A liquid composition of asulam

Abstract

The present invention relates to a liquid composition of asulam or its salts thereof, and processes for preparing the same.

Description

[0001] A LIQUID COMPOSITION OFASULAM

[0002] FIELD OF THE INVENTION:

[0003] The present invention relates to a liquid composition of asulam or its salts thereof, and processes for preparing the same.

[0004] BACKGROUND OF THE INVENTION:

[0005] Asulam, also known as methyl V-(4-aminophenyl)sulfonylcarbamate), is a broadspectrum carbamate herbicide. Asulam is a plant growth inhibitor which inhibits folate synthesis by suppression of dihydropteroate synthase (DHPS) in plants. The structure of asulam is represented as:

[0006]

[0007] Asulam is especially useful for post-emergence control of perennial grasses in crops such as sugarcane, soybean, cotton, etc. It provides effective control for a wide variety of herbicide-resistant and herbicide-tolerant weeds while reducing phytotoxicity in crops. Asulam or its salts such as alkali metal salt (like sodium and potassium), ammonium salt, amine salt (like diethanolamine, triethanolamine, octylamine, morpholine and dioctyl methylamine) and alkaline earth metal salts (like calcium and magnesium) are known to possess herbicidal properties. Asulam, active against monocotyledonous and dicotyledonous weeds, is of substantial commercial importance, particularly because of its low toxicity to mammals, birds, fish and wildlife in general, and has a short soil persistence.Generally, liquid formulations are the most frequently used pesticide products and permit extensive formulation development through the inclusion of optimised solvents and surfactants, allowing for the optimisation of biological activity on the basis of an understanding of plant, pathogen and pest biology. Liquid formulations may be classified on the basis of the aqueous or non-aqueous solubility of their constituent active ingredients. Liquid formulations have certain disadvantages such as when the liquid formulation attains saturation, the active ingredient may crystallize out. Another problem with liquid formulation is that when prepared in combination with other active ingredient sometimes leads to incompatibility and degradation of one of the active ingredients thereby resulting in poor efficacy. This challenge can be overcome by usage of stabilizers, which will successfully retain the integrity of the active(s) in the formulation and provide enhanced stability.

[0008] Therefore, there still exists a need to develop a commercially viable, efficient, liquid composition of asulam or its salts thereof, which is user-friendly, stable and economic.

[0009] OBJECTIVES OF THE INVENTION:

[0010] It is an objective of the present invention to provide a liquid composition of asulam or its salts thereof.

[0011] It is an objective of the present invention to provide a liquid composition of asulam or its salts thereof, which is stable and economic.

[0012] It is another objective of the present invention to provide a liquid composition comprising at least about 100 g / L of asulam or its salts thereof, with respect to the total composition.

[0013] It is yet another objective of the present invention to provide a process for preparation of a liquid composition of asulam or its salts thereof.It is yet another object of the present invention to provide a method for controlling undesired vegetation / weeds by applying a liquid composition of asulam or its salts thereof.

[0014] SUMMARY OF THE INVENTION:

[0015] In an aspect of the present invention, there is provided a liquid composition of asulam or its salts thereof.

[0016] In another aspect of the present invention, there is provided a liquid composition comprising at least about 100 g / L of asulam or its salts thereof, with respect to the total composition.

[0017] In another aspect of the present invention, there is provided a liquid composition comprising:

[0018] (a) at least about 100 g / L of asulam or its salts thereof; and

[0019] (b) at least one stabilizer.

[0020] In another aspect, the present invention provides a process for preparation of a liquid composition comprising at least about 100 g / L of asulam or its salts thereof.

[0021] In another aspect, the present invention provides use of a liquid composition comprising at least about 100 g / L of asulam or its salts thereof; for controlling growth of undesired vegetation / weeds.

[0022] In another aspect, the present invention provides a method for controlling growth of undesired vegetation / weeds, said method comprising applying a liquid composition comprising at least about 100 g / L of asulam or its salts thereof.DETAILED DESCRIPTION OF THE INVENTION:

[0023] The following description is provided to assist in a comprehensive understanding of exemplary embodiments of the invention. It includes various specific details to assist in that understanding but these are to be regarded as merely exemplary. Accordingly, those of ordinary skill in the art will recognize that various changes and modifications of the embodiments described herein can be made without departing from the scope of the invention. In addition, descriptions of well-known functions and constructions are omitted for clarity and conciseness. The terms used in the following description and claims are not limited to the bibliographical meanings but are merely used by the inventor to enable a clear and consistent understanding of the invention. Accordingly, it should be apparent to those skilled in the art that the following description of exemplary embodiments of the present invention are provided for illustration purpose only and not for limiting the scope of the invention as defined by the appended claims and their equivalents.

