Flash filtration device and experimental platform
By designing an automated flash filtration device, the flash filtration process is realized using mechanized pressure filtration and clamping components, which solves the problems of low efficiency, large error and low safety of manual operation, and improves experimental efficiency and safety.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- SHENZHEN JINGTAI TECH CO LTD
- Filing Date
- 2025-06-25
- Publication Date
- 2026-07-30
AI Technical Summary
In existing chemical experiments, manual filtration is inefficient, prone to errors, and unsafe, and can easily cause pollution and health risks.
Design a flash filtration device, including a support assembly, a filter press assembly, and a clamping assembly, to automatically complete the flash filtration process through mechanization. The filter press plate and the clamping mechanism are used to press the inner tube of the flash filtration bottle and filter the material, reducing manual operation.
It improved experimental efficiency, reduced contamination and errors caused by manual operation, and enhanced experimental safety.
Smart Images

Figure CN2025103621_30072026_PF_FP_ABST
Abstract
Description
Flash filtration device and experimental platform
[0001] This application claims priority to Chinese Patent Application No. 202510126693.7, filed on January 27, 2025, entitled "Flash Filter Device and Experimental Platform", the entire contents of which are incorporated herein by reference. Technical Field
[0002] This application relates to the field of automated equipment technology, specifically to a flash filter device and experimental platform. Background Technology
[0003] In chemical experiments, the reacted samples often need to be filtered, and the resulting clear liquid is then analyzed and tested. In common techniques, researchers manually draw up the mother liquor using a plunger-type syringe, attach a filter head to the end of the syringe, and then press down the plunger to force the mother liquor through the filter head. This manual process is cumbersome and inefficient, requiring significant manpower for repetitive tasks. Furthermore, manual operation can easily contaminate the experimental samples, introduce experimental errors, and some hazardous samples can adversely affect the health of the researchers. Summary of the Invention
[0004] The purpose of this application is to provide a flash filter device and experimental platform to solve the problems of low efficiency, large experimental error, and low safety in manual experiments.
[0005] To achieve the objectives of this application, the following technical solution is provided:
[0006] In a first aspect, this application provides a flash filtration device, including a support assembly, a filter press assembly, and a first clamping assembly. The filter press assembly includes a filter press plate, which is slidably connected to the support assembly and is movable along a first direction. The first clamping assembly includes a first clamping tube mechanism, which is slidably connected to the support assembly and is movable along a second direction, which intersects with the first direction.
[0007] The first clamping mechanism is used to clamp and move the inner tube of the flash filter bottle and extend part of the inner tube of the flash filter bottle into the outer tube of the flash filter bottle. The filter press plate is used to press the inner tube of the flash filter bottle into the outer tube of the flash filter bottle.
[0008] In one embodiment, the support assembly includes a support column and a movable plate. The support column extends along a first direction, and the movable plate is slidably connected to the support column and is movable along the first direction. The filter press plate is slidably connected to the movable plate and is movable along a second direction. The first clamping mechanism is slidably connected to the movable plate and is movable along the second direction. The first clamping mechanism is also movable relative to the filter press plate along the first direction.
[0009] In one embodiment, the support assembly further includes a top plate and a first lifting mechanism. The top plate is fixedly connected to the support column, and the first lifting mechanism is disposed on the top plate and connected to the movable plate. The first lifting mechanism is used to drive the movable plate to move along the first direction.
[0010] In one embodiment, the filter press assembly further includes a first translation mechanism and a first slide table. The first translation mechanism is disposed on the movable plate, the first slide table is slidably connected to the movable plate along the second direction, and the filter press plate is connected to the first slide table. The first translation mechanism is connected to the first slide table and is used to drive the first slide table to move along the second direction.
[0011] In one embodiment, the first clamping assembly further includes a guide shaft, a second slide, and a second lifting mechanism. The guide shaft extends along the first direction, and one end of the guide shaft is connected to the first slide and the other end is connected to the filter plate. The second slide is slidably connected to the guide shaft. The first tube clamping mechanism is connected to the second slide. The second lifting mechanism is disposed on the first slide and connected to the second slide. The second lifting mechanism is used to drive the second slide to move along the first direction.
[0012] In one embodiment, the support assembly includes a support frame and a first lifting mechanism disposed on the support frame. The first lifting mechanism is connected to the filter press plate and is used to drive the filter press plate to move along the first direction.
[0013] In one embodiment, the first clamping mechanism is slidably connected to the filter press plate and is movable along the second direction; the filter press assembly further includes a first translation mechanism, which is disposed on the filter press plate, connected to the first clamping mechanism, and used to drive the first clamping mechanism to move along the second direction.
[0014] In one embodiment, the filter press assembly further includes a pressure sensor disposed on the movable plate, the pressure sensor being used to abut against the first lifting mechanism to obtain pressure data; or, the pressure sensor is disposed on the first lifting mechanism, the pressure sensor being used to abut against the movable plate to obtain pressure data; wherein, the pressure data is used to characterize the moving distance of the filter press plate along the first direction.
[0015] In one embodiment, the first lifting mechanism includes a first lifting drive component and a first transmission rod. The first lifting drive component is disposed on the top plate, and the first transmission rod is connected to the movable plate. The first lifting drive component and the first transmission rod are in a transmission cooperation to drive the movable plate to move along the first direction. The first lifting mechanism also includes a first floating joint and a second floating joint. The first floating joint is connected to the first transmission rod, and the second floating joint is fixedly connected to the movable plate and movably connected to the first transmission rod. The pressure sensor is disposed on the first floating joint or the second floating joint and is located between the first floating joint and the second floating joint.
[0016] In one embodiment, the first clamping mechanism includes a first clamping drive, a first clamping part, and a second clamping part. The first clamping drive is disposed on the second slide. At least one of the first clamping part and the second clamping part is connected to the first clamping drive, and the first clamping drive is used to cause the first clamping part and the second clamping part to move relative to each other to clamp the inner tube of the flash filter bottle.
[0017] In one embodiment, the first clamping part includes a first mounting plate and multiple sets of first fingers, the multiple sets of first fingers being spaced apart on the first mounting plate, and each set of first fingers including at least one first finger; the second clamping part includes a second mounting plate and multiple sets of second fingers, the multiple sets of second fingers being spaced apart on the second mounting plate, and each set of second fingers including at least one second finger; the multiple sets of first fingers and the multiple sets of second fingers correspond one-to-one, and the first fingers and second fingers are used to move relative to each other to clamp the inner tube of the flash filter bottle.
[0018] In one embodiment, the first clamping mechanism further includes a first transmission member and a second transmission member, the first clamping drive member being connected to the first transmission member and the second transmission member respectively, the first transmission member being fixedly connected to the first clamping part, the second transmission member being fixedly connected to the second clamping part, and the first clamping drive member being used to drive the first transmission member and the second transmission member to move in opposite directions; at least one of the first transmission member and the second transmission member includes a rack.
[0019] In one embodiment, the flash filtration device further includes a liquid addition assembly, which is connected to the pressure filtration assembly and is used to add sample solution or diluent to the outer tube of the flash filtration bottle;
[0020] The liquid addition assembly includes a liquid addition needle and a liquid addition pump. The liquid addition needle is connected to the filter plate, and the liquid addition pump is connected to the liquid addition needle and is used to output sample liquid or diluent to the liquid addition needle.
[0021] In one embodiment, the liquid dosing assembly further includes a cleaning mechanism, which includes a cleaning tank and a cleaning pump. The cleaning pump is connected to the cleaning tank. The cleaning tank is used to contain at least a portion of the liquid dosing needle and to hold cleaning waste liquid. The cleaning pump is used to discharge the cleaning waste liquid from the cleaning tank.
[0022] In one embodiment, the flash filtration device further includes a flash filtration bottle transfer assembly, which includes a flash filtration bottle tray placement seat for holding the inner tube of the flash filtration bottle and / or the outer tube of the flash filtration bottle.
[0023] In one embodiment, the flash filter bottle tray holder includes a first tray holder and a second tray holder, the first tray holder and the second tray holder being arranged along the second direction, one of the first tray holder and the second tray holder being used to hold the inner tube of the flash filter bottle, and the other being used to hold the outer tube of the flash filter bottle; the first tray holder and the second tray holder are spaced apart in the first direction, and the first tray holder is closer to the filter press plate in the first direction than the second tray holder.
[0024] In one embodiment, the filter press plate and the first clamping mechanism are spaced apart along a third direction. The flash filter bottle tray placement seat includes a first tray placement seat and a second tray placement seat. The first tray placement seat and the second tray placement seat are arranged along the third direction. One of the first tray placement seat and the second tray placement seat is used to hold the inner tube of the flash filter bottle, and the other is used to hold the outer tube of the flash filter bottle. The third direction intersects with both the first direction and the second direction.
[0025] In one embodiment, the flash filter bottle transfer assembly further includes a first moving mechanism, which is connected to the flash filter bottle tray placement seat and is used to drive the flash filter bottle tray placement seat to move along the second direction and / or a third direction, wherein the third direction intersects both the first direction and the second direction.
[0026] In one embodiment, the flash filtration device further includes a baffle plate disposed on the support assembly and spaced apart from the flash filtration bottle tray placement seat in the first direction. The baffle plate has a through hole along the first direction, the diameter of which is smaller than the outer diameter of the inner tube of the flash filtration bottle. The flash filtration bottle tray placement seat can be moved to the baffle plate under the drive of the first moving mechanism.
[0027] Secondly, this application also provides an experimental platform, including a base and a flash filter device as described in any one of the various embodiments of the first aspect, wherein a support component of the flash filter device is mounted on the base.
[0028] In one embodiment, the experimental platform further includes a sampling device, which includes a pipetting assembly for transferring sample liquid or diluent into the outer tube of the flash filtration bottle, or for extracting filtrate from the inner tube of the filtered flash filtration bottle.
[0029] In one embodiment, the support assembly includes a support column, a top plate, and a side plate. The support column extends along the first direction. The top plate is fixedly connected to the support column, and the side plate is fixedly connected to the top plate and / or the support column. The pipetting assembly includes a pipette tip mounting base and a pipetting pump. The pipette tip mounting base is used to mount a pipette tip. The pipetting pump communicates with the pipette tip and transfers the sample solution or diluent to the outer tube of the flash filtration bottle through the pipette tip. The sampling device further includes a second translation mechanism and a third slide. The second translation mechanism is disposed on the side plate, and the third slide is slidably connected to the side plate along the second direction or the third direction. The second translation mechanism is connected to the third slide and is used to drive the third slide to move relative to the side plate. The pipetting assembly is slidably connected to the third slide and is capable of moving relative to the third slide along the first direction.
[0030] In one embodiment, the pipetting assembly further includes a fourth slide and a third lifting mechanism. The third lifting mechanism is disposed on the third slide, the fourth slide is slidably connected to the third slide along the first direction, and the pipetting head mounting base is connected to the fourth slide. The third lifting mechanism is connected to the fourth slide and is used to drive the fourth slide to move along the first direction.
[0031] In one embodiment, the third slide is slidably connected to the side plate along the second direction; the pipetting assembly further includes a first mounting platform and a pitch-changing mechanism, and there are multiple pipetting head mounting seats. The first mounting platform is fixedly connected to the fourth slide, and the multiple pipetting head mounting seats are slidably connected to the first mounting platform and can move along the third direction. The pitch-changing mechanism is disposed on the first mounting platform and connected to the multiple pipetting head mounting seats. The pitch-changing mechanism is used to drive the pipetting head mounting seats to move along the third direction to adjust the distance between any two adjacent pipetting head mounting seats.
[0032] In one embodiment, the pitch-changing mechanism includes a pitch-changing drive and an adjusting plate. The pitch-changing drive is disposed on the first mounting platform, the adjusting plate is convexly connected to the pitch-changing drive, and a plurality of pipette head mounting seats are movably connected to the adjusting plate. The pitch-changing drive is used to drive the adjusting plate to move in the first direction, so as to drive the plurality of pipette head mounting seats to move along the third direction.
[0033] In one embodiment, the pipetting assembly further includes a lower pressure plate, a lower pressure mechanism, and a plurality of separating members. The separating members are disposed on the lower pressure plate and slidably connected to the lower pressure plate. Each of the plurality of separating members corresponds to a plurality of pipetting head mounting seats and can move synchronously with the pipetting head mounting seats along the third direction. The separating members can also move relative to the pipetting head mounting seats along the first direction. The lower pressure mechanism is disposed on the first mounting platform and connected to the lower pressure plate. The lower pressure mechanism is used to drive the separating members to move along the first direction to separate the pipetting head and the pipetting head mounting seat.
[0034] In one embodiment, the sampling device further includes a second clamping assembly connected to the fourth slide table for clamping and moving a test tube, the test tube being used to hold a sample solution or diluent; the second clamping assembly includes a second mounting platform, a fourth lifting mechanism, and a second tube clamping mechanism, the second mounting platform being fixedly connected to the fourth slide table, the fourth lifting mechanism being disposed on the second mounting platform and connected to the second tube clamping mechanism, the fourth lifting mechanism being used to drive the second tube clamping mechanism to move relative to the second mounting platform along the first direction, the second tube clamping mechanism being used to clamp the test tube.
[0035] In one embodiment, the second clamping mechanism includes a second clamping drive, a third clamping part, and a fourth clamping part. The second clamping drive is connected to the fourth lifting mechanism. At least one of the third clamping part and the fourth clamping part is connected to the second clamping drive. The second clamping drive is used to cause the third clamping part and the fourth clamping part to move relative to each other to clamp the test tube.
[0036] In one embodiment, the third clamping part includes a third mounting plate and multiple sets of third fingers, the multiple sets of third fingers being spaced apart on the third mounting plate, and each set of third fingers including at least one third finger; the fourth clamping part includes a fourth mounting plate and multiple sets of fourth fingers, the multiple sets of fourth fingers being spaced apart on the fourth mounting plate, and each set of fourth fingers including at least one fourth finger; the multiple sets of third fingers and the multiple sets of fourth fingers correspond one-to-one, and the third fingers and the fourth fingers are used to move relative to each other to clamp the test tube.
[0037] In one embodiment, the third clamping part further includes a mounting shaft, a limiting ring, and a preload spring. The mounting shaft is connected to the third mounting plate and extends along the moving direction of the third clamping part. Each group of third fingers is slidably connected to the mounting shaft. A limiting ring is provided on the side of each group of third fingers away from the corresponding fourth finger. The limiting ring is sleeved on the mounting shaft and fixedly connected to the mounting shaft. A preload spring is provided between each group of third fingers and the corresponding limiting ring. One end of the preload spring elastically abuts against the limiting ring, and the other end elastically abuts against the third finger.
[0038] In one embodiment, the second clamping mechanism further includes a third transmission member and a fourth transmission member. The second clamping drive member is connected to the third transmission member and the fourth transmission member respectively. The third transmission member is fixedly connected to the third clamping part, and the fourth transmission member is fixedly connected to the fourth clamping part. The second clamping drive member is used to drive the third transmission member and the fourth transmission member to move in opposite directions.
[0039] In one embodiment, the second clamping assembly further includes a buffer mechanism and a third mounting platform. The third mounting platform is connected to the fourth lifting mechanism. The buffer mechanism is disposed between the third mounting platform and the second clamping mechanism and is used to move the second clamping mechanism relative to the third mounting platform in the first direction.
[0040] In one embodiment, the sampling device further includes a pipette tray assembly, which includes a pipette tray placement seat and a second moving mechanism. The pipette tray placement seat is slidably connected to the base and is movable along the second direction and / or the third direction. The second moving mechanism is disposed on the base and connected to the pipette tray placement seat. The second moving mechanism is used to drive the pipette tray placement seat to move relative to the base. The pipette tray placement seat is used to hold the pipette.
[0041] In one embodiment, the pipette tray assembly further includes a pipette mounting bracket connected to the second moving mechanism, a pipette tray placement seat disposed on the pipette mounting bracket, and a clearance space between the pipette mounting bracket and the base, the clearance space being capable of accommodating at least a portion of the flash filtration bottle tray placement seat.
[0042] In one embodiment, the sampling device further includes a test tube holder assembly, which includes a test tube holder base and a test tube mounting rack. The test tube mounting rack is mounted on the base and is spaced apart from the flash filtration device in the third direction and from the pipette tray assembly in the second direction. The test tube holder base is disposed on the test tube mounting rack and is used to hold the test tubes.
[0043] In one embodiment, the test tube holder assembly further includes a third moving mechanism, which is disposed on the test tube mounting frame and connected to the test tube holder placement seat. The third moving mechanism is used to drive the test tube holder placement seat to move along the second direction and / or the third direction.
[0044] In one embodiment, the sampling device further includes a third clamping assembly disposed near the test tube holder assembly, the third clamping assembly being used to open and close the cap of the test tube;
[0045] The third clamping assembly includes a third tube clamping mechanism, which is used to clamp the tube body of the test tube and rotate it about a first axis. The third tube clamping mechanism can cooperate with the second tube clamping mechanism to open or close the test tube.
[0046] In one embodiment, the third clamping mechanism includes a third clamping drive, a finger mounting base, and a plurality of fifth fingers. The third clamping drive is disposed on the finger mounting base, and the plurality of fifth fingers are spaced apart circumferentially along the finger mounting base and slidably connected to the finger mounting base. The third clamping drive is connected to the fifth fingers and is used to drive the fifth fingers to move radially along the finger mounting base to clamp the tube body of the test tube.
[0047] In one embodiment, there are multiple third clamping mechanisms. The third clamping assembly further includes a rotary drive, a first gear, and a second gear. The rotary drive is connected to the first gear. Each third clamping mechanism is connected to the second gear, and the second gear is coaxially arranged with the third clamping mechanism. The first gear meshes with one of the second gears, and two adjacent second gears mesh. The rotary drive is used to drive the first gear to rotate, thereby driving multiple third clamping mechanisms to rotate synchronously around the first axis through the second gear.
[0048] In one embodiment, a magnet mounting plate is provided on the side of the test tube mounting rack near the third clamping assembly. The magnet mounting plate extends toward the arrangement direction of the plurality of third tube clamping mechanisms. A plurality of magnets are spaced apart on the magnet mounting plate, and the plurality of magnets correspond one-to-one with the plurality of third tube clamping mechanisms.
[0049] By setting the movable plate to move relative to the support column in the first direction, the first clamping tube mechanism is slidably connected to the movable plate. The first clamping tube mechanism is used to clamp the inner tube of the flash filtration bottle and can move the inner tube of the flash filtration bottle above the outer tube of the flash filtration bottle in the second direction. The filter pressing plate is slidably connected to the movable plate and can move in the second direction. It can also move in the first direction under the drive of the movable plate, which can accurately press the inner tube of the flash filtration bottle into the outer tube of the flash filtration bottle. The flash filtration device can complete the flash filtration work without manual operation, which can improve experimental efficiency, reduce the pollution that may be caused by manual operation, reduce experimental errors, and improve experimental safety. Attached Figure Description
[0050] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.
[0051] Figure 1 is a perspective view of a flash filter device according to an embodiment;
[0052] Figure 2 is a perspective view of the flash filter device of one embodiment from another angle;
[0053] Figure 3 is a front view of a flash filter device according to an embodiment;
[0054] Figure 4 is a perspective view of the first clamping tube mechanism according to an embodiment;
[0055] Figure 5 is a perspective view of a flash filter bottle transfer assembly according to one embodiment;
[0056] Figure 6 is a perspective view of the experimental platform of one embodiment;
[0057] Figure 7 is a perspective view of the experimental platform of one embodiment from another angle;
[0058] Figure 8 is a perspective view of a sampling device according to an embodiment;
[0059] Figure 9 is a perspective view of a pipetting assembly according to an embodiment;
[0060] Figure 10 is a front view of a pipetting assembly according to an embodiment;
[0061] Figure 11 is a perspective view of a second clamping mechanism according to an embodiment;
[0062] Figure 12 is a front view of the second clamping mechanism according to an embodiment;
[0063] Figure 13 is a perspective view of a pipette tip tray assembly according to one embodiment;
[0064] Figure 14 is a perspective view of a test tube holder assembly according to one embodiment;
[0065] Figure 15 is a front view of a third clamping assembly according to an embodiment;
[0066] Figure 16 is a cross-sectional view of a third clamping assembly according to an embodiment;
[0067] Figure 17 is a perspective view of a flash filter device according to another embodiment;
[0068] Figure 18 is a perspective view of a flash filter device according to another embodiment.
