Devices, systems and methods for treating the skin

Abstract

According to some embodiments, a skin treatment system comprises a console (e.g., a tower, other device or component, etc.) comprising a first station and at least a second station, wherein each station is configured to receive a container, a first conduit placing a container secured to the first station in fluid communication with a handpiece, a second conduit placing a container secured to the second station in fluid communication with the handpiece, and a selector configured to permit a user to choose whether fluid from a container secured to the first station is permitted to be transferred to the first conduit, and / or whether fluid from a container secured to the second station is permitted to be transferred to the second conduit, wherein fluid being transferred through the first conduit is fluidly isolated from fluid being transferred through the second conduit at least until such fluids reach the handpiece.

Description

EDGE.272WO PCT APPLICATIONDEVICES, SYSTEMS AND METHODS FOR TREATING THE SKINRelated Applications

[0001] This application claims priority to U.S. Provisional Patent Application No.63 / 777457 filed March 25, 2025, and U.S. Provisional Patent Application No. 63 / 899120 filed October 14, 2025. The contents of each of the priority applications listed above are incorporated herein by reference in their entireties. Any and all applications for which a foreign or domestic priority claim is identified in the Application Data Sheet as filed with the present application are hereby incorporated by reference under 37 CFR 1.57.Field

[0002] This application relates generally to skin treatment, and more specifically, to apparatuses, systems and methods for treating a person’s skin.Description of Related Art

[0003] Abrasion of the outer layer or epidermis of the skin is desirable to smooth or blend scars, blemishes, or other skin conditions that may be caused by, for example, acne, sun exposure, and aging. Standard techniques used to abrade the skin have generally been separated into two fields referred to as dermabrasion and microdermabrasion. Both techniques remove portions of the epidermis called the stratum comeum, which the body interprets as a mild injury. The body then replaces the lost skin cells, resulting in a new outer layer of skin. Additionally, despite the mild edema and erythema associated with the procedures, the skin looks and feels smoother because of the new outer layer of skin.SUMMARY

[0004] According to some embodiments, a skin treatment system comprises a console (e.g., a tower, a valving junction, other device or component, etc.) comprising a first station and at least a second station, wherein each of the first station and second station is configured to receive a container, a first conduit placing a container secured to the first station in fluid communication with a handpiece, a second conduit placing a container secured to theEDGE.272WO -1- Knobbe, Martens, Olson & Bear, LLPsecond station in fluid communication with the handpiece, and a selector configured to permit a user to choose whether fluid from a container secured to the first station is permitted to be transferred to the first conduit, and / or whether fluid from a container secured to the second station is permitted to be transferred to the second conduit, wherein fluid being transferred through the first conduit is fluidly isolated from (e.g., does not contact) fluid being transferred through the second conduit until such fluids reach the handpiece,

[0005] According to some embodiments, the console further comprises a third station, wherein the third station is configured to receive a container, the system further comprising a third conduit placing a container secured to the third station in fluid communication with the handpiece, wherein the selector is configured to permit a user to further choose whether fluid from a container secured to the third station is permitted to be transferred to the third conduit, and wherein fluid being transferred through each of the first conduit, second conduit and third conduit is fluidly isolated from (e.g., does not contact) fluid being transferred through other conduits until such fluids reach the handpiece.

[0006] According to some embodiments, a skin treatment system comprises a first station and at least a second station, wherein the first station and second station are at least partially on or within a housing, a first conduit placing a container secured to the first station in fluid communication with a handpiece, a second conduit placing a container secured to the second station in fluid communication with the handpiece, and a selector configured to permit a user to regulate a transfer of fluid from a first container secured to the first station and transfer of fluid from a second container secured to the second station a container to the handpiece via the first conduit and the second conduit, respectively, wherein fluid being transferred through the first conduit is fluidly isolated from fluid being transferred through the second conduit until such fluids reach the handpiece.

[0007] According to some embodiments, the system is further configured to fluidly couple the handpiece to a vacuum or suction source (e.g., vacuum pump). In some embodiments, the system comprises the vacuum or suction source. In some embodiments, the vacuum source is located at least partially on and / or in the console or tower. In some embodiments, when activated, the vacuum or suction source is configured to assist with the transfer of fluid from containers secured to the first station and / or the second station.EDGE.272WO -2- Knobbe, Martens, Olson & Bear, LLP

[0008] According to some embodiments, the selector comprises a manual selector. In some embodiments, the manual selector comprises a rotatable member that is configured to be moved (e.g.. by a user) between one of a plurality of distinct positions. In some embodiments, the selector comprises a knob and / or another components, device, feature and / or portion that can be manipulated and moved by the user. In some embodiments, the selector can be moved between distinct positions. In some embodiments, each of the positions designates or otherwise relates to a specific fluid source (e.g., a specific container secured to the console).

[0009] According to some embodiments, the selector comprises an electronic selector. In some embodiments, the electronic selector comprises at least one of a button, a switch, a touchscreen or any other controller.

[0010] According to some embodiments, the selector is included with the handpiece, positioned at least partially in and / or on the handpiece and / or positioned at least partially in and / or or a component that is configured to secure to the handpiece. In some embodiments, the component is configured to be secured to the handpiece, and wherein the component is configured to be in fluid communication with at least one fluid passage of the handpiece when the component is secured to the handpiece. In some embodiments, the component comprises a cartridge (e.g., dummy cartridge, other device or component, etc.) that is configured to be secured within a recess, an opening or other portion of the handpiece. In some embodiments, the component is coupled (e.g., directly or indirectly) to the first conduit and the second conduit. In some embodiments, the component is disposable.

[0011] According to some embodiments, the selector is not included with the handpiece, is not positioned at least partially in and / or on the handpiece and is not positioned at least partially in and / or or a component that is configured to secure to the handpiece. In some embodiments, the selector is positioned on the console. In some embodiments, the selector is positioned on a device or component that is separate of the system.

[0012] According to some embodiments, the selector is configured to be controlled, at least partially, via audible commands. In some embodiments, the selector is configured to be controlled via gesture control.

[0013] According to some embodiments, the first conduit and the second conduit are physically separate and distinct from one another. In some embodiments, the first conduitEDGE.272WO -3- Knobbe, Martens, Olson & Bear, LLPand the second conduit are at least partially coupled or secured to one another. In some embodiments, the first conduit and the second conduit are included in a single conduit having first and second lumens (e.g.. they are incorporated into a multi-lumen conduit).

[0014] According to some embodiments, fluid from a container secured to the first station is delivered to the handpiece sequentially relative to fluid from a container secured to the second station. In some embodiments, fluid from a container secured to the first station is delivered to the handpiece simultaneously relative to fluid from a container secured to the second station.