[0024] For the purposes of the present invention, it is to be understood that the invention may assume various alternative variations and step sequences, except where expressly specified to the contrary. Moreover, other than in any operating examples, or where otherwise indicated, all numbers expressing, for example, quantities of materials / ingredients used in the specification are to be understood as being modified in all instances by the term “about”. Thus, before describing the present invention in detail, it is to be understood that this invention is not limited to particularly exemplified systems or process parameters that may of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Prior to setting forth the present subject matter in detail, it may be helpful to provide definitions of certain terms used herein.Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of the invention, suitable methods and materials are described herein.

[0025] As used herein, the terms “comprising”, “including”, “having”, “containing”, “involving” and the like are to be understood to be open-ended, i.e., to mean including but not limited to. The terms “preferred” and “preferably” refer to embodiments of the invention that may afford certain benefits, under certain circumstances. The aspects and embodiments described herein shall also be interpreted to replace the clause “comprising” with either “consisting of’ or with “consisting essentially of’ or with “consisting substantially of’.

[0026] “About” or “approximately” as used herein is inclusive of the stated value and means within an acceptable range of deviation for the particular value as determined by one of ordinary skill in the art, considering the measurement in question and the error associated with measurement of the particular quantity (i.e., the limitations of the measurement system). For example, “about” can mean within one or more standard deviations, or within ±10% or ±5% of the stated value, or within ±10 or ±5 units of the stated value.

[0027] The use of the terms “a”, “an” and “the” and similar referents (especially in the context of the following claims) are to be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context. The terms first, second etc., as used herein are not meant to denote any particular ordering, but simply for convenience to denote a plurality of, for example, layers.

[0028] All methods described herein can be performed in a suitable order unless otherwise indicated herein or otherwise clearly contradicted by context. The use of any and all examples, or exemplary language (e.g., “such as”), is intended merely to betterillustrate the invention and does not pose a limitation on the scope of the invention unless otherwise claimed. No language in the specification should be construed as indicating any non-claimed element as essential to the practice of the invention as used herein.

[0029] While the invention has been described with reference to an exemplary embodiment, it will be understood by those skilled in the art that various changes may be made, and equivalents may be substituted for elements thereof without departing from the scope of the invention. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the invention without departing from the essential scope thereof. Therefore, it is intended that the invention is not limited to the particular embodiment disclosed as the best mode contemplated for carrying out this invention, but that the invention will include all embodiments falling within the scope of the appended claims.

[0030] As used herein the term “plant” or “crop” refers to whole plants, plant organs (e.g., leaves, stems, twigs, roots, trunks, limbs, shoots, fruits etc.), plant cells, or plant seeds. This term also encompasses plant crops such as fruits. The term “plant” may further include the propagation material thereof, which may include all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers, which can be used for the multiplication of the plant. This includes seeds, tubers, spores, corms, bulbs, rhizomes, sprouts basal shoots, stolons, and buds and other parts of plants, including seedlings and young plants, which are to be transplanted after germination or after emergence from soil.

[0031] The term “locus” as used herein denotes the vicinity or area designated for growth of a desired crop, and in which control of the growth and / or spread of undesirable vegetation is desired. The locus includes the vicinity of desired crop plants wherein undesirable vegetation growth has either occurred, is most likely to occur, or is yet to occur.The term “plant propagation material” is understood to denote generative parts of a plant, such as seeds, vegetative material such as cuttings or tubers, roots, fruits, tubers, bulbs, rhizomes and parts of plants, germinated plants and young plants which are to be transplanted after germination or after emergence from the soil. These young plants may be protected before transplantation by a total or partial treatment by immersion.

[0032] Subsequently, the term “herbicide” encompasses herbicides as far as this does not otherwise emerge from the context. The term herbicide as used herein denotes a compound which controls or modifies the growth of undesired weeds / plants.

[0033] The term “herbicidally effective amount” indicates the quantity of such a compound or combination of such compounds which is capable of controlling or modifying effect on the growth of harmful plants / undesired vegetation / weeds. Controlling effects include all deviation from natural development, for example: killing, retardation, leaf bum, albinism, dwarfism, etc.