[0069] Explanation of reference numerals in the attached drawings: 1000-Experimental platform, 100-Flash filter device, 10-Support assembly, 11-Support column, 12-Modible plate, 212-First slide rail, 13-Top plate. 14-First lifting mechanism, 141-First lifting drive component, 142-First transmission rod, 143-First floating joint, 144-Second floating joint, 145-Pressure sensor, 15-Side plate, 151-Second slide rail, 16-Support frame, 161-First plate, 162-Second plate, 163-First guide slide rail, 20-Filter press assembly, 21-Filter press plate, 22-First translation mechanism, 221-First translation drive component, 222-First transmission part, 23-First slide table, 24-Second guide slide rail, 30-First clamping assembly, 31-First pipe clamping mechanism, 311-First clamping drive component, 312-First clamping part, 3121-First mounting plate, 312 2-First finger, 313-Second clamping part, 3131-Second mounting plate, 3132-Second finger, 314-First transmission component, 32-Guide shaft, 33-Second slide, 34-Second lifting mechanism, 341-Second lifting drive component, 342-Second transmission rod, 40-Liquid filling assembly, 41-Liquid filling needle, 42-Liquid filling pump, 43-Liquid filling needle mounting seat, 44-Cleaning mechanism, 441-Cleaning tank, 442-Cleaning pump, 443-Cleaning tank mounting bracket, 50-Flash filtration bottle transfer assembly, 51-Flash filtration bottle tray placement seat, 511-First tray placement seat, 512-Second tray placement seat, 513-Connecting plate, 52-First moving mechanism, 521-First moving... 522-Second transmission unit, 53-Mounting base, 531-Sliding guide rail, 54-Baffle, 541-Through hole, 200-Base, 300-Sampling device, 301-Second translation mechanism, 302-Third slide, 303-Second translation drive, 304-Third transmission unit, 60-Pipe assembly, 61-Pipe head mounting base, 62-Pipe pump, 63-Fourth slide, 64-Third lifting mechanism, 641-Third lifting drive, 65-First mounting platform, 651-Mounting back plate, 652-First horizontal rail, 653-Vertical rail, 66-Pitch mechanism, 661-Pitch drive, 662-Adjusting plate, 663-Pitch transmission component, 6 7-Pressing plate, 68-Pressing mechanism, 681-Pressing drive component, 682-Pressing transmission component, 683-Sensing component, 684-Second horizontal track, 69-Separation component, 691-Spring buffer structure, 70-Second clamping assembly, 71-Second mounting platform, 72-Fourth lifting mechanism, 721-Fourth lifting drive component, 73-Second clamping tube mechanism, 731-Second clamping drive component, 732-Third clamping part, 7321-Third mounting plate, 7322-Third finger, 7323-Mounting shaft, 7324-Limiting ring, 7325-Preload spring, 733-Fourth clamping part, 7331-Fourth mounting plate, 7332-Fourth finger, 734-First fixing plate.735-Second fixing plate, 736-Slider, 737-Finger mounting component, 738-Third transmission component, 739-Fourth transmission component, 74-Buffer mechanism, 75-Third mounting platform, 80-Pipette tray assembly, 81-Pipette tray holder, 821-Second moving drive component, 822-Fourth transmission component, 83-Fixed seat, 84-Pipette mounting bracket, 841-Clearing space, 90-Test tube holder assembly, 91-Test tube holder holder, 92-Test tube mounting bracket, 921-Magnet mounting plate, 922- Magnet, 93-Third clamping assembly, 931-Third clamping mechanism, 9311-Third clamping drive, 9312-Finger mounting base, 9313-Fifth finger, 9314-Electrical slip ring, 932-Rotation drive, 933-First gear, 934-Second gear, 935-Third gear, 94-Gripper bracket, 2001-Inner tube of flash filtration bottle, 2002-Outer tube of flash filtration bottle, 2003-Pipette, 2004-Test tube, Z-First direction, X-Second direction, Y-Third direction, L1-First axis. Detailed Implementation
[0070] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0071] It should be noted that when a component is said to be "fixed" to another component, it can be directly on the other component or it can be in a middle component. When a component is said to be "connected" to another component, it can be directly connected to the other component or it may be in a middle component.
[0072] Unless otherwise defined, all technical and scientific terms used in this application have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains. The terminology used in the specification of this application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. The term "and / or" as used in this application includes any and all combinations of one or more of the associated listed items.
[0073] The following detailed description of some embodiments of this application is provided in conjunction with the accompanying drawings. Unless otherwise specified, the following embodiments and features can be combined with each other.
[0074] Please refer to Figures 1 to 7, 17 and 18. This application provides a flash filtration device 100, including a support assembly 10, a filter press assembly 20 and a first clamping assembly 30.
[0075] First, define the directions. Please refer to Figure 1. Z is the first direction, X is the second direction, and Y is the third direction. The first direction Z, the second direction X, and the third direction Y intersect each other. Optionally, the first direction Z, the second direction X, and the third direction Y are perpendicular to each other.
[0076] The filter press assembly 20 includes a filter press plate 21, which is slidably connected to the support assembly 10 and is movable along a first direction Z. The first clamping assembly 30 includes a first clamping mechanism 31, which is slidably connected to the support assembly 10 and is movable along a second direction X.
[0077] The support component 10 can be made of a material with high structural strength, specifically metal materials, high-strength plastics, ceramics, etc. Metal materials include aluminum, aluminum alloys, magnesium alloys, iron and iron alloys, etc.
[0078] In one embodiment, as shown in Figures 1 to 7, the support assembly 10 includes a support column 11 and a movable plate 12. The support column 11 extends along a first direction Z, and the movable plate 12 is slidably connected to the support column 11 and is movable along the first direction Z. The filter press plate 21 is slidably connected to the movable plate 12 and is movable along a second direction X. The first clamping mechanism 31 is slidably connected to the movable plate 12 and is movable along the second direction X. The first clamping mechanism 31 is also movable relative to the filter press plate 21 along the first direction Z.
[0079] Optionally, the filter press plate 21 and / or the first clamping mechanism 31 can also move along a third direction Y, which can expand the range of motion and improve flexibility. For example, in addition to moving together with the filter press plate 21 along the second direction X, the first clamping mechanism 31 can also move relative to the filter press plate 21 along the third direction Y; or, in addition to moving together with the first clamping mechanism 31 along the second direction X, the filter press plate 21 can also move relative to the first clamping mechanism 31 along the third direction Y.
[0080] There can be one or more support columns 11, without limitation. Optionally, there can be multiple support columns 11, spaced apart, with the movable plate 12 slidably connected to all support columns 11. As shown in Figure 1, the movable plate 12 is a square plate, and there are four support columns 11 located at the four corners of the movable plate 12. These support columns not only provide stable support for the movable plate 12 but also avoid interference with other components above and below the movable plate 12. The support columns 11 can be columnar, plate-shaped, rod-shaped, etc., without limitation. The movable plate 12 and the support columns 11 can be slidably connected by at least one method, such as linear bearings or slide rails.
[0081] The filter press plate 21 and the movable plate 12 can be directly connected or indirectly connected, without any specific limitation. Optionally, the filter press plate 21 can also move relative to the movable plate 12 in the first direction Z; or, the filter press plate 21 can move synchronously with the movable plate 12 in the first direction Z.
[0082] Optionally, the first clamping mechanism 31 and the filter press plate 21 can move synchronously along the second direction X; or, the first clamping mechanism 31 and the filter press plate 21 can move independently of each other along the second direction X, without limitation. Optionally, the first direction Z is the height direction of the flash filter device 100, and the second direction X is the horizontal direction of the flash filter device 100, such as the length direction of the movable plate 12, or the arrangement direction of the filter press assembly 20 and the first clamping assembly 30 (such as the front-back direction or the left-right direction). In this case, the filter press plate 21 and the first clamping mechanism 31 can be spaced apart in the second direction X, or spaced apart in the third direction Y. Optionally, the first direction Z is the horizontal direction of the flash filter device 100, and the second direction X is the height direction of the flash filter device 100, without limitation. In this case, the filter press plate 21 and the first clamping mechanism 31 can be spaced apart in the first direction Z, or spaced apart in the third direction Y.
[0083] The flash filtration device 100 is used to filter the sample solution in the flash filtration bottle. The flash filtration bottle can be used for rapid filtration of chromatographic injection solvents. The flash filtration bottle includes an inner tube and an outer tube, and the inner tube can be nested inside the outer tube.
[0084] Specifically, a filter membrane is installed at the bottom of the inner tube of the flash filter flask. The bottom of the outer tube of the flash filter flask is sealed and used to hold the liquid to be filtered. When the inner tube of the flash filter flask is pressed into the outer tube, the liquid to be filtered passes through the filter membrane and enters the inner tube. The flash filter flask can adopt a common structure available on the market, and there are no restrictions here.
[0085] Optionally, the filtrate may include the sample solution, or the filtrate may include both the sample solution and a diluent. The sample solution is typically a raw liquid sample obtained from a organism or the environment, containing the substance or information to be detected. The diluent is typically water or another inert solvent used to dilute the viscous sample solution to an appropriate concentration range for more accurate analysis.
[0086] The first clamping mechanism 31 is used to clamp and move the inner tube 2001 of the flash filter bottle and extend part of the inner tube 2001 of the flash filter bottle into the outer tube 2002 of the flash filter bottle. The filter press plate 21 is used to press the inner tube 2001 of the flash filter bottle into the outer tube 2002 of the flash filter bottle.
[0087] Optionally, the first clamping mechanism 31 can operate on only a single flash filter bottle inner tube 2001, or it can clamp and move multiple flash filter bottle inner tubes 2001 simultaneously; there is no specific limitation. Similarly, during the movement of the filter press plate 21 along the first direction Z, it can press only one flash filter bottle inner tube 2001 into the flash filter bottle outer tube 2002, or it can press multiple flash filter bottle inner tubes 2001 into the flash filter bottle outer tube 2002 simultaneously; there is no limitation.
[0088] Specifically, the inner tube 2001 and outer tube 2002 of the flash filtration flask are placed alternately, with the outer tube 2002 containing the liquid to be filtered. A first clamping mechanism 31 is used to clamp the inner tube 2001 and move it along the second direction X above the outer tube 2002. Then, the filter press plate 21 moves relative to the movable plate 12 along the second direction X above the inner tube 2001 and outer tube 2002, and is approximately aligned with the end of the inner tube 2001 away from the bottom wall of the outer tube 2002. Then, the movable plate 12 slides relative to the support column 11 along the first direction Z, and drives the filter press plate 21 to move along the first direction Z toward the inner tube 2001 of the flash filtration bottle until the filter press plate 21 abuts against the inner tube 2001 of the flash filtration bottle and presses the inner tube 2001 of the flash filtration bottle into the outer tube 2002 of the flash filtration bottle. At this time, the inner tube 2001 of the flash filtration bottle applies pressure to the outer tube 2002 of the flash filtration bottle so that the liquid to be filtered in the outer tube 2002 of the flash filtration bottle is filtered through the filter membrane at the bottom of the inner tube 2001 of the flash filtration bottle and enters the inner tube 2001 of the flash filtration bottle to filter the liquid to be filtered.
[0089] The flash filtration device 100 in this embodiment of the application is configured to move a movable plate 12 relative to the support column 11 along the first direction Z. The first clamping mechanism 31 is slidably connected to the movable plate 12. The first clamping mechanism 31 is used to clamp the inner tube 2001 of the flash filtration bottle and can move the inner tube 2001 of the flash filtration bottle above the outer tube 2002 of the flash filtration bottle along the second direction X. The filter pressing plate 21 is slidably connected to the movable plate 12 and can move along the second direction X. It can also move along the first direction Z under the drive of the movable plate 12, which can accurately press the inner tube 2001 of the flash filtration bottle into the outer tube 2002 of the flash filtration bottle. The flash filtration device 100 can complete the workflow without manual operation, which can improve experimental efficiency, reduce the pollution that may be caused by manual operation, reduce experimental errors, and improve experimental safety.
[0090] In one embodiment, as shown in Figures 1 and 2, the support assembly 10 further includes a top plate 13 and a first lifting mechanism 14. The top plate 13 is connected and fixed to the support column 11. The first lifting mechanism 14 is disposed on the top plate 13 and connected to the movable plate 12. The first lifting mechanism 14 is used to drive the movable plate 12 to move along the first direction Z.
[0091] The top plate 13 can improve the structural stability of the support assembly 10 and can also be used to install other components of the flash filter device 100. Optionally, the top plate 13 is generally rectangular and roughly parallel to the horizontal plane. The top plate 13 and the support column 11 can be an integral structure or a separate structure. The top plate 13 and the support column 11 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation. Optionally, the movable plate 12 is located between the top plate 13 and the end of the support column 11 away from the top plate 13.
[0092] Optionally, the first lifting mechanism 14 includes a first lifting drive component 141 and a first transmission rod 142. The first lifting drive component 141 is disposed on the top plate 13, and the first transmission rod 142 is connected to the movable plate 12 and extends along the first direction Z. The first lifting drive component 141 and the first transmission rod 142 are in a transmission engagement, and the first transmission rod 142 is driven to move along the first direction Z or rotate around its own axis.
[0093] Optionally, the first lifting drive component 141 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation. The first lifting drive component 141 can be used to drive the first transmission rod 142 to move along its own axial direction. The first lifting drive component 141 has a drive shaft, which can move linearly when the first lifting drive component 141 is running. For example, when the first lifting drive component 141 is a motor, the motor can be a linear motor or a lead screw motor, which enables its drive shaft to move linearly; or, for example, when the first lifting drive component 141 is a hydraulic cylinder or a pneumatic cylinder, the drive shaft is a piston rod, which can perform linear extension and retraction. Alternatively, the first lifting drive component 141 can also be used to drive the first transmission rod 142 to rotate around its own axis, without limitation.
[0094] The connection method between the first lifting drive component 141 and the top plate 13 can be welding, bonding, snap-fitting, screwing, riveting, etc., without restriction.
[0095] In one embodiment, the first lifting drive component 141 is a motor, and the first transmission rod 142 is a lead screw. The first lifting drive component 141 and the first transmission rod 142 are connected by a transmission connection (e.g., the drive shaft of the motor is connected to the first transmission rod 142 via a coupling). Optionally, the first transmission rod 142 rotates around its own axis under the drive of the first lifting drive component 141 and is connected to the movable plate 12 via a nut. The first transmission rod 142 and the nut form a lead screw and nut pair, which can convert the rotational motion of the first transmission rod 142 into the linear motion of the movable plate 12. The movable plate 12 can move relative to the support column 11 along the axial direction (i.e., the first direction Z) of the first transmission rod 142 under the transmission connection of the first transmission rod 142. Alternatively, the first lifting drive component 141 and the first transmission rod 142 are connected by a gear and rack pair, which can realize that the first transmission rod 142 moves relative to the support column 11 along its own axis, thereby driving the movable plate 12 to move relative to the support column 11 along the first direction Z. Both of the above transmission connection methods are acceptable and are not specifically limited.
[0096] By setting the first lifting mechanism 14, the first lifting mechanism 14 drives the movable plate 12 to move along the first direction Z, which has high transmission efficiency and the transmission method can be selected according to the actual product needs.
[0097] In one embodiment, as shown in FIG2, the filter press assembly 20 further includes a first translation mechanism 22 and a first slide 23. The first translation mechanism 22 is disposed on the movable plate 12, the first slide 23 is slidably connected to the movable plate 12 along the second direction X, and the filter press plate 21 is connected to the first slide 23. The first translation mechanism 22 is connected to the first slide 23 and is used to drive the first slide 23 to move along the second direction X.
[0098] The shape of the first slide 23 can be block-shaped, plate-shaped, column-shaped, or other irregular shapes, without limitation. The first slide 23 and the filter press plate 21 can be connected and fixed, or the filter press plate 21 can also move relative to the first slide 23 in the first direction Z.
[0099] Optionally, the surface of the movable plate 12 facing away from the top plate 13 is provided with a first slide rail 212, the first slide rail 212 extends along the second direction X, the first slide table 23 is slidably connected to the first slide rail 212, and is used to move relative to the first slide rail 212 along the second direction X under the drive of the first translation mechanism 22.
[0100] The first translation mechanism 22 can be any feasible drive transmission structure in the art. Optionally, the first translation mechanism 22 includes a first translation drive 221, which is disposed on the movable plate 12. Similar to the first lifting drive 141, the first translation drive 221 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation.
[0101] Optionally, the first translation drive 221 can be a linear motor, and the first translation mechanism 22 further includes a first transmission part 222. The first transmission part 222 includes a lead screw and nut pair (i.e., a lead screw and a nut disposed on the lead screw, the lead screw extending along the second direction X). The lead screw is connected to the drive shaft of the linear motor through a coupling, and the nut is connected to the first slide table 23. The linear motor drives the lead screw to rotate, so that the nut makes linear motion on the lead screw, thereby driving the first slide table 23 to move along the first slide rail 212 on the movable plate 12.
[0102] The filter press assembly 20 also includes a first translation mechanism 22 and a first slide 23. The filter press plate 21 is connected to the first slide 23. The first translation mechanism 22 is used to drive the first slide 23 to move along the second direction X, which can realize the movement of the filter press plate 21 in the second direction X. The filter press plate 21 can be accurately moved to the designated position and press the inner tube 2001 of the flash filter bottle into the outer tube 2002 of the flash filter bottle, which facilitates flexible operation of flash filter bottles in different positions and has high experimental accuracy.
[0103] In one embodiment, as shown in Figures 1 and 2, the first clamping assembly 30 further includes a guide shaft 32, a second slide 33, and a second lifting mechanism 34. The guide shaft 32 extends along a first direction Z, and one end of the guide shaft 32 is connected to the first slide 23, and the other end is connected to the filter press plate 21. The second slide 33 is slidably connected to the guide shaft 32. The first tube clamping mechanism 31 is connected to the second slide 33. The second lifting mechanism 34 is disposed on the first slide 23 and connected to the second slide 33. The second lifting mechanism 34 is used to drive the second slide 33 to move along the first direction Z.
[0104] There can be one or more guide shafts 32, without limitation. In one specific embodiment, as shown in Figure 2, there are two guide shafts 32 spaced apart, located at opposite ends of the filter press plate 21, capable of stably supporting the second slide table 33. Optionally, the guide shaft 32, the first slide table 23, and the filter press plate 21 can be an integral structure, or the guide shaft 32 and the first slide table 23, and the guide shaft 32 and the filter press plate 21 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation. The guide shaft 32 serves both as the connection structure between the filter press plate 21 and the first slide table 23, and as the guiding structure when the second slide table 33 moves relative to the filter press plate 21. This structural reuse simplifies the structural design and achieves lightweighting. It is understood that the guide shaft 32 can be replaced by a similar structure with equivalent function, such as a connecting plate and a slide rail on the connecting plate. The connecting plate connects the first slide table 23 and the filter press plate 21 respectively, and the second slide table 33 is connected to the slide rail via a slider.
