Urine analyzer and control method therefor

Abstract

The present invention relates to a urine analyzer and a control method therefor. The method comprises the steps of: S1: switching a rotary switch valve to a sample flow channel, and drawing a sample in a sample collection chamber into a transfer channel; S2: communicating the transfer channel with a test flow channel, and driving water in a clean water collection chamber to flow into a common flow channel and the transfer channel, so that the water in the transfer channel is mixed with the sample in the transfer channel; S3: switching the rotary switch valve to the test flow channel, and discharging the sample-water mixture in the transfer channel; S4: pumping water in the common flow channel into a test chamber for testing; S5: switching the rotary switch valve to a sample flow channel, and quantitatively drawing the sample into the transfer channel; S6: switching the rotary switch valve to a reagent flow channel, communicating the transfer channel with the reagent flow channel, and quantitatively drawing a reagent in a reagent chamber into the transfer channel; S7: switching the rotary switch valve to the test flow channel, and pumping the reagent and the sample in the transfer channel into the test chamber; S8: a tester starting to perform testing; and S9: pumping the water in the common flow channel into the test flow channel, and discharging the water from the test chamber.

Description

Urine analyzer and its control method

[0001] This invention claims priority to Chinese Patent Application No. 202510361614.0, filed with the Chinese Patent Office on March 26, 2025, entitled “Urine Analyzer and Control Method Thereof,” the entire contents of which are incorporated herein by reference. Technical Field

[0002] This invention relates to the field of urine analyzer technology, and in particular to a urine analyzer and its control method. Background Technology

[0003] With increasing human lifespan, the importance of health care and maintenance has received growing attention. Urine can reflect a person's health status to a certain extent, and quantitative analysis of urine components can reveal diseases of the pancreas and kidneys. Urine analysis is an important indicator for detecting a person's physical condition, typically testing for pH, protein, occult blood, specific gravity, glucose, ketones, urobilinogen, nitrates, white blood cells, bilirubin, and vitamin C, reflecting a range of indicators of the body. Urine tests are usually conducted in hospitals. Due to strained medical resources, patients often have to queue to register, see a doctor, pay fees, collect urine samples, and wait for batches of urine tests before queuing for results, which is time-consuming and laborious.

[0004] Currently, there are home-use urine testing devices on the market that cannot accurately quantify sample and reagent extraction, and they are slow to operate and have a poor user experience. Summary of the Invention

[0005] The purpose of this invention is to provide a urine analyzer and its control method to solve the problems of the prior art.

[0006] To address the aforementioned technical problems, embodiments of the present invention provide a urine analyzer, the urine analyzer comprising:

[0007] A reagent kit, wherein the reagent kit has multiple reagent chambers, and reagents are placed in the reagent chambers;

[0008] The collector is equipped with a sample collection chamber and a water collection chamber;

[0009] A rotary valve is provided with a common flow channel, a sample flow channel, multiple reagent flow channels, a detection flow channel, an air flow channel, and a transfer channel; the sample flow channel is connected to the sample collection chamber via a lower sample pipe; the common flow channel is connected to the water collection chamber; the multiple reagent flow channels are respectively connected to multiple reagent chambers; one end of the transfer channel is connected to the inner end of the common flow channel, and the other end is operably connected to the sample flow channel, the multiple reagent flow channels, the detection flow channel, and the air flow channel;

[0010] The detection mechanism includes a detector and a detection chamber, the detection chamber being connected to the detection flow channel.

[0011] This invention designs a control method for a urine analyzer, using the aforementioned urine analyzer, and includes the following steps:

[0012] S1: The rotary valve switches to the sample flow channel, drawing the sample from the sample collection chamber into the transfer channel;

[0013] S2: The rotary valve switches to the detection channel, the transfer channel is connected to the detection channel, and the water in the clear water collection chamber is driven to flow into the common channel and the transfer channel, and the water in the transfer channel and the sample in the transfer channel are mixed;

[0014] S3: The rotary valve switches to the detection channel to drain the mixed sample and water in the transfer channel;

[0015] S4: Push the water in the common flow channel into the detection chamber for detection;

[0016] S5: The rotary cutting valve switches to the sample flow channel to quantitatively extract the sample into the transfer channel;

[0017] S6: The rotary valve switches to the reagent flow channel, the transfer channel is connected to the reagent flow channel, and the reagent in the reagent chamber is quantitatively drawn into the transfer channel;

[0018] S7: The rotary valve switches to the detection channel, pushing the reagents and samples in the transfer channel into the detection chamber;

[0019] S8: The detector begins detection;

[0020] S9: Push the water in the common flow channel into the detection flow channel and discharge it from the detection chamber.

[0021] In one embodiment, the sample flow channel includes:

[0022] The lower sample flow channel, which is connected to the sample collection chamber via a lower sample conduit and is equipped with a sample burette; and

[0023] Upper sample flow channel, wherein the upper sample flow channel is connected to the sample burette;

[0024] Step S1 includes:

[0025] S1.1: The rotary valve switches to the upper sample flow channel, the transfer channel is connected to the upper sample flow channel, and the air in the upper sample flow channel and the sample burette is extracted, a negative pressure is formed in the sample burette, and the sample in the sample collection chamber flows into the sample burette;

[0026] S1.2: Switch the rotary valve to connect the transfer channel with the lower sample flow channel, and drive the sample in the sample burette to flow into the transfer channel.

[0027] In one embodiment, the urine analyzer further includes:

[0028] A first pump, the first pump being connected to two pipes, one of which is connected to the clean water collection chamber; and

[0029] A second pump is connected to another pipe and a drive pipe, the drive pipe being in communication with the common flow channel;

[0030] In step S1.1, the first pump is started to extract air from the upper sample flow channel and the sample burette;

[0031] In step S1.2, the first pump is started, drawing the sample from the sample burette into the transfer channel;

[0032] In step S2, the first pump is started to pump the water in the clean water collection chamber into the common flow channel and the transfer channel;

[0033] In step S3: the rotary valve switches to the air channel, the transfer channel is connected to the air channel, after the control module controls the second pump to start drawing air, the rotary valve switches to the detection channel, the second pump starts, and the mixed sample and water in the transfer channel are discharged from the detection channel and the detection chamber;

[0034] In step S4, the first pump is started to push the water in the common flow channel into the detection flow channel; then the rotary valve is switched to the air flow channel, the second pump is started and draws a certain amount of air into the transfer channel, the rotary valve is switched to the detection flow channel again, the second pump is started to push the water in the detection flow channel into the detection chamber for detection;

[0035] In step S5, the second pump is started to quantitatively extract the sample into the transfer channel;

[0036] In step S6, the second pump is started and quantitatively draws the reagent from the reagent chamber into the transfer channel;

[0037] In step S7, the second pump is activated and pushes the reagents and samples in the transfer channel into the detection chamber;

[0038] In step S9, the rotary valve switches to the detection channel, the first pump starts and pushes the water in the common channel into the detection channel, and then discharges it from the detection chamber.

[0039] In one embodiment, in step S5, it is first determined whether the sample needs to be diluted.

[0040] If dilution is required, the rotary valve first switches to the detection channel, the first pump starts, and a measured amount of water is pushed into the detection channel; then the rotary valve switches to the air channel, the second pump starts and draws a measured amount of air into the transfer channel; after the rotary valve switches back to the detection channel, the second pump starts and draws the water in the detection channel into the transfer channel; the rotary valve switches to the lower sample channel, the second pump starts, and a measured amount of sample in the lower sample channel is drawn into the transfer channel and mixed with the water in the transfer channel; then the rotary valve switches to the air channel, the second pump starts again and draws a measured amount of air into the transfer channel; the rotary valve switches back to the detection channel, the second pump starts, and the diluted sample is pushed into the transfer channel;

[0041] The second pump starts and draws a quantitative amount of diluted sample from the detection channel into the transfer channel. Then, the rotary valve switches back to the air channel and draws a quantitative amount of air into the transfer channel again. The rotary valve switches back to the detection channel, and the second pump starts and pushes the air drawn in the transfer channel into the detection channel.

[0042] If dilution is not required, the rotary valve switches the air flow channel, first quantitatively drawing in air, and then the rotary valve switches to the lower sample flow channel, at which point the second pump starts and quantitatively draws in the sample into the transfer channel.

[0043] In one embodiment, it is determined whether multiple reagents need to be extracted. If only one reagent needs to be extracted, step S7 is performed after step S6. If multiple reagents need to be extracted, step S6 is repeated multiple times. After each reagent extraction, the rotary valve needs to be switched to the detection channel to push the reagent into the detection channel, and then the rotary valve is switched to a different reagent channel to extract the reagent again.

[0044] In one embodiment, the rotary valve is provided with a mixing chamber, which is located on the path of the detection channel and communicates with the detection channel;

[0045] In step S8, after the rotary valve is switched to the detection channel, the second pump is started, pushing the reagents and samples in the transfer channel into the mixing chamber to mix into a homogenized liquid. Then, the second pump is started again to push the homogenized liquid into the detection chamber.

[0046] In one embodiment, in step S8, the second pump starts for a preset time, then resets the preset time, mixes the reagent and sample in the mixing chamber into the mixed liquid, and then the second pump pushes the mixed liquid into the detection chamber.

[0047] In one embodiment, the mixing cavity includes a mixing bend and at least one mixing chamber that are in communication with each other, wherein the mixing bend is a curved flow channel.

[0048] In step S8, the second pump starts for a preset time and then resets the preset time. After the reagent and sample are continuously mixed into a homogenized liquid by flowing through the mixing bend and the mixing chamber, the second pump resets and pushes the homogenized liquid into the detection chamber.

[0049] In one embodiment, in step S8, the second pump is reset, and after the reagents and samples in the transfer channel are pushed into the mixing chamber to mix into the mixed liquid, the rotary valve is switched to the air channel, the second pump is started and quantitatively draws air into the transfer channel, and then the rotary valve is switched to the detection channel again, and the second pump is reset to push the mixed liquid in the mixing chamber into the detection chamber.

[0050] In one embodiment, in step S9, the first pump starts and pushes the water in the common channel into the detection channel, where it mixes with the sample and reagents in the detection chamber to form waste liquid; the rotary valve switches to the air channel, the second pump starts and draws air into the transfer channel, then the rotary valve switches back to the detection channel, the second pump resets and discharges the waste liquid from the detection chamber.

[0051] In one embodiment, after step S9, step S10 is further included: the first pump is started to push the water in the common flow channel into the detection flow channel and discharge it from the detection chamber;

[0052] Then the rotary valve switches to the lower sample flow channel, the first pump starts, pushing the water in the common flow channel from the lower sample flow channel into the sample collection chamber, and then discharging it from the sample collection chamber; or

[0053] After step S9, step S10 is also included: the rotary valve switches to the lower sample flow channel, the first pump starts, and pushes the water in the common flow channel from the lower sample flow channel into the sample collection chamber and discharges from the sample collection chamber;

[0054] The first pump starts, pushing the water in the common flow channel into the detection flow channel and then discharging it from the detection chamber.

[0055] In one embodiment, after step S10, step S11 is further included: the rotary valve switches to the detection channel, the first pump starts, and pushes all the remaining water in the common channel into the detection channel and discharges it from the detection chamber.

[0056] In one embodiment, a first sensor is provided inside the sample burette;

[0057] The urine analyzer also includes a control module, which is connected to the first pump, the second pump, the rotary valve, and the first sensor.

[0058] Before step S2, the process also includes the following steps: the first sensor sends the sample volume information sensed in the sample burette to the control module. If the sample volume information does not meet the requirements, the process ends; if it meets the requirements, step S2 is executed.

[0059] In step S8, the detector sends the detection result to the control module after detection.

[0060] In one embodiment, after step S9, if the detection result is abnormal, steps S1 to S9 are repeated; if the detection result is normal, the next detection item is performed.

[0061] In one embodiment, the urine analyzer further includes a warning light, which is electrically connected to the control module;

[0062] After step S9, if two consecutive detection results are abnormal, the control module will control the indicator light to issue a warning.

[0063] In one embodiment, a second sensor connected to the control module is provided inside the clean water collection chamber;

[0064] Before step S3, the process includes the following step: the second sensor sends the detected amount of clean water in the clean water collection chamber to the control module. If the amount does not meet the requirements, the control module controls the process to end; if the amount meets the requirements, then step S4 is performed.

[0065] In one embodiment, the rotary valve is further provided with a washing flow channel;

[0066] The urine analyzer also includes a washing solution and a washing chamber for holding the washing solution;

[0067] After steps S1 to S9 have been cycled a preset number of times, the reagent kit needs to be replaced. The process also includes the following steps:

[0068] S01: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the detection channel sequentially from the common channel;

[0069] S02: The rotary valve switches to the air flow channel, the second pump or the first pump starts, and draws air into the transfer channel;

[0070] S03: The rotary valve switches to the washing channel, the second pump starts, and draws a quantitative amount of washing liquid into the transfer channel;

[0071] S04: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the detection channel and mixes it with the water in the detection channel to form a diluted washing liquid. Then the first pump starts and draws the diluted washing liquid in the detection channel into the transfer channel.

[0072] S05: The rotary valve switches to one of the reagent channels, the first pump starts, and pushes the diluted washing solution in the transfer channel into the reagent channel and the reagent chamber; the rotary valve switches multiple reagent channels in sequence, the first pump starts, and pushes the diluted washing solution in the transfer fluid into multiple reagent chambers in sequence;

[0073] S06: The rotary valve switches to multiple reagent channels in sequence, the first pump starts, and pushes the clean water in the common channel into multiple reagent channels and multiple reagent chambers in sequence;

[0074] S07: Replace with a new reagent kit.

[0075] In one embodiment, the rotary valve is provided with a mixing chamber, which is located on the path of the detection channel and communicates with the detection channel;

[0076] Step S01: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the mixing chamber sequentially from the common channel;

[0077] Step S04: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the detection channel and then into the mixing chamber. The first pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid. Then the first pump starts to draw the diluted washing liquid in the detection channel into the transfer channel.

[0078] In one embodiment, the rotary valve is further provided with a washing flow channel;

[0079] The urine analyzer also includes a washing solution and a washing chamber for holding the washing solution;

[0080] After steps S1 to S9 have been cycled a preset number of times, the urine analyzer is periodically cleaned, including the following steps:

[0081] S001: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the detection channel sequentially from the common channel;

[0082] S002: The rotary valve switches to the air flow channel, the second pump or the first pump starts, and draws air into the transfer channel;

[0083] S003: The rotary valve switches to the washing channel, the second pump starts, and draws a quantitative amount of washing liquid into the transfer channel;

[0084] S004: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the detection channel, and mixes it with the water in the detection channel to form a diluted washing liquid;

[0085] S005: The first pump starts and draws the diluted washing solution in the detection channel into the transfer channel;

[0086] S005: The rotary cutting valve switches to the lower sample flow channel, the first pump starts, and pushes the diluent washing solution in the transfer channel into the sample collection chamber;

[0087] S006: Repeat steps S001 to S004, the first pump is started, and the diluted washing liquid in the detection channel is pushed into the detection chamber;

[0088] S007: After a preset time, the rotary valve first switches to the lower sample flow channel, the first pump starts, and pushes the water in the common flow channel into the sample collection chamber and then discharges it. Then, the rotary valve switches to the detection flow channel, the first pump starts, and pushes the water in the common flow channel into the detection chamber and then discharges it; or

[0089] After waiting for a preset time, the rotary valve switches to the detection channel, the first pump starts, and pushes the water in the common channel into the detection chamber and then discharges it. Then, the rotary valve switches to the lower sample channel, the first pump starts, and pushes the water in the common channel into the sample collection chamber and then discharges it.

