Nebulization apparatus

Abstract

A nebulization apparatus, comprising: a container assembly (1), comprising a container (11) and a sealing plug (12), the container (11) having a first end (111) and a second end (112); and a piston assembly (2), comprising a piston rod (21), a first piston (22), and a second piston (23). In an accommodating cavity of the container (11), a first chamber (31) is formed on the side of the second piston (23) facing away from the sealing plug (12), and a second chamber (32) is formed between the second piston (23) and the sealing plug (12). The first chamber (31) is used for accommodating a first raw material, and the second chamber (32) is used for accommodating a second raw material. When the piston rod (21) pushes the first piston (22) to move relative to the second piston (23) in a first direction, the first raw material enters the second chamber (32) and is mixed with the second raw material to form a mixed material, and the sealing plug (12) is detached from the first end (111).

Description

atomizing device

[0001] Related applications

[0002] This application claims priority to Chinese patent application filed on January 23, 2025, with application number CN202510104785.5 and entitled “Atomizing Device”, the entire contents of which are incorporated herein by reference. Technical Field

[0003] This application relates to the field of inhalation equipment technology, and in particular to an atomizing device. Background Technology

[0004] Nanobodies, with their small molecular weight, stable structure, and strong tolerability, are suitable for developing various drug delivery routes, including intravenous injection, subcutaneous administration, oral administration, and nebulized inhalation. Inhalation of nanobodies can avoid the first-pass effect of oral administration, demonstrating good efficacy in the treatment of lung diseases and showing great promise for applications in the treatment of respiratory and pulmonary diseases.

[0005] Lyophilized powder is a common storage method for nanobodies. The powdered drug is stored in a vial, and sterile water is added to reconstitute it to obtain a reconstituted solution, which is then used for drug administration.

[0006] When administering medication using existing nebulizers, the reconstituted solution must first be added to the air compressor or vibratory nebulizer. The nebulizer converts the antibody drug into a fine mist or aerosol particles of appropriate size. The particle size distribution after nebulization directly affects subsequent inhalation and therapeutic efficacy. This nebulization inhalation method has the following disadvantages:

[0007] (1) The medication process is complicated. Users need to first reconstitute the powdered medicine with sterile water, then add the reconstituted solution to the nebulizer, and then perform nebulization inhalation. In addition, the reconstituted solution will come into direct contact with the air during the process of adding it to the nebulizer. Due to the introduction of new air, there is a risk of contamination.

[0008] (2) Air compression or vibration nebulizers are large in size and complex in structure. For small doses of medication, the medication is wasted, which affects the treatment effect.

[0009] (3) The physicochemical properties of nanobody drugs are relatively complex. When they are delivered through existing air compression or vibration nebulization devices, the drug must be able to withstand the high pressure and force output by the nebulization device and maintain the integrity of the drug structure and bioactivity during delivery. Summary of the Invention

[0010] In view of this, the present application provides an atomizing device to solve at least one problem existing in the background art. The device has a simple and compact structure, is easy to carry, requires few preparation steps, and is easy to operate. For small-dose atomization work, it can reduce the waste of mixed materials and make the dosage more accurate. For drugs with relatively complex physicochemical properties, it can maintain the integrity of the drug structure and the drug's biological activity during delivery.

[0011] Therefore, this application provides the following technical solution.

[0012] This application provides an atomizing device, the atomizing device comprising:

[0013] A container assembly comprising a container and a sealing plug, the container having an open first end and a second end, the sealing plug being used to seal the first end;

[0014] A piston assembly includes a piston rod, a first piston, and a second piston, wherein the first piston and the second piston are sequentially disposed in the container along a first direction, and one end of the piston rod is located in the container and is linked to the first piston.

[0015] In the container cavity, the side of the second piston facing away from the sealing plug forms a first chamber, and the second piston and the sealing plug form a second chamber; the first chamber is used to contain a first raw material, and the second chamber is used to contain a second raw material;

[0016] When the piston rod pushes the first piston to move relative to the second piston in a first direction, the first raw material enters the second chamber and mixes with the second raw material to form a mixture, and in this process, the sealing plug is dislodged from the first end under the pressure of the mixture.

[0017] Optionally, during the process of assembling the piston rod into the container, the piston rod pushes the first piston to move relative to the second piston in a first direction, so that the first raw material enters the second chamber.

[0018] Optionally, when the first piston moves in the first direction to abut against the second piston, the first raw material completely enters the second chamber.

[0019] Optionally, the first raw material is in liquid form, and the second raw material is in freeze-dried powder or liquid form.

[0020] Optionally, the second raw material is a lyophilized powder nanobody.

[0021] Optionally, the sealing plug is a rubber plug.

[0022] Optionally, the inner wall of the container is provided with a groove, which forms a communicating flow channel with the outer wall of the second piston, and the first chamber and the second chamber are connected through the communicating flow channel;

[0023] Under the compression of the first piston or the action of the air pressure in the first chamber, the first raw material enters the second chamber through the connecting channel.

[0024] Optionally, the atomizing device further includes an atomizing chip located outside the sealing plug;

[0025] When the hydraulic pressure of the liquid flowing out from the first end reaches a preset value, the liquid is processed by the atomizing chip to form atomized fine particles and then escapes.

[0026] Optionally, the sealing plug is disposed in the port of the first end and the two are interference-fitted.

[0027] Optionally, when the sealing plug detaches from the first end, the sealing plug abuts against the atomizing chip under the compression of the mixture.