[0105] The shape of the second slide 33 can be block-shaped, plate-shaped, column-shaped, or other irregular shapes, without limitation. Optionally, the second slide 33 is sleeved on the guide shaft 32 and can be slidably connected by a linear bearing. The first clamping mechanism 31 and the second slide 33 can be connected by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0106] The second lifting mechanism 34 can be any feasible drive transmission structure in the art. Optionally, the second lifting mechanism 34 includes a second lifting drive member 341 and a second transmission rod 342. The second lifting drive member 341 is disposed on the first slide table 23, and the second transmission rod 342 extends along the first direction Z and is drively connected to the second lifting drive member 341. Similarly, the second lifting drive member 341 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation. The second lifting drive member 341 can be used to drive the second transmission rod 342 to move along its own axial direction. The second lifting drive member 341 has a drive shaft, and the drive shaft can move linearly when the second lifting drive member 341 is running.
[0107] The connection method between the second lifting drive component 341 and the first slide 23 can be welding, bonding, snap-fitting, screwing, riveting, etc., without restriction.
[0108] Optionally, the second transmission rod 342 rotates around its own axis under the drive of the second lifting drive 341 and is connected to the second slide 33 through a nut. The second transmission rod 342 and the nut form a screw-nut pair, which can convert the rotational motion of the second transmission rod 342 into the linear motion of the second slide 33. The second slide 33 can move relative to the filter plate 21 along the axial direction (i.e., the first direction Z) of the second transmission rod 342 under the transmission connection of the second transmission rod 342.
[0109] The second lifting mechanism 34 can drive the second slide 33 to move in the first direction Z, thereby driving the first clamping mechanism 31 to move relative to the filter press plate 21 in the first direction Z. The first clamping mechanism 31 moves flexibly and the driving method is simple and reliable. When the second lifting mechanism 34 is used to clamp the inner tube 2001 of the flash filter bottle, the second lifting mechanism 34 can drive the second slide 33 to move towards the inner tube 2001 of the flash filter bottle in the first direction Z, so that the first clamping mechanism 31 approaches and clamps the inner tube 2001 of the flash filter bottle; when the movable plate 12 moves in the first direction Z to drive the filter press plate 21 to press the inner tube 2001 of the flash filter bottle into the outer tube 2002 of the flash filter bottle, the second lifting mechanism 34 can drive the first clamping mechanism 31 to move in the first direction Z and away from the inner tube 2001 of the flash filter bottle, so as to avoid interference between the first clamping mechanism 31 and the inner tube 2001 of the flash filter bottle.
[0110] The first clamping component 30 is disposed on the filter press component 20, which enables both to move synchronously along the first direction and synchronously along the second direction, simplifying the driving method, improving the integration of the device, and making the space occupied by the device small.
[0111] In another embodiment, please refer to Figures 17 and 18. The support assembly 10 includes a support frame 16 and a first lifting mechanism 14 disposed on the support frame 16. The first lifting mechanism 14 is connected to the filter press plate 21 and is used to drive the filter press plate 21 to move along the first direction Z.
[0112] The support frame 16 can be an integral structure or a split structure, and there is no specific limitation. The first lifting mechanism 14 includes a first lifting drive component 141 and a first transmission rod 142. The first transmission rod 142 is connected to the filter press plate 21 and extends along the first direction Z.
[0113] Optionally, the transmission method of the first lifting drive component 141 and the first transmission rod 142 can be referred to the above and will not be repeated.
[0114] Optionally, the support frame 16 includes a first plate 161 and a second plate 162, with the second plate 162 connected to one end of the first plate 161. The cross-section of the support frame 16 is approximately "L"-shaped. The first plate 161 extends along a first direction Z, and a first lifting drive member 141 is disposed on the second plate 162. Optionally, the first plate 161 is provided with a first guide rail 163, which extends along the first direction Z. The filter press plate 21 is also slidably connected to the first guide rail 163 and is used to move relative to the first guide rail 163 along the first direction Z under the drive of the first lifting mechanism 14.
[0115] By setting the first lifting mechanism 14, the first lifting mechanism 14 drives the filter plate 21 to move along the first direction Z, which has high transmission efficiency and the transmission method can be selected according to the actual product needs.
[0116] In one embodiment, as shown in Figures 17 and 18, the first clamping mechanism 31 is slidably connected to the filter press plate 21 and is movable along the second direction X. The filter press assembly 20 also includes a first translation mechanism 22, which is disposed on the filter press plate 21, connected to the first clamping mechanism 31, and used to drive the first clamping mechanism 31 to move along the second direction X.
[0117] The first translation mechanism 22 and the filter plate 21 can be directly or indirectly connected, without restriction. When the first lifting mechanism 14 drives the filter plate 21 to move in the first direction Z, the first clamping mechanism 31 and the first translation mechanism 22 move synchronously with the filter plate 21 in the first direction Z.
[0118] Optionally, the filter press plate 21 is provided with a second guide slide rail 24, which extends along the second direction X. The first tube clamping mechanism 31 is also slidably connected to the second guide slide rail 24 and is used to move relative to the second guide slide rail 24 along the second direction X under the drive of the first translation mechanism 22.
[0119] The structure of the first translation mechanism 22 is similar to that described above, and can be referred to accordingly without further explanation.
[0120] The filter press assembly 20 also includes a first translation mechanism 22, which is located on the filter press plate 21 and is used to drive the first clamping mechanism 31 to move along the second direction X. This allows the first clamping mechanism 31 to move in the second direction X. The first clamping mechanism 31 can accurately move to a designated position and clamp the inner tube 2001 and / or the outer tube 2002 of the flash filter bottle, making it convenient to flexibly operate the flash filter bottle in different positions and ensuring high experimental accuracy.
[0121] Optionally, the first translation mechanism 22 is also used to drive the first clamping mechanism 31 to move along a third direction Y, so as to further expand the range of motion of the first clamping mechanism 31.
[0122] In one embodiment, as shown in FIG3, the filter press assembly 20 further includes a pressure sensor 145, which is disposed on the movable plate 12 and is used to abut against the first lifting mechanism 14 to obtain pressure data; or, the pressure sensor 145 is disposed on the first lifting mechanism 14 and is used to abut against the movable plate 12 to obtain pressure data; wherein, the pressure data is used to characterize the moving distance of the filter press plate 21 along the first direction Z.
[0123] The pressure sensor 145 is used to sense pressure signals and convert them into usable output electrical signals according to a certain rule. Optionally, the pressure sensor 145 can be a piezoresistive sensor, a capacitive sensor, a piezoelectric sensor, an electromagnetic sensor, etc., or any pressure sensor feasible in the art, without specific limitations.
[0124] Optionally, the pressure sensor 145 can move relative to the first lifting mechanism 14 and / or the movable plate 12 along the first direction Z. When the filter plate 21 moves along the first direction Z and abuts against the inner tube 2001 of the flash filter bottle, the pressure sensor 145 abuts against the first lifting mechanism 14 and / or the movable plate 12. At this time, the pressure sensor 145 can measure the pressure data of the abutment. This pressure data will change with the different moving distance of the filter plate 21 along the first direction Z. According to the change of pressure data, the pressing depth of the filter plate 21 during filtration can be precisely controlled.
[0125] The filter press assembly 20 also includes a pressure sensor 145. The pressure data measured by the pressure sensor 145 can characterize the moving distance of the filter press plate 21 along the first direction Z. This allows for precise control of the pressing depth of the filter press plate 21 during filtration, preventing insufficient pressing of the filter press plate 21 that would result in the inner tube 2001 of the flash filter bottle not being fully pressed into the outer tube 2002 of the flash filter bottle, leading to poor filtration. It also prevents excessive pressing of the filter press plate 21 that would cause excessive stress on the inner tube 2001 and the outer tube 2002 of the flash filter bottle, resulting in damage.
[0126] In one embodiment, as shown in Figures 2 and 3, the first lifting mechanism 14 further includes a first floating joint 143 and a second floating joint 144. The first floating joint 143 is connected to the first transmission rod 142, and the second floating joint 144 is fixedly connected to the movable plate 12 and movably connected to the first transmission rod 142. A pressure sensor 145 is disposed on the second floating joint 144 and located between the first floating joint 143 and the second floating joint 144. The pressure sensor 145 is used to abut against the first floating joint 143 to obtain pressure data.
[0127] Optionally, the first floating joint 143 is fixedly connected to the end of the first transmission rod 142 away from the first lifting drive member 141, and the second floating joint 144 is sleeved on the first transmission rod 142 and fixedly connected to the movable plate 12. The second floating joint 144 is generally cylindrical, and both the first floating joint 143 and the pressure sensor 145 are housed within the second floating joint 144. The first floating joint 143 and the second floating joint 144 are movable relative to each other, such that the end of the first floating joint 143 near the first transmission rod 142 can abut against the end of the second floating joint 144 away from the movable plate 12. The pressure sensor 145 is fixedly connected to the second floating joint 144, and the first floating joint 143 can move relative to the pressure sensor 145 and the second floating joint 144 in the first direction Z, thereby driving the movable plate 12 to move, and the first floating joint 143 can abut against the pressure sensor 145 to obtain pressure data. Alternatively, the pressure sensor 145 is fixedly connected to the first floating joint 143, and the first floating joint 143 and the pressure sensor 145 can move relative to the second floating joint 144 along the first direction Z, so that the pressure sensor 145 can abut against the second floating joint 144 or the movable plate 12 to obtain pressure data.
[0128] In one embodiment, a pressure sensor 145 is disposed on the second floating joint 144 and opposite to the first floating joint 143. When the first lifting drive member 141 drives the first transmission rod 142 to move the first floating joint 143 upward, the first floating joint 143 moves the second floating joint 144 and the movable plate 12 upward together. At this time, the first floating joint 143 and the pressure sensor 145 are spaced apart. When the first lifting drive member 141 drives the first transmission rod 142 to move the first floating joint 143 downward, the first floating joint 143 abuts against the pressure sensor 145, and the pressure data detected by the pressure sensor 145 increases. Subsequently, the pressure sensor 145 moves the second floating joint 144 and the movable plate 12 downward together. When the pressure data detected by the pressure sensor 145 reaches a specified value, it indicates that the pressing depth of the filter plate 21 is sufficient. At this time, the pressing can be stopped to avoid insufficient or excessive pressing depth of the filter plate 21, thus ensuring the filtration effect.
[0129] The first lifting mechanism 14 includes a first lifting drive 141, a first transmission rod 142, a first floating joint 143, and a second floating joint 144. The first lifting drive 141 drives the first transmission rod 142 to move the first floating joint 143 in the first direction Z, which in turn drives the second floating joint 144 and the movable plate 12 to move in the first direction Z. The transmission method is simple and efficient. During the pressing process, the first floating joint 143 can abut against the pressure sensor 145. The pressure sensor 145 can obtain pressure data based on the abutment force. Based on the change of pressure data, the pressing depth of the filter plate 21 during filtration can be accurately controlled.
[0130] In one embodiment, as shown in FIG4, the first clamping mechanism 31 includes a first clamping drive 311, a first clamping part 312 and a second clamping part 313. The first clamping drive 311 is disposed on the second slide 33. At least one of the first clamping part 312 and the second clamping part 313 is connected to the first clamping drive 311, and the first clamping drive 311 is used to cause the first clamping part 312 and the second clamping part 313 to move relative to each other to clamp the inner tube 2001 of the flash filter bottle.
[0131] The first clamping part 312 can be a one-piece structure manufactured using a molding process, or it can be a separate structure. The various parts of the first clamping part 312 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation. Similarly, the structure of the second clamping part 313 can be referred to the first clamping part 312 described above, and will not be repeated.
[0132] Optionally, at least one of the first clamping part 312 and the second clamping part 313 is slidably connected to the second slide 33 so as to move relative to each other under the drive of the first clamping drive 311. When the first clamping part 312 and the second clamping part 313 move relative to each other, they can be used to clamp a single flash filter bottle inner tube 2001 or multiple flash filter bottle inner tubes 2001, without limitation.
[0133] Optionally, when the first clamping part 312 and the second clamping part 313 move toward each other, the first clamping mechanism 31 clamps the inner tube 2001 of the flash filter bottle; when the first clamping part 312 and the second clamping part 313 move away from each other, the first clamping mechanism 31 releases the inner tube 2001 of the flash filter bottle. Alternatively, when the first clamping part 312 and the second clamping part 313 move away from each other, the first clamping mechanism 31 clamps the inner tube 2001 of the flash filter bottle; when the first clamping part 312 and the second clamping part 313 move toward each other, the first clamping mechanism 31 releases the inner tube 2001 of the flash filter bottle. No restriction is imposed.
[0134] By setting the first clamping mechanism 31, the inner tube 2001 of the flash filter bottle can be clamped and moved to a designated position, which is simple to operate.
[0135] In one embodiment, as shown in FIG4, the first clamping part 312 includes a first mounting plate 3121 and multiple sets of first fingers 3122, the multiple sets of first fingers 3122 being spaced apart on the first mounting plate 3121, each set of first fingers 3122 including at least one first finger 3122; the second clamping part 313 includes a second mounting plate 3131 and multiple sets of second fingers 3132, the multiple sets of second fingers 3132 being spaced apart on the second mounting plate 3131, each set of second fingers 3132 including at least one second finger 3132; the multiple sets of first fingers 3122 and the multiple sets of second fingers 3132 correspond one-to-one, the first fingers 3122 and the second fingers 3132 are used to move relative to each other to clamp the inner tube 2001 of the flash filter bottle.
[0136] Optionally, both the first mounting plate 3121 and the second mounting plate 3131 are generally L-shaped. The first mounting plate 3121 includes a first sub-plate (not shown) and a second sub-plate (not shown) connected together. The second mounting plate 3131 includes a third sub-plate (not shown) and a fourth sub-plate (not shown) connected together. The second sub-plate is connected to one end of the first sub-plate, and the fourth sub-plate is connected to the end of the third sub-plate away from the second sub-plate. The first and third sub-plates extend in the same direction, and the second and fourth sub-plates extend in the same direction. The extension direction of the first sub-plate can be a second direction X, or it can intersect with the second direction X (such as a third direction Y), without limitation. For example, the first and third sub-plates both extend along a third direction, and the second and fourth sub-plates both extend along a second direction. The second and fourth sub-plates are used to limit the relative movement of the first and third sub-plates.
[0137] At least one of the first mounting plate 3121 and the second mounting plate 3131 is connected to the first clamping drive member 311. Optionally, both the first sub-plate and the third sub-plate extend along a third direction, with multiple sets of first fingers 3122 spaced apart on the first sub-plate and multiple sets of second fingers 3132 spaced apart on the third sub-plate, and the first clamping drive member 311 causes the first mounting plate 3121 and the second mounting plate 3131 to move toward each other along a third direction.
[0138] The structure of the first finger 3122 and the second finger 3132 can be the same or similar, such as the first finger 3122 and the second finger 3132 being cylindrical, rod-shaped, V-shaped, arc-shaped, etc., without restriction.
[0139] Optionally, the first finger 3122 is approximately L-shaped, with the shorter side of the L-shape connected and fixed to the first mounting plate 3121, and the longer side extending approximately along the first direction Z, to increase the contact area between the first finger 3122 and the inner tube 2001 of the flash filter bottle, thereby increasing the clamping stability. Multiple first fingers 3122 in each group are spaced apart, and the spacing between multiple groups of first fingers 3122 is approximately the same. In one specific embodiment, there are four groups of first fingers 3122, spaced apart along a third direction. Each group of first fingers 3122 includes two first fingers 3122, which are spaced apart along the second direction X. By setting multiple sets of first fingers 3122 and second fingers 3132, multiple flash filter inner tubes 2001 can be clamped and transported simultaneously to improve experimental throughput and efficiency.
[0140] Similarly, the setting method for the second finger 3132 is similar to that of the first finger 3122, so you can refer to it and will not repeat it here.
[0141] In one specific embodiment, when the first finger 3122 and the second finger 3132 move towards each other, the first clamping mechanism 31 clamps the inner tube 2001 of the flash filter bottle; when the first finger 3122 and the second finger 3132 move away from each other, the first clamping mechanism 31 releases the inner tube 2001 of the flash filter bottle. During operation, the first clamping mechanism 31 moves along the first direction Z under the drive of the first lifting mechanism 14 or the second lifting mechanism 34, positioning the first finger 3122 and the second finger 3132 on both sides of the inner tube 2001 of the flash filter bottle. Then, the first clamping drive member 311 causes the first clamping part 312 and the second clamping part 313 to move relative to each other, reducing the distance between the first finger 3122 and the second finger 3132 until both the first finger 3122 and the second finger 3132 are in contact with the wall of the inner tube 2001 of the flash filter bottle, completing the clamping action of the first clamping mechanism 31. Subsequently, the first translation mechanism 22 drives the first slide 23 to move along the second direction X, which in turn drives the first clamping mechanism 31 to move along the second direction X until the inner tube 2001 of the flash filter bottle, held between the first finger 3122 and the second finger 3132, moves above the outer tube 2002 of the flash filter bottle. At this time, the distance between the inner tube 2001 and the outer tube 2002 of the flash filter bottle can be adjusted by the first lifting mechanism 14 or the second lifting mechanism 34 driving the first clamping mechanism 31, so that the inner tube 2001 of the flash filter bottle partially extends into the outer tube 2002 of the flash filter bottle, preventing the inner tube 2001 of the flash filter bottle from falling out of the outer tube 2002 of the flash filter bottle after the first clamping mechanism 31 is released. After adjustment, the first clamping drive 311 causes the first clamping part 312 and the second clamping part 313 to move relative to each other, and the first finger 3122 and the second finger 3132 move away from each other to release the inner tube 2001 of the flash filter bottle, thus completing the movement and placement of the inner tube 2001 of the flash filter bottle.
[0142] By setting the first clamping part 312 and the second clamping part 313, the first clamping mechanism 31 can clamp and move multiple flash filter inner tubes 2001 simultaneously, resulting in high experimental efficiency. Furthermore, the multiple sets of first fingers 3122 and multiple sets of second fingers 3132 move the same distance, preventing errors in the moving distance and improving the accuracy of batch operations.
[0143] In one embodiment, as shown in FIG4, the first clamping mechanism 31 further includes a first transmission member 314 and a second transmission member (not shown in the figure), a first clamping drive member 311 is connected to the first transmission member 314 and the second transmission member respectively, the first transmission member 314 is connected and fixed to the first clamping part 312, the second transmission member is connected and fixed to the second clamping part 313, and the first clamping drive member 311 is used to drive the first transmission member 314 and the second transmission member to move in opposite directions; at least one of the first transmission member 314 and the second transmission member includes a rack.
[0144] The connection between the first transmission member 314 and the first clamping part 312 can be achieved through welding, bonding, snap-fitting, screwing, riveting, or other methods, without limitation. Optionally, the first transmission member 314 is connected to the surface of the first mounting plate 3121 facing away from the first finger 3122. Optionally, the first clamping drive member 311 drives the first transmission member 314 to move, thereby moving the first clamping part 312; or, the first clamping drive member 311 can also drive the first transmission member 314 to rotate, thereby moving the first clamping part 312, without limitation. The connection method between the second transmission member and the second clamping part 313 can refer to that between the first transmission member 314 and the first clamping part 312, without specific limitations.
[0145] Optionally, at least one of the first transmission component 314 and the second transmission component may be a single rack, or a rack group formed by the meshing of multiple racks, or a rack plus other transmission structures (such as gears, etc.), without any specific limitations.
[0146] In one specific embodiment, as shown in FIG4, the first clamping drive 311 is a motor, and the first clamping mechanism 31 further includes a transmission gear (not shown in the figure), which is connected to the first clamping drive 311 and rotates under the drive of the first clamping drive 311. The first transmission member 314 and the second transmission member are both racks and pinions, and mesh with the transmission gear respectively. When the first clamping drive 311 drives the transmission gear to rotate, the first transmission member 314 and the second transmission member respectively drive the first clamping part 312 and the second clamping part 313 to move in opposite directions to clamp or release the inner tube 2001 of the flash filter bottle. In addition, in order to ensure the movement stability of the first clamping part 312 and the second clamping part 313, a guide structure (such as a slide rail) can be added to guide the movement of the first clamping part 312 and the second clamping part 313.
