Equipment handling module mounting to liquid handling system

Abstract

A mounting structure for securing an equipment handling module to a robot platen of a liquid handling system includes a mounting interface configured to attach the equipment handling module to a surface of the robot platen such that the equipment handling module is cantilevered off an edge of the robot platen. The mounting structure further includes a spring-loaded leveling foot coupled to the equipment handling module and configured to contact a supporting surface beneath the equipment handling module. The spring-loaded leveling foot includes at least one spring configured to support at least a portion of a weight of the equipment handling module.

Description

Docket No. 0083-0034PCT4EQUIPMENT HANDLING MODULE MOUNTING TO LIQUID HANDLING SYSTEMCROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims priority to U.S. Provisional Application No. 63 / 749,228, titled "ROBOTIC LAB WARE MODULE FOR A PIPETTE SYSTEM”, filed January 24, 2025, which is hereby incorporated by reference in its entirety for all purposes.FIELD OF INVENTION

[0002] The present disclosure relates to equipment handling systems for liquid handling systems, and more particularly to mounting systems and methods for connecting an equipment handling module to an enclosure of a pipette system to enable calibrated delivery of labware without requiring position calibration.BACKGROUND

[0003] Liquid handling systems such as pipette systems are used in laboratory settings to automate the handling and distribution of liquids across various receptacles and devices. These systems typically include robotic elements, moveable stages, and selectively couplable pipettes that work together to aspirate and dispense liquids with precision. A pipette robot may include an XYZ gantry, pipettes attached to the gantry, and a deck upon which labware can be situated. The pipette robot can perform various operations with respect to the labware, including accessing, aspirating, and dispensing blood and other liquids held by the labware.

[0004] In many implementations, the pipettes, receptacles, and devices used to react liquid solutions are located within an enclosed space. This enclosure isolates the reactions from the outside environment to help ensure that external objects or contaminants do not interrupt the processes of the liquid handling system or the reactions taking place within the enclosed space. The enclosure may also serve to contain potentially hazardous reagents or biological agents and prevent ultraviolet light from escaping when ultraviolet sterilization modules are employed.

[0005] When processing large numbers of samples, liquid handling systems may exhaust their supply of consumable equipment such as pipette tips, PCR plates, deep well plates, reagent reservoirs, and other labware. In conventional systems, this often requires stopping the system during a protocol to manually add additional labware, which can interrupt workflows and reduce throughput. Equipment handling modules have been developed to address this limitation by providing additional labware capacity that can be delivered into the enclosure during operation.Docket No. G083-0034PCT4

[0006] However, integrating additional devices or modules onto or into a base liquid handling system presents challenges. When adding a new piece of equipment to a liquid handling system, the system typically requires calibration so that the pipette robot can identify where the new equipment is located in XYZ space within the enclosure. This calibration process can be timeconsuming and tedious, which may result in additional time spent by a user to set up the system. If calibration is performed incorrectly, errors or crashes may occur during runs of the system. Additionally, mechanical integration of modules may involve alignment issues, tool requirements for installation, and the potential for hardware such as screws to be lost during the installation process.

[0007] The sealing of the enclosure when modules are attached also presents considerations. The enclosure restricts air and light to preserve airflow within the enclosure and prevent leakage of ultraviolet light or potentially hazardous materials. When openings in the enclosure are used to accommodate equipment handling modules, maintaining the integrity of this seal while also providing for proper installation verification becomes a factor in system design.

[0008] Accordingly, there exists a general desire for improved systems and methods for mounting equipment handling modules to liquid handling systems that address one or more of these considerations.BRIEF DESCRIPTION OF FIGURES

[0009] Non-limiting and non-exhaustive examples are described with reference to the following figures.

[0010] FIG. 1 illustrates a liquid handling system with an equipment handling module attached, according to at least one example.

[0011] FIG. 2 illustrates a perspective view of a liquid handling system with an equipment handling module and transfer module, according to at least one example.

[0012] FIG. 3 illustrates a detail perspective view of a liquid handling system with an equipment handling module, according to at least one example.

[0013] FIG. 4 illustrates a perspective view of an equipment handling module showing a mounting configuration, according to at least one example.

[0014] FIG. 5 illustrates a side view of an equipment handling module with a vertical cabinet and horizontal platen and mounting fasteners, according to at least one example.Docket No. G083-0034PCT4

[0015] FIG. 6 illustrates a bottom perspective view of an equipment handling module with a spring-loaded leveling foot, according to at least one example.

[0016] FIG. 7 illustrates a section view of an equipment handling module showing internal structure and mounting components, according to at least one example.

[0017] FIG. 8 illustrates a section view of an equipment handling module mounted to an enclosure of a liquid handling system, according to at least one example.DETAILED DESCRIPTION

[0018] The following description sets forth exemplary aspects of the present disclosure. It should be recognized, however, that such description is not intended as a limitation on the scope of the present disclosure. Rather, the description also encompasses combinations and modifications to those exemplary aspects described herein.

[0019] The present disclosure relates to systems and methods for mounting and supporting equipment handling modules that interface with liquid handling systems. A liquid handling system may include robotic elements, moveable stages, and selectively couplable pipettes that may be coupled to a moveable stage for aspirating and dispensing liquids. The moveable stage may assist in moving and precisely placing pipettes above receptacles such as reaction containers or devices used to react liquid solutions dispensed by the pipettes. A liquid handling system may include a robot that picks up a tip and attaches the tip to a pipette, and with a tip attached, the liquid handling system can aspirate and dispense liquids using the pipette. A pipette robot may include an XYZ gantry, a pipette attached to the XYZ gantry, and a deck upon which labware can be situated. Liquid access by the pipette robot may involve the robot moving the XYZ gantry about a rigid frame, and the pipette robot may perform various operations with respect to the labware, for instance accessing blood and other liquids held by the labware.

[0020] In various configurations, pipettes, receptacles, and devices used to react liquid solutions may be located within an enclosed space in which reactions may be isolated from any outside environment. The enclosed space may prevent other objects from interrupting the processes of the liquid handling system and the reactions taking place within the enclosed space. When adding a new piece of equipment to a liquid handling system, the system may require calibration such that the system can identify where the new equipment is located in XYZ space within the enclosure. The present disclosure provides solutions for calibrating and providing theDocket No. 0083-0034PCT4location of new equipment to the liquid handling system through mechanical mounting structures that minimize alignment discrepancies and reduce installation complexity.

[0021] A mounting structure for securing an equipment handling module to a robot platen of a liquid handling system may include a mounting interface and a spring-loaded leveling foot. The mounting interface may be configured to attach the equipment handling module to a surface of the robot platen such that the equipment handling module is cantilevered off an edge of the robot platen. The mounting interface may comprise threaded fasteners, bolts, screws, clips, or other suitable attachment mechanisms. The mounting interface may include spring-loaded captive fasteners, quarter-turn fasteners, or cam-lock mechanisms. The mounting interface may be formed from stainless steel, aluminum, titanium, or a suitable polymer material. The mounting interface may provide a rigid connection between the equipment handling module and the robot platen while maintaining tight tolerances for accurate positioning of labware.

[0022] The spring-loaded leveling foot may be coupled to the equipment handling module and configured to contact a supporting surface beneath the equipment handling module. The spring-loaded leveling foot may include at least one spring configured to support at least a portion of a weight of the equipment handling module. The at least one spring may comprise a coil spring, a leaf spring, a torsion spring, a gas spring, or an elastomeric element such as a rubber bushing or a silicone pad. The spring-loaded leveling foot may include a combination of spring types to achieve a desired force profile. The spring-loaded leveling foot may be formed from stainless steel, carbon steel, titanium, or a suitable polymer material. The spring constant of the at least one spring may be selected based on the weight of the equipment handling module and the operational requirements of the liquid handling system.

[0023] The leveling foot may be disposed beneath the equipment handling module and spaced from the horizontal platen. The leveling foot may include a spring mechanism configured to automatically adjust to variations in a height of a supporting surface. The spring mechanism may comprise a coil spring, a gas spring, a belleville washer stack, or an elastomeric element. The spring mechanism may be configured to self-level without manual adjustment by a user. The at least one fastener may be configured to secure the horizontal platen to the deck of the liquid handling system. The at least one fastener may comprise a spring-loaded captive fastener, a threaded bolt, a machine screw, or a quarter-turn fastener. The at least one fastener may beDocket No. 0083-0034PCT4configured to remain coupled to the horizontal platen when in an unfastened state such that the at least one fastener cannot be lost during installation.

[0024] The mounting structures, spring-loaded leveling feet, and captive fastener configurations described herein may be utilized in various systems beyond liquid handling systems. Laboratory automation systems that process biological samples, chemical reagents, or other materials may incorporate similar mounting structures for attaching equipment modules to robotic platforms or processing enclosures. Robotic sample handling systems used in clinical laboratories, research facilities, or industrial testing environments may utilize spring-loaded leveling feet to support cantilevered equipment modules while reducing mechanical stress on mounting interfaces. Diagnostic equipment such as automated analyzers, immunoassay systems, or molecular diagnostic platforms may incorporate captive fastener configurations to enable user installation of accessory modules without requiring trained technicians or specialized tools. The spring-loaded leveling foot configurations may be adapted for use with centrifuge loading systems, automated storage and retrieval systems, or robotic plate handlers that interface with enclosed processing chambers.

[0025] Pharmaceutical processing systems may utilize the mounting structures described herein for attaching dispensing modules, filling stations, or inspection equipment to processing platforms. Compounding systems, vial filling equipment, or blister packaging machines may incorporate spring-loaded leveling feet to support cantilevered modules while accommodating variations in floor surfaces or platform heights. Cell culture automation systems, bioreactor sampling modules, or fermentation monitoring equipment may utilize captive fastener configurations to enable rapid installation and removal of accessory modules without risk of losing hardware components. The spring-loaded leveling foot may be configured to support modules containing liquid reservoirs, reagent containers, or other components that add variable weight to the equipment handling module during operation.

[0026] Referring now to FIG. 1, a liquid handling system 100 is shown in a perspective view with an equipment handling module 104 attached. The liquid handling system 100 includes a liquid handling robot 102 that forms a main body of the system and provides an enclosure within which liquid handling operations may be performed. The liquid handling robot 102 may include internal components such as pipettes, moveable stages, and gantry systems for aspirating and dispensing liquids. The liquid handling robot 102 may be configured to process biological samples, chemicalDocket No. 0083-0034PCT4reagents, or other materials within the enclosed space. The liquid handling robot 102 may include an XYZ gantry system, a gripper arm, or other robotic elements for interacting with labware positioned within the enclosure. The liquid handling robot 102 may be formed from sheet metal, extruded aluminum, or a combination of metal and polymer materials.