[0090] In one embodiment, the rotary valve is provided with a mixing chamber, which is located on the path of the detection channel and communicates with the detection channel;

[0091] Step S001: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the mixing chamber sequentially from the common channel;

[0092] Step S004: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the mixing chamber, the first pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid, and then the first pump starts and draws the diluted washing liquid in the detection channel into the transfer channel.

[0093] In one embodiment, the rotary valve includes:

[0094] A microfluidic chip, comprising the common channel, the lower sample channel, the upper sample channel, the water channel, multiple reagent channels, the detection channel, and the air channel; and

[0095] The rotor is rotatably connected to the microfluidic chip and has the transfer channel. The inner end of the transfer channel is connected to the common channel, and the outer end rotates with the rotor and is connected to the lower sample channel, the upper sample channel, the water channel, multiple reagent channels, the detection channel and the air channel.

[0096] In one embodiment, the microfluidic chip includes:

[0097] The flow channel plate has the following features on its front side:

[0098] A central hole, which penetrates the flow channel plate and communicates with the inner end of the common flow channel; and

[0099] Multiple circumferential holes, the multiple circumferential holes being arranged around the central hole; and

[0100] A sealing plate, the sealing plate being stacked between the front side of the flow channel plate and the rear side of the reagent kit;

[0101] The lower sample channel, the upper sample channel, the clear water channel, the plurality of reagent channels, the detection channel, and the air channel are respectively connected to the plurality of circumferential holes.

[0102] In one embodiment, the urine analyzer also includes a housing.

[0103] The outer casing includes a detachable first casing and a second casing;

[0104] The detection mechanism includes a detection plate, and the detection plate is provided with the detection cavity;

[0105] The reagent kit, the microfluidic chip, and the detection plate are located inside the first housing.

[0106] The first pump, the second pump, the rotor, and the detector are located inside the second housing. Attached Figure Description

[0107] Figure 1 is a perspective view of a urine analyzer according to an embodiment of the present invention.

[0108] Figures 2, 3, 4, 5, 6, 7, and 8 are exploded views of the urine analyzer of the embodiment shown in Figure 1.

[0109] Figure 9 is a perspective view of the locking element in the embodiments shown in Figures 1-8.

[0110] Figures 10 and 11 are perspective views of the kit in the embodiment shown in Figure 2.

[0111] Figures 12 and 13 are perspective views of the cover plate in the embodiment shown in Figure 2.

[0112] Figure 14 is a perspective view of the flow channel plate in the embodiment shown in Figure 2.

[0113] Figure 15 is a partial enlarged view of area A of the flow channel plate in Figure 14.

[0114] Figure 16 is a partial enlarged view of region B of the flow channel plate in Figure 14.

[0115] Figure 17 is a perspective view of the flow channel plate in the embodiment shown in Figure 2.

[0116] Figure 18 is a perspective view of the first adapter of the embodiment shown in Figures 4 and 5.

[0117] Figure 19 is an assembly diagram of the reagent kit, flow channel plate, capping plate, first adapter, rotor and protective cover in the embodiment shown in Figures 4 and 5.

[0118] Figure 20 is an exploded view of the first housing in the embodiment shown in Figure 1.

[0119] Figure 21 is a perspective view of the detection plate in the embodiment shown in Figure 2.

[0120] Figures 22 and 23 are exploded views of the protective cover, rotor, compression spring, and convex ring in the embodiment shown in Figure 2.

[0121] Figure 24 is an exploded view of the second housing, peristaltic pump, plunger pump and motor in the embodiment shown in Figure 1.

[0122] Figure 25 is a perspective view of a data collector according to an embodiment of the present invention.

[0123] Figures 26 and 27 are exploded views of the data collector in the embodiment shown in Figure 25.

[0124] Figure 28 is a perspective view of the data collector according to another embodiment of the present invention.

[0125] Figures 29 and 30 are exploded views of the data collector in the embodiment shown in Figure 28.

[0126] Figure 31 is a flowchart of the control method of a urine analyzer according to an embodiment of the present invention.

[0127] Figure 32 is a fluid circuit diagram of a urine analyzer according to an embodiment of the present invention. Detailed Implementation

[0128] To make the objectives, technical solutions, and advantages of this invention clearer, the various embodiments of this invention will be described in detail below with reference to the accompanying drawings. However, those skilled in the art will understand that many technical details have been provided in the various embodiments of this invention to facilitate a better understanding of this application. However, the technical solutions claimed in the claims of this application can be implemented even without these technical details and with various variations and modifications based on the following embodiments.

[0129] Unless the context requires otherwise, throughout the specification and claims, the word “comprising” and its variations, such as “including” and “having”, shall be understood to have an open, inclusive meaning, that is, to be interpreted as “including, but not limited to”.

[0130] The embodiments of the present invention will be described in detail below with reference to the accompanying drawings to provide a clearer understanding of the purpose, features, and advantages of the present invention. It should be understood that the embodiments shown in the drawings are not intended to limit the scope of the present invention, but are merely illustrative of the essential spirit of the technical solution of the present invention.

[0131] Throughout this specification, references to "an embodiment" or "an embodiment" indicate that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Therefore, the appearance of "in an embodiment" or "an embodiment" in various places throughout the specification does not necessarily refer to the same embodiment. Furthermore, a particular feature, structure, or characteristic may be combined in any manner in one or more embodiments.

[0132] The singular forms “a” and “the” used in this specification and the appended claims include plural references unless otherwise expressly stated herein. It should be noted that the term “or” is generally used to mean “and / or” unless otherwise expressly stated herein.

[0133] In the following description, in order to clearly demonstrate the structure and working method of the present invention, a number of directional terms will be used. However, terms such as "front", "back", "left", "right", "outside", "inside", "outward", "inward", "up", and "down" should be understood as convenient terms and not as limiting terms.

[0134] This invention relates to a urine analyzer 100, as shown in Figures 1-4. The urine analyzer 100 includes a housing 1, a collector 4, a reagent kit 2 located within the housing 1, a rotary valve 102, a pump, and a detection mechanism. The rotary valve includes a microfluidic chip, a rotor 6, and a drive component 93. The reagent kit 2 is used to hold various reagents. The collector 4 has a collection chamber, which includes a sample collection chamber 411 and a water collection chamber 412. The sample collection chamber 411 is used to collect samples, while the water collection chamber 412 is used to store water. A flow channel plate 3 provides multiple flow channels for the convergence of reagents and samples. As shown in Figure 5, the detection mechanism includes a detector and a detection plate 5. The detection plate 5 has a detection chamber for receiving samples and reagents from the flow channel plate 3, and for detecting the samples within the detection chamber. The rotor 6 cooperates with the flow channel plate 3 to facilitate the collection of samples and reagents and pushes them into the detection mechanism for testing. In Figures 22-24, the drive component 93 is connected to the rotor 6 and is used to drive the rotor 6 to rotate.

[0135] Specifically, as shown in Figure 1, the outer casing 1 includes a first casing 11 and a second casing 12. The rear side of the first casing 11 and the front side of the second casing 12 are detachably connected. The "front side" or "front end" of the urine analyzer 100 is the side of the first casing 11 away from the second casing 12, and the "rear side" or "rear end" is the side of the second casing 12 away from the first casing 11. The reagent kit 2, rotor 6, and flow channel plate 3 are located inside the first casing 11, while the pump and drive unit 93 are located inside the second casing 12. The drive unit 93 and rotor 6 are detachably connected. The drive unit 93 and pump inside the second casing 12 are durable components with a long service life. The first casing 11 and the reagent kit 2, rotor 6, and flow channel plate 3 inside the first casing 11 combine to form a detection device. This detection device is a consumable item. After a period of use, when the reagents in the reagent kit 2 are exhausted, the detection device can be replaced, ensuring that resources are used efficiently and reducing waste.

[0136] In one specific embodiment, as shown in Figures 4-5, the first housing 11 includes a first front cover 111 and a first rear cover 112. The first front cover 111 and the first rear cover 112 are snapped together or fixedly connected by bolts to form an accommodating space. As shown, the first front cover 111 includes a first front connecting ring 1111 and a first front cover plate 1112 connected to the front end of the first front connecting ring 1111. The first rear cover 112 includes a first rear connecting ring 1121 and a first rear cover plate 1122 connected to the rear end of the first rear connecting ring 1121. The rear end of the first front connecting ring 1111 and the front end of the first rear connecting ring 1121 are opposite to each other and snapped together, and are also fixedly connected by bolts. The specific connection method is not limited.

[0137] As shown in Figure 4, the second housing 12 includes a second front cover 121 and a second rear cover 122. The second front cover 121 and the second rear cover 122 are fixedly connected and form another receiving space for accommodating the pump and the drive unit 93.

[0138] The front end of the second front cover 121 is provided with a recessed mounting groove 1211, as shown in FIG2. The mounting groove 1211 is used to accommodate the first rear cover 112.

[0139] In addition, as shown in Figure 8, the urine analyzer 100 also includes two locking members 13. The two locking members 13 are respectively connected to the first rear connecting ring 1121 and are symmetrically arranged on both sides of the first rear connecting ring 1121. The two locking members 13 can detachably connect the first rear cover 112 to the second front cover 121 of the second housing 12.

[0140] Specifically, as shown in Figures 6-9, the side wall of the mounting groove 1211 of the second front cover 121 is provided with two spaced locking grooves 1212. The two locking components 13 respectively include a locking tongue 131, a rotating component 132, and a handle 133. The rotating component 132 is rotatably connected to the first rear cover plate 1122 of the first rear cover 112 via a rotating shaft. The locking tongue 131 is connected to the rear end of the rotating component 132, and the handle 133 is also connected to the front end of the rotating component 132.

[0141] As shown in Figure 7, the first front connecting ring 1111 is provided with a handle clearance hole 1113. The handle 133 is plate-shaped, with its inner end connected to the front end of the rotating component 132, and its outer end extending to the outside of the first front connecting ring 1111 through the handle clearance hole 1113. As shown in Figures 2 and 6, the first rear connecting ring 1121 is provided with a latch clearance hole 1123. The inner end of the latch 131 is connected to the rotating component, and its outer end extends into the locking groove 1212 through the latch clearance hole 1123 and engages with the locking groove 1212.

[0142] As shown in Figures 2 and 6, when the first housing 11 needs to be disassembled, the handle 133 is pressed inward into the first housing 11, causing the rotating part 132 to rotate, which can move the locking tongue 131 out of the locking groove 1212. During installation, the handle 133 is rotated in the opposite direction to lock the locking tongue 131 into the locking groove 1212.

[0143] In addition, two limiting members 1124 are provided on the first rear connecting ring 1121, as shown in Figure 7. The two limiting members 1124 are located at both ends of the handle clearance hole 1113, and the inner end of the handle 133 is also provided with two protrusions 134. The two protrusions 134 are located inside the first rear connecting ring 1121 and are blocked by the two limiting members 1124 to prevent the handle 133 from disengaging from the first rear connecting ring 1121.

[0144] In other embodiments, an elastic element may be provided between the inner wall of the rotating member 132 and the first rear connecting ring 1121. This elastic element can pull the locking tongue 131 of the rotating member 132 toward the locking groove 1212 to prevent the locking tongue 131 from automatically disengaging from the locking groove 1212. Of course, in other embodiments, the locking tongue 131 and the locking groove 1212 are interference-fitted, which can also lock the locking tongue 131.

[0145] It should be understood that in other embodiments, the first housing 11 and the second housing 12 may also be snapped together, magnetically connected, or bolted together. The present invention does not limit the specific connection method of the first housing 11 and the second housing 12.

[0146] The reagent kit 2 is mounted on the first housing 11 and has multiple reagent chambers 21 for holding reagents. As shown in Figures 10-11, the reagent kit 2 is a flat plate with multiple reagent chambers 21 and multiple flow channel holes 22. The multiple reagent chambers 21 extend vertically and are arranged along a first direction, which is the width direction of the urine analyzer 100. The reagent kit 2 is plate-shaped and stacked together with the flow channel plate 3. The outer periphery of the reagent kit 2 is basically in contact with the inner wall of the first housing 11. The multiple reagent chambers 21 basically fill the entire reagent kit 2, which can hold a large amount of reagents without taking up too much space.

[0147] As shown in Figures 6 and 10, the first front connecting ring 1111 and the first rear connecting ring 1121 of the first housing 11 are both annular, that is, the inner sidewall of the first housing 11 is arc-shaped, the bottom of the reagent kit 2 is also arc-shaped, and the bottom of the multiple reagent chambers 21 are arranged around a horizontal axis, basically on the same circumference. The bottom of the multiple reagent chambers 21 is close to the bottom of the reagent kit 2 to increase the utilization rate of the reagent chambers 21.

[0148] As shown in Figure 10, the bottom wall of the reagent chamber 21 includes an inclined surface 23 and a vertical surface 24. The vertical surface 24 extends in the vertical direction, while the inclined surface 23 is an inclined surface that gradually decreases from back to front. The bottom end of the inclined surface 23 is connected to the top surface of the vertical surface 24.

[0149] The reagent chamber 21 has openings at the top and front, allowing reagents to be inserted from the top. A seal can be placed at the top of the reagent chamber 21, or an oil seal can be used. A sealing plate (not shown) is also installed at the front of the reagent kit 2, which is stacked on the front side of the kit 2 to seal the reagent chamber 21. Alternatively, if manufacturing is convenient, the sealing plate can be omitted, and the front of the sealed chamber can be designed as a sealed opening.

[0150] As shown in Figures 10 and 11, multiple flow channel holes 22 are also arranged at intervals around the horizontal axis and are recessed from the rear side of the reagent kit 2 toward the front end. The multiple flow channel holes 22 are recessed to the vertical surface 24 and communicate with multiple reagent chambers 21. The inclined surface 23 is designed to facilitate the slow flow of reagents into the bottom end and into the flow channel plate 3 from the flow channel holes 22.

[0151] As shown in Figures 10 and 11, the rear side of the reagent kit 2 is also provided with multiple sealing grooves 25. The multiple sealing grooves 25 are formed by the recesses on the rear side of the reagent kit 2, and the multiple flow channel holes 22 are formed by the recesses of the multiple sealing grooves 25 away from the inner wall of the second shell 12 to the vertical surface 24. The sealing grooves 25 can also be set in a conical shape, that is, the sealing grooves 25 gradually decrease in size from back to front, and the external opening is relatively large.

[0152] As shown in Figures 7 and 12, the microfluidic chip 101 includes a flow channel plate 3 and a capping plate 7 stacked on the front side of the flow channel plate 3. The capping plate 7 is located on the rear side of the reagent kit 2 and is a thin plate stacked on the rear side of the reagent kit 2 and the front side of the flow channel plate 3. The front side of the capping plate 7 is provided with multiple tapered insertion posts 71, which are located in multiple sealing grooves 25. Multiple sealing rings are fitted around the multiple insertion posts 71, so that the multiple insertion posts 71 and the multiple sealing grooves 25 are sealed together.

[0153] As shown in Figures 7 and 12, the rear side of the cover plate 7 is also provided with multiple through holes 72. The multiple through holes 72 extend to the front end of multiple plugs and are respectively connected to multiple flow channel holes 22. The reagent in the reagent chamber 21 can flow into the flow channel plate 3 through the flow channel holes 22 and the through holes 72 of the plug 71.

