Electrical energy supply device, and connection member connectable to electrical energy supply device
Patent Information
- Application Number
- PCT/JP2026/011735
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2025-03-25
- Filing Date
- 2026-03-24
- Publication Date
- 2026-10-01
Smart Images
Figure JP2026011735_01102026_PF_FP_ABST
Abstract
Description
Electrical energy supply device, and connecting member connectable to the electrical energy supply device
[0001] The present disclosure relates to a device for supplying electrical energy to a catheter, and a connecting member connectable to a device for supplying electrical energy to a catheter.
[0002] Endovascular treatment is one of the treatment methods for vascular lesions such as head and neck aneurysms, arteriovenous malformations, arteriovenous fistulas, pulmonary vascular malformations, renal vascular malformations, renal artery stenosis, and abdominal aortic aneurysms. In endovascular treatment, embolization is used, for example, to prevent the rupture of an aneurysm by placing an embolic device having an embolization coil at a target site such as the inside of an aneurysm to promote thrombosis. In such embolization, a catheter is used that has an in-vivo indwelling member such as a coil connected to the distal end of a conductive wire via a heat-soluble connecting member. The conductive wire is connected to a high-frequency output unit of an electrical energy supply device, and when electrical energy is supplied from the high-frequency output unit to the conductive wire, the heat-soluble connecting member is heated and melted, so that the in-vivo indwelling member can be indwelled at a predetermined position. The present applicant discloses an example of such an electrical energy supply device in Patent Document 1.
[0003] Japanese Patent No. 4503575
[0004] The position of the in-vivo indwelling member when the in-vivo indwelling member is inserted into a living body can be grasped, for example, by observation under X-ray transmission. There is also known an electrical energy supply device having a function of notifying an operator that the in-vivo indwelling member has reached a detachment position. However, some operators can empirically grasp that the in-vivo indwelling member has reached the detachment position, and for such operators, the function of notifying that the in-vivo indwelling member has reached the detachment position is not necessary, and in some cases, it may interfere with concentration during the procedure.
[0005] The problem to be solved by this disclosure is to provide an electrical energy supply device that, when performing a procedure to separate and implant an in vivo implantable member in the body using a catheter having an in vivo implantable member connected to the distal end of a conductive wire via a connecting member, allows the operator to choose whether or not to be notified when the in vivo implantable member has reached the appropriate detachment position. Another problem to be solved by this disclosure is to provide a connecting member that can give an electrical energy supply device that does not have the function of notifying when the in vivo implantable member has reached the detachment position the function of notifying when the in vivo implantable member has reached the detachment position.
[0006] The disclosure is as follows: [1] An electrical energy supply device connected directly or indirectly to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a thermofusible connecting member, and the electrical energy supply device comprises a housing, a high-frequency output unit disposed within the housing, an in-vivo impedance measuring unit disposed within the housing, and a switching unit that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member in the longitudinal axis direction of the catheter based on the measured in-vivo impedance, and a non-notification mode that does not notify. [2] The electrical energy supply device according to [1], wherein the switching unit is disposed within the housing. [3] The electrical energy supply device according to [1], wherein the switching unit is disposed within a second housing separate from the housing, and the housing and the second housing are connectable. [4] The electrical energy supply device according to any one of [1] to [3], wherein the electrical energy is high-frequency power. [5] A connecting member that can be connected to an electrical energy supply device directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a thermofusible connecting member, and the connecting member comprises a second housing and a switching unit disposed within the second housing that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member relative to the longitudinal axis of the catheter based on measured in-vivo impedance and a non-notification mode that does not notify.
[0007]
[11] An electrical energy supply device connected directly or indirectly to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, and the electrical energy supply device comprises: a housing; an electrical energy output unit disposed within the housing; an internal impedance measuring unit disposed within the housing; and a switching unit that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member in the longitudinal axis direction of the catheter based on the measured internal impedance, and a non-notification mode that does not notify.
[12] The electrical energy supply device according to
[11] , wherein the connecting member is a thermofusible material, and the electrical energy output unit is a high-frequency output unit.
[13] The electrical energy supply device according to
[11] or
[12] , wherein the switching unit is disposed within the housing.
[14] The electrical energy supply device according to
[11] or
[12] , wherein the switching unit is disposed within a second housing separate from the housing, and the housing and the second housing are connectable.
[15] The electrical energy supply device according to any one of
[11] to
[14] , wherein the electrical energy supplied from the electrical energy supply device is high-frequency power.