[0027] The equipment handling module 104 is positioned adjacent to the liquid handling robot 102 and may be configured to provide labware into the enclosure of the liquid handling robot 102 during processing of samples. The equipment handling module 104 may include a vertical cabinet structure for storing stacks of labware such as tip racks, PCR plates, deep well plates, and reagent reservoirs. The equipment handling module 104 may be enclosed with a door and may include a viewing window for visually observing the level of labware within the vertical cabinet. A transfer module 106 extends from the equipment handling module 104 toward the liquid handling robot 102 and may facilitate the movement of labware from the equipment handling module 104 into the enclosure of the liquid handling robot 102. The transfer module 106 may include mechanical components for transitioning labware from vertical movement within the equipment handling module 104 to horizontal movement into the enclosure.

[0028] A horizontal platen 108 is positioned at a lower portion of the transfer module 106 and provides a surface along which labware may be transported horizontally into the liquid handling robot 102. The horizontal platen 108 may extend through an opening in the enclosure of the liquid handling robot 102 to enable delivery of labware without requiring position calibration. The horizontal platen 108 may support an x-axis carriage for transporting labware into the enclosure. The horizontal platen 108 may be formed from aluminum, stainless steel, titanium, or a rigid polymer material. The horizontal platen 108 may include mounting holes, slots, or other features for receiving fasteners that secure the equipment handling module 104 to the liquid handling robot 102. A mounting interface may be configured to attach the equipment handling module 104 to a surface of a robot platform 110 such that the equipment handling module 104 is cantilevered off an edge of the robot platform 110.

[0029] With continued reference to FIG. 1, the liquid handling robot 102 supports the robot platform 110 that provides a stable base for the system. The robot platform 110 may be formed from sheet metal, cast aluminum, or a rigid composite material. A housing of the liquid handling system 100 that encloses the robot platform 110 includes adjustable feet 112 positioned at corners of the liquid handling system 102 to allow for leveling of the liquid handling robot 102 on variousDocket No. 0083-0034PCT4supporting surfaces. The adjustable feet 112 may comprise threaded posts, screwjacks, or leveling pads that may be manually adjusted by a user to achieve a level orientation of the liquid handling robot 102. The adjustable feet 112 may have an adjustable travel height that accommodates variations in table surfaces or floor surfaces at different installation locations. The adjustable feet 112 may be formed from rubber, polymer, or metal materials.

[0030] A leveling foot 114 is positioned beneath the equipment handling module 104 to support a portion of a weight of the equipment handling module 104. The leveling foot 114 may comprise a spring-loaded leveling foot coupled to the equipment handling module 104 and configured to contact a supporting surface beneath the equipment handling module 104. The spring-loaded leveling foot may include at least one spring configured to support at least a portion of the weight of the equipment handling module 104. The at least one spring may comprise a coil spring, a leaf spring, a torsion spring, a gas spring, or an elastomeric element such as a rubber bushing or a silicone pad. The leveling foot 114 may include a combination of spring types to achieve a desired force profile. The leveling foot 114 may be formed from stainless steel, carbon steel, titanium, or a suitable polymer material. Multiple springs may be used in the leveling foot 114 to provide the desired support characteristics.

[0031] As further shown in FIG. 1, the spring-loaded configuration of the leveling foot 114 enables self-leveling without user adjustment, accommodating variations in table surfaces and the height of the liquid handling robot 102 as set by the adjustable feet 112. The at least one spring of the leveling foot 114 may be selected based on a distance of travel of the spring-loaded leveling foot being at least equal to an adjustable travel height of the adjustable feet 112 of the liquid handling system 100. The spring or springs of the leveling foot 114 may be selected based on the weight of the equipment handling module 104 to support a portion or most of the weight of the equipment handling module 104. The mounting structure may prevent torquing of the robot platform 110 by distributing the weight of the equipment handling module 104 through the spring-loaded leveling foot. The spring constant of the at least one spring may be calculated based on the weight of the equipment handling module 104, the distance from the mounting interface to the leveling foot 114, and the expected range of supporting surface heights. The leveling foot 114 may include adjustment mechanisms, locking features, or damping elements to provide additional control over the support characteristics.Docket No. 0083-0034PCT4

[0032] The installation of an equipment handling module to a liquid handling system may involve interaction between a mounting interface, captive fasteners, and a spring-loaded leveling foot. The mounting interface may be configured to attach the equipment handling module to a surface of a robot platen or platform such that the equipment handling module is cantilevered off an edge of the robot platen. During installation, a user may position the equipment handling module adjacent to the liquid handling system and align the mounting interface with corresponding mounting features on the robot platen. The mounting interface may include a transfer platen or horizontal platen that extends from the equipment handling module and passes through an opening in an enclosure of the liquid handling system. The transfer platen may be configured to be mounted to a platform of the liquid handling system through a plurality of captive fasteners. The captive fasteners may be configured to engage with threaded holes, mounting slots, or other receiving features in the robot platen or platform.

[0033] The transfer platen may include a plurality of captive fasteners configured to secure the transfer platen to the platform. The captive fasteners may be configured to protrude from a surface of the transfer platen when in an unfastened state. The protruding configuration of the captive fasteners in the unfastened state may allow a user to visually identify the fasteners and align the fasteners with corresponding mounting holes in the platform. The captive fasteners may comprise spring-loaded captive screws, quarter-turn fasteners, cam-lock mechanisms, or other fastener types that remain coupled to the transfer platen when in the unfastened state. The captive fasteners may be retained within the transfer platen through retaining rings, shoulder features, or other retention mechanisms that prevent the captive fasteners from separating from the transfer platen. The captive fasteners may be formed from stainless steel, carbon steel, brass, or other suitable materials. The retention of the captive fasteners within the transfer platen ensures that the captive fasteners cannot be lost during installation, which may reduce installation time and prevent hardware from falling into the liquid handling system or onto the supporting surface.

[0034] The captive fasteners may be configured to compress flush with the surface of the transfer platen when secured to the platform. The compression of the captive fasteners may provide a visual indication of proper installation of the equipment handling module to the liquid handling system. When the captive fasteners are properly tightened into the threaded holes or mounting features of the platform, spring elements associated with the captive fasteners may compress and the heads of the captive fasteners may become flush with or recessed below the surface of theDocket No. 0083-0034PCT4transfer platen. The flush configuration of the fastener heads may allow an x-axis carriage or other moving components to travel across the transfer platen without interference from protruding fastener heads. A user may visually inspect the captive fasteners after installation to confirm that the fastener heads are flush with the surface, which may indicate that the fasteners are properly tightened and the equipment handling module is securely mounted. The visual indication may enable a user to install the equipment handling module without requiring trained technicians, specialized tools, or torque measurement equipment.

[0035] The spring-loaded foot may be positioned beneath a vertical cabinet of the equipment handling module at a location spaced from the transfer platen. The spacing between the spring-loaded foot and the transfer platen may distribute the weight of the equipment handling module across multiple support points. The spring-loaded foot may be configured to self-level without manual adjustment by a user to accommodate variations in a height of a supporting surface. The self-leveling operation may occur automatically as the equipment handling module is positioned on the supporting surface and the spring-loaded foot contacts the supporting surface. The spring-loaded foot may include at least one spring that compresses or extends based on the height of the supporting surface relative to the height of the platform of the liquid handling system. The at least one spring may comprise a coil spring, a gas spring, a belleville washer stack, an elastomeric element, or a combination of spring types. The spring-loaded foot may include a contact pad, a foot pad, or a base plate that contacts the supporting surface and distributes the load from the spring-loaded foot across the supporting surface.

[0036] The self-leveling operation of the spring-loaded foot may accommodate variations in table surfaces, floor surfaces, or other supporting surfaces at different installation locations. The supporting surface may not be flat, level, or at a consistent height relative to the platform of the liquid handling system. The liquid handling system may include adjustable feet that a user may have adjusted to level the liquid handling system, which may result in the platform being at a height that differs from a nominal or expected height. The spring-loaded foot may automatically adjust to these variations without requiring a user to manually adjust the height of the spring-loaded foot or to measure the height of the supporting surface. The at least one spring of the spring-loaded foot may have a travel distance that is at least equal to an adjustable travel height of adjustable feet of the liquid handling system. The travel distance may allow the spring-loaded foot to accommodate the full range of height adjustments that may be made to the liquid handlingDocket No. 0083-0034PCT4system. The spring constant of the at least one spring may be selected such that the spring-loaded foot supports a portion of the weight of the equipment handling module while allowing the spring to compress or extend within the available travel distance.

[0037] The spring mechanism of a leveling foot may comprise at least one spring selected based on a weight of an equipment handling module such that the at least one spring supports a portion of the weight of the equipment handling module to reduce a load transferred to a deck through a horizontal platen. The selection of the at least one spring may involve calculating a spring force that substantially offsets the weight of the equipment handling module when the equipment handling module is cantilevered from the deck of a liquid handling system. The spring force calculation may take into account the travel distance of leveling feet on the liquid handling system to ensure proper support across an adjustment range of the liquid handling system. The spring force may be calculated such that the equipment handling module applies approximately zero net weight to a mounting interface when the spring-loaded leveling foot is in contact with a supporting surface. The calculation may involve determining a spring constant, a preload force, and a compression distance that together produce a spring force approximately equal to the weight of the equipment handling module. The spring force calculation may account for the distance from the mounting interface to the leveling foot, the moment arm created by the cantilevered configuration, and the expected range of supporting surface heights.