[0147] The first clamping mechanism 31 also includes a first transmission component 314 and a second transmission component. The first clamping drive component 311 is used to drive the first transmission component 314 and the second transmission component to move in opposite directions, and to drive the first clamping part 312 and the second clamping part 313 to move relative to each other. The transmission method is simple and reliable.
[0148] In one embodiment, as shown in Figures 1 and 2, the flash filtration device 100 further includes a liquid addition assembly 40, which is connected to the pressure filtration assembly 20 and used to add sample solution or diluent to the outer tube 2002 of the flash filtration bottle. The liquid addition assembly 40 includes a liquid addition needle 41 and a liquid addition pump 42. The liquid addition needle 41 is connected to the pressure filtration plate 21, and the liquid addition pump 42 is connected to the liquid addition needle 41 and used to output sample solution or diluent to the liquid addition needle 41.
[0149] The liquid addition needle 41 is used to add a fixed volume of liquid into the container. Optionally, the liquid addition needle 41 is used to add sample solution or diluent into the outer tube 2002 of the flash filtration flask. The liquid addition needle 41 can be a fixed-volume liquid phase addition needle or an adjustable-volume liquid phase addition needle, or any other feasible liquid addition needle 41 in the art, without limitation. The liquid addition needle 41 can meet the high-precision sample addition requirements in small-volume liquid operations, significantly reducing the errors caused by manual liquid addition, thereby improving the accuracy and reliability of the experiment.
[0150] Optionally, the number of liquid dosing needles 41 can be one or more, without limitation. When there are multiple liquid dosing needles 41, multiple liquid dosing needles 41 can simultaneously deliver the same liquid into different flash filter flask inner tubes 2001, or deliver different liquids into different flash filter flask inner tubes 2001, without limitation. Optionally, the number of liquid dosing needles 41 corresponds to the number of the first clamping mechanism 31, allowing operation on flash filter flasks of the same batch. In a specific embodiment, four liquid dosing needles 41 are spaced apart to improve experimental throughput and efficiency. The liquid dosing needles 41 can be positioned at the edge of the filter press plate 21 to minimize interference between components.
[0151] Optionally, the liquid injection needle 41 is directly connected and fixed to the filter press plate 21; or, as shown in Figure 1, the liquid injection assembly 40 also includes a liquid injection needle mounting base 43, which is connected and fixed to the filter press plate 21, and the liquid injection needle 41 is installed on the liquid injection needle mounting base 43 and extends toward the side opposite to the top plate 13.
[0152] The liquid delivery pump 42 is used to deliver liquid, such as sample solution, diluent, or cleaning solution, into the liquid delivery needle 41. The liquid delivery pump 42 can be disposed on the support assembly 10; specifically, it can be disposed on the top plate 13, the support column 11, or other parts of the support assembly 10, without limitation. Optionally, the liquid delivery pump 42 can be a plunger pump, diaphragm pump, peristaltic pump, piston pump, or any feasible liquid delivery device in the art, without limitation.
[0153] Optionally, there can be one or more liquid pumps 42, without any specific limitation. When there are multiple liquid pumps 42, they can simultaneously deliver the same liquid to multiple liquid injection needles 41, or they can deliver different liquids to one or more liquid injection needles 41 respectively. The choice can be made according to actual needs, without any limitation.
[0154] By setting up the above-mentioned liquid addition component 40, sample liquid or diluent can be added to the outer tube 2002 of the flash filter bottle without manual operation, which can meet the high-precision sample addition requirements in liquid operation, and also improve experimental efficiency and experimental safety.
[0155] In one embodiment, as shown in Figures 1 and 2, the liquid addition assembly 40 further includes a cleaning mechanism 44, which includes a cleaning tank 441 and a cleaning pump 442, with the cleaning pump 442 connected to the cleaning tank 441.
[0156] The cleaning tank 441 is used to accommodate at least a portion of the dosing needle 41 and to hold the cleaning waste liquid. Optionally, the cleaning tank 441 is connected and fixed to the support assembly 10; the connection method can be direct or indirect, without limitation. The cleaning pump 442 is used to discharge the cleaning waste liquid from the cleaning tank 441. Optionally, the cleaning pump 442 can be a plunger pump, diaphragm pump, peristaltic pump, piston pump, etc., without limitation.
[0157] In one specific embodiment, as shown in FIG1, the cleaning mechanism 44 further includes a cleaning tank mounting bracket 443, which is connected and fixed to the support assembly 10. The cleaning tank mounting bracket 443 is used to install the cleaning tank 441, and the cleaning tank 441 is located near the end of the support column 11 away from the top plate 13. This avoids interference between the cleaning tank 441 and other parts of the filter press assembly 20, and also facilitates the insertion of the liquid dosing needle 41 into the cleaning tank 441. The cleaning pump 442 is connected to and adjacent to the cleaning tank 441, facilitating the timely discharge of cleaning waste liquid from the cleaning tank 441.
[0158] When adding different sample solutions or diluents into the outer tube 2002 of the flash filter bottle using the dispensing needle 41, to avoid contamination of the subsequent liquid by the previous liquid, the dispensing needle 41 needs to be cleaned before adding the next liquid. For example, if diluent B is added to sample solution A in the first experiment, and diluent D is added to sample solution C in the second experiment, the dispensing needle 41 is inserted into the cleaning tank 441 before adding diluent D. The dispensing pump 42 pumps diluent D into the dispensing needle 41, which flushes the residual diluent B in the tubing and on the inner wall of the dispensing needle 41. The flushing solution accumulates in the cleaning tank 441, thus simultaneously cleaning the outer wall of the dispensing needle 41. Afterward, the cleaning pump 442 removes the cleaning waste liquid from the cleaning tank 441, completing the waste liquid discharge.
[0159] By setting up the cleaning mechanism 44, the inner and outer walls of the liquid addition needle 41 can be cleaned. After cleaning, the cleaning pump 442 can discharge the cleaning waste liquid in the cleaning tank 441, avoiding cross-contamination when adding different sample liquids or diluents to the liquid addition needle 41, and ensuring the accuracy of the experiment.
[0160] In one embodiment, as shown in Figures 5 to 7, the flash filtration device 100 further includes a flash filtration bottle transfer assembly 50, which includes a flash filtration bottle tray placement seat 51 for holding the inner tube 2001 and / or the outer tube 2002 of the flash filtration bottle.
[0161] The flash filter flask tray holder 51 is used to hold flash filter flask trays, which contain multiple inner tubes 2001 and / or outer tubes 2002 of flash filter flasks, facilitating batch processing of the entire tray of inner tubes 2001 and / or outer tubes 2002. The flash filter flask tray holder 51 can be roughly rectangular, square, trapezoidal, etc., and its shape can correspond to the shape of the flash filter flask tray; there are no restrictions.
[0162] Optionally, the flash filter flask tray can be of different sizes to hold different numbers of flash filter flask inner tubes 2001 and / or flash filter flask outer tubes 2002. For example, as shown in Figures 5 and 17, the flash filter flask tray can hold 48 flash filter flask inner tubes 2001 or flash filter flask outer tubes 2002, or, as shown in Figure 18, the flash filter flask tray can hold 12 flash filter flask inner tubes 2001 or flash filter flask outer tubes 2002.
[0163] Optionally, the flash flask tray holder 51 is used to hold a single flash flask tray, with multiple inner tubes 2001 and multiple outer tubes 2002 of flash flasks arranged in a multi-row, multi-column array within the flash flask tray. Optionally, the inner tubes 2001 and outer tubes 2002 of flash flasks are arranged alternately in the column direction, where the second direction X is the column direction of the array distribution of multiple flash flasks. That is, in the second direction X, one row is the inner tubes 2001, the next row is the outer tubes 2002, and the next row is the inner tubes 2001, and so on. Alternatively, the flash flask tray holder 51 is used to hold two flash flask trays, one for holding the inner tubes 2001 and the other for holding the outer tubes 2002. Alternatively, the inner tubes 2001 and outer tubes 2002 can also be placed in any other feasible manner without limitation.
[0164] By setting up the flash filter bottle transfer assembly 50, the inner tube 2001 and outer tube 2002 of the flash filter bottle can be filled in batches, which facilitates the batch experimental operation of the filter press assembly 20 and the first clamping assembly 30, improves experimental efficiency, and meets the requirements of high-throughput experimental processing.
[0165] In one embodiment, as shown in FIG5, the flash filter bottle tray placement seat 51 includes a first tray placement seat 511 and a second tray placement seat 512, the first tray placement seat 511 and the second tray placement seat 512 being arranged along a second direction X.
[0166] The first tray placement seat 511 and the second tray placement seat 512 are spaced apart in the first direction Z, and the first tray placement seat 511 is closer to the filter plate 21 in the first direction Z than the second tray placement seat 512.
[0167] The first pallet holder 511 and the second pallet holder 512 are arranged adjacent to each other along the second direction X, and may or may not be connected. Optionally, the first pallet holder 511 and the second pallet holder 512 may be an integral structure or a separate structure. The first pallet holder 511 and the second pallet holder 512 may be connected and fixed by means of welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0168] Optionally, the flash filter bottle tray holder 51 further includes a connecting plate 513. One end of the connecting plate 513 in the first direction Z is connected to the first tray holder 511, and the other end is connected to the second tray holder 512. The first tray holder 511 and the second tray holder 512 are located on opposite sides of the connecting plate 513, that is, the first tray holder 511, the connecting plate 513, and the second tray holder 512 can be approximately "Z" shaped. Optionally, the connecting plate 513 is approximately parallel to the first direction Z.
[0169] One of the first tray placement seat 511 and the second tray placement seat 512 is used to hold the inner tube 2001 of the flash filter bottle, and the other is used to hold the outer tube 2002 of the flash filter bottle. Optionally, the first tray placement seat 511 is used to hold the inner tube 2001 of the flash filter bottle, and the second tray placement seat 512 is used to hold the outer tube 2002 of the flash filter bottle; or, as shown in Figure 5, the first tray placement seat 511 is used to hold the outer tube 2002 of the flash filter bottle, and the second tray placement seat 512 is used to hold the inner tube 2001 of the flash filter bottle, without limitation. Optionally, there are multiple inner tubes 2001 and multiple outer tubes 2002 of the flash filter bottle, and the number and arrangement of the outer tubes 2002 of the flash filter bottle on the first tray placement seat 511 and the inner tubes 2001 of the flash filter bottle on the second tray placement seat 512 are corresponding.
[0170] With this setup, the distance between the inner tube 2001 and the outer tube 2002 of the flash filtration bottle in the same batch of operations is equal in the second direction X. That is, during the process of the flash filtration device 100 moving in the second direction X and placing the inner tube 2001 of the flash filtration bottle into the outer tube 2002 of the flash filtration bottle in stages, the distance that the first slide 23 moves in the second direction X each time does not need to be adjusted again, which can improve experimental efficiency.
[0171] The flash filter bottle tray placement seat 51 can be fixed in place or moved along the second direction X and / or the third direction Y. When the flash filter bottle tray placement seat 51 moves, the flexibility of the flash filter device 100 can be improved and the flash filter bottle transfer time can be shortened.
[0172] In one embodiment, as shown in Figures 17 and 18, the filter press plate 21 and the first clamping mechanism 31 are spaced apart along the third direction Y. The flash filter bottle tray placement seat 51 includes a first tray placement seat 511 and a second tray placement seat 512, which are arranged along the third direction Y. This arrangement allows the first tray placement seat 511 and the second tray placement seat 512 to move along the third direction Y to be located below the filter press plate 21 or the first clamping mechanism 31, and facilitates the first clamping mechanism 31 in clamping different flash filter bottles in the second direction X.
[0173] In one embodiment, as shown in Figures 5 to 7, the flash filter bottle transfer assembly 50 further includes a first moving mechanism 52, which is connected to the flash filter bottle tray placement seat 51 and is used to move the flash filter bottle tray placement seat 51 along the second direction X and / or the third direction Y. The third direction Y intersects both the first direction Z and the second direction X; preferably, the third direction Y is perpendicular to both the first direction Z and the second direction X.
[0174] Optionally, at least one of the first tray placement seat 511 and the second tray placement seat 512 is connected to the first moving mechanism 52, which can drive the first tray placement seat 511 and the second tray placement seat 512 to move synchronously. When the first tray placement seat 511 and the second tray placement seat 512 are connected, the first moving mechanism 52 can be connected to either the first tray placement seat 511 or the second tray placement seat 512; when the first tray placement seat 511 and the second tray placement seat 512 are not connected, the first moving mechanism 52 can be connected to both the first tray placement seat 511 and the second tray placement seat 512. For example, as shown in FIG5, the first tray placement seat 511 is connected to the second tray placement seat 512, and the first moving mechanism 52 is connected to the first tray placement seat 511, driving the first tray placement seat 511 to move, thereby causing the second tray placement seat 512 to move synchronously.
[0175] In one embodiment, as shown in FIG18, the flash filtration device 100 further includes a baffle 54, which is disposed on the support assembly 10 and spaced apart from the flash filtration bottle tray placement seat 51 in the first direction Z. The baffle 54 has a through hole 541 along the first direction Z. The diameter of the through hole 541 is smaller than the outer diameter of the inner tube 2001 of the flash filtration bottle (such as the outer diameter of the tube cap). The flash filtration bottle tray placement seat 51 can be moved to the baffle 54 under the drive of the first moving mechanism 52.
[0176] Optionally, the baffle 54 can be connected and fixed to the support column 11 or support frame 16 of the support assembly 10. The connection method between the baffle 54 and the support assembly 10 can be welding, bonding, snap-fitting, screwing, riveting, magnetic connection, etc., without limitation. The shape of the baffle 54 is not limited, and can be rectangular, square, circular, regular polygonal, etc.
[0177] Optionally, the number of through holes 541 can be one or more, without limitation. Optionally, the number of through holes 541 is the same as the number of flash filter inner tubes 2001 held in the flash filter tray on the flash filter tray placement seat 51, and when the flash filter tray placement seat 51 moves to the baffle 54 and aligns with the baffle 54, the through holes 541 fall into the orthographic projection of the flash filter inner tube 2001 on the baffle 54.
[0178] After filtration is complete, the filtrate can be extracted from the inner tube 2001 of the flash filter bottle. In one embodiment, as shown in FIG18, the first moving mechanism 52 can drive the flash filter bottle tray placement seat 51 to move along the third direction Y. When it is necessary to sample the filtrate, the flash filter bottle tray placement seat 51 can be moved to the baffle 54 under the drive of the first moving mechanism 52, and the sample can be taken using the pipetting assembly 60 (such as a puncture needle). By setting the baffle 54, the baffle 54 can prevent the inner tube 2001 of the flash filter bottle from being lifted up by the pipetting assembly 60 after sampling.
[0179] Please refer to Figures 6 and 7. This application embodiment also provides an experimental platform 1000, including a base 200 and a flash filter device 100 in this application embodiment. The support component 10 of the flash filter device 100 is mounted on the base 200.
[0180] The base 200 supports the various modules of the experimental platform 1000. The base 200 can be made of a material with high structural strength, specifically metal, high-strength plastic, ceramic, etc. Metal materials include aluminum, aluminum alloy, magnesium alloy, iron, and iron alloys. Optionally, the base 200 can consist of a mounting base plate, bottom sheet metal, chassis support columns, and a bottom cover plate. Front and rear handles, the main screen, power supply, and various driver boards can be mounted on the base 200.
[0181] The base 200 can be a one-piece structure, meaning it is manufactured using a single molding process, such as stamping or casting, without limitation. Alternatively, the base 200 can be a modular structure, with its components connected and secured by welding, bonding, snap-fitting, screwing, riveting, or other methods. The base 200 can also utilize any other feasible support structure found in the art, without specific limitations.
[0182] Optionally, the support column 11 of the support component 10 is connected and fixed to the base 200. The connection method can be welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0183] The experimental platform 1000 is equipped with multiple workstations, such as the flash filtration workstation where the flash filtration device 100 works as mentioned above. The experimental platform 1000 also includes a pipetting workstation, a cap opening workstation, and so on. The workstations are arranged in an orderly manner on the experimental platform 1000, which can reduce the transportation and waiting time between each workstation and make the flow between different workstations more convenient.
[0184] Optionally, the experimental platform 1000 also includes a controller (not shown), which serves as the control center of the entire experimental platform 1000. The controller is used to issue working instructions to the corresponding modules in a timely manner to achieve collaborative work between the modules. For example, the controller can be one or more of a PLC, a microcontroller, or computer control software. Optionally, the controller is located on the base 200.
[0185] The experimental platform 1000 in this embodiment of the application, by setting a base 200 and a flash filter device 100 in this embodiment of the application, with the flash filter device 100 installed on the base 200, has a high degree of overall integration and is easy to operate. It can improve experimental efficiency, reduce pollution that may be caused by manual operation, reduce experimental errors, and improve experimental safety.
[0186] In one embodiment, as shown in Figures 5 to 7, the flash filter bottle transfer assembly 50 includes a flash filter bottle tray placement seat 51 and a first moving mechanism 52. The flash filter bottle tray placement seat 51 is slidably connected to the base 200 and can move along a second direction X and / or a third direction Y. The first moving mechanism 52 is disposed on the base 200 and connected to the flash filter bottle tray placement seat 51. The first moving mechanism 52 is used to drive the flash filter bottle tray placement seat 51 to move relative to the base 200. The flash filter bottle tray placement seat 51 is used to hold the inner tube 2001 and the outer tube 2002 of the flash filter bottle.
[0187] Optionally, the flash filter bottle transfer assembly 50 also includes a mounting base 53, which is connected and fixed to the base 200. The flash filter bottle tray placement seat 51 can move relative to the mounting base 53 in a third direction Y. The first moving mechanism 52 and the flash filter bottle tray placement seat 51 are both located on the mounting base 53, which facilitates the overall installation and handling of the flash filter bottle transfer assembly 50.
[0188] The first moving mechanism 52 can be any feasible drive transmission structure in the art. Optionally, the first moving mechanism 52 includes a first moving drive component 521, which is disposed on the mounting base 53. The first moving drive component 521 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation.
[0189] Optionally, the mounting base 53 has a sliding guide rail 531 on the surface facing away from the base 200. The flash filter bottle tray placement seat 51 can be slidably connected to the sliding guide rail 531 by a slider and can move relative to the sliding guide rail 531 in the third direction Y.
[0190] Optionally, the first moving drive 521 can be a linear motor, and the first moving mechanism 52 further includes a second transmission part 522. The second transmission part 522 includes a lead screw and nut pair, the lead screw being connected to the drive shaft of the first moving drive 521 via a coupling, and the nut being connected to the flash filter bottle tray placement seat 51. Optionally, the lead screw of the second transmission part 522 extends along a third direction Y. The first moving drive 521 drives the lead screw to rotate, causing the nut to move linearly along the lead screw, thereby driving the flash filter bottle tray placement seat 51 to move along a third direction Y on the mounting base 53.
[0191] Optionally, at least one of the first tray placement seat 511 and the second tray placement seat 512 is connected to the first moving mechanism 52, which can drive the first tray placement seat 511 and the second tray placement seat 512 to move synchronously. For details, please refer to the foregoing related content, which will not be repeated here.
[0192] The flash filtration bottle transfer component 50 is set up to drive the flash filtration bottle tray placement seat 51 to move along the third direction Y. This allows the flash filtration bottle tray placement seat 51 to move quickly between different workstations on the experimental platform 1000. Combined with the filter press component 20 and the first clamping component 30 that move along the second direction X, the spatial distance between different operating workstations on the experimental platform 1000 during the experiment can be shortened, and the transportation time between each operation step can be reduced.