[0015] According to some embodiments, the console or tower comprises a removable module, the removable module comprises a fluid outlet that is configured to place a container secured to the first station of the console in fluid communication with the first conduit and a container secured to the second station of the console in fluid communication with the second conduit. In some embodiments, the removable module comprises a plurality of hydraulic components configured to place a container secured to the first station and a container secured to the second station in fluid communication with the fluid outlet, wherein contents of the containers secured to the first and second stations remain fluidly isolated from one another. In some embodiments, the plurality of hydraulic components comprises one or more of the following: a valve, a conduit or other fluid passage, a fitting, another fluid control device and / or the like. In some embodiments, the valve comprises at least one valve to regulate a flow of fluid through the removable module to the first conduit and / or the second conduit. In one embodiment, the at least one valve is configured to be controlled by, at least in part, the selector. In some embodiments, the fluid outlet comprises a coupling configured to couple the first conduit and the second conduit. In some embodiments, the coupling is configured to removably couple to a corresponding coupling that is in fluid communication with the first conduit and the second conduit. In some embodiments, the removable module outlet comprises a processor, a memory and / or any other electronic components that are configured to regulate at least one of the hydraulic components to control a flow of fluids through the removable module in accordance with a user’ s selection of the selector.

[0016] According to some embodiments, the system further comprises a display configured to identify the station of the console from which fluid from a container secured to said station is being transferred to first or second conduit. In one embodiment, the displayEDGE.272WO -4- Knobbe, Martens, Olson & Bear, LLPcomprises a display or output of the console or tower. In some embodiments, the display comprises a display device that is separate from the console. In some embodiments, the display is configured to be secured (e.g., permanently, removably or detachably, etc.) to the console or tower.

[0017] According to some embodiments, the system comprises the handpiece. In some embodiments, the handpiece is provided with the first and second conduits. In some embodiments, the handpiece is disposable. In some embodiments, the handpiece comprises a tip along a distal end of the handpiece. In one embodiment, the tip is removable relative to at least one component of the handpiece.

[0018] According to some embodiments, the handpiece is configured to abrade skin tissue when the handpiece contacts and is moved relative to said skin tissue. In some embodiments, the handpiece is configured to hydrate skin tissue.

[0019] According to some embodiments, the first station is configured to receive a container having a fluid that is different than a fluid contained in a container secured to the second station. In some embodiments, the fluids are included as part of a skin treatment protocol.

[0020] According to some embodiments, the system further comprises a user interface. In some embodiments, the user interface comprises a touchscreen device or component, a keyboard, any other controller, device and / or component.

[0021] According to some embodiments, a method of treating skin comprises using a system according to any of the embodiments disclosed herein. In some embodiments, the method comprises treating facial tissue. In some embodiments, the method comprises treating a scalp. In some embodiments, the method comprises treating skin tissue of a limb and / or a torso.

[0022] According to some embodiments, a method of treating skin comprises receiving a first container in a first station of a console of a skin treatment system, wherein the first container contains a first treatment fluid, receiving a second container in a second station of the console, wherein the second container contains a second treatment fluid, transferring a volume of the first treatment fluid from the first container to a first conduit, and transferring a volume of the second treatment fluid from the second container to a second conduit, wherein the first conduit and the second conduit are configured to be placed in fluid communicationEDGE.272WO -5- Knobbe, Martens, Olson & Bear, LLPwith a handpiece, wherein each of the first conduit and the second conduit comprises a distal end that extends to or near the handpiece, and wherein the first conduit is fluidly isolated from the second conduit such that the first treatment fluid does not contact the second treatment fluid until such fluids reach the handpiece.

[0023] According to some embodiments, a flow of fluids through the first conduit and the second conduit is controlled by at least one selector. In some embodiments, the at least one selector comprises a manual selector. In some embodiments, the at least one selector comprises a manual selector (e.g., an electronic selector). In some embodiments, the at least one selector is located at or near the handpiece. In other embodiments, the at least one selector is not located at or near the handpiece. In some embodiments, the at least one selector is located on or near the console. In some embodiments, the at least one selector is positioned on a separate device or a separate system.

[0024] According to some embodiments, the method further comprises providing a vacuum or suction force to a distal end of the handpiece by activating a vacuum or suction source, the vacuum or suction source being in fluid communication with the handpiece. In some embodiments, providing a vacuum or suction force helps draw the first treatment fluid from the first container to the first conduit and / or the second treatment fluid from the second container to the second conduit.

[0025] According to some embodiments, a pattern or sequence of transfer of the first treatment fluid to the first conduit and the second treatment fluid to the second conduit is determined manually by a user of the skin treatment system. In some embodiments, a pattern or sequence of transfer of the first treatment fluid to the first conduit and the second treatment fluid to the second conduit is determined at least partially automatically by the skin treatment system. In some embodiments, the pattern or sequence of transfer of the first and / or the second fluids depends, at least in part, on a selection by a user of a desired treatment protocol. In some embodiments, the selection of the desired treatment protocol is received using a user input device. In one embodiment, the user input device is positioned on and / or operatively coupled to the console. In one embodiment, the user input device is positioned on and / or operatively coupled to the handpiece and / or a component that is directly or indirectly coupled to the handpiece.EDGE.272WO -6- Knobbe, Martens, Olson & Bear, LLP

[0026] According to some embodiments, the handpiece is configured to abrade skin tissue when a distal end of the handpiece contacts and is moved relative to skin tissue. In some embodiments, the method comprises abrasion of skin tissue. In some embodiments, the method comprises extraction of impurities or other materials (e.g., sebum, blackheads, oil, dirt, etc.) from skin tissue.

[0027] According to some embodiments, the first treatment fluid is transferred from the first container to the first conduit sequentially relative to a transfer of the second treatment fluid from the second container to the second conduit. In some embodiments, the first treatment fluid is transferred from the first container to the first conduit simultaneously relative to a transfer of the second treatment fluid from the second container to the second conduit.

[0028] According to some embodiments, the method comprises treating facial tissue. In some embodiments, the method comprises treating a scalp. In some embodiments, the method comprises treating skin tissue of a limb and / or a torso.BRIEF DESCRIPTION OF THE DRAWINGS

[0029] These and other features, aspects and advantages of the present application are described with reference to drawings of certain embodiments, which are intended to illustrate, but not to limit, the present inventions. It is to be understood that these drawings are for the purpose of illustrating the various concepts disclosed herein and may not be to scale.