[16] A connecting member that can be connected to an electrical energy supply device that is directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, the electrical energy supply device having a housing and a switching unit disposed within the housing that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member in the longitudinal axis direction of the catheter based on the measured in-vivo impedance and a non-notification mode that does not notify, the connecting member having a second housing and a control unit disposed within the second housing that controls the switching between the notification mode and the non-notification mode of the switching unit.
[17] The connecting member according to
[16] , wherein the electrical energy supply device has an electrical energy output unit disposed within the housing and an in-vivo impedance measuring unit disposed within the housing.
[18] The connecting member is a thermosoluble material, as described in
[16] or
[17] .
[19] A connecting member that can be connected to an electrical energy supply device that is directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, and the connecting member comprises: a second housing and a switching unit disposed within the second housing that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member in the longitudinal axis direction of the catheter based on measured in-vivo impedance and a non-notification mode that does not notify.
[20] The connecting member is a thermosoluble material, as described in
[19] .
[21] The connecting member is a thermosoluble material, as described in
[19] or
[20] .
[0008]
[31] The electrical energy supply device according to
[11] , wherein the connecting member is a heat-soluble material.
[32] The electrical energy supply device according to
[11] , wherein the electrical energy output unit is a high-frequency output unit.
[33] The electrical energy supply device according to
[11] , wherein the electrical energy supplied from the electrical energy supply device is electrical energy that cuts the connecting member.
[34] The electrical energy supply device according to any one of
[11] to
[15] , wherein the appropriate position is the position where, when the catheter is inserted into the outer cylinder member, the distal end of the connecting member reaches distal to the distal end of the outer cylinder member.
[35] The connecting member according to
[16] , wherein the connecting member is a heat-soluble material.
[36] The connecting member according to any one of
[16] to
[18] , wherein the electrical energy supplied from the electrical energy supply device is electrical energy that cuts the connecting member.
[37] The connecting member according to any one of
[16] to
[18] , wherein the electrical energy supplied from the electrical energy supply device is high-frequency power.
[38] The appropriate position is the position where, when the catheter is inserted into the outer cylinder member, the distal end of the connecting member reaches distal to the distal end of the outer cylinder member, as described in any of
[16] to
[18] .
[39] The connecting member according to
[17] , wherein the electrical energy output unit is a high-frequency output unit.
[40] The connecting member according to
[19] , wherein the connecting member is a heat-soluble material.
[41] The connecting member according to any of
[19] to
[21] , wherein the electrical energy supplied from the electrical energy supply device is electrical energy that cuts the connecting member.
[42] The connecting member according to any of
[19] to
[21] , wherein the electrical energy supplied from the electrical energy supply device is high-frequency power.
[43] The appropriate position is the position where, when the catheter is inserted into the outer cylinder member, the distal end of the connecting member reaches distal to the distal end of the outer cylinder member, as described in any of
[19] to
[21] .
[44] The connecting member according to
[20] , wherein the electrical energy output unit is a high-frequency output unit.
[0009] According to this disclosure, an electrical energy supply device can be provided that allows the operator to choose whether or not to notify the user when an implanted bio-instrument has reached the appropriate detachment position, according to the operator's request. Furthermore, according to this disclosure, a connecting member can be provided that enables an electrical energy supply device that does not have a function to notify the user when an implanted bio-instrument has reached the detachment position to have such a function.
[0010] Figure 1 is a schematic diagram showing an electrical energy supply device. Figure 2 is a schematic diagram showing another electrical energy supply device. Figure 3 is a schematic diagram showing another electrical energy supply device. Figure 4 is a schematic diagram showing an electrical energy supply device and a connecting member. Figure 5 is a schematic diagram showing another electrical energy supply device and another connecting member.
[0011] The embodiment of the electrical energy supply device is an electrical energy supply device that is directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, and the essence of the electrical energy supply device is that it has a housing, an electrical energy output unit disposed within the housing, an in-vivo impedance measuring unit disposed within the housing, and a switching unit that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member in the longitudinal axis direction of the catheter based on the measured in-vivo impedance and a non-notification mode that does not notify.
[0012] The embodiment of the connecting member is a connecting member that can be connected to an electrical energy supply device that is directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, the electrical energy supply device has a housing and a switching unit disposed within the housing that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member relative to the longitudinal axis of the catheter based on measured in-vivo impedance and a non-notification mode that does not notify, and the gist of the connecting member is that it has a second housing and a control unit disposed within the second housing that controls the switching between the notification mode and the non-notification mode of the switching unit.