[0034] The terms “excipient” or “additive” mean inactive substance that forms a part of the composition. The terms “excipient” or “additive” mean essentially the same thing and can be used interchangeably.

[0035] As used herein, the term “improving plant growth” results in an increase in either the yield, as described above, or the vigour of the plant, as described above, or both the yield and the vigour of the plant. Improvement in plant vigour means that certain traits are improved qualitatively or quantitatively when compared with the same trait in a control plant which has been grown under the same conditions in the absence of the method of the invention. Such traits include, but are not limited to, early and / or improved germination, improved emergence, the ability to use less seeds, increased root growth, a more developed root system, increased root nodulation, increased shoot growth, increased tillering, stronger tillers, more productive tillers, increased or improved plant stand, less plant verse (lodging), anincrease and / or improvement in plant height, an increase in plant weight (fresh or dry), bigger leaf blades, greener leaf colour, increased pigment content, increased photosynthetic activity, earlier flowering, longer panicles, early grain maturity, increased seed, fruit or pod size, increased pod or ear number, increased seed number per pod or ear, increased seed mass, enhanced seed filling, less dead basal leaves, delay of senescence, improved vitality of the plant, increased levels of amino acids in storage tissues and / or less inputs needed (e.g. less fertiliser, water and / or labour needed). A plant with improved vigour may have an increase in any of the aforementioned traits or any combination or two or more of the aforementioned traits. Improvement in plant growth means that certain traits are improved qualitatively or quantitatively when compared with the same trait in a control plant which has been grown under the same conditions in the absence of the method of the invention. Such traits include, but are not limited to, improved visual appearance of the plant, reduced ethylene (reduced production and / or inhibition of reception), improved quality of harvested material, e.g., seeds, fruits, leaves, vegetables (such improved quality may manifest as improved visual appearance of the harvested material) and the like.

[0036] As used herein, the “compositions” are interchangeably referred to as “formulations”.

[0037] As used herein, the term “DM water” refers to demineralized water (or deionized water) which is water with most of its mineral ions, like calcium, magnesium, sodium, and chloride, removed through processes like ion exchange, reverse osmosis, or distillation, making it highly pure and free from dissolved salts, ideal for industrial and scientific uses where mineral buildup or interference is a problem.

[0038] As described herein, the term “SL” refers to soluble concentrate or soluble liquid which is a liquid formulation with active ingredient dissolved in water as the solvent.As used herein the term “g / L” refers to “grams” of the active ingredient in per “Liter” of the composition. The terms “g / L”, “g a.i. / L” and “gai / L” may be used interchangeably.

[0039] Unless otherwise specified, the structures shown include all stereoisomers, enantiomers, diastereomers, geometric isomers, and the like, as understood by one skilled in the art. The compounds and compositions also include, for example, salts, solvates, polymorphs, and the like. As used throughout the invention, asulam or other active ingredients, include their salts, esters, ethers, polymorphs including solvates and hydrates. A salt includes salts that retain the biological effectiveness and properties of the active ingredient, and which are not biologically or otherwise undesirable, and include derivatives of the disclosed compounds in which the parent compound is modified by making inorganic and organic, non-toxic, acid or base addition salts thereof. The salts can be synthesized from the parent compound by conventional chemical methods.

[0040] In an embodiment of the present invention, there is provided a liquid composition of asulam or its salts thereof.

[0041] In an embodiment of the present invention, the liquid composition is selected from the group comprising soluble concentrate (SL), emulsifiable concentrate (EC), suspension concentrate (SC), dispersible concentrate (DC), oil dispersion (OD), microemulsion (ME), concentrated aqueous emulsion (EW), oil-miscible liquid (OL), solution for seed treatment (LS), emulsions for seed treatment (ES), suspension concentrates for seed treatment (FS), emulsion oil-in-water (EW), emulsion water-in-oil (EO), aqueous capsule suspensions (CS), aqueous suspo-emulsion (SE), mixed formulations of CS and SC (ZC), mixed formulations of CS and EW (ZW), mixed formulations of CS and SE (ZE), and ultra-low volume (ULV) liquid.In an embodiment, the liquid composition of asulam or its salts thereof is present in a form of soluble concentrate (SL) formulation.

[0042] In another embodiment of the present invention, there is provided a liquid composition comprising at least about 100 g / L of asulam or its salts thereof, with respect to the total composition.