[0038] The leveling foot may be positioned beneath a vertical cabinet of the equipment handling module, and the vertical cabinet may be configured to store a stack of labware for delivery into an enclosure of the liquid handling system. The positioning of the leveling foot beneath the vertical cabinet may place the leveling foot at a location where the weight of the equipment handling module and the stored labware is concentrated. The spring force provided by the at least one spring may counteract the gravitational force acting on the equipment handling module at the location of the leveling foot. The spring force may be selected such that the equipment handling module is effectively suspended between the mounting interface and the leveling foot, with the spring force balancing the weight of the equipment handling module. The at least one spring may comprise a coil spring, a gas spring, a belleville washer stack, or an elastomeric element selected based on the weight of the equipment handling module and the desired force characteristics. The spring constant and preload of the at least one spring may be selected such that the spring operates within a linear region of the spring force curve across the expected range of compression distances.Docket No. 0083-0034PCT4

[0039] The spring force calculation for the leveling foot may take into account the travel distance of the leveling feet on the liquid handling system to ensure proper support across the adjustment range. The liquid handling system may include adjustable feet that allow a user to level the liquid handling system on various supporting surfaces, and the adjustable feet may have a travel range that corresponds to a range of platform heights. The at least one spring of the leveling foot may be selected such that the spring can compress or extend across a distance at least equal to the travel range of the adjustable feet of the liquid handling system. The spring force may remain within an acceptable range across the full travel distance of the leveling foot, such that the leveling foot continues to support a portion of the weight of the equipment handling module regardless of the height setting of the adjustable feet. The spring constant may be selected such that variations in compression distance across the travel range produce acceptable variations in spring force. The spring force at maximum compression and at minimum compression may both fall within a range that provides adequate support for the equipment handling module without applying excessive force to the supporting surface or to the mounting interface.

[0040] The leveling foot may be designed to accommodate slight weight fluctuations when labware is added to the equipment handling module without causing torque to a robot platen or platform of the liquid handling system. The vertical cabinet may store a stack of labware that adds weight to the equipment handling module during operation, and the weight of the equipment handling module may vary as labware is added to or removed from the vertical cabinet. The spring force provided by the at least one spring may be selected to support the weight of the equipment handling module in an unloaded state, and the spring may compress slightly when labware is added to the vertical cabinet. The slight compression of the spring when labware is added may result in a small increase in spring force that partially offsets the additional weight of the labware. The spring constant may be selected such that the additional compression and the resulting increase in spring force are within acceptable limits that do not cause excessive torque on the mounting interface or the robot platen. The weight fluctuations caused by adding or removing labware may be small relative to the total weight of the equipment handling module, and the spring-loaded leveling foot may absorb these fluctuations without transmitting significant additional load to the mounting interface.

[0041] The spring force may be calculated to make the equipment handling module effectively zero weight on the mounting interface when the equipment handling module is in a nominalDocket No. 0083-0034PCT4operating condition. The nominal operating condition may correspond to the equipment handling module being mounted to the liquid handling system with the leveling foot in contact with the supporting surface and the spring compressed to a nominal compression distance. The spring force at the nominal compression distance may be approximately equal to the weight of the equipment handling module, such that the mounting interface experiences approximately zero net vertical force from the equipment handling module. The mounting interface may experience horizontal forces, shear forces, or moment forces that are transmitted through the fasteners securing the equipment handling module to the deck, but the vertical gravitational force of the equipment handling module may be substantially supported by the spring-loaded leveling foot. The approximately zero weight condition may reduce mechanical stress on the mounting interface, reduce deflection of the deck or robot platen, and reduce wear on the fasteners and mounting features. The spring force calculation may include a safety factor or tolerance band that accounts for manufacturing variations, spring relaxation over time, and variations in the weight of the equipment handling module due to component tolerances.

[0042] Referring to FIG. 2, a liquid handling system 200 is shown in a perspective view with an equipment handling module 204 attached. The liquid handling system 200 includes a liquid handling robot enclosure 202 that houses robotic components and provides an enclosed workspace for liquid handling operations. The liquid handling robot enclosure 202 may be formed from sheet metal panels, extruded aluminum framing, transparent polymer panels, or a combination of materials that provide structural support and visual access to the interior workspace. The liquid handling robot enclosure 202 may include access openings, doors, or ports through which equipment may be transferred into the enclosure. The liquid handling robot enclosure 202 may house pipettes, moveable stages, gantry systems, gripper arms, or other robotic elements for aspirating, dispensing, and manipulating liquids and labware within the enclosed space. The liquid handling robot enclosure 202 may provide isolation from outside environments to prevent contamination of samples or interruption of liquid handling processes.

[0043] The equipment handling module 204 is positioned adjacent to the liquid handling robot enclosure 202 and connects to the enclosure through an access opening. The equipment handling module 204 may include a vertical cabinet for storing stacks of labware such as tip racks, PCR plates, deep well plates, reagent reservoirs, and other equipment. A transfer module 206 extends from the equipment handling module 204 and interfaces with the liquid handling robot enclosureDocket No. 0083-0034PCT4202 to facilitate the transfer of labware between the equipment handling module 204 and the interior of the enclosure. The transfer module 206 may include mechanical components such as carriages, rails, guides, motors, or actuators for moving labware from the equipment handling module 204 into the liquid handling robot enclosure 202. The transfer module 206 may be formed from aluminum extrusions, sheet metal brackets, polymer components, or a combination of materials that provide structural support and smooth motion characteristics.

[0044] A horizontal platen 210 extends from the equipment handling module 204 into the liquid handling robot enclosure 202. The horizontal platen 210 may be configured to attach to a deck of the liquid handling system 200 such that the equipment handling module 204 is cantilevered from the deck. The horizontal platen 210 provides a surface for transporting labware between the equipment handling module 204 and the interior workspace of the liquid handling system 200. The horizontal platen 210 may be formed from aluminum plate, stainless steel sheet, titanium plate, or a rigid polymer material such as acetal, polycarbonate, or glass-filled nylon. The horizontal platen 210 may include mounting holes, threaded inserts, slots, or other features for receiving fasteners that secure the horizontal platen 210 to the deck of the liquid handling system 200. At least one fastener may be configured to secure the horizontal platen 210 to the deck of the liquid handling system 200, and the at least one fastener may comprise spring-loaded captive screws, threaded bolts, machine screws, quarter-turn fasteners, or cam-lock mechanisms.

[0045] An x-axis carriage 212 is positioned on the horizontal platen 210 and may be configured to transport labware along a horizontal axis between the equipment handling module 204 and the interior workspace of the liquid handling system 200. The x-axis carriage 212 may travel along rails, guides, or tracks mounted to the horizontal platen 210. The x-axis carriage 212 may be driven by a lead screw, ball screw, belt drive, rack and pinion, or linear motor. The x-axis carriage 212 may include a platform, tray, or support surface for receiving labware from a Z-axis component within the equipment handling module 204. The x-axis carriage 212 may be formed from aluminum, stainless steel, or a rigid polymer material. The x-axis carriage 212 may include features for engaging with labware such as locating pins, retention clips, magnetic elements, or vacuum ports. Alternative carriage configurations may include multiple carriages operating on parallel tracks, a single carriage with multiple labware positions, or a carriage with adjustable width to accommodate different labware sizes.Docket No. 0083-0034PCT4

[0046] A mounting platform 214 provides a structural connection between the equipment handling module 204 and the liquid handling robot enclosure 202, securing the module in position relative to the enclosure. The mounting platform 214 may comprise a portion of the horizontal platen 210 or may be a separate component that interfaces with both the horizontal platen 210 and the deck of the liquid handling system 200. The mounting platform 214 may include fastener passages, threaded holes, or mounting slots for receiving fasteners that secure the equipment handling module 204 to the deck. The mounting platform 214 may be formed from aluminum plate, stainless steel sheet, or a rigid composite material. Alternative mounting platform configurations may include a flanged mounting plate, a bracket assembly, or an adapter plate that accommodates different deck configurations or enclosure opening sizes. The mounting platform 214 may include alignment features such as locating pins, alignment slots, or registration surfaces that ensure proper positioning of the equipment handling module 204 relative to the liquid handling system 200.

[0047] With continued reference to FIG. 2, a leveling foot 208 is disposed at a base of the transfer module 206 to support a portion of a weight of the equipment handling module 204 and provide stability on a supporting surface. The leveling foot 208 may be spaced from the horizontal platen 210 such that the weight of the equipment handling module 204 is distributed between the mounting connection at the horizontal platen 210 and the leveling foot 208. The leveling foot 208 may include a spring mechanism configured to automatically adjust to variations in a height of the supporting surface. The spring mechanism may comprise a coil spring, a gas spring, a belleville washer stack, an elastomeric element, or a combination of spring types. The leveling foot 208 may have a dimension perpendicular to a direction of the horizontal platen 210 and a direction of x-axis movement to enable leveling across an uneven or not level surface. The leveling foot 208 may include a contact pad, a foot pad, or a base plate that contacts the supporting surface and distributes the load from the leveling foot 208 across the supporting surface.

[0048] The arrangement of components in the liquid handling system 200 enables the equipment handling module 204 to deliver labware into the liquid handling robot enclosure 202 at a precise and repeatable location without requiring position calibration of the equipment handling module 204 relative to the liquid handling system 200. The cantilevered configuration of the equipment handling module 204 from the deck places mechanical loads on the mounting connection, and the leveling foot 208 with the spring mechanism supports a portion of the weightDocket No. 0083-0034PCT4of the equipment handling module 204 to reduce the load transferred to the deck through the horizontal platen 210. The spring mechanism of the leveling foot 208 may be selected based on the weight of the equipment handling module 204 such that the spring mechanism provides a spring force that substantially offsets the weight of the equipment handling module 204. The leveling foot 208 may self-level without manual adjustment by a user, accommodating variations in table surfaces, floor surfaces, or other supporting surfaces at different installation locations. The at least one fastener securing the horizontal platen 210 to the deck may comprise captive fasteners that remain coupled to the horizontal platen 210 when in an unfastened state, preventing loss of hardware during installation and enabling user installation without specialized tools or trained technicians.

[0049] Referring to FIG. 3, a liquid handling system 300 is shown in a perspective view with an equipment handling module 308 attached. The liquid handling system 300 includes a liquid handling robot 302 enclosed within a housing 304. The housing 304 may provide an enclosed space for liquid handling operations and may include walls, panels, doors, or windows that define the boundaries of the enclosed workspace. The housing 304 may be formed from sheet metal panels, extruded aluminum framing, transparent polymer panels such as polycarbonate or acrylic, or a combination of materials that provide structural support, visual access, and environmental isolation. The housing 304 may include seals, gaskets, or overlapping joints that prevent air infiltration, light leakage, or contamination of the enclosed workspace. The liquid handling robot 302 is positioned within the housing 304 and may be configured to interact with labware delivered through an access opening 312 in the housing 304. The liquid handling robot 302 may include pipettes, moveable stages, gantry systems, gripper arms, or other robotic elements for aspirating, dispensing, and manipulating liquids and labware within the enclosed space.