[0193] In one embodiment, as shown in Figures 6 to 12, the experimental platform 1000 further includes a sampling device 300, which includes a pipetting assembly 60. The pipetting assembly 60 is used to transfer sample liquid or diluent into the outer tube 2002 of the flash filter bottle, or to extract filtrate from the inner tube 2001 of the flash filter bottle after filtration.
[0194] Optionally, the pipetting assembly 60 includes a pipette mount 61 for mounting a pipette 2003 and transferring the sample solution or diluent into the outer tube 2002 of the flash filtration bottle through the pipette 2003.
[0195] The 2003 pipette tip, also known as a pipette tip or pipette tip, is a disposable pipette tip used in laboratories that can hold a certain volume of liquid. Optionally, the material of the 2003 pipette tip can be selected according to the characteristics of different samples; for example, it can be made of polytetrafluoroethylene, polypropylene, silica gel, glass, quartz, etc., without limitation.
[0196] Optionally, the pipetting assembly 60 can be equipped with a single pipette tip 2003 or multiple pipette tips 2003 simultaneously; there is no specific limitation. Optionally, the pipetting assembly 60 can be equipped with multiple pipette tips 2003 via the pipette tip mounting base 61, allowing simultaneous operation of multiple pipette tips 2003. This enables simultaneous pipetting operations on multiple flash filter bottle outer tubes 2002, meeting high-throughput operation requirements and enabling batch pipetting operations.
[0197] Optionally, the pipetting assembly 60 can move relative to the base 200 along the first direction Z, facilitating the dispensing and aspiration of liquid by the pipette tip 2003. Optionally, the pipetting assembly 60 can also move relative to the base 200 along the second direction X and / or the third direction Y, transferring the sample solution or diluent to different stations to perform different operations on the sample solution or diluent at different stations, reducing manual operation and improving experimental efficiency.
[0198] Optionally, the pipetting assembly 60 also includes a puncture needle (not shown) capable of extracting the filtrate from the inner tube 2001 of the filtered flash filtration flask.
[0199] Optionally, the pipetting assembly 60 also includes a pipetting pump 62, which is connected to the pipetting tip 2003 or the puncture needle and is used to drive the pipetting tip 2003 or the puncture needle to aspirate or dissipate liquid. The pipetting pump 62 can be located in other positions on the top plate 13, the support column 11, or the experimental platform 1000, without specific limitations. Optionally, the pipetting pump 62 can be a plunger pump, diaphragm pump, peristaltic pump, piston pump, etc., or any feasible device for transporting liquids in the art, without specific limitations. Optionally, multiple pipetting pumps 62 can be provided, and the number of pipetting tips 2003 or puncture needles is the same as the number of pipetting pumps 62, with each pipetting pump 62 corresponding to a pipetting tip 2003 or puncture needle in a one-to-one connection. With this configuration, pipetting operations can be performed on multiple flash filtration bottle outer tubes 2002 simultaneously or sampling operations can be performed on multiple flash filtration bottle inner tubes 2001 simultaneously, improving experimental throughput and efficiency.
[0200] For example, the pipetting assembly 60 is used to transfer sample solution into the outer tube 2002 of the flash filtration bottle, and the liquid addition assembly 40 is used to add diluent to the outer tube 2002 of the flash filtration bottle, or vice versa, without limitation.
[0201] By setting up the above-mentioned pipetting assembly 60, the transfer process of sample liquid or diluent can be completed on the experimental platform 1000 without the need to set up an additional liquid transfer platform. The flow between different operation steps is more convenient, which can improve experimental efficiency.
[0202] In one embodiment, as shown in FIG6, the support assembly 10 further includes a side plate 15, which is connected and fixed to the top plate 13 and / or the support column 11. The side plate 15 may extend along a second direction X or a third direction Y.
[0203] The support component 10 can be a one-piece structure, meaning it can be manufactured using a single molding process, such as stamping or casting, without limitation. Alternatively, the support component 10 can be a modular structure, with the side plate 15, top plate 13, and support column 11 connected and fixed by welding, bonding, snap-fitting, screwing, riveting, or other methods. The side plate 15 enhances the overall structural stability of the support component 10 and also serves as the supporting foundation for the sampling device 300. This structural reuse simplifies the structural design and allows for the lightweighting of the experimental platform 1000.
[0204] Referring to Figures 6 to 8, the sampling device 300 further includes a second translation mechanism 301 and a third slide 302. The second translation mechanism 301 is disposed on the side plate 15, and the third slide 302 is slidably connected to the side plate 15 along a second direction X or a third direction Y. The second translation mechanism 301 is connected to the third slide 302 and is used to drive the third slide 302 to move relative to the side plate 15. The pipetting assembly 60 is slidably connected to the third slide 302 and can move relative to the third slide 302 along a first direction Z.
[0205] The shape of the third slide 302 can be block-shaped, plate-shaped, column-shaped, or other irregular shapes, without limitation. Optionally, the third slide 302 is slidably connected to the side plate 15 along the second direction X; the side plate 15 is provided with a second slide rail 151 on the surface facing away from the filter press assembly 20, the second slide rail 151 extends along the second direction X, the third slide 302 is slidably connected to the second slide rail 151, and is used to move relative to the second slide rail 151 along the second direction X under the drive of the second translation mechanism 301, the pipetting assembly 60 is slidably connected to the third slide 302, and is located on the side of the third slide 302 facing away from the second slide rail 151.
[0206] The second translation mechanism 301 can be any feasible drive transmission structure in the art. Optionally, the second translation mechanism 301 includes a second translation drive component 303, which can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation. Optionally, the second translation drive component 303 is disposed on the side plate 15, and the second translation drive component 303 and the side plate 15 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc.
[0207] Optionally, the second translation drive 303 is a linear motor, and the second translation mechanism 301 also includes a third transmission part 304. The third transmission part 304 includes a lead screw and nut pair. The lead screw is connected to the drive shaft of the linear motor through a coupling and extends along the second direction X. The nut is connected to the third slide 302. The linear motor drives the lead screw to rotate, so that the nut moves linearly on the lead screw, thereby driving the third slide 302 to move along the second slide rail 151 relative to the side plate 15 in the second direction X.
[0208] By setting a third slide 302 and a side plate 15 to slide along the second direction X, the pipetting assembly 60 connected to the third slide 302 can move along the second direction X under the action of the third slide 302. The pipetting head 2003 of the pipetting assembly 60 can first draw sample liquid or diluent from other stations. When the third slide 302 moves the pipetting assembly 60 along the second direction X to above the outer tube 2002 of the flash filtration bottle, the pipetting head 2003 can release the drawn sample liquid or diluent into the outer tube 2002 of the flash filtration bottle, realizing the transfer of sample liquid or diluent between different stations. The movement route is convenient, which can improve experimental efficiency and reduce experimental errors. In addition, by integrating the sampling device 300 into one side of the flash filtration device 100, the space volume of the experimental platform 1000 is greatly reduced, achieving lightweighting and miniaturization.
[0209] In one embodiment, as shown in FIG8, the pipetting assembly 60 further includes a fourth slide 63 and a third lifting mechanism 64. The third lifting mechanism 64 is disposed on the third slide 302. The fourth slide 63 is slidably connected to the third slide 302 along the first direction Z, and the pipetting head mounting base 61 is connected to the fourth slide 63. The third lifting mechanism 64 is connected to the fourth slide 63 and is used to drive the fourth slide 63 to move along the first direction Z.
[0210] The shape of the fourth slide 63 can be block-shaped, plate-shaped, column-shaped, or other irregular shapes, without limitation. Optionally, the surface of the third slide 302 facing away from the side plate 15 is provided with a guide rail, and the fourth slide 63 is slidably connected to the guide rail.
[0211] Optionally, the pipette mount 61 is connected and fixed to the fourth slide 63. The connection method can be welding, bonding, snap-fitting, screwing, riveting, etc., without limitation; or, the pipette mount 61 can also be movably connected to the fourth slide 63.
[0212] The third lifting mechanism 64 can be any feasible drive transmission structure in the art. Optionally, the third lifting mechanism 64 includes a third lifting drive member 641 and a third transmission rod (not shown). The third lifting drive member 641 is disposed on the third slide 302, and the third transmission rod extends along the first direction Z and is drively connected to the third lifting drive member 641. Similarly, the third lifting drive member 641 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation. The third lifting drive member 641 can be used to drive the third transmission rod to move along its own axial direction. The third lifting drive member 641 has a drive shaft, and the drive shaft can move linearly when the third lifting drive member 641 is running. The connection method between the third lifting drive member 641 and the third slide 302 can be welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0213] Optionally, the third transmission rod rotates around its own axis under the drive of the third lifting drive 641 and is connected to the fourth slide 63 through a nut. The third transmission rod and the nut form a screw-nut pair, which can convert the rotational motion of the third transmission rod into the linear motion of the fourth slide 63. The fourth slide 63 can move relative to the third slide 302 along the axial direction (i.e., the first direction Z) of the third transmission rod under the transmission connection of the third transmission rod.
[0214] The pipetting assembly 60 also includes a fourth slide 63 and a third lifting mechanism 64. The pipette tip mounting base 61 is connected to the fourth slide 63, and the third lifting mechanism 64 is connected to the fourth slide 63 and drives the fourth slide 63 to move along the first direction Z, thereby driving the pipette tip mounting base 61 to move in the first direction Z. This allows the pipette tip 2003 to be mounted on the pipette tip mounting base 61. The pipette tip 2003 mounted on the pipette tip mounting base 61 can also move downward along the first direction Z to extend into a test tube or other container. When a sample solution or diluent is drawn from a container containing liquid, the pipette tip 2003 can move upward along the first direction Z after the aspiration is completed, avoiding interference with the test tube or other components. Similarly, when the pipette tip 2003 releases liquid into the outer tube 2002 of the flash filter bottle, it can move downward along the first direction Z, allowing the liquid to be directly released into the outer tube 2002 of the flash filter bottle. This avoids potential contamination by impurities when the liquid drips in the air, or splashing outside the outer tube 2002 of the flash filter bottle, thereby reducing experimental errors and improving experimental accuracy.
[0215] In one embodiment, as shown in Figures 8 to 10, the pipetting assembly 60 further includes a first mounting platform 65 and a pitch-changing mechanism 66. There are multiple pipetting head mounting seats 61. The first mounting platform 65 is fixedly connected to the fourth slide 63. The multiple pipetting head mounting seats 61 are all slidably connected to the first mounting platform 65 and can move along the third direction Y. The pitch-changing mechanism 66 is disposed on the first mounting platform 65 and connected to the multiple pipetting head mounting seats 61. The pitch-changing mechanism 66 is used to drive the pipetting head mounting seats 61 to move along the third direction Y, so as to adjust the distance between any two adjacent pipetting head mounting seats 61.
[0216] The shape of the first mounting platform 65 can be block-shaped, plate-shaped, column-shaped, or other irregular shapes, without limitation. The first mounting platform 65 and the fourth slide table 63 can be connected and fixed by means of adhesive, snap-fit, screw, riveting, etc.
[0217] The pipette tip mount 61 and the first mounting stage 65 can be directly or indirectly connected, without limitation. Optionally, the pipetting assembly 60 also includes a mounting back plate 651, which is connected and fixed to the first mounting stage 65 and is approximately perpendicular to the second direction X. Multiple pipette tip mounts 61 are spaced apart on the mounting back plate 651 along the third direction Y and are movable relative to the mounting back plate 651 along the third direction Y. In a specific embodiment, as shown in FIG9, there are four pipette tip mounts 61.
[0218] The variable pitch mechanism 66 can drive multiple pipette head mounting seats 61 to move along the third direction Y. For pipette heads 2003 placed at different intervals, the pipetting assembly 60 can adaptively adjust the distance between any two adjacent pipette head mounting seats 61, improve the adaptability of the pipetting assembly 60, and facilitate batch operation of pipette heads 2003 to adapt to pipetting operations of containers with different intervals and sizes.
[0219] In one embodiment, as shown in Figures 9 and 10, the pitch mechanism 66 includes a pitch driving member 661 and an adjusting plate 662. The pitch driving member 661 is disposed on the first mounting platform 65. The adjusting plate 662 is connected to the pitch driving member 661 in a transmission manner, and multiple pipette head mounting seats 61 are movably connected to the adjusting plate 662. The pitch driving member 661 is used to drive the adjusting plate 662 to move in the first direction Z, so as to drive the multiple pipette head mounting seats 61 to move in the third direction Y.
[0220] The pitch drive component 661 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation. The connection method between the pitch drive component 661 and the first mounting platform 65 can be welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0221] Optionally, the adjusting plate 662 is disposed on and slidably connected to the mounting back plate 651. A vertical rail 653 is provided on the surface of the mounting back plate 651 facing the adjusting plate 662, and the adjusting plate 662 is slidably connected to the vertical rail 653. A first horizontal rail 652 is also provided on the surface of the mounting back plate 651 facing the adjusting plate 662, and the pipette mount 61 passes through the adjusting plate 662 and is slidably connected to the first horizontal rail 652. The first horizontal rail 652 increases the movement stability of the pipette mount 61. The vertical rail 653 increases the movement stability of the adjusting plate 662.
[0222] Optionally, the adjusting plate 662 has multiple grooves (not shown) extending in different directions. The number of grooves corresponds to the number of pipette mounts 61, and each pipette mount 61 is correspondingly set with a groove. Optionally, the pipette mount 61 can move relative to the groove and along the extension direction of the groove. For example, the multiple grooves can be distributed in a fan shape, extending in a shape similar to the ribs of a fan, along the first direction Z and from the end of the adjusting plate 662 near the pipette 2003 to the end of the adjusting plate 662 away from the pipette 2003. The distance between two adjacent grooves in the third direction Y can gradually decrease or gradually increase, without limitation. Alternatively, the grooves can also extend in a roughly zigzag or arc shape. The grooves on the adjusting plate 662 can also adopt any other feasible arrangement, as long as the distance between two adjacent grooves in the third direction Y changes when the adjusting plate 662 moves along the first direction Z, without specific limitations. With this configuration, as the adjusting plate 662 moves along the first direction Z, multiple pipette mounts 61 can move along the third direction Y under the limiting and guiding effect of the slide groove, thereby changing the distance between two adjacent pipette mounts 61.
[0223] Optionally, as shown in Figures 9 and 10, the pitch mechanism 66 further includes a pitch transmission component 663. The pitch transmission component 663 is connected to the pitch drive component 661 and is connected to the pitch adjustment plate 662. The pitch transmission component 663 can drive the pitch adjustment plate 662 to move in the first direction Z under the drive of the pitch drive component 661, so as to drive the multiple pipette head mounting seats 61 to move in the third direction Y.
[0224] The variable pitch transmission component 663 can adopt any feasible transmission structure in the art, such as a gear and rack pair or a lead screw and nut pair, without limitation.
[0225] By setting the above-mentioned variable distance mechanism 66, the distance between any two adjacent pipette head mounting seats 61 can be changed, thereby changing the distance between any two adjacent pipette heads 2003. This can improve the adaptability of the pipetting assembly 60, facilitate the pipetting assembly 60 to perform batch operations on the pipette heads 2003, and meet the requirements of high-throughput experimental processing.
[0226] In one embodiment, as shown in Figures 8 to 10, the pipetting assembly 60 further includes a lower pressure plate 67, a lower pressure mechanism 68, and a plurality of separators 69. The separators 69 are disposed on the lower pressure plate 67 and are slidably connected to the lower pressure plate 67. The plurality of separators 69 correspond one-to-one with the plurality of pipetting head mounting seats 61 and can move synchronously with the pipetting head mounting seats 61 along a third direction Y. The separators 69 can also move relative to the pipetting head mounting seats 61 along a first direction Z.
[0227] Optionally, the separator 69 is disposed on the surface of the lower pressure plate 67 facing the pipette mount 61. A second horizontal track 684 is provided on the surface of the lower pressure plate 67 facing the pipette mount 61. The separator 69 is slidably connected to the second horizontal track 684 and can move relative to the lower pressure plate 67 along a third direction Y. Optionally, multiple separators 69 are connected one-to-one with multiple pipette mounts 61. For example, one end of the separator 69 away from the lower pressure plate 67 can be sleeved on the pipette mount 61 and can move relative to the pipette mount 61 along a first direction Z. With this configuration, when the pitch mechanism 66 drives the pipette mount 61 to move along a third direction Y, the separator 69 can move synchronously with the pipette mount 61 along a third direction Y, preventing the separator 69 from failing to match the pipette mount 61 when the lower pressure plate 67 drives the separator 69 to press down along the first direction Z.
[0228] Optionally, the separator 69 is generally L-shaped, comprising two ends protruding along a first direction Z and a second direction X, respectively. The end of the separator 69 protruding along the first direction Z extends toward the lower pressure plate 67 and is slidably connected to the lower pressure plate 67. The end of the separator 69 protruding along the second direction X extends toward the mounting back plate 651 and is sleeved on the end of the pipette mount 61 away from the lower pressure plate 67. Optionally, the end of the separator 69 protruding along the first direction Z is connected to the lower pressure plate 67 by a spring buffer structure 691. Exemplarily, the separator 69 includes a connecting section and a movable section, the spring buffer structure 691 is disposed between the connecting section and the movable section, and the connecting section and the movable section are movably connected by the spring buffer structure 691. The connecting section is slidably connected to the lower pressure plate 67, and the movable section is sleeved on the pipette mount 61. Optionally, the spring buffer structure 691 can be a combination of a screw and a spring, with one end of the screw movably connected to the movable section and the other end fixedly connected to the connecting section, and the spring wound around the screw with its two ends elastically abutting against the connecting section and the movable section respectively.
[0229] The pressing mechanism 68 is disposed on the first mounting platform 65 and connected to the pressing plate 67. The pressing mechanism 68 is used to drive the separating member 69 to move along the first direction Z to separate the pipette head 2003 and the pipette head mounting base 61.
[0230] The pressing mechanism 68 includes a pressing drive component 681 and a pressing transmission component 682. Optionally, the pressing drive component 681 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., and the pressing transmission component 682 can adopt any feasible transmission structure in the art without limitation. Optionally, the pressing drive component 681 can be a linear motor, and the pressing transmission component 682 includes a lead screw and nut pair. The lead screw is connected to the drive shaft of the pressing drive component 681 through a coupling and extends along the first direction Z. The nut is connected to the pressing plate 67. The pressing drive component 681 drives the lead screw to rotate, causing the nut to move linearly on the lead screw, thereby driving the pressing plate 67 to move along the first direction Z, so as to drive the separating component 69 to move along the first direction Z.
[0231] When the pressure plate 67 is driven down by the pressure mechanism 68, the separator 69 moves down along the first direction Z under the action of the pressure plate 67 and presses against the pipette head 2003 installed at the end of the pipette head mounting base 61, thereby causing the pipette head 2003 to fall off. When the pipette head 2003 needs to be installed on the pipette head mounting base 61, the pipette head mounting base 61 moves down under the action of the third lifting mechanism 64 of the pipetting assembly 60, and the pipette head 2003 moves up relative to the pipette head mounting base 61 and presses against the separator 69 at the end of the pipette head mounting base 61. Since the spring buffer structure 691 can deform and provide movable space for the separator 69 along the first direction Z, the separator 69 moves up under the action of the spring buffer structure 691 until the installation of the pipette head 2003 is completed.
[0232] Optionally, the pipetting assembly 60 is also provided with a pipetting tip recovery box for recovering pipetting tips 2003 removed from the pipetting tip mount 61.