[0013] The embodiment of the connecting member is a connecting member that can be connected to an electrical energy supply device that is directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, and the connecting member comprises a second housing and a switching unit disposed within the second housing that can switch between a notification mode, which notifies the operator of the appropriate position of the in-vivo implantation member relative to the longitudinal axis of the catheter based on measured in-vivo impedance, and a non-notification mode, which does not notify.
[0014] The contents of this disclosure will be described in detail below with reference to the drawings. However, this disclosure is not limited to the illustrated examples, and modifications can be made to the extent that they conform to the spirit described above and below, and all such modifications are included within the technical scope of this disclosure. In each drawing, hatching and reference numerals may be omitted for convenience, in which case refer to the specification or other drawings. Also, the dimensions of various parts in the drawings may differ from the actual dimensions, as priority is given to helping to understand the features of this disclosure.
[0015] Figure 1 is a schematic diagram showing an electrical energy supply device, and Figure 2 is a schematic diagram showing another electrical energy supply device. Figures 1 and 2 also show catheters connected to the electrical energy supply devices. In Figures 1 and 2, the same reference numerals are used for the same parts to avoid redundant explanations.
[0016] As shown in Figures 1 and 2, the catheter 2 includes a conductive wire 21, a connecting member 22, and an in-vivo implantation member 23. The connecting member 22 is located at the distal end of the conductive wire 21. The connecting member 22 may be made of a thermosoluble material. The in-vivo implantation member 23 is connected to the conductive wire 21 via the connecting member 22. As shown in Figures 1 and 2, the catheter 2 may also have an outer casing member 24. In Figures 1 and 2, the longitudinal axis direction of the catheter 2 is represented by x.
[0017] In this specification, the proximal side refers to the side of the catheter 2 closest to the user with respect to the longitudinal axis x, and the distal side refers to the opposite side of the proximal side, i.e., the side being treated. Furthermore, the distal part of each component refers to the distal half of each component, and the proximal part of each component refers to the proximal half of each component. The distal end of each component is the end located furthest distally from each component. The proximal end of each component is the end located furthest proximal from each component. In Figures 1 and 2, the left side of the figure is the distal side, and the right side of the figure is the proximal side.
[0018] Figures 1 and 2 show that the conductive wire 21 is positioned inside the lumen of the outer cylinder member 24, and the in-vivo implantation member 23 and the connecting member 22 are positioned distal to the distal end 24b of the outer cylinder member 24.
[0019] As shown in Figures 1 and 2, the electrical energy supply device 1 includes a housing 11, an electrical energy output unit 12, an internal impedance measurement unit 13, and a switching unit 14 that can switch between a notification mode, which notifies the operator of the appropriate position of the in-vivo implantation member 23 relative to the longitudinal axis x of the catheter 2 based on the measured internal impedance, and a non-notification mode, which does not notify the operator. The electrical energy supply device 1 may also have a detachment position detection unit 16, which may be electrically connected to the internal impedance measurement unit 13 and the switching unit 14. The electrical energy supply device 1 and the catheter 2 may be directly connected by a conductor, or they may be electrically connected via a wire connection unit 17, as shown in Figures 1 and 2. Examples of the wire connection unit 17 include terminals or connectors that can ensure electrical conductivity. The appropriate position of the in-vivo implantable member 23, as detected based on the measured internal impedance, refers to the position where the in-vivo implantable member 23 is positioned in a predetermined location (for example, the lumen of an aneurysm), where the in-vivo implantable member 23 and the connecting member 22 have reached distal to the distal end 24b of the outer casing member 24. In other words, the appropriate position of the in-vivo implantable member 23, as detected based on the measured internal impedance, is the position where, when the catheter 2 is inserted into the outer casing member 24, the distal end of the connecting member 22 has reached distal to the distal end 24b of the outer casing member 24 in the longitudinal axis direction x. Whether the in vivo implantable member 23 has reached the correct position can be determined, for example, by measuring the internal impedance preoperatively with the in vivo implantable member 23 and connecting member 22 positioned in the lumen of the outer cylinder member 24, using this internal impedance as a reference impedance, and detecting when the resistance value drops below the reference impedance by a predetermined set value or more when the in vivo implantable member 23 and connecting member 22 are pushed distal to the distal end 24b of the outer cylinder member 24. Specifically, it can be determined that the in vivo implantable member 23 has reached the correct position when the resistance value drops below the reference impedance by a range of 100 to 2000 Ω. The internal impedance can be measured, for example, by the AC impedance measurement method. Specifically, an AC signal can be transmitted via a conductive wire 21, and the impedance can be calculated from the phase difference and amplitude change of the returned signal.The frequency of the AC signal may be specifically between 50 kHz and 500 kHz. To improve measurement accuracy, an algorithm may be incorporated that statistically analyzes the results of multiple measurements and calculates the average value. This can suppress measurement errors. Another method for measuring internal impedance involves attaching a counter electrode plate to the patient's skin and measuring the impedance between this counter electrode plate and a conductive wire. In this case, the change in internal impedance is measured between the counter electrode plate and the conductive wire, and, similar to the case where the impedance change within the outer cylinder member 24 is utilized, it is possible to determine whether the in-vivo implantable member 23 has reached the correct position based on the difference from the reference impedance.
