Composition comprising microfibrous cellulose and acidic polysaccharide and home and personal care formulation comprising the same

Abstract

The present invention relates to a composition comprising microfibrous cellulose and acidic polysaccharide, which allows formulation of homogenous suspension of insoluble particles or oil droplets at a low viscosity.

Description

[0001] Composition comprising Microfibrous Cellulose and Acidic Polysaccharide and Home and Personal Care Formulation comprising the Same

[0002] Related Application

[0003] [1] This application claims priorities of European patent application EP 25169620.9 filed on April 10, 2025 and Indian provisional application 202511029872 filed on March 28, 2025.

[0004] Field of the Invention

[0005] [2] The present invention relates to a composition comprising microfibrous cellulose and acidic polysaccharide, which allows formulation of homogenous suspension of insoluble particles or oil droplets at a low viscosity.

[0006] Background of the Invention

[0007] [3] In the realm of personal care products, formulations such as skin lotions serums, tonners, washes such as body washes, face washes, shampoos etc often seek to incorporate aesthetic enhancements like beads, mica particles and oil droplets to provide a visually appealing and sensorial experience for users. These additives are intended to contribute a luxurious texture and visual shimmer, exfoliating properties or moisturisation of the product. However, their inclusion poses several challenges, primarily related to stability and sedimentation or creaming I separation. Beads and mica have a natural tendency to settle over time due to gravity, while oil droplets or a few beads with low density tend to show creaming behaviour (accumulation on top of the product) leading to an uneven distribution and a less desirable consumer experience.

[0008] [4] To address these stability issues, manufacturers commonly rely on a variety of additives, most notably acrylate-based thickeners or rheology modifiers. Acrylates function effectively in increasing the viscosity of the formulation,thereby assisting in the suspension of beads and mica particles, reducing sedimentation, and maintaining a homogenous mixture. Nevertheless, acrylate use is not without drawbacks. Concerns have been raised regarding potential skin irritancy and sensitivity issues associated with acrylate polymers, especially in individuals with sensitive skin. Furthermore, there is a growing consumer demand for more "clean" and "natural" products, leading to a desire to minimize or eliminate certain synthetic ingredients from personal care formulations.

[0009] [5] Microfibrous cellulose (MFC) has been discovered to provide suspension of particulates in surfactant-thickened systems as well as in formulations with high surfactant concentrations. However, microfibrous celluloses alone fail to provide sufficient rheological benefits for certain personal care compositions, such as those with acidic pH, or where high levels of or very large / dense particulates are desired, such as in scrubs or facial cleansers, especially in low viscosity formulations. Personal care products, including body washes, necessitate a careful balance in viscosity; it must be viscous enough to provide a rich, luxurious feel during application yet fluid enough to facilitate easy dispensing and spreading on the skin. Achieving this optimal viscosity level while also maintaining ingredient stability and compatibility is a critical aspect of formulating effective personal care items.

[0010] [6] Use of acidic polysaccharide, such as succinoglycan and xanthan gum, and microcrystalline cellulose, in the home and personal care formulations has been disclosed by EP 3327107B1 and US2016184199. The main function of microcrystalline cellulose in the formulation as described in EP 3327107B1 to serve as an abrasive particle and in US2016184199 as a viscosity enhancer.

[0011] [7] Given these challenges, there exists a need for home and personal care formulations that achieve the desired aesthetic appeal and functionalbenefits — such as suspending beads and mica evenly without resorting to acrylate-based thickeners or other thickeners.

[0012] Summary of the Invention

[0013] [8] In one aspect of the present invention, a composition comprising a microfibrous cellulose and an acidic polysaccharide is provided.

[0014] [9] In another aspect of the present invention, a novel home and personal care formulation comprising the composition is provided.

[0015]

[0010] The Applicant found that the composition comprising microfibrous cellulose and the acidic polysaccharide can synergistically stabilize home and personal care formulations which comprise suspended particles or oil droplets, even at low viscosities. This can also allow sprayability of the formulations, which is considered to be an advantage as it helps maximize coverage and improves spreadability.

[0016]

[0011] The novel home and personal care formulation that excludes acrylate thickeners, yet manage to maintain appropriate viscosity levels and ensure excellent stability of added particulates, catering to evolving market trends and consumer preferences for safer and more sustainable home and personal care alternatives.

[0017] Detailed description of the Invention

[0018]

[0012] Throughout the description, including the claims, the term "comprising one" or “comprising a" should be understood as being synonymous with the term "comprising at least one", unless otherwise specified. The terms "between" and “from ... to...” should be understood as being inclusive of the limits.

[0019]

[0013] The articles “a”, “an” and “the” are used to refer to one or to more than one (i.e. , to at least one) of the grammatical object of the article.

[0014] It should be noted that in specifying any range of concentration, weight ratio or amount, any particular upper concentration, weight ratio or amount can be associated with any particular lower concentration, weight ratio or amount, respectively.

[0020]

[0015] As used herein, the term "alkyl" means a saturated hydrocarbon radical, which may be straight, branched or cyclic, such as, methyl, ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, t-butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl, iso-decyl, undecyl, dodecyl, tridecyl, iso-tridecyl tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl, docosyl, and behenyl.

[0021]

[0016] As used herein, the term "alkenyl" means an unsaturated straight, branched, or cyclic hydrocarbon radical having at least one carbon-carbon double bond per radical, such as, for example, propenyl, butenyl.

[0022]

[0017] As used herein, the terminology "(Cn-Cm)" in reference to an organic group, wherein n and m are each integer, indicates that the group may contain from n carbon atoms to m carbon atoms per group.

[0023] Composition comprising microfibrous cellulose and acidic polysaccharide

[0024]

[0018] In one aspect of the present invention, it is provided a composition comprising a microfibrous cellulose and an acidic polysaccharide, wherein the weight ratio of the microfibrous cellulose to the acidic polysaccharide is from 2.5:1 to 1:20.