[0233] Optionally, as shown in Figure 10, the pipetting assembly 60 is further provided with a sensing element 683, which can be disposed on the separating member 69. When the separating member 69 moves along the first direction Z and towards the lower pressure plate 67 by a distance within a preset range under the pressure of the pipetting head 2003, the sensing element 683 receives a signal indicating that the pipetting head 2003 is installed in place. For example, the sensing element 683 includes a sensor and a sensing plate. The sensor is disposed on the connecting section of the separating member 69, and the sensing plate is disposed on the movable section of the separating member 69. The sensor can be a photoelectric sensor. When the sensing plate is inserted into the sensor, it indicates that the pipetting head 2003 is installed in place, at which point the downward movement of the pipetting head mounting base 61 can be stopped. This configuration prevents insufficient downward movement of the pipetting head mounting base 61, which could lead to insecure installation and poor sealing of the pipetting head 2003, and also prevents excessive downward movement of the pipetting head mounting base 61, which could damage the pipetting head 2003.
[0234] By setting up the above-mentioned pipetting assembly 60, the used pipetting head 2003 can be separated from the pipetting head mounting base 61, and new pipetting heads 2003 can also be installed, thus facilitating the replacement of the pipetting head 2003 on the pipetting head mounting base 61. The structure is simple. The separator 69 can also adjust its position according to the distance between two adjacent pipetting head mounting bases 61, which has a high degree of adaptability and facilitates batch operation.
[0235] In one embodiment, as shown in Figures 6 to 8, 11, and 12, the sampling device 300 further includes a second clamping assembly 70, which is connected to a fourth slide 63 and is used to clamp and move a test tube 2004, which is used to hold sample liquid or diluent. The second clamping assembly 70 is disposed on the fourth slide 63, allowing the third lifting mechanism 64 to drive the second clamping assembly 70 and the pipette head mounting base 61 to move synchronously along the first direction Z, simplifying the driving method and increasing the device's integration.
[0236] The second clamping assembly 70 includes a second mounting platform 71, a fourth lifting mechanism 72, and a second tube clamping mechanism 73. The second mounting platform 71 is connected and fixed to the fourth slide table 63. The fourth lifting mechanism 72 is disposed on the second mounting platform 71 and connected to the second tube clamping mechanism 73. The fourth lifting mechanism 72 is used to drive the second tube clamping mechanism 73 to move relative to the second mounting platform 71 along the first direction Z. The second tube clamping mechanism 73 is used to clamp the test tube 2004.
[0237] The shape of the second mounting platform 71 can be block-shaped, plate-shaped, column-shaped, or other irregular shapes, without limitation. Optionally, the second mounting platform 71 and the fourth slide 63 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, or other methods, without limitation.
[0238] The fourth lifting mechanism 72 can be any feasible drive transmission structure in the art. Optionally, the fourth lifting mechanism 72 includes a fourth lifting drive member 721 and a fourth transmission rod (not shown). The fourth lifting drive member 721 is disposed on the second mounting platform 71, and the fourth transmission rod extends along the first direction Z and is drively connected to the fourth lifting drive member 721.
[0239] Optionally, the fourth transmission rod is connected to the second clamping mechanism 73. The connection method can be direct or indirect, without limitation. The fourth lifting drive 721 can be used to drive the fourth transmission rod to move along its own axial direction. The fourth lifting drive 721 has a drive shaft. When the fourth lifting drive 721 is running, the drive shaft can move linearly to drive the second clamping mechanism 73 to move along the first direction Z.
[0240] Optionally, the fourth transmission rod rotates around its own axis under the drive of the fourth lifting drive 721 and is connected to the second clamping mechanism 73 through a nut. The fourth transmission rod and the nut form a screw-nut pair, which can convert the rotational motion of the fourth transmission rod into the linear motion of the second clamping mechanism 73. The second clamping mechanism 73 can move along the axial direction (i.e., the first direction Z) of the fourth transmission rod under the transmission connection of the fourth transmission rod.
[0241] The second clamping assembly 70 can transport the test tube 2004 to a designated position that facilitates liquid aspiration by the pipetting assembly 60, replacing manual handling and meeting the needs of automated experiments. The fourth lifting mechanism 72 can drive the second clamping mechanism 73 to move along the first direction Z, or the third lifting mechanism 64 can drive the second clamping assembly 70 to move along the first direction Z, thereby realizing the transfer of the test tube 2004. In addition, the fourth lifting mechanism 72 driving the second clamping mechanism 73 to move relative to the pipetting assembly 60 along the first direction Z can avoid interference between the second clamping mechanism 73 and the pipetting assembly 60.
[0242] Test tube 2004 can be used to store small amounts of chemical or biological samples. Test tube 2004 can be selected from glass test tubes 2004, plastic test tubes 2004, etc., as needed, without limitation. The experimental platform 1000 in this embodiment can be operated using any feasible test tube 2004 in the art, without limitation.
[0243] Optionally, the test tube 2004 includes a tube body and a cap. The tube body is used to hold the sample liquid or diluent, and the cap is used to seal the tube body to prevent the liquid in the test tube 2004 from being contaminated by impurities in the external environment, thus ensuring the purity of the liquid.
[0244] In one embodiment, as shown in Figures 8, 11, and 12, the second clamping mechanism 73 includes a second clamping drive 731, a third clamping portion 732, and a fourth clamping portion 733. The second clamping drive 731 is connected to the fourth lifting mechanism 72. At least one of the third clamping portion 732 and the fourth clamping portion 733 is connected to the second clamping drive 731. The second clamping drive 731 is used to cause the third clamping portion 732 and the fourth clamping portion 733 to move relative to each other to clamp the test tube 2004.
[0245] Optionally, as shown in Figure 11, the second clamping mechanism 73 further includes a first fixing plate 734 and a second fixing plate 735. The first fixing plate 734 can be connected to the fourth lifting mechanism 72. The first fixing plate 734 and the second fixing plate 735 are opposite to each other and spaced apart in the first direction Z, and are connected and fixed together by a connector. The first fixing plate 734 is closer to the second mounting platform 71 than the second fixing plate 735. The second clamping drive member 731 is connected to the first fixing plate 734 and / or the second fixing plate 735. The connection method can be adhesive, snap-fit, screw, riveting, etc., without limitation. Optionally, at least one of the third clamping part 732 and the fourth clamping part 733 is slidably connected to the second fixing plate 735. To improve space utilization, the second clamping drive member 731 can be disposed between the first fixing plate 734 and the second fixing plate 735.
[0246] The third clamping part 732 can be a one-piece structure manufactured using a molding process, or it can be a separate structure. The various parts of the third clamping part 732 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation. Similarly, the structure of the fourth clamping part 733 can be referred to the aforementioned third clamping part 732, and will not be described again.
[0247] Optionally, at least one of the third clamping part 732 and the fourth clamping part 733 is connected to the second clamping drive member 731 and can slide relative to the second fixed plate 735 under the drive of the second clamping drive member 731 to generate relative movement. When the third clamping part 732 and the fourth clamping part 733 move relative to each other, they can be used to clamp a single test tube 2004 or multiple test tubes 2004, without limitation.
[0248] Optionally, when the third clamping part 732 and the fourth clamping part 733 move towards each other, the second clamping mechanism 73 clamps the test tube 2004; when the third clamping part 732 and the fourth clamping part 733 move away from each other, the second clamping mechanism 73 releases the test tube 2004. Alternatively, when the third clamping part 732 and the fourth clamping part 733 move away from each other, the second clamping mechanism 73 clamps the test tube 2004; when the third clamping part 732 and the fourth clamping part 733 move towards each other, the second clamping mechanism 73 releases the test tube 2004. There are no restrictions.
[0249] By setting the second clamping mechanism 73, the test tube 2004 can be clamped and moved to a designated position, which is simple to operate.
[0250] In one embodiment, as shown in Figures 11 and 12, the third clamping part 732 includes a third mounting plate 7321 and multiple sets of third fingers 7322, which are spaced apart on the third mounting plate 7321, and each set of third fingers 7322 includes at least one third finger 7322; the fourth clamping part 733 includes a fourth mounting plate 7331 and multiple sets of fourth fingers 7332, which are spaced apart on the fourth mounting plate 7331, and each set of fourth fingers 7332 includes at least one fourth finger 7332; the multiple sets of third fingers 7322 and the multiple sets of fourth fingers 7332 correspond one-to-one, and the third fingers 7322 and the fourth fingers 7332 are used to move relative to each other to clamp the test tube 2004.
[0251] Optionally, the third clamping part 732 and the fourth clamping part 733 move relative to each other along the third direction Y.
[0252] At least one of the third mounting plate 7321 and the fourth mounting plate 7331 is connected to the second clamping drive member 731. Optionally, the third mounting plate 7321 and the fourth mounting plate 7331 are disposed on opposite sides of the second clamping drive member 731 in the third direction Y, and are generally symmetrically arranged, with the axis of symmetry extending along the first direction Z. Optionally, both the third mounting plate 7321 and the fourth mounting plate 7331 are generally Z-shaped. The third mounting plate 7321 includes a fifth sub-plate, a sixth sub-plate, and a seventh sub-plate connected in sequence, and the fifth and seventh sub-plates are generally parallel to the first direction Z, while the sixth sub-plate is generally perpendicular to the first direction Z (parallel to the third direction Y). Optionally, the fifth sub-plate is opposite to the second clamping drive member 731 in the third direction Y, the sixth sub-plate is slidably connected to the second fixed plate 735 through the slider 736, the seventh sub-plate is connected to the finger mounting member 737, and multiple sets of third fingers 7322 are spaced apart on the finger mounting member 737. The finger mounting member 737 can be a plate, column, block, etc., without limitation.
[0253] The structure of the fourth mounting plate 7331 is the same as that of the third mounting plate 7321, and will not be described again.
[0254] Optionally, the third finger 7322 is generally cylindrical in shape and extends along the first direction Z to increase the contact area between the third finger 7322 and the test tube 2004, thereby increasing the clamping stability. Multiple third fingers 7322 in each group are spaced apart, and the spacing between multiple groups of third fingers 7322 is approximately the same. Optionally, multiple third fingers 7322 in each group are connected into a single unit via a connecting platform. In one specific embodiment, there are four groups of third fingers 7322, spaced apart along the third direction Y. Each group of third fingers 7322 includes two third fingers 7322, which are spaced apart along the second direction X. It is understood that the shape of the third finger 7322 can also be V-shaped, arc-shaped, etc., without limitation.
[0255] Similarly, the setup for the fourth finger 7332 is similar to that for the third finger 7322, so you can refer to it and I won't go into details again.
[0256] In one specific embodiment, when the third finger 7322 and the fourth finger 7332 move towards each other, the second clamping mechanism 73 clamps the test tube 2004; when the third finger 7322 and the fourth finger 7332 move away from each other, the second clamping mechanism 73 releases the test tube 2004. During operation, the second clamping mechanism 73 moves along the first direction Z under the drive of the fourth lifting mechanism 72, positioning the third finger 7322 and the fourth finger 7332 on both sides of the test tube 2004. Then, the second clamping drive member 731 causes the third clamping part 732 and the fourth clamping part 733 to move relative to each other, reducing the distance between the third finger 7322 and the fourth finger 7332 until both the third finger 7322 and the fourth finger 7332 are in contact with the wall of the test tube 2004, completing the clamping action of the second clamping mechanism 73. Subsequently, the second translation mechanism 301 drives the third slide 302 to move along the second direction X, which in turn drives the second clamping mechanism 73 to move along the second direction X until the test tube 2004 held between the third finger 7322 and the fourth finger 7332 moves to the designated position. At this time, the second clamping mechanism 73 can be lowered by the fourth lifting mechanism 72 to place the test tube 2004 at the designated position. After placement, the second clamping drive 731 causes the third clamping part 732 and the fourth clamping part 733 to move relative to each other, and the third finger 7322 and the fourth finger 7332 move away from each other to release the test tube 2004, completing the movement and placement of the test tube 2004.
[0257] By setting the second clamping mechanism 73, multiple test tubes 2004 can be clamped and moved simultaneously, resulting in high experimental efficiency. Furthermore, the multiple sets of third fingers 7322 and multiple sets of fourth fingers 7332 move the same distance, eliminating errors in the moving distance and improving the accuracy of batch operations.
[0258] In one embodiment, as shown in Figures 11 and 12, the third clamping part 732 further includes a mounting shaft 7323, a limiting ring 7324, and a preload spring 7325. The mounting shaft 7323 is connected to the third mounting plate 7321 and extends along the moving direction of the third clamping part 732. Each group of third fingers 7322 is slidably connected to the mounting shaft 7323. A limiting ring 7324 is provided on the side of each group of third fingers 7322 away from the corresponding fourth finger 7332. The limiting ring 7324 is sleeved on the mounting shaft 7323 and connected and fixed to the mounting shaft 7323. A preload spring 7325 is provided between each group of third fingers 7322 and the corresponding limiting ring 7324. One end of the preload spring 7325 is connected and fixed to the limiting ring 7324, and the other end is used to elastically abut against the third finger 7322.
[0259] Optionally, the mounting shaft 7323 extends in the third direction Y, and one end of the mounting shaft 7323 is connected and fixed to the seventh sub-plate. Optionally, there are multiple limiting rings 7324 and preload springs 7325, and the number is the same as the number of groups of third fingers 7322, that is, each group of third fingers 7322 corresponds to one limiting ring 7324 and one preload spring 7325. Optionally, there are multiple limiting rings 7324 and preload springs 7325, and the number is the same as the number of third fingers 7322, that is, each third finger 7322 corresponds to one limiting ring 7324 and one preload spring 7325. For example, when the third clamping part 732 is provided with four sets of third fingers 7322, and each set of third fingers 7322 includes two third fingers 7322, there are eight limiting rings 7324 and eight pre-tension springs 7325, and two mounting shafts 7323 are provided at intervals in the second direction X. Each mounting shaft 7323 is connected to four limiting rings 7324 and four pre-tension springs 7325.
[0260] The preload spring 7325 can be any spring feasible in the art, such as compression springs, tension springs, etc., without limitation. Optionally, the preload spring 7325 can be connected and fixed to the limiting ring 7324 and the third finger 7322, or it can be elastically abutted, without limitation.
[0261] When the third clamping part 732 and the fourth clamping part 733 move relative to each other, the third finger 7322 and the fourth finger 7332 move closer to each other, and at this time the third finger 7322 and the fourth finger 7332 can contact the side wall of the test tube 2004; the third clamping part 732 and the fourth clamping part 733 continue to move relative to each other, and at this time the distance between the third finger 7322 and the fourth finger 7332 further decreases. The end of the pre-tensioning spring 7325 away from the limiting ring 7324 will elastically abut against the third finger 7322 and generate a pre-tensioning force on the third finger 7322. The third finger 7322 and the fourth finger 7332 can work together to clamp the test tube 2004, which can prevent the test tube 2004 from falling in the middle and prevent the test tube 2004 from being damaged due to excessive force.
[0262] By setting the third clamping part 732, when the third clamping part 732 and the fourth clamping part 733 move relative to each other to clamp the test tube 2004, the pre-tensioning spring 7325 can generate a pre-tensioning force on the third finger 7322, thereby improving the clamping stability and safety of the second clamping mechanism 73.
[0263] It is understood that the structure of the fourth clamping part 733 can be the same as or similar to the structure of the third clamping part 732, or it can be different, without limitation. For example, in addition to including the aforementioned fourth mounting plate 7331 and multiple sets of fourth fingers 7332, the fourth clamping part 733 may also include a finger mounting member 737. The finger mounting member 737 is connected and fixed to the fourth mounting plate 7331, and multiple sets of fourth fingers 7332 are fixedly connected to it at equal intervals. The finger mounting member 737 can be plate-shaped, strip-shaped, etc., without limitation.
[0264] In one embodiment, as shown in FIG12, the second clamping mechanism 73 further includes a third transmission member 738 and a fourth transmission member 739. The second clamping drive member 731 is connected to the third transmission member 738 and the fourth transmission member 739 respectively. The third transmission member 738 is connected to the third clamping part 732, and the fourth transmission member 739 is connected to the fourth clamping part 733. The second clamping drive member 731 is used to drive the third transmission member 738 and the fourth transmission member 739 to move in opposite directions.
[0265] The third transmission component 738 and the third clamping part 732 can be connected and fixed by means of welding, bonding, snap-fitting, screwing, riveting, etc., without limitation. Optionally, the third transmission component 738 is connected to the surface of the third mounting plate 7321 facing away from the third finger 7322. Optionally, the second clamping drive component 731 drives the third transmission component 738 to move or rotate, thereby driving the third clamping part 732 to move. The connection method between the fourth transmission component 739 and the fourth clamping part 733 can refer to that between the third transmission component 738 and the third clamping part 732, and there is no specific limitation.
[0266] Optionally, at least one of the third transmission member 738 and the fourth transmission member 739 may be a single rack, a rack group formed by the meshing of multiple racks, or a rack with other transmission structures (such as gears), without specific limitations. In a specific embodiment, the second clamping drive member 731 is a motor, and the second clamping mechanism 73 further includes a gear. The transmission gear is connected to the second clamping drive member 731 and rotates under the drive of the second clamping drive member 731. The third transmission member 738 and the fourth transmission member 739 are both racks and mesh with the gears respectively. When the second clamping drive member 731 drives the gears to rotate, the third transmission member 738 and the fourth transmission member 739 respectively drive the third clamping part 732 and the fourth clamping part 733 to move in opposite directions to clamp or release the test tube 2004.
[0267] In another embodiment, as shown in Figure 12, the second clamping drive 731 is a linear motor, and both the third transmission 738 and the fourth transmission 739 include a lead screw and nut pair. Specifically, the lead screws of the third transmission 738 and the fourth transmission 739 are connected to the drive shaft of the second clamping drive 731. The nut of the third transmission 738 is connected to the third clamping part 732, and the nut of the fourth transmission 739 is connected to the fourth clamping part 733. When the drive shaft of the second clamping drive 731 rotates, the lead screws of the third and fourth drives rotate in opposite directions, or the nuts of the third and fourth drives move in opposite directions along the lead screws, thereby driving the third clamping part 732 and the fourth clamping part 733 to move relative to each other to clamp or release the test tube 2004.
[0268] The second clamping mechanism 73 also includes a third transmission component 738 and a fourth transmission component 739. The second clamping drive component 731 is used to drive the third transmission component 738 and the fourth transmission component 739 to move in opposite directions, and to drive the third clamping part 732 and the fourth clamping part 733 to move relative to each other. The transmission method is simple and reliable.
[0269] In one embodiment, as shown in Figures 7 and 13, the sampling device 300 further includes a pipette tray assembly 80. The pipette tray assembly 80 includes a pipette tray placement seat 81 and a second moving mechanism. The pipette tray placement seat 81 is slidably connected to the base 200 and is movable along a second direction X and / or a third direction Y. The second moving mechanism is disposed on the base 200 and connected to the pipette tray placement seat 81. The second moving mechanism is used to drive the pipette tray placement seat 81 to move relative to the base 200. The pipette tray placement seat 81 is used to hold pipettes 2003.
[0270] The pipette tray holder 81 is used to hold a pipette tray, which contains multiple pipette tips 2003, facilitating batch operations on multiple pipette tips 2003. The pipette tray holder 81 can be roughly rectangular, square, trapezoidal, etc., and the shape of the pipette tray holder 81 can correspond to the shape of the pipette tray, without specific restrictions.
[0271] Optionally, the pipette tray holder 81 is used to hold a single pipette tray, and multiple pipette tips 2003 can be arranged in a multi-row, multi-column array within the pipette tray. Alternatively, the pipette tray holder 81 is used to hold multiple pipette trays, with at least one pipette tip 2003 placed on each pipette tray, without limitation.
[0272] Optionally, the second moving mechanism can be directly mounted on the base 200; or, as shown in Figure 13, the pipette tray assembly 80 further includes a fixing seat 83, which is mounted on the base 200, and the second moving mechanism is mounted on the fixing seat 83 and connected to the pipette tray placement seat 81.