[0020] As shown in Figures 1 and 2, the electrical energy supply device 1 is used by connecting it to the proximal side of the catheter 2. The electrical energy supply device 1 and the catheter 2 may be directly connected by a wire, or they may be indirectly connected by placing, for example, a control device between them.
[0021] As shown in Figure 1, even if the electrical energy supply device 1 has a function to detect the appropriate position of the in-vivo implantation member 23 relative to the longitudinal axis x of the catheter 2 based on the internal impedance measured by the internal impedance measurement unit 13, the electrical energy supply device 1 has a switching unit 14 that allows it to switch between a notification mode that notifies the operator that the in-vivo implantation member 23 has reached the appropriate position and a non-notification mode that does not notify the operator. As a result, when the operator determines that it is not necessary to be notified that the in-vivo implantation member 23 has reached the appropriate release position, the operator can switch to the non-notification mode using the switching unit 14, thereby providing an electrical energy supply device 1 that does not notify the operator that the in-vivo implantation member 23 has reached the appropriate position. The internal impedance measurement unit 13 may have, for example, an impedance calculation function and an impedance measurement circuit.
[0022] As shown in Figure 1, the switching unit 14 may be located inside the housing 11, and the electrical energy output unit 12 and the internal impedance measurement unit 13 may be located inside this housing 11. The electrical energy output unit 12 may be a high-frequency output unit, a low-frequency output unit, or a DC output unit, and among these, a high-frequency output unit is preferred. The electrical energy output from the electrical energy output unit 12 may be high-frequency power, low-frequency power, or DC power, and among these, high-frequency power is preferred. If the material constituting the connecting member 22 includes an electrolytically decomposable material, the electrical energy output from the electrical energy output unit 12 may be DC power.
[0023] As shown in Figure 2, the switching unit 14 may be located in a second housing 15 separate from the housing 11, and the second housing 15 may be connectable to the housing 11. That is, the electrical energy output unit 12 and the internal impedance measurement unit 13 may be located in the housing 11, the switching unit 14 may be located in the second housing 15, and the housing 11 and the second housing 15 may be connectable. The second housing 15 corresponds to the connecting member 3 described later, and the electrical energy supply device 1 shown in Figure 2 includes both the housing 11 and the second housing 15.
[0024] The electrical energy supply device 1 has a housing 11 and a second housing 15 separate from the housing 11. A switching unit 14 is located inside the housing 11, and a control unit 18 that controls the switching between the notification mode and the non-notification mode of the switching unit 14 located inside the housing 11 may be located inside the second housing 15. An example of the configuration of this electrical energy supply device 1 is shown in Figure 3. The same reference numerals are used for the same parts as in Figures 1 and 2 to avoid redundant explanations. As shown in Figure 3, the switching unit 14 is located inside the housing 11, and the control unit 18 is located inside the second housing 15 separate from the housing 11. This allows the operator to easily switch between the notification mode and the non-notification mode of the switching unit 14 through the second housing 15, which is located within easy reach, even when the operator is at a distance from the main body (housing 11) of the electrical energy supply device 1.
[0025] The control unit 18 may be, for example, an input interface such as a button switch, slide switch, or touch panel that can be operated by the operator with their finger. When the operator operates the control unit 18, a switching signal is transmitted from the second housing 15 to the switching unit 14 on the housing 11 side via wired or wireless connection, and the system is configured to switch between a notification mode and a non-notification mode for the operator.