[0025]

[0019] The term "microfibrous cellulose", also referred to as "microfibrillated cellulose" or "nanofibrillated cellulose" (NFC), relates to and includes cellulose fibers made by microbial fermentation, cellulose fibers made by mechanically disrupting, altering, or separating the fibers from cereal, wood, wood pulp, or cotton, or both cellulose fibers made by microbial fermentation and mechanical disruption, alteration, or separation. MFC as well as the preparation thereof is described inter alia in the Review article "Microfibrillated cellulose -its barrier properties and applications in cellulosicmaterials: A review", Lavoine et al., Carbohydrate Polymers, 2012, pp. 735- 764. The mechanical treatment of cellulose to produce MFCs can comprise the use of homogenizers, microfluidizers, grinders, or cryocrushing devices.

[0026]

[0020] In general, cellulose is an organic compound with formula (C6HioOs)n. It is a structural polysaccharide derived from beta glucose and is the primary structural component of green plants.

[0027]

[0021] Traditionally, cellulose is harvested from plant resources (e.g., cotton, wood). The cellulose is assembled from glucose, which is produced in the living plant cell from photosynthesis. Cellulose may also be made by photosynthetic plant microbes, such as unicellular plankton or algae found in the ocean.

[0028]

[0022] Cellulose can also be assembled by bacteria. However, the bacteria is typically devoid of photosynthetic capacity and usually requires glucose or organic substrate synthesized by a photosynthetic organism to assemble cellulose. Some bacteria can use methane or sulfur substrates to produce glucose and other organic substrates for cellulose (see “Microbial Cellulose: A New resource for Wood, Paper, Textile, Food and Specialty Products”, by R. M. Brown Jr., (http: / / www.botany.utexas.edu / facstaff / facpages / mbrown / position1.htm)

[0029]

[0023] One bacteria for example, acetobacter xylinum, is a non-photosynthetic organism which can procure glucose sugar etc. and convert into cellulose. As noted in the reference cited, a cell of acetobacter has a linear row of pores from which glucan chain polymer aggregates are spun. The pores can produce a cable of polymers resulting in cellulose “ribbons” and these are spun into fibrils.

[0030]

[0024] As used herein, the term "acidic polysaccharide" with respect to this invention, means a polysaccharide comprising at least one acidic functional group, such as carboxyl, phosphate or sulfate group. These functional groupsimpart a negative charge to the polysaccharide, which can influence its solubility, interaction with other molecules, and biological functions.

[0031]

[0025] Acidic polysaccharides are often found in nature and can play various roles, including structural functions in cell walls and extracellular matrices, as well as involvement in biological processes like cell signaling and molecular recognition. Examples include pectin, found in plant cell walls, and glycosaminoglycans, which are present in animal connective tissues.

[0032]

[0026] They can be classified into two main categories based on the composition of their monomer units: acidic homopolysaccharides and acidic heteropolysaccharides:

[0033] -Acidic homopolysaccharides are a type of carbohydrate composed of a single type of sugar monomer (homopolymer) that contains acidic functional groups, such as carboxyl or sulfate groups. Examples of acidic homopolysaccharides include pectin, carrageenan, etc.,

[0034] -Acidic heteropolysaccharides are a type of carbohydrate composed of two or more different sugar monomers (heteropolymer) that contain acidic functional groups, such as carboxyl or sulfate groups. Examples of acidic homopolysaccharides include xanthan gum, alginate, alycosaminoglycan, etc.

[0035]

[0027] Polysaccharides can be a straight chain of monosaccharides known as linear polysaccharides, or it can be branched known as a branched polysaccharide.

[0036]

[0028] Preferably, acidic polysaccharide of the invention may have an acidic group attached to its sugar moiety. This acidic group is mainly carboxyl group (-COOH) in nature. Some examples of naturally occurring acidic polysaccharides like gellan gum, succinoglycan, alginate, hyaluronan etc. It is found to contain glucuronic acid, pyruvic acid, acetic acid, succinic acid, glyceretic acid, mannuronic acid etc and / or its derivatives, attached to sugarmoieties and are responsible for the acidic character of the acidic polysaccharides. These polysacharides are found with a wide range of molecular weights; it may start from as low as 2000 g / mol to 100 million g / mols.

[0037]

[0029] The non-limiting examples of acidic polysaccharides are succinoglycan, gellan gum, hyaluronic acid, alginate, chondroitin sulfate etc. One can select any one said acidic polysaccharide or a combination of acidic polysaccharides. Among them, succinoglycan is preferred. Succinoglycan is a type of bacterial anionic exopolysaccharide produced from Rhizobium, Agrobacterium, and other soil bacteria.

[0038]

[0030] In a preferred embodiment, the acidic polysaccharide is selected from the group consisting of succinoglycan, gellan gum, hyaluronic acid, alginate, chondroitin sulfate and combinations thereof.

[0039]

[0031] More preferably, the acidic acidic polysaccharide is selected from the group consisting of succinoglycan, gellan gum, hyaluronic acid, chondroitin sulfate and combinations thereof.

[0040]

[0032] In some embodiments, the composition comprises a microfibrous cellulose and succinoglycan.

[0041]

[0033] Advantageously, the weight ratio of the microfibrous cellulose to the acidic polysaccharide is from 2:1 to 1:10 and preferably 1:1 to 1:6.

[0042] Home and personal care formulation comprising the composition

[0043]

[0034] As previously mentioned, the present invention also provides a home and personal care formulation comprising the composition.

[0044]

[0035] The home and personal care formulation notably comprises:

[0045] i) the composition as illustrated above; andii) a suspended particle.

[0046]

[0036] The home and personal care formulation of the present invention has favorable rheological properties and viscosity.

[0047]

[0037] In one embodiment of the present invention, the home and personal care formulation has a viscosity ranging from 10 to 25,000 cps, preferably from 10 to 5,000 cps, more preferably from 10 to 2,000 cps, and most preferably from 10 to 1,000 cps, as determined by standard LV toque Brookfield Viscometer at 25°C, Spindle-63, at 4 RPM of LV viscometer.