[0043] In another embodiment of the present invention, there is provided a liquid composition comprising:

[0044] (a) at least about 100 g / L of asulam or its salts thereof; and

[0045] (b) at least one stabilizer.

[0046] In another embodiment of the present invention, there is provided a soluble concentrate (SL) composition comprising:

[0047] (a) at least about 100 g / L of asulam or its salts thereof; and

[0048] (b) at least one stabilizer.

[0049] In an embodiment, said liquid composition comprises at least about 100 g / L of asulam or its salts thereof, preferably at least about 150 g / L of asulam or its salts thereof, preferably at least about 200 g / L of asulam or its salts thereof, preferably at least about 250 g / L of asulam or its salts thereof, preferably at least about 300 g / L of asulam or its salts thereof, preferably at least about 350 g / L of asulam or its salts thereof, and more preferably at least about 400 g / L of asulam or its salts thereof, with respect to the total composition.

[0050] In an embodiment, said liquid composition comprises at least about 100 g / L to at least about 800 g / L of asulam or its salts thereof, with respect to the total composition. In a preferred embodiment, the liquid composition comprises from about 416.32 g / L to about 460.14 g / L of asulam or its salts thereof, with respect to the total composition. In a preferred embodiment, the liquid composition comprises from about 380 g / L to about 420 g / L of asulam or its salts thereof, with respect tothe total composition. In a preferred embodiment, the liquid composition comprises about 400 g / L of asulam or its salts thereof, with respect to the total composition.

[0051] In an embodiment, the composition comprises a stabilizer selected from the group comprising sodium hydroxide, potassium hydroxide, calcium hydroxide, magnesium hydroxide, dimethylamine, diethylamine, or combinations thereof. In a preferred embodiment, the stabilizer is sodium hydroxide.

[0052] In an embodiment, the stabilizer has the ability to prevent unwanted reactions and sedimentation / turbidity. In general, presence of a stabilizer in the composition of the present invention exhibits prolonged shelf stability.

[0053] In an embodiment, the amount of stabilizer in the liquid composition ranges from about 0.1 g / L to about 10 g / L, preferably from about 0.5 g / L to about 8 g / L, and more preferably from about 1 g / L to about 5 g / L, with respect to the total composition. In a preferred embodiment, the amount of stabilizer in the liquid composition ranges from about 3.55 g / L to about 4.80 g / L with respect to the total composition.

[0054] In another embodiment of the present invention, there is provided a liquid composition comprising:

[0055] (a) about 100 g / L to about 800 g / L of asulam or its salts thereof; and

[0056] (b) about 0.1 g / L to about 10 g / L of stabilizer.

[0057] In an embodiment, the liquid composition further comprises at least one pH modifier selected from organic and inorganic water-soluble acid comprising hydrochloric acid, phosphoric acid, citric acid, acetic acid, sulfuric acid, nitric acid, or combinations thereof. In a preferred embodiment, the pH modifier is hydrochloric acid.In an embodiment, the amount of pH modifier in the liquid composition ranges from about 10 g / L to about 100 g / L, preferably from about 20 g / L to about 90 g / L, and more preferably from about 30 g / L to about 80 g / L, and most preferably from about 40 g / L to about 70 g / L, with respect to the total composition. In a preferred embodiment, the amount of pH modifier in the liquid composition ranges from about 48.78 g / L to about 65.99 g / L with respect to the total composition.

[0058] In an embodiment, the soluble concentrate composition comprises:

[0059] (a) about 100 g / L to about 800 g / L of asulam or its salts thereof;

[0060] (b) about 0.1 g / L to about 10 g / L of stabilizer; and

[0061] (c) optionally at least one pH modifier.

[0062] In an embodiment, the soluble concentrate composition comprises:

[0063] (a) about 100 g / L to about 800 g / L of asulam or its salts thereof;

[0064] (b) about 0.1 g / L to about 10 g / L of stabilizer; and

[0065] (c) at least one pH modifier.

[0066] In an embodiment, the soluble concentrate composition comprises:

[0067] (a) about 100 g / L to about 800 g / L of asulam or its salts thereof;

[0068] (b) about 0.1 g / L to about 10 g / L of stabilizer; and

[0069] (c) about 10 g / L to about 100 g / L of pH modifier.

[0070] In an embodiment, the liquid composition may further comprise one or more agrochemically acceptable excipient.