[0154] The sealing plate 7 and the reagent kit 2 can be snapped together or bonded together, or connected by thermoplastic means. This invention does not limit the specific connection method between the sealing plate 7 and the reagent kit 2.

[0155] In the embodiment shown in Figures 11-13, the bottom end of the reagent kit 2 is provided with a slot 26, and the bottom end of the sealing plate 7 is provided with a protruding buckle 73. The buckle 73 can be inserted into the slot 26 of the reagent kit 2, thereby enabling the reagent kit 2 and the sealing plate 7 to be quickly assembled.

[0156] The flow channel plate 3 is stacked on the rear side of the cover plate 7. The flow channel plate 3, the cover plate 7, and the reagent kit 2 are fixedly connected to the first front cover plate 1112 or the first rear cover plate 1122 of the first housing 11 by the same bolt. In the embodiments shown in Figures 4 and 7, the inner walls of the first front cover plate 1112 and the first rear cover plate 1122 of the first housing 11 are respectively provided with two mounting posts 14. The mounting posts 14 of the first front cover plate 1112 and the first rear cover plate 1122 abut against each other and are both provided with threaded holes. The threaded holes of the mounting posts 14 of the first rear cover plate 1122 extend to the rear side of the first rear cover plate 1122. The bolt can be screwed into the threaded holes of the mounting posts 14 of the first front cover plate 1112 from the rear side of the first rear cover plate 1122, thereby fixing the first rear cover plate 1122 and the first front cover plate 1112.

[0157] Furthermore, as shown in Figure 7, the reagent kit 2 is provided with a countersunk hole 27, and the first rear cover plate 1122 is also provided with an additional mounting post 14. The threaded hole of the mounting post 14 is opposite to the countersunk hole 27, and the inner end of the mounting post 14 is also provided with a flange, a portion of which can abut against the rear side of the flow channel plate 3. By screwing the bolt into the countersunk hole 27 from the rear side of the first rear cover plate 1122, the reagent kit 2, the capping plate 7, and the flow channel plate 3 can be fixed together on the first rear cover plate 1122, making the reagent kit 2, the capping plate 7, and the flow channel plate 3 fit tightly together.

[0158] The front side of the flow channel plate 3 is provided with a central hole 31, multiple circumferential holes 32, a common flow channel 33, a sample flow channel, a clear water flow channel, an air flow channel 36, multiple reagent flow channels 37, and a detection flow channel 38, as shown in Figures 14-16. The central hole 31 is located on the aforementioned horizontal axis and is a through hole 72 penetrating the front and back of the flow channel plate 3. The multiple circumferential holes 32 are located on a circumference centered on the central hole 31 and are arranged at intervals, that is, the multiple circumferential holes 32 are on the same circumference.

[0159] The inner ends of the sample channel, the water channel, the air channel 36, the detection channel 38, and the reagent channels 37 extend to and communicate with the multiple circumferential holes 32, respectively. The outer ends of the sample channel, the water channel, the air channel 36, the detection channel 38, and the reagent channels 37 are dispersed away from the central hole 31 to other positions of the channel plate 3. The outer end of the detection channel 38 is connected to the detection chamber of the detection mechanism, which facilitates the flow of samples and reagents from the detection channel 38 into the detection chamber. The outer ends of the reagent channels 37 extend to another circumference and are aligned and connected with the multiple through holes 72 of the multiple cover plates 7.

[0160] In some embodiments, a clear water channel and a sample channel are respectively provided. The outer end of the clear water channel is connected to the clear water collection chamber 412 of the collection chamber through a pipe, so that water can enter the clear water channel from the clear water collection chamber 412. The sample channel is connected to the sample collection chamber 411 through a pipe, so that the sample can enter the sample channel from the sample collection chamber 411.

[0161] In the embodiments shown in Figures 14 and 16, two water channels and two sample channels are provided respectively, and the inner ends of the two water channels and the two sample channels are connected to different circumferential holes 32. The usage of the two water channels and the two sample channels will be described in detail below.

[0162] To facilitate communication between the sample flow channel, detection flow channel 38, reagent flow channel 37 and air flow channel 36 and the sample collection chamber 411, detection chamber and reagent chamber 21, a first adapter 301 is also installed on the rear side of the flow channel plate 3. The first adapter 301 can be installed in the first housing 11 or in the second housing 12.

[0163] Specifically, as shown in Figures 18 and 19, if the first adapter 301 is installed inside the first housing 11, the first adapter 301 can be snapped onto the rear side of the flow channel plate 3, fixedly connected by bolts, or welded, etc., without limiting the specific connection method between the first adapter 301 and the rear side of the flow channel plate 3.

[0164] The first adapter 301 is used to introduce samples and water into the microfluidic chip, and also to discharge waste liquid from the detection plate into the collector, and then from the collector into the toilet. Moreover, when the reagents are used up, the first adapter 301 and the tubing can be disassembled together, and all components in the new first housing can be directly replaced, reducing contamination and extending the service life of the urine analyzer.

[0165] As shown in Figures 18, 26, and 27, the first adapter 301 is provided with seven adapter pipes. The seven adapter pipes are used to communicate with the sample collection chamber 411, the clean water collection chamber 412, the drain channel 416 of the detector, or the external air through multiple pipes. The adapter pipes are preferably located at the top of the first adapter 301 to facilitate the flow of samples or water from the sample collection chamber 411 or the clean water collection chamber 412 into the flow channel plate 3, and also to facilitate the flow of liquid in the detection chamber into the drain channel 416 of the collector from the connecting pipe and the pipe.

[0166] As shown in Figures 18, 26, and 27, of the seven connecting pipes, two are connected to the sample collection chamber 411 of the collector, and are defined as sample connecting pipes 3011. Two other connecting pipes are connected to the clean water collection chamber 412 of the collector, and are defined as clean water connecting pipes 3012. Another connecting pipe is connected to the air flow channel 36 of the flow channel plate 3, and is defined as air connecting pipe 3013. Another connecting pipe is connected to the sewage discharge channel 416 of the collector, and is defined as sewage discharge connecting pipe 3014. The last connecting pipe is connected to the drive pipe, and is defined as drive connecting pipe 3015.

[0167] As shown in Figure 18, the front side of the first adapter 301 is provided with seven first slots 3016, and the first adapter 301 has seven channels, which extend in the opposite direction and communicate with the seven adapter pipes. The bottom ends of the seven channels are connected to the multiple first slots 3016.

[0168] As shown in Figures 14 and 17, the rear side of the flow channel plate 3 is also provided with nine first adapter posts 3017. Each of the nine first adapter posts 3017 has a first adapter hole, which extends into the flow channel plate 3 and communicates with the water channel, detection channel 38, sample channel, or air channel 36 of the flow channel plate 3. Seven of the nine first adapter posts 3017 are inserted into the seven first slots 3016 of the first adapter component, while the other two need to be inserted into the inlet and outlet of the detection plate. Of these seven first adapter posts, the first adapter holes of two of the first adapter posts 3017 communicate with the two sample channels of the flow channel plate 3, and these two first adapter holes also communicate with the two sample adapter pipes 3011. The first adapter holes of the other two first adapter posts 3017 communicate with the two water channels and also communicate with the two water adapter pipes 3012.

[0169] As shown in Figures 14, 17, and 18, the first adapter hole of one of the first adapter posts 3017 is connected to the air flow channel 36 and the air adapter pipe 3013. The first adapter hole of another first adapter post 3017 is connected to the drive pipe and the drive adapter pipe 3015. There are also three first adapter holes of the first adapter posts 3017, one of which is used to connect to the sewage adapter pipe 3014, and the other two are used to connect to the detection chamber respectively. These will be described in detail below.

[0170] In summary, the seven first adapter posts 3017 are respectively inserted into the seven first slots 3016 of the first adapter, thereby connecting the outer end of the sample flow channel of the flow channel plate 3 to the sample adapter pipe 3011, the outer end of the clean water flow channel to the clean water adapter pipe 3012, the outer end of the air flow channel 36 to the air adapter pipe 3013, and the outer end of the detection flow channel 38 to the sewage adapter pipe 3014.

[0171] In another embodiment, the first adapter 301 is installed inside the second housing 12 or in the mounting slot. Since the second housing 12 and the first housing 11 are detachably connected, regardless of whether the first adapter 301 is connected inside or outside the second housing 12, the plurality of first slots 3016 of the first adapter 301 need to be exposed in the mounting slot 1211 of the second housing 12.

[0172] As shown in Figure 17, the rear side of the flow channel plate 3 is also provided with multiple first adapter posts 3017, and the first rear cover plate 1122 of the first housing 11 also needs to be provided with avoidance holes to avoid multiple first adapter posts 3017, so that the first adapter posts 3017 can be inserted into the first slot 3016 of the first adapter 301 as the first housing 11 and the second housing 12 are assembled.

[0173] As shown in Figures 6, 17, and 18, when the first housing 11 and the second housing 12 are assembled, when the locking tongue 131 of the locking member 13 is inserted into the locking groove 1212, it can simultaneously squeeze multiple first adapter pins 3017 into multiple first slots 3016.

[0174] Of course, in order to increase the sealing performance of the first adapter 301 and the flow channel plate 3, a sealing ring fitted around the first adapter post 3017 is also required in the first slot 3016.

[0175] As shown in Figures 18 and 19, the detection plate 5 can be installed inside the first housing 11 and fixedly connected or snapped to the first adapter 301, or fixedly connected to the rear side of the flow channel plate 3. Of course, in other embodiments, the detection plate 5 can also be disposed inside the second housing 12 and configured to be snapped and detached from the first adapter 301.

[0176] As shown in Figures 14 and 19, if installed inside the first housing 11, the detection plate 5 can be directly fixedly connected to the rear side of the flow channel plate 3. One end of the detection chamber is connected to the detection flow channel 38, and the other end is connected to the sewage transfer pipe 3014 of the first adapter 301. The sewage transfer pipe 3014 is connected to the sewage channel 416 of the collector through a pipe. The liquid in the detection flow channel 38 flows into the detection chamber for detection. After the detection is completed, the liquid in the detection chamber can flow from the sewage transfer pipe 3014 into the sewage channel 416 and be discharged into the toilet from the sewage channel 416.

[0177] Specifically, as shown in Figures 5, 19, and 21, the detection plate 5 is a plate extending along the front and back of the urine analyzer 100. The detection chamber is roughly U-shaped and has an inlet 51 and an outlet 52, which are located at the front end of the detection plate 5. As shown in Figure 17, the flow channel plate 3 has three first adapter posts 3017 on its rear side. Two of the first adapter posts 3017 are inserted into the inlet 51 and the outlet 52, respectively. The first adapter post 3017 inserted into the inlet 51 connects the detection flow channel 38 of the flow channel plate 3 with the inlet 51. The sample and liquid in the detection flow channel 38 can flow into the detection chamber from the inlet 51 for detection. That is, one end of the detection chamber is connected to the detection flow channel, and the other end is connected to the drain pipe.

[0178] As shown in Figures 14, 17, and 18, the flow channel plate 3 is also provided with a sewage discharge channel 302. Both ends of the sewage discharge channel 302 are connected to two other first adapter posts 3017 on the rear side of the flow channel plate 3. One of the two first adapter posts 3017 is inserted into the outlet 52 of the detection chamber, and its first adapter hole is connected to the outlet 52. The other first adapter post 3017 is inserted into the first slot 3016 at the front end of the first adapter 301 and is connected to the sewage discharge adapter pipe 3014 located at the top of the first adapter 301.

[0179] In other words, the mixture of sample and reagent in the detection channel 38 flows into the detection chamber from the first adapter hole of one of the first adapter columns 3017 and the inlet 51 of the detection chamber. After the detection is completed, the mixture flows into the drain channel 302 of the channel plate 3 from the outlet 52, and then into the drain adapter 3014 from the drain channel 302. From the drain adapter 3014 and the pipe, it flows into the drain channel 416 of the collector, and then into the toilet from the drain channel 416.

[0180] The drain channel 302 functions as a transfer channel, with one end connected to the outlet 52 of the detection chamber and the other end connected to the drain transfer pipe 3014. The mixed liquid in the detection chamber flows through the drain channel 302 and then into the drain channel 416 through the drain transfer pipe 3014. This design reduces the volume of the first adapter 301 and makes full use of the internal space of the channel plate 3 and the first adapter 301.

[0181] If the detection plate 5 is installed inside the first housing 11, it can be removed along with the first housing 11 when the reagents inside the first housing 11 are exhausted. When replacing with a new detection device, a new detection plate 5 is also installed inside it.

[0182] The detector of this invention includes a light source and a photosensitive sensor, which are respectively disposed at corresponding positions on the detection plate 5. The detection plate 5 is made of transparent material. The light source is an LED light source used to illuminate the mixed liquid in the detection chamber, while the photosensitive sensor is used to sense the light emitted by the light source after illuminating the mixed liquid, in order to detect the sample components. However, the detector installation is relatively complex. Therefore, for ease of assembly by the customer, the detector needs to be installed inside the second housing 12, that is, the detector and the detection plate 5 are assembled separately. Since the detector needs to be close to the detection plate 5 to detect the mixed liquid in the detection chamber, the rear end of the detection plate 5 needs to extend into the second housing 12.

[0183] Specifically, as shown in Figure 20, the first rear cover plate 1122 of the first housing 11 and the mounting groove 1211 of the second housing 12 need to be provided with clearance holes. These clearance holes are detection plate clearance holes 15. The front end of the detection plate 5 is connected to the flow channel plate 3 and the first adapter 301, and the rear end extends from the two detection plate clearance holes 15 of the first housing 11 and the second housing 12 into the second housing 12. The detector is installed at the top or bottom of the detection plate clearance hole 15 of the second housing 12 and can detect the liquid in the detection chamber.

[0184] In another embodiment, the detection plate 5 can also be directly installed in the second housing 12. The front end of the detection plate 5 extends to the inner wall of the mounting groove 1211. Among the three first adapter posts 3017 at the rear end of the flow channel plate 3, the first adapter holes of two of the first adapter posts 3017 are respectively connected to both ends of the sewage flow channel 302. The first adapter hole of one of the two first adapter posts 3017 is connected to the sewage adapter pipe 3014, and the other is connected to the outlet 52 of the detection chamber.

[0185] Of the three first adapter posts 3017, the first adapter hole of another first adapter post 3017 is connected to the inlet 51 of the detection cavity.

[0186] The two first adapter posts 3017, which are connected to the inlet 51 and outlet 52 of the detection chamber, need to extend to the rear side of the first rear cover plate 1122 of the first housing 11. When the first housing 11 and the second housing 12 are assembled, the rear ends of the two first adapter posts 301 can be inserted into the two inlets 51 and outlet 52 at the front end of the detection plate 5, which can also achieve quick disassembly and assembly.

[0187] It should be understood that multiple adapter pipes and multiple first adapter posts 3017, or the first adapter post and the outlet 52 and the inlet 51, all require sealed connections. The sealing method can be a sealing ring or other methods.

[0188] The common flow channel 33 is a curved flow channel, with its inner end extending to the central hole 31 and communicating with the central hole 31. Its outer end circles the central hole 31 once within the circle formed by multiple circumferential holes 32 and then bends and extends to the outside of the flow channel plate 3. The common flow channel 33 and the multiple circumferential holes 32 are staggered and are not directly connected to each other.

[0189] In one embodiment, the outer end of the common flow channel 33 is used to communicate with the drive pipe 94, which is located inside the second housing and connected to a pump that can extract air from the drive pipe 94 and the common flow channel 33. Of course, in some embodiments, two pumps can be connected in series via pipes, with one pump connected to the drive pipe 94.