[0026] Methods for connecting the housing 11 and the second housing 15 include, for example, providing terminals at the ends of conductors to connect them, providing corresponding protrusions and recesses on the housing 11 and the second housing 15 and connecting them by fitting them together, and fixing them with screws. The housing 11 and the second housing 15 may each have receptacles for inserting terminals, or the edge of the housing 11 on the side connected to the second housing 15 may have a recess into which a part of the edge of the second housing 15 can be inserted. Furthermore, the edge of the second housing 15 on the side connected to the housing 11 may have a recess into which a part of the edge of the housing 11 can be inserted, or the housing 11 may have a recess (or protrusion) and the second housing 15 may have a protrusion (or recess).
[0027] For the switching unit 14, for example, a relay switch or a semiconductor switch can be used. Examples of semiconductor switch elements include IGBTs, MOSFETs, thyristors, elements using SiC semiconductors, and elements using GaN semiconductors.
[0028] Methods for notifying the operator that the implantable member 23 has reached the correct position include notifying the operator visually, notifying them auditorily, or notifying them both visually and auditorily. A visual method of notification could be, for example, illuminating a light source such as a light bulb or light-emitting diode. A auditory method could be, for example, emitting a sound. In Figure 1, the housing 11 may have a light source (e.g., a light bulb or light-emitting diode) or a speaker to notify the operator that the implantable member 23 has reached the correct position. In Figure 2, the housing 11 or the second housing 15 may have a light source to notify the operator that the implantable member 23 has reached the correct position, or may have a speaker to notify the operator that the implantable member 23 has reached the correct position.
[0029] Furthermore, when the second housing 15 is connected to the housing 11, the second housing 15 may have a display means, which is configured to show a notification regarding whether or not the in-vivo implantation member 23 has reached the appropriate position, and the notification content may be configured to be different from that when the second housing 15 is not connected. For example, the second housing 15 may be provided with a symbol that visually indicates the content of the state shown by the display means, and the meaning of the state shown may switch depending on whether or not the second housing 15 is connected, even if it is the same light-emitting body. Specifically, when the second housing 15 is not connected, the first light-emitting body may indicate a connected state, and when the second housing 15 is connected, the same first light-emitting body may be configured to indicate an undetected state. Also, the second light-emitting body may indicate a detected state only when the second housing 15 is connected, and the third light-emitting body may be configured to indicate an error state regardless of whether or not the second housing 15 is present.
[0030] Examples of materials that make up the housing 11 and the second housing 15 include resins. Examples of resins include acrylonitrile-butadiene-styrene copolymer resin (ABS), polyethylene resin, polypropylene resin, polyethylene terephthalate resin, polycarbonate resin (PC), polyamide resin, polyacetal resin (POM), polybutylene terephthalate resin (PBT), polyphenylene sulfide resin (PPS), and polyetheretherketone resin (PEEK). The materials that make up the housing 11 and the materials that make up the second housing 15 may be the same or different.
[0031] In this specification, "electrical energy" refers to the electrical energy output from the output unit 12 of the electrical energy supply device 1 and supplied to the connecting member 22 via the conductive wire 21.
[0032] The electrical energy supplied from the electrical energy output section 12 of the electrical energy supply device 1 to the conductive wire 21 of the catheter 2 can be, for example, high-frequency power, direct current power, or low-frequency power, with high-frequency power being preferred. From the viewpoint of stability of electrical energy supply, the high-frequency power supplied to the conductive wire 21 of the catheter 2 is preferably a high-frequency current with a frequency of 100 kHz or higher. When the connecting member 22 is separated by an electrochemical reaction, it is not limited to high-frequency power, and direct current power or low-frequency power may also be used. In this case, the current flowing through the conductive wire 21 causes an electrochemical reaction in the connecting member 22, which can separate the in-vivo implantation member 23.
[0033] The catheter 2 connected to the electrical energy supply device 1 has an in-vivo implantation member 23 connected to the distal end of a conductive wire 21 via a connecting member 22. The in-vivo implantation member 23 is a member that is implanted in an aneurysm, and an example of this is a wire member. The wire member may include one or more wires. The wire member may include components other than wires, but it is preferable that it is composed only of wires.