[0071] In an embodiment, said agrochemically acceptable excipient is selected from the group comprising solvent(s), buffering agent(s), neutralizing agent(s), surfactant(s), wetting agent(s), spreading agent(s), tackifier(s), sticker(s), filler(s), thickener(s), emulsifier(s), dispersant(s), sequestering agent(s), anti-settling agent(s), rheology modifier(s), defoaming agent(s), photo-protector(s), anti-freeze agent(s),biocide(s), penetrant(s), mineral or vegetable oil(s), pigment(s), drift control agent(s), or combinations thereof.

[0072] In an embodiment, the liquid composition comprises a solvent selected from water, ethanol, methanol, acetone, or combinations thereof. In a preferred embodiment, the solvent is water.

[0073] In an embodiment, the liquid composition comprising asulam or its salts thereof, can be formulated with at least one additional herbicide(s), tank-mixed with additional herbicide(s) or applied sequentially with the additional herbicide(s).

[0074] In another aspect, the present invention provides a process for preparation of a liquid, soluble concentrate composition of asulam or its salts thereof; the process comprising:

[0075] (a) mixing asulam with at least one stabilizer and optionally a pH modifier and stirring till pH of the mixture reaches 7.5 under nitrogen purging; and

[0076] (b) diluting the mixture with DM water once the pH reaches 7.7; and

[0077] (c) filtering the mixture through a sparkler filter to remove insoluble impurities to obtain a liquid, soluble concentrate composition of asulam.

[0078] In another embodiment, the present invention provides use of a liquid composition comprising at least about 100 g / L of asulam or its salts thereof; for controlling growth of undesired vegetation / weeds.

[0079] In another embodiment, the compositions according to the invention have an outstanding herbicidal activity however, the crop plants of economically important crops such as soybeans, cotton, oilseed rape, sugarbeet, or graminaceous crops such as wheat, barley, rye, oats, sorghum and millet, sugarcane, coffee, tea, cacao, coconut, bananas or maize, only suffer a minor extent of damage, or none at all. This is why the liquid composition according to the invention is highly suitable for selectively controlling undesired vegetation / weeds in plantations of agriculturaluseful crops or in ornamental plantations. Owing to its herbicidal property, the liquid composition according to the invention can also be employed for controlling harmful plants in crops of genetically modified plants which are known.

[0080] In another embodiment, the present invention provides a method for controlling growth of undesired vegetation / weeds, said method comprising applying a liquid composition comprising at least about 100 g / L of asulam or its salts thereof.

[0081] In another embodiment, the present invention furthermore also relates to a method for controlling growth of undesired vegetation / weeds, preferably in crops of plants such as cereals (for example wheat, barley, rye, oats, rice, maize, sorghum and millet), sugar beet, sugarcane, oilseed rape, cotton and soybeans, especially preferably in monocotyledonous crops such as cereals, for example wheat, barley, rye, oats, their hybridization products such as triticale, rice, maize, sorghum and millet. The liquid composition of asulam according to the invention being applied to the harmful plants, plant parts, plant seeds or the area on which the plants grow, for example the area under cultivation. In another embodiment, the plant crops can also have been genetically modified or have been obtained by mutation selection and are preferably tolerant to acetolactate synthase (ALS) inhibitors.

[0082] In view of the above, it will be seen that the several advantages of the disclosure are achieved, and other advantageous results attained. Although the present disclosure has been disclosed in full, it will be understood that numerous additional modifications and variations could be made thereto without departing from the scope of the disclosure.

[0083] The disclosure may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are therefore, to be considered in all respects as illustrative and not restrictive.EXAMPLES:

[0084] Example 1 : Asulam SL composition

[0085]

[0086] Process:

[0087] Asulam was charged to a clean reactor with stirring and hydrochloric acid and sodium hydroxide was added slowly through pump to maintain the pH of the reaction mass become 7.5 under nitrogen purging and the same was maintained for one hour. If the end of reaction met the specification pH 7.7 then the reaction mass was diluted with the calculated amount of DM water. Then reaction mass was filtered through sparkler filter to remove insoluble impurities, to obtain a liquid, soluble concentrate (SL) composition of asulam.

[0088] Example 2: Accelerated stability study with and without stabilizer

[0089] A stability study was conducted to investigate the stability of the composition of asulam SL formulation with and without the stabilizer at accelerated conditions of 14 days, 54°C and the same has been disclosed in Table 1 and Table 2 respectively.

