Pulsed field ablation apparatus for treating tissues in organ and method for using same

Abstract

The present invention relates to the technical field of electromagnetic field medical devices. Disclosed are a pulsed field ablation apparatus for treating tissues in an organ and a method for using same. The pulsed field ablation apparatus comprises an electric pulse generator. The electric pulse generator is connected to a control handle by means of an electric wire. The control handle is further connected to an ablation catheter for extending into human tissues. The ablation catheter comprises a limiting shaft rod connected to a front end on the inner side of a sleeve. In the present invention, electrodes protrude outward; the control handle is powered on to form a pulsed electric field, and a resistance block is accordingly powered on and generates heat; the heat is transferred to a limiting block by means of a heat conduction block, and the limiting block expands due to the heat, resulting in an increase in volume, which causes the limiting block to be stuck in a limiting groove; after the limiting block is stuck in the limiting groove, the position of a sliding sleeve is fixed to prevent the sliding sleeve from excessively sliding, thereby protecting a telescopic structure of the control handle. The present invention achieves the beneficial effect of preventing a limiting part from damaging the telescopic structure of the control handle while ensuring that the electrodes of the ablation catheter reset automatically.

Description

A pulsed electric field ablation device for treating tissues in organs and its usage method Technical Field

[0001] This invention relates to the field of electromagnetic field medical equipment technology, specifically to a pulsed electric field ablation device and its usage method for treating tissues in organs. Background Technology

[0002] The pulsed electric field ablation device uses a high-voltage pulsed electric field to destroy the cell membrane, causing irreversible perforation, disrupting cell homeostasis, and ultimately leading to cell death. Compared with thermal ablation technology, its ablation boundary is clear, which can effectively avoid damage to important blood vessels, bile ducts and nerves, and has achieved significant clinical results.

[0003] Prior art CN101309651B discloses apparatus, systems, and methods for mapping electrical signals and ablating tissue. Embodiments include an ablation catheter having ablation elements connected to a deployable set of carrier assemblies. The carrier assemblies can be converted from a compact linear configuration to a helical configuration to map and ablate pulmonary veins.

[0004] Currently, the curvature of the electrode is adjusted by pulling multiple sleeved shafts, and springs are used to restore the deformed electrode. However, the power source for pulling the shafts is still the control handle, which relies on a motor. In particular, when the shafts are retracted and the electrode protrudes, the handle needs to counteract the spring force. This causes the motor in the handle to be pushed back, which can cause the motor drive to fail after a long period of use, resulting in problems with the control of the handle. Technical issues

[0005] To address the shortcomings of existing technologies, this invention provides a pulsed electric field ablation device and method for treating tissues in organs. It has advantages such as ensuring automatic repositioning of the ablation catheter electrodes while limiting the extension structure of the control handle to prevent damage, and synchronizing the electrode usage time with the electrode usage time to prevent failure due to prolonged use. This solves the problems of the aforementioned technologies. Technical solutions

[0006] To achieve the above objectives, the present invention provides the following technical solution: a pulsed electric field ablation device for treating tissues in organs, comprising an electric pulse generator, wherein the electric pulse generator is connected to a control handle via a wire, the control handle is also connected to an ablation catheter for inserting into human tissue, and the ablation catheter and the control handle are connected by a sleeve made of soft material.

[0007] The ablation catheter includes a limiting shaft connected to the front end of the inner side of the cannula. A sliding sleeve is slidably connected to the outer surface of the limiting shaft. The rear end of the sliding sleeve is connected to the front end of the inner side of the cannula via a spring. A limiting groove is formed on the inner side of the limiting shaft. A through hole is formed on the inner side of the limiting shaft. A retraction shaft is provided on the inner side of the through hole, which is parallel to the limiting shaft and located at the axis of the limiting shaft. The retraction shaft and the limiting shaft are connected together to an end. Multiple electrodes are connected between the end and the sliding sleeve. The electrodes are powered by wires disposed in the gap between the limiting shaft and the retraction shaft.

[0008] The limiting shaft has a limiting block installed on its surface for positioning the sliding sleeve. The limiting block slides in the limiting groove with a gap between them. The bottom of the limiting block is connected to a heat-conducting block, and a resistor block is installed at the bottom of the heat-conducting block. The resistor block is also powered by a wire.