[0034] The implantable member 23 may be biocompatible and flexible. Examples of materials constituting the implantable member 23 include metal materials such as platinum, gold, titanium, tungsten, tantalum, palladium, rhodium, or alloys thereof, and stainless steel. These may be used individually or in combination of two or more. Platinum or platinum-tungsten alloys are preferred. Since the above materials are radiopaque, the position of the implantable member 23 can be visually confirmed using an X-ray imaging device.
[0035] The shape of the in-vivo implantation member 23 may be linear, wavy, or rectangular. As shown in Figure 1, the in-vivo implantation member 23 may be a wire member, and the wire may be a coil wound in a helical shape. The coil may be a single-layer coil or a multi-layer coil having multiple layers.
[0036] The material constituting the connecting member 22 may be a thermosoluble material, an electrolytic material, or a thermosoluble and electrolytic material, with a thermosoluble material being preferred, and the connecting member 22 may contain such a material. When electrical energy is supplied to the connecting member 22, the connecting member 22 is softened, melted, or cut by heating, or decomposed or dissolved by electrolysis, thereby separating the in vivo implantable member 23 and the conductive wire 21 at the position of the connecting member 22. This allows the in vivo implantable member 23 to be implanted in the body. Examples of thermosoluble materials include resins. Examples of resins include synthetic resins such as polyolefin resins (e.g., polyethylene and polypropylene), polyamide resins (e.g., nylon), polyester resins (e.g., PET), aromatic polyetherketone resins (e.g., PEEK), polyetherpolyamide resins, polyurethane resins, polyimide resins, polyvinyl alcohol (PVA) resins, and fluororesins (e.g., polytetrafluoroethylene (PTFE), perfluoroalkoxy resins (PFA), ethylene-tetrafluoroethylene copolymers (ETFE)). These may be used individually or in combination of two or more. When using two or more in combination, materials with different melting temperatures and fusion properties may be combined, or materials with the same properties may be combined. Examples of electrolytically soluble materials include bioabsorbable metal materials such as iron, low-alloy steel, magnesium alloys, and zinc alloys.
[0037] The shape of the connecting member 22 is preferably rod-shaped or columnar, and in the case of a columnar shape, it may be cylindrical, polygonal columnar, etc.
[0038] If the connecting member 22 is made of metal, applying a voltage to the connecting member 22 will electrolyze the metal, thereby cutting the connecting member 22. Any type of metal that can be electrolyzed is acceptable, such as magnesium.
[0039] The materials constituting the conductive wire 21 include, for example, metal materials such as stainless steel, and composite materials of metal and resin. Examples of resins used in composite materials include synthetic resins such as polyolefin resins (e.g., polyethylene and polypropylene), polyamide resins (e.g., nylon), polyester resins (e.g., PET), aromatic polyetherketone resins (e.g., PEEK), polyetherpolyamide resins, polyurethane resins, polyimide resins, polyvinyl alcohol (PVA) resins, and fluororesins (e.g., PTFE, PFA, ETFE). These may be used individually or in combination of two or more.
[0040] The conductive wire 21 is preferably in the shape of a rod or a wire. The shape of the conductive wire 21 may be a straight member, a coiled member in which a wire is wound in a spiral shape, or a combination of a straight member and a coiled member.
[0041] The conductive wire 21 may have an X-ray opaque marker. Preferably, the X-ray opaque marker is placed at the distal end of the conductive wire 21. This allows the position of the conductive wire 21 to be visually identified using an X-ray imaging device.
[0042] The outer casing member 24 is used for transporting, transporting, and storing the in-vivo implantable member 23. The catheter 2 is inserted into the lumen of the outer casing member 24, which is placed inside the body cavity, and the in-vivo implantable member 23 is transported to the aneurysm to be treated.
[0043] The outer cylinder member 24 may be flexible. This allows the outer cylinder member 24 to be deformed to conform to the shape of the body cavity. Furthermore, it is preferable that the outer cylinder member 24 has elasticity in order to maintain its shape.
[0044] It is preferable that the outer cylinder member 24 has a shape such as a hollow cylindrical shape, a hollow polygonal columnar shape, or a tubular shape. Examples of the outer cylinder member 24 include: a hollow body formed by arranging one or more wire rods in a predetermined pattern; a hollow body obtained by coating a resin on at least either of the inner surface or the outer surface of the hollow body; a resin tube; or a combination of these. Examples of combinations include those connected in the longitudinal axis direction x. Examples of the hollow body in which wire rods are arranged in a predetermined pattern include a tubular body having a mesh structure formed by simply crossing or braiding wire rods, and a coil wound with wire rods. The wire rod may be one or more single wires, or may be one or more stranded wires. The resin tube can be produced, for example, by extrusion molding. When the outer cylinder member 24 is a resin tube, the outer cylinder member 24 can be composed of a single layer or a plurality of layers. The outer cylinder member 24 may have a part in the longitudinal axis direction x or the circumferential direction composed of a single layer, and the other part composed of a plurality of layers.
[0045] The outer cylinder member 24 can be composed of, for example, synthetic resins such as polyolefin resins (e.g., polyethylene, polypropylene, etc.), polyamide resins (e.g., nylon, etc.), polyester resins (e.g., PET, etc.), aromatic polyether ketone resins (e.g., PEEK, etc.), polyether polyamide resins, polyurethane resins, polyimide resins, fluororesins (e.g., PTFE, PFA, ETFE, etc.), or metals such as stainless steel, carbon steel, and nickel-titanium alloy. One of these may be used alone, or two or more of them may be used in combination.
[0046] The outer cylinder member 24 may be composed of only one member, or may be composed by connecting a plurality of members in the longitudinal axis direction x of the catheter 2. FIGS. 1 to 3 show an example in which the outer cylinder member 24 is composed of one tubular member.
[0047] A lubricious coating layer containing PTFE, PFA or the like may be formed on the outer surface of the outer cylinder member 24. This makes it easier to insert the outer cylinder member 24 into a body cavity.
[0048] The electrical energy supply device 1 may be used when treating an aneurysm, and can be particularly suitably used when treating an aneurysm in the head and neck region.
[0049] Next, the connecting member will be described with reference to FIGS. 4 and 5. FIG. 4 is a schematic diagram showing the electrical energy supply device and the connecting member, and FIG. 4 also shows a catheter connected to the connecting member. The same parts as in FIGS. 1 to 3 are denoted by the same reference numerals to avoid repeated description.
[0050] As shown in FIG. 4, the present disclosure also includes a connecting member 3 connectable to the electrical energy supply device 1 that is directly or indirectly connected to the proximal side of the catheter 2. That is, the catheter 2 has an in-vivo indwelling member 23 connected to the distal end portion of a conductive wire 21 via a connecting member 22, the electrical energy supply device 1 includes a housing 11 and a switching unit 14 disposed in the housing 11, the switching unit 14 being capable of switching between a notification mode for notifying an operator of the proper position of the in-vivo indwelling member 23 with respect to the longitudinal axis direction x of the catheter 2 based on measured in-vivo impedance and a non-notification mode in which no notification is provided, and the connecting member 3 includes a second housing 15 and a control unit 18 disposed in the second housing 15, the control unit 18 controlling switching between the notification mode and the non-notification mode of the switching unit 14. This allows the operator to easily switch between the notification mode and the non-notification mode of the switching unit 14 through the second housing 15 arranged at hand or the like even when the operator is at a position away from the main body (the housing 11) of the electrical energy supply device 1.
[0051] Examples of the control unit 18 include input interfaces such as a button switch, a slide switch, or a touch panel that can be operated by the operator with a finger or the like. When the operator operates the control unit 18, a switching signal is transmitted from the second housing 15 to the switching unit 14 on the housing 11 side via a wired or wireless connection, so that switching between the notification mode and the non-notification mode for the operator is configured.
[0052] FIG. 5 is a schematic diagram showing another electrical energy supply device and another connecting member, and FIG. 5 also shows a catheter connected to the connecting member. The same parts as in FIGS. 1 to 4 are denoted by the same reference numerals to avoid repeated description.
[0053] The disclosure also includes a connecting member 3, as shown in Figure 5, which can be connected to an electrical energy supply device 1 that is directly or indirectly connected to the proximal side of the catheter 2. Specifically, the catheter 2 has an in-vivo implantation member 23 connected to the distal end of a conductive wire 21 via a connecting member 22, and the connecting member 3 has a second housing 15 and a switching unit 14 disposed within the second housing 15 that can switch between a notification mode, which notifies the operator of the appropriate position of the in-vivo implantation member 23 with respect to the longitudinal axis x of the catheter 2 based on the measured in-vivo impedance, and a non-notification mode, which does not notify.
[0054] The electrical energy supply device 1 may include a housing 11, an electrical energy output unit 12 located within the housing 11, and an internal impedance measuring unit 13 located within the housing 11. The electrical energy output unit 12 may be a high-frequency output unit, a low-frequency output unit, or a DC output unit, with high-frequency output being preferred among these. The electrical energy output from the electrical energy output unit 12 may be high-frequency power, low-frequency power, or DC power, with high-frequency power being preferred among these.