[0028] Optionally, the sealing plug includes a sealing plug body and a plurality of protruding structures, the protruding structures being disposed on the side of the sealing plug body facing the atomizing chip;

[0029] When the sealing plug detaches from the first end, the protruding structure forms a first gap between the sealing plug body and the atomizing chip, through which the mixture in the second chamber flows to the atomizing channel of the atomizing chip.

[0030] Optionally, the atomizing device further includes a pen holder, which has a first hollow column and a second hollow column connected sequentially along a first direction; the container assembly and the piston assembly are both disposed in the pen holder, and the atomizing chip is installed in the second hollow column;

[0031] When the sealing plug detaches from the first end, the sealing plug body is located in the first hollow column, and a second gap is formed between the circumferential surface wall of the sealing plug body and the inner wall of the first hollow column. The second chamber, the second gap, the first gap and the atomizing channel are connected in sequence.

[0032] Optionally, the lateral space dimension of the first hollow column is larger than that of the second hollow column; when the sealing plug is detached from the first end, the protruding structure abuts against the end face of the second hollow column to reduce or completely avoid the protruding structure covering the atomizing channel.

[0033] Optionally, the sealing plug body includes a first column and a second column connected sequentially along a first direction;

[0034] The first column is frustum-shaped and gradually expands along the first direction;

[0035] The second column is cylindrical, and its outer diameter is greater than or equal to the maximum outer diameter of the first column; when the sealing plug is assembled in the port of the first end, the outer wall of the second column is interference-fitted with the inner wall of the first end.

[0036] Optionally, the protruding structure protrudes partially outward from the circumferential surface of the second column;

[0037] When the sealing plug is fitted into the port of the first end, the protruding structure is squeezed and deformed by the inner wall of the first end.

[0038] Optionally, the atomizing device further includes a pen cap, which is connected to the first end of the pen holder;

[0039] The pen cap is provided with a sealing post, which is inserted into the second hollow post and the two are interference-fitted to seal the first end of the pen barrel.

[0040] Optionally, the atomizing device further includes a pen cap connected to the second end of the pen barrel to seal the second end of the pen barrel.

[0041] Optionally, the atomizing device further includes a retainer for holding the container, which is mounted in the pen holder.

[0042] Optionally, the atomizing device further includes a pen holder and a trigger assembly, wherein both the container assembly and the piston assembly are disposed within the pen holder; the trigger assembly includes:

[0043] An operating mechanism is movably mounted on the pen holder;

[0044] A pawl, rotatably connected to the operating mechanism, is used to engage with a ratchet structure provided on the piston rod;

[0045] When the operating mechanism moves along the first direction under external force, the pawl pushes the ratchet structure to make the piston rod move along the first direction, and the piston rod pushes the first piston and the second piston to move to trigger atomization;

[0046] When the operating mechanism moves in the second direction, the piston rod does not move with it, and the first direction is opposite to the second direction.

[0047] Optionally, the operating mechanism is provided with a limiting structure to limit the rotation angle of the pawl, so that the pawl can maintain engagement with the ratchet structure during the movement of the operating mechanism in the first direction.

[0048] Optionally, the operating mechanism includes:

[0049] An operating element, which is at least partially located outside the pen holder;

[0050] An adapter element is located inside the pen holder and connected to the operating element, and the pawl is rotatably connected to the adapter element.

[0051] Optionally, the atomizing device further includes a pen cap, which is connected to the second end of the pen barrel to seal the second end of the pen barrel;

[0052] The pen cap is provided with a limiting groove, and the piston rod is provided with a limiting protrusion; the limiting groove and the limiting protrusion are engaged to restrict the piston rod from rotating relative to the pen cap.

[0053] Optionally, the pen cap is further provided with a receiving groove; when the atomizing device is in the initial state, the ratchet structure is partially located in the receiving groove.

[0054] Optionally, the atomizing device further includes a pen cap, which is connected to the first end of the pen holder;

[0055] When assembling the atomizing device, the piston rod is assembled with the first piston and then pre-assembled with the pen cap to form a first pre-assembled assembly; the pen barrel and the pen cap are assembled and then pre-assembled with the container assembly to form a second pre-assembled assembly; then, the first pre-assembled assembly and the second pre-assembled assembly are assembled, and when the two are assembled, the pawl engages with the ratchet structure.

[0056] This application has the following technical advantages:

[0057] This application provides an nebulizer device. By configuring a first piston and a second piston within a container, forming a first chamber and a second chamber respectively, the device can hold a first raw material and a second raw material. When the user needs to use the nebulizer, the piston rod drives the first piston to move, causing the first raw material to move into the second chamber and mix with the second raw material, thus achieving mixing. No manual operation by the user is required to mix the two raw materials, reducing preparation steps and simplifying the operation. No new air is introduced during the mixing process, reducing the risk of contamination. The nebulizer device has a simple and compact structure, making it easy to carry. For small-dose nebulization, it reduces waste of the mixed materials and provides more accurate dosage. Furthermore, the nebulizer device of this solution uses the piston rod to provide power for nebulization, resulting in lower pressure output to the mixed materials. For drugs with relatively complex physicochemical properties, this helps maintain the integrity of the drug's structure and biological activity during delivery.