[0090] Table 1: Description of Examples

[0091]

[0092]

[0093] Table 2: Parameters observed for Examples of Table 1

[0094] <

[0095]

[0096] <

[0097]

[0098] <

[0099]

[0100] Example 1 did not show critical deviations in physicochemical analyses even when subjected to accelerated stability for 14 and 28 days at 54°C. The content of asulam was quantified within the range specified for the product and degradation < 2.0% for all temperature conditions.

[0101] Comparative Example 1 showed darkening of colour for samples subjected to temperature of 54°C and degradation <4.1% for all temperature conditions. Comparative Example 2 showed an intense darkening of colour for samples subjected to temperature of 54°C and degradation <3.3% for all temperature conditions.

[0102] Example 3 : Stabilizer screening study with different stabilizers

[0103] A stability study was conducted to investigate the stability of the composition of asulam SL formulation with different (basic) stabilizer at accelerated conditions of 14 days, 54°C and the same has been disclosed in Table 3 and Table 4 respectively.Table 3 : Description of Examples

[0104]

[0105] Table 4: Parameters observed for Examples of Table 3

[0106] <

[0107]

[0108] <

[0109]

[0110] Comparative Example 3 showed degradation <5% at a temperature of 54°C for 14 days, however degradation >5% at a temperature of 54°C for 28 days. Comparative Example 4 showed degradation > 5% for all temperature conditions.

[0111] Based on the examples, it was observed that asulam SL formulation required a basifying agent to control the colour and avoid intense darkening. The basifying agent sodium hydroxide was approved because it maintained the colour of the formulated product within the specification and also maintained degradation of the active ingredient <5%. Although the basifying agents triethanolamine and triisopropanolamine provided excellent maintenance of the yellow colour of the formulation, they failed because they intensified the degradation of the active ingredient >5%.

Claims

CLAIMS:

1. A liquid composition comprising:(a) at least about 100 g / L of asulam or its salts thereof; and(b) at least one stabilizer.

2. The composition as claimed in claim 1, wherein the stabilizer is selected from the group comprising sodium hydroxide, potassium hydroxide, calcium hydroxide, magnesium hydroxide, dimethylamine, diethylamine or combinations thereof.

3. The composition as claimed in claim 2, wherein the stabilizer is sodium hydroxide.

4. The composition as claimed in claim 1, wherein the composition further comprises at least one pH modifier selected from organic and inorganic water- soluble acid comprising hydrochloric acid, phosphoric acid, citric acid, acetic acid, sulfuric acid, nitric acid, or combinations thereof.

5. The composition as claimed in claim 4, wherein the pH modifier is hydrochloric acid.

6. The composition as claimed in claim 1, wherein the composition comprises from about 100 g / L to about 800 g / L of asulam or its salts thereof.

7. The composition as claimed in claim 1, wherein the composition comprises from about 0.1 g / L to about 10 g / L of stabilizer.

8. The composition as claimed in claim 4, wherein the composition comprises from about 48.78 g / L to about 65.99 g / L of pH modifier.

9. The composition as claimed in claim 1, wherein the liquid composition is selected from the group comprising soluble concentrate, emulsifiable concentrate, suspension concentrate, dispersible concentrate, oil dispersion, microemulsion, concentrated aqueous emulsion, oil-miscible liquid, solution for seed treatment, emulsions for seed treatment, suspension concentrates for seed treatment, emulsion oil-in-water, emulsion water-in-oil, aqueous capsule suspensions, aqueous suspo-emulsion, mixed formulations of CS and SC, mixed formulations of CS and EW, mixed formulations of CS and SE, and ultralow volume liquid.

10. The composition as claimed in claim 9, wherein the liquid composition is in a form of a soluble concentrate formulation.

11. A process for preparing a liquid composition, the process comprising:(a) mixing asulam with at least one stabilizer and optionally a pH modifier and stirring till pH of the mixture reaches 7.5 under nitrogen purging; and (b) diluting the mixture with DM water once the pH reaches 7.7; and(c) filtering the mixture through a sparkler filter to remove insoluble impurities to obtain a liquid, soluble concentrate composition of asulam.

12. Use of a liquid composition for controlling weeds, the composition comprising:(a) at least about 100 g / L of asulam or its salts thereof; and(b) at least one stabilizer.

13. A method for controlling weeds comprising applying to a plant or a locus thereof a liquid composition comprising:(a) at least about 100 g / L of asulam or its salts thereof; and(b) at least one stabilizer.

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