[0055] If the electrical energy supply device 1 has an internal impedance measurement unit 13, and the internal impedance measurement unit 13 measures internal impedance and has a function to notify the operator of the appropriate position of the in-vivo implantation member 23 relative to the longitudinal axis x of the catheter 2 based on the measured internal impedance, then by connecting the above-mentioned connecting member 3 to the electrical energy supply device 1, the electrical energy supply device 1 can be given a function to switch between a notification mode that notifies the operator that the in-vivo implantation member 23 has reached the appropriate position and a non-notification mode that does not notify the operator. As a result, depending on the status of the procedure, the operator can switch between a notification mode that notifies the operator that the in-vivo implantation member 23 has reached the appropriate position and a non-notification mode that does not notify the operator. Therefore, if the operator decides that notification that the in-vivo implantation member 23 has reached the appropriate detachment position is not necessary, the operator can switch to non-notification mode using the switching unit 14. As a result, the operator does not receive unwanted notifications, which reduces the operator's stress and allows them to concentrate on the procedure.
[0056] The material constituting the connecting member 3 is resin, and as the resin, the resin exemplified as the material constituting the housing 11 and the second housing 15 can be used.
[0057] For instructions on how to connect the electrical energy supply device 1 and the connecting member 3, please refer to the explanation of how to connect the housing 11 and the second housing 15.
[0058] This application claims the benefit of priority based on Japanese Patent Application No. 2025-050447, filed on 25 March 2025. The entire contents of the specification of the aforementioned Japanese Patent Application No. 2025-050447 are incorporated herein by reference.
[0059] 1 Electrical energy supply device 2 Catheter 3 Connecting member 11 Housing 12 Electrical energy output unit 13 Internal impedance measurement unit 14 Switching unit 15 Second housing 16 Detachment position detection unit 17 Wire connection unit 21 Conductive wire 22 Connecting member 23 In-vivo implantation member 24 Outer cylinder member 24b Distal end of outer cylinder member
Claims
1. An electrical energy supply device connected directly or indirectly to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, and the electrical energy supply device comprises: a housing; an electrical energy output unit disposed within the housing; an internal impedance measuring unit disposed within the housing; and a switching unit that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member relative to the longitudinal axis of the catheter based on the measured internal impedance, and a non-notification mode that does not notify the operator.
2. The electrical energy supply device according to claim 1, wherein the connecting member is a heat-soluble member and the electrical energy output unit is a high-frequency output unit.
3. The electrical energy supply device according to claim 1 or 2, wherein the switching unit is located inside the housing.
4. The electrical energy supply device according to claim 1 or 2, wherein the switching unit is located in a second housing separate from the housing, and the housing and the second housing are connectable.
5. The electrical energy supply device according to claim 1 or 2, wherein the electrical energy supplied from the electrical energy supply device is high-frequency power.
6. A connecting member connectable to an electrical energy supply device directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, the electrical energy supply device having a housing and a switching unit disposed within the housing that can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member relative to the longitudinal axis of the catheter based on measured in-vivo impedance and a non-notification mode that does not notify, and the connecting member having a second housing and a control unit disposed within the second housing that controls the switching between the notification mode and the non-notification mode of the switching unit.
7. The connecting member according to claim 6, wherein the electrical energy supply device comprises an electrical energy output unit disposed within the housing and an internal impedance measuring unit disposed within the housing.
8. The connecting member according to claim 6 or 7, wherein the connecting member is a heat-soluble material.
9. A connecting member connectable to an electrical energy supply device directly or indirectly connected to the proximal side of a catheter, wherein the catheter has an in-vivo implantation member connected to the distal end of a conductive wire via a connecting member, and the connecting member comprises: a second housing; and a switching unit disposed within the second housing, which can switch between a notification mode that notifies the operator of the appropriate position of the in-vivo implantation member relative to the longitudinal axis of the catheter based on measured in-vivo impedance and a non-notification mode that does not notify.
10. The connecting member according to claim 9, wherein the electrical energy supply device comprises a housing, an electrical energy output unit disposed within the housing, and an internal impedance measuring unit disposed within the housing.
11. The connecting member according to claim 9 or 10, wherein the connecting member is a heat-soluble material.