[0058] Details of one or more embodiments of this application are set forth in the following drawings and description. Other features, objects, and advantages of this application will become apparent from the specification, drawings, and claims. Attached Figure Description

[0059] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings:

[0060] Figure 1 is a cross-sectional view of the atomizing device of this application in the non-atomizing state;

[0061] Figure 2 is a cross-sectional view of the container assembly, the first piston, and the second piston of this application when assembled;

[0062] Figure 3 is an enlarged view of point A in Figure 1;

[0063] Figure 4 is a cross-sectional view of the atomizing device of this application during a single atomization process;

[0064] Figure 5 is a cross-sectional view of the atomizing device of this application at the end of one atomization cycle;

[0065] Figure 6 is an exploded view of the atomizing device of this application;

[0066] Figure 7 is a three-dimensional structural schematic diagram of the sealing plug of this application (Figure 1);

[0067] Figure 8 is a three-dimensional structural schematic diagram of the sealing plug of this application (Figure 2);

[0068] Figure 9 is a three-dimensional structural diagram of the piston rod of this application;

[0069] Figure 10 is a three-dimensional structural diagram of the pen cap of this application;

[0070] Figure 11 is a three-dimensional structural diagram of the pen holder of this application;

[0071] Figure 12 is a three-dimensional structural diagram of the pen cap of this application;

[0072] Figure 13 is a three-dimensional structural diagram of the atomizing device of this application.

[0073] Explanation of reference numerals in the attached drawings: 100, atomizing device; 1, container assembly; 11, container; 111, first end; 112, second end; 113, groove; 12, sealing plug; 121, sealing plug body; 1211, first column; 1212, second column; 122, protruding structure; 13, bottle cap; 2, piston assembly; 21, piston rod; 211, ratchet structure; 212, limiting protrusion; 213, snap-fit ​​part; 22, first piston; 221, snap-fit ​​groove; 23, second piston; 31, first chamber; 32, second chamber; 4, atomizing chip; 41, atomizing channel; 51, first gap; 52, second gap; 61, pen holder; 611, first hollow column; 612, second hollow column; 6121, end face; 613, snap-fit ​​protrusion; 614. External thread; 615. Long hole; 616. Mounting hole; 62. Pen cap; 621. Sealing post; 622. Snap groove; 623. Sliding groove; 63. Pen cap; 631. Limiting groove; 632. Receiving groove; 633. Internal thread; 7. Retaining element; 8. Trigger assembly; 81. Operating mechanism; 811. Operating element; 8111. Connecting block; 812. Adapter element; 8121. Limiting structure; 82. Pawl; 83. Pivot shaft; 9. Viewing window. Detailed Implementation

[0074] To make the objectives, technical solutions, and advantages of this application clearer, the technical solutions of this application will be clearly and completely described below in conjunction with specific embodiments and corresponding drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0075] The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the scope of this application. When used herein, the singular forms “a,” “an,” and “the” may also be intended to include the plural forms unless the context clearly indicates otherwise. It should also be understood that the term “comprising,” when used in this specification, identifies the presence of the stated features, integers, steps, operations, elements, and / or components, but does not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups. When used herein, the term “and / or” includes any and all combinations of the associated listed items.

[0076] It should be understood that when a structure is referred to as "connected to" or "coupled to" other structures, it may be directly connected to or coupled to other structures, or there may be intervening structures. Conversely, when a structure is referred to as "directly connected to" or "directly coupled to" other structures, there are no intervening structures. It should be understood that although the terms first, second, third, etc., may be used to describe various elements, components, areas, layers, and / or portions, these elements, components, areas, layers, and / or portions should not be limited by these terms. These terms are merely used to distinguish one from another. Therefore, without departing from the teachings of this application, the first element, component, area, layer, or portion discussed below may be referred to as a second element, component, area, layer, or portion. And the discussion of a second element, component, area, layer, or portion does not imply that the first element, component, area, layer, or portion necessarily exists in this application.

[0077] The terms "first direction a" and "second direction b" used in this application refer to the markings in Figures 1 and 2.

[0078] The atomizing device of this application is described in detail below with reference to Figures 1 to 13.

[0079] In this embodiment, as shown in Figures 1 and 2, the atomizing device 100 includes a container assembly 1 and a piston assembly 2. The container assembly 1 includes a container 11 and a sealing plug 12. The container 11 (e.g., a cartridge bottle) has an open first end 111 and a second end 112. The sealing plug 12 is used to seal the first end 111. After the container 11 and the sealing plug 12 are assembled, they can be used to hold raw materials. The piston assembly 2 includes a piston rod 21, a first piston 22, and a second piston 23. The first piston 22 and the second piston 23 are sequentially arranged in the container 11 along a first direction a. One end of the piston rod 21 is located in the container 11 and is linked with the first piston 22.

[0080] When the second piston 23 is assembled into the container 11, a first chamber 31 is formed on the side of the second piston 23 facing away from the sealing plug 12 within the cavity of the container 11, and a second chamber 32 is formed between the second piston 23 and the sealing plug 12. The first chamber 31 is used to contain the first raw material, and the second chamber 32 is used to contain the second raw material. When the piston rod 21 pushes the first piston 22 to move relative to the second piston 23 in the container 11 along the first direction a, the first raw material enters the second chamber 32 under the compression of the first piston 22 or under the action of the air pressure in the first chamber 31 and mixes with the second raw material to form a mixture. Furthermore, during the process of the first raw material entering the second chamber 32 or when the first raw material has completely entered the second chamber 32, the sealing plug 12 is dislodged from the first end 111 under the compression of the mixture. After the first and second raw materials are mixed, the user can use the atomizing device for inhalation. Atomization can be achieved by pushing the first piston 22 and the second piston 23 with the piston rod 21.

[0081] It should be understood that since the first piston 22 and the second piston 23 need to be inserted into the second end 112 of the container 11, the opening of the second end 112 is relatively large, resulting in a gap between the inner wall of the second end 112 of the container 11 and the piston rod 21. Therefore, before the first chamber 31 is sealed by the first piston 22, care should be taken to place the second end 112 of the container 11 upwards to prevent the first material in the first chamber 31 from spilling out from the second end 112. When the first piston 22 is inserted into the container 11, the placement direction of the container 11 is not restricted. Of course, a plug can also be provided at the second end 112 of the container 11 to prevent the first material in the first chamber 31 from spilling out from the second end 112, and the placement direction of the container 11 is not restricted. When the piston rod 21 needs to be installed, the plug can be removed.