[0273] The second moving mechanism can be any feasible drive transmission structure in the art. Optionally, the second moving mechanism includes a second moving drive component 821, which is disposed on the fixed base 83. The second moving drive component 821 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation.
[0274] Optionally, the pipette tray holder 81 can move relative to the fixed seat 83 along a third direction Y. The second moving drive 821 can be a linear motor, and the second moving mechanism also includes a fourth transmission part 822. The fourth transmission part 822 includes a lead screw and nut pair, the lead screw is connected to the drive shaft of the second moving drive 821 via a coupling, and the nut is connected to the pipette tray holder 81. Optionally, the lead screw of the second transmission part 822 extends along a third direction Y. The second moving drive 821 drives the lead screw to rotate, causing the nut to move linearly on the lead screw, thereby driving the pipette tray holder 81 to move along a third direction Y on the fixed seat 83.
[0275] Optionally, when the pipetting assembly 60 needs to be fitted with a pipetting tip 2003, the pipetting tip tray holder 81 can be moved along a third direction Y to below the pipetting assembly 60, that is, in the orthographic projection along the first direction Z, at least a portion of the pipetting tip tray holder 81 coincides with the pipetting assembly 60, so as to facilitate the installation of the pipetting tip 2003 on the pipetting tip mounting holder 61.
[0276] By setting up the pipette tray assembly 80, the entire tray of pipette heads 2003 can be loaded and unloaded, which facilitates batch experimental operations of the pipette assembly 60, improves experimental efficiency, and meets the requirements of high-throughput experimental processing.
[0277] In one embodiment, as shown in FIG13, the pipette tray assembly 80 further includes a pipette mounting bracket 84, which is connected to a second moving mechanism. A pipette tray placement seat 81 is disposed on the pipette mounting bracket 84. A clearance space 841 is provided between the pipette mounting bracket 84 and the base 200. The clearance space 841 is capable of accommodating at least a portion of the flash filter bottle tray placement seat 51.
[0278] The pipette tray holder 81 and the pipette mounting bracket 84 can be an integral structure; or, the pipette tray holder 81 and the pipette mounting bracket 84 can also be separate structures. The pipette tray holder 81 and the pipette mounting bracket 84 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0279] Optionally, the pipette mount 84 is generally U-shaped, comprising a first sub-part and a second sub-part that are opposite to and spaced apart in the first direction Z, and a third sub-part connecting the first and second sub-parts. The first sub-part is slidably connected to the mounting base, and the surface of the second sub-part facing away from the first sub-part is used to place the pipette tray holder 81. The first, second, and third sub-parts directly enclose to form a clearance space 841. Optionally, the pipette mount 84 is generally L-shaped, and the combination of the pipette mount 84 and the pipette tray holder 81 can generally form a U-shape.
[0280] Optionally, referring to the aforementioned configuration of the flash filtration flask tray holder 51, when both the flash filtration flask tray holder 51 and the pipette tip tray holder 81 are located at the pipetting station, as shown in Figures 6 and 7, the first tray holder 511 and the pipette tip tray holder 81 are approximately on the same straight line in the second direction X, facilitating the movement of the pipetting assembly 60 between the first tray holder 511 and the pipette tip tray. In this case, in the orthographic projection in the first direction Z, at least a portion of the second tray holder 512 overlaps with the pipette tip tray holder 81, meaning at least a portion of the second tray holder 512 is accommodated in the clearance space 841. For example, the first tray holder 511 is used to hold the outer tube tray of the flash filtration flask, and the second tray holder 512 is used to hold the inner tube tray of the flash filtration flask, and both the second tray holder 512 and the inner tube tray of the flash filtration flask can be accommodated in the clearance space 841.
[0281] With this setup, there is no need to provide additional clearance space for the second tray placement seat 512 on the moving path of the flash filter tray placement seat 51 along the third direction Y. This can reduce the overall volume of the experimental platform 1000, improve space utilization, avoid interference between different components, and make the flow path between different workstations reasonable.
[0282] In one embodiment, as shown in Figures 6 and 14, the sampling device 300 further includes a test tube holder assembly 90, which includes a test tube holder placement seat 91 and a test tube mounting rack 92. The test tube mounting rack 92 is mounted on the base 200, and the test tube holder placement seat 91 is disposed on the test tube mounting rack 92. The test tube holder placement seat 91 is used to hold test tubes 2004.
[0283] The test tube mounting rack 92 and the base 200 can be an integral structure; or, the test tube mounting rack 92 and the base 200 can also be a separate structure. The test tube mounting rack 92 and the base 200 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without any restrictions.
[0284] The test tube holder 91 is used to hold a test tube holder containing multiple test tubes 2004, facilitating batch processing of multiple test tubes 2004. The test tube holder 91 can be roughly rectangular, square, trapezoidal, etc., as long as the shape of the test tube holder 91 corresponds to the shape of the test tube holder, without specific restrictions.
[0285] Optionally, the test tube holder 91 is used to hold a single test tube holder, and multiple test tubes 2004 can be arranged in a multi-row, multi-column array within the test tube holder. Alternatively, the test tube holder 91 is used to hold multiple test tube holders, with each test tube holder containing at least one test tube 2004, without limitation.
[0286] The test tube mounting rack 92 is spaced apart from the flash filter device 100 in the third direction Y and from the pipette tray assembly 80 in the second direction X.
[0287] Optionally, the test tube holder 91 can be fixedly connected to the test tube mounting rack 92, or it can be movably connected to the test tube mounting rack 92, without limitation. In a specific embodiment, the test tube holder assembly 90 further includes a third moving mechanism (not shown), which is disposed on the test tube mounting rack 92 and connected to the test tube holder 91. The third moving mechanism can drive the test tube holder 91 to slide relative to the test tube mounting rack 92 along the second direction X and / or the third direction Y. For example, when the test tube holder 91 moves relative to the test tube mounting rack 92 along the second direction X, the test tube holder 91 can extend from the base 200, facilitating the loading and unloading of test tubes 2004. When the test tube holder 91 moves relative to the test tube mounting bracket 92 in the third direction Y, the position of the next set of test tubes 2004 is adjusted in a timely manner after the second clamping component 70 has transferred a set of test tubes 2004, so that the second clamping component 70 can clamp them; or the position of the next set of test tubes 2004 is adjusted in a timely manner after the pipetting component 60 has aspirated a set of test tubes 2004, so that the pipetting component 60 can perform the next pipetting operation, which is highly flexible.
[0288] The third moving mechanism can adopt any feasible transmission structure in the field, without limitation. Optionally, the configuration of the third moving mechanism can refer to the aforementioned second moving mechanism, and will not be repeated here.
[0289] By setting up the test tube rack assembly 90 and the test tube rack placement seat 91 for holding test tubes 2004, the loading and unloading of the entire rack of test tubes 2004 can be carried out, which facilitates the batch experimental operation of the sampling device 300, improves experimental efficiency, and meets the requirements of high-throughput experimental processing.
[0290] In one embodiment, as shown in Figures 7 and 15, the sampling device 300 further includes a third clamping component 93, which is positioned close to the test tube holder assembly 90 to facilitate the reduction of the transfer time of the test tube 2004. The third clamping component 93 is used to open and close the caps of the test tube 2004.
[0291] The third clamping assembly 93 includes a third clamping mechanism 931, which clamps the body of the test tube 2004 and rotates it about a first axis L1. The third clamping mechanism 931 can cooperate with the second clamping mechanism 73 to open or close the test tube 2004. The first axis L1 coincides with the axis of the test tube 2004. Optionally, the first axis L1 extends along a first direction Z.
[0292] Optionally, the third clamping assembly 93 further includes a gripper bracket 94, which is mounted on the base 200 and located between the test tube holder assembly 90 and the pipette tip tray assembly 80. The third tube clamping mechanism 931 is disposed on the gripper bracket 94. The gripper bracket 94 and the base 200 can be an integral structure, or they can be separate structures. The gripper bracket 94 and the base 200 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation. Optionally, the gripper bracket 94 and the test tube mounting bracket 92 can also be an integral structure.
[0293] Optionally, the third clamping mechanism 931 is approximately symmetrical about the center of the first axis L1. With this configuration, the weight distribution of the third clamping mechanism 931 is more uniform, and its center of gravity is less likely to shift during rotation around its own first axis L1, resulting in a longer service life. The clamping of the test tube 2004 by the third clamping mechanism 931 is also more stable, and the tube body of the test tube 2004 is less likely to tilt.
[0294] The test tube 2004 contained in the test tube holder assembly 90 is in a closed state, meaning the tube body and cap of the test tube 2004 are locked together, preventing the sample liquid in the test tube 2004 from being contaminated by the external environment. Therefore, before the pipette tip 2003 draws sample liquid from the test tube 2004, the cap of the test tube 2004 needs to be opened manually or mechanically to facilitate the pipetting operation of the pipette tip 2003. The third clamping assembly 93 is located at the cap opening position. The second clamping mechanism 73 of the second clamping assembly 70 clamps the cap of the test tube 2004 from the test tube holder assembly 90 and moves it above the third clamping mechanism 931. The third clamping mechanism 931 clamps the body of the test tube 2004 and cooperates with the second clamping mechanism 73. The second clamping mechanism 73 clamps the cap of the test tube 2004 and keeps it stationary, while the third clamping mechanism 931 clamps the body of the test tube 2004 and rotates it around its own axis. Relative rotation occurs between the body and cap of the test tube 2004, causing the cap to detach from the body, facilitating the pipette tip 2003 to insert into the test tube 2004 to draw the sample liquid. After the pipette tip 2003 has drawn the liquid, the second clamping mechanism 73 and the third clamping mechanism 931 can tighten the body and cap of the test tube 2004 in a similar manner to prevent the sample liquid in the test tube 2004 from spilling and contaminating the experimental platform 1000. It is understandable that the third clamping mechanism 931 can clamp the body of the test tube 2004 and keep it stationary, while the second clamping mechanism 73 can clamp the cap of the test tube 2004 and rotate it; this is not limited here.
[0295] In one embodiment, as shown in Figures 15 and 16, the third clamping mechanism 931 includes a third clamping drive 9311, a finger mounting base 9312, and a plurality of fifth fingers 9313. The third clamping drive 9311 is disposed on the finger mounting base 9312, and the plurality of fifth fingers 9313 are spaced apart circumferentially along the finger mounting base 9312. The third clamping drive 9311 is connected to the fifth fingers 9313 and is used to drive the fifth fingers 9313 to move radially along the finger mounting base 9312 to clamp the tube body of the test tube 2004.
[0296] The third clamping drive component 9311 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation. Optionally, the third clamping drive component 9311 is located at the end of the finger mounting base 9312 facing away from the fifth finger 9313. The connection method between the third clamping drive component 9311 and the finger mounting base 9312 can be welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0297] Optionally, an electric slip ring 9314 is provided at the end of the third clamping drive 9311 away from the finger mounting base 9312. The electric slip ring 9314 is used to transmit electrical energy to the third clamping drive 9311.
[0298] Optionally, in the orthographic projection of the first direction Z, the shape of the finger mounting base 9312 can be approximately circular, a regular polygon, etc., without limitation. The shape of the fifth finger 9313 can be strip-shaped, sheet-shaped, column-shaped, block-shaped, claw-shaped, etc., without limitation. The number of fifth fingers 9313 is not limited, specifically it can be three, four, five, etc. Optionally, multiple fifth fingers 9313 are slidably connected to the finger mounting base 9312 and are arranged approximately centrally symmetrically along the first axis L1.
[0299] Optionally, the third clamping drive 9311 can be connected to the fifth finger 9313 via any feasible transmission structure in the art. The second clamping mechanism 73 clamps the cap of the test tube 2004 and moves the test tube 2004 above the third clamping mechanism 931, with at least a portion of the tube body of the test tube 2004 extending between the plurality of fifth fingers 9313 of the third clamping mechanism 931. At this time, the plurality of fifth fingers 9313 move radially toward the test tube 2004 along the finger mounting seat 9312 and abut against the outer wall of the test tube 2004 to clamp the tube body of the test tube 2004. When removing the test tube 2004, the plurality of fifth fingers 9313 first move radially away from the test tube 2004 under the drive of the third clamping drive 9311, and the second clamping mechanism 73 clamps the cap of the test tube 2004 and moves the test tube 2004 upward to remove the test tube 2004.
[0300] By setting the aforementioned third clamping mechanism 931, the transmission method is simple and efficient.
[0301] In one embodiment, as shown in Figures 15 and 16, there are multiple third clamping mechanisms 931. The third clamping assembly 93 further includes a rotary drive 932, a first gear 933, and a second gear 934. The rotary drive 932 is connected to the first gear 933. Each third clamping mechanism 931 is connected to a second gear 934, and the second gear 934 is coaxially arranged with the third clamping mechanism 931. The first gear 933 meshes with one of the second gears 934, and two adjacent second gears 934 mesh. The rotary drive 932 is used to drive the first gear 933 to rotate, and then drive the multiple third clamping mechanisms 931 to rotate synchronously around the first axis L1 through the second gear 934.
[0302] The number of third clamping mechanisms 931 is the same as the number of sets of fourth fingers 7332 (or third fingers 7322) in the second clamping mechanism 73. The arrangement direction of the multiple third clamping mechanisms 931 is the same as the arrangement direction of the multiple sets of fourth fingers 7332, and the distance between two adjacent third clamping mechanisms 931 is the same as the distance between two adjacent sets of fourth fingers 7332. For example, multiple sets of fourth fingers 7332 are spaced apart along a third direction Y, and multiple third clamping mechanisms 931 are spaced apart along a third direction Y on the gripper bracket 94, and the distance between two adjacent third clamping mechanisms 931 is the same as the distance between two adjacent sets of fourth fingers 7332, which facilitates batch operation.
[0303] Optionally, the rotary drive component 932 is disposed on the gripper bracket 94. The rotary drive component 932 can be a motor, hydraulic cylinder, pneumatic cylinder, etc., without limitation. Optionally, the rotary drive component 932 is a motor, and the drive shaft of the rotary drive component 932 is connected to the first gear 933 and can drive the first gear 933 to rotate.
[0304] Optionally, the second gear 934 is fitted onto the finger mounting seat 9312 of the third clamping mechanism 931. Optionally, the second gear 934 fitted onto the outermost of the plurality of third clamping mechanisms 931 meshes with the first gear 933, which can transmit the power of the rotary drive 932 to the third clamping mechanism 931.
[0305] Optionally, the third clamping assembly 93 also includes a third gear 935, which meshes with two adjacent second gears 934. That is, all the second gears 934 connected to the third clamping mechanism 931 mesh directly or indirectly with the first gear 933. All the third clamping mechanisms 931 can be driven to rotate simultaneously by a rotary drive 932, making the transmission method simple and efficient.
[0306] Optionally, the modules of the first gear 933, the second gear 934, and the third gear 935 can be the same or different, without restriction.
[0307] The rotary drive 932 and the third clamping mechanism 931 can also be connected by any other feasible transmission structure, without any specific restrictions.
[0308] By setting the third clamping component 93, the opening and closing operations of batch test tubes 2004 can be performed. The transmission method is simple and efficient, and the experimental throughput is high.
[0309] In one embodiment, as shown in FIG14, a magnet mounting plate 921 is provided on the side of the test tube mounting rack 92 near the third clamping assembly 93. The magnet mounting plate 921 extends toward the arrangement direction of the plurality of third tube clamping mechanisms 931. A plurality of magnets 922 are provided on the magnet mounting plate 921 at intervals, and the plurality of magnets 922 correspond one-to-one with the plurality of third tube clamping mechanisms 931.
[0310] Optionally, the magnet mounting plate 921 and the test tube mounting rack 92 can be an integrated structure or a separate structure. The magnet mounting plate 921 and the test tube mounting rack 92 can be connected and fixed by welding, bonding, snap-fitting, screwing, riveting, etc., without limitation.
[0311] Optionally, magnet 922 is disposed on the surface of magnet mounting plate 921 facing away from test tube holder 91 to avoid interference with test tubes 2004 in test tube holder. Magnet 922 can be connected and fixed to magnet mounting plate 921 by means of adhesive, snap-fit, etc., without limitation.
[0312] Magnet 922 is used to attract the magnetic particles inside test tube 2004. Optionally, test tube 2004 in test tube holder 91 needs to be magnetically stirred in the previous step before entering experimental platform 1000, therefore, magnetic particles are placed inside test tube 2004. To prevent the magnetic particles from affecting the pipette 2003's insertion into test tube 2004 and aspiration of sample liquid (or other liquid), the magnetic particles can be attracted to one side of test tube 2004 by magnet 922 on magnet mounting plate 921. In addition, when test tube 2004 needs to be opened before aspirating sample liquid, the magnetic particles inside test tube 2004 are attracted to one side of magnet mounting plate 921 by magnet 922 and remain stationary, while the tube body of test tube 2004 drives the sample liquid inside to rotate, and the magnetic particles can act as a stirrer for the sample, further mixing the sample liquid.
[0313] In one embodiment, as shown in FIG8, the second clamping assembly 70 further includes a buffer mechanism 74 and a third mounting platform 75. The third mounting platform 75 is connected to the fourth lifting mechanism 72. The buffer mechanism 74 is disposed between the third mounting platform 75 and the second clamping mechanism 73 and is used to move the second clamping mechanism 73 relative to the third mounting platform 75 in the first direction Z.
[0314] Optionally, the buffer mechanism 74 includes a guide post and an elastic element, with the guide post extending along the first direction Z. One of the third mounting platform 75 and the second clamping mechanism 73 (such as the first fixing plate 734) is fixedly connected to the guide post, and the other is movably connected to the guide post. The elastic element surrounds the guide post, with one end elastically abutting against the surface of the third mounting platform 75 facing the second clamping mechanism 73, and the other end elastically abutting against the second clamping mechanism 73 in the first direction Z. It can be understood that the elastic element can be a spring, rubber block, rubber sleeve, spring sheet, etc. The guide post can be a bolt, screw, or other structure. Optionally, the buffer mechanism 74 may only include an elastic element (such as a spring), with one end of the elastic element fixedly connected to the third mounting platform 75 and the other end fixedly connected to the second clamping mechanism 73.
[0315] When there is no relative movement between the second clamping mechanism 73 and the third mounting platform 75, the buffer mechanism 74 may have an initial deformation or no deformation. During the closing process, as the cap of the test tube 2004 is tightened, the cap pulls the second clamping mechanism 73 downwards, and the buffer mechanism 74 may change from its initial deformation to a larger deformation, or from no deformation to deformation. During the opening process, as the cap of the test tube 2004 is loosened, the cap presses against the second clamping mechanism 73 and moves upwards, and the buffer mechanism 74 may change from its initial deformation to a smaller deformation. The elastic deformation of the buffer mechanism 74 provides a buffering force to the second clamping mechanism 73 along the first direction Z, assisting the test tube 2004 in opening and closing the cap, improving the accuracy and success rate of opening and closing the cap.
[0316] It is understandable that the buffer mechanism 74 can also be set in the third clamping component 93 without restriction.
[0317] Optionally, as shown in Figures 6 and 7, the test tube holder assembly 90, the third clamping assembly 93, the pipette tip tray assembly 80, and the flash filtration bottle transfer assembly 50 are arranged sequentially along the second direction X. This arrangement facilitates the sequential execution of experimental procedures such as loading, opening, pipetting, and filtration, saving experimental interaction time and resulting in a reasonable structural layout.
[0318] The following describes the specific workflow of the experimental platform 1000 in one embodiment of this application:
[0319] The test tube rack containing the sample solution is moved manually or by robot to the test tube rack placement seat 91, and the flash filtration bottle inner tube tray containing the flash filtration bottle inner tube 2001, the flash filtration bottle outer tube tray containing the flash filtration bottle outer tube 2002, and the pipette tip tray containing the pipette tip 2003 are transferred manually or by robot to the corresponding tray placement position on the experimental platform 1000 to complete the loading work before the experiment.