[0030] FIG. 1 illustrates a perspective view of a console or tower and a handpiece of a skin treatment system according to one embodiment;

[0031] FIG. 2 schematically illustrates a fluid flow diagram for a skin treatment system utilizing suction or vacuum to help transfer one or more fluids or other materials from a fluid source to a handpiece, according to one embodiment;

[0032] FIG. 3 schematically illustrates a fluid flow diagram for a skin treatment system configured to receive three fluid containers according to one embodiment;

[0033] FIG. 4 schematically illustrates a fluid flow diagram for a skin treatment system configured to receive three fluid containers according to one embodiment;

[0034] FIG. 5 schematically illustrates a fluid flow diagram for a skin treatment system configured to receive three fluid containers according to one embodiment;EDGE.272WO -7- Knobbe, Martens, Olson & Bear, LLP

[0035] FIGS. 6 A and 6B illustrate different views of a cartridge comprising a selector and configured to secure to a handpiece according to one embodiment;

[0036] FIG. 7 schematically illustrates a cartridge or other component configured to secure to a handpiece and comprising a selector according to one embodiment;

[0037] FIG. 8 illustrates an exploded view of a cartridge or other component configured to secure to a handpiece and comprising a selector according to one embodiment.

[0038] FIG. 9 schematically illustrates a fluid flow diagram for a skin treatment system configured to receive three fluid containers and comprising a module according to one embodiment;

[0039] FIGS. 10A and 10B illustrate a skin treatment system configured to receive fluid containers and comprising a module according to one embodiment;

[0040] FIG. 11 illustrates a display configured to be used with a skin treatment system according to one embodiment;

[0041] FIG. 12 illustrates an example embodiment of a multi-chambered fluid source which can include two or more separate chambers for storage of a treatment fluid;

[0042] FIG. 13A illustrates an example embodiment of a multi-chambered fluid source connected to a module for use with a treatment system; and

[0043] FIG. 13B illustrates an example embodiment of a multi-chambered fluid source connected to treatment system, and a module connected to a treatment system to draw fluid from the multi-chambered fluid source.DETAILED DESCRIPTION

[0044] Although the various embodiments of a handpiece assembly have specific relevance to an aesthetic skin treatment system, the features, advantages and other characteristics disclosed herein may have direct or indirect applicability in other applications, such as, for example, non-aesthetic skin treatment devices, medical devices, other mechanical devices and / or the like.

[0045] Several embodiments of the inventions disclosed herein are particularly advantageous because they include one, several, or all of the following benefits: provide for enhanced delivery of treatment fluids to the skin of a subject; provide for delivery of fluids toEDGE.272WO -8- Knobbe, Martens, Olson & Bear, LLPthe skin of a subject while reducing the likelihood of contamination (e.g., with other fluids that were / are being delivered); provide for delivery of fluids to the skin of a subject while reducing the amount of treatment fluid that is wasted or otherwise not delivered to the skin surface being treated; assist in providing a precise (e.g., an exact or substantially exact desired) amount of treatment fluid used in a treatment procedure to reduce or prevent waste and reduce or prevent expiration of opened treatment containers; reduce potential clogging due to expired treatment fluid remaining due to improper use of a handpiece; protect one or more components of the manifold assembly; reduce the need for a console or centralized fluid storage / delivery component or subsystem; prevent or reduce the likelihood of leaks in a manifold assembly.

[0046] With reference to the embodiment illustrated in FIG. 1, a skin treatment system 10 can include a tower or console 100 having various components and features. For example, in some configurations, the tower or console 100 is configured to receive one or more (e.g., 1, 2, 3, 4, more than 4, etc.) bottles or other containers 50 of treatment fluids to be used in a skin treatment procedure. The tower or console 100 can further include one or more waste canisters or other containers that are configured to receive spent fluids, exfoliated or otherwise removed skin tissue and / or other waste resulting from a skin treatment procedure, a vacuum or suction pump or other vacuum or suction source, a user interface or user input 120 (e.g., a touchscreen, keyboard, other input device, monitor or other output device or component, etc.), an outer housing or other exterior structure, tubing, one or more trays or other storage components 130, casters or other wheels, interior components (e.g., processor, memory, power source, sensors, tubing or other fluid conduits, channels and / or passages, valves, other flow control devices and / or other hydraulic components, electrical wiring and other electrical components, etc.) and / or the like. For example and without limitation, a console 100, e.g., as shown in the figures, can include a freestanding wheeled unit defined by a housing with a display or configured to communicate and work with a display or other output. However, a console 100 as used herein can be directed toward any system or component which can receive one or more bottles or other containers 50 of treatment fluids to be used in a skin treatment procedure and should not be limited or restricted by any embodiments illustrated and / or discussed herein. Various descriptions provided herein refer to the console 100 controlling operation of one or more features or steps; however it should be understood that these features or steps could be performed by a device, system, or other component which is in direct orEDGE.272WO -9- Knobbe, Martens, Olson & Bear, LLPindirect communication with the console 100, including but not limited to a projected capacitive touch (PCT) enabled device, smart device such as a smart phone or mobile device, or other smart device.

[0047] In some embodiments, the console includes a gesture control system. A gesture control system can be configured to permit a user to modify or otherwise control or regulate at least one aspect of the operation of the system. In some embodiments, the gesture control system can allow operation of the system without the need to contact the system, facilitate operation of the system and / or provide additional benefits or advantages. For example, a user can modify (e.g., increase or decrease) a vacuum or suction pressure, modify (e.g., increase or decrease) a rate of flow or delivery of treatment material to the distal end of the handpiece (e.g., by controlling vacuum force, by regulating one or more valves or other flow control device, etc.) and / or modify any other aspect of the system. According to some embodiments, the system is configured to receive at least one command from a user using a gesture control system. In some embodiments, the gesture control system comprises at least two gesture sensors. In one embodiment, the gesture control system comprises at least four gesture sensors. Additional details regarding gesture control concepts that can be incorporated into any of the embodiments disclosed herein or equivalents thereof are included in PCT Publication WO 2023 / 064718, filed October 7, 2022 as PCT Appl. PCT / US2022 / 077811 and published on April 20, 2023. The entire contents of WO 2023 / 064718 are incorporated by reference herein and made a part of the present application.

[0048] According to certain embodiments, as schematically illustrated in FIG. 2, a skin treatment system 10 can be configured to transfer fluids and / or other treatment materials from one or more bottles or other containers 50 to a handpiece 200 (or other device configured to contact skin and / or provide treatment to skin). As illustrated in FIGS. 3 to 5, in some embodiments, the bottles or other containers 50 with treatment fluids and / or other materials can be secured to or otherwise positioned relative to a tower, console and / or other device or system 100.