[0050] The access opening 312 is formed in the housing 304 and provides a passage through which equipment may be transferred into the enclosure of the liquid handling robot 302. The access opening 312 may be positioned on a side wall, front wall, rear wall, or top surface of the housing 304 depending on the configuration of the liquid handling system 300 and the arrangement of equipment handling modules. The access opening 312 may have a rectangular shape, a square shape, or other geometric configuration that accommodates the dimensions of labware and transfer components passing through the opening. The access opening 312 may include a frame, flange, or mounting surface that provides attachment points for equipment handling modules, door panels,Docket No. 0083-0034PCT4or cover plates. Alternative access opening arrangements may include multiple access openings positioned on different sides of the housing 304 to accommodate multiple equipment handling modules, or a single elongated access opening that accommodates multiple transfer platens from adjacent equipment handling modules. The access opening 312 may include sealing features such as gaskets, brush seals, or overlapping flanges that maintain environmental isolation when an equipment handling module or door panel is installed.

[0051] The equipment handling module 308 is mounted adjacent to the housing 304 of the liquid handling system 300 and connects to the liquid handling robot 302 through the access opening 312. The equipment handling module 308 may include a vertical cabinet for storing stacks of labware such as tip racks, PCR plates, deep well plates, reagent reservoirs, and other equipment. The equipment handling module 308 includes a horizontal platen 314 that extends from the module toward the access opening 312. The horizontal platen 314 may be configured to pass through the access opening 312 in the housing 304 of the liquid handling system 300. The horizontal platen 314 may extend from a mounting interface of the equipment handling module 308 and may be configured to attach to a deck or platform within the housing 304. The horizontal platen 314 may support an x-axis carriage for transporting labware into the enclosure of the liquid handling robot 302. The horizontal platen 314 may be formed from aluminum plate, stainless steel sheet, titanium plate, or a rigid polymer material such as acetal, polycarbonate, or glass-filled nylon.

[0052] A horizontal transfer platen 316 is positioned to facilitate the transfer of labware from the equipment handling module 308 through the access opening 312 and into the enclosure of the liquid handling robot 302. The horizontal transfer platen 316 may comprise a portion of the horizontal platen 314 or may be a separate component that interfaces with the horizontal platen 314 and extends into the housing 304. The horizontal platen 314 may fill a deck slot of the deck of the liquid handling system. The horizontal platen 314 may also replace the filled deck slot, such that labware can be placed on top of the horizontal platen 314 and may be used as a normal deck slot while still allowing the horizontal transfer platen to transfer labware in that may then be used by the liquid handing system 300. The horizontal transfer platen 316 may provide a surface along which an x-axis carriage travels when transporting labware between the equipment handling module 308 and the interior workspace of the liquid handling system 300. The horizontal transfer platen 316 may include rails, guides, tracks, or bearing surfaces that support and guide the x-axis carriage during horizontal movement. The horizontal transfer platen 316 may include mountingDocket No. 0083-0034PCT4features such as fastener passages, threaded holes, or mounting slots for securing the equipment handling module 308 to the deck of the liquid handling system 300. Alternative horizontal transfer platen configurations may include a cantilevered platen that extends unsupported into the housing 304, a platen with intermediate support brackets, or a platen with adjustable width to accommodate different access opening sizes.

[0053] With continued reference to FIG. 3, the liquid handling system 300 is supported by a leveling foot 306 positioned beneath the housing 304. The leveling foot 306 may comprise an adjustable foot, a fixed foot, or a spring-loaded foot that contacts a supporting surface and provides stability for the liquid handling system 300. The leveling foot 306 may be positioned at a comer, edge, or central location beneath the housing 304 depending on the structural configuration of the liquid handling system 300. The leveling foot 306 may include adjustment mechanisms such as threaded posts, screwjacks, or cam adjusters that allow a user to level the liquid handling system 300 on various supporting surfaces. The leveling foot 306 may be formed from rubber, polymer, metal, or a combination of materials that provide vibration damping, slip resistance, and durability. Multiple leveling feet may be positioned at different locations beneath the housing 304 to provide stable support and allow leveling adjustments across the footprint of the liquid handling system 300.

[0054] The equipment handling module 308 includes a leveling foot 310 that provides support for the module and assists in maintaining proper alignment between the equipment handling module 308 and the liquid handling system 300. The leveling foot 310 may be positioned beneath a vertical cabinet of the equipment handling module 308 at a location spaced from the horizontal platen 314. The leveling foot 310 may include a spring mechanism configured to automatically adjust to variations in a height of a supporting surface. The spring mechanism may comprise a coil spring, a gas spring, abelleville washer stack, an elastomeric element, or a combination of spring types. The leveling foot 310 may be configured to self-level without manual adjustment by a user, accommodating variations in table surfaces, floor surfaces, or other supporting surfaces at different installation locations. The leveling foot 310 may include a contact pad, a foot pad, or a base plate that contacts the supporting surface and distributes the load from the leveling foot 310 across the supporting surface.

[0055] The arrangement of the leveling foot 306 and the leveling foot 310 enables the liquid handling system 300 and the equipment handling module 308 to be positioned on a supportingDocket No. 0083-0034PCT4surface while maintaining proper alignment for labware transfer operations. The leveling foot 306 of the liquid handling system 300 may be adjusted by a user to level the housing 304 on the supporting surface, and the leveling foot 310 of the equipment handling module 308 may automatically adjust to accommodate the height of the housing 304 as set by the leveling foot 306. The spring mechanism of the leveling foot 310 may have a travel distance that is at least equal to an adjustable travel height of the leveling foot 306 of the liquid handling system 300. The spring force provided by the leveling foot 310 may be selected based on the weight of the equipment handling module 308 such that the leveling foot 310 supports a portion of the weight of the equipment handling module 308 to reduce a load transferred to the deck through the horizontal platen 314. The relationship between the leveling foot 306 and the leveling foot 310 allows the equipment handling module 308 to be installed on the liquid handling system 300 without requiring manual adjustment of the leveling foot 310 by a user, regardless of the height setting of the leveling foot 306.

[0056] Alternative housing configurations may include housings with different numbers of access openings, different access opening positions, or different access opening sizes to accommodate various equipment handling module arrangements. The housing 304 may include a single access opening on one side, multiple access openings on one side, or access openings on multiple sides to accommodate one, two, three, four, or more equipment handling modules. The housing 304 may include removable panels, hinged doors, or sliding covers that allow access to the interior workspace for maintenance, cleaning, or manual loading of labware. The housing 304 may include transparent panels or windows that allow visual observation of liquid handling operations within the enclosed space. Alternative housing materials may include stainless steel panels for chemical resistance, powder-coated steel panels for durability, or composite panels for weight reduction. The housing 304 may include ventilation openings, filter ports, or HEPA filter connections for controlling airflow within the enclosed workspace. The housing 304 may include electrical feedthroughs, fluid connections, or communication ports for connecting external equipment to components within the enclosed space.

[0057] Referring to FIG. 4, an equipment handling module 400 is shown in a perspective view illustrating a mounting configuration for attachment to a liquid handling system. The equipment handling module 400 includes a support base 402 that provides a structural foundation for the module and houses various mechanical and electrical components. The support base 402 may beDocket No. 0083-0034PCT4formed from sheet metal, extruded aluminum, cast aluminum, or a rigid polymer material such as glass-filled nylon or polycarbonate. The support base 402 may include internal mounting features, brackets, or reinforcement structures that support components within the equipment handling module 400. The support base 402 may be configured as a welded assembly, a bolted assembly, or an interlocking assembly of multiple components. Alternative support base configurations may include a unitary cast structure, a machined plate assembly, or a composite frame structure that provides structural rigidity while minimizing weight.

[0058] A transfer module 404 extends from the support base 402 and includes transfer components 408 positioned at an upper portion of the transfer module 404. The transfer module 404 may house mechanical components for transitioning labware from vertical movement within a vertical cabinet to horizontal movement into an enclosure of the liquid handling system. The transfer components 408 may facilitate the movement and positioning of labware within the equipment handling module 400 and may include carriages, rails, guides, motors, actuators, or linkage mechanisms. The transfer components 408 may be formed from aluminum, stainless steel, or rigid polymer materials that provide smooth motion characteristics and durability. The transfer module 404 may include a Z-axis component that supports and raises or lowers a stack of labware within the equipment handling module 400. Alternative transfer module configurations may include belt-driven systems, lead screw systems, rack and pinion systems, or pneumatic actuator systems for moving labware between vertical and horizontal orientations.

[0059] A horizontal transfer platen 410 extends from the transfer module 404 and provides a surface for transporting labware between the equipment handling module 400 and an enclosure of the liquid handling system. The horizontal transfer platen 410 may be configured to pass through an access opening in a housing of the liquid handling system and may support an x-axis carriage for transporting labware into the enclosure. The horizontal transfer platen 410 may be formed from aluminum plate, stainless steel sheet, titanium plate, or a rigid polymer material such as acetal, polycarbonate, or glass-filled nylon. The horizontal transfer platen 410 may include rails, guides, tracks, orbearing surfaces that support and guide an x-axis carriage during horizontal movement. The horizontal transfer platen 410 may include mounting holes, threaded inserts, slots, or other features for receiving fasteners that secure the equipment handling module 400 to a deck of the liquid handling system. Alternative horizontal transfer platen configurations may include aDocket No. 0083-0034PCT4cantilevered platen, a platen with intermediate support brackets, or a platen with adjustable dimensions to accommodate different access opening sizes.

[0060] With continued reference to FIG. 4, the horizontal transfer platen 410 includes a plurality of fasteners 412 positioned along a surface of the horizontal transfer platen 410. The fasteners 412 may be arranged to secure the horizontal transfer platen 410 to a deck of the liquid handling system through a four-bolt attachment configuration that bolts directly onto a main bed of a robotic platform. The fasteners 412 may comprise spring-loaded captive fasteners configured to protrude from the surface of the horizontal transfer platen 410 when in an unfastened state and to compress flush with the surface when secured to the deck. The compression of the spring-loaded captive fasteners may provide a visual indication of proper installation of the equipment handling module 400 to the liquid handling system. The spring-loaded captive fasteners may be configured to engage with threaded holes in a robot platen or deck of the liquid handling system. The fasteners 412 may be retained within the horizontal transfer platen 410 through retaining rings, shoulder features, or other retention mechanisms that prevent the fasteners 412 from separating from the horizontal transfer platen 410 when in the unfastened state.