[0048]

[0038] Good results can be obtained when the microfibrous cellulose presents in the formulation in an amount ranging from 0.0001 to 1 wt.%, preferably 0.001 to 0.5 wt.%, more preferably 0.01 to 0.05 wt.%, based on the total weight of the formulation, especially for suspending particles as large as 3000 microns; of course it can be used at even lower levels to suspend smaller particles (1- 1000 microns, preferably 1-800 microns).

[0049]

[0039] Good results can be obtained when the acidic polysaccharide presents in the formulation in an amount ranging from 0.01 to 1 wt.%, preferably 0.05 to 0.5 wt.%, more preferably 0.1 to 0.3 wt.%, based on the total weight of the formulation.

[0050]

[0040] The suspended particle(s) which can be employed in the present invention may have a size from 1 to 3000 micron(s), even when used in small amounts. Particles which are suspended include, but not limited to perfume encapsulates, polyethylene beads, mica, pearlizers, etc. and size can vary from 1 to 3000 micron(s). Among particles which can be suspended include optical particles (e.g., TiO2, mica), capsules (containing, for example, perfume or benefit agents such as oils or emollients), bubbles, etc.

[0051]

[0041] In some embodiments, the suspended particle(s) is selected from the group consisting of cellulose beads, scrub particles, plastic beads, grinded shells, like walnut shell, grinded kernels, like apricot kernel particles, kaolin,perlite, clay, iron oxide, titanium dioxide, aluminum oxide, pumice, silica, wax beads, vegetable oils, mineral oils, and combinations thereof.

[0052]

[0042] Typically, the suspended particle(s) presents in the formulation in an amount ranging from 0.05 to 10 wt.%, preferably 0.1 to 5 wt.%, more preferably 0.1 to 3 wt.%, based on the total weight of the formulation.

[0053]

[0043] The ingredients further included in the home and personal care formulation are not limited and generally depend on the specific use of the formulation.

[0054]

[0044] In a particular embodiment, the home and personal care formulation of the present invention is a liquid cleansing formulation.

[0055]

[0045] In one embodiment, the liquid cleansing formulation comprises one or more benefit agents, such as emollients, moisturizers, conditioners, skin conditioners, or hair conditioners such as vegetable oils, including arachis oil, castor oil, cocoa butter, coconut oil, com oil, cotton seed oil, olive oil, palm kernel oil, rapeseed oil, safflower seed oil, sesame seed oil and soybean oil, esters, including butyl myristate, cetyl palmitate, decyloleate, glyceryl laurate, glyceryl ricinoleate, glyceryl stearate, glyceryl isostearate, hexyl laurate, isobutyl palmitate, isocetyl stearate, isopropyl isostearate, isopropyl laurate, isopropyl linoleate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, propylene glycol monolaurate, propylene glycol ricinoleate, propylene glycol stearate, and propylene glycol isostearate, animal fats, including acetylated lanolin alcohols, lanolin, lard, mink oil and tallow, and fatty acids and alcohols, including behenic acid, palmitic acid, stearic acid, behenyl alcohol, cetyl alcohol, eicosanyl alcohol and isocetyl alcohol; vitamins or their derivatives, such as vitamin B complex, including thiamine, nicotinic acid, biotin, pantothenic acid, choline, riboflavin, vitamin B6, vitamin B12, pyridoxine, inositol, carnitine, vitamins A,C,D,E,K and their derivatives, such as vitamin A palmitate, and pro-vitamins, e.g., panthenol (pro vitamin B5), panthenol triacetate and mixtures thereof; antioxidants; free-radical scavengers; abrasives, natural or synthetic; dyes; hair coloring agents;bleaching agents; hair bleaching agents; UV absorbers, such as benzophenone, bornelone, PABA (Para Amino Benzoic Acid), butyl PABA, cinnamidopropyl trimethyl ammonium chloride, disodium distyrylbiphenyl disulfonate, potassium methoxycinnamate; anti-UV agents, such as butyl methoxydibenzoylmethane, octyl methoxycinnamate, oxybenzone, octocrylene, octyl salicylate, phenylbenzimidazole sulfonic acid, ethyl hydroxypropyl aminobenzoate, menthyl anthranilate, aminobenzoic acid, cinoxate, diethanolamine methoxycinnamate, glyceryl aminobenzoate, titanium dioxide, zinc oxide, oxybenzone, octyl dimethyl PABA (padimate 0), red petrolatum; antimicrobial agents; antibacterial agents, such as bacitracin, erythromycin, triclosan, neomycin, tetracycline, chlortetracycline, benzethonium chloride, phenol, parachlorometa xylenol (PCMX), triclocarban (TCC), chlorhexidine gluconate (CHG), zinc pyrithione, selenium sulfide; antifungal agents; melanin regulators; tanning accelerators; depigmenting agents, such as retinoids such as retinol, kojic acid and its derivatives such as, for example, kojic dipalmitate, hydroquinone and its derivatives such as arbutin, transexam ic acid, vitamins such as niacin, vitamin C and its derivatives, azelaic acid, placertia, licorice, extracts such as chamomile and green tea, where retinol, kojic acid, and hydroquinone are preferred; skin lightening agents such as hydroquinone, catechol and its derivatives, ascorbic acid and its derivatives; skin-coloring agents, such as dihydroxyacetone; liporegulators; weight-reduction agents; anti-acne agents; antiseborrhoeic agents; anti-ageing agents; anti-wrinkle agents; keratolytic agents; anti-inflammatory agents; anti-acne agents, such as tretinoin, isotretinoin, motretinide, adapalene, tazarotene, azelaic acid, retinol, salicylic acid, benzoyl peroxide, resorcinol, antibiotics such as tetracycline and isomers thereof, erythromycin, anti-inflammatory agents such as ibuprofen, naproxen, hetprofen, botanical extracts such as alnus, arnica, artemisia capillaris, asiasarum root, calendula, chamomile, cnidium, comfrey, fennel, galla rhois, hawthorn, houttuynia, hypericum, jujube, kiwi, licorice, magnolia, olive, peppermint, philodendron, salvia, sasa albomarginata, imidazoles suchas ketoconazole and elubiol, those anti-acne agents described in Gollnick, H. et al. 196(1) Dermatology Sebaceous Glands, Acne and Related Disorders, 119-157 (1998), which is incorporated by reference herein to the extent that it is not inconsistent with the present application; refreshing agents; cicatrizing agents; vascular-protection agents; agents for the reduction of dandruff, seborrheic dermatitis, or psoriasis, such as zinc pyrithione, shale oil and derivatives thereof such as sulfonated shale oil, selenium sulfide, sulfur, salicylic acid, coal tar, povidone-iodine, imidazoles such as ketoconazole, dichlorophenyl imidazolodioxalan, clotrimazole, itraconazole, miconazole, climbazole, tioconazole, sulconazole, butoconazole, fluconazole, miconazolenitrite and any possible stereo isomers and derivatives thereof such as anthralin, piroctone olamine (Octopirox), selenium sulfide, ciclopirox olamine, anti-psoriasis agents such as vitamin D analogs, e.g. calcipotriol, calcitriol, and tacaleitrol, vitamin A analogs such as esters of vitamin A including vitamin A palmitate, retinoids, retinols, and retinoic acid, corticosteroids such as hydrocortisone, clobetasone, butyrate, clobetasol propionate; antiperspirants or deodorants, such as aluminum chlorohydrates, aluminum zirconium chlorohydrates; immunomodulators; nourishing agents; depilating agents, such as calcium thioglycolate, magnesium thioglycolate, potassium thioglycolate, strontium thioglycolate; agents for combating hair loss; reducing agents for permanent-waving; reflectants, such as mica, alumina, calcium silicate, glycol dioleate, glycol distearate, silica, sodium magnesium fluorosilicate; essential oils and fragrances.