[0190] In the embodiment shown in Figure 14, the middle part of the common flow channel 33 has at least one bend, which increases the volume of the common flow channel 33 on the one hand, and helps to prevent reagents or samples in the common flow channel 33 from flowing back into the drive pipe on the other hand.

[0191] The common flow channel 33 needs to be connected to the drive pipe 94, and the pump is connected to the drive pipe. After the pump is started, it can vent the air in the common flow channel 33 and form a negative pressure.

[0192] The pump and drive pipe are located inside the second housing 12. Therefore, in order to allow for quick disassembly and reassembly of the drive pipe and the common flow channel 33, a second adapter 306 needs to be installed. The second adapter 306 will be described below.

[0193] As a preferred embodiment, to achieve more accurate quantitative extraction of reagents and samples, two pumps can be used, each connected to a common flow channel via two separate drive pipes: a peristaltic pump 91 and a plunger pump 92. The two pumps are respectively installed within the second housing 12 and connected to the two drive pipes. These two drive pipes are defined as the first drive pipe and the second drive pipe, respectively.

[0194] The second drive pipe is connected to the plunger pump, and the first drive pipe is connected to the peristaltic pump 91. The first drive pipe includes two sections, the two ends of which are respectively connected to the two ends of the hose of the peristaltic pump, and the other two sections are respectively connected to the two peristaltic pump adapters 3041 described below.

[0195] The front side of the flow channel plate 3 also has a drive flow channel 303, which extends vertically and its top end is connected to a first adapter hole of one of the first adapter posts 3017, which is connected to the drive adapter pipe 3015.

[0196] The rear side of the flow channel plate 3 is also provided with three second adapter posts, each of which is provided with a second adapter hole. Among the three second adapter posts, two are peristaltic pump adapter posts 3041 and the other is plunger pump adapter post 3042.

[0197] As shown in Figures 14 and 17, the second adapter hole of one of the two peristaltic pump adapter pins 3041 is connected to the bottom end of the drive flow channel 303, and the second adapter hole of the other peristaltic pump adapter pin 3041 is connected to the common flow channel 33.

[0198] The plunger pump adapter 3042 is located between the two peristaltic pump adapters 3041, and its second adapter hole is also connected to the common flow channel 33.

[0199] As shown in Figures 17 and 18, the second adapter 306 is connected to the inner wall of the mounting groove 1211 of the second housing 12, and is provided with three second slots 3061. Among the three second slots 3061, two of the second slots 3061 respectively accommodate two peristaltic pump adapter columns 3041. That is, the common flow channel 33 is connected to one end of a section of the first drive pipe through one peristaltic pump adapter column 3041, and one end of the other section of the first drive pipe is connected to the bottom end of the drive flow channel 303 through another peristaltic pump adapter column 3041. The top end of the drive flow channel 303 is connected to the drive adapter pipe 3015 through the first connecting column. The drive adapter pipe 3015 can also be connected to the collector. In other words, one end of each section of the first drive pipe is connected to both ends of the peristaltic pump hose, and the other end is connected to the common flow channel and the drive adapter pipe 3015 respectively. After the peristaltic pump is started, it can draw the fluid in the common flow channel from the first drive pipe and the drive adapter pipe to the collector, and then discharge it from the collector into the toilet.

[0200] Of the three second slots 3061, another second slot 3061 is connected to one end of the second drive pipe, and this second slot 3061 accommodates the plunger pump adapter 3042.

[0201] The peristaltic pump 91 is used to drive the air out of the common flow channel 33, or to drive the sample and water in the sample collection chamber into the sample flow channel and the clean water flow channel. That is to say, a large air flow is required. Therefore, a drive flow channel 303 is provided on the flow channel plate 3, and a drive adapter pipe 3015 is provided on the first adapter 301. If the design is bent, a large air flow can be provided. The plunger pump 92 only needs to quantitatively extract the sample and reagent from the sample flow channel and the reagent flow channel 37 into the common flow channel. The required flow is smaller. Therefore, one end of the second drive pipe is connected to the common flow channel 33, and the other end is located near the plunger pump 92.

[0202] As shown in Figure 5, the detection channel 38 is connected to the detection chamber, and a mixing chamber 39 is also provided along the path of the detection channel 38. The mixing chamber 39 is connected to the detection channel 38, and the width of the mixing chamber 39 is larger than the diameter of the detection channel 38. When the sample and reagent flow in the detection channel 38, they pass through the mixing chamber 39. Due to the larger width of the mixing chamber 39, the sample and reagent will be accelerated when flowing from the detection channel 38 into the mixing chamber 39, and thus be mixed in the mixing chamber 39.

[0203] As a preferred embodiment, the mixing cavity 39 includes a mixing bend 392 and at least one mixing chamber 391 that are connected to each other. The mixing bend 392 is an S-shaped bend, and the mixing chamber 391 and the mixing bend 392 are connected. The width of the mixing cavity 39 is greater than the diameter of the mixing bend 392 and the detection channel 38.

[0204] In the embodiment shown in Figures 14-16, the mixing cavity 39 includes three mixing bends 392 and three mixing chambers 391. The three mixing chambers 391 and the three mixing bends 392 are arranged alternately and are interconnected. The inlet of the mixing cavity 39 is at the bottom and the outlet is at the top. That is, the three mixing bends 392 and the mixing cavity 39 extend upward in a curved manner.

[0205] The mixing bend 392 includes at least two horizontal flow channels and at least one turning flow channel 394, with any one of the turning flow channels 394 located at both ends of the two horizontal flow channels;

[0206] The mixing bend 392 is an S-shaped bend and includes at least two horizontal flow channels and at least one turning flow channel 394. The horizontal flow channels are flow channels that extend in the horizontal direction, while the turning flow channel 394 is located between any two horizontal flow channels, that is, at the corner of the mixing bend 392.

[0207] As shown in Figure 16, the turning channel 394 includes a curved inner arc 395 and an outer arc 396. Both the inner arc 395 and the outer arc 396 are arc-shaped, and the inner diameter of the inner arc 395 is smaller than the inner diameter of the outer arc 396.

[0208] The mixing chamber 39 of the present invention is equipped with an S-shaped mixing bend 392 and a mixing chamber 39. The outer diameter is enlarged at the turning corner of the mixing bend 392. By utilizing the bend with a change in diameter, the flow velocity at the outer arc 396 is greater than the flow velocity at the inner arc 395, forming a local Dean flow effect, which improves the mixing effect of the sample and reagent liquid in the flow channel.

[0209] As shown in Figure 15, the vertical cross-section of the mixing chamber 391 is approximately circular, and the two side walls of the mixing chamber 391 are also arc surfaces. The two arc surfaces are a first arc surface 397 and a second arc surface 398 opposite to the first arc surface 397. Both the first arc surface 397 and the second arc surface 398 are arc surfaces that protrude outward.

[0210] As a preferred embodiment, as shown in Figure 15, the first arc surface 397 and the second arc surface 398 are circular arc surfaces with the same diameter and arc length, and the tangents at both ends of the first arc surface 397 and the second arc surface 398 are parallel to each other. In the embodiment shown in the figure, the arc length of the first arc surface 397 is equal to 1 / 4 of the circumference, and the tangents at both ends are perpendicular to each other, with one tangent extending vertically and the other extending horizontally.

[0211] As the entire mixing chamber 39 extends and bends vertically, as shown in Figure 16, each mixing chamber 391 is located between two mixing bends 392. Each mixing chamber 39 needs to be connected to the horizontal flow channels of the two mixing bends 392. The two horizontal flow channels are respectively set in a mirror symmetric manner, one of which is located at the top of the mixing chamber 391 and the other is located at the bottom of the mixing chamber 391.

[0212] Of the two horizontal channels connected to the mixing chamber 391, one is defined as the inlet horizontal channel 3931, and the other as the outlet horizontal channel 3932. The inlet horizontal channel 3931 is connected to the top of the mixing chamber 391, while the outlet horizontal channel 3932 is connected to the bottom of the mixing chamber 391. Samples or reagents flow into the mixing chamber 391 from the inlet horizontal channel 3931 and then out from the outlet horizontal channel 3932. That is, the inlet horizontal channel 3931 is located upstream of the outlet horizontal channel 3932. Samples and reagents flow into the detection channel 38 from the common channel 33, and after passing through, for example, the mixing chamber 39, enter the mixing chamber 391 through the inlet horizontal channel 3931 of a mixing bend 392, and then flow into the horizontal channel of the other mixing bend 392.

[0213] As shown in Figure 15, the mixing chamber 391 has an inlet 3911 and an outlet 3912. The inlet 3911 is connected to the inlet horizontal flow channel of one of the mixing bends, and the outlet 3912 is connected to the outlet horizontal flow channel 3932 of another mixing bend. Samples and reagents can flow into the mixing chamber from the inlet horizontal flow channel of one of the mixing bends and the inlet 3911, and then flow into another mixing bend from the outlet 3912 and the outlet horizontal flow channel, continuously flowing within several mixing chambers and several mixing bends.

[0214] The line connecting the inlet horizontal flow channel 3931 and the outlet horizontal flow channel 3932 serves as a dividing line, as shown by the dashed line in Figure 15. This dividing line divides the mixing chamber 391 into two parts. The area formed by this dividing line and the lower first arc surface 397 is the slow zone 3934, and the area between the dividing line and the second arc surface 398 is the fast zone 3933. The flow from the inlet horizontal flow channel 3931 into the mixing chamber 391 in the fast zone 3933 and the slow zone 3934 has a certain speed difference. The mixed liquid of the sample and reagent forms a vortex around the center point within the circular mixing chamber 391, which increases the contact area between the liquids and improves the mixing effect.

[0215] As the horizontal flow channel 3932 narrows, the velocity of the sample and reagent mixture increases sharply when it flows out of the horizontal flow channel 3932. The sample and reagent mixture is relatively compressed, further increasing the mixing intensity. Through the series connection of the above-mentioned multiple diameter-changing mixing bends 392 with the circular mixing chamber 391, the mixing intensity is gradually increased until the detection chamber, where the sample and reagent are essentially completely mixed.

[0216] The mixing chamber 39 of this invention is commonly used in the fields of microfluidic chip technology, such as biology and chemistry. When samples or reagents or samples and reagents need to be mixed, this structure can greatly improve the mixing efficiency while avoiding some residue and bubble problems.

[0217] Inside the mixing chamber 39, the inlet horizontal flow channel 3931, which is connected to each mixing chamber 391, is set higher than the outlet horizontal flow channel 3932. In special application scenarios, such as when it needs to be used vertically, when the liquid flows from bottom to top, there is no need to consider the influence of gravity, so there will be no residue problem in the mixing chamber 391.

[0218] When samples or reagents flow in relatively rough flow channels, air bubbles are easily generated, which affects the mixing effect and may even be carried into the detection chamber, causing analytical errors. In this application, multiple mixing chambers 39 are connected in series with mixing bends 392. The corners of each mixing bend 392 are treated with smooth rounded transitions, which can avoid and eliminate air bubbles in the mixing chamber 391 to a certain extent.

[0219] The inlet of the mixing chamber 39 is located below the outlet, and the mixing chamber 39 is located above the common flow channel 33. The inlet of the mixing chamber 39 is connected to the common flow channel 33, and the outlet is connected to the detection chamber. The sample and reagent in the common flow channel 33 flow into the mixing chamber 39 from the bottom inlet and then flow into the detection chamber from the outlet.

[0220] As shown in Figures 14 and 22, the rotor 6 is rotatably mounted inside the first housing 11 and located on the rear side of the flow channel plate 3. The rotor 6 has a transfer channel inside, with its inner end 61 and outer end opening towards the front side of the rotor 6. The transfer channel is roughly U-shaped, with its inner end 61 aligned with the central hole 31. The inner end is recessed from the front side of the rotor 6 into the interior of the rotor 6. The outer end 62 of the transfer channel also opens towards the front side of the rotor 6, and the distance from the outer end 62 to the inner end 61 is the same as the distance between the central hole 31 and the multiple circumferential holes 32.

[0221] As shown in Figures 14 and 22, the inner end 61 of the transfer channel is aligned with and connected to the central hole 31, and the outer end 62 rotates with the rotor 6 and can be aligned with and connected to any one of the circumferential holes 32 as the rotor 6 rotates.

[0222] When a sample needs to be extracted, the rotor 6 rotates, aligning the outer end 62 of the transfer channel with the circumferential hole 32 that connects to the inner end of the sample flow channel. At this time, both ends of the transfer channel are connected to the sample flow channel and the common flow channel 33, respectively. The peristaltic pump 91 can extract the air from the common flow channel 33, the transfer channel, the sample flow channel, and the external sample transfer pipe or the pipe connected to the transfer pipe, forming a negative pressure, and drawing the sample in the sample collection chamber 411 to the common flow channel 33.

[0223] When reagents need to be extracted, the same operation is performed: the rotor 6 is rotated so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 that is connected to the reagent flow channel 37, so that the common flow channel 33 is connected to the reagent channel. The peristaltic pump 91 discharges the air in the common flow channel 33 and the reagent channel, forming a negative pressure, and draws the reagent in the reagent chamber 21 into the common flow channel 33.

[0224] The same procedure applies when it is necessary to extract clean water from the clean water collection chamber 412, and will not be described in detail here.

[0225] After the sample and reagent are drawn into the common flow channel 33, the rotor 6 continues to rotate, so that the outer end 62 of the transfer channel is aligned with the circumferential hole 32 that is connected to the inner end of the detection flow channel 38. The peristaltic pump 91 drives the sample and reagent in the common flow channel 33 to flow from the common flow channel 33 into the detection flow channel 38, and then from the detection flow channel 38 into the detection chamber.

[0226] In the embodiment where the mixing chamber 39 is provided, the peristaltic pump 91 can push the sample and reagent from the detection inlet into the mixing chamber 39, pushing the sample and reagent from the bottom inlet to the top outlet of the mixing chamber 39. To improve the mixing effect, the peristaltic pump 91 can also be used to repeatedly backflow the sample and reagent through the mixing chamber 391 and the mixing bends 392. After passing through the mixing chamber 391 and multiple mixing bends 392, the sample and reagent are repeatedly mixed to form a mixed liquid until the mixing effect is achieved. Finally, the mixed liquid flows into the detection chamber from the inlet 51 of the detection chamber.

[0227] As described above, the flow channel plate 3 is also provided with a sewage discharge channel 302. Both ends of the sewage discharge channel 302 are respectively connected to the first adapter holes of two other first adapter posts 3017 on the rear side of the flow channel plate 3. One of the two first adapter posts 3017 is inserted into the outlet 52 of the detection chamber, and the first adapter hole of this first adapter post 3017 is connected to the outlet hole. The other first adapter post 3017 is inserted into the first slot 3016 at the front end of the first adapter 301 and is connected to the sewage discharge adapter pipe 3014 located at the top of the first adapter 301.

[0228] After the test is completed, the pump drives air into the test channel 38 and the test chamber, and the mixed liquid flows from the outlet 52 of the test chamber into the sewage channel 302, and then from the sewage channel 302 into the sewage transfer pipe 3014. From the sewage transfer pipe 3014 and the pipe, it flows into the sewage channel 416 of the collector, and then into the toilet.

[0229] The rotor 6 is rotatably connected to the rear side of the flow channel plate 3. In a specific embodiment, the rear side of the flow channel plate 3 is also provided with a connector 85. The connector 85 is a ring extending around the outside of multiple circumferential holes 32 and is located on the radial outer side of the rotor 6.