[0061] The horizontal transfer platen 410 may fill a deck slot of the deck of the liquid handling system. The horizontal transfer platen 410 may also replace the filled deck slot, such that labware can be placed on top of the horizontal transfer platen 410 and may be used as a normal deck slot while still allowing the horizontal transfer platen to transfer labware in that may then be used by the liquid handing system. When the fasteners 412 are fully inserted / fastened to the deck of the liquid handling system, a unit of labware may be placed on the horizontal transfer platen 410 as a deck slot.

[0062] The four-bolt attachment configuration may position the fasteners 412 at comers of the horizontal transfer platen 410, along edges of the horizontal transfer platen 410, or in a rectangular pattern that distributes mounting loads across the horizontal transfer platen 410. The fasteners 412 may comprise spring-loaded captive screws, quarter-turn fasteners, cam-lock mechanisms, or threaded bolts with captive washers. The fasteners 412 may be formed from stainless steel, carbon steel, brass, titanium, or other suitable materials that provide corrosion resistance and mechanical strength. Alternative fastener arrangements may include two fasteners, three fasteners, five fasteners, six fasteners, or more fasteners depending on the size of the horizontal transfer platen 410 and the load requirements of the mounting connection. Alternative fastener types may includeDocket No. 0083-0034PCT4machine screws with lock washers, socket head cap screws, hex head bolts, or specialty fasteners designed for captive retention. The fasteners 412 may include features such as knurled heads, wing heads, or tool engagement features that facilitate installation by a user without specialized tools.

[0063] A leveling foot 406 is positioned beneath the support base 402 to support a weight of the equipment handling module 400 and provide stability during operation. The leveling foot 406 may include a spring mechanism configured to automatically adjust to variations in a height of a supporting surface beneath the equipment handling module 400. The spring mechanism may comprise a coil spring, a gas spring, a belleville washer stack, an elastomeric element, or a combination of spring types. The leveling foot 406 may be configured to self-level without manual adjustment by a user, accommodating variations in table surfaces, floor surfaces, or other supporting surfaces at different installation locations. The leveling foot 406 may include a contact pad, a foot pad, or a base plate that contacts the supporting surface and distributes the load from the leveling foot 406 across the supporting surface. The arrangement of the fasteners 412 on the horizontal transfer platen 410 enables direct mounting to the liquid handling system platform, while the leveling foot 406 assists in distributing the weight of the equipment handling module 400 to prevent excessive loading on the mounting connection formed by the fasteners 412.

[0064] Referring to FIG. 5, an equipment handling module 500 is shown in a side view according to at least one embodiment. The equipment handling module 500 includes a vertical cabinet 502 configured to store a stack of labware such as tip racks, PCR plates, deep well plates, reagent reservoirs, and other equipment. The vertical cabinet 502 is positioned at one end of the equipment handling module 500 and provides an enclosed space for holding equipment prior to delivery into a liquid handling system. The vertical cabinet 502 may be formed from sheet metal panels, extruded aluminum framing, or a combination of metal and polymer materials that provide structural support and environmental protection for stored labware. The vertical cabinet 502 may include a door, a viewing window, or access panels that allow a user to load labware into the vertical cabinet 502 and visually observe the level of labware within the vertical cabinet 502. The vertical cabinet 502 may include internal support arms, latches, or notches for supporting labware within the cabinet during storage and dispensing operations.

[0065] A horizontal platen 506 extends from a bottom portion of the vertical cabinet 502 and provides a surface along which labware may be transported from the vertical cabinet 502 into an enclosure of a liquid handling system. The horizontal platen 506 may be configured to support anDocket No. 0083-0034PCT4x-axis carriage that carries labware during transfer operations between the equipment handling module 500 and the liquid handling system. The horizontal platen 506 may be formed from aluminum plate, stainless steel sheet, titanium plate, or a rigid polymer material such as acetal, polycarbonate, or glass-filled nylon. The horizontal platen 506 may include rails, guides, tracks, or bearing surfaces that support and guide an x-axis carriage during horizontal movement. The horizontal platen 506 may include mounting holes, threaded inserts, slots, or other features for receiving fasteners that secure the equipment handling module 500 to a deck of the liquid handling system. Alternative horizontal platen configurations may include a cantilevered platen that extends unsupported into the enclosure, a platen with intermediate support brackets, or a platen with adjustable dimensions to accommodate different access opening sizes.

[0066] With continued reference to FIG. 5, a leveling foot 504 is positioned beneath the vertical cabinet 502 at a location spaced from the horizontal platen 506. The leveling foot 504 may provide support for the equipment handling module 500 and may assist in maintaining stability of the module when connected to a liquid handling system. The leveling foot 504 may include a spring mechanism configured to automatically adjust to variations in a height of a supporting surface beneath the equipment handling module 500. The spring mechanism may comprise a coil spring, a gas spring, a belleville washer stack, a leaf spring, a torsion spring, or an elastomeric element such as a rubber bushing or a silicone pad. The leveling foot 504 may be configured to self-level without manual adjustment by a user, accommodating variations in table surfaces, floor surfaces, or other supporting surfaces at different installation locations. The leveling foot 504 may include a contact pad, a foot pad, or a base plate that contacts the supporting surface and distributes the load from the leveling foot 504 across the supporting surface. The spacing between the leveling foot 504 and the horizontal platen 506 may distribute the weight of the equipment handling module 500 across multiple support points to reduce mechanical stress on the mounting connection.

[0067] A protrusion 508 extends from the horizontal platen 506. The protrusion 508 fits into a cavity such as a calibration cavity in the deck slot into which the horizontal platen 506 is installed. This positions and aids with correct alignment into the deck slot as the protrusion 508 fits into the cavity to provide positive engagement. The upward-facing side of the protrusion 508 forms a cavity in the upper surface of the horizontal platen 506 that acts as the calibration cavity for the deck slot where the module is attached, so the robot may still place labware in the deck slot whereDocket No. 0083-0034PCT4the equipment handling module is installed. The liquid handling system may calibrate for the height of the labware in the deck slot whether or not the horizontal platen 506 is installed.

[0068] As further shown in FIG. 5, a fastener 510 is shown protruding from the horizontal platen 506. The fastener 510 may be configured to secure the equipment handling module 500 to a deck of a liquid handling system. The fastener 510 may comprise a spring-loaded captive fastener configured to protrude from a surface of the horizontal platen 506 when in an unfastened state. The spring-loaded captive fastener may be configured to compress flush with the surface of the horizontal platen 506 when secured to the deck, and the compression may provide a visual indication of proper installation of the equipment handling module 500 to the liquid handling system. The spring-loaded captive fastener may be configured to remain coupled to the horizontal platen 506 when in the unfastened state such that the spring-loaded captive fastener cannot be lost during installation. The retention of the spring-loaded captive fastener within the horizontal platen 506 may be accomplished through retaining rings, shoulder features, captured threads, or other retention mechanisms that prevent the fastener 510 from separating from the horizontal platen 506 when in the unfastened state.

[0069] The protruding configuration of the fastener 510 in the unfastened state may allow a user to visually identify the fastener 510 and align the fastener 510 with corresponding mounting holes in the deck of the liquid handling system. When the fastener 510 is properly tightened into threaded holes or mounting features of the deck, a spring element associated with the fastener 510 may compress and a head of the fastener 510 may become flush with or recessed below the surface of the horizontal platen 506. The flush configuration of the fastener head may allow an x-axis carriage or other moving components to travel across the horizontal platen 506 without interference from protruding fastener heads. A user may visually inspect the fastener 510 after installation to confirm that the fastener head is flush with the surface, which may indicate that the fastener 510 is properly tightened and the equipment handling module 500 is securely mounted. Alternative fastener configurations may include spring-loaded captive screws, quarter-turn fasteners, cam-lock mechanisms, or threaded bolts with captive washers. The fastener 510 may be formed from stainless steel, carbon steel, brass, titanium, or other suitable materials that provide corrosion resistance and mechanical strength. Multiple fasteners may be positioned along the horizontal platen 506 in a pattern that distributes mounting loads across the horizontal platen 506 and provides secure attachment to the deck of the liquid handling system.Docket No. 0083-0034PCT4

[0070] Referring to FIG. 6, an equipment handling module 600 is shown in a bottom perspective view according to at least one embodiment. The equipment handling module 600 includes a vertical cabinet 602 positioned atop a base 604. The vertical cabinet 602 may be configured to store a stack of labware such as tip racks, PCR plates, deep well plates, reagent reservoirs, and other equipment, and may provide an enclosed space for holding equipment prior to delivery into a liquid handling system. The vertical cabinet 602 may be formed from sheet metal panels, extruded aluminum framing, cast aluminum components, or a combination of metal and polymer materials that provide structural support and environmental protection for stored labware. The vertical cabinet 602 may include a door, a viewing window, or access panels that allow a user to load labware into the vertical cabinet 602 and visually observe the level of labware within the vertical cabinet 602. The base 604 may provide structural support for the vertical cabinet 602 and may house various mechanical components such as motors, actuators, sensors, and control electronics.

[0071] The base 604 may be formed from sheet metal, extruded aluminum, cast aluminum, machined plate, or a rigid polymer material such as glass-filled nylon or polycarbonate. The base 604 may include internal mounting features, brackets, reinforcement ribs, or support structures that provide rigidity and support for components within the equipment handling module 600. The base 604 may be configured as a welded assembly, a bolted assembly, a riveted assembly, or an interlocking assembly of multiple components. Alternative base configurations may include a unitary cast structure, a machined plate assembly, a composite frame structure, or a sheet metal enclosure that provides structural rigidity while minimizing weight. The base 604 may include openings, cutouts, or access panels that allow routing of cables, wiring harnesses, or pneumatic tubing between components within the equipment handling module 600.

[0072] A horizontal platen 606 extends from the base 604 and may be configured to transport labware from the vertical cabinet 602 into an enclosure of a liquid handling system. The horizontal platen 606 may support an x-axis carriage for transporting labware between the equipment handling module 600 and an interior workspace of the liquid handling system. The horizontal platen 606 may be formed from aluminum plate, stainless steel sheet, titanium plate, or a rigid polymer material such as acetal, polycarbonate, or glass-filled nylon. The horizontal platen 606 may include rails, guides, tracks, or bearing surfaces that support and guide an x-axis carriage during horizontal movement. The horizontal platen 606 includes a plurality of fastener passagesDocket No. 0083-0034PCT4608 positioned along a surface of the horizontal platen 606. The fastener passages 608 may be configured to receive fasteners for securing the equipment handling module 600 to a deck of the liquid handling system. The fastener passages 608 may comprise through holes, counterbored holes, countersunk holes, or threaded inserts that accommodate various fastener types.