[0049] In some arrangements, the bottles, canisters or other containers 50 that are designed and otherwise adapted to be secured to the tower or console 100 can be replaceable, interchangeable and / or otherwise removable (e.g., for replacement, emptying, autoclaving or other types of cleaning, etc.).EDGE.272WO -10- Knobbe, Martens, Olson & Bear, LLP

[0050] As illustrated schematically in FIG. 2, one or more valves or other flow control devices or components 430 can be positioned between a fluid source (e.g., a bottle, other container, etc.) 50 and a fluid conduit or other line 410 that places the contents of the fluid source 50 in fluid communication with a handpiece 200 or similar handheld device. Accordingly, fluid (e.g., serum, treatment fluid, other material, etc.) contained in the container or other fluid source 50 can be selectively delivered to the handpiece 200. In the illustrated embodiment, fluid and / or other contents of the container 50 can be delivered to the tip, at least in part, by a suction or vacuum force generated along one or more portions of the handpiece (e.g., the tip 250, other portion at or near the distal end or portion of the handpiece 200, etc.). Thus, in some arrangements, fluid can be drawn or “pulled” from the fluid source (e.g., bottle secured to a station of a console or tower) 50 to the handpiece 200 via a fluid conduit 410 and / or any other components or features.

[0051] As depicted schematically in FIG. 2, the handpiece 200 can include or can be configured to receive a cartridge or other component 300. The cartridge 300 can include a port or other connector that can be placed in fluid communication with the fluid conduit 410. Such a cartridge 300 can be fixedly or removably secured to and / or incorporated into (e.g., directly or indirectly) the handpiece 200, as desired or required. For example, in some embodiments, the cartridge 300 includes a “dummy” cartridge that is removably secured within a recess, slot or other opening of the handpiece 200 (e.g., a recess that extends to an exterior of the housing of the handpiece).

[0052] With continued reference to FIG. 2, the handpiece 200 can be placed in fluid communication with a waste system W. The waste system W can include, without limitation, one or more of the following devices, components and / or features: a suction source (e.g., vacuum pump), a waste canister or other waste container, one or more fluid conduits, valves and / or other hydraulic components or features and / or the like. Regardless of its exact configuration, in some embodiments, the waste system W includes or is configured to be placed in fluid communication with one or more waste conduits or lines 420. Such a waste conduit or line 420 can be configured to secure to a waste coupling or port of the handpiece assembly 200. In some arrangements, the waste coupling or port is located at or near a proximal end of the handpiece 200. However, in alternative embodiments, the waste coupling or port is located along a side or other exterior surface of the housing of the handpiece 200, asEDGE.272WO -11- Knobbe, Martens, Olson & Bear, LLPdesired or required. Any skin treatment system embodiments disclosed herein or equivalents or variations thereof can include a waste system W identical or similar to the one schematically depicted in FIG. 2.

[0053] As discussed herein, components of skin treatment system 10 can be included within and / or on a console or tower 100 (see, e.g., FIGS. 1 and 3 to 5). In some embodiments, at least some (e.g.. some, most, all, etc.) components of the skin treatment system 10 can be arranged along a main body of a console or tower 100, or be at least partially integrated within the main body of the console or tower 100. The system 10 can be configured to include and / or to be used with one or more handpieces (e.g., handpieces, other handheld devices, etc.) 200, as desired or required. Further, the system 10 can include a waste system W, which may comprise a suction or vacuum source (e.g., vacuum pump). In some embodiments, the suction or vacuum source V and / or other portions of the waste system W are included with the system (e.g., at least partially within and / or on a tower or console 100); however, in other arrangements, the system 10 is configured to selectively couple to a suction or vacuum source (e.g., a suction or vacuum source that is separate of the system) and / or other portions of the waste system W.

[0054] According to some embodiments, once activated, the vacuum or suction source (e.g., a vacuum or suction pump or other fluid transfer device) V of the waste system W can generate suction (e.g., negative pressure relative to atmospheric or ambient pressure) along the distal end (e.g., the tip 250) of a handpiece 200. In some arrangements, such a suction or vacuum force generated along the tip or distal end of a handpiece helps draw or “pull” one or more treatment fluids to the tip or distal end (e.g., via a fluid conduit 410, etc.). In some embodiments, the tip or distal end 250 of the handpiece 200 includes a peripheral lip or member that is configured to contact skin tissue. Such a peripheral lip or member can extend continuously around the distal end of the tip. In other arrangements, however, the peripheral lip or member extends only partially around the distal end of the tip.

[0055] During use, when the aesthetician or other user places the tip or distal end 250 of the handpiece 200 along a subject’s skin surface to be treated, the lip or other peripheral member can form at least a partial seal with the targeted skin surface and help generate a vacuum or suction force within an interior area circumscribed by the lip or member. In turn, according to some arrangements, the vacuum or suction force along the tip or distal end 250EDGE.272WO -12- Knobbe, Martens, Olson & Bear, LLPof the handpiece (e.g., along an interior area along the tip or distal end) can help draw fluid and / or other treatment materials from the fluid source 50 (e.g., a bottle or other container secured to a station of a console, tower or other system) to the tip or distal end (e.g.. using the suction or vacuum alone without the need for positive pressure exerted on the fluids or other treatment materials being transferred to the tip or distal end).

[0056] According to certain embodiments, as schematically illustrated in FIG. 1, one or more bottles or other containers 50a, 50b, 50c can be placed in fluid communication with a manifold assembly or other multi-branch fluid assembly or system. As discussed above, in some arrangements, as depicted schematically in FIG. 3, one or more valves or other flow control devices or components 430 can be positioned between each fluid source (e.g., a bottle) and a main fluid delivery conduit or other fluid line 410 that places the manifold assembly in fluid communication with a handpiece 200. The valves or other flow control devices 430, which can include 2-way valves, can be configured to regulate the flow of treatment materials from one or more of the bottles or other containers 50a, 50b, 50c to each of the delivery conduits 410a, 410b, 410c, and thus, to the handpiece 200. The valves 430 can also prevent or substantially prevent (or otherwise regulate a flow of) fluid from one container 50a from passing through delivery conduits 410a, 410b, 410c into any other container 50b, 50c connected to the system 100. In some embodiments, each of the fluid delivery conduits 410a, 410b, 410c are fluidly isolated from each other, to prevent fluid being transferred from one conduit from being transferred to another conduit.

