Pharmaceutical composition for controlling distant metastasis comprising lactobacillus sakei CVL-001 as active ingredient
The Lactobacillus sakei CVL-001 strain addresses the limitations of current metastatic cancer treatments by inhibiting metastasis through immune regulation, offering a safe and effective solution for controlling distant cancer spread.
WO2026155376A1PCT designated stage Publication Date: 2026-07-23IND FOUND OF CHONNAM NAT UNIV
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Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- IND FOUND OF CHONNAM NAT UNIV
- Filing Date
- 2025-12-04
- Publication Date
- 2026-07-23
AI Technical Summary
Technical Problem
Current treatments for metastatic cancer, such as chemotherapy and immunotherapy, have significant side effects and limitations, and there is a need for a safer, more effective method to inhibit and prevent cancer metastasis.
Method used
A pharmaceutical and food composition utilizing the Lactobacillus sakei CVL-001 strain as an active ingredient, which has been shown to inhibit metastasis in animal models by regulating the immune system and reducing lung metastasis.
Benefits of technology
The Lactobacillus sakei CVL-001 strain effectively reduces the number and area of lung metastases in mouse models, providing a safe and effective means to control, inhibit, or treat distant cancer metastasis with minimal side effects.
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Abstract
The present invention relates to a composition for inhibiting cancer metastasis, comprising, as an active ingredient, a Lactobacillus sakei CVL-001 strain isolated from kimchi. The composition according to the present invention exhibits an excellent effect of inhibiting lung metastasis in a mouse model in which lung metastasis has been induced by injecting melanoma and breast cancer, and thus can be used as a pharmaceutical composition and food composition for inhibiting distant metastasis, which can be safely used in the human body without toxicity and side effects.
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