[0073] With continued reference to FIG. 6, the fastener passages 608 may be arranged to align with corresponding mounting points on a platform of the liquid handling system. The fastener passages 608 may receive captive spring-loaded fasteners, threaded bolts, machine screws, quarter-turn fasteners, or cam-lock mechanisms. The fastener passages 608 may be positioned at corners of the horizontal platen 606, along edges of the horizontal platen 606, or in a rectangular pattern that distributes mounting loads across the horizontal platen 606. The fastener passages 608 may include retention features such as shoulders, snap rings, or captured threads that retain captive fasteners within the fastener passages 608 when the fasteners are in an unfastened state. Alternative fastener passage configurations may include elongated slots that accommodate positional adjustment, keyhole slots that allow quick installation, or threaded inserts that receive externally threaded fasteners.

[0074] A leveling foot 610 is positioned at the base 604 of the equipment handling module 600 and includes a spring 612 that provides a spring-loaded support mechanism. The spring 612 may enable the leveling foot 610 to self-level and support at least a portion of a weight of the equipment handling module 600. The spring-loaded configuration of the leveling foot 610 may allow the leveling foot 610 to automatically adjust to variations in supporting surface height without requiring manual adjustment by a user. The spring 612 may be configured to provide sufficient force to support the weight of the equipment handling module 600 while preventing excessive torque on a mounting connection between the equipment handling module 600 and the liquid handling system. The leveling foot 610 may include a contact pad, a foot pad, or a base plate that contacts the supporting surface and distributes the load from the leveling foot 610 across the supporting surface. The leveling foot 610 may be formed from stainless steel, carbon steel, aluminum, brass, or a rigid polymer material.

[0075] The spring 612 may be selected based on a spring constant of the spring 612, an associated weight of the equipment handling module 600, and a number of springs included in the spring-loaded leveling foot 610. The spring constant may be calculated based on the weight of the equipment handling module 600, the distance from the mounting interface to the leveling foot 610,Docket No. 0083-0034PCT4and the expected range of supporting surface heights. The spring constant may be selected such that the spring 612 provides a spring force that substantially offsets the weight of the equipment handling module 600 when the leveling foot 610 is in contact with a supporting surface. The associated weight of the equipment handling module 600 may include the weight of the vertical cabinet 602, the base 604, the horizontal platen 606, internal mechanical components, and stored labware. The number of springs included in the spring-loaded leveling foot 610 may be selected based on the total spring force required and the available space within the leveling foot 610.

[0076] As further shown in FIG. 6, the spring 612 may comprise a plurality of springs configured to provide the desired spring force and travel characteristics. The plurality of springs may include two springs, three springs, four springs, or more springs arranged in parallel, in series, or in a combination of parallel and series configurations. The plurality of springs may comprise coil springs, which may include compression coil springs, extension coil springs, or conical coil springs that provide variable spring rates. The plurality of springs may alternatively comprise leaf springs, which may include single leaf springs, multi-leaf spring packs, or cantilever leaf springs that provide progressive spring rates. The plurality of springs may comprise torsion springs, which may include helical torsion springs or torsion bars that convert rotational deflection to linear force. The plurality of springs may comprise gas springs, which may include nitrogen gas springs, air springs, or pneumatic cylinders that provide adjustable spring rates and damping characteristics.

[0077] Alternative spring configurations may include belleville washer stacks, wave springs, volute springs, or elastomeric elements such as rubber bushings, silicone pads, or polyurethane bumpers. The spring 612 may be formed from spring steel, stainless steel, music wire, chrome vanadium steel, or other materials that provide fatigue resistance and consistent spring characteristics over extended use. The spring constant of the spring 612 may be selected such that the spring operates within a linear region of the spring force curve across the expected range of compression distances. The spring 612 may include preload adjustment features, travel limiters, or damping elements that provide additional control over the support characteristics of the leveling foot 610. The selection of spring type, spring constant, and number of springs may be based on the operational requirements of the equipment handling module 600, the environmental conditions in which the equipment operates, and the expected range of supporting surface heights at different installation locations.Docket No. 0083-0034PCT4

[0078] Referring to FIG. 7, an equipment handling module 700 is shown in a section view illustrating internal structure and mounting components according to at least one embodiment. The equipment handling module 700 includes a vertical cabinet 702 that extends upward and may be configured to store labware such as tip racks, PCR plates, deep well plates, reagent reservoirs, and other equipment. The vertical cabinet 702 may be formed from sheet metal panels, extruded aluminum framing, cast aluminum components, or a combination of metal and polymer materials that provide structural support and environmental protection for stored labware. The vertical cabinet 702 may include a door, a viewing window, or access panels that allow a user to load labware into the vertical cabinet 702 and visually observe the level of labware within the vertical cabinet 702. The vertical cabinet 702 may include internal support arms, latches, notches, or shelving features for supporting labware within the cabinet during storage and dispensing operations. The vertical cabinet 702 may house a Z-axis component that supports and raises or lowers a stack of labware within the vertical cabinet 702 to isolate a single piece of labware at the bottom of the stack for insertion into an enclosure of a liquid handling system.

[0079] The vertical cabinet 702 connects to a transfer module 704 positioned at a lower portion of the equipment handling module 700. The transfer module 704 may house mechanical components for transitioning labware from vertical movement within the vertical cabinet 702 to horizontal movement into an enclosure of the liquid handling system. The transfer module 704 may include carriages, rails, guides, motors, actuators, lead screws, ball screws, belt drives, or linkage mechanisms for moving labware between vertical and horizontal orientations. The transfer module 704 may be formed from sheet metal, extruded aluminum, machined plate, or a combination of metal and polymer materials that provide structural rigidity and smooth motion characteristics. The transfer module 704 may include mounting features, brackets, or reinforcement structures that support internal components and provide attachment points for external components. Alternative transfer module configurations may include pneumatic actuator systems, rack and pinion systems, or cam-driven mechanisms for transitioning labware between vertical and horizontal movement.

[0080] A horizontal platen 706 extends outward from the transfer module 704 and provides a surface for transporting labware into and out of an enclosure of a liquid handling system. The horizontal platen 706 may be configured to be mounted to a platform of the liquid handling system such that the equipment handling module 700 is cantilevered from the platform. The horizontalDocket No. 0083-0034PCT4platen 706 may pass through an access opening in a housing of the liquid handling system to enable delivery of labware without requiring position calibration. The horizontal platen 706 may be formed from aluminum plate, stainless steel sheet, titanium plate, or a rigid polymer material such as acetal, polycarbonate, or glass-filled nylon. The horizontal platen 706 may include rails, guides, tracks, orbearing surfaces that support and guide an x-axis carriage during horizontal movement. The horizontal platen 706 may include mounting holes, threaded inserts, slots, or fastener passages for receiving fasteners that secure the equipment handling module 700 to a deck of the liquid handling system.

[0081] With continued reference to FIG. 7, an x-axis carriage 708 is positioned along the horizontal platen 706 and may be configured to carry labware horizontally during transfer operations between the equipment handling module 700 and an interior workspace of the liquid handling system. The x-axis carriage 708 may travel along rails, guides, or tracks mounted to the horizontal platen 706. The x-axis carriage 708 may be driven by a lead screw, ball screw, belt drive, rack and pinion, linear motor, or pneumatic actuator. The x-axis carriage 708 may include a platform, tray, or support surface for receiving labware from a Z-axis component within the vertical cabinet 702. The x-axis carriage 708 may be formed from aluminum, stainless steel, brass, or a rigid polymer material such as acetal or glass-filled nylon. The x-axis carriage 708 may include features for engaging with labware such as locating pins, retention clips, magnetic elements, vacuum ports, or friction pads. Alternative carriage configurations may include multiple carriages operating on parallel tracks, a single carriage with multiple labware positions, a carriage with adjustable width to accommodate different labware sizes, or a carriage with pivoting or tilting capability.

[0082] The equipment handling module 700 includes a leveling foot 710 positioned beneath the transfer module 704 to support a weight of the equipment handling module 700. The leveling foot 710 may be positioned beneath the vertical cabinet 702 at a location spaced from a mounting interface formed by the horizontal platen 706. The spacing between the leveling foot 710 and the horizontal platen 706 may distribute the weight of the equipment handling module 700 across multiple support points to reduce mechanical stress on the mounting connection. The leveling foot 710 may include a spring-loaded mechanism that enables self-leveling of the equipment handling module 700 without requiring manual adjustment by a user. The leveling foot 710 may be configured to contact a supporting surface and may be configured to bear a portion of the weightDocket No. 0083-0034PCT4of the equipment handling module 700 when the horizontal platen 706 is mounted to the platform of the liquid handling system. The leveling foot 710 may include a contact pad, a foot pad, or a base plate that contacts the supporting surface and distributes the load from the leveling foot 710 across the supporting surface.

[0083] A spring 712 is associated with the leveling foot 710 and provides a spring-loaded mechanism that enables self-leveling of the equipment handling module 700 without requiring manual adjustment by a user. The spring 712 may comprise a coil spring, a gas spring, abelleville washer stack, a leaf spring, a torsion spring, or an elastomeric element such as a rubber bushing or a silicone pad. The spring 712 may be selected based on a spring constant of the spring 712, an associated weight of the equipment handling module 700, and a number of springs included in the leveling foot 710. The spring 712 may be configured to provide a spring force that substantially offsets the weight of the equipment handling module 700 such that the equipment handling module 700 applies approximately zero net weight to the mounting interface. The spring-loaded configuration of the leveling foot 710 with the spring 712 allows the equipment handling module 700 to accommodate variations in table or supporting surface heights while supporting a portion of the weight of the module, reducing the load transferred to the liquid handling system through the mounting connection. The spring 712 may be formed from spring steel, stainless steel, music wire, chrome vanadium steel, or other materials that provide fatigue resistance and consistent spring characteristics over extended use.

