconazole is about 1:1.33

[0097] In some embodiments the weight ratio between Hum etyl sulforim and prothioconazole is about 1:1.5

[0098] In some embodiments the weight ratio between Hum etyl sulforim and prothioconazole is about 1 :2 In some embodiments the weight ratio between Hum etyl sulforim and prothioconazole is about 1:2.66

[0099] In some embodiments when the unit comprises two compositions and the fungicides are fluxapyroxad and flumetylsulforim, the weight ratio between fluxapyroxad and Hum etyl sulforim is about 1:10 to 1:1.

[0100] In some embodiments the weight ratio between fluxapyroxad and flumetylsulforim is about 1:1.33In some embodiments the weight ratio between fluxapyroxad and flumetyl sulforim is about 1:1.2

[0101] In some embodiments, the unit comprises at least two chambers, wherein at least one chamber comprises an agricultural liquid composition and at least one chamber comprises an agricultural solid composition.

[0102] In some embodiments, at least one liquid composition comprises flumetyl sulforim and at least one solid composition comprises phthalimide fungicide

[0103] In some embodiments, phthalimide fungicide is captan

[0104] In some embodiments, phthalimide fungicide is folpet

[0105] In some embodiments when the unit comprises two compositions and the fungicides are flumetyl sulforim and captan, the weight ratio between flumetyl sulforim and captan is about 1 :3 to 1:13.

[0106] In some embodiments when the unit comprises two compositions and the fungicides are flumetyl sulforim and folpet, the weight ratio between flumetyl sulforim and folpet is about 1:5 to 1:27.

[0107] In some embodiments, the agricultural liquid composition is oil dispersion of flumetyl sulforim and the second agricultural liquid composition is emulsifiable concentrate composition of prothioconazole.

[0108] In some embodiments, the water-soluble unit is stable.

[0109] In some embodiments, “stable / stability / stabilization” when used in connection with the unit stability, stability of the unit refers to leakage of the composition out of the chamber before storage and after storage. Storage stability is tested after at least 1 year of storage at temperature up to 30°C or after any standard accelerated storage stability test (e.g. after 8 weeks of storage at a temperature of 40 ± 2 °C, after 12 weeks of storage at a temperature of 35 ± 2 °C, or after 18 weeks of storage at a temperature of 30 ± 2 °C). In some embodiments, stable is wherein no leakage is observed.In some embodiments, when the term "stable / stability" is used in connection with lab conditions, stability is tested based on standards set forth by the Collaborative International Pesticides Analytical Council (CIPAC).(e.g. MT176). The CIPAC is an international, organization that promotes international agreements on methods for the analysis of pesticides and physico-chemical test methods for formulations. Methods adopted by the CIPAC are published in the CIPAC Handbooks, available online at www.CIPAC.org / index.php / methods-publications, the entire content of each method is hereby incorporated by reference into the subject application.

[0110] In some embodiments, width of the sealing film of the water-soluble unit comprising a liquid agricultural composition is at least about 2-10 mm.

[0111] In some embodiments, width of the sealing film of the water-soluble unit comprising a liquid agricultural composition is at least about 3-10 mm.

[0112] In some embodiments, width of the sealing film of the water-soluble unit comprising a liquid agricultural composition is at least about 4-10 mm.

[0113] In some embodiments, width of the sealing film of the water-soluble unit comprising a liquid agricultural composition is at least about 5-10 mm.

[0114] In some embodiments, width of the sealing film of the water-soluble unit comprising a liquid agricultural composition is at least about 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm or 10 mm.

[0115] In some embodiments, the water-soluble unit comprising a liquid agricultural composition has width sealing film of at least about 2 mm, 3 mm, 4 mm, 5 mm, 6 mm, 7 mm, 8 mm, 9 mm or 10 mm.

[0116] In some embodiments, the water-soluble unit comprising a liquid agricultural composition has width sealing film of 6 mm, 7mm, 8mm, 9mm, or 10 mm.

[0117] In some embodiments, width of the sealing film of the water-soluble unit comprising a liquid agricultural composition is at least about 6-10 mm. In some embodiments, the water-soluble unit comprising a liquid agricultural composition has sealing film with width of 6-10 mm.

[0118] In some embodiments, the agricultural liquid composition is oil dispersion composition comprises fungicide.

[0119] In some embodiments, the agricultural liquid composition is emulsifiable concentrate composition comprises fungicide.

[0120] In some embodiments, when the unit is multi chamber, the compositions are oil dispersion composition comprises fungicide, emulsifiable concentrate or any combination thereof.In some embodiments, the agricultural liquid composition is oil dispersion composition and the composition comprising more than one fungicide.

[0121] In some embodiments, the agricultural liquid composition is emulsifiable concentrate composition and the composition comprising more than one fungicide.

[0122] In some embodiments, the liquid composition is based on non-aqueous carrier.

[0123] In some embodiments, the non-aqueous carrier is acetophenone.

[0124] In some embodiments, the non-aqueous carrier is fatty acid alkyl amide such as Genagen In some embodiments, the non-aqueous carrier is CEHL

[0125] In some embodiments, the non-aqueous carrier is alkoxylated vegetable oil such as Ethoxylated Castor Oil (POE 30)

[0126] In some embodiments, the Ethoxylated Castor Oil (POE 30) is Agnique rso 30

[0127] In some embodiments, N-octyl pyrrolidone is Agsolex-8.