[0056]

[0046] In one embodiment, the liquid cleansing formulation comprises from about 0.1 to about 50 pbw, more typically from about 0.3 to about 25 pbw, and still more typically from about 0.5 to 10 pbw, of one or more benefit agents.

[0057]

[0047] The liquid cleansing formulation may optionally further comprise other ingredients, such as, for example, preservatives such as benzyl alcohol, methyl paraben, propyl paraben and imidazolidinyl urea, thickeners and viscosity modifiers such as block polymers of ethylene oxide and propyleneoxide, electrolytes, such as sodium chloride, sodium sulfate, and polyvinyl alcohol, pH adjusting agents such as citric acid, succinic acid, phosphoric acid, sodium hydroxide, and sodium carbonate, perfumes, dyes, and sequestering agents, such as disodium ethylenediamine tetra-acetate. In general, liquid cleansing formulations may optionally comprise, based on 100 pbw of the liquid cleansing formulation and independently for each such ingredient, up to about 10 pbw, preferably from 0.5 pbw to about 5.0 pbw, of such other ingredients, depending on the desired properties of the formulation.

[0058]

[0048] In general, liquid cleansing formulations may optionally comprise, based on 100 pbw of the liquid cleansing formulation and independently for each such ingredient, up to about 15 pbw, preferably from 0.5 pbw to about 10 pbw, of such other ingredients, depending on the desired properties of the formulation.

[0059]

[0049] In some embodiments, the home and personal care formulation can comprise one or more anionic surfactants.

[0060]

[0050] Anionic surfactants are known. Any anionic surfactant that is acceptable for use in the intended end use application is suitable as the anionic surfactant component of the formulation of the present invention, including, for example, linear alkylbenzene sulfonates, alpha olefin sulfonates, such as sodium (C14-C16) olefin sulfonate, paraffin sulfonates, alkyl ester sulfonates, alkyl sulfates, alkyl alkoxy sulfates, alkyl sulfonates, alkyl alkoxy carboxylates, alkyl alkoxylated sulfates, monoalkyl phosphates, dialkyl phosphates, sarcosinates, sulfosuccinates, isethionates, and taurates, as well as mixtures thereof. Commonly used sulfate free anionic surfactants that are suitable as the anionic surfactant component of the formulation of the present invention include, for example, sodium- monoalkyl phosphates, sodium dialkyl phosphates, sodium lauroyl sarcosinate, lauroyl sarcosine, cocoyl sarcosinate, sodium cocoyl isethionate, disodium laureth sulfosuccinate,sodium methyl oleoyl taurate, sodium methyl cocoyl taurate, sodium laureth carboxylate, sodium trideceth carboxylate, Ultra mild amino acid based anionic surfactants include, for example sodium cocoyl glycinate, sodium lauryl glycinate, sodium socoyl alinate and various glutamates and mixtures thereof.

[0061]

[0051] In some embodiments, the home and personal care formulation can comprise one or more amphoteric surfactant(s). Non-limiting examples of amphoteric surfactants are those selected from the group consisting of alkylamidopropyl betaine, alkyl betaine, alkyl amphoacetate, alkylamidopropyl hydroxysultaine, and alkyl hydroxysultaine.

[0062]

[0052] Examples of amphoteric surfactants include disodium lauroamphodiacetate, sodium lauroamphoacetate, cetyl dimethyl betaine, cocoamidopropyl betaine, and oleyl betaine.

[0063]

[0053] Advantageously, the home and personal care formulation has a pH value from 2 to 10 and preferably from 4 to 8.

[0064]

[0054] The home and personal care formulation of the present invention is an aqueous formulation in the form of aqueous gel, suspension or emulsion.

[0065]

[0055] In some embodiments, the home and personal care formulation of the present invention is essentially free of acrylate-based as thickener or rheology modifier.

[0066]

[0056] The home and personal care formulation of the present invention is useful in, for example, personal care applications, such as shampoos, body wash, hand soap, lotions, creams, conditioners, shaving products, facial washes, neutralizing shampoos, personal wipes, and skin treatments, cosmetics and in home care applications, such as liquid detergents, laundry detergents, hard surface cleansers, dish wash liquids, toilet bowl cleaners, floor cleanser.