[0230] The rotor 6 is also covered by a protective cover 81, as shown in Figures 22 and 23. The protective cover 81 covers the connector 85 and is also snapped into the connector 85. The rotor 6 rotates under the protective cover 81.

[0231] Furthermore, as shown in Figures 22 and 23, in order to drive the rotor 6 against the rear side of the flow channel plate 3 and prevent liquid from overflowing from the circumferential hole 32, a compression spring 82 is also provided inside the protective cover 81. A convex ring 83 is also provided on the rear side of the rotor 6. The compression spring 82 is sleeved around the convex ring 83, and its front and rear ends abut against the rear side of the rotor 6 and the rear wall of the protective cover 81, thereby ensuring a tight fit between the rotor 6 and the flow channel plate 3. Of course, the compression spring 82 can also be replaced with other biasing components, such as magnets attracting each other on the rotor 6 and the flow channel plate 3.

[0232] The drive unit 93 is located inside the second housing 12 and is detachably connected to the rotor 6, as shown in Figure 24. The drive unit 93 can be a motor, or other drive methods can be selected. The motor shaft extends into the mounting slot 1211 of the second housing 12. After the second housing 12 and the first housing 11 are assembled, the motor shaft and the rotor 6 can be automatically assembled.

[0233] Specifically, the first rear cover plate 1122 of the first housing 11 has a clearance hole for the protective cover 81, and the inner wall of the mounting groove 1211 of the second housing 12 also has a clearance hole for the motor shaft. The rear side of the protective cover 81 is located in the clearance hole of the first rear cover plate 1122 and also has a through hole, while the shaft of the drive member 93 extends from the clearance hole in the inner wall of the mounting groove 1211 into the protective cover 81. In addition, the rear side of the convex ring 83 has a recessed spline groove 84, as shown in Figures 23 and 24, and the front end of the motor shaft has a spline 931 located in the spline groove 84. When the first housing 11 and the second housing 12 are assembled, the spline 931 of the shaft is inserted into the spline groove 84 to complete the assembly.

[0234] The collector is located outside the first housing 11 and the second housing 12, and is connected to the adapter pipe of the first adapter 301 through multiple pipes.

[0235] In the embodiment shown in Figures 25-27, the collector includes a collection plate 41, an outer cover plate 43, an inner cover plate 42, and a clean water collection component. The collection plate 41 is disc-shaped and has an outer side and an inner side. The outer side is the side away from the toilet, while the inner side is the side closer to the toilet. A sample collection chamber 411 is provided on the outer side of the collection plate 41, and a clean water collection chamber 412 is provided on the rear side.

[0236] The sample collection chamber 411 is located at the top of the collection plate 41 and its width gradually increases from the bottom to the top, opening towards the top of the collection plate 41 for collecting samples. The water collection chamber 412 is located at the bottom of the collection plate 41 and is offset from the sample collection chamber 411.

[0237] The top of the collection plate 41 is also provided with a water inlet channel 413, a water outlet channel 414, and a sample outlet channel 415. The water inlet channel 413 and the water outlet channel 414 are respectively connected to the clean water collection chamber 412. The water inlet channel 413 and the water outlet channel 414 are both located on the rear side of the collection plate 41 and are recessed from the top of the collection plate 41 into the clean water collection chamber 412.

[0238] The sample collection cavity 411 is located on the front side of the collection plate 41, and is formed by the recess in the front side of the collection plate 41. The sample collection cavity 411 is formed by connecting and assembling the collection plate 41 and the outer cover plate 43. The top of the front cover plate is provided with a filter part 44, which is a grid spaced at the top of the front cover plate. A filter screen or other filter can also be added to filter foreign objects.

[0239] The inner walls on both sides of the sample collection cavity 411 are curved surfaces that protrude towards each other, causing the width of the sample collection cavity 411 to gradually increase from the bottom to the top. In addition, the curved inner walls can increase the opening of the sample collection cavity 411 and facilitate the flow of the sample from the top to the bottom.

[0240] The inner wall of the sample collection cavity 411 is also provided with two recessed drainage grooves 4111. The two drainage grooves 4111 are formed by recesses from the top of the collection plate 41 downwards and are spaced apart. A baffle post 402 is formed between the two drainage grooves 4111. The baffle post 402 is basically located in the middle of the sample collection cavity 4111, and the two drainage grooves 4111 are also basically the same in shape. The bottom wall of the two drainage grooves 4111 is also a downward-facing concave arc surface.

[0241] The drainage channel 4111 facilitates the reception of more samples and also facilitates the flow of samples along the inner wall of the drainage channel 4111. It provides a larger flow channel arc surface, which facilitates the slow flow of samples into the bottom of the sample collection cavity 411 and reduces the generation of air bubbles.

[0242] It should be understood that if the sample collection cavity 411 has sufficient space, multiple drainage channels 4111 can be provided. The multiple drainage channels 4111 can be arranged at intervals along the width direction of the collector. The inner wall and bottom wall of the multiple drainage channels 4111 are preferably smooth arc surfaces for sampling.

[0243] The bottom of the sample collection chamber 411 is also provided with a drain port 417. The drain port 417 is open towards the bottom of the collection chamber and has a very small diameter. During the sample collection process, the drain port 417 is always open. Because of its small diameter, it will not affect the sample collection.

[0244] The sample collection chamber 411 is also equipped with a liquid level sensor, which is located below and adjacent to the two drainage channels 4111, and is used to sense the liquid level of the sample collection.

[0245] Furthermore, the sample outlet channel 415 is formed by a recess on the rear side of the collection plate 41, with its bottom end extending into the sample collection chamber 411 and located above the drain outlet 417. Its top end is located at the top of the collection plate 41, and the top end of the sample outlet channel 415 is connected to the sample transfer tube 3011 via a pipe. Samples within the sample collection chamber 411 can flow into the sample flow channel from the sample outlet channel 415 and the sample transfer tube 3011.

[0246] The clean water collection chamber 412 is formed by the recess on the rear side of the collection plate 41. After the inner cover plate 42 is connected to the rear side of the collection plate 41, the inner cover plate 42 covers the clean water collection chamber 412 to form a closed cavity.

[0247] The water collection chamber 412 includes a first chamber 4121 and a second chamber 4122. The first chamber 4121 and the second chamber 4122 are located on both sides of the sample collection chamber 411 and are connected at the bottom. The first chamber 4121 and the second chamber 4122 are symmetrically arranged, and exhaust holes 418 are respectively provided at the top.

[0248] The water inlet channel 413 and the water outlet channel 414 are respectively formed by the recess on the rear side of the collection plate 41, and the bottom end of the sample outlet channel 415 is connected to the bottom end of the sample collection cavity 411.

[0249] The top of the water inlet channel 413 is also connected to an external clean water collection device. This clean water collection device can be a pipe connected to a clean water tank or water switch, or it can be a pipe directly attached to the inner wall of the toilet and located above the collector for collecting clean water. This invention does not limit the specific implementation of the clean water collection device.

[0250] The diameter of the water outlet channel 414 is much smaller than that of the water inlet channel 413, and the top of the water outlet channel 414 can be connected to the clean water transfer pipe 3012 through a pipe.

[0251] In other words, the water collected by the water collection device flows into the water collection chamber 412 from the water inlet channel 413. The water collection chamber 412 is similar to a water storage tank. The water in the water collection chamber 412 then enters the water flow channel of the flow channel plate 3 through the water outlet channel 414 and the water transfer pipe 3012.

[0252] When water enters the clean water collection chamber 412, air bubbles will be generated and float to the surface. The water outlet channel 414 is located at the bottom of the clean water collection chamber 412 and is relatively narrow, so air bubbles will not enter the water outlet channel 414. After flowing into the clean water transfer pipe 3012 from the water outlet channel 414, no air bubbles will be generated in the clean water flowing into the clean water channel.

[0253] A liquid level sensor is also installed inside the clean water collection chamber 412 to sense the liquid level of the clean water.

[0254] The rear side of the collection plate 41 is also provided with a sewage discharge channel 416, which extends to the top of the collection plate 41 and is connected to the sewage transfer pipe 3014 through a pipe. The sewage transfer pipe 3014 is connected to the detection chamber, and the inner cover plate 42 is also provided with a liquid outlet 421 connected to the sewage discharge channel 416. After the detection is completed, the mixed liquid in the detection chamber can flow into the sewage discharge channel 416 from the sewage discharge channel 302 of the flow channel plate 3 and the sewage transfer pipe 3014 in sequence, and then flow into the toilet from the sewage discharge channel 416 and the liquid outlet 421.

[0255] In another embodiment shown in Figures 28-30, the collector also includes a collection plate 41, an outer cover plate 43, an inner cover plate 42, and a clean water collection component. Similarly, the collection plate 41 is also disc-shaped and is also provided with a clean water collection chamber 412 and a sample collection chamber 411. The top surface of the collection plate 41 is also provided with a water inlet channel 413, a water outlet channel 414, and a sample outlet channel 415.

[0256] The difference is that the sample collection chamber 411 and the water collection chamber 412 are formed by assembling the collection plate 41, the inner cover plate 42 and the outer cover plate 43. The sample collection chamber 411 and the water collection chamber 412 are through slots provided on the collection plate 41. After the front cover plate and the rear cover plate are closed on the front and rear sides of the collection plate 41, the front and rear sides of the sample collection chamber 411 and the water collection chamber 412 are sealed, thus forming the sample collection chamber 411 and the water collection chamber 412.

[0257] The volume of the water collection chamber 412 is larger than that of the sample collection chamber 411. The water collection chamber 412 and the sample collection chamber 411 are respectively located on both sides of the collection plate 41, and an isolation section is provided in the middle.

[0258] The top surface of the acquisition plate 41 is provided with a sample collection groove 401, which is formed by a recess in the top surface of the acquisition plate 41.

[0259] The bottom wall of the sample collection tank 401 is also provided with a sampling channel, which is formed by the indentation of the bottom wall of the sample collection tank 401 into the sample collection cavity 411.

[0260] The sample outlet channel 415 is also formed by the recess of the bottom wall of the sample collection groove 401 into the bottom of the sample collection cavity 411. The sample outlet channel 415 is located on the isolation section, and the top of the sample outlet channel 415 is a vertically extending straight channel, while the middle area is a curved flow channel, and the bottom is a horizontally extending channel that extends to the bottom of the sample collection cavity. This curved design of the sample outlet channel 415 also allows the sample to fit against the inner wall of the sample outlet channel 415, and mixes during the flow process to reduce air bubbles.

[0261] The bottom of the sample collection chamber 411 is also provided with a drain outlet 417, which is open towards the bottom of the collection plate 41, and excess samples can flow into the toilet from the drain channel 302.

[0262] The water inlet channel 413 is also formed by the bottom wall of the sample collection tank 401 recessed into the clean water collection chamber 412, and the water inlet channel 413 is also located on the front side of the collection plate 41. A pipe can be inserted into the top of the water inlet channel 413, and the pipe communicates with the clean water collection device. Similar to the previous embodiment, it will not be described again.

[0263] The water outlet channel 414 is formed by bending upward from the bottom of the clear water collection chamber 412 to the bottom wall of the sample collection tank 401. The water outlet channel 414 is formed by the recess of the rear side of the collection plate 41 and is also located on the isolation part. The water outlet channel 414 also has a bent shape. In the process of collecting clear water, it can also reduce the number of air bubbles in the clear water entering the clear water channel of the flow channel plate 3.

[0264] The rear side of the isolation section is also provided with a sewage discharge channel 416. The top of the sewage discharge channel 416 extends to the bottom wall of the sample collection tank 401 and is connected to the sewage transfer pipe 3014 through a pipe. The bottom end of the sewage discharge channel 416 is connected to the liquid outlet 421 of the inner cover plate 42. The inner cover plate 42 covers the rear side of the collection plate 41 and is used to adhere to the inner wall of the toilet. The liquid in the detection chamber can flow into the sewage discharge channel 416 sequentially from the sewage discharge channel 302 and the sewage transfer pipe 3014, and then flow into the toilet from the liquid outlet 421.

[0265] The collector also includes two liquid level sensors, which are installed in the clean water collection chamber 412 and the sample collection chamber 411 respectively, to sense the liquid level of the clean water and the sample.

[0266] One sample flow channel can be provided on the flow channel plate 3, which can be directly connected to the sample collection cavity 411 through the sample adapter 3011. In another embodiment, two sample flow channels can also be provided on the flow channel plate 3, with the inner ends of the two sample flow channels respectively connected to two circumferential holes 32, and the outer ends respectively connected to two pipes through two sample adapters 3011.

[0267] Two sample channels are defined as the upper sample channel 341 and the lower sample channel 342, and the pipes connected to the two sample channels are the upper sample pipe 344 and the lower sample pipe 345, respectively. The upper sample channel 341 is connected to the upper sample pipe 344 through a sample transfer pipe 3011, and the lower sample channel 342 is connected to the lower sample pipe 345 through a sample transfer pipe 3011.

[0268] One end of the lower sample conduit is connected to the lower sample flow channel 342, and the other end is connected to the sample outlet channel 415 of the sample collection chamber 411. A burette is installed in the middle of the lower sample conduit, which is defined as the sample burette 343. One end of the upper sample conduit is connected to the upper sample flow channel 341, and the other end is connected to the top of the sample burette 343. When a sample needs to be extracted, the rotor 6 is first aligned with the circumferential hole 32 connected to the upper sample flow channel 341 to extract the air from the upper sample flow channel 341, the upper sample conduit, and the sample burette 343, creating a negative pressure in the sample burette 343. The sample can then drip from the sample collection chamber 411 into the sample burette 343. Then, the rotor 6 is rotated so that the transfer channel is aligned with the circumferential hole 32 of the lower sample flow channel 342, extracting the air from the lower sample flow channel 342 and the lower sample conduit, and allowing the liquid in the sample burette 343 to flow from the lower sample conduit into the lower sample flow channel 342. This setup ensures that the sample is slowly dripped into the lower sample channel 342 without generating air bubbles.

[0269] Of course, in another embodiment, an exhaust port 418 is provided in the sample collection chamber 411, the upper sample flow channel 341 can communicate with the exhaust port 418, and the lower sample flow channel 342 can communicate with the sample outlet channel 415 of the sample collection chamber 411. In this case, the sample collection chamber 411 is similar to the sample burette described above, and the operation method is the same as above, so it will not be described again.

[0270] A clear water channel can also be provided in the flow channel plate 3, which is directly connected to the clear water collection chamber 412.

[0271] Of course, the flow channel plate 3 is equipped with two clear water channels, operating on the same principle as the two sample flow channels mentioned above. The two clear water channels are the upper clear water channel 351 and the lower clear water channel 352. The outer ends of the two clear water channels are respectively connected to two circumferential holes 32. Similarly, the outer end of the lower clear water channel is connected to the clear water transfer pipe 3012, which is connected to the clear water collection chamber 412 via the upper clear water pipe. The lower clear water pipe is also equipped with a burette, which is defined as a clear water burette. The clear water burettes of the upper and lower clear water pipes are connected.

[0272] The upper clear water flow channel 351 is connected to the clear water transfer pipe 3012, which is connected to the upper end of the clear water burette through the upper clear water pipe.