[0057] For any of the embodiments disclosed herein, a handpiece 200, the fluid conduit(s) or other fluid line(s) 410 (e.g., which selectively deliver(s) fluids and / or other materials from one or more fluid sources 50) and the waste conduit(s) or other waste line(s) 420 (e.g., which transfer(s) spent fluids, exfoliated skin, oils, sebum, blackheads and other materials removed from the skin surface being treated and the like to a waste container with the assistance of a vacuum or suction source of the waste system W) can be integrated into a single conduit 400. Such combined tubing or other conduit 400 can include a multi-lumen tubing or other conduit. In other embodiments, such fluid lines 410 and waste lines 420 can be separate conduits that are secured or connected (at least partially, e.g., continuously, intermittently, etc.) for a particular length. In yet other arrangements, the fluid delivery and waste conduits or lines 410, 420 are separate from each other and are not coupled or otherwiseEDGE.272WO -13- Knobbe, Martens, Olson & Bear, LLPconnected, as desired or required. In some embodiments, the fluid lines 410, waste lines 420, or conduits 400 described herein can be clear or semi-clear (e.g., transparent or translucent, at least partially transparent or translucent, etc.) to allow for easy visual inspection of the lines. In some embodiments, the fluid lines 410, waste lines 420, or conduits 400 described herein can be opaque or semi-opaque, which can prevent or substantially prevent treatment material from getting affected by UV light.

[0058] For any of the embodiments disclosed herein and / or equivalents or variations thereof, the system can be configured to provide positive pressure (e.g., created by a pump or other fluid transfer device) to one or more portions of its fluidic or hydraulic network(s) to facilitate the transfer of fluids and / or other treatment materials from a container 50 to the fluid conduit 410 and the handpiece 200, either in addition to and / or in lieu of using suction or vacuum created along the handpiece to help draw or pull fluids and / or other treatment materials to the handpiece 200. Thus, in some embodiments, a system can utilize both vacuum force (e.g., to draw or pull fluids to a handpiece) and positive pressure (e.g., to drive or push fluids to a handpiece), as desired or required. This can be applied to any embodiment described herein or equivalent thereof.

[0059] FIG. 3 schematically illustrates an embodiment of a skin treatment system 10 that is configured to receive more than one bottle, container or other fluid source 50a, 50b, 50c. The depicted system 100 comprises a total of three containers or other fluid sources 50a, 50b, 50c. However, in other arrangements, fewer or more than three containers (e.g., 1, 2, 4, 5, more than 5, etc.) can be included, as desired or required. As shown, the containers or other fluid sources 50a, 50b, 50c can secured to or otherwise positioned at least partially on and / or within (e.g., removably) a tower, console and / or similar device, system or component 100. For example, in some arrangements, such containers 50a, 50b, 50c can be removably secured to corresponding stations and / or other receiving areas of the console. In some embodiments, the containers 50a, 50b, 50c include a head portion and / or other portion or feature (e.g., standard or non-standard coupling) to secure to a station or other receiving area of the console, tower or other device, system or component of the skin treatment system 10 configured to receive containers. In some embodiments, a singular container with multiple chambers can be connected to the system 100, where each chamber of the singular container can act as the container(s) 50a, 50b, 50c and have distinct fluids and / or contents for a particular skinEDGE.272WO -14- Knobbe, Martens, Olson & Bear, LLPtreatment or sequence of skin treatments, as discussed herein. The singular container can connect to a plurality of fluid lines 410a, 410b, 410c similar to how individual containers 50a, 50b, 50c would, to allow removal of the fluid from each of the chambers of the singular container during a skin treatment procedure. The console or other device 100 can be sized, shaped and otherwise configured to be positioned on a ground surface, on a table, counter or other raised surface and / or the like.

[0060] With continued reference to FIG. 3, each container 50a, 50b, 50c can be fluidly coupled to its own downstream fluid conduit 410a. 410b, 410c and / or other hydraulic components to selectively transfer a volume of fluid and / or other treatment material contained in the corresponding container 50a, 50b, 50c to the handpiece 200. Such a configuration can provide certain advantages and benefits in view of existing technologies, for example, technologies that utilize at least one common conduit or passage to deliver fluid and / or treatment materials from two or more different bottles, containers or other fluid sources 50a, 50b, 50c. For example, in systems where one or more fluid conduits, lines and / or other hydraulic components (e.g., valves, fittings, etc.) are configured to receive fluids and / or other materials from two or more different containers or sources 50a, 50b, 50c, cross-contamination of fluids and / or materials can occur. In some case, for instance, residual fluid and / or other material that remains in a common header or line (e.g., a fluid conduit or passage that fluidly connects two or more containers or other fluid sources to a handpiece) can contaminate, mix with and / or otherwise combine with a fluid or other material that is being transferred through such a common header or line afterwards. In some cases, such mixing or cross contamination can be undesirable or unwanted (e.g.. modifying, altering or otherwise impacting a subsequently delivered fluid or material, causing chemical reactions, forming undesirable byproducts (e.g., solid formation, other materials that may cause deposits, clogging, blockages, etc. to the fluid conduits, valves, fittings, other hydraulic components, etc.), making a subsequently delivered fluid or material less effective, harmful, dangerous, etc.) and / or the like.

[0061] The use of separate and distinct fluid conduits that can place individual containers or other fluid sources in fluid communication with a handpiece can also help decrease fluid / material cost, reduce fluid / material usage or waste and / or provide one or more advantages or benefits associated with reducing the volume of treatment fluid that is transferredEDGE.272WO -15- Knobbe, Martens, Olson & Bear, LLPout of a container 50 but that does not reach the handpiece. In some arrangements, for instance, the need to purge, clear and / or otherwise rinse one or more common headers or shared conduits can be reduced or eliminated by using individual and fluidly distinct conduits, passages and / or other lines that hydraulically couple each container or fluid source 50a, 50b, 50c with the handpiece 200. Thus, the entire volume or substantially the entire volume of a fluid or other treatment material that is transferred from a container 50a, 50b, 50c to the handpiece 200 by the dedicated fluid conduit 410a, 410b, 410c (and related fluid / hydraulic network) with little or no loss (e.g., little or no volume of fluid or treatment material is wasted, diverted to other portions of the system, needed to be purged when switching between fluids or other treatment materials etc.). Accordingly, the volume of serums, other fluids or materials and / or the like that are transferred out of a container and do not reach the handpiece can be advantageously reduced or eliminated. Relatedly, the need of frequent cleaning, rinsing and / or related procedures or actions which are caused by using a singular or other common conduit or passage to draw material from two or more containers can be reduced or eliminated. In some embodiments, the periodicity or frequency of cleaning processes may be time based, such as, by way of example and without limitation, once every day, every week, every 2 weeks, or by other time periods. In some embodiments, the periodicity or frequency of the cleaning process may be use-based, such as after one treatment, after two treatments, after five treatments, after ten treatments, after more than ten treatments, or after any number of treatments. Thus, such embodiments can reduce the amount of treatment fluids and / or other materials needed to perform skin treatment procedures, can reduce material and / or operating costs, can reduce the time to prepare a skin treatment system for a procedure, can reduce the time it takes to perform skin treatment procedures, can make the use and operation of a skin treatment system more efficient and / or more simple, can facilitate use and operation of a skin treatment system, and / or can provide additional benefits and advantages such as those described herein.