[0057] In a particular embodiment, the liquid cleansing formulation above mentioned is used in a manner known in the art, for example, in the case of a cleanser or shampoo, by application of the cleanser or shampoo to the skin and / or hair and optionally rinsing the cleanser or shampoo off of the skin and / or hair with water.

[0067]

[0058] Preferably, the liquid cleaning formulation is aimed at the washing / cleaning and in particular for a body-care application, such as but not limited to a shower gel, a facial cleanser, a body-wash, a liquid hand soap, a shampoo or a cleansing conditioner.

[0068] Examples

[0069]

[0059] 1. Materials

[0070] Rheozan® BLC, & Rheozan® BLC W microfibrous cellulose aqueous dispersion with other additives, commercially available from Syensqo;

[0071] Rheozan® SH, succinoglycan, commercially available from Syensqo;

[0072] Mirataine® OMG MB, blend of glycerin and cetyl betaine, commercially available from Syensqo;

[0073] Sunflower oil, is a natural oil, serves as the oil phase for the emulsion. Tried at two different dosage levels. The maintenance of homogenous dispersion requires usage of polymers;

[0074] Troycare® PE91 is a blend of phenoxyethanol and ethylhexyl glycerin, commercially available from Arxada;

[0075] Iron Oxide (red) as commercially available with tradename Koelin-919 from Koel colours;Moisturising Beads as commercially available with tradename Spraysphere SC (product code - SC-BL-VE-1101-S) from llrnang Pharmatech;

[0076] HPMC K200M as commercially available with trade name Benecel™ K 200M from Ashland;

[0077] HPMC 40-100 as commercially available with trade name Methocel™ 40- 100 from IFF;

[0078] Naternal™ Guar Gum P SGI, commercially available from Syensqo;

[0079] Rhodacal® A 246 PF, alpha olefin sulfonate, commercially available from Syensqo;

[0080] Miranol® ultra L32, sodium lauroamphoacetate, commercially available from Syensqo;

[0081] Geropon® TC CLEAR MB, Sodium Cocoyl Methyl Taurate, commercially available from Syensqo;

[0082] Geropon® CG3S, sodium cocoyl glycinate, commercially available from Syensqo;

[0083] Mirataine® LHS, lauryl hydroxysultaine, commercially available from Syensqo;

[0084] Sodium Benzoate as commercially available with Tradename Microcare® NB from THOR;

[0085] Xanthan gum as commercially available with trade name Xanthan Gum FNCS-PC from Jungbunzlauer.

[0086]

[0060] Evaluation of the synergistic effect of the microfibrous cellulose to the acidic polysaccharide

[0061] The formulations in Table 1 were prepared as follows:

[0087]

[0062] First added EDTA and Miratiane® OMG MB into water under stirring.

[0088] Following it increased the stirring speed and added sunflower oil drop by drop to form emulsion. Added Rheozan® SH in a separate vessel with some water to make slurry under stirring. Added Rheozan® BLC W to the main vessel under vigorous stirring. Continued stirring for 20 mins and then added aqueous slurry of Rheozan® SH. Added preservatives (Troycare PE91 ) under stirring. Stirred it for 5-10 mins.

[0089]

[0063] The stability was determined as follows:

[0090]

[0064] Samples were stored at different temperatures like RT, 45°C, 25°C & 4°C for 90 days, samples were removed from different stability stations to monitor the physical properties of it at different time intervals, especially the appearance. The samples at the end of any of the evaluation time points, showing homogenous appearance visually or showing homogenous distribution of beads or particles were considered to be stable, while the samples showing sedimentation, creaming or non-homogenous distribution of the beads or particles were considered to be ‘unstable’ and marked as ‘separation’.

[0091]

[0065] Time intervals were generally after 1wk, 2 wk, 1st, 2nd, 3rd month. The stability test results were listed as below, wherein S means the example of the present invention, CS means comparative example.

[0092]

[0066] The viscosity was determined as follows: Viscosity measurements at 25°C, Spindle-63, 4 RPM were taken with a standard LV toque Brookfield Viscometer.Table 1: Stability and viscosity test results

[0093] Ingredient S1 S2 S3 S4 S5 S6 CS1 CS2 CS3 CS4

[0094] %w / w %w / w %w / w %w / w %w / w %w / w %w / w %w / w %w / w %w / w

[0095] Water QS QS QS QS QS QS QS QS QS QS

[0096] EDTA 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Mirataine®

[0097] 4 4 4 4 4 4 4 4 4 4

[0098] OMG MB

[0099] Rheozan®

[0100] 0.15 0.15 0.15 0.15 0.1 0.1 0.15 0.15 - - SH

[0101] Rheozan®

[0102] BLO W

[0103] 0.03 0.03 0.075 0.075 0.075 0.075 - - 0.075 0.075

[0104] (%w / w as

[0105]

[0106] active)

[0107] Sunflower

[0108] 5 15 5 15 5 15 5 15 5 15

[0109] oil

[0110] T roycare®

[0111] 1 1 1 1 1 1 1 1 1 1

[0112] PE91

[0113] Viscosity

[0114] 185 340 495 599 360 560 NA NA NA NA

[0115] _ (CDS) _

[0116] Stability Study (Visual Appearance) at 45 deg C

[0117] 1 wk Stable Stable Stable Stable Stable Stable Separation Separation Separation Separation

[0118] 2 wk Stable Stable Stable Stable Stable Stable Separation Separation Separation Separation

[0119]

[0120] 1 mth Stable Stable Stable Stable Stable Stable Separation Separation Separation Separation

[0121] 2 mth Stable Stable Stable Stable Stable Stable Separation Separation Separation Separation

[0122] 3 mth Stable Stable Stable Stable Stable Stable Separation Separation Separation Separation

[0123]

[0124] QS means Quantity sufficient to 100%w / w.

[0125]

[0126]

[0067] As illustrated in Table 1 , examples S1 to S6 of the present invention exhibit superior suspending ability and stability by utilizing combinations of the microfibrous cellulose and the acidic in formulations having a low viscosity. Conversely, comparable performance cannot be attained in examples CS1 to CS4 in the absence of the microfibrous cellulose or the acidic polysaccharide.