[0320] Subsequently, the second clamping mechanism 73 of the sampling device 300 clamps the cap of the test tube 2004 from the test tube holder and moves the test tube 2004 to the cap-opening station. The third clamping mechanism 931 at the cap-opening station clamps the tube body of the test tube 2004 and cooperates with the second clamping mechanism 73 to open the test tube 2004. At this time, the outer tube tray and the inner tube tray of the flash filtration flask are located at the pipetting station. The pipetting assembly 60 moves to the pipetting head tray to install pipetting heads 2003 in batches, then moves above the test tube 2004 and extends into the test tube 2004 to aspirate and mix the sample solution. After mixing, the pipetting head 2003 aspirates a certain amount of sample solution from the test tube 2004 and moves above the outer tube 2002 of the flash filtration flask to transfer the sample solution into the outer tube 2002 of the flash filtration flask. After the transfer is completed, the lower pressure plate 67 of the pipetting assembly 60 drives the separator 69 to press down and separate the used pipetting head 2003 from the pipetting assembly 60, thus completing the sampling work.
[0321] Then, the second clamping mechanism 73 moves to the capping station and cooperates with the third clamping mechanism 931 to close the cap on the test tube 2004. After closing the cap, the second clamping mechanism 73 clamps the test tube 2004 and moves it to the test tube holder, returning the test tube 2004 to its original position. Simultaneously, the flash filtration flask transfer assembly 50 moves the flash filtration flask outer tube tray and the flash filtration flask inner tube tray to the flash filtration station. The liquid addition assembly 40 of the flash filtration device 100 moves above the flash filtration flask outer tube 2002 and adds diluent into the flash filtration flask outer tube 2002. After adding the liquid, the first clamping mechanism 31 clamps the flash filtration flask inner tube 2001 from the flash filtration flask inner tube tray and transfers the flash filtration flask inner tube 2001 above the flash filtration flask outer tube 2002, while simultaneously allowing part of the flash filtration flask inner tube 2001 to extend into the flash filtration flask outer tube 2002. Then, the first lifting mechanism 14 drives the filter press plate 21 to press down and press against the inner tube 2001 of the flash filtration bottle, performing the filter press action. After the filter press is completed, the filter press plate 21 moves up, and the flash filtration bottle transfer assembly 50 drives the outer tube tray and the inner tube tray of the flash filtration bottle to the pipetting station, thus completing the single batch experiment process.
[0322] The experimental platform 1000 can repeat the above process until all sample solutions of the same batch have been sampled and flash filtered.
[0323] In the description of the embodiments of this application, it should be noted that the orientation or positional relationship of the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and other indicators are based on the orientation or positional relationship of the drawings, and are only for the convenience of describing this application and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.
[0324] The above-disclosed embodiments are merely preferred embodiments of this application and should not be construed as limiting the scope of this application. Those skilled in the art will understand that all or part of the processes for implementing the above embodiments and equivalent variations made in accordance with the claims of this application are still within the scope of this application.
Claims
1. A flash filtration apparatus, characterized by, include: Support components; A filter press assembly includes a filter press plate, the filter press plate being slidably connected to the support assembly and capable of moving along a first direction; The first clamping assembly includes a first clamping tube mechanism, which is slidably connected to the support assembly and is movable along a second direction, the second direction intersecting the first direction; The first clamping mechanism is used to clamp and move the inner tube of the flash filter bottle and extend part of the inner tube of the flash filter bottle into the outer tube of the flash filter bottle. The filter press plate is used to press the inner tube of the flash filter bottle into the outer tube of the flash filter bottle.
2. The flash filtration device of claim 1, wherein, The support assembly includes a support column and a movable plate. The support column extends along the first direction, and the movable plate is slidably connected to the support column and can move along the first direction. The filter press plate is slidably connected to the movable plate and can also move along the second direction; the first clamping tube mechanism is slidably connected to the movable plate and can move along the second direction, and the first clamping tube mechanism can also move relative to the filter press plate along the first direction.
3. The flash filtration device of claim 2, wherein, The support assembly further includes a top plate and a first lifting mechanism. The top plate is fixedly connected to the support column, and the first lifting mechanism is disposed on the top plate and connected to the movable plate. The first lifting mechanism is used to drive the movable plate to move along the first direction.
4. The flash filtration device of claim 2 or 3, wherein, The filter press assembly further includes a first translation mechanism and a first slide. The first translation mechanism is disposed on the movable plate, the first slide is slidably connected to the movable plate along the second direction, and the filter press plate is connected to the first slide. The first translation mechanism is connected to the first slide and is used to drive the first slide to move along the second direction.
5. The flash filtration device of claim 4, wherein, The first clamping assembly further includes a guide shaft, a second slide, and a second lifting mechanism. The guide shaft extends along the first direction, and one end of the guide shaft is connected to the first slide and the other end is connected to the filter plate. The second slide is slidably connected to the guide shaft. The first tube clamping mechanism is connected to the second slide. The second lifting mechanism is disposed on the first slide and connected to the second slide. The second lifting mechanism is used to drive the second slide to move along the first direction.
6. The flash filtration device of claim 1, wherein, The support assembly includes a support frame and a first lifting mechanism disposed on the support frame. The first lifting mechanism is connected to the filter press plate and is used to drive the filter press plate to move along the first direction.
7. The flash filtration device of claim 6, wherein, The first clamping mechanism is slidably connected to the filter press plate and can move along the second direction; the filter press assembly further includes a first translation mechanism, which is disposed on the filter press plate, connected to the first clamping mechanism, and used to drive the first clamping mechanism to move along the second direction.
8. The flash filtration device of claim 3, wherein, The filter press assembly further includes a pressure sensor disposed on the movable plate, the pressure sensor being used to abut against the first lifting mechanism to obtain pressure data; or, the pressure sensor is disposed on the first lifting mechanism, the pressure sensor being used to abut against the movable plate to obtain pressure data; wherein, the pressure data is used to characterize the movement distance of the filter press plate along the first direction.
9. The flash filtration device of claim 8, wherein, The first lifting mechanism includes a first lifting drive component and a first transmission rod. The first lifting drive component is disposed on the top plate, and the first transmission rod is connected to the movable plate. The first lifting drive component and the first transmission rod are in a transmission cooperation to drive the movable plate to move along the first direction. The first lifting mechanism further includes a first floating joint and a second floating joint. The first floating joint is connected to the first transmission rod, and the second floating joint is fixedly connected to the movable plate and movably connected to the first transmission rod. The pressure sensor is disposed on the first floating joint or the second floating joint and is located between the first floating joint and the second floating joint.
10. The flash filtration device of claim 5, wherein, The first clamping mechanism includes a first clamping drive, a first clamping part and a second clamping part. The first clamping drive is disposed on the second slide. At least one of the first clamping part and the second clamping part is connected to the first clamping drive. The first clamping drive is used to cause the first clamping part and the second clamping part to move relative to each other to clamp the inner tube of the flash filter bottle.
11. The flash filtration device of claim 10, wherein, The first clamping part includes a first mounting plate and multiple sets of first fingers, the multiple sets of first fingers being spaced apart on the first mounting plate, and each set of first fingers including at least one first finger; the second clamping part includes a second mounting plate and multiple sets of second fingers, the multiple sets of second fingers being spaced apart on the second mounting plate, and each set of second fingers including at least one second finger; the multiple sets of first fingers and the multiple sets of second fingers correspond one-to-one, and the first fingers and the second fingers are used to move relative to each other to clamp the inner tube of the flash filter bottle.
12. The flash filtration device of claim 10, wherein, The first clamping mechanism further includes a first transmission component and a second transmission component. The first clamping drive component is connected to the first transmission component and the second transmission component respectively. The first transmission component is fixedly connected to the first clamping part, and the second transmission component is fixedly connected to the second clamping part. The first clamping drive component is used to drive the first transmission component and the second transmission component to move in opposite directions. At least one of the first transmission member and the second transmission member includes a rack.
13. The flash filtration device of any one of claims 1-12, wherein, The flash filtration device further includes a liquid addition assembly, which is connected to the pressure filtration assembly and is used to add sample liquid or diluent to the outer tube of the flash filtration bottle; the liquid addition assembly includes a liquid addition needle and a liquid addition pump, the liquid addition needle is connected to the pressure filtration plate, and the liquid addition pump is connected to the liquid addition needle and is used to output sample liquid or diluent to the liquid addition needle.
14. The flash filtration device of claim 13, wherein, The liquid dosing assembly also includes a cleaning mechanism, which includes a cleaning tank and a cleaning pump. The cleaning pump is connected to the cleaning tank. The cleaning tank is used to contain at least a portion of the liquid dosing needle and to hold cleaning waste liquid. The cleaning pump is used to discharge the cleaning waste liquid from the cleaning tank.
15. The flash filter device according to any one of claims 1-14, characterized in that, The flash filtration device further includes a flash filtration bottle transfer assembly, which includes a flash filtration bottle tray placement seat for holding the inner tube and / or the outer tube of the flash filtration bottle.
16. The flash filter device according to claim 15, characterized in that, The flash filter bottle tray placement seat includes a first tray placement seat and a second tray placement seat, the first tray placement seat and the second tray placement seat are arranged along the second direction, one of the first tray placement seat and the second tray placement seat is used to hold the inner tube of the flash filter bottle, and the other is used to hold the outer tube of the flash filter bottle; The first tray holder and the second tray holder are spaced apart in the first direction, and the first tray holder is closer to the filter press plate in the first direction than the second tray holder.
17. The flash filter device according to claim 15, characterized in that, The filter press plate and the first clamping mechanism are spaced apart along a third direction. The flash filter bottle tray placement seat includes a first tray placement seat and a second tray placement seat. The first tray placement seat and the second tray placement seat are arranged along the third direction. One of the first tray placement seat and the second tray placement seat is used to hold the inner tube of the flash filter bottle, and the other is used to hold the outer tube of the flash filter bottle. The third direction intersects with both the first direction and the second direction.
18. The flash filter device according to any one of claims 15-17, characterized in that, The flash filter bottle transfer assembly further includes a first moving mechanism, which is connected to the flash filter bottle tray placement seat and is used to drive the flash filter bottle tray placement seat to move along the second direction and / or a third direction, wherein the third direction intersects both the first direction and the second direction.
19. The flash filter device according to claim 18, characterized in that, The flash filtration device further includes a baffle plate disposed on the support assembly and spaced apart from the flash filtration bottle tray placement seat in the first direction. The baffle plate has a through hole along the first direction, the diameter of which is smaller than the outer diameter of the inner tube of the flash filtration bottle. The flash filtration bottle tray placement seat can be moved to the baffle plate under the drive of the first moving mechanism.
20. An experimental platform, characterized in that, It includes a base and a flash filter device as described in any one of claims 1 to 19, wherein a support assembly of the flash filter device is mounted on the base.
21. The experimental platform according to claim 20, characterized in that, The experimental platform also includes a sampling device, which includes a pipetting assembly for transferring sample liquid or diluent into the outer tube of the flash filtration bottle, or for extracting filtrate from the inner tube of the filtered flash filtration bottle.
22. The experimental platform according to claim 21, characterized in that, The support assembly includes a support column, a top plate, and a side plate. The support column extends along the first direction. The top plate is fixedly connected to the support column, and the side plate is fixedly connected to the top plate and / or the support column. The pipetting assembly includes a pipette tip mounting base and a pipetting pump. The pipette tip mounting base is used to mount a pipette tip, and the pipetting pump is connected to the pipette tip and transfers the sample solution or diluent to the outer tube of the flash filtration bottle through the pipette tip. The sampling device further includes a second translation mechanism and a third slide. The second translation mechanism is disposed on the side plate, and the third slide is slidably connected to the side plate along the second direction or the third direction. The second translation mechanism is connected to the third slide and is used to drive the third slide to move relative to the side plate. The pipetting assembly is slidably connected to the third slide and is capable of moving relative to the third slide along the first direction; The pipetting assembly further includes a fourth slide and a third lifting mechanism. The third lifting mechanism is disposed on the third slide. The fourth slide is slidably connected to the third slide along the first direction. The pipetting head mounting base is connected to the fourth slide. The third lifting mechanism is connected to the fourth slide and is used to drive the fourth slide to move along the first direction.
23. The experimental platform according to claim 22, characterized in that, The third slide is slidably connected to the side plate along the second direction; the pipetting assembly also includes a first mounting platform and a pitch-changing mechanism, and there are multiple pipetting head mounting seats. The first mounting platform is fixedly connected to the fourth slide, and the multiple pipetting head mounting seats are slidably connected to the first mounting platform and can move along the third direction. The pitch-changing mechanism is disposed on the first mounting platform and connected to the multiple pipetting head mounting seats. The pitch-changing mechanism is used to drive the pipetting head mounting seats to move along the third direction to adjust the distance between any two adjacent pipetting head mounting seats.
24. The experimental platform according to claim 23, characterized in that, The pitch-changing mechanism includes a pitch-changing drive and an adjusting plate. The pitch-changing drive is disposed on the first mounting platform. The adjusting plate is connected to the pitch-changing drive and is movably connected to the adjusting plate. The pitch-changing drive is used to drive the adjusting plate to move in the first direction, so as to drive the multiple pipette head mounting seats to move along the third direction.
25. The experimental platform according to claim 23, characterized in that, The pipetting assembly further includes a lower pressure plate, a lower pressure mechanism, and multiple separating components. The separating components are disposed on the lower pressure plate and slidably connected to the lower pressure plate. Each of the multiple separating components corresponds to a multiple pipetting head mounting base and can move synchronously with the pipetting head mounting base along the third direction. The separating components can also move relative to the pipetting head mounting base along the first direction. The lower pressure mechanism is disposed on the first mounting platform and connected to the lower pressure plate. The lower pressure mechanism is used to drive the separating components to move along the first direction to separate the pipetting head and the pipetting head mounting base.
26. The experimental platform according to any one of claims 22-25, characterized in that, The sampling device further includes a second clamping assembly, which is connected to the fourth slide table and is used to clamp and move the test tube, which is used to hold the sample liquid or diluent. The second clamping assembly includes a second mounting platform, a fourth lifting mechanism, and a second tube clamping mechanism. The second mounting platform is fixedly connected to the fourth slide. The fourth lifting mechanism is disposed on the second mounting platform and connected to the second tube clamping mechanism. The fourth lifting mechanism is used to drive the second tube clamping mechanism to move relative to the second mounting platform along the first direction. The second tube clamping mechanism is used to clamp the test tube.
27. The experimental platform according to claim 26, characterized in that, The second clamping mechanism includes a second clamping drive, a third clamping part, and a fourth clamping part. The second clamping drive is connected to the fourth lifting mechanism. At least one of the third clamping part and the fourth clamping part is connected to the second clamping drive. The second clamping drive is used to cause the third clamping part and the fourth clamping part to move relative to each other to clamp the test tube.
28. The experimental platform according to claim 27, characterized in that, The third clamping part includes a third mounting plate and multiple sets of third fingers, the multiple sets of third fingers being spaced apart on the third mounting plate, and each set of third fingers including at least one third finger; the fourth clamping part includes a fourth mounting plate and multiple sets of fourth fingers, the multiple sets of fourth fingers being spaced apart on the fourth mounting plate, and each set of fourth fingers including at least one fourth finger; the multiple sets of third fingers and the multiple sets of fourth fingers correspond one-to-one, and the third fingers and the fourth fingers are used to move relative to each other to clamp the test tube.
29. The experimental platform according to claim 28, characterized in that, The third clamping part further includes a mounting shaft, a limiting ring, and a preload spring. The mounting shaft is connected to the third mounting plate and extends along the moving direction of the third clamping part. Each group of third fingers is slidably connected to the mounting shaft. Each group of third fingers is provided with a limiting ring on the side opposite to the corresponding fourth finger. The limiting ring is sleeved on the mounting shaft and connected and fixed to the mounting shaft. Each group of third fingers is provided with a preload spring between itself and the corresponding limiting ring. One end of the preload spring elastically abuts against the limiting ring, and the other end elastically abuts against the third finger.
30. The experimental platform according to claim 27, characterized in that, The second clamping mechanism further includes a third transmission member and a fourth transmission member. The second clamping drive member is connected to the third transmission member and the fourth transmission member respectively. The third transmission member is connected to the third clamping part, and the fourth transmission member is connected to the fourth clamping part. The second clamping drive member is used to drive the third transmission member and the fourth transmission member to move in opposite directions.
31. The experimental platform according to claim 26, characterized in that, The second clamping assembly further includes a buffer mechanism and a third mounting platform. The third mounting platform is connected to the fourth lifting mechanism. The buffer mechanism is disposed between the third mounting platform and the second clamping mechanism and is used to move the second clamping mechanism relative to the third mounting platform in the first direction.
32. The experimental platform according to claim 21, characterized in that, The sampling device further includes a pipette tray assembly, which includes a pipette tray placement seat and a second moving mechanism. The pipette tray placement seat is slidably connected to the base and is movable along the second direction and / or the third direction. The second moving mechanism is disposed on the base and connected to the pipette tray placement seat. The second moving mechanism is used to drive the pipette tray placement seat to move relative to the base. The pipette tray placement seat is used to hold the pipette.
33. The experimental platform according to claim 32, characterized in that, The pipette tray assembly further includes a pipette mounting bracket connected to the second moving mechanism. The pipette tray placement seat is disposed on the pipette mounting bracket, and there is a clearance space between the pipette mounting bracket and the base. The clearance space is capable of accommodating at least a portion of the flash filtration bottle tray placement seat.
34. The experimental platform according to claim 26, characterized in that, The sampling device further includes a test tube holder assembly, which includes a test tube holder placement base and a test tube mounting rack. The test tube mounting rack is mounted on the base, and the test tube holder placement base is disposed on the test tube mounting rack. The test tube holder base is used to hold the test tubes. The test tube holder assembly further includes a third moving mechanism, which is disposed on the test tube mounting frame and connected to the test tube holder placement seat. The third moving mechanism is used to drive the test tube holder placement seat to move along the second direction and / or the third direction.
35. The experimental platform according to claim 34, characterized in that, The sampling device further includes a third clamping assembly, which is disposed near the test tube holder assembly and is used to open and close the cap of the test tube; The third clamping assembly includes a third tube clamping mechanism, which is used to clamp the tube body of the test tube and rotate it about a first axis. The third tube clamping mechanism can cooperate with the second tube clamping mechanism to open or close the test tube.
36. The experimental platform according to claim 35, characterized in that, The third clamping mechanism includes a third clamping drive, a finger mounting base, and a plurality of fifth fingers. The third clamping drive is disposed on the finger mounting base. The plurality of fifth fingers are spaced apart circumferentially along the finger mounting base and are slidably connected to the finger mounting base. The third clamping drive is connected to the fifth fingers and is used to drive the fifth fingers to move radially along the finger mounting base to clamp the tube body of the test tube.
37. The experimental platform according to claim 35 or 36, characterized in that, The third clamping mechanism comprises multiple components. The third clamping assembly further includes a rotary drive, a first gear, and a second gear. The rotary drive is connected to the first gear. Each third clamping mechanism is connected to the second gear, and the second gear is coaxially arranged with the third clamping mechanism. The first gear meshes with one of the second gears, and two adjacent second gears mesh. The rotary drive is used to drive the first gear to rotate, thereby driving multiple third clamping mechanisms to rotate synchronously around the first axis through the second gear.
38. The experimental platform according to claim 37, characterized in that, A magnet mounting plate is provided on the side of the test tube mounting rack near the third clamping assembly. The magnet mounting plate extends toward the arrangement direction of the multiple third tube clamping mechanisms. Multiple magnets are spaced apart on the magnet mounting plate, and each magnet corresponds to one of the multiple third tube clamping mechanisms.