[0009] Preferably, the limiting block is made of copper, and the heat-conducting block is welded to the limiting block. The heat-conducting block is made of silver.

[0010] Preferably, the heat-conducting block passes through the limiting shaft and its height does not exceed the surface of the limiting shaft.

[0011] Preferably, the expansion of the limiting block is calculated as follows:

[0012]

[0013] in: It is the length of the expansion; It is the linear thermal expansion coefficient: ; It represents the temperature change, that is, the difference between the initial temperature and the final temperature;

[0014] The calculation formula is:

[0015] in: It is the final temperature; That is the initial temperature.

[0016] Preferably, the front end of the spring is fixedly connected to the rear wall of the sliding sleeve, and the rear end is fixedly connected to the inner wall of the sleeve.

[0017] Preferably, the inner sleeve of the spring receives the retractable shaft rod, and the inner side of the spring does not contact the retractable shaft rod. When the spring is compressed to 60% of its own stroke, the end of the limiting groove on the inner side of the sliding sleeve contacts the limiting block.

[0018] Preferably, the end is connected to the sliding sleeve via an electrode, and when the end moves backward, it compresses the electrode to push it outward, forming a protrusion for emitting a pulsed electric field.

[0019] Preferably, the electrode power supply wire and the resistor block power supply wire are not the same wire, and both wires are connected to the electrical pulse generator through a sleeve.

[0020] Preferably, the two wires are located at the upper and lower ends of the gap between the limiting shaft and the retracting shaft, respectively, and are separated by the retracting shaft.

[0021] A pulsed electric field ablation device and method for treating tissues in organs, comprising the following steps:

[0022] Step 1, Equipment Preparation Stage: An electric pulse generator is used to generate pulsed electric field signals. The electric pulse generator is connected to the control handle via wires. The control handle is used to operate the ablation catheter. The ablation catheter is connected to the control handle and is used to insert into human tissue. A sleeve made of soft material is used to connect the ablation catheter and the control handle to ensure the flexibility and safety of the equipment.

[0023] Step 2, Ablation Catheter Structure Configuration: In the ablation catheter, a limiting shaft is set at the front end, which is installed inside the cannula. A sliding sleeve is slidably connected to the outer surface of the limiting shaft. The rear end of the sliding sleeve is connected to the front end of the inner side of the cannula by a spring. A limiting groove and a through hole are opened inside the limiting shaft. A contraction shaft parallel to the limiting shaft and located at its axis is set in the through hole. The contraction shaft and the limiting shaft are connected together to the end. Multiple electrodes are connected between the end and the sliding sleeve. The electrodes are powered by wires set in the gap between the limiting shaft and the contraction shaft.

[0024] Step 3, Limiting and Positioning Function: Install a limiting block on the surface of the limiting shaft. The limiting block is used to position the sleeve. Slide the limiting block into the limiting groove to ensure that the gap is ≤1 micrometer. Connect a heat-conducting block to the bottom of the limiting block. Install a resistor block at the bottom of the heat-conducting block. The resistor block is also powered by a wire.

[0025] Step 4, Material Selection and Connection Method: The limiting block is made of copper. The heat-conducting block is welded to the limiting block to ensure heat conduction performance. The heat-conducting block is made of silver and passes through the limiting shaft to ensure that its height does not exceed the surface of the limiting shaft.

[0026] Step 5: Operation of the end and electrode: The end is connected to the sliding sleeve via the electrode. When the end moves backward, it compresses the electrode, causing it to expand outward and form a protruding part for emitting pulsed electric fields.

[0027] Step Six: Wire Arrangement and Power Supply: The power supply wires for the electrodes and the power supply wires for the resistor blocks are not the same. The two wires are located at the upper and lower ends of the gap between the limiting shaft and the retraction shaft, respectively, and are separated by the retraction shaft. The wires are connected to the electric pulse generator through a sleeve to ensure a stable output of the pulse electric field. Beneficial effects

[0028] Compared with the prior art, the present invention provides a pulsed electric field ablation device and method for treating tissues in organs, which has the following beneficial effects:

[0029] 1. This invention uses an outward-protruding electrode to control the handle and generate a pulsed electric field. The resistor block is also energized and heats up. The heat is transferred to the limiting block through the heat-conducting block. The limiting block expands due to the heat, increasing its volume and causing it to lock in the limiting groove. Once the limiting block is locked in the limiting groove, the position of the sliding sleeve is fixed, preventing excessive sliding of the sliding sleeve. This protects the telescopic structure of the control handle and achieves the beneficial effect of ensuring the automatic reset of the ablation catheter electrode while preventing damage to the telescopic structure of the control handle.