[0084] As further shown in FIG. 7, an internal support beam 714 is visible within the transfer module 704 and provides structural support for the equipment handling module 700. The internal support beam 714 may extend between walls, panels, or frame members of the transfer module 704 to provide rigidity and prevent deflection under load. The internal support beam 714 may be formed from extruded aluminum, steel channel, steel tube, machined plate, or a rigid composite material. The internal support beam 714 may include mounting features, brackets, or attachment points for supporting internal components such as motors, actuators, sensors, or control electronics. Alternative internal support structures may include cross braces, gusset plates, reinforcement ribs, box beam assemblies, or truss structures that provide structural rigidity while minimizing weight. The internal support beam 714 may be positioned to support the horizontal platen 706, the x-axis carriage 708, or drive components associated with the x-axis carriage 708. The internal support beam 714 may include openings, cutouts, or passages that allow routing ofDocket No. 0083-0034PCT4cables, wiring harnesses, or pneumatic tubing between components within the equipment handling module 700.

[0085] Referring to FIG. 8, an equipment handling module 800 is shown in a section view mounted to an enclosure 802 of a liquid handling system. The equipment handling module 800 may be configured to provide labware into the enclosure 802 during processing of samples by the liquid handling system. The enclosure 802 may house robotic components, pipettes, moveable stages, gantry systems, gripper arms, or other elements for aspirating, dispensing, and manipulating liquids and labware within an enclosed workspace. The enclosure 802 may be formed from sheet metal panels, extruded aluminum framing, transparent polymer panels, or a combination of materials that provide structural support and environmental isolation. The equipment handling module 800 may include a vertical cabinet for storing stacks of labware such as tip racks, PCR plates, deep well plates, reagent reservoirs, and other equipment. The equipment handling module 800 may be mounted to the enclosure 802 such that the equipment handling module 800 is cantilevered from a platform or deck of the liquid handling system.

[0086] A horizontal platen 804 extends from the equipment handling module 800 toward the enclosure 802 and may be configured to transport labware between the equipment handling module 800 and an interior of the enclosure 802. The horizontal platen 804 may pass through an access opening in the enclosure 802 to enable delivery of labware without requiring position calibration of the equipment handling module 800 relative to the liquid handling system. The horizontal platen 804 may be formed from aluminum plate, stainless steel sheet, titanium plate, or a rigid polymer material such as acetal, polycarbonate, or glass-filled nylon. The horizontal platen 804 may include rails, guides, tracks, or bearing surfaces that support and guide moving components during horizontal movement. The horizontal platen 804 may include mounting holes, threaded inserts, slots, or fastener passages for receiving fasteners that secure the equipment handling module 800 to a deck of the liquid handling system. The horizontal platen 804 may include captive fasteners configured to protrude from a surface of the horizontal platen 804 when in an unfastened state and to compress flush with the surface when secured to the deck.

[0087] An x-axis carriage 806 is positioned on the horizontal platen 804 and may be configured to transport labware between the equipment handling module 800 and the interior of the enclosure 802. The x-axis carriage 806 may travel along rails, guides, or tracks mounted to the horizontal platen 804. The x-axis carriage 806 may be driven by a lead screw, ball screw, beltDocket No. 0083-0034PCT4drive, rack and pinion, linear motor, or pneumatic actuator. The x-axis carriage 806 may include a platform, tray, or support surface for receiving labware from a Z-axis component within the equipment handling module 800. The x-axis carriage 806 may be formed from aluminum, stainless steel, brass, or a rigid polymer material such as acetal or glass-filled nylon. The x-axis carriage 806 may include features for engaging with labware such as locating pins, retention clips, magnetic elements, vacuum ports, or friction pads. Alternative carriage configurations may include multiple carriages operating on parallel tracks, a single carriage with multiple labware positions, or a carriage with adjustable width to accommodate different labware sizes.

[0088] With continued reference to FIG. 8, an internal support structure 808 provides structural support within the equipment handling module 800. The internal support structure 808 may extend between walls, panels, or frame members of the equipment handling module 800 to provide rigidity and prevent deflection under load. The internal support structure 808 may be formed from extruded aluminum, steel channel, steel tube, machined plate, or a rigid composite material. The internal support structure 808 may include mounting features, brackets, or attachment points for supporting internal components such as motors, actuators, sensors, or control electronics. The internal support structure 808 may be positioned to support the horizontal platen 804, the x-axis carriage 806, or drive components associated with the x-axis carriage 806. Alternative internal support structures may include cross braces, gusset plates, reinforcement ribs, box beam assemblies, or truss structures that provide structural rigidity while minimizing weight.

[0089] A leveling foot 810 is positioned beneath the equipment handling module 800 and includes a spring 812. The leveling foot 810 may be positioned beneath a vertical cabinet of the equipment handling module 800 at a location spaced from a mounting interface formed by the horizontal platen 804. The spring 812 of the leveling foot 810 provides a spring-loaded support mechanism that helps bear a portion of a weight of the equipment handling module 800. The spring-loaded configuration of the leveling foot 810 enables self-leveling without requiring manual adjustment by a user, accommodating variations in supporting surfaces or adjustments made to the liquid handling system. The leveling foot 810 with the spring 812 helps distribute the weight of the equipment handling module 800 so that the full weight is not cantilevered from the mounting connection to the enclosure 802. The leveling foot 810 may include a contact pad, a foot pad, or a base plate that contacts a supporting surface and distributes the load from the leveling foot 810 across the supporting surface.Docket No. 0083-0034PCT4

[0090] The spring 812 may be selected based on a weight of the equipment handling module 800 such that the spring 812 supports a portion of the weight of the equipment handling module 800 to reduce a torque applied to a robot platen or platform by the cantilevered equipment handling module 800. The spring 812 may comprise a coil spring, a gas spring, a belleville washer stack, a leaf spring, a torsion spring, or an elastomeric element such as a rubber bushing or a silicone pad. The spring 812 may be configured to provide a spring force that substantially offsets the weight of the equipment handling module 800 such that the equipment handling module 800 applies approximately zero net weight to a mounting interface. The spring force may be calculated such that the spring force essentially offsets the entire weight of the equipment handling module 800 to prevent the equipment handling module 800 from hanging off a side of the robot platform. The spring force calculation may include additional spring force beyond the calculated weight to provide extra support margin for the equipment handling module 800. The additional spring force may account for manufacturing tolerances, spring relaxation over time, and variations in the weight of the equipment handling module 800 due to component tolerances or stored labware.

[0091] As further shown in FIG. 8, the spring 812 may be selected based on a spring constant of the spring 812, an associated weight of the equipment handling module 800, and a number of springs included in the leveling foot 810. The spring constant may be calculated based on the weight of the equipment handling module 800, the distance from the mounting interface to the leveling foot 810, and the expected range of supporting surface heights. The spring 812 may provide a spring force that substantially offsets the weight of the equipment handling module 800 to reduce a torque applied to the platform by the equipment handling module 800 when cantilevered from the platform. The spring force may be selected such that the equipment handling module 800 is effectively suspended between the mounting interface and the leveling foot 810, with the spring force balancing the weight of the equipment handling module 800. The spring 812 may be formed from spring steel, stainless steel, music wire, chrome vanadium steel, or other materials that provide fatigue resistance and consistent spring characteristics over extended use. The spring 812 may include preload adjustment features, travel limiters, or damping elements that provide additional control over the support characteristics of the leveling foot 810.

[0092] Alternative mounting arrangements may include mounting the equipment handling module 800 to different surfaces of the enclosure 802, such as a side wall, a rear wall, or a top surface of the enclosure 802. The mounting interface may comprise a flanged mounting plate, aDocket No. 0083-0034PCT4bracket assembly, or an adapter plate that accommodates different enclosure configurations or access opening sizes. Alternative enclosure configurations may include enclosures with different numbers of access openings, different access opening positions, or different access opening sizes to accommodate various equipment handling module arrangements. The enclosure 802 may include a single access opening on one side, multiple access openings on one side, or access openings on multiple sides to accommodate one, two, three, four, or more equipment handling modules. The enclosure 802 may include sealing features such as gaskets, brush seals, or overlapping flanges that maintain environmental isolation when the equipment handling module 800 is installed. Alternative leveling foot configurations may include multiple leveling feet positioned at different locations beneath the equipment handling module 800, leveling feet with adjustable preload, or leveling feet with locking mechanisms that secure the leveling foot at a desired height after installation.

[0093] A number of implementations have been described. Nevertheless, it will be understood that various modifications may be made without departing from the spirit and scope of the disclosure. Accordingly, other implementations are within the scope of the following claims.EXAMPLE CLAUSES

[0094] A. A mounting structure for securing a module to a robot platen of a liquid handling system, comprising: a mounting interface configured to attach the equipment handling module to a surface of the robot platen such that the module is cantilevered off an edge of the robot platen; and a spring-loaded leveling foot coupled to the module and configured to contact a supporting surface beneath the equipment handling module, the spring-loaded leveling foot including at least one spring configured to support at least a portion of a weight of the module.

[0095] B The mounting structure of paragraph A, wherein the mounting interface comprises a plurality of spring-loaded captive fasteners configured to protrude from a surface of the mounting portion of the module when in an unfastened state and to compress flush with the surface when secured to the robot platen, the compression of the spring-loaded captive fasteners providing a visual indication of proper installation.

[0096] C. The mounting structure of paragraph B, wherein the spring-loaded captive fasteners are configured to engage with threaded holes in the robot platen.

[0097] D. The mounting structure of any of paragraphs A-C, wherein the at least one spring of the spring-loaded leveling foot is selected based on a weight of the equipment handling moduleDocket No. G083-0034PCT4such that the at least one spring supports a portion of the weight of the equipment handling module to reduce a torque applied to the robot platen by the cantilevered equipment handling module.

[0098] E. The mounting structure of paragraph D, wherein the at least one spring is configured to provide a spring force that substantially offsets the weight of the module such that the module applies approximately zero net weight to the mounting interface.

[0099] F. The mounting structure of any of paragraphs A-E, wherein the at least one spring is selected based on: a spring constant of the at least one spring; an associated weight of the module; and a number of springs included in the spring-loaded leveling foot.

[0100] G. The mounting structure of paragraph F, wherein the at least one spring comprises a plurality of springs.

[0101] H. The mounting structure of any of paragraphs A-G, wherein the at least one spring is selected based on a distance of travel of the spring-loaded leveling foot being at least equal to an adjustable travel height of adjustable feet of the liquid handling system.

[0102] I. The mounting structure of any of paragraphs A-H, wherein the spring-loaded leveling foot is configured to self-level without manual adjustment by a user.

[0103] J. The mounting structure of paragraph I, wherein the spring-loaded leveling foot is positioned beneath a vertical cabinet of the module at a location spaced from the mounting interface.