[0062] The various embodiments disclosed herein can also improve the safety of a skin treatment system and the treatment procedures that it can be used to perform. For example, as discussed above, the likelihood of cross-contamination of treatment materials (e.g., in systems, which unlike some of the embodiments disclosed herein, use one or more common headers or other shared conduits or passages) is eliminated, substantially eliminatedEDGE.272WO -16- Knobbe, Martens, Olson & Bear, LLPor reduced. Therefore, the likelihood of any negative and potentially dangerous or harmful reactions or other impacts of such unwanted contamination or mixing is reduced or eliminated.

[0063] For at least some of the embodiments disclosed herein (e.g., skin treatment systems that include a module that is removable relative to a console or tower), the use of aged, reduced effectiveness, or expired treatment fluids and / or materials (e.g., past their effective shelf life, past an expiration date, etc.) can be reduced or eliminated, at least in part, due to the fluid conduits which are each connected to a fluid source. In addition, the various embodiments disclosed herein reduce the likelihood of contact between treatment fluids or other materials and system components (e.g., electronic components, other mechanical components, etc.). In some embodiments, since a fluid source contains the exact amount or substantially the exact amount of treatment material expected to be needed for a particular treatment, potential waste due to expiring opened containers of treatment fluid can also be minimized, reduced and / or at least partially prevented.

[0064] Further, in some embodiments, the connection of the containers or other fluid sources 50a, 50b, 50c to a console, tower or similar device, system or component 100 is simplified and / or otherwise improved. For example, at least some of the embodiments disclosed herein and variations thereof can reduce or eliminate the need to replace individual bottles or other containers 50a, 50b, 50c, can provide easier access to the stations or portions of the console, tower and / or other system component, can facilitate storage and / or transportation of containers or other fluid sources 50a, 50b, 50c and / or the like. In some embodiments, the connection between the console, tower, or similar device, system or component 100 and a handpiece 200 can be simplified, to facilitate each connection between each of the individual fluid conduits, passages or lines 410a, 410b, 410c with the corresponding conduits of the handpiece 200. In some embodiments, each of the fluid delivery conduits 410a, 410b. 410c are fluidly isolated from each other, to prevent fluid being transferred from one conduit from being transferred to another conduit.

[0065] As depicted schematically in FIG. 3, the individual fluid conduits or lines 410a, 410b, 410c can be fluidly coupled (e.g., directly or indirectly) to a handpiece 200. As noted above regarding the arrangement of FIG. 2, the handpiece 200 can include or can be configured to receive a cartridge or other component 300. The cartridge 300 can include a port or other connector that can be placed in fluid communication with fluid conduits 410, 410a,EDGE.272WO -17- Knobbe, Martens, Olson & Bear, LLP410b, 410c. Such a cartridge 300 can be fixedly or removably secured to and / or incorporated into (e.g., directly or indirectly) the handpiece 200, as desired or required. For example, in some embodiments, the cartridge 300 includes a “dummy” cartridge that is removably secured within a recess, slot, other opening, or other portion of the handpiece 200 (e.g., a recess that extends to an exterior of the housing of the handpiece). In some embodiments, the cartridge can receive one or more of the fluid conduits 410, 410a. 410b, 410c from the console, tower, or similar device, system or component 100.

[0066] In some embodiments, the fluid conduits 410, 410a, 410b, 410c can each have a capacity of 15 milliliters between the valve 430 and the cartridge 300 or handpiece 200. However, in other embodiments, the capacity of the fluid conduits can be greater or less than 15 milliliters (e.g.. 10 to 15, 10, 11, 12, 13, 14, 15 to 20, 16, 17, 18, 19 milliliters, more than 20 milliliters, less than 10 milliliters, volumes between the foregoing values or ranges, etc.).

[0067] In some embodiments, the inner diameter of a fluid conduit 410a can be different (e.g., greater or less) than the inner diameter of another 410b, 410c. This can be advantageous or beneficial for one more reasons, such as, for example and without limitation, allowing for a variety of treatment materials with different viscosities to be delivered to the cartridge 300 or handpiece 200 at a desired rate. According to some embodiments, if a fluid of a first viscosity is drawn through a first conduit and a fluid of a second, higher viscosity is drawn through a second conduit, then the diameter of the second conduit may need to be higher in order for the first fluid and the second fluid to flow at the same flow rate. In some embodiments, the inner diameters of the fluid conduits can vary in size such that fluids from the treatment material sources 50a, 50b, 50c flow to the cartridge 300 or handpiece 200 at a desired rate while being affected by the same vacuum or suction source V. Advantageously, this can allow for the same vacuum or suction source V to be used for any skin treatment procedure and / or can draw the desired amount of fluid from each of the treatment material sources 50a, 50b, 50c for a particular treatment procedure. The inner diameters of fluid conduits can vary according to a desired fluidic scheme. In some embodiments, a variation of 0% to 100% (e.g., 5, 10, 15, 20, 25, 30, 40, 50, 60, 70, 80, 90, 100, 0 to 20, 20 to 40, 40 to 60, 60 to 80, 80 to 100, 0 to 50, 50 to 100, 25 to 75%, percentages between the foregoing values and ranges, greater than 100%, etc.) in inner diameter can be implemented for one or more of the conduits or other lines, as desired or required.EDGE.272WO -18- Knobbe, Martens, Olson & Bear, LLP

[0068] In some embodiments, the type of conduit 410a, 410b, 410c can be paired with the type of treatment fluid drawn from the fluid source 50a, 50b, 50c, such that the desired flow rate can be achieved using the same vacuum or suction source V, This can allow for one vacuum or suction source V to be used for various different skin treatment procedures by pairing a bundle of conduits 410a, 410b, 410c with a specific set of fluid source 50a, 50b, 50c for a specific treatment procedure; if a separate treatment procedure is performed with a set of fluid sources 50a, 50b, 50c storing fluids with different viscosities, then the bundle of conduits 410a, 410b, 410c could be swapped to better facilitate correct or improved use for those viscosities instead of requiring modifying or providing a new vacuum or suction source V. In some embodiments, the flow rate of the treatment material can be controlled by varying the speed of the vacuum or suction source V. In operations where multiple treatment materials are provided simultaneously to the skin surface, the diameters of the fluid conduits can vary such that the desired ratio between the two or more treatment materials is provided to the skin surface through use of a singular vacuum or suction source V.