[0273] When a sample needs to be extracted, the rotor 6 must first be aligned with the circumferential hole 32 connected to the upper clear water channel 351. This removes air from the upper clear water channel 351, the sample loading clear water pipe, and the clear water burette, creating negative pressure within the clear water burette. Clear water can then drip from the clear water collection chamber 412 into the clear water burette. Next, the rotor 6 is rotated so that the transfer channel is aligned with the circumferential hole 32 of the lower clear water channel 352. This removes air from the lower clear water channel 352 and the lower clear water pipe, allowing liquid from the clear water burette to flow from the lower clear water pipe into the lower clear water channel 352. This setup ensures that water drips slowly into the lower clear water channel 352 without generating air bubbles.

[0274] This invention also relates to a control method for a urine analyzer, as shown in Figures 30 and 32. The urine analyzer includes the aforementioned reagent kit, collector, rotary valve, and detection mechanism. The reagent kit also has multiple reagent chambers. The collector also has a sample collection chamber and a water collection chamber. The rotary valve, as described above, includes a microfluidic chip and a rotor. The microfluidic chip has a common flow channel, an upper sample flow channel, a lower sample flow channel, multiple reagent flow channels, a detection flow channel, and an air flow channel. The outer end of the lower sample flow channel is connected to the sample collection chamber via a lower sample conduit, which contains a sample burette. The upper sample flow channel is connected to the upper end of the sample burette via an upper sample conduit. The outer end of the common flow channel is connected to the water collection chamber via a drive conduit or other conduit. The outer ends of the multiple reagent flow channels are respectively connected to the multiple reagent chambers.

[0275] The rotor and microfluidic chip are rotatably connected and have a transfer channel. The inner end of the transfer channel is connected to the inner end of the common flow channel, and the outer end, as the rotor rotates, is connected to the upper sample flow channel, the lower sample flow channel, the multiple reagent flow channels, the detection flow channel, and the air flow channel. In other words, each time the rotary valve switches to the lower sample flow channel, the upper sample flow channel, the multiple reagent flow channels, the detection flow channel, or the air flow channel, the transfer channel is connected to these flow channels.

[0276] The testing facility is the same as the one described above, equipped with a detector and a testing chamber. The testing chamber is connected to the testing flow channel, and the detector is used to test the sample inside the testing chamber.

[0277] The control method for a urine analyzer includes the following steps:

[0278] S1: The rotary valve switches to the sample flow channel, drawing the sample from the sample collection chamber into the transfer channel. When the sample flow channel is directly connected to the sample collection chamber, the sample from the sample collection chamber can be directly drawn into the transfer channel.

[0279] S2: The rotary valve switches to the detection channel, and the transfer channel is connected to the detection channel, driving the water in the clear water collection chamber to flow into the common channel and the transfer channel, where the water in the transfer channel mixes with the sample in the transfer channel. The outer end of the common channel is connected to the clear water collection chamber, allowing water in the clear water collection chamber to be drawn from the common channel into the transfer channel and mixed with the sample in the transfer channel.

[0280] S3: The rotary valve switches to the detection channel to discharge the mixed sample and water in the transfer channel.

[0281] S4: Push the water in the common flow channel into the detection chamber for detection. Perform a comparative test first as a reference for sample detection.

[0282] S5: The rotary cutting valve switches to the sample flow channel to quantitatively extract the sample into the transfer channel.

[0283] S6: The rotary valve switches to the reagent flow channel, the transfer channel is connected to the reagent flow channel, and the reagent in the reagent chamber is quantitatively drawn into the transfer channel.

[0284] S7: The rotary valve switches to the detection channel, pushing the reagents and samples in the transfer channel into the detection chamber;

[0285] S8: The detector begins detection;

[0286] S9: Push the water in the common flow channel into the detection flow channel and discharge it from the detection chamber.

[0287] The outer end of the rotor's transfer channel connects to different flow channels as the rotary valve switches. For example, when the rotary valve switches to the reagent flow channel, the outer end of the transfer channel connects to that reagent flow channel. The same applies when the rotary valve switches to other flow channels, which will not be elaborated further.

[0288] By directly connecting the common flow channel and the clean water collection chamber, the water in the common flow channel can be directly pushed into the detection chamber or sample collection chamber for cleaning after the test, thereby improving the operating efficiency of the urine analyzer. Furthermore, with the common flow channel and clean water collection chamber directly connected, when samples and reagents need to be extracted, the common flow channel and drive pipe are first filled with clean water, and then the transfer channel is filled with air. This isolates the water in the common flow channel from the sample or reagent. After the pump starts, the clean water and a small amount of air in the transfer channel drive the movement of the reagent and sample. Since clean water is not easily compressed, it allows for more precise extraction of samples or reagents into the microfluidic chip, thus improving the accuracy of the test.

[0289] As a preferred embodiment, step S1 includes:

[0290] S1.1: The rotary valve switches to the upper sample flow channel, the transfer channel is connected to the upper sample flow channel, and the air in the upper sample flow channel and the sample burette is extracted, a negative pressure is formed in the sample burette, and the sample in the sample collection chamber flows into the sample burette;

[0291] S1.2: Switch the rotary valve to connect the transfer channel with the lower sample flow channel, and drive the sample in the sample burette to flow into the transfer channel.

[0292] First, remove the air from the sample burette to reduce the amount of air bubbles entering the transfer channel.

[0293] Optionally, the urine analyzer further includes a first pump and a second pump, wherein the first pump is a peristaltic pump and the second pump is a plunger pump. The two ends of the peristaltic pump's flexible tube are connected to two pipes respectively. One of the pipes is connected to the clear water collection chamber at one end, and the other is connected to the plunger pump at the other end. That is, the two pipes and the drive pipe are connected in series, connecting the clear water collection chamber and the common flow channel. The logic diagram of this embodiment can be seen in Figure 32. This embodiment differs from the embodiments with the peristaltic pump and plunger pump in that it does not have two drive pipes, so the peristaltic pump adapter and drive flow channel are not required. Furthermore, the common flow channel and the clear water collection chamber are directly connected in this embodiment, so an upper and lower clear water flow channel are not needed.

[0294] In step S1.1, the peristaltic pump rotates forward to extract air from the upper sample channel and the sample burette;

[0295] In step S1.2, the peristaltic pump rotates forward to draw the sample from the sample burette into the transfer channel;

[0296] In step S2, the peristaltic pump reverses and pumps the water in the clean water collection chamber into the common flow channel and the transfer channel;

[0297] In step S3: the rotary valve switches to the air channel, the transfer channel is connected to the air channel, the control module controls the plunger pump to rotate forward to draw in air, the rotary valve switches to the detection channel, and the plunger pump resets to discharge the mixed sample and water in the transfer channel from the detection channel and the detection chamber;

[0298] In step S4, the peristaltic pump reverses to divert water from the common flow channel to the detection flow channel; then the rotary valve switches to the air flow channel, the plunger pump rotates forward to draw a fixed amount of air into the transfer channel, the rotary valve switches back to the detection flow channel, and the plunger pump resets to push water from the detection flow channel into the detection chamber for detection.

[0299] In step S5, the plunger pump rotates forward to quantitatively extract the sample into the transfer channel;

[0300] In step S6, the plunger pump rotates forward and quantitatively draws the reagent from the reagent chamber into the transfer channel;

[0301] In step S7, the plunger pump is reset and pushes the reagents and samples in the transfer channel into the detection chamber;

[0302] In step S9, the rotary valve switches to the detection channel, the peristaltic pump reverses and pushes the water in the common channel into the detection channel, and discharges it from the detection chamber.

[0303] Optionally, in step S5, it is first determined whether the sample needs to be diluted;

[0304] If dilution is required, the rotary valve first switches to the detection channel, and the peristaltic pump reverses to push a measured amount of clean water into the detection channel. Then, the rotary valve switches to the air channel, and the plunger pump rotates forward to draw a measured amount of air into the transfer channel. This air is used to isolate the water in the common channel. After the rotary valve switches back to the detection channel, the plunger pump rotates forward to draw clean water from the detection channel into the transfer channel. At this time, the air separates the clean water outside the detection channel from the clean water in the transfer channel. The rotary valve then switches to the lower sample channel, and the plunger pump rotates forward to draw a measured amount of sample from the lower sample channel into the transfer channel to mix with the water in the transfer channel. Then, the rotary valve switches to the air channel, and the plunger pump rotates forward again to draw a measured amount of air into the transfer channel. This air is used to isolate the water outside the detection channel from the water and sample in the transfer channel. The rotary valve switches to the detection channel, the plunger pump resets, and pushes the diluted sample into the transfer channel.

[0305] If dilution is not required, the rotary valve switches the air flow channel, first quantitatively drawing in air, and then the rotary valve switches to the lower sample flow channel, at which point the plunger pump rotates forward and quantitatively draws in the sample into the transfer channel.

[0306] Optionally, it is determined whether multiple reagents need to be extracted. If only one reagent needs to be extracted, step S7 is performed after step S6; if multiple reagents need to be extracted, step S6 is repeated multiple times. The rotary valve is switched to different reagent channels as needed to extract different reagents into the transfer channel. Some testing items require mixing of multiple reagents, so step S6 needs to be repeated to extract different reagents into the transfer channel.

[0307] It should be understood that whether the test item needs to be diluted, the amount of diluted sample required for the test, and the type and amount of reagents required are all set in the control module. Therefore, after the test is started, the control module will determine the process to be carried out based on the test item.

[0308] As a preferred embodiment, the rotary valve is provided with a mixing chamber, which is located on the path of the detection channel and communicates with the detection channel.

[0309] In step S8, after the rotary valve switches to the detection channel, the plunger pump resets and pushes the reagents and samples in the transfer channel into the mixing chamber to mix into a homogenized liquid. The plunger pump then pushes the homogenized liquid into the detection chamber.

[0310] Further, in step S8, the plunger pump rotates forward for a preset time, and then resets for a preset time. After the reagent and sample in the mixing chamber are mixed into the mixed liquid, the plunger pump pushes the mixed liquid into the detection chamber.

[0311] Furthermore, the mixing cavity includes a mixing bend and a mixing chamber that are interconnected, wherein the mixing bend is a curved flow channel.

[0312] The plunger pump rotates forward for a preset time, then resets for a preset time. After the reagent and sample are continuously mixed into a homogeneous liquid by flowing through the mixing bend and the mixing chamber, the plunger pump resets and pushes the homogeneous liquid into the detection chamber.

[0313] Optionally, in step S8, after the plunger pump resets and pushes the reagents and samples in the transfer channel into the mixing chamber to form the mixed liquid, the rotary valve switches to the air channel, the plunger pump rotates forward and quantitatively draws air into the transfer channel, and then the rotary valve switches back to the detection channel, the plunger pump resets and pushes the mixed liquid in the mixing chamber into the detection chamber. If the plunger pump stroke is insufficient, a quantitative amount of air needs to be drawn into the mixed liquid in the mixing chamber and then into the detection chamber.

[0314] Optionally, in step S9, the peristaltic pump reverses to push the water in the common channel into the detection channel, where it combines with the sample and reagents in the detection chamber to form waste liquid. The rotary valve switches to the air channel, and the plunger pump rotates forward to draw air into the transfer channel. Then, the rotary valve switches back to the detection channel, the plunger pump resets, and the waste liquid in the detection chamber is discharged. After the detection is completed, the water in the common channel is directly pushed into the detection chamber to discharge the waste liquid.

[0315] Optionally, after step S9, step S10 is also included: the peristaltic pump reverses to push the water in the common flow channel into the detection flow channel and discharge it from the detection chamber.

[0316] Then, the rotary valve switches to the lower sample flow channel, and the peristaltic pump reverses to push the water in the common flow channel from the lower sample flow channel into the sample collection chamber, and then discharges it from the sample collection chamber. Water from the common flow channel is pushed into the sample collection chamber and the detection chamber. The detection chamber is connected to the collector's drain channel, so waste liquid is discharged from the collection chamber.

[0317] The order of steps S10 can also be changed. The rotary valve can be switched to the lower sample flow channel first, and the peristaltic pump reverses to push the water in the common flow channel from the lower sample flow channel into the sample collection chamber and then discharge it from the sample collection chamber.

[0318] The peristaltic pump reverses to push the water in the common flow channel into the detection flow channel and then discharges it from the detection chamber.

[0319] Optionally, after step S10, step S11 is also included: the rotary valve switches to the detection channel, and the peristaltic pump reverses to push all the remaining water in the common channel into the detection channel and discharge it from the detection chamber.

[0320] As a preferred embodiment, a first sensor is provided inside the sample burette;

[0321] The urine analyzer also includes a control module, which is connected to the peristaltic pump, the plunger pump, the rotary valve, and the first sensor.

[0322] Before step S2, the process also includes the following steps: the first sensor sends the sample volume information sensed in the sample burette to the control module. If the sample volume information does not meet the requirements, the process ends; if it meets the requirements, step S2 is performed.

[0323] In step S8, the detector sends the detection result to the control module after detection. After step S9, if the detection result is abnormal, the control module restarts steps S1 to S9; if the detection result is normal, the next detection item is performed.

[0324] The urine analyzer also includes a warning light, which is connected to the control module. After step S9, if two consecutive test results are abnormal, the control module will activate the warning light.

[0325] Preferably, a second sensor is installed inside the clean water collection chamber, and the second sensor is also connected to a control module. Before step S3, the procedure further includes the following step: the second sensor sends the detected amount of clean water in the clean water collection chamber to the control module. If the amount does not meet the requirements, the control module controls the process to end; if the amount meets the requirements, then step S4 is performed.

[0326] After the urine analyzer has been running for several months or after a set number of runs, the reagent kit needs to be replaced. Before replacing the reagent kit, the reagent flow path needs to be cleaned. The specific steps are as follows:

[0327] S01: The rotary valve switches to the detection channel, and the peristaltic pump reverses to push the water in the clean water collection chamber into the transfer channel and the detection channel sequentially from the common channel.

[0328] S02: The rotary valve switches to the air flow channel, and the plunger pump or the peristaltic pump rotates forward to draw air into the transfer channel;

[0329] S03: The rotary valve switches to the washing channel, and the plunger pump rotates forward to draw a metered amount of washing liquid into the transfer channel;

[0330] S04: The rotary valve switches to the detection channel again, the plunger pump resets and pushes the washing liquid in the transfer channel into the detection channel, and mixes it with the water in the detection channel to form a diluted washing liquid. Then the peristaltic pump reverses and draws the diluted washing liquid in the detection channel into the transfer channel.

[0331] S05: The rotary valve switches to one of the reagent channels, and the peristaltic pump reverses to push the diluted washing solution in the transfer channel into the reagent channel and the reagent chamber; the rotary valve switches multiple reagent channels in sequence, and the peristaltic pump pushes the diluted washing solution in the transfer fluid into multiple reagent chambers in sequence;

[0332] S06: The rotary valve switches sequentially to multiple reagent channels, and the peristaltic pump reverses sequentially to push the clean water in the common channel into multiple reagent channels and multiple reagent chambers;

[0333] S07: Replace with a new reagent kit.

[0334] As a preferred embodiment, in step S01: the rotary valve switches to the detection channel, and the peristaltic pump reverses to push the water in the clean water collection chamber into the transfer channel and the mixing chamber sequentially from the common channel;

[0335] Step S04: The rotary valve switches to the detection channel again, the plunger pump resets and pushes the washing liquid in the transfer channel into the detection channel and then into the mixing chamber. The peristaltic pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid. Then the peristaltic pump reverses to pump the diluted washing liquid in the detection channel into the transfer channel.

[0336] The detergent and water are mixed in the mixing chamber before being pushed into multiple reagent channels and reagent chambers.

[0337] Optionally, the urine analyzer needs to be cleaned regularly after several months or a preset number of operations, including the following steps:

[0338] S001: The rotary valve switches to the detection channel, and the peristaltic pump reverses to push the water in the clean water collection chamber into the transfer channel and the detection channel sequentially from the common channel.

[0339] S002: The rotary valve switches to the air flow channel, and the plunger pump or the peristaltic pump rotates forward to draw air into the transfer channel;

[0340] S003: The rotary valve switches to the washing channel, and the plunger pump rotates forward to draw a metered amount of washing liquid into the transfer channel;

[0341] S004: The rotary valve switches to the detection channel again, the plunger pump resets and pushes the washing liquid in the transfer channel into the detection channel, and mixes it with the water in the detection channel to form a diluted washing liquid;

[0342] S005: The peristaltic pump reverses to draw the diluted washing solution in the detection channel into the transfer channel;

[0343] S005: The rotary cutting valve switches to the lower sample flow channel, and the peristaltic pump reverses to push the diluent washing solution in the transfer channel into the sample collection chamber;

[0344] S006: Repeat steps S001 to S004, the peristaltic pump reverses to push the diluted washing liquid in the detection channel into the detection chamber;

[0345] S007: Wait for the preset time;

[0346] The rotary valve first switches to the lower sample flow channel, the peristaltic pump reverses to push the water in the common flow channel into the sample collection chamber and then discharges it; then the rotary valve switches to the detection flow channel, the peristaltic pump reverses to push the water in the common flow channel into the detection chamber and then discharges it; or

[0347] After waiting for a preset time, the rotary valve switches to the detection channel, the peristaltic pump reverses to push the water in the common channel into the detection chamber and then discharges it. Then the rotary valve switches to the lower sample channel, the peristaltic pump reverses to push the water in the common channel into the sample collection chamber and then discharges it.

[0348] The cleaning process involves immersing the diluted washing solution in multiple channels, sample collection chambers, and detection chambers to increase the cleaning reaction time and cleaning power.

[0349] As a preferred embodiment, the diluted washing solution needs to be mixed again in the mixing chamber. That is, in step S001: the rotary valve switches to the detection channel, and the peristaltic pump reverses to push the water in the clean water collection chamber into the transfer channel and the mixing chamber from the common channel.

[0350] Step S004: The rotary valve switches to the detection channel again, the plunger pump resets and pushes the washing liquid in the transfer channel into the mixing chamber, the peristaltic pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid, and then the peristaltic pump reverses to pump the diluted washing liquid in the detection channel into the transfer channel.

[0351] The control module is also connected to the peristaltic pump 91, the plunger pump 92, and the motor. It can control the operation of these components based on information from the level sensors in the sample collection chamber 411 and the clean water collection chamber 412. For example, after receiving a signal from the level sensor in the sample collection chamber 411, the control module can drive the motor to rotate the rotor 6, aligning the outer end 62 of the transfer channel with the circumferential hole 32 that communicates with the sample flow channel.

[0352] This invention also relates to a method of using a microfluidic chip, as shown in FIG31. The flow channel plate 3 is provided with the aforementioned sample flow channel, reagent flow channel 37, detection flow channel 38, and common flow channel 33. The common flow channel 33 is operably connected to the sample flow channel, reagent flow channel 37, and detection flow channel 38. A mixing chamber 39 is located on the path of the detection flow channel 38 and has an outlet and an inlet. The mixing chamber 39 includes a mixing bend 392 and a mixing chamber 391. The mixing bend 392 is a curved flow channel located on the path of the detection flow channel 38. The width of the mixing chamber 391 is larger than the diameter of the detection flow channel 38.

[0353] The method of using flow channel plate 3 includes the following steps:

[0354] S11, Drive the sample in the sample flow channel into the common flow channel 33;

[0355] S12, drive the reagent in the reagent flow channel 37 into the common flow channel 33;

[0356] S13. The sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing chamber 39 from the detection flow channel 38. After entering the mixing bend 392 from the inlet of the mixing chamber 39, they flow into the mixing chamber 391 to form a mixed liquid. Then the mixed liquid is driven to flow back into the detection flow channel 38 from the outlet of the mixing chamber 39 and out of the detection flow channel 38.

[0357] The sample flow channel is connected to the sample collection chamber, the reagent flow channel 37 is connected to the reagent chamber 21 containing the reagent, and the detection flow channel 38 is connected to the detection chamber.

[0358] The common flow channel 33 can be connected to the sample flow channel, reagent flow channel 37 or detection flow channel 38 through a three-way valve or other valves. The air in the common flow channel 33 can be extracted by the peristaltic pump 91 or plunger pump 92 to form a negative pressure, and then the sample in the sample flow channel or the reagent in the reagent flow channel 37 can be driven into the common flow channel 33.

[0359] Optionally, the mixing chamber 391 is located above the mixing bend 392, and the inlet of the mixing chamber 39 is below the outlet of the mixing chamber 39.

[0360] In step S13, the sample and reagent in the common flow channel 33 are driven from the detection flow channel 38 into the inlet of the mixing chamber 39. After entering the mixing bend 392 from the inlet of the mixing chamber 39, they flow into the mixing chamber 391. Then, the mixed liquid flows back from the mixing chamber 39 into the mixing bend 392, and the sample and reagent flow back due to gravity. The mixing bend 392 is then driven to flow into the mixing chamber 39. Finally, the mixed liquid is driven to re-enter the detection flow channel 38 from the mixing chamber 39 and flow out from the detection flow channel 38.

[0361] Optionally, the mixing chamber 391 is located above the mixing bend 392; in step S3, the sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing chamber 39 from the detection flow channel 38, and then flow into the mixing chamber 391 after entering the mixing bend 392 from the inlet of the mixing chamber 39. Then the mixing liquid flows back from the mixing chamber 391 into the mixing bend 392. After staying for 1-2 seconds, the mixing bend 392 is driven to flow into the mixing chamber 391 from the mixing bend 392. Finally, the mixing liquid is driven to re-enter the detection flow channel 38 from the mixing chamber 391 and flow out from the detection flow channel 38.

[0362] Pausing for 1-2 seconds during the mixing process of samples and reagents can improve the mixing effect.

[0363] As a preferred embodiment, the mixing chamber 39 includes a plurality of mixing bends 392 and a plurality of mixing chambers 391, which are arranged at intervals and connected to each other.

[0364] In step S13, the sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing chamber 39 from the detection flow channel 38, and then enter multiple mixing bends 392 and multiple mixing chambers 39 from the inlet of the mixing chamber 39. Finally, the mixed liquid is driven to flow out from the detection flow channel 38.

[0365] Furthermore, the mixing bend 392 is an S-shaped bend and includes at least two horizontal flow channels and at least one turning flow channel 394, with any one turning flow channel 394 located at both ends of the two horizontal flow channels;

[0366] The horizontal flow channel extends in the horizontal direction, and the turning flow channel 394 includes a curved inner arc 395 and an outer arc 396. Both the inner arc 395 and the outer arc 396 are arc-shaped, and the inner diameter of the inner arc 395 is smaller than the inner diameter of the outer arc 396.

[0367] Optionally, the inner wall of the mixing chamber 391 includes a first arc surface 397 and a second arc surface 398 opposite to the first arc surface 397, wherein the first arc surface 397 and the second arc surface 398 are arc surfaces protruding outward.

[0368] Optionally, each mixing chamber 391 is connected to the horizontal flow channels of two mixing bends 392, and the two horizontal flow channels are arranged radially symmetrically at the top and bottom of the mixing chamber 391.

[0369] In step S13, the sample and reagent in the common flow channel 33 are driven to enter the inlet of the mixing chamber 39 from the detection flow channel 38. After entering a mixing bend 392 from the inlet of the mixing chamber 39, they flow into the mixing chamber 391. Then, they flow from the mixing chamber 39 into another mixing bend 392 to form a mixed liquid. After staying for 1-2 seconds, the mixed liquid flows back into the mixing chamber 391 and is driven to be discharged from the mixing bend 392.

[0370] In one embodiment, each mixing chamber has an inlet and an outlet, the inlet and outlet of each mixing chamber are connected to the adjacent mixing bend, and the inlet of each mixing chamber is located above the outlet.

[0371] In step S13, after the sample and reagent enter the mixing chamber, they flow from one of the mixing bends through an adjacent inlet into the mixing chamber, and then flow from the outlet into another mixing bend. The sample and reagent continuously flow in the multiple mixing chambers and multiple mixing bends to form the mixed liquid.

[0372] Microfluidic chips can be placed vertically, meaning that when samples and reagents flow from bottom to top, there is no need to consider the effects of gravity, thus preventing residue problems in the mixing chamber.

[0373] Optionally, the flow channel plate 3 is also provided with a clear water flow channel, and the common flow channel 33 can be connected to the clear water flow channel through the transfer channel of the rotor 6;

[0374] After step S13, step S14 is also included: driving the water in the clear water channel into the common channel 33, then driving the water in the common channel 33 into the detection channel 38, then entering the mixing chamber 39 from the inlet of the mixing chamber 39, and then entering the detection channel 38 again from the outlet of the mixing chamber 39, and being discharged from the detection channel 38.

[0375] As a preferred embodiment, the flow channel plate 3 also has a central hole 31 and a plurality of circumferential holes 32 arranged around the central hole 31. The central hole 31 penetrates the flow channel plate 3 and communicates with the inner end of the common flow channel 33. The plurality of circumferential holes 32 are arranged in a circumferential direction with the central hole 31 as the center. The inner end of the common flow channel 33 communicates with the central hole 31, and the outer end is connected to the pump through a drive pipe. The inner end of the sample flow channel communicates with one circumferential hole 32. The inner end of the reagent flow channel 37 communicates with one circumferential hole 32. The inner end of the detection flow channel 38 communicates with one circumferential hole 32.

[0376] The central hole 31 is connected to the inner end of the transfer channel of a rotor 6, and the outer end of the transfer channel can be connected to any circumferential hole 32 as the rotor 6 rotates.

[0377] In step S11, the rotor 6 rotates, and the transfer channel is connected to the sample flow channel through one of the circumferential holes 32. The pump extracts the air from the common flow channel 33 and the sample flow channel, and pumps the sample from the sample flow channel into the common flow channel 33.

[0378] In step S12, the rotor 6 rotates, and the transfer channel is connected to the reagent flow channel 37 through one of the circumferential holes 32. The pump extracts the air from the common flow channel 33 and the reagent flow channel 37, and draws the sample from the reagent flow channel 37 into the common flow channel 33.

[0379] In step S13, the rotor 6 rotates, and the transfer channel is connected to the detection channel 38 through one of the circumferential holes 32; the pump drives the sample and reagent in the common channel 33 to enter the inlet of the mixing chamber 39 from the detection channel 38, and after entering the mixing bend 392 from the inlet of the mixing chamber 39, they flow into the mixing chamber 391 to form a mixed liquid. Then, the mixed liquid is driven to flow back into the detection channel 38 from the outlet of the mixing chamber 39 and out of the detection channel 38.

[0380] As another preferred embodiment, the flow channel plate 3 has two sample flow channels, namely an upper sample flow channel 341 and a lower sample flow channel 342. The inner ends of the lower sample flow channel 342 and the upper sample flow channel 341 are respectively connected to two circumferential holes 32. The lower sample flow is connected to the sample collection chamber containing the sample through the lower sample pipe, and a sample burette is provided on the lower sample pipe. The upper sample flow channel 341 is connected to the sample burette through the upper sample pipe;

[0381] In step S11, the rotor 6 rotates, aligning the outer end 62 of the transfer channel with the circumferential hole 32 that is connected to the upper sample flow channel 341. The pump, in conjunction with the drive pipe, extracts the air from the common flow channel 33, the transfer channel, the upper sample flow channel 341, and the sample burette.

[0382] Then the rotor 6 rotates and aligns the outer end 62 of the transfer channel with the circumferential hole 32 that is connected to the lower sample flow channel 342, and draws the sample in the sample collection cavity from the lower sample flow channel 342 to the common flow channel 33.

[0383] Setting up a sample burette can reduce the amount of air bubbles flowing into the sample flow channel from the sample collection chamber.

[0384] Optionally, the flow channel plate 3 is also provided with a clear water flow channel, which is connected to a circumferential hole 32.

[0385] After step S13, step S14 is also included: the rotor 6 rotates, the transfer channel is connected to the clear water channel through one of the circumferential holes 32, the pump drives the water in the clear water channel to enter the common channel 33, and then drives the water in the common channel 33 to enter the detection channel 38, and then enters the mixing chamber 39 from the inlet of the mixing chamber 39, and then enters the detection channel 38 again from the outlet of the mixing chamber 39, and is discharged from the detection channel 38.

[0386] Preferably, the flow channel plate 3 is provided with an upper clear water flow channel 351 and a lower clear water flow channel 352. The inner ends of the upper clear water flow channel 351 and the lower clear water flow channel 352 are respectively connected to two circumferential holes 32. The lower clear water flows through a lower clear water pipe and is connected to a clear water collection chamber, and a clear water burette is provided on the lower clear water pipe. The upper clear water flow channel 351 is connected to the clear water burette through the upper clear water pipe.

[0387] After step S13, step S14 is also included: the rotor 6 rotates, aligning the outer end 62 of the transfer channel with the circumferential hole 32 that is connected to the upper clear water flow channel 351, and the pump draws the air in the common flow channel 33, the transfer channel, the upper clear water flow channel 351, and the clear water burette to the outside.

[0388] Then the rotor 6 rotates, aligning the outer end 62 of the transfer channel with the circumferential hole 32 that connects to the lower clear water channel 352, and drawing the sample in the sample collection chamber from the lower clear water channel 352 to the common channel 33. The rotor 6 rotates, aligning the common channel 33 with the circumferential hole 32 of the detection channel 38, and the water in the common channel 33 is sequentially detected in the detection channel 38 and discharged from the detection channel 38.

[0389] Optionally, the flow channel plate 3 is also provided with an air flow channel 36, the inner end of which is connected to another circumferential hole 32.

[0390] In step S3, before the rotor 6 rotates and the transfer channel connects to the detection channel 38 through one of the circumferential holes 32; the rotor 6 rotates so that the transfer channel is aligned with the circumferential hole 32 that is connected to the air, so that the common channel 33 is connected to the air channel 36, and the pump draws air from the air channel 36 into the common channel 33.

[0391] Then the rotor 6 rotates, and the transfer channel is connected to the detection channel 38 through one of the circumferential holes 32; the pump drives the sample and reagent in the common channel 33 to enter the inlet of the mixing chamber 39 from the detection channel 38, and after entering the mixing bend 392 from the inlet of the mixing chamber 39, it flows into the mixing chamber 391 to form a mixed liquid, and then drives the mixed liquid to flow back into the detection channel 38 from the outlet of the mixing chamber 39, and then out of the detection channel 38.

[0392] The flow channel plate 3 of the present invention can also be adapted to other urine analyzers 100, and equipped with the above-mentioned pump or rotor 6, so that the sample and reagent can be mixed in the flow channel plate 3, reducing air bubbles and increasing the accuracy of detection.

[0393] The preferred embodiments of the present invention have been described in detail above, but it should be understood that, if necessary, aspects of the embodiments can be modified to utilize aspects, features, and concepts from various patents, applications, and publications to provide other embodiments.

[0394] In light of the detailed description above, these and other changes can be made to the embodiments. Generally, the terminology used in the claims should not be considered limited to the specific embodiments disclosed in the specification and claims, but should be understood to include all possible embodiments together with the full scope of equivalents enjoyed by these claims.

[0395] Those skilled in the art will understand that the above embodiments are specific examples of implementing the present invention, and in practical applications, various changes in form and detail may be made without departing from the spirit and scope of the present invention.

Claims

1. A urine analyzer, characterized in that, The urine analyzer includes: A reagent kit, wherein the reagent kit has multiple reagent chambers, and reagents are placed in the reagent chambers; The collector is equipped with a sample collection chamber and a water collection chamber; A rotary valve is provided with a common flow channel, a sample flow channel, multiple reagent flow channels, a detection flow channel, an air flow channel, and a transfer channel; the sample flow channel is connected to the sample collection chamber via a lower sample pipe; the common flow channel is connected to the water collection chamber; the multiple reagent flow channels are respectively connected to multiple reagent chambers; one end of the transfer channel is connected to the inner end of the common flow channel, and the other end is operably connected to the sample flow channel, the multiple reagent flow channels, the detection flow channel, and the air flow channel; The detection mechanism includes a detector and a detection chamber, the detection chamber being connected to the detection flow channel.

2. A control method for a urine analyzer, characterized in that, The method applied to the urine analyzer of claim 1 includes the following steps: S1: The rotary valve switches to the sample flow channel, drawing the sample from the sample collection chamber into the transfer channel; S2: The rotary valve switches to the detection channel, the transfer channel is connected to the detection channel, and the water in the clear water collection chamber is driven to flow into the common channel and the transfer channel, and the water in the transfer channel and the sample in the transfer channel are mixed; S3: The rotary valve switches to the detection channel to drain the mixed sample and water in the transfer channel; S4: Push the water in the common flow channel into the detection chamber for detection; S5: The rotary cutting valve switches to the sample flow channel to quantitatively extract the sample into the transfer channel; S6: The rotary valve switches to the reagent flow channel, the transfer channel is connected to the reagent flow channel, and the reagent in the reagent chamber is quantitatively drawn into the transfer channel; S7: The rotary valve switches to the detection channel, pushing the reagents and samples in the transfer channel into the detection chamber; S8: The detector begins detection; S9: Push the water in the common flow channel into the detection flow channel and discharge it from the detection chamber.

3. The control method for the urine analyzer according to claim 2, characterized in that, The sample flow channel includes: The lower sample flow channel, which is connected to the sample collection chamber via a lower sample conduit and is equipped with a sample burette; and Upper sample flow channel, wherein the upper sample flow channel is connected to the sample burette; Step S1 includes: S1.1: The rotary valve switches to the upper sample flow channel, the transfer channel is connected to the upper sample flow channel, and the air in the upper sample flow channel and the sample burette is extracted, a negative pressure is formed in the sample burette, and the sample in the sample collection chamber flows into the sample burette; S1.2: Switch the rotary valve to connect the transfer channel with the lower sample flow channel, and drive the sample in the sample burette to flow into the transfer channel.

4. The control method for the urine analyzer according to claim 3, characterized in that, The urine analyzer also includes: A first pump, the first pump being connected to two pipes, one of which is connected to the clean water collection chamber; and A second pump is connected to another pipe and a drive pipe, the drive pipe being in communication with the common flow channel; In step S1.1, the first pump is started to extract air from the upper sample flow channel and the sample burette; In step S1.2, the first pump is started, drawing the sample from the sample burette into the transfer channel; In step S2, the first pump is started to pump the water in the clean water collection chamber into the common flow channel and the transfer channel; In step S3: the rotary valve switches to the air channel, the transfer channel is connected to the air channel, after the control module controls the second pump to start drawing air, the rotary valve switches to the detection channel, the second pump starts, and the mixed sample and water in the transfer channel are discharged from the detection channel and the detection chamber; In step S4, the first pump is started to push the water in the common flow channel into the detection flow channel; then the rotary valve is switched to the air flow channel, the second pump is started and draws a certain amount of air into the transfer channel, the rotary valve is switched to the detection flow channel again, the second pump is started to push the water in the detection flow channel into the detection chamber for detection; In step S5, the second pump is started to quantitatively extract the sample into the transfer channel; In step S6, the second pump is started and quantitatively draws the reagent from the reagent chamber into the transfer channel; In step S7, the second pump is activated and pushes the reagents and samples in the transfer channel into the detection chamber; In step S9, the rotary valve switches to the detection channel, the first pump starts and pushes the water in the common channel into the detection channel, and then discharges it from the detection chamber.

5. The control method for the urine analyzer according to claim 4, characterized in that, In step S5, first determine whether the sample needs to be diluted; If dilution is required, the rotary valve first switches to the detection channel, the first pump starts, and a measured amount of clean water is pushed into the detection channel; then the rotary valve switches to the air channel, the second pump starts and draws a measured amount of air into the transfer channel; after the rotary valve switches back to the detection channel, the second pump starts and draws the clean water in the detection channel into the transfer channel; the rotary valve then switches to the lower sample channel, the second pump starts, and a measured amount of sample is drawn from the lower sample channel and mixed with the water in the transfer channel. Then the rotary valve switches to the air flow channel, and the second pump starts again to draw a quantitative amount of air into the transfer channel; the rotary valve switches to the detection flow channel, and the second pump starts and pushes the diluted sample into the transfer channel; The second pump starts and draws a quantitative amount of diluted sample from the detection channel into the transfer channel. Then, the rotary valve switches back to the air channel and draws a quantitative amount of air into the transfer channel again. The rotary valve switches back to the detection channel, and the second pump starts and pushes the air drawn in the transfer channel into the detection channel. If dilution is not required, the rotary valve switches the air flow channel, first quantitatively drawing in air, and then the rotary valve switches to the lower sample flow channel, at which point the second pump starts and quantitatively draws in the sample into the transfer channel.

6. The control method for the urine analyzer according to claim 4, characterized in that, Determine whether multiple reagents need to be extracted. If only one reagent needs to be extracted, proceed to step S7 after step S6. If multiple reagents need to be extracted, repeat step S6 multiple times. After each reagent extraction, switch the rotary valve to the detection channel, push the reagent into the detection channel, and then switch the rotary valve to a different reagent channel to extract the reagent again.

7. The control method for the urine analyzer according to claim 4, characterized in that, The rotary valve is provided with a mixing chamber, which is located on the path of the detection channel and communicates with the detection channel; In step S8, after the rotary valve is switched to the detection channel, the second pump is started, pushing the reagents and samples in the transfer channel into the mixing chamber to mix into a homogenized liquid. Then, the second pump is started again to push the homogenized liquid into the detection chamber.

8. The control method for a urine analyzer according to claim 7, characterized in that, In step S8, the second pump starts for a preset time and then resets the preset time. After mixing the reagent and sample in the mixing chamber into the mixed liquid, the second pump pushes the mixed liquid into the detection chamber.

9. The control method for a urine analyzer according to claim 8, characterized in that, The mixing chamber includes a mixing bend that is connected to each other and at least one mixing chamber, wherein the mixing bend is a curved flow channel. In step S8, the second pump starts for a preset time and then resets the preset time. After the reagent and sample are continuously mixed into a homogenized liquid by flowing through the mixing bend and the mixing chamber, the second pump resets and pushes the homogenized liquid into the detection chamber.

10. The control method for a urine analyzer according to claim 9, characterized in that, In step S8, the second pump is reset, and after the reagents and samples in the transfer channel are pushed into the mixing chamber to mix into the mixed liquid, the rotary valve is switched to the air channel, the second pump is started and quantitatively draws air into the transfer channel, and then the rotary valve is switched to the detection channel again, and the second pump is reset to push the mixed liquid in the mixing chamber into the detection chamber.

11. The control method for a urine analyzer according to claim 10, characterized in that, In step S9, the first pump starts and pushes the water in the common flow channel into the detection flow channel, where it mixes with the sample and reagents in the detection chamber to form waste liquid; the rotary valve switches to the air flow channel, the second pump starts and draws air into the transfer channel, then the rotary valve switches back to the detection flow channel, the second pump resets and discharges the waste liquid from the detection chamber.

12. The control method for a urine analyzer according to claim 10, characterized in that, After step S9, step S10 is also included: the first pump is started, pushing the water in the common flow channel into the detection flow channel and discharging it from the detection chamber; Then the rotary valve switches to the lower sample flow channel, the first pump starts, and pushes the water in the common flow channel from the lower sample flow channel into the sample collection chamber, and then discharges it from the sample collection chamber; or After step S9, step S10 is also included: the rotary valve switches to the lower sample flow channel, the first pump starts, and pushes the water in the common flow channel from the lower sample flow channel into the sample collection chamber and discharges from the sample collection chamber; The first pump starts, pushing the water in the common flow channel into the detection flow channel and then discharging it from the detection chamber.

13. The control method for a urine analyzer according to claim 12, characterized in that, After step S10, step S11 is also included: the rotary valve switches to the detection channel, the first pump starts, pushes all the remaining water in the common channel into the detection channel, and discharges it from the detection chamber.

14. The control method for a urine analyzer according to claim 4, characterized in that, The sample burette is equipped with a first sensor; The urine analyzer also includes a control module, which is connected to the first pump, the second pump, the rotary valve, and the first sensor. Before step S2, the process also includes the following steps: the first sensor sends the sample volume information sensed in the sample burette to the control module. If the sample volume information does not meet the requirements, the process ends; if it meets the requirements, step S2 is executed. In step S8, the detector sends the detection result to the control module after detection.

15. The control method for a urine analyzer according to claim 14, characterized in that, If the test result is abnormal after step S9, repeat steps S1 to S9; if the test result is normal, proceed to the next test item.

16. The control method for a urine analyzer according to claim 14, characterized in that, The urine analyzer also includes a warning light, which is electrically connected to the control module. After step S9, if two consecutive detection results are abnormal, the control module will control the indicator light to issue a warning.

17. The control method for a urine analyzer according to claim 14, characterized in that, The clean water collection chamber is equipped with a second sensor connected to the control module; Before step S3, there is also a step: the second sensor will send the detected amount of clean water in the clean water collection chamber to the control module. If the amount does not meet the requirements, the control module will control the end of the process. If the requirements are met, proceed to step S4.

18. The control method for a urine analyzer according to claim 4, characterized in that, The rotary valve is also equipped with a washing flow channel; The urine analyzer also includes a washing solution and a washing chamber for holding the washing solution; After steps S1 to S9 have been cycled a preset number of times, the reagent kit needs to be replaced. The process also includes the following steps: S01: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the detection channel sequentially from the common channel; S02: The rotary valve switches to the air flow channel, the second pump or the first pump starts, and draws air into the transfer channel; S03: The rotary valve switches to the washing channel, the second pump starts, and draws a quantitative amount of washing liquid into the transfer channel; S04: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the detection channel and mixes it with the water in the detection channel to form a diluted washing liquid. Then the first pump starts and draws the diluted washing liquid in the detection channel into the transfer channel. S05: The rotary valve switches to one of the reagent channels, the first pump starts, and pushes the diluted washing solution in the transfer channel into the reagent channel and the reagent chamber; the rotary valve switches multiple reagent channels in sequence, the first pump starts, and pushes the diluted washing solution in the transfer fluid into multiple reagent chambers in sequence; S06: The rotary valve switches to multiple reagent channels in sequence, the first pump starts, and pushes the clean water in the common channel into multiple reagent channels and multiple reagent chambers in sequence; S07: Replace with a new reagent kit.

19. The control method for a urine analyzer according to claim 18, characterized in that, The rotary valve is provided with a mixing chamber, which is located on the path of the detection channel and communicates with the detection channel; Step S01: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the mixing chamber sequentially from the common channel; Step S04: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the detection channel and then into the mixing chamber. The first pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid. Then the first pump starts to draw the diluted washing liquid in the detection channel into the transfer channel.

20. The control method for a urine analyzer according to claim 4, characterized in that, The rotary valve is also equipped with a washing flow channel; The urine analyzer also includes a washing solution and a washing chamber for holding the washing solution; After steps S1 to S9 have been cycled a preset number of times, the urine analyzer is periodically cleaned, including the following steps: S001: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the detection channel sequentially from the common channel; S002: The rotary valve switches to the air flow channel, the second pump or the first pump starts, and draws air into the transfer channel; S003: The rotary valve switches to the washing channel, the second pump starts, and draws a quantitative amount of washing liquid into the transfer channel; S004: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the detection channel, and mixes it with the water in the detection channel to form a diluted washing liquid; S005: The first pump starts and draws the diluted washing solution in the detection channel into the transfer channel; S005: The rotary cutting valve switches to the lower sample flow channel, the first pump starts, and pushes the diluent washing solution in the transfer channel into the sample collection chamber; S006: Repeat steps S001 to S004, the first pump is started, and the diluted washing liquid in the detection channel is pushed into the detection chamber; S007: After waiting for a preset time, the rotary valve first switches to the lower sample flow channel, the first pump starts, and pushes the water in the common flow channel into the sample collection chamber and then discharges it. Then the rotary valve switches to the detection flow channel, the first pump starts, and pushes the water in the common flow channel into the detection chamber and then discharges it. or After waiting for a preset time, the rotary valve switches to the detection channel, the first pump starts, and pushes the water in the common channel into the detection chamber and then discharges it. Then, the rotary valve switches to the lower sample channel, the first pump starts, and pushes the water in the common channel into the sample collection chamber and then discharges it.

21. The control method for a urine analyzer according to claim 20, characterized in that, The rotary valve is provided with a mixing chamber, which is located on the path of the detection channel and communicates with the detection channel; Step S001: The rotary valve switches to the detection channel, the first pump starts, and pushes the water in the clean water collection chamber into the transfer channel and the mixing chamber sequentially from the common channel; Step S004: The rotary valve switches to the detection channel again, the second pump resets and pushes the washing liquid in the transfer channel into the mixing chamber, the first pump rotates forward for a preset time and then reverses for a preset time to mix the washing liquid and water in the mixing chamber into the diluted washing liquid, and then the first pump starts and draws the diluted washing liquid in the detection channel into the transfer channel.

22. The control method for a urine analyzer according to claim 4, characterized in that, The rotary cutting valve includes: A microfluidic chip, comprising the common channel, the lower sample channel, the upper sample channel, the water channel, multiple reagent channels, the detection channel, and the air channel; and The rotor is rotatably connected to the microfluidic chip and has the transfer channel. The inner end of the transfer channel is connected to the common channel, and the outer end rotates with the rotor and is connected to the lower sample channel, the upper sample channel, the water channel, multiple reagent channels, the detection channel and the air channel.

23. The control method for a urine analyzer according to claim 22, characterized in that, The microfluidic chip includes: The flow channel plate has the following features on its front side: A central hole, which penetrates the flow channel plate and communicates with the inner end of the common flow channel; and Multiple circumferential holes, the multiple circumferential holes being arranged around the central hole; and A sealing plate, the sealing plate being stacked between the front side of the flow channel plate and the rear side of the reagent kit; The lower sample channel, the upper sample channel, the clear water channel, the plurality of reagent channels, the detection channel, and the air channel are respectively connected to the plurality of circumferential holes.

24. The control method for a urine analyzer according to claim 22, characterized in that, The urine analyzer also includes a housing. The outer casing includes a detachable first casing and a second casing; The detection mechanism includes a detection plate, and the detection plate is provided with the detection cavity; The reagent kit, the microfluidic chip, and the detection plate are located inside the first housing. The first pump, the second pump, the rotor, and the detector are located inside the second housing.

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