[0082] In the above technical solution, by configuring a first piston 22 and a second piston 23 in the container 11, forming a first chamber 31 and a second chamber 32, the first raw material and the second raw material can be respectively contained. When the user needs to use the nebulizer, the first piston 22 is first driven to move relative to the second piston 23 by the piston rod 21, which can cause the first raw material to move into the second chamber 32 and mix with the second raw material, thus achieving the mixing of the two raw materials. Then, the user can use the nebulizer 100 for nebulized inhalation. Compared with the technical solutions of the prior art that use air compression or vibration nebulizers, this solution does not require the user to manually operate to mix the two raw materials, has fewer preparation steps, simplifies the operation steps, and does not introduce new air during the mixing of the first and second raw materials, reducing the risk of contamination. In addition, the nebulizer of this solution has a simple and compact structure, is easy to carry, and can reduce the waste of mixed materials (such as liquid medicine) for small-dose nebulization work, and the dosage is more accurate. In addition, the nebulizer in this solution is powered by the piston rod 21 to achieve nebulization, and the pressure output to the mixture is relatively small. For drugs with relatively complex physicochemical properties (such as nanobody drugs), the drug maintains its complete structure and biological activity during delivery.

[0083] In one embodiment, as shown in Figures 1 and 2, during the assembly of piston rod 21 into container 11, piston rod 21 pushes first piston 22 to move relative to second piston 23 along a first direction a, so that the first raw material enters the second chamber 32. That is, during the assembly of atomizing device 100, the mixing of the first and second raw materials is completed, making operation convenient. Regarding the linkage between piston rod 21 and first piston 22, it can be that first piston 22 is first linked with piston rod 21, and then first piston 22, together with piston rod 21, is assembled into container 11. In this way, during the insertion of piston rod 21 and first piston 22 into container 11, the first raw material in the first chamber 31 moves to the second chamber 32. Alternatively, first piston 22 can be inserted into container 11, and then piston rod 21 can be inserted into container 11, with piston rod 21 completing linkage with first piston 22 during insertion.

[0084] In one embodiment, as shown in Figures 1, 2, 6, and 9, one end of the piston rod 21 is provided with a locking portion 213, and the first piston 22 is provided with a locking groove 221. The locking portion 213 and the locking groove 221 are engaged with each other to link the piston rod 21 and the first piston 22 together. When assembling the atomizing device 100, the piston rod 21 and the first piston 22 are assembled first, and then assembled with the container 11.

[0085] In one embodiment, as shown in Figures 1 and 2, when the first piston 22 moves along the first direction a to abut against the second piston 23, the first raw material completely enters the second chamber 32. Thus, when atomization is required, the piston rod 21 pushes the first piston 22 along the first direction a, immediately pushing the second piston 23 to move synchronously, thereby achieving rapid atomization. Alternatively, when the first raw material completely enters the second chamber 32, a gap can remain between the first piston 22 and the second piston 23. This allows the piston rod 21 to push the first piston 22 along the first direction a until it contacts the second piston 23, and then push the second piston 23 to move synchronously.

[0086] In one embodiment, the first raw material is in liquid form, which may be a drug solution or sterile water for injection, and the second raw material is in lyophilized powder or liquid form. The first raw material in liquid form can more easily flow from the first chamber 31 into the second chamber 32.

[0087] Furthermore, the second raw material is a lyophilized powder nanobody. Currently, the nebulization supply method for nanobodies mainly uses air compression or vibration nebulizers, or inhalation in the form of dry powder. The nebulizer in this solution is used for the nebulization of lyophilized powder nanobodies. Compared with air compression or vibration nebulizers, it has fewer preparation steps, simplifies operation, reduces the risk of contamination, and provides more accurate dosage. It also maintains the integrity of the drug's structure and bioactivity during delivery. Compared with inhalation in the form of dry powder, the nebulizer in this solution atomizes fine particles for inhalation, resulting in a lower flow rate and greater comfort.

[0088] In one embodiment, the sealing plug 12 is a rubber plug, which has a simple structure, good sealing performance, and elasticity.

[0089] In one embodiment, as shown in FIG2, the inner wall of container 11 is provided with grooves 113, and a connecting channel is formed between the grooves 113 and the outer wall of the second piston 23. The first chamber 31 and the second chamber 32 are connected through the connecting channel. Under the compression of the first piston 22 or under the action of the air pressure in the first chamber 31, the first raw material enters the second chamber 32 through the connecting channel. The number of grooves 113 can be one or more. Optionally, to accelerate the mixing speed of the first and second raw materials, the number of grooves 113 is at least two. Furthermore, to facilitate the uniform movement of the first raw material to the second chamber 32, thereby promoting uniform mixing of the first and second raw materials, all grooves 113 are evenly spaced along the circumference of container 11. In addition, to reduce the existence of dead corners on the inner wall of container 11, the inner wall of container 11 is cylindrical.

[0090] In one embodiment, as shown in Figures 1 and 3, the atomizing device 100 further includes an atomizing chip 4. The atomizing chip 4 is provided with multiple atomizing channels 41. The atomizing chip 4 is located outside the sealing plug 12. When the hydraulic pressure of the liquid flowing out of the first end 111 reaches a preset value, the liquid is processed by the atomizing chip 4 to form atomized fine particles and then escapes. In this way, during the mixing process of the first raw material and the second raw material, if the sealing plug 12 is dislodged from the first end 111, since the hydraulic pressure in the second chamber 32 has not reached the preset value at this time, the liquid cannot pass through the atomizing channels 41 of the atomizing chip 4, so as to avoid atomization during the mixing of raw materials and thus material waste.