[0104] K. The mounting structure of any of paragraphs A-J, wherein the module comprises a horizontal platen extending from the mounting interface and configured to pass through an opening in an enclosure of the liquid handling system, the horizontal platen supporting an x-axis carriage for transporting labware into the enclosure.

[0105] L. The mounting structure of any of paragraphs A-K, wherein the mounting interface comprises a platen configured to attach within a deck slot of the robot platen, the platen including a calibration feature configured to engage a calibration slot positioned within the deck slot, the calibration feature enabling a robot of the liquid handling system to utilize the deck slot when the equipment handling module is installed.

[0106] M. The mounting structure of any of paragraphs A-L, wherein the equipment handling module is configured to be installed through an access opening in an enclosure of the liquid handling system, the access opening being accessible upon removal of a side panel from the enclosure.Docket No. 0083-0034PCT4

[0107] N. A module support structure for a module configured to interface with a liquid handling system, comprising: a horizontal platen extending from the module and configured to attach to a deck of the liquid handling system such that the module is cantilevered from the deck; a leveling foot disposed beneath the module and spaced from the horizontal platen, the leveling foot including a spring mechanism configured to automatically adjust to variations in a height of a supporting surface; and at least one fastener configured to secure the horizontal platen to the deck of the liquid handling system.

[0108] O. The module support structure of paragraph N, wherein the at least one fastener comprises a spring-loaded captive fastener configured to protrude from a surface of the horizontal platen when in an unfastened state and to compress flush with the surface when secured to the deck, the compression providing a visual indication of proper installation.

[0109] P. The module support structure of paragraph O, wherein the spring-loaded captive fastener is configured to remain coupled to the horizontal platen when in the unfastened state such that the spring-loaded captive fastener cannot be lost during installation.

[0110] Q. The module support structure of any of paragraphs N-P, wherein the spring mechanism of the leveling foot comprises at least one spring selected based on a weight of the module such that the at least one spring supports a portion of the weight of the module to reduce a load transferred to the deck through the horizontal platen.[0U1] R. The module support structure of any of paragraphs N-Q, wherein the leveling foot is positioned beneath a vertical cabinet of the module, the vertical cabinet configured to store a stack of labware for delivery into an enclosure of the liquid handling system.

[0112] S. The module support structure of any of paragraphs N-R, wherein the horizontal platen is configured to attach within a deck slot of the deck, the horizontal platen including a calibration feature configured to engage a calibration slot positioned within the deck slot, the calibration feature enabling a robot of the liquid handling system to continue utilizing the deck slot when the horizontal platen is installed.

[0113] T. The module support structure of any of paragraphs N-S, wherein the equipment handling module is configured to be installed through an access opening in an enclosure of the liquid handling system, the access opening being defined by a removable side panel of the enclosure.Docket No. 0083-0034PCT4

[0114] U. A module for a liquid handling system, comprising: a vertical cabinet; a transfer platen extending from the vertical cabinet and configured to be mounted to a platform of the liquid handling system; and a spring-loaded foot positioned to contact a supporting surface and configured to bear a portion of a weight of the module when the transfer platen is mounted to the platform.

[0115] V. The module of paragraph U, wherein the spring-loaded foot comprises at least one spring selected based on a weight of the module such that the at least one spring provides a spring force that substantially offsets the weight of the module to reduce a torque applied to the platform by the module when cantilevered from the platform.

[0116] W. The module of paragraph V, wherein the transfer platen includes a plurality of captive fasteners configured to secure the transfer platen to the platform, the captive fasteners configured to protrude from a surface of the transfer platen when in an unfastened state and to compress flush with the surface when secured to the platform.

[0117] X. The module of any of paragraphs U-W, wherein the spring-loaded foot is positioned beneath the vertical cabinet at a location spaced from the transfer platen, the spring-loaded foot configured to self-level without manual adjustment by a user to accommodate variations in a height of the supporting surface.

[0118] Y. The equipment handling module of any of paragraphs U-X, wherein the transfer platen is configured to attach within a deck slot of the platform, the transfer platen including a calibration feature configured to engage a calibration slot positioned within the deck slot, the calibration feature facilitating proper installation of the equipment handling module and enabling a robot of the liquid handling system to utilize the deck slot.

[0119] Z. The equipment handling module of any of paragraphs U-Y, wherein the equipment handling module is configured to be installed through an access opening in an enclosure of the liquid handling system upon removal of a side panel associated with the access opening.

Claims

Docket No. 0083-0034PCT4CLAIMS1. A mounting structure for securing a module to a robot platen of a liquid handling system, comprising:a mounting interface configured to attach the equipment handling module to a surface of the robot platen such that the module is cantilevered off an edge of the robot platen; anda spring-loaded leveling foot coupled to the module and configured to contact a supporting surface beneath the equipment handling module, the spring-loaded leveling foot including at least one spring configured to support at least a portion of a weight of the module.

2. The mounting structure of claim 1, wherein the mounting interface comprises a plurality of spring-loaded captive fasteners configured to protrude from a surface of the mounting portion of the module when in an unfastened state and to compress flush with the surface when secured to the robot platen, the compression of the spring-loaded captive fasteners providing a visual indication of proper installation.

3. The mounting structure of claim 2, wherein the spring-loaded captive fasteners are configured to engage with threaded holes in the robot platen.

4. The mounting structure of claim 1, wherein the at least one spring of the spring-loaded leveling foot is selected based on a weight of the equipment handling module such that the at least one spring supports a portion of the weight of the equipment handling module to reduce a torque applied to the robot platen by the cantilevered equipment handling module.

5. The mounting structure of claim 4, wherein the at least one spring is configured to provide a spring force that substantially offsets the weight of the module such that the module applies approximately zero net weight to the mounting interface.

6. The mounting structure of claim 1, wherein the at least one spring is selected based on:a spring constant of the at least one spring;an associated weight of the module; anda number of springs included in the spring-loaded leveling foot.

7. The mounting structure of claim 6, wherein the at least one spring comprises a plurality of springs.Docket No. 0083-0034PCT48. The mounting structure of claim 1 , wherein the at least one spring is selected based on a distance of travel of the spring-loaded leveling foot being at least equal to an adjustable travel height of adjustable feet of the liquid handling system.

9. The mounting structure of claim 1, wherein the spring-loaded leveling foot is configured to self-level without manual adjustment by a user.

10. The mounting structure of claim 9, wherein the spring-loaded leveling foot is positioned beneath a vertical cabinet of the module at a location spaced from the mounting interface.

11. The mounting structure of claim 1, wherein the module comprises a horizontal platen extending from the mounting interface and configured to pass through an opening in an enclosure of the liquid handling system, the horizontal platen supporting an x-axis carriage for transporting labware into the enclosure.

12. The mounting structure of claim 1, wherein the mounting interface comprises a platen configured to attach within a deck slot of the robot platen, the platen including a calibration feature configured to engage a calibration slot positioned within the deck slot, the calibration feature enabling a robot of the liquid handling system to utilize the deck slot when the equipment handling module is installed.

13. The mounting structure of claim 1, wherein the equipment handling module is configured to be installed through an access opening in an enclosure of the liquid handling system, the access opening being accessible upon removal of a side panel from the enclosure.

14. A module support structure for a module configured to interface with a liquid handling system, comprising:a horizontal platen extending from the module and configured to attach to a deck of the liquid handling system such that the module is cantilevered from the deck;a leveling foot disposed beneath the module and spaced from the horizontal platen, the leveling foot including a spring mechanism configured to automatically adjust to variations in a height of a supporting surface; andat least one fastener configured to secure the horizontal platen to the deck of the liquid handling system.

15. The module support structure of claim 14, wherein the at least one fastener comprises a spring-loaded captive fastener configured to protrude from a surface of the horizontalDocket No. 0083-0034PCT4platen when in an unfastened state and to compress flush with the surface when secured to the deck, the compression providing a visual indication of proper installation.

16. The module support structure of claim 15, wherein the spring-loaded captive fastener is configured to remain coupled to the horizontal platen when in the unfastened state such that the spring-loaded captive fastener cannot be lost during installation.

17. The module support structure of claim 14, wherein the spring mechanism of the leveling foot comprises at least one spring selected based on a weight of the module such that the at least one spring supports a portion of the weight of the module to reduce a load transferred to the deck through the horizontal platen.

18. The module support structure of claim 14, wherein the leveling foot is positioned beneath a vertical cabinet of the module, the vertical cabinet configured to store a stack of labware for delivery into an enclosure of the liquid handling system.

19. The module support structure of claim 14, wherein the horizontal platen is configured to attach within a deck slot of the deck, the horizontal platen including a calibration feature configured to engage a calibration slot positioned within the deck slot, the calibration feature enabling a robot of the liquid handling system to continue utilizing the deck slot when the horizontal platen is installed.

20. The module support structure of claim 14, wherein the equipment handling module is configured to be installed through an access opening in an enclosure of the liquid handling system, the access opening being defined by a removable side panel of the enclosure.

21. A module for a liquid handling system, comprising:a vertical cabinet;a transfer platen extending from the vertical cabinet and configured to be mounted to a platform of the liquid handling system; anda spring-loaded foot positioned to contact a supporting surface and configured to bear a portion of a weight of the module when the transfer platen is mounted to the platform.

22. The module of claim 21, wherein the spring-loaded foot comprises at least one spring selected based on a weight of the module such that the at least one spring provides a spring force that substantially offsets the weight of the module to reduce a torque applied to the platform by the module when cantilevered from the platform.Docket No. 0083-0034PCT423. The module of claim 22, wherein the transfer platen includes a plurality of captive fasteners configured to secure the transfer platen to the platform, the captive fasteners configured to protrude from a surface of the transfer platen when in an unfastened state and to compress flush with the surface when secured to the platform.

24. The module of claim 21, wherein the spring-loaded foot is positioned beneath the vertical cabinet at a location spaced from the transfer platen, the spring-loaded foot configured to self-level without manual adjustment by a user to accommodate variations in a height of the supporting surface.

25. The equipment handling module of claim 21, wherein the transfer platen is configured to attach within a deck slot of the platform, the transfer platen including a calibration feature configured to engage a calibration slot positioned within the deck slot, the calibration feature facilitating proper installation of the equipment handling module and enabling a robot of the liquid handling system to utilize the deck slot.

26. The equipment handling module of claim 21, wherein the equipment handling module is configured to be installed through an access opening in an enclosure of the liquid handling system upon removal of a side panel associated with the access opening.

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