[0127]

[0068] Suspending ability in formulations comprising oil and different particles

[0128]

[0069] The formulations in Table 2 were prepared as follows:

[0129]

[0070] First added EDTA and Miratiane® OMG MB into water under stirring.

[0130] Following it increased the stirring speed and added sunflower oil drop by drop to form emulsion. Added Rheozan® SH in a separate vessel with some water to make slurry under stirring. Added Rheozan® BLC W to the main vessel under vigorous stirring. Continued stirring for 20 mins and then added agueous slurry of Rheozan® SH. Added preservatives under stirring. Stirred it for 5-10 mins.

[0131]

[0071] In case of formulations S7-S9, iron oxide was first added into sunflower oil under vigorous stirring for 10-15 mins to wet it properly. Thereafter this blend was added drop by drop to water, to form emulsion.

[0132]

[0072] In the case of S10-S12 and also for CS5 & CS6, cellulose beads were added post preservative addition under moderate stirring.Table 2: Stability and viscosity test results

[0133] Ingredient S7 S8 S9 S10 S11 S12 CS5 CS6

[0134] %w / w %w / w %w / w %w / w %w / w %w / w %w / w %w / w Water QS QS QS QS QS QS QS QS

[0135] EDTA 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Mirataine

[0136] 4 4 4 4 4 4 4 4

[0137] OMG MB

[0138] Rheozan® SH 0.15 0.15 0.1 0.15 0.15 0.1 0.15 - Rheozan®

[0139] BLO W

[0140] 0.03 0.075 0.075 0.03 0.075 0.075 - 0.075 (%w / w as

[0141]

[0142] active)

[0143] Sunflower oil 15 15 15 15 15 15 15 15

[0144] T roycare®

[0145] 1 1 1 1 1 1 1 1

[0146] PE91

[0147] Iron Oxide

[0148] 0.5 0.5 0.5 - - - - - (red)

[0149] Moisturising

[0150] - - - 0.5 0.5 0.5 0.5 0.5 Beads

[0151] Viscosity(cps) 560 1820 450 985 2785 470 NA NA Stability Study (Visual Appearance) at 45 deg C

[0152]

[0153] 1 wk Stable Stable Stable Stable Stable Stable Separation Separation 2 wk Stable Stable Stable Stable Stable Stable Separation Separation 1 mth Stable Stable Stable Stable Stable Stable Separation Separation 2 mth Stable Stable Stable Stable Stable Stable Separation Separation 3 mth Stable Stable Stable Stable Stable Stable Separation Separation

[0154]

[0155] QS means Quantity Sufficient to 100%w / w.

[0156]

[0157]

[0073] The viscosity and stability were determined in the same way as mentioned above.

[0158]

[0074] As illustrated in Table 2, examples S7 to S12 of the present invention exhibit superior suspending ability and stability by utilizing combinations of the microfibrous cellulose and the acidic polysaccharide with different weight ratios in the formulations having different particles. Conversely, comparable performance cannot be attained in examples CS5 and CS6 in the absence of the microfibrous cellulose or the acidic polysaccharide.

[0159]

[0075] Suspending ability in gel formulations

[0160]

[0076] The formulations in Tables 3 and 4 were prepared as follows:

[0161]

[0077] First added EDTA and Miratiane® OMG MB into water under stirring.

[0162] Added Rheozan® SH or xanthan gum in a separate vessel with some water to make slurry under stirring for 5-10 min. Added Rheozan® BLC W to the main vessel under vigorous stirring. Continued stirring for 20 mins and then added aqueous slurry of Rheozan® SH or xanthan gum. Added preservatives (Troycare® PE91) under stirring. Stirred it for 5-10 mins. Added moisturising beads under gentle stirring and ensured homogenous dispersion of it.Table 3 Stability and viscosity test results

[0163] Ingredient S13 S14 S15 S16 CS7 CS8

[0164] Water QS QS QS QS QS QS

[0165] EDTA 0.05 0.05 0.05 0.05 0.05 0.05 Mirataine®

[0166] 4 4 4 4 4 4

[0167] OMG MB

[0168] Rheozan® SH 0.15 0.15 0.1 0.05 0.15 - Rheozan® BLC

[0169] W

[0170] 0.03 0.075 0.075 0.075 - 0.075

[0171] (%w / w as

[0172] active)

[0173] Troy care® PE91 1 1 1 1 1 1

[0174]

[0175] Moisturising

[0176] 0.5 0.5 0.5 0.5 0.5 0.5

[0177] Beads

[0178] Viscosity (cps) 300 340 250 210 280 140

[0179] Stability study (Visual appearance) at 45 Deg C

[0180] 1 wk Stable Stable Stable Stable Separation Separation

[0181] 2 wk Stable Stable Stable Stable Separation Separation

[0182] 1 mth Stable Stable Stable Stable Separation Separation

[0183] 2 mth Stable Stable Stable Separation Separation Separation

[0184] 3 mth Stable Stable Stable Separation Separation Separation

[0185]

[0186] Table 4 Stability and viscosity test results

[0187] Ingredient S17 S18 S19 S20

[0188] Water QS QS QS QS

[0189] EDTA 0.05 0.05 0.05 0.05

[0190] Mirataine®

[0191] 4 4 4 4

[0192] OMG MB

[0193] Xanthan gum 0.15 0.15 0.1 0.05

[0194] Rheozan®

[0195] BLC W(%w / w 0.03 0.075 0.075 0.075

[0196] as active)

[0197] T roycare®

[0198] 1 1 1 1 PE91

[0199]

[0200] Moisturising 0.5 0.5 0.5 0.5

[0201] Beads

[0202] Viscosity(cps) 210 320 270 190

[0203] Stability study (Visual appearance) at 45 Deg C

[0204] 1wk Separation Separation Separation Separation

[0205] 2wk Separation Separation Separation Separation

[0206] 1 mth Separation Separation Separation Separation

[0207] 2 mth Separation Separation Separation Separation

[0208]

[0209]

[0078] The viscosity and stability were determined in the same way as mentioned above.

[0210]

[0079] As illustrated in Tables 3 and 4, it showcases the application of this technology in gel based formulations without oil phase. Table 3 shows synergy between microfibrous cellulose and succinoglycan while Table 4 showcases the synergy between microfibrous cellulose and xanthan gum. It is observed that alone microfibrous cellulose or succinoglycan are not showing stable formulations however in combinations they are effective. Further it is also observed that combination of microfibrous cellulose with succinoglycan is more effective than microfibrous cellulose and xanthan gum by comparing S13-S16 with S17-S20.

[0211]

[0080] Suspending ability in formulations comprising different polymers

[0212]

[0081] The formulations in Tables 5 to 8 were prepared as follows:

[0213]

[0082] First added EDTA and Miratiane® OMG MB into water under stirring.

[0214] Following it increased the stirring speed and added sunflower oil drop by drop to form emulsion. Added xanthan gum / HPMC K200M / HPMC 40-100 / Maternal Guar Gum P SGI in a separate vessel with some water to make slurry under stirring. Added Rheozan® BLC W to the main vessel under vigorous stirring. Added preservatives under stirring. Stirred it for 5-10 mins.Table 5 Stability and viscosity test results

[0215] Ingredient S21 S22 S23

[0216] Water QS QS QS

[0217] EDTA 0.05 0.05 0.05

[0218] Mirataine® OMG

[0219] 4 4 4

[0220] MB

[0221] Xanthan gum 0.15 0.1 0.1

[0222] Rheozan® BLC W

[0223] 0.03 0.075 0.075

[0224] (%w / w active)

[0225] Sunflower oil 15 15 15

[0226] Troycare® PE91 1 1 1

[0227] Moisturising - - 0.5

[0228]

[0229] Beads

[0230] Viscosity(cps) 210 239 410

[0231] Stability study (Visual a ppearance) at 45 Deg C

[0232] 1 wk Stable Stable Stable

[0233] 2 wk Stable Stable Stable

[0234] 3 wk Stable Separation Separation

[0235] 1 mth Separation Separation Separation

[0236] 2 mth Separation Separation Separation

[0237] 3 mth Separation Separation Separation

[0238]

[0239] Table 6 Stability and viscosity test results

[0240] Ingredient CS9 CS10 CS11 CS12 Water QS QS QS QS EDTA 0.05 0.05 0.05 0.05 Mirataine® OMG MB 4 4 4 4 HPMC 40-100 0.15 0.1 0.15 0.1 Rheozan® BLC

[0241] 0.03 0.075 0.03 0.075 W(%w / w as active)

[0242] Sunflower oil 15 15 15 15 Troycare® PE91 1 1 1 1 Moisturising Beads - - 0.5 0.5 Viscosity(cps) 45 149 165 550 Stability Study (Visual Appearance) at 45 Deg C 1 wk Separation Separation Separation Separation 2 wk Separation Separation Separation Separation 1 mth Separation Separation Separation Separation 2 mth Separation Separation Separation Separation 3 mth Separation Separation Separation Separation

[0243]

[0244] Table 7 Stability and viscosity test results

[0245] Ingredient CS13 CS14 CS15 CS16 Water QS QS QS QS EDTA 0.05 0.05 0.05 0.05 Mirataine® OMG

[0246] 4 4 4 4 MB HPMC K200M 0.15 0.1 0.15 0.1 Rheozan® BLC

[0247] W(%w / w as 0.03 0.075 0.03 0.075 active)

[0248] Sunflower oil 15 15 15 15

[0249]

[0250] Troycare® PE91 1 1 1 1 Moisturising

[0251] - - 0.5 0.5 Beads

[0252] Viscosity(cps) 58 168 115 320 Stability Study (Visual Appearance) at 45 Deg C 1 wk Separation Separation Separation Separation 2 wk Separation Separation Separation Separation 1 mth Separation Separation Separation Separation 2 mth Separation Separation Separation Separation 3 mth Separation Separation Separation Separation

[0253]

[0254] Table 8 Stability and viscosity test results

[0255] Ingredient CS17 CS18 CS19 CS20 Water QS QS QS QS EDTA 0.05 0.05 0.05 0.05 Mirataine® OMG

[0256] 4 4 4 4 MB

[0257] Naternal™ Guar

[0258] Gum P SGI 0.15 0.1 0.15 0.1

[0259] Rheozan® BLC

[0260] W(%w / w as 0.03 0.075 0.03 0.075 active)

[0261] Sunflower oil 15 15 15 15 Troycare® PE91 1 1 1 1 Moisturising

[0262] - - 0.5 0.5 Beads

[0263] Viscosity(cps) 42.5 25 77 28 Stability Study (Visual Appearance) at 45 Deg C 1 wk Separation Separation Separation Separation 2 wk Separation Separation Separation Separation 1 mth Separation Separation Separation Separation

[0264]

[0265] 2 mth Separation Separation Separation Separation 3 mth Separation Separation Separation Separation

[0266]

[0267]

[0083] The viscosity and stability were determined in the same way as mentioned above.

[0268]

[0084] As illustrated in Tables 6 to 8, examples S2, S6, S10 and S12 of the present invention exhibit superior suspending ability and stability by utilizing combinations of the microfibrous cellulose and succinoglycan with different weight ratios in the formulations having oil and optionally particles. Conversely, comparable performance cannot be attained in examples CS9 to CS20 when utilizing the combinations of the microfibrous cellulose with other polymers.

[0269]

[0085] Further it is also observed that combination of microfibrous cellulose with succinoglycan is more effective than microfibrous cellulose and xanthan gum by comparing examples S2, S6, S12 with examples S21 to S23.

[0270]

[0086] Suspending ability in Cleansing formulations

[0271]

[0087] The formulations in Tables 9 to 10 were prepared as follows:

[0272]

[0088] Weighed and prepared slurry of Rheozan® SH with water under stirring. In a separate vessel, added remaining water and surfactants Rhodacal® A 246 PF or Geropon® TC CLEAR MB, Miranol® Ultra L32, Geropon® CG3S under stirring one by one. Added sodium benzoate under stirring. Ensured its complete dissolution. Added Rheozan® BLC W into the main vessel under vigorous stirring. Stirred it for the next 20 mins. Added Rheozan® SH slurry under stirring to the main vessel. Mixed well for the next 10-15 mins. Added perfume under stirring. Adjusted pH with citric acid to 5.5-7.0. Stirred well till 5-10 mins.

[0273] Table 9Ingredient S24 Water QS to 100 Rheozan® BLC W

[0274] 0.075 (%w / w active)

[0275] Rheozan® SH 0.15 Rhodacal® A 246 PF

[0276] 3.9 (%w / w solids)

[0277] Miranol® ultra L32

[0278] 4.1 (%w / w Solids)

[0279] Geropon® CG3S

[0280] 1.8 (%w / w Solids)

[0281] Sodium Benzoate 0.5

[0282] Perfume 0.5

[0283] pH 6.56 Viscosity(cps) 369 Stability study (Visual Appearance) at 45 Deg C 1 wk Stable

[0284] 2 wk Stable

[0285] 1 mth Stable

[0286] 2 mth Stable

[0287] 3 mth Stable

[0288]

[0289] Table 10

[0290] Ingredient S25

[0291] Water QS to 100 Rheozan® BLC W

[0292] 0.075 (%w / w active)

[0293] Rheozan® SH 0.15 Geropon® TC CLEAR MB

[0294] 4.9 (%w / w solids)

[0295] Mirataine® LHS

[0296] 3.0 (%w / w solids)

[0297] Geropon® CG3S

[0298] 1.8

[0299]

[0300] (%w / w solids)Sodium Benzoate 0.5

[0301] Perfume - pH 6.49

[0302] Viscosity(cps) 239

[0303] Stability Study (Visual Appearance) at 45 Deg C

[0304] 1 wk Stable

[0305] 2 wk Stable

[0306] 1 mth Stable

[0307] 2 mth Stable

[0308] 3 mth Stable

[0309]

[0310]

[0089] The viscosity and stability were determined in the same way as mentioned above.

[0311]

[0090] As illustrated in Tables 9 to 10, the combination of the acidic polysaccharide and the microfibrous cellulose are effective even in broad types of surfactant based cleansing formulations too.

Claims

C L A I M S1. A composition comprising a microfibrous cellulose and an acidic polysaccharide, wherein the weight ratio of the microfibrous cellulose to the acidic polysaccharide is from 2.5:1 to 1 :20 and the acidic polysaccharide is selected from the group consisting of succinoglycan, gellan gum, hyaluronic acid, alginate, chondroitin sulfate and combinations thereof.

2. The composition according to claim 1, wherein the weight ratio of the microfibrous cellulose to the acidic polysaccharide is from 2:1 to 1:10 and preferably 1:1 to 1:6.

3. The composition according to any one of claims 1 to 4, wherein the acidic polysaccharide is succinoglycan.

4. A home and personal care formulation comprising the composition as defined in any one of claims 1 to 3.

5. The home and personal care formulation according to claim 4, wherein the formulation comprises:i) the composition as defined in any one of claims 1 to 3; andii) a suspended particle.

6. The home and personal care formulation according to claim 4 or 5, wherein the microfibrous cellulose presents in the formulation in an amount ranging from 0.0001 to 1 wt.%, preferably 0.001 to 0.5 wt.%, more preferably 0.01 to 0.05 wt.%, based on the total weight of the formulation.

7. The home and personal care formulation according to any one of claims 4 to 6, wherein the acidic polysaccharide presents in the formulation inan amount ranging from 0.01 to 1 wt.%, preferably 0.05 to 0.5 wt.%, more preferably 0.1 to 0.3 wt.%, based on the total weight of the formulation.

8. The home and personal care formulation according to any one of claims 4 to 7, wherein the formulation has a viscosity ranging from 10 to 25,000 cps, preferably from 10 to 5,000 cps, more preferably from 10 to 2,000 cps, and most preferably from 10 to 1,000 cps, as determined by standard LV toque Brookfield Viscometer at 25°C, Spindle-63, sat 4 RPM of LV viscometer.

9. The home and personal care formulation according to any one of claims 4 to 8, wherein the suspended particle is selected from the group consisting of cellulose beads, scrub particles, plastic beads, grinded shells, like walnut shell, grinded kernels, like apricot kernel particles, kaolin, perlite, clay, iron oxide, titanium dioxide, aluminum oxide, pumice, silica, wax beads, vegetable oils, mineral oils, and combinations thereof.

10. The home and personal care formulation according to any one of claims 4 to 9, the suspended particle(s) presents in the formulation in an amount ranging from 0.05 to 10 wt.%, preferably 0.1 to 5 wt.%, more preferably 0.1 to 3 wt.%, based on the total weight of the formulation.

11. The home and personal care formulation according to any one of claims 4 to 10, wherein the formulation is an aqueous formulation in the form of aqueous gel, suspension or emulsion.

12. The home and personal care formulation according to any one of claims 4 to 11, wherein the formulation has a pH value from 2 to 10 and preferably from 4 to 8.

13. The home and personal care formulation according to any one of claims 4 to 12, wherein the formulation is essentially free of acrylate-based asthickener or rheology modifier.

14. The home and personal care formulation according to any one of claims 4 to 13, wherein the formulation is useful in personal care applications, such as shampoos, body wash, hand soap, lotions, creams, conditioners, shaving products, facial washes, neutralizing shampoos, personal wipes, and skin treatments, cosmetics and in home care applications, such as liquid detergents, laundry detergents, hard surface cleansers, dish wash liquids, toilet bowl cleaners, floor cleanser.

15. The home and personal care formulation according to any one of claims 4 to 14, wherein the formulation is obtained by sustainable manufacturing.

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