[0091] Furthermore, as shown in Figure 2, the sealing plug 12 is disposed in the port of the first end 111, and the sealing plug 12 is interference-fitted with the inner wall of the first end 111 to ensure sealing.

[0092] Furthermore, as shown in Figures 2 and 3, when the sealing plug 12 is disengaged from the first end 111, the sealing plug 12 abuts against the atomizing chip 4 under the compression of the mixture.

[0093] In one embodiment, as shown in Figures 3, 7, and 8, the sealing plug 12 includes a sealing plug body 121 and four protruding structures 122, with the protruding structures 122 located on the side of the sealing plug body 121 facing the atomizing chip 4. As shown in Figures 1 and 3, when the sealing plug 12 detaches from the first end 111, the protruding structures 122 create a first gap 51 between the sealing plug body 121 and the atomizing chip 4, preventing the sealing plug body 121 from covering the atomizing channel 41 of the atomizing chip 4. This ensures that the mixture in the second chamber 32 can flow smoothly through the first gap 51 to the atomizing channel 41 of the atomizing chip 4 for successful atomization. Of course, the number of protruding structures 122 can also be one, two, three, or even more.

[0094] Further, as shown in Figures 1, 3, 6, and 13, the atomizing device 100 also includes a pen holder 61 for the user to hold. The container assembly 1 and the piston assembly 2 are both housed within the pen holder 61. The pen holder 61 has a first hollow column 611 and a second hollow column 612 connected sequentially along a first direction a. The atomizing chip 4 is installed in the second hollow column 612. As shown in Figure 3, when the sealing plug 12 is disengaged from the first end 111, the sealing plug body 121 is located in the first hollow column 611. A second gap 52 is formed between the circumferential surface wall of the sealing plug body 121 and the inner wall of the first hollow column 611. The second chamber 32, the second gap 52, the first gap 51, and the atomizing channel 41 are sequentially connected. Thus, during atomization, the mixture in the second chamber 32 flows sequentially through the second gap 52 and the first gap 51 to the atomizing channel 41, achieving atomization. In addition, the second hollow column 612 of this solution can also be used with a mouthpiece assembly (not shown in the figure) for users to inhale through their mouth or nose, so that more atomized fine particles can be delivered to the human body, avoiding waste caused by excessive exposure of atomized fine particles.

[0095] Furthermore, as shown in Figure 3, the lateral space dimension of the first hollow column 611 is larger than that of the second hollow column 612. When the sealing plug 12 is detached from the first end 111, the protruding structure 122 abuts against the end face 6121 of the second hollow column 612 facing the first hollow column 611, so as to reduce or avoid direct contact between the protruding structure 122 and the surface of the atomizing chip 4. That is, it can reduce or completely avoid the coverage of the atomizing channel 41 by the protruding structure 122 and avoid the protruding structure 122 interfering with the atomization operation.

[0096] In one embodiment, as shown in Figures 7 and 8, the sealing plug body 121 includes a first column 1211 and a second column 1212 connected sequentially along a first direction a. The first column 1211 is frustum-shaped and gradually expands along the first direction a. The second column 1212 is cylindrical, and its outer diameter is equal to the maximum outer diameter of the first column 1211. This ensures a smooth transition at the connection between the first column 1211 and the second column 1212. Of course, the outer diameter of the second column 1212 can also be larger than the maximum outer diameter of the first column 1211. As shown in Figures 2 and 7, when the sealing plug 12 is assembled into the port of the first end 111, the outer wall of the second column 1212 is press-fitted with the inner wall of the first end 111. As shown in Figures 3 and 7, when the sealing plug 12 is disengaged from the first end 111, the circumferential outer wall of the first column 1211 is inclined, which is beneficial to improve the flow of the mixture in the second chamber 32 into the second gap 52, thereby accelerating the atomization speed.

[0097] Furthermore, as shown in Figures 7 and 8, the protruding structure 122 partially protrudes outward from the circumferential surface of the second column 1212, which helps to increase the lateral dimension of the protruding structure 122. As shown in Figure 3, this increases the contact area between the protruding structure 122 and the end face 6121 of the first hollow column 611. As shown in Figure 2, when the sealing plug 12 is assembled into the port of the first end 111, the protruding structure 122 is squeezed and deformed by the inner wall of the first end 111 to ensure that the sealing plug 12 can be smoothly engaged in the first end 111 of the container 11.

[0098] In one embodiment, since the mixture will come into contact with the sealing plug 12 during the atomization process of the atomizing device 100, in order to ensure the hygiene and safety of atomized inhalation, as shown in FIG2, the container assembly 1 also includes a bottle cap 13. The bottle cap 13 is placed on the first end 111 of the container 11 to cover the sealing plug 12, so as to prevent the sealing plug 12 from being contaminated during the storage or transportation of the container assembly 1. Before the container assembly 1 needs to be assembled into the pen holder 61, the bottle cap 13 is removed first, and then the assembly is carried out.

[0099] In one embodiment, as shown in Figures 1, 6, and 13, the atomizing device 100 further includes a pen cap 62, which is connected to the first end of the pen barrel 61. As shown in Figures 1 and 3, the pen cap 62 has a sealing post 621, which is inserted into the second hollow post 612 and the two are press-fitted together to seal the first end of the pen barrel 61. When the atomizing device 100 is not in use, the pen cap 62 seals the first end of the pen barrel 61 to prevent the atomizing chip 4 from being contaminated. When the atomizing device 100 needs to be used, the pen cap 62 can be removed.

[0100] Specifically, the connection between the pen cap 62 and the pen holder 61 includes, but is not limited to, snap-fit ​​connection, magnetic connection, or screw connection. In one specific method, as shown in Figures 11 and 12, the pen cap 62 is provided with two snap-fit ​​grooves 622, which are symmetrically distributed. The outer wall of the first end of the pen holder 61 is provided with two snap-fit ​​protrusions 613, which are corresponding to the snap-fit ​​grooves 622. The pen cap 62 is fitted onto the outer periphery of the first end of the pen holder 61 and is snapped into place by the snap-fit ​​protrusions 613 and the snap-fit ​​grooves 622, so as to achieve a detachable connection between the two. Furthermore, to reduce the difficulty of fastening the protrusion 613 and the groove 622, the inner wall of the pen cap 62 is provided with two sliding grooves 623. The sliding grooves 623 and the grooves 622 are arranged one-to-one. The matching sliding grooves 623 and the grooves 622 are arranged sequentially along the circumference of the pen cap 62 and are interconnected. When assembling the pen cap 62 and the pen holder 61, first insert the protrusion 613 into the corresponding sliding groove 623, and then rotate the pen cap 62 or rotate the pen holder 61 so that the protrusion 613 and the groove 622 are fastened together. In this way, the pen cap 62 and the pen holder 61 can be easily fastened together. Of course, the number of protrusions 613, grooves 622 and sliding grooves 623 is not limited to two. There can be three, four or even more, as long as the three are arranged one-to-one.

[0101] Furthermore, as shown in Figures 1, 6 and 13, the atomizing device 100 also includes a pen cap 63, which is connected to the second end of the pen barrel 61 to seal the second end of the pen barrel 61. The pen cap 63, the pen barrel 61 and the pen cap 62 together constitute the outer contour structure of the atomizing device 100.

[0102] Specifically, the connection between the pen cap 63 and the pen barrel 61 includes, but is not limited to, screw connection, snap connection or magnetic connection. In one specific embodiment, as shown in Figures 10 and 11, the inner wall of the pen cap 63 is provided with an internal thread 633, and the outer wall of the second end of the pen barrel 61 is provided with an external thread 614. The pen cap 63 and the pen barrel 61 are connected by screwing the internal thread 633 and the external thread 614, and the sealing performance is good.

[0103] In one embodiment, as shown in Figures 6, 11, and 13, the pen holder 61 is further provided with a mounting hole 616, and the atomizing device 100 also includes a viewing window 9, which is made of transparent plastic or transparent glass. The viewing window 9 is installed in the mounting hole 616 and is positioned opposite to the container 11 to check the remaining amount of the mixture in the container 11. When the mixture in the container 11 is used up, the pen cap 63 can be removed first, and the container 11 can be taken out by pulling the piston rod 21. The pen holder 61 can be inverted, and the sealing plug 12 can be taken out. Then, the piston rod 21 can be separated from the container 11, and the container assembly 1 can be replaced to realize the reuse of the atomizing device 100, save on usage costs, and is simple to operate.

[0104] In one embodiment, as shown in Figures 1 and 6, the atomizing device 100 further includes a retainer 7, which is cylindrical in shape and serves to hold the container 11 to prevent it from rotating. The retainer 7 is installed within the pen holder 61. Compared to directly assembling the container 11 to the pen holder 61, this design reduces the processing requirements on the pen holder 61. Specifically, the outer wall of the retainer 7 is interference-fitted with the inner wall of the pen holder 61, and the inner wall of the retainer 7 is interference-fitted with the outer wall of the container 11 to secure the container 11.

[0105] Furthermore, as shown in Figure 1, the dimension of the retainer 7 in the first direction a is smaller than the dimension of the container 11 in the first direction a, which is beneficial to the lightweight design of the atomizing device 100. Even further, when the second end 112 of the container 11 is placed upwards, the retainer 7 is located at the lower part of the pen holder 61, which is beneficial to the stability of the center of gravity of the atomizing device 100.

[0106] In one embodiment, as shown in Figures 1 and 6, the atomizing device 100 further includes a triggering component 8, which includes an operating mechanism 81 and a pawl 82. The operating mechanism 81 is movably mounted on the pen holder 61, and the pawl 82 is rotatably connected to the operating mechanism 81. The piston rod 21 is provided with a ratchet structure 211, which has a plurality of teeth arranged sequentially along the axial direction of the piston rod 21. The pawl 82 is used to engage with the ratchet structure 211 provided on the piston rod 21.

[0107] As shown in Figures 1, 4, and 5, when the operating mechanism 81 moves along the first direction a under external force, the pawl 82 pushes the ratchet structure 211, causing the piston rod 21 to move along the first direction a. The piston rod 21 then pushes the first piston 22 and the second piston 23 to move, triggering atomization. In other words, the user can trigger atomization through the operating mechanism 81, making operation convenient. When the operating mechanism 81 moves along the second direction b, the piston rod 21 does not move accordingly. The first direction a and the second direction b are opposite, representing two opposite directions along the axial direction of the piston rod 21. In this way, the single-path length of the operating mechanism 81 does not need to be set too large. When the operating mechanism 81 moves to the limit position of the single-path along the first direction a, one atomization is achieved. At this time, the operating mechanism 81 can no longer move along the first direction a. Then, the operating mechanism 81 can be driven to move along the second direction b to reset. At this time, the pawl 82 engages with another tooth of the ratchet structure 211, and the pawl 82 can continue to drive the piston rod 21 to move along the first direction a to achieve the next atomization. After the atomizing device 100 is reused multiple times, all or as much as possible of the mixture in the container 11 can be used up.

[0108] Furthermore, as shown in Figure 1, the operating mechanism 81 is provided with a limiting structure 8121. The limiting structure 8121 is located at the end of the pawl 82 facing away from the container 11. In this way, when the pawl 82 moves along the first direction a, the pawl 82 can stably engage with the ratchet structure 211 under the abutment of the limiting structure 8121. The limiting structure 8121 is used to limit the rotation angle of the pawl 82 so that when the operating mechanism 81 moves along the first direction a under external force, the pawl 82 can maintain engagement with the ratchet structure 211.

[0109] In one embodiment, as shown in Figures 1, 6, and 13, the operating mechanism 81 includes an operating element 811 and a connecting element 812. The operating element 811 is at least partially located outside the pen holder 61 for user operation. The connecting element 812 is located inside the pen holder 61 and connected to the operating element 811. A pawl 82 is rotatably connected to the connecting element 812 via a pivot shaft 83. Optionally, the operating element 811 is a push button, which has a simple structure; the user can trigger atomization by pushing the operating element 811.

[0110] Specifically, as shown in Figures 1 and 11, the operating element 811 is provided with a connecting block 8111, and the pen holder 61 is provided with an elongated hole 615. The connecting block 8111 passes through the elongated hole 615 and extends into the pen holder 61. The connecting block 8111 is connected to the adapter element 812 so that the operating element 811 and the adapter element 812 can move synchronously. In addition, the wall of the elongated hole 615 can restrict the movement direction of the connecting block 8111 to ensure that the operating element 811 can only move along the first direction a or the second direction b.

[0111] In one embodiment, as shown in Figures 9 and 10, the pen cap 63 is provided with a limiting groove 631, and the piston rod 21 is provided with a limiting protrusion 212. The limiting groove 631 and the limiting protrusion 212 are engaged to restrict the piston rod 21 from rotating relative to the pen cap 63. In this way, the piston rod 21 can only move along the first direction a.

[0112] Furthermore, as shown in Figures 1, 9, and 10, the pen cap 63 is also provided with a receiving groove 632. When the atomizing device 100 is in the initial state, some teeth of the ratchet structure 211 are located in the receiving groove 632. In this way, the piston rod 21 can be provided with as many teeth as possible to ensure that the operating element 811 can maintain engagement with the ratchet structure 211 after resetting. At the same time, it will not occupy too much internal space of the pen holder 61, thus preventing the pen holder 61 from becoming too long. As the piston rod 21 moves along the first direction a, the teeth located in the receiving groove 632 gradually leave the receiving groove 632.

[0113] Furthermore, when assembling the atomizing device 100, the following steps are included:

[0114] 1) After assembling the piston rod 21 and the first piston 22 (for example, the two are engaged with each other by the snap-fit ​​part 213 and the snap-fit ​​groove 221), it is pre-assembled with the pen cap 63 to form the first pre-assembled component;

[0115] 2) Remove the bottle cap 13 from container assembly 1, assemble pen holder 61 and pen cap 62 (for example, by fastening protrusion 613 and fastening groove 622), and pre-assemble them with container assembly 1 to form a second pre-assembled assembly.

[0116] 3) Assemble the first pre-assembled component and the second pre-assembled component. Insert the piston rod 21 and the first piston 22 into the container 11 and rotate the pen cap 63 so that the pen cap 63 is screwed into the pen barrel 61. It should be understood that in this step, in order to prevent the first material in the first chamber 31 from spilling out from the second end of the container 11, the second end of the container 11 needs to be placed upwards before assembly. When the piston rod 21 and the first piston 22 are inserted into the container 11, the insertion of the first piston 22 first causes the first material to move from the first chamber 31 to the second chamber 32. During this process, the ratchet structure 211 is located above the pawl 82. When the first pre-assembled component and the second pre-assembled component are assembled, the pawl 82 engages with the first tooth below the ratchet structure 211.

[0117] 4) Assemble the pen cap 63 into the pen holder 61 to complete the assembly of the atomizing device 100.

[0118] It should be noted that the various embodiments provided in this application belong to the same concept; the technical features in the technical solutions described in each embodiment can be arbitrarily combined without conflict. The above descriptions are merely embodiments of this application and are not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principle of this application should be included within the scope of the claims of this application.

Claims

1. An atomizing device, the atomizing device comprising: A container assembly comprising a container and a sealing plug, the container having an open first end and a second end, the sealing plug being used to seal the first end; A piston assembly includes a piston rod, a first piston, and a second piston, wherein the first piston and the second piston are sequentially disposed in the container along a first direction, and one end of the piston rod is located in the container and is linked to the first piston. In the container cavity, the side of the second piston facing away from the sealing plug forms a first chamber, and the second piston and the sealing plug form a second chamber; the first chamber is used to contain a first raw material, and the second chamber is used to contain a second raw material; When the piston rod pushes the first piston to move relative to the second piston in a first direction, the first raw material enters the second chamber and mixes with the second raw material to form a mixture, and in this process, the sealing plug is dislodged from the first end under the pressure of the mixture.

2. The atomizing device according to claim 1, wherein, During the assembly of the piston rod into the container, the piston rod pushes the first piston to move relative to the second piston in a first direction, so that the first raw material enters the second chamber.

3. The atomizing device according to claim 1, wherein, When the first piston moves in the first direction to abut against the second piston, the first raw material completely enters the second chamber.

4. The atomizing device according to claim 1, wherein, The first raw material is in liquid form, and the second raw material is in freeze-dried powder or liquid form.

5. The atomizing device according to claim 4, wherein, The second raw material is a lyophilized powder nanobody.

6. The atomizing device according to claim 1, wherein, The sealing plug is a rubber plug.

7. The atomizing device according to any one of claims 1-6, wherein, The inner wall of the container is provided with a groove, which forms a communicating flow channel with the outer wall of the second piston, and the first chamber and the second chamber are connected through the communicating flow channel; Under the compression of the first piston or the action of the air pressure in the first chamber, the first raw material enters the second chamber through the connecting channel.

8. The atomizing device according to any one of claims 1-6, wherein, The atomizing device also includes an atomizing chip, which is located outside the sealing plug; When the hydraulic pressure of the liquid flowing out from the first end reaches a preset value, the liquid is processed by the atomizing chip to form atomized fine particles and then escapes.

9. The atomizing device according to claim 8, wherein, The sealing plug is disposed in the port of the first end and the two are interference fit.

10. The atomizing device according to claim 9, wherein, When the sealing plug detaches from the first end, the sealing plug abuts against the atomizing chip under the compression of the mixture.

11. The atomizing device according to claim 10, wherein, The sealing plug includes a sealing plug body and a plurality of protruding structures, wherein the protruding structures are disposed on the side of the sealing plug body facing the atomizing chip; When the sealing plug detaches from the first end, the protruding structure forms a first gap between the sealing plug body and the atomizing chip, through which the mixture in the second chamber flows to the atomizing channel of the atomizing chip.

12. The atomizing device according to claim 11, wherein, The atomizing device further includes a pen holder, which has a first hollow column and a second hollow column connected sequentially along a first direction; the container assembly and the piston assembly are both disposed in the pen holder, and the atomizing chip is installed in the second hollow column; When the sealing plug detaches from the first end, the sealing plug body is located in the first hollow column, and a second gap is formed between the circumferential surface wall of the sealing plug body and the inner wall of the first hollow column. The second chamber, the second gap, the first gap and the atomizing channel are connected in sequence.

13. The atomizing device according to claim 12, wherein, The lateral space dimension of the first hollow column is larger than that of the second hollow column; when the sealing plug is detached from the first end, the protruding structure abuts against the end face of the second hollow column to reduce or completely avoid the protruding structure covering the atomizing channel.

14. The atomizing device according to claim 12, wherein, The sealing plug body includes a first column and a second column connected sequentially along a first direction; The first column is frustum-shaped and gradually expands along the first direction; The second column is cylindrical, and its outer diameter is greater than or equal to the maximum outer diameter of the first column; when the sealing plug is assembled in the port of the first end, the outer wall of the second column is interference-fitted with the inner wall of the first end.

15. The atomizing device according to claim 14, wherein, The protruding structure protrudes outward from the circumferential surface of the second column; When the sealing plug is fitted into the port of the first end, the protruding structure is squeezed and deformed by the inner wall of the first end.

16. The atomizing device according to claim 12, wherein, The atomizing device also includes a pen cap, which is connected to the first end of the pen holder; The pen cap is provided with a sealing post, which is inserted into the second hollow post and the two are interference-fitted to seal the first end of the pen barrel.

17. The atomizing device according to claim 16, wherein, The atomizing device also includes a pen cap, which is connected to the second end of the pen barrel to seal the second end of the pen barrel.

18. The atomizing device according to claim 12, wherein, The atomizing device also includes a retainer for holding the container, which is mounted in the pen holder.

19. The atomizing device according to any one of claims 1-6, wherein, The atomizing device further includes a pen holder and a trigger assembly, wherein both the container assembly and the piston assembly are disposed within the pen holder; the trigger assembly includes: An operating mechanism is movably mounted on the pen holder; A pawl, rotatably connected to the operating mechanism, is used to engage with a ratchet structure provided on the piston rod; When the operating mechanism moves along the first direction under external force, the pawl pushes the ratchet structure to make the piston rod move along the first direction, and the piston rod pushes the first piston and the second piston to move to trigger atomization; When the operating mechanism moves in the second direction, the piston rod does not move with it, and the first direction is opposite to the second direction.

20. The atomizing device according to claim 19, wherein, The operating mechanism is provided with a limiting structure to limit the rotation angle of the pawl, so that the pawl can maintain engagement with the ratchet structure during the movement of the operating mechanism in the first direction.

21. The atomizing device according to claim 19, wherein, The operating mechanism includes: An operating element, which is at least partially located outside the pen holder; An adapter element is located inside the pen holder and connected to the operating element, and the pawl is rotatably connected to the adapter element.

22. The atomizing device according to claim 19, wherein, The atomizing device also includes a pen cap, which is connected to the second end of the pen barrel to seal the second end of the pen barrel; The pen cap is provided with a limiting groove, and the piston rod is provided with a limiting protrusion; the limiting groove and the limiting protrusion are engaged to restrict the piston rod from rotating relative to the pen cap.

23. The atomizing device according to claim 22, wherein, The pen cap is also provided with a receiving groove; when the atomizing device is in the initial state, the ratchet structure is partially located in the receiving groove.

24. The atomizing device according to claim 23, wherein, The atomizing device also includes a pen cap, which is connected to the first end of the pen holder; When assembling the atomizing device, the piston rod is assembled with the first piston and then pre-assembled with the pen cap to form a first pre-assembled assembly; the pen barrel and the pen cap are assembled and then pre-assembled with the container assembly to form a second pre-assembled assembly; then, the first pre-assembled assembly and the second pre-assembled assembly are assembled, and when the two are assembled, the pawl engages with the ratchet structure.

Images