[0030] 2. In this invention, after the resistor block is energized and heats up, the heat is transferred to the limiting block through the heat-conducting block. The limiting block expands due to heat, increasing its volume and causing it to lock in the limiting groove. Once the limiting block is locked in the limiting groove, the position of the sliding sleeve is fixed, preventing excessive sliding and thus protecting the telescopic structure of the control handle. When the resistor block is de-energized and stops heating, the limiting block cools and contracts, restoring its volume and no longer locking in the limiting groove. The sliding sleeve automatically resets under the action of the spring, and the electrode returns to its original position under the action of the sliding sleeve, completing the reset process. The invention utilizes the expansion characteristics of metal to fix the electrode. The wear caused by the expansion of metal is less than the wear caused by the control handle, achieving the beneficial effect of synchronizing the electrode's time of use with the electrode's usage time and preventing failure due to prolonged use. Attached Figure Description

[0031] Figure 1 is a schematic diagram of the overall structure of the present invention;

[0032] Figure 2 is a schematic diagram of the ablation catheter structure of the present invention;

[0033] Figure 3 is a schematic cross-sectional view of the ablation catheter structure of the present invention;

[0034] Figure 4 is a front cross-sectional schematic diagram of the limiting shaft structure of the present invention;

[0035] Figure 5 is a front cross-sectional schematic diagram of the sliding sleeve structure of the present invention;

[0036] Figure 6 is an enlarged schematic diagram of the limiting block structure of the present invention.

[0037] The components are: 1. Electrical pulse generator; 2. Control handle; 3. Ablation catheter; 4. Sleeve; 5. Limiting shaft; 501. Sliding sleeve; 5011. Limiting groove; 502. Spring; 503. Through hole; 6. Retracting shaft; 7. End; 8. Electrode; 9. Limiting block; 901. Heat-conducting block; 902. Resistance block. Embodiments of the present invention

[0038] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0039] Please refer to Figures 1-6. A pulsed electric field ablation device for treating tissues in organs includes an electric pulse generator 1. The electric pulse generator 1 is connected to a control handle 2 via a wire. The control handle 2 is also connected to an ablation catheter 3 for inserting into human tissue. The ablation catheter 3 and the control handle 2 are connected by a sleeve 4 made of soft material.

[0040] The ablation catheter 3 includes a limiting shaft 5 connected to the inner front end of the sleeve 4. A sliding sleeve 501 is slidably connected to the outer surface of the limiting shaft 5. The rear end of the sliding sleeve 501 is connected to the inner front end of the sleeve 4 through a spring 502. A limiting groove 5011 is opened on the inner side of the limiting shaft 5. A through hole 503 is opened on the inner side of the limiting shaft 5. A retraction shaft 6 is provided on the inner side of the through hole 503, which is parallel to the limiting shaft 5 and located at the axis of the limiting shaft 5. The retraction shaft 6 and the limiting shaft 5 are connected together to an end 7. Multiple electrodes 8 are connected between the end 7 and the sliding sleeve 501. The electrodes 8 are powered by wires arranged in the gap between the limiting shaft 5 and the retraction shaft 6.

[0041] A limiting block 9 for positioning the sliding sleeve 501 is mounted on the surface of the limiting shaft 5. The limiting block 9 slides in the limiting groove 5011 with a gap between them. The bottom of the limiting block 9 is connected to the heat-conducting block 901, and the bottom of the heat-conducting block 901 is equipped with a resistor block 902, which is also powered by wires.

[0042] Specifically, the limiting block 9 is made of copper, and the heat-conducting block 901 is welded to the limiting block 9. The heat-conducting block 901 is made of silver.

[0043] Specifically, the heat-conducting block 901 passes through the limiting shaft 5 and its height does not exceed the surface of the limiting shaft 5.

[0044] Specifically, the expansion calculation for limit block 9 is as follows:

[0045]

[0046] in: It is the length of the expansion; It is the linear thermal expansion coefficient: ; It represents the temperature change, that is, the difference between the initial temperature and the final temperature;

[0047] The calculation formula is:

[0048] in: It is the final temperature; That is the initial temperature.

[0049] Specifically, the front end of the spring 502 is fixedly connected to the rear wall of the sliding sleeve 501, and the rear end is fixedly connected to the inner wall of the sleeve 4.

[0050] Specifically, the inner sleeve of spring 502 receives the retractable shaft 6, and the inner side of spring 502 does not contact the retractable shaft. When spring 502 is compressed to 60% of its own stroke, the end of the limiting groove 401 on the inner side of the sliding sleeve 501 contacts the limiting block 9.

[0051] Specifically, the end 7 is connected to the sliding sleeve 501 via the electrode 8, and when the end 7 moves backward, it compresses the electrode 8 to push it outward, forming a protrusion for emitting a pulsed electric field.

[0052] Specifically, the power supply wire for electrode 8 and the power supply wire for resistor block 902 are not the same; both wires are connected to the electrical pulse generator 1 through sleeve 4.

[0053] Specifically, the two wires are located at the upper and lower ends of the gap between the limiting shaft 5 and the retracting shaft 6, respectively, and are separated by the retracting shaft 6.

[0054] Furthermore, when end 7 moves backward, it compresses electrode 8, causing it to expand outward and form a protruding portion for emitting pulsed electric fields. When end 7 moves forward, the restoring force of spring 502 pushes sliding sleeve 501 forward, thereby returning electrode 8 to its original position.

[0055] Furthermore, the gap between the limiting block 9 and the limiting groove 5011 is ≤1 micrometer at room temperature, ensuring that the sliding sleeve 501 slides freely and the electrode 8 is in an unopened state. The sliding sleeve 501 is held in its initial position under the action of the spring 502. By activating the control handle 2, the retraction shaft 6 moves backward. Since the retraction shaft 6 and the limiting shaft 5 are connected to the end 7 together, the limiting shaft 5 will also move backward and drive the sliding sleeve 501 to move backward as well. However, the sliding sleeve 501 will compress the spring 502 while moving backward, and will be blocked by the spring when it reaches 60% of the spring 502's retraction stroke, preventing it from moving backward any further. Thus, the sliding sleeve 501 remains stationary while the retraction shaft 6 moves backward. At this time, as the two approach each other, the electrode 8 will protrude outward. By energizing the control handle 2, a pulsed electric field is formed.

[0056] Furthermore, the resistor block 902 is also energized and heats up. The heat is transferred to the limiting block 9 through the heat-conducting block 901. The limiting block 9 expands due to the heat, increasing its volume and causing it to lock into the limiting groove 5011. After the limiting block 9 is locked into the limiting groove 5011, the position of the sliding sleeve 501 is fixed, preventing the sliding sleeve 501 from sliding excessively, thereby protecting the telescopic structure of the control handle. When the resistor block 902 is de-energized and stops heating, the limiting block 9 cools down and shrinks, restoring its volume and no longer locking into the limiting groove 5011. The sliding sleeve 501 automatically resets under the action of the spring 502, and the electrode 8 returns to its original position under the action of the sliding sleeve 501, completing the reset process. Example

[0057] Using this pulsed electric field ablation device, the initial temperature The final temperature of the resistor block after it is energized is 25℃. Given a temperature of 100℃, it is necessary to calculate the expansion length of the limiting block under this temperature change. And verify whether it can reliably lock in the limiting groove, thereby fixing the position of the sliding sleeve.

[0058] Parameter definition

[0059] initial length The initial length of the limit block is 10mm;

[0060] linear thermal expansion coefficient The linear thermal expansion coefficient of copper is ;

[0061] Temperature change From the initial temperature To the final temperature The change in quantity.

[0062] Temperature change calculation

[0063]

[0064] Expansion length calculation

[0065]

[0066] Substitute the known parameters into the formula:

[0067] ;

[0068] Calculation results:

[0069] ;

[0070] Results Analysis

[0071] Expansion length The expansion length of the limiting block is 0.012375 mm;

[0072] Limiting groove gap: The gap between the limiting groove and the limiting block is ≤1 micrometer, i.e., 0.001 mm;

[0073] Since the expansion length of the limiting block is 0.012375 mm, which is greater than the gap of the limiting groove by 0.001 mm, the limiting block will be firmly stuck in the limiting groove after being heated and expanded, effectively fixing the position of the sliding sleeve and preventing the sliding sleeve from sliding excessively, thereby protecting the telescopic structure of the control handle.

[0074] Connect the electric pulse generator 1 to the control handle 2 via a wire, and connect the ablation catheter 3 to the control handle 2 via a sleeve 4 made of soft material. Ensure that the limiting block 9 is installed on the surface of the limiting shaft 5 and slides into the limiting groove 5011. The initial temperature is 25℃. Start the electric pulse generator 1 through the control handle to energize the resistor block 902 and heat it to 100℃. The limiting block 9 expands due to heat, with an expansion length of 0.012375 mm. After expansion, the limiting block 9 is stuck in the limiting groove 5011, and the position of the sliding sleeve 501 is fixed. Move the operating end 7 backward to compress the electrode 8, causing it to expand outward and form a protruding part for emitting a pulse electric field. Disconnect the power supply to the resistor block 902. The limiting block 9 cools and contracts. The sliding sleeve 501 automatically resets under the action of the spring 502. The electrode 8 returns to its original position under the action of the sliding sleeve 501, completing the reset process.

[0075] The thermal expansion mechanism of the limiting block effectively fixes the position of the sliding sleeve, preventing excessive sliding and thus protecting the telescopic structure of the control handle. Simultaneously, the electrodes can automatically reset, ensuring the reliability and safety of the equipment.

[0076] The usage method includes the following steps:

[0077] Step 1, Equipment Preparation Stage: Electric pulse generator 1 is used to generate pulse electric field signals. Electric pulse generator 1 is connected to control handle 2 through wires. Control handle 2 is used to operate ablation catheter 3. Ablation catheter 3 is connected to control handle 2. Ablation catheter 3 is used to insert into human tissue. A sleeve 4 made of soft material is used to connect ablation catheter 3 and control handle 2 to ensure the flexibility and safety of the equipment.

[0078] Step 2, Ablation Catheter Structure Configuration: In the ablation catheter 3, a limiting shaft 5 is set at the front end. The limiting shaft 5 is installed inside the sleeve 4. A sliding sleeve 501 is slidably connected to the outer surface of the limiting shaft 5. The rear end of the sliding sleeve 501 is connected to the front end of the inner side of the sleeve 4 through a spring 502. A limiting groove 5011 and a through hole 503 are opened inside the limiting shaft 5. A contraction shaft 6 is set in the through hole 503, which is parallel to the limiting shaft 5 and located at its axis. The contraction shaft 6 and the limiting shaft 5 are connected together to the end 7. Multiple electrodes 8 are connected between the end 7 and the sliding sleeve 501. The electrodes 8 are powered by wires set in the gap between the limiting shaft 5 and the contraction shaft 6.

[0079] Step 3, Limiting and Positioning Function: Install a limiting block 9 on the surface of the limiting shaft 5. The limiting block 9 is used to position the sleeve 4. Slide the limiting block 9 into the limiting groove 5011 to ensure that the gap is ≤1 micrometer. The bottom of the limiting block 9 is connected to the heat-conducting block 901. A resistor block 902 is installed at the bottom of the heat-conducting block 901. The resistor block 902 is also powered by wires.

[0080] Step 4, Material Selection and Connection Method: The limiting block 9 is made of copper. The heat-conducting block 901 is welded to the limiting block 9 to ensure heat conduction performance. The heat-conducting block 901 is made of silver and passes through the limiting shaft 5 to ensure that its height does not exceed the surface of the limiting shaft 5.

[0081] Step 5, Operation of the end and electrode: End 7 is connected to sliding sleeve 501 via electrode 8. When end 7 moves backward, it compresses electrode 8, causing it to expand outward and form a protruding portion for emitting pulsed electric fields.

[0082] Step 6, Wire Arrangement and Power Supply: The power supply wire for electrode 8 and the power supply wire for resistor block 902 are not the same. The two wires are located at the upper and lower ends of the gap between the limiting shaft 5 and the retraction shaft 6, respectively, and are separated by the retraction shaft 6. The wires are connected to the electric pulse generator 1 through the sleeve 4 to ensure the stable output of the pulse electric field.

[0083] During use, the gap between the limiting block 9 and the limiting groove 5011 is ≤1 micrometer at room temperature, ensuring that the sliding sleeve 501 slides freely and the electrode 8 is in an unopened state. The sliding sleeve 501 is held in its initial position by the action of the spring 502. By activating the control handle 2, the retraction shaft 6 moves backward. Since the retraction shaft 6 and the limiting shaft 5 are connected to the end 7 together, the limiting shaft 5 will also retract and drive the sliding sleeve 501 to retract as well. However, as the sliding sleeve 501 retracts, it will compress the spring 502, and when it reaches 60% of the spring 502's retraction stroke, it will be blocked by the spring, preventing it from retracting further. Thus, the sliding sleeve 501 remains stationary while the retraction shaft 6 moves backward. At this time, as the two approach each other, the electrode 8 will move backward. Electrode 8 protrudes outward, forming a pulsed electric field when the control handle 2 is energized. Furthermore, resistor 902 is also energized and heats up. The heat is transferred to limiting block 9 via heat-conducting block 901. Limiting block 9 expands due to heat, increasing its volume and causing it to lock into limiting groove 5011. Once locked in limiting groove 5011, the position of sliding sleeve 501 is fixed, preventing excessive sliding and protecting the telescopic structure of the control handle. When resistor 902 is de-energized and stops heating, limiting block 9 cools and contracts, restoring its volume and no longer locking into limiting groove 5011. Sliding sleeve 501 automatically resets under the action of spring 502, and electrode 8 returns to its original position under the action of sliding sleeve 501, completing the reset process.

[0084] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A pulsed electric field ablation device for treating tissues in organs, comprising an electric pulse generator (1), the electric pulse generator (1) being connected to a control handle (2) via a wire, the control handle (2) being further connected to an ablation catheter (3) for insertion into human tissue, characterized in that: The ablation catheter (3) is connected to the control handle (2) by a cannula (4) made of soft material; The ablation catheter (3) includes a limiting shaft (5) connected to the front end of the inner side of the sleeve (4). The outer surface of the limiting shaft (5) is slidably connected to a sliding sleeve (501). The rear end of the sliding sleeve (501) is connected to the front end of the inner side of the sleeve (4) through a spring (502). A limiting groove (5011) is opened on the inner side of the limiting shaft (5). A through hole (503) is opened on the inner side of the limiting shaft (5). A shrinking shaft (6) is provided on the inner side of the through hole (503) that is parallel to the limiting shaft (5) and located at the axis of the limiting shaft (5). The shrinking shaft (6) and the limiting shaft (5) are connected together to an end (7). Multiple electrodes (8) are connected between the end (7) and the sliding sleeve (501). The electrodes (8) are powered by wires arranged in the gap between the limiting shaft (5) and the shrinking shaft (6). The limiting shaft (5) is equipped with a limiting block (9) for positioning the sliding sleeve (501). The limiting block (9) slides in the limiting groove (5011) with a gap between them. The bottom of the limiting block (9) is connected to a heat-conducting block (901). A resistor block (902) is installed at the bottom of the heat-conducting block (901). The resistor block (902) is also powered by a wire.

2. The pulsed electric field ablation device for treating tissues in organs according to claim 1, characterized in that: The limiting block (9) is made of copper, and the heat-conducting block (901) is welded to the limiting block (9). The heat-conducting block (901) is made of silver.

3. The pulsed electric field ablation device and method for treating tissues in organs according to claim 2, characterized in that: The heat-conducting block (901) passes through the limiting shaft (5) and its height does not exceed the surface of the limiting shaft (5).

4. The pulsed electric field ablation device and method for treating tissues in organs according to claim 3, characterized in that: The expansion calculation of the limiting block (9) is as follows: ； in: It is the length of the expansion; It is the linear thermal expansion coefficient: ； It represents the temperature change, that is, the difference between the initial temperature and the final temperature; The calculation formula is: ； in: It is the final temperature; That is the initial temperature.

5. A pulsed electric field ablation device for treating tissues in organs according to claim 4, characterized in that: The front end of the spring (502) is fixedly connected to the rear wall of the sliding sleeve (501), and the rear end is fixedly connected to the inner wall of the sleeve (4).

6. A pulsed electric field ablation device for treating tissues in organs according to claim 5, characterized in that: The inner sleeve of the spring (502) receives the retractable shaft (6), and the inner side of the spring (502) does not contact the retractable shaft. When the spring (502) is compressed to 60% of its own stroke, the end of the limiting groove (401) on the inner side of the sliding sleeve (501) contacts the limiting block (9).

7. A pulsed electric field ablation device for treating tissues in organs according to claim 6, characterized in that: The end (7) is connected to the sliding sleeve (501) via the electrode (8), and when the end (7) moves backward, it compresses the electrode (8) to make it spread outward, forming a protrusion for emitting a pulse electric field.

8. A pulsed electric field ablation device for treating tissues in organs according to claim 7, characterized in that: The power supply wire for electrode (8) and the power supply wire for resistor block (902) are not the same. Both wires are connected to the electrical pulse generator (1) through sleeve (4).

9. A pulsed electric field ablation device for treating tissues in organs according to claim 8, characterized in that: The two wires are located at the upper and lower ends of the gap between the limiting shaft (5) and the retracting shaft (6), and are separated by the retracting shaft (6).

10. A method of using a pulsed electric field ablation device for treating tissues in organs, characterized in that, The method of use is applied to the pulsed electric field ablation device according to claim 1, and the method of use includes the following steps: Step 1, Equipment Preparation Stage: Electric pulse generator (1) is used to generate pulse electric field signals. The electric pulse generator (1) is connected to the control handle (2) through wires. The control handle (2) is used to operate the ablation catheter (3). The ablation catheter (3) is connected to the control handle (2). The ablation catheter (3) is used to insert into human tissue. A sleeve (4) made of soft material is used to connect the ablation catheter (3) and the control handle (2) to ensure the flexibility and safety of the equipment. Step 2, Ablation Catheter Structure Configuration: In the ablation catheter (3), a limiting shaft (5) is set at the front end. The limiting shaft (5) is installed inside the sleeve (4). A sliding sleeve (501) is slidably connected to the outer surface of the limiting shaft (5). The rear end of the sliding sleeve (501) is connected to the front end of the inner side of the sleeve (4) through a spring (502). A limiting groove (5011) and a through hole (503) are opened inside the limiting shaft (5). A contraction shaft (6) is set in the through hole (503) that is parallel to the limiting shaft (5) and located at its axis. The contraction shaft (6) and the limiting shaft (5) are connected together to the end (7). Multiple electrodes (8) are connected between the end (7) and the sliding sleeve (501). The electrodes (8) are powered by wires set in the gap between the limiting shaft (5) and the contraction shaft (6). Step 3, Limiting and Positioning Function: Install a limiting block (9) on the surface of the limiting shaft (5). The limiting block (9) is used to position the sleeve (4). Slide the limiting block (9) into the limiting groove (5011) to ensure that the gap is ≤1 micrometer. Connect the bottom of the limiting block (9) to the heat-conducting block (901). Install the resistor block (902) at the bottom of the heat-conducting block (901). The resistor block (902) is also powered by the wire. Step 4, Material selection and connection method: The material of the limiting block (9) is copper. The heat-conducting block (901) is welded to the limiting block (9) to ensure heat conduction performance. The material of the heat-conducting block (901) is silver and passes through the limiting shaft (5) to ensure that its height does not exceed the surface of the limiting shaft (5). Step 5, Operation of the end and electrode: The end (7) is connected to the sliding sleeve (501) via the electrode (8). When the end (7) moves backward, it compresses the electrode (8) to make it spread outward, forming a protruding part for emitting pulsed electric fields. Step 6, Wire Arrangement and Power Supply: The power supply wires of the electrode (8) and the power supply wires of the resistor block (902) are not the same. The two wires are located at the upper and lower ends of the gap between the limiting shaft (5) and the contraction shaft (6), and are separated by the contraction shaft (6). The wires are connected to the electric pulse generator (1) through the sleeve (4) to ensure the stable output of the pulse electric field.

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