[0128] In some embodiments, the organic carrier is aromatic solvent such as solvesso 150

[0129] In some embodiments, the fungicide is Hum etyl sulforim

[0130] In some embodiments, the fungicide is prothioconazole.

[0131] In some embodiments, the fungicide is fluxapyroxad.

[0132] In some embodiments, the agricultural liquid composition is oil dispersion of Hum etyl sulforim and the second composition is solid composition of captan.

[0133] In some embodiments, the agricultural liquid composition is oil dispersion of Hum etyl sulforim and the second composition is solid composition of folpet.

[0134] In some embodiments, the agricultural liquid composition is oil dispersion of Hum etyl sulforim and the second composition is emulsifiable concentrate composition of prothioconazole.

[0135] In some embodiments, the agricultural liquid composition is oil dispersion of Hum etyl sulforim and the second composition is emulsifiable concentrate composition of fluxapyroxad.

[0136] In some embodiments, the water soluble unit is storage at atmospheric pressure. In some embodiments, the water soluble unit is sealed in Protective Bag.

[0137] In some embodiments, the unit is packaged in an external Protective Bag and the Protective Bag is sealed at vacuum.

[0138] In some embodiments, sealed at vacuum refers to pumping the air in the protective bag after placing the water-soluble unit of the present invention.

[0139] In some embodiments, pumping at potency / strength of 0.25 to -0.7 Bar for a duration of 1 to 90 secondsThe present invention provides a method for combining at least two active ingredients which require different type of formulation, the method comprises packaging the at least two active ingredients in at least two chambers of a water-soluble unit, wherein at least one active ingredient is formulated as liquid composition.

[0140] The present invention provides a method for combining at least two incompatible active ingredients, the method comprises packaging the at least two active ingredients in at least two chambers of a water-soluble unit, wherein at least one active ingredient is formulated as liquid composition.

[0141] The present invention provides a method for combining at least two active ingredients as one product wherein at least one of the active ingredients is formulated as liquid composition, the method comprises packaging the at least two active ingredients in at least two chambers of a water-soluble unit, wherein at least one active ingredient is formulated as liquid composition.

[0142] The present invention provides a product comprising a multi chamber water-soluble unit comprising at least two compositions.

[0143] The present invention provides a process for preparing a water-soluble unit comprising a liquid composition, comprising (1) preparing a water-soluble chamber, (2) adding an agricultural liquid composition and (3) sealing of the chamber.

[0144] The present invention provides a process for preparing a water-soluble unit comprising a liquid composition, comprising (1) preparing a water-soluble chamber, (2) adding an agricultural liquid composition and (3) sealing of the chamber with upper film.

[0145] In some embodiments, first film may be shaped to an open chamber into which the agricultural liquid composition is added. A second film may then be laid over the first film in such an orientation as to close the opening of the chamber.

[0146] The first and second films may then be sealed together along a seal area.

[0147] In some embodiments, the seal area comprises sealing film.

[0148] In some embodiments, the sealing of the chamber is conducted by wet sealing

[0149] In some embodiments, the sealing of the chamber is conducted by heat sealing

[0150] In some embodiments, wet sealing is a water welding.

[0151] In some embodiments, sealing of the chamber can be conducted by methods such Hot bar welding, Impulse welding, Ultrasonic welding, Laser welding, Water Welding and PVA glue.The present invention provides a process for preparing a water-soluble unit comprising a liquid composition, comprising (1) preparing a water-soluble chamber, (2) adding a liquid composition and (3) wet sealing of the chamber.

[0152] The present invention provides a process for preparing a multi chamber water soluble unit comprising at least two compositions comprising (1) preparing at least two water-soluble chambers, (2) adding to each chamber an agricultural composition wherein at least one composition is liquid composition, (3) wet sealing of the chambers, wherein (1) if one of the chamber comprises solid composition it optionally sealed by heating (2) if the two chamber are separated, addition step of connecting to one unit is conducted.

[0153] The present invention provides a process for preparing water soluble unit comprising liquid pesticidal composition, process comprises (1) obtaining chamber wall (2) fulfill the liquid composition (3) wet sealing with upper film.

[0154] In some embodiments, upper film used in step 3 is wetted film.

[0155] In some embodiments, the chamber frame / edges are stamped with water stamping.

[0156] In some embodiments, the chamber frame / edges are stamped with water stamping at temperature of 20-25 C.

[0157] In some embodiments, the chamber edges are wetted using water diluted PVA (solution).

[0158] The present invention provides the use of the water-soluble unit described herein for preparing a diluted agricultural composition for controlling pests.

[0159] In some embodiments, the filing and sealing the chamber is by using Flat bad or drum filling. In some embodiments, the water-soluble unit comprises at least one agricultural liquid composition, is packaged in an external Protective Bag.

[0160] In some embodiments, the protective Bag is sealed at vacuum.

[0161] In some embodiments, sealed at vacuum refers to pumping the air in the protective bag after placing the water-soluble unit of the present invention.

[0162] In some embodiments, pumping at potency / strength of 0.25 to -0.7 Bar for a duration of 1 to 90 seconds

[0163]

[0164] The agricultural liquid composition of the present invention is a non-aqueous based composition. In some embodiments, the non-aqueous based composition is oil dispersion.

[0165] In some embodiments, the non-aqueous based composition is emulsifiable concentrate.In some embodiments, the agricultural liquid composition is oil dispersion composition and the agricultural is fungicide.

[0166] In some embodiments, the agricultural liquid composition is emulsifiable concentrate composition and the agricultural is fungicide.

[0167] In some embodiments, the agricultural liquid composition is oil dispersion composition comprises at least one fungicide.

[0168] In some embodiments, the agricultural liquid composition is emulsifiable concentrate composition comprises at least one fungicide.

[0169] In some embodiments, the agricultural liquid composition is oil dispersion composition and the composition comprises more than one fungicide.

[0170] In some embodiments, the agricultural liquid composition is emulsifiable concentrate composition and the composition comprising more than one fungicide.

[0171] In some embodiments, the liquid composition is based on non-aqueous carrier.

[0172] In some embodiments, the non-aqueous carrier Acetophenone

[0173] In some embodiments, the non-aqueous carrier is fatty acid alkyl amide such as Genagen In some embodiments, the non-aqueous carrier is CEHL.

[0174] In some embodiments, the non-aqueous carrier is alkoxylated vegetable oil such as ethoxylated castor oil (POE 30)

[0175] In some embodiments, Ethoxylated Castor Oil (POE 30) is Agnique rso 30

[0176] In some embodiments, the non-aqueous carrier N-alkyl pyrrolidone such as N-Octyl pyrrolidone. In some embodiments, the non-aqueous carrier is aromatic solvent such as solvesso 150.

[0177] In some embodiments, the fungicide is azole fungicide

[0178] In some embodiments, the fungicide is strobilurin fungicide

[0179] In some embodiments, the fungicide is SDHI fungicide

[0180] In some embodiments, the fungicide is flumetylsuforim

[0181] In some embodiments, the fungicide is prothioconazole.

[0182] In some embodiments, the fungicide is fluxapyroxad.

[0183] In some embodiments, the at least one fungicide is flumetylsuforim

[0184] In some embodiments, the at least one fungicide is prothioconazole.

[0185] In some embodiments, the at least one fungicide is fluxapyroxad.

[0186] In some embodiments, the at least one of the fungicide is mancozeb.In some embodiments, the fungicide is at least one of group of azole fungicide, SDHI fungicide, mancozeb and flumetyl sulforim.

[0187] In some embodiments, fungicide is the azole fungicide, SDHI fungicide, mancozeb, flumetyl sulforim or any combination thereof.

[0188] In some embodiments, the liquid composition is as described in WO 2021 / 044371.

[0189] In some embodiments, the liquid composition is as described in WO 2017 / 203527.

[0190] In some embodiments, the agricultural liquid composition is oil dispersion of flumetyl sulforim and the second composition is solid composition of captan.

[0191] In some embodiments, the agricultural liquid composition is oil dispersion of flumetyl sulforim and the second composition is solid composition of folpet.

[0192] In some embodiments, the agricultural liquid composition is oil dispersion of flumetyl sulforim and the second composition is emulsifiable concentrate composition of prothioconazole.

[0193] In some embodiments, the agricultural liquid composition is oil dispersion of flumetyl sulforim and the second composition is emulsifiable concentrate composition of fluxapyroxad.

[0194] In some embodiments, the agricultural liquid composition has a viscosity of at least 500 cP. In some embodiments, the composition has a viscosity of 500 cP - 3000 cP. In some embodiments, the agricultural liquid composition has a viscosity of 500 cP - 2500 cP. In some embodiments, the composition has a viscosity of 800 cP - 3000 cP. In some embodiments, the agricultural liquid composition has a viscosity of 1600 cP - 2200 cP. In some embodiments, the agricultural liquid composition has a viscosity of equal to or less than 3000 cP.

[0195] In some embodiments, the agricultural liquid composition has a viscosity of about 500 cP - 1000 cP. In some embodiments, the agricultural liquid composition has a viscosity of about 1000 cP -1500 cP. In some embodiments, the agricultural liquid composition has a viscosity of about 1500 cP - 2000 cP. In some embodiments, the agricultural liquid composition has a viscosity of about 2000 cP - 2500 cP. In some embodiments, the agricultural liquid composition has a viscosity of about 2500 cP - 3000 cP.

[0196] In some embodiments, the agricultural liquid composition has a viscosity of about 500 cP, about 600 cP, about 700 cP, about 800 cP, about 900 cP, about 1000 cP, about 1100 cP, about 1200 cP, about 1300 cP, about 1400 cP, about 1500 cP, about 1600 cP, about 1700 cP, about 1800 cP, about 1900 cP about 2000 cP, about 2100 cP, about 2200 cP, about 2300 cP, about 2400 cP about 2500 cP, about 2600 cP, about 2700 cP, about 2800 cP, about 2900 cP, about 3000 cP.In some embodiments, the agricultural liquid composition is an oil dispersion (OD) composition. In some embodiments, the agricultural liquid composition is an emusifiable concentrate (EC) composition.

[0197] In some embodiments, the agricultural liquid composition comprises a non-aqueous liquid carrier and the non-aqueous composition has a viscosity of at least 500 cP. In some embodiments, the agricultural liquid composition comprises a non-aqueous liquid carrier and the non-aqueous composition has a viscosity of equal to or less than 3000 cP.

[0198] In some embodiments, the agricultural liquid composition is an oil dispersion (OD) composition and the OD composition has a viscosity of at least 500 cP. In some embodiments, the agricultural liquid composition is an oil dispersion (OD) composition and the OD composition has a viscosity of 500 cP - 2500 cP. In some embodiments, the agricultural liquid composition is an oil dispersion (OD) composition and the OD composition has a viscosity of equal to or less than 2500 cP.

[0199] Viscosity may be measured using Collaborative International Pesticides Analytical Council (CIPAC) MT192 - viscosity of liquids by rotational viscometer, the entire content of which is hereby incorporated by reference into this application. When viscosity is described in the subject application, the viscosity is measured using CIPAC MT192 using spindle 62 at 12 rpm or spindle 63 at 12 rpm.

[0200] In some embodiments, viscosity is measured using spindle 62 at 12 rpm. In some embodiments, viscosity is measured using spindle 63 at 12 rpm. In some embodiments, the composition has a viscosity of at least 500 cP when measured using CIPAC MT192 using spindle 62 at 12 rpm or using spindle 63 at 12 rpm. In some embodiments, the composition has a viscosity of 500 cP -3000 cP when measured using CIPAC MT 192 using spindle 62 at 12 rpm or using spindle 63 at 12 rpm. In some embodiments, the composition has a viscosity of 500 cP - 2500 cP when measured using CIPAC MT192 using spindle 62 at 12 rpm or using spindle 63 at 12 rpm. In some embodiments, the composition has a viscosity of 800 cP - 3000 cP when measured using CIPAC MT192 using spindle 62 at 12 rpm or using spindle 63 at 12 rpm. In some embodiments, the composition has a viscosity of 1600 cP - 2200 cP when measured using CIPAC MT192 using spindle 62 at 12 rpm or using spindle 63 at 12 rpm. In some embodiments, the composition has a viscosity of equal to or less than 3000 cP when measured using CIPAC MT192 using spindle 62 at 12 rpm or using spindle 63 at 12 rpm.In some embodiments, the total amount of non-aqueous carrier in the agricultural liquid composition ranges from about 30 to about 80% by weight based on the total weight of the composition. In some embodiments, the total amount of non-aqueous carrier in the agricultural liquid agricultural liquid composition ranges from about 40% to about 70% by weight based on the total weight of the composition. In some embodiments, the total amount of non-aqueous carrier in the agricultural liquid composition is about 50% by weight based on the total weight of the composition.

[0201] In some embodiments, the total amount of non-aqueous carrier in the OD composition ranges from about 30 to about 80% by weight based on the total weight of the composition. In some embodiments, the total amount of non-aqueous carrier in the OD composition ranges from about 40% to about 70% by weight based on the total weight of the composition. In some embodiments, the total amount of non-aqueous carrier in the OD composition is about 50% by weight based on the total weight of the composition.

[0202] In some embodiments, the total amount of non-aqueous carrier in the EC composition ranges from about 30 to about 80% by weight based on the total weight of the composition. In some embodiments, the total amount of non-aqueous carrier in the EC composition ranges from about 40% to about 70% by weight based on the total weight of the composition. In some embodiments, the total amount of non-aqueous carrier in the EC composition ranges from about 40% to about 80% by weight based on the total weight of the composition. In some embodiments, the total amount of non-aqueous carrier in the EC composition is about 80% by weight based on the total weight of the composition.

[0203] In some embodiments, the concentration of the pesticide in the agricultural liquid composition is 20 g / L to 850 g / L.

[0204] In some embodiments, the concentration of the pesticide in the agricultural liquid composition is 50 g / L to 750 g / L. In some embodiments, the concentration of the pesticide in the agricultural liquid composition is 150 g / L to 750 g / L. In some embodiments, the concentration of the pesticide in the agricultural liquid composition is 300 g / L to 750 g / L. In some embodiments, the concentration of the pesticide in the agricultural liquid composition is 250 g / L.

[0205] In some embodiments, the concentration of pesticide in the agricultural liquid composition is greater than 5% by weight based on the total weight of the agricultural liquid composition. In some embodiments, the concentration of pesticide in the composition is greater than 10% by weightbased on the total weight of the composition. In some embodiments, the concentration of c pesticide in the agricultural liquid composition is greater than 25% by weight based on the total weight of the agricultural liquid composition. In some embodiments, the concentration of pesticide in the agricultural liquid composition is greater than 50% by weight based on the total weight of the agricultural liquid composition.

[0206] In some embodiments, the agricultural liquid composition has a water content of less than 6% by weight based on the total weight of the composition. In some embodiments, the agricultural liquid composition has a water content of less than 1% by weight based on the total weight of the composition.

[0207] In some embodiments, the agricultural liquid composition has a water content of less than 0.5% by weight based on the total weight of the composition.

[0208] In some embodiments, the present invention provides a water-soluble unit, comprising an agricultural liquid composition, wherein the agricultural liquid composition is an oil dispersion composition comprising flumetyl sulforim.

[0209] In some embodiments, the present invention provides a multi chamber water-soluble unit, comprising an agricultural liquid composition, wherein in one chamber the agricultural liquid composition is an oil dispersion composition comprising flumetyl sulforim and in the second chamber the agricultural liquid composition is an emulsifiable concentrate composition comprising prothioconazole.

[0210] In some embodiments, the present invention provides a multi chamber water-soluble unit, comprising an agricultural liquid composition, wherein in one chamber the agricultural liquid composition is an oil dispersion composition comprising flumetyl sulforim and in the second chamber the agricultural liquid composition is an emulsifiable concentrate composition comprising fluxapyroxad.

[0211] In some embodiments, the present invention provides a multi chamber water-soluble unit, comprising an agricultural liquid composition, wherein in one chamber the agricultural liquid composition is an oil dispersion composition comprising flumetyl sulforim and in the second chamber the agricultural liquid composition is a solid composition comprising folpet.

[0212] In some embodiments, the present invention provides a multi chamber water-soluble unit, comprising an agricultural liquid composition, wherein in one chamber the agricultural liquid composition is an oil dispersion composition comprising flumetyl sulforim and in the second chamber the agricultural liquid composition is a solid composition comprising captan.

[0213] In some embodiments, the liquid volume in the unit is from 200ml to 2000ml.In some embodiments, the liquid volume in the chamber is from 100 ml to 2000ml.

[0214] CHAMBER FILM

[0215] The chamber film is selected based on compatibility testing with the relevant Agrochemical that is to be packed. Another key factor for selecting the PVA is the water temperature in which the POD is anticipated to be used.

[0216] The chamber which comprises at least one agricultural material is prepared from a water-soluble film.

[0217] Compatibility testing include accelerated long-term exposure of film and specific product including but not limited to testing of long-term storage stability, freeze and defrosting testing, light exposure etc.

[0218] In some embodiments, the water-soluble film is prepared using a water-soluble polymer.

[0219] In some embodiments, the water-soluble unit which comprises at least one agricultural material is prepared from water-soluble polymer.

[0220] In some embodiments, the water-soluble film is polyvinyl alcohol based polymer.

[0221] In some embodiments, the water-soluble film is polyvinyl alcohol.

[0222] In some embodiments, the water-soluble polymer is polyvinyl alcohol based polymer.

[0223] In some embodiments, the water-soluble polymer is polyvinyl alcohol.

[0224] In some embodiments, the chamber film is polyvinyl alcohol based polymer.

[0225] In some embodiments, the chamber film is polyvinyl alcohol.

[0226] In some embodiments, poly vinyl alcohol based polymer is a modified polymer.

[0227] In some embodiments, the poly vinyl alcohol based polymer is manufactured by Aicello.

[0228] In some embodiments the polyvinyl alcohol polymer is Aicello PT 40, Aicello PT 80 (manufactured by Aicello).

[0229] In some embodiments the polyvinyl alcohol polymer is Aicello Solublon GA#75 B.

[0230] In some embodiments the polyvinyl alcohol polymer is Aicello Solublon GS#75 BTX.

[0231] In some embodiments, the chamber can be prepared by methods such as vacuum forming, Vertical Form Fill & Seal (VFFS), Horizontal Form Fill & Seal (HFFS) or any other type of FFS, or Flow Pack.

[0232] In some embodiments, the sealing of the chamber is conducted by wet sealing

[0233] In some embodiments, the sealing of the chamber is conducted by heat sealing

[0234] In some embodiments, wet sealing is a water welding.In some embodiments, sealing of the chamber can be conducted by methods such Hot bar welding, Impulse welding, Ultrasonic welding, Laser welding, Water Welding and PVA glue.

[0235] In some embodiments, when additional to the liquid composition, the unit comprises a chamber comprises a solid composition, the sealing of the chamber comprises solid composition can be conducted by methods such as impulse welding, ultrasonic welding, water sealing.

[0236] In some embodiments, the heating sealing is conducted by VFFS machine.

[0237] STABILITY PARAMETERS

[0238] Stabilizing water-soluble unit which comprises at least one liquid agricultural composition, refers to leakage of the liquid from the chamber. In some embodiments, the water-soluble unit is stable wherein more than 99% of the units are observed with no leakage.

[0239] In some embodiments, the water-soluble unit is stable wherein no leakage is observed. In addition stability of the liquid composition is measure according to CIPAC , Increasing of stability may be measured by, but not limited to, changes of the dissolution time of the soluble unit, change of sieve residual of the soluble unit, change of elasticity of the chamber film of the water-soluble unit, change in the volume of the water-soluble unit and / or sinking level and / or sinking speed of water-soluble unit in the tank sprayer.

[0240] Dissolution time refers to time to initiate the dissolution of the chamber film and / or time for complete dissolution of the chamber film. Shelflife refers to the period where the water-soluble unit which comprises at least one agricultural material, maintains its properties in term of the dissolution time of the chamber film, of sieve residual of the chamber film, elasticity of the chamber film of the water-soluble unit which comprises at least one agricultural material,, the volume of the water-soluble unit which comprises at least one agricultural material, and / or the sinking level of water-soluble unit which comprises at least one agricultural material, in a tank sprayer.

[0241] The method for sealing the water-soluble unit comprising a pesticidal liquid composition disclosed in the present invention, increases the shelf life of the water-soluble unit which comprises at least one agricultural material by at least 1 month, 6 months, 12 months.

[0242] The width of sealing the water-soluble unit comprising a pesticidal liquid composition disclosed in the present invention, increases the shelflife of the water-soluble unit which comprises at least one agricultural material by at least 1 month, 6 months, 12 months.

[0243] In some embodiments, stability is measured by dissolution time.

[0244] In some embodiments, the elasticity of the chamber film is measured.In some embodiments, elasticity refers but is not limited to brittle level.

[0245] In some embodiments, the brittle level is tested by a tensile test device according to ISO 527, ASTM D638.

[0246] In some embodiments, brittle level is measured by testing the physical properties of the chamber film, such as weight comparison.

[0247] In some embodiments, the brittle level is tested by drop-test according to the UN demands for specific specimens of products from the "Orange Book".

[0248] UN demands for specific specimens of products from the "Orange Book" such as UN recommendation on the transport of dangerous goods, part 6 (edition 17, 2011) (orange book), ICAO Technical Instructions for the safe transport of Dangerous goods by air, edition 2011-2012, IMO IMDG CODE, 2010, amendment 35-10.

[0249] Protective Bag

[0250] In some embodiments, the water-soluble unit which comprises at least one agricultural liquid composition is placed in a Protective Bag prepared by a known method for preparation.

[0251] Known method refers but is not limited to Vertical Form Fill and Seal (VFFS).

[0252] In some embodiments, the material which is used for packaging the water-soluble unit which comprises at least one agricultural material under vacuum includes any material which preserves the vacuum for at least 6 months.

[0253] In some embodiments, the vacuum is preserved for at least 12 months, 18 months, or 24 months. In some embodiments, the Protective Bag is prepared from a non-biodegradable material. In some embodiments, the Protective Bag is prepared from a biodegradable material. In some embodiments, the Protective Bag is prepared from a recycled material.

[0254] In some embodiments, the Protective Bag is prepared from a poly ethylene based polymer.

[0255] In some embodiments, the poly ethylene based polymer is a cross linked poly ethylene based polymer.

[0256] In some embodiments, the Protective Bag is prepared from a cross linked poly ethylene based polymer

[0257] In some embodiments, the Protective Bag is based on aluminium foil.

[0258] In some embodiments, the Protective Bag is based on paper foil.

[0259] In some embodiments the Protective Bag is a water-soluble paper.

[0260] In some embodiments, the Protective Bag is prepared from a multi-layer based material.In some embodiments, the Protective Bag is single layer, double layer, triple layer and / or ternary layers.

[0261] In some embodiments, the Protective Bag is prepared from an aluminum foil based material. In some embodiments, the Protective Bag is a Laminated 3 layers foil PE / AL / PET.

[0262] In some embodiments, the Protective Bag is a Laminated double layer foil PE / PET.

[0263] In some embodiments, a Bio-degradable Protective Bag is corn starch based.

[0264] In some embodiments, the Protective Bag is prepared by a known method for preparation.

[0265] Known method refers but is not limited to Vertical Form Fill and Seal (VFFS).

[0266] WATER-SOLUBLE UNIT CHARACTERIZATION / PROPERTIES

[0267] The water-soluble unit which comprises at least one chamber and at least one agricultural material wherein the unit is prepared from a soluble film and an agricultural material is enclosed within the chamber that unit has critical parameters for efficiency in the field.

[0268] Critical parameters such as thickness of the chamber, elasticity of the chamber, and chamber film dissolution time.

[0269] In some embodiments, dissolution time refers to the time needed for full dissolution of the chamber film at 5°C water temperature which is about 10 minutes in filed / tank sprayer simulation conditions.

[0270] In some embodiments, dissolution time refers to the time needed for full dissolution of the chamber film at 5°C to 25°C water temperature which is less than 10, less than 9, less than 8, minutes in filed / tank sprayer simulation conditions.

[0271] In some embodiments, dissolution time refers to time for initiating the dissolution of the chamber film at 5°C to 25°C water temperature which is less than 5 minutes, less than 4 minutes, in filed / tank sprayer simulation conditions.

[0272] In some embodiments, the thickness of the chamber film comprising an agricultural composition is between 30 -150 microns.

[0273] In some embodiments, the thickness of the chamber film comprising an agricultural composition is between 60-120 microns.

[0274] AGRICULTURAL MATERIAL

[0275] Agriculture material may refer to agricultural composition.

[0276] In some embodiments, agriculture material may refer to agrichemical composition. In some embodiments, the agriculture composition is solid composition and / or liquid composition. In some embodiments, the agrichemical composition is solid composition and / or liquid composition. Insome embodiments, the agricultural composition is a concentrated composition. In some embodiments, concentrated composition refers to the composition in the water -soluble unit before wetting the water -soluble unit with water.

[0277] In some embodiments, the agricultural composition comprises at least one disintegration agent. In some embodiments, the disintegration agent is a blooming agent, an effervescence system or a combination thereof.

[0278] In some embodiments, the effervescent system comprises a mixture of an acid and a base, preferably a weak acid and a weak base. However, the effervescent system that may be used with the composition is not limited to the combination of an acid and a base.

[0279] Chemical reaction between an acid and a base can result in a rapid spontaneous evolution of CO2 gas when the effervescent system is combined with and wetted by water. In-situ formation of gas enhances solid disintegration and / or particles dispersion.

[0280] Acids may include, but are not limited to, organic and inorganic acids. The inorganic acid may be a weak acid. Organic acids may include but are not limited to carboxylic acids such as citric acid, fumaric acid, phthalic acid, maleic acid, malic acid, oxalic acid, adipic acid, glutaric acid, 2-methyl glutaric acid, succinic acid and tartaric acid or any combination thereof.

[0281] Bases may include, but are not limited to, organic and inorganic bases. The inorganic base may be a weak base. Inorganic base may include but are not limited to an alkali metal carbonate or bicarbonate such as lithium carbonate, sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate or any combination thereof.

[0282] Agriculture material refers but is not limited to agrochemical, biological material, natural material, adjuvants and safener.

[0283] Agrochemical refers but is not limited to pesticide, bio stimulant, growth regulator, fertilizer / nutrients.

[0284] In some embodiments, the agrochemical is a pesticide.

[0285] In some embodiments, the pesticide is an insecticide. In some embodiments, the pesticide is a fungicide. In some embodiments, the pesticide is an acaricide. In some embodiments, the pesticide is a nematicide. In some embodiments, the pesticide is an herbicide.

[0286] Composition prepared from the water soluble unit

[0287] The present invention provides a water diluted agricultural composition comprising any one of the water-soluble unit described herein and water.

[0288] In some embodiments, the water -soluble unit is wetted after removing the Protective Bag.1

[0289] In some embodiments, the Protective Bag is removed prior to the wetting of the water-soluble unit with water.

[0290] METHOD OF USE

[0291] The present invention also provides a method of controlling and preventing pest comprising:

[0292] (1) preparing a water diluted agricultural composition from any one of the water-soluble unit / product described herein and

[0293] (2) applying the water diluted agricultural composition to a locus where the pest is to be controlled and prevented.

[0294] The present invention also provides a method of controlling and preventing pest comprising:

[0295] (1) preparing a water diluted agricultural composition from any one of the water-soluble unit / product described herein and

[0296] (2) applying the water diluted agricultural composition to at least one of a plant, an area adjacent to a plant, soil adapted to support growth of a plant, a root of a plant, foliage of a plant, and / or a seed adapted to produce a plant.

[0297] The present invention also provides a method of controlling and preventing pest comprising:

[0298] (1) preparing a water diluted agricultural composition from any one of the water-soluble unit / product described herein and

[0299] (2) applying the water diluted agricultural composition of any one of the packaging, Protective Bag and / or water-soluble unit described herein to an area infested with the unwanted pest so as to thereby control the unwanted pest.

[0300] The present invention also provides a method of controlling and preventing pest comprising:

[0301] (1) preparing a water diluted agricultural composition from any one of the water-soluble unit / product described herein and

[0302] (2) contacting a plant, a locus thereof or propagation material thereof with water diluted agricultural composition of any one of water-soluble unit / product described herein so as to thereby control the plant disease.

[0303] In some embodiments, the water diluted agricultural composition prepared from any one of water-soluble / product unit described herein is prepared by wetting the water-soluble unit with water.

[0304] In some embodiments, when there is Protective Bag, wetting is after removing the Protective Bag.

[0305] In some embodiments, when there is Protective Bag, wetting is by adding to water, the water-soluble unit after removing the Protective Bag.In some embodiments, when there is Protective Bag, wetting is by placing the water-soluble unit after removing the Protective Bag, on the spray tank top sieve and / or in the side inductors and adding water on over the unit.

[0306] In some embodiments, when there is Protective Bag, the water diluted agricultural composition prepared from any one of water-soluble unit / product described herein is prepared by adding to water the water-soluble unit after removing the Protective Bag.

[0307] In some embodiments, when there is Protective Bag, the water diluted agricultural composition prepared from any one of the water-soluble unit / product described herein is prepared by placing the water-soluble unit after removing the Protective Bag, on the spray tank top sieve and / or in the side inductors and adding water on over the unit.

[0308] In some embodiments, when there is Protective Bag, wetting is by placing the water-soluble unit after removing the Protective Bag, in side inductors or in external filling stations and adding water on over the unit.

[0309] In some embodiments, diluted agricultural composition is water diluted agricultural composition. In one embodiment, the pest is insect. In one embodiment, the pest is fungi. In one embodiment, the pest is nematode. In one embodiment, the pest is weed.

[0310] In one embodiment, the locus is a plant, an area adjacent to a plant, soil adapted to support growth of a plant, a root of a plant, foliage of a plant, and / or a seed adapted to produce a plant.

[0311] In one embodiment, the locus is skin of an animal or surrounding of an animal. In one embodiment, the locus is a railway or an area surrounding a railway.

[0312] The water diluted agricultural composition prepared from any one of the packaging, Protective Bag and / or water-soluble unit described herein may be applied to healthy or diseased plant. In some embodiments, the water diluted agricultural composition prepared from any one of the packaging, Protective Bag and / or water-soluble unit described herein is applied to various plants including but not limited to crops, seeds, bulbs, propagation material, turf, or ornamental species. Each embodiment disclosed herein is contemplated as being applicable to each of the other disclosed embodiments. Thus, all combinations of the various elements described herein are within the scope of the invention.

[0313] The invention is illustrated by the following examples without limiting it thereby.

[0314] EXPERIMENTS SECTION

[0315] Process for Forming Filling and Sealing of liquid non-Aqueous Agrochemical into PVA chamber.

[0316] Materials:Chamber film: Aicello Solublon GA#75 B; GS#75 BTX

[0317] Oil dispersion formulation comprising flumetyl sulforim exemplified in WO2021224802.

[0318] <

[0319]

[0320] Emulsifiable concentrate comprising prothioconazole, exemplified in WO2021152509.

[0321] &

[0322]

[0323] Equipment

[0324] • Vacuum forming filling station that includes heating, humidifying and water / liquid stamping access + pressure exerting plate.

[0325] • Round or Elliptical Pod forming Mold with specific curvature radius edges up to 0.2r and vacuum forming holes with a diameter preferably lower than 0.5mm.

[0326] • 6-10 mm silicon or rubber or rubber + silicone O ring elevating bands.

[0327] • Micro Fiber Stamping device

[0328] • Stretching frame for top PVA layer.

[0329] Working process:

[0330] 1. Mold is preheated to 80-90 degrees centigrade.

[0331] 2. First layer of the specific PVA film is laid on top of the specified mold. Film is placed in room temperature and in an environment that has less than 40% RH.

[0332] 3. The Silicon or rubber O ring is inserted into slots at the peripheries of the mold or the chamber to be filled. This O ring is used to create elevated edges of the later vacuum formed mold.

[0333] 4. Vacuum at level of 2-6 bar is exerted through the holes in of the pre-shaped mold on the first layer of PVA.

[0334] 5. Liquid composition is filled into chamber.6. Water (room temperature) stamping or diluted PVA solution (solution in water) is set on the elevated peripheries edges of the chamber. The process in done in unified pressure around the entire edge of the mold and is completed in less than 5 seconds.

[0335] 7. Top layer of framed and streached PVA is placed on top of the filled vacuum formed cavity.

[0336] 8. heated 80-90 degrees centigrade top plate is pushed down at pressure of 4-6 bar for a minimal duration of 30 seconds on the formed unit to allow full adhesion of the two PVA layers.

[0337] 9. 10- 30 seconds Curing time is given for the unpressed yet vacuumed formed unit

[0338] 10. Vacuum of the bottom layer of PVA is released and unit is taken out from the mold. Multi chamber water soluble unit comprising OD composition and of EC composition is obtained as exemplified in Figure 1.

[0339] Stability tests for the water soluble unit of figure 1 :

[0340] (1) leakage of liquid from the unit

[0341] No observation of leakage liquid from the unit

[0342] (2) coloring and sweating of sealing area / film

[0343] No observation of coloring of the sealing area and / or "sweating" of sealing lines

[0344] (3) Dissolution time of the unit

[0345] Initial dissolution time (seconds to 2 min) in cold water 5 degrees centigrade.

[0346] Full dissolution time (up to 10 min) in cold water 5 degrees centigrade.

[0347] (4) Stability and sieves residual after storage at 40°C temperature for 8 weeks

[0348] No observation of leakage liquid from the unit

[0349] No observation of coloring of the sealing area and / or "sweating" of sealing lines

[0350] Initial dissolution time (seconds to 2 min) in cold water 5 degrees centigrade.

[0351] Full dissolution time (up to 10 min) in cold water 5 degrees centigrade.

[0352] After 30 min, no PVA film residues over the sieves was observed.

Claims

WHAT IS CLAIMED IS:

1. A water-soluble unit, comprising an agricultural liquid composition.

2. A water-soluble unit, comprising an agricultural liquid compositionwherein (1) the unit comprises one or more chambers prepared from a water-soluble film and (2) sealing film obtained by connecting the chamber walls.

3. The unit of claim 1 or 2, wherein the wherein (1) the volume of the composition is from about 100 ml to 2000 ml or (2) the volume of the composition is from about 200 ml to 2000 ml.

4. A water-soluble unit, comprising an agricultural liquid composition wherein the volume of the composition is from about 200 ml to 2000 ml.

5. A water-soluble unit, comprising at least two chambers wherein at least one chamber comprising liquid an agricultural composition.

6. The unit of any one of claims 1-5, wherein the agricultural liquid composition is oil dispersion composition comprises fungicide.

7. The unit of any one of claims 1-5, wherein the agricultural liquid composition is emulsifiable concentrate composition comprises fungicide.

8. The unit of any one of claims 2-5, wherein the unit is multi chamber, the compositions are oil dispersion composition, emulsifiable concentrate or any combination thereof.

9. The unit of any one of claims 1-8, wherein the agricultural liquid composition is oil dispersion composition and the composition comprises more than one fungicide.

10. The unit of any one of claims 1-8, wherein the agricultural liquid composition is emulsifiable concentrate composition and the composition comprises more than one fungicide.

11. The unit of claims 9 or 10, wherein the fungicide is at least one of azole fungicide, SDHI fungicide, mancozeb and Hum etyl sulforim.

12. The unit of claims 9 or 10, wherein the fungicide is azole fungicide, SDHI fungicide, mancozeb, Hum etyl sulforim or any combination thereof.

13. A method for combining at least two active ingredients which required different type of formulation, the method comprises packaging the at least two active ingredients in at least twochambers of a water-soluble unit, wherein at least one active ingredient is formulated as liquid composition.

14. A method for combining at least two active ingredients as one product wherein at least one of the active ingredients is formulated as liquid composition, the method comprises packaging the at least two active ingredients in at least two chambers of a water-soluble unit, wherein at least one active ingredient is formulated as liquid composition.

15. A method for combining at least two incompatible active ingredients, the method comprises packaging the at least two active ingredients in at least two chambers of a water soluble unit.

16. A product comprising a multi chamber water soluble unit comprising at least two compositions wherein at least one is agricultural liquid composition.

17. A product comprising a water soluble unit comprising an agricultural liquid composition.

18. A process for preparing a water soluble unit comprising a liquid composition, comprising (1) preparing a water-soluble chamber, (2) adding a liquid composition and (3) wet sealing of the chamber.

19. A process for preparing a multi chamber water soluble unit comprising at least two compositions comprising (1) preparing at least two water-soluble chambers, (2) adding to each chamber an agricultural composition wherein at least one composition is liquid composition, (3) wet sealing of the chambers, wherein (1) if one of the chamber comprises solid composition it optionally sealed by heating (2) if the two chamber are separated, addition step of connecting to one unit is conducted.

20. Use of the water-soluble unit described herein for preparing a diluted agricultural composition for controlling pests.

21. The water-soluble unit of any one of claims 1-9, further sealed in Protective Bag.

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