[0069] In some embodiments, use of a vacuum or suction source V on a conduit 410a, 410b, 410c can result in the system attempting to pull a vacuum on the fluid conduits 410a, 410b, 410c but failing to pull any fluid. This can occur, by way of example and without limitation, when the conduits connected to the handpiece are dry or substantially dry (e.g., are missing fluid or have insufficient fluid to be drawn toward the pump). Thus, in some embodiments, a priming fluid source can be connected to the system 100 configured to apply positive pressure to one or more fluid conduits 410a, 410b, 410c and add fluid, saline, or some other neutral fluid to prime the conduit. In some configurations, this can assist with drawing treatment material to the handpiece during a skin treatment procedure. In some embodiments, the priming fluid source can connect to the system 100 in a way substantially similar to how other fluid sources 50a, 50b, 50c or cartridges 300 connect. For any of the embodiments disclosed herein, a priming fluid source (e.g., and any accompanying components) can be included with the skin treatment system (e.g., incorporated into the system, as a separate component, device or portion that is configured to work with the system, etc.).

[0070] With continued reference to the schematic of FIG. 3, in some arrangements, the individual fluid conduits or lines 410a, 410b, 410c can be coupled to a cartridge 300 or other component, member or device that is configured to removably or fixedly secured to theEDGE.272WO -19- Knobbe, Martens, Olson & Bear, LLPhandpiece 200. However, in other embodiments, the individual fluid conduits or lines 410a, 410b, 410c are directly coupled to the handpiece 200 and / or one of its components or portions, as desired or required. In some embodiments, it may be advantageous to couple the individual fluid conduits or lines 410a, 410b, 410c to a cartridge 300 or other device, member or component that can be removably secure to a handpiece. For example, such a configuration can facilitate the removal and / or replacement of the fluid conduits that fluidly couple the fluid sources 50a, 50b, 50c to the handpiece, such as for maintenance, transportation, or replacement purposes. In some embodiments, the cartridge 300 can be provided with the individual fluid conduits or lines 410a, 410b, 410c to facilitate removal and / or replacement as a bundle or set.

[0071] According to some embodiments, the skin treatment system 10 is configured to permit a user to select the source or sources (e.g., container, bottle, etc.) 50a, 50b, 50c from which fluid and / or other treatment material will be transferred to the handpiece 200 at a particular time during the execution of a skin treatment procedure. In other embodiments, the skin treatment system 10 is configured to regulate which fluids and / or other treatment materials are delivered to the handpiece (e.g., the order of delivery, the volume of delivery, the flowrate of delivery, etc.). In some embodiments, such regulation or control is performed fully automatically (e.g., according to a desired or recommended protocol), semi-automatically (e.g., where a user can modify one or more aspects of a procedure) and / or the like, as desired or required. In some embodiments, the skin treatment system 10 can automatically, e.g., fully or at least partially, provide fluid from a fluid source 50b immediately after or substantially immediately after fluid is removed from another fluid source 50a. In some embodiments, the skin treatment system 10 can automatically (e.g., fully or at least partially) provide fluid from a fluid source 50b after only a portion of the fluid is removed from another fluid source 50a.

[0072] In some arrangements, the skin treatment system comprises one or more valves, flow control devices and / or other hydraulic components, members and / or features to help regulate the delivery of fluids and / or other materials from the fluid containers or sources 50a, 50b, 50c to the handpiece (e.g., a cartridge 300 that is removably secured or coupled to the handpiece). By way of example and without limitation, in the embodiment schematically depicted in FIG. 4, a selector 320 is included that permits a user to choose whether to transfer fluid and / or other treatment materials from one or more of the containers or other fluid sourcesEDGE.272WO -20- Knobbe, Martens, Olson & Bear, LLP50a, 50b, 50c to the handpiece 200. The selector 320 can be positioned fluidly between the handpiece 200 and the cartridge 300. Such a selector 320 can be part of (e.g., positioned at least partially on and / or within) the handpiece itself. In other embodiments, however, the selector 320 can be located on a separate member (e.g., a cartridge 300) that is configured to secure or otherwise couple to (e.g., removably, fixedly, etc.) the handpiece 200, as desired or required. In some embodiments, the selector 320 can be a separate component relative to both the handpiece and the cartridge.

[0073] FIGS. 6A and 6B illustrate one embodiment of a handpiece 200 that is configured to receive a dummy cartridge or similar device or member 300 having a selector 320. As shown in FIGS. 6A and 6B (and schematically depicted in FIG. 4), the individual fluid conduits 410a, 410b, 410c from the fluid sources 50a, 50b, 50c can secure (e.g., directly or indirectly) to a portion of the cartridge 300 that is sized, shaped and / or otherwise configured to couple (e.g., removably) to the handpiece. In the depicted embodiment, the cartridge 300 is configured to slide within a recess or opening 230 of the handpiece. In some embodiments, once the cartridge 300 has been sufficiently advanced within the recess or opening 230 of the handpiece 200 (e.g., in the direction of arrow I in FIG. 6A), the distal end 340 of the cartridge 300 can couple to a corresponding portion or feature of the handpiece and place the cartridge in fluid communication with one or more fluid conduits and / or passages (e.g., internal conduits and / or passages) of the handpiece 200. Other ways of securing the cartridge 300 to the handpiece can be used, depending on the specific configuration of the components of the system, as desired or required. This can permit fluid to pass from one or more of the fluid conduits 410, 410a, 410b, 410c to pass through such conduits and / or passages (e.g., depending on the position of the selector 320) for delivery to the tip or distal end 250 of the handpiece assembly during use. In some embodiments, the selector 320 is configured to only allow one fluid to pass from the system 100 to the distal end 250 of the handpiece at a time.

[0074] For any of the embodiments disclosed herein or equivalents or variations thereof, the selector 320 can include a manually operated selector. In other words, the selector 320 can be a simple mechanical device that is manipulated locally by a user. However, in some embodiments, the selector 320 can be electronic or at least partially electronic (e.g., to at least partially assist with the manipulation of any valve adjustments and / or other fluidic modifications). In some arrangements, the selector 320 can include a multi-way valve or otherEDGE.272WO -21- Knobbe, Martens, Olson & Bear, LLPflow control device, component or feature that is rotatable or otherwise movable by the user (e.g., manually by direct manipulation, at least partially manually via manipulation of any buttons or other electronic controls, etc.). The selector 320 illustrated in FIGS. 6A and 6B can be rotated by a user (e.g., by a single hand of the user) during use to select the fluid or other materials being delivered to the handpiece from the containers or other fluid sources 50a, 50b, 50c. In some embodiments, the selector 320 can be controlled by the system 100 as it performs a treatment procedure. The system 100 can review / determine which step of a treatment procedure is currently being performed, which can be based in part for example and without limitation by input from an operator, by the steps previously performed by the system 100, by information read from an identification tag such as an RFID tag on a cartridge 300, a multi-chambered fluid source 700 as described elsewhere herein, or by other methods for receiving input information. The system 100 can, based on the step of the treatment procedure, control the selector 320 to direct the specific treatment fluid to be used during a skin treatment procedure. The selected treatment fluid can then be applied to the skin surface by the handpiece 200. In some embodiments, the selector 320 can include detents, visual indicators, clicks, or other feedback that can be felt, heard, seen, or otherwise observed by a user to more easily indicate which fluid or other material has been selected to be delivered to the handpiece.

[0075] FIG. 7 schematically illustrates one embodiment of a cartridge 300 that is configured to receive fluids and / or other materials from the various containers or other fluid sources 50a, 50b, 50c of the system. As shown, the individual fluid conduits or lines 410a, 410b, 410c can be fluidly coupled to corresponding internal conduits or passages 310a, 310b, 310c of the cartridge 300. The individual fluid conduits or lines 410a, 410b, 410c can be configured to couple to the cartridge 300 via one or more couplings or features. In some embodiments, the cartridge and the individual fluid conduits or lines 410a, 410b, 410c form a unitary structure (e.g., they are provided as part of a singular package or set). However, in other arrangements, the individual fluid conduits or lines 410a, 410b, 410c are provided separate of the cartridge 300 (e.g., requiring a user to connect the individual fluid conduits or lines 410a, 410b, 410c to the cartridge 300 prior to use).

[0076] For any of the embodiments disclosed herein, the individual fluid conduits or lines 410a, 410b, 410c can include separate conduits or members that are at least partially separate members (e.g., each conduit 410a is separate and distinct from another conduit 410b,EDGE.272WO -22- Knobbe, Martens, Olson & Bear, LLP410c as it progresses from the system to the cartridge 300). However, in other embodiments, the individual fluid conduits or lines 410a, 410b, 410c can be incorporated into a single multilumen conduit or line that has dedicated lumens or passages for each individual fluid conduit or line 410a, 410b, 410c. In some embodiments, other wires, conduits, sensor lines, and / or other connections between the cartridge 300 and the console or other container storage device, component or portion 100 can run along the length of the individual fluid conduits or lines 410a, 410b, 410c. In some embodiments, other wires, conduits, sensor lines, or other connections between the cartridge 300 and the console 100 can run along the length of the single multi-lumen conduit or line that has dedicated lumens or passages for each individual fluid conduit or line 410a, 410b, 410c.

[0077] In some embodiments, no conduits of the system are shared such that treatment fluid from one container or other fluid source 50a, 50b, 50c of the system does not pass through any more than one fluid conduit or line 410a, 410b, 410c. For example, according to one embodiment, treatment material from a first container 50a can only be drawn from a first conduit 410a, and the other fluid lines 410b, 410c are not in fluid communication with the first container 50a.

[0078] In some embodiments, the system can include a single fluid conduit 410 that provides treatment material to the handpiece. The single fluid conduit 410 can be fluidically connected to each of the one or more of the fluid sources 50a, 50b, 50c in a configuration such that only one, only two, or more than two of the one or more of the fluid sources 50a, 50b, 50c are connected at a time to the single fluid conduit 410.

[0079] With continued reference to the schematic depicted in FIG. 7, fluid and / or other treatment materials within the individual fluid conduits or lines 410a, 410b, 410c can be directed to a valve or fluid control member M of the cartridge 300. In some embodiments, the valve M can include a multi-way valve that regulates which individual fluid conduit(s) or line(s) 410a, 410b, 410c will be permitted to pass through the valve M to outlet conduit or passage 330. In some embodiments, the valve M can allow for unidirectional flow of fluid (e.g., fluid is not permitted to flow through the valve M into conduits 410a, 410b, 410c). As shown, fluid passing through the valve M and outlet conduit or passage 330 can be directed to an outlet or exit 340 of the cartridge 300 for delivery to one or more passages of the handpiece 200 (e.g., in a direction generally and schematically represented by arrow 350 in FIG. 7). TheEDGE.272WO -23- Knobbe, Martens, Olson & Bear, LLPoutlet 340 can include a one-way valve that prevents, substantially prevents, or otherwise reduces the likelihood of fluid from entering the cartridge 300 from the handpiece 200. The exact hydraulic configuration of the cartridge 300 can be different than shown in FIG. 7. For instance, fluid passing through the valve M can be transferred directly to an outlet or exit 340 of the cartridge 300 (e.g., without passing through one more intermediate conduits or passages 330), as desired or required.

[0080] In some embodiments, as illustrated in FIG. 7, the valve or other flow control device or member M can be included with (e.g., be part of the same component or device) and / or be secured to the selector 320. For example, the selector 320 itself can be the valve or flow control device or member M such that manually rotating or otherwise moving the selector 320 can change the position of the fluid flow pattern through the valve. In some embodiments, the selector 320 can be configured to electrically send signals or other instructions to the valve M to actuate and / or otherwise control which conduit(s) 410a, 410b, 410c is / are in fluid communication with the outlet conduit 330 and / or handpiece 200.

[0081] In some embodiments, the valve M can include one or more sensing elements configured to detect one or more characteristics of the treatment fluids used in the system. In some embodiments, the sensors are configured to detect which fluid is passing through the valve M into the handpiece 200 (e.g., perform valve state detection). In some embodiments, the selector 320 can include sensors which can detect which fluid is currently selected, and communicate that information to the system 100. In some embodiments, the console or system 100 can use this valve state and / or other resulting information to inform the system what treatment material(s) is / are being provided to the handpiece 200. The system can use this information, for example and without any limitation, to measure the amount of treatment material provided to the handpiece 200, to determine the current stage of a treatment plan, to display the current valve state on a user input 120. and / or for any other reason. In some embodiments, the information (e.g. sensed data, telemetry, sensor information, etc.) can be transmitted to the console or system 100 for processing.

[0082] For any of the embodiments disclosed herein, the selector 320 (and the associated valve(s) and / or other flow control device(s) or member(s) the selector 320 controls or regulates) can be configured to permit fluid from only a single individual fluid conduit or line 410a, 410b, 410c to pass through the valve M to the outlet 330, 340 at any particular time.EDGE.272WO -24- Knobbe, Martens, Olson & Bear, LLPIn such configurations, the cartridge 300, the handpiece 200, and thus the overall system, is / are configured for only sequential delivery of fluids and / or treatment materials to the distal end of the handpiece.

[0083] In other embodiments, the selector 320, the valving and / or other components M of the cartridge 300 can be configured to permit fluid from two or more (e.g., 2, 3, more than 3, etc.) of the individual fluid conduits or lines 410a, 410b.410c to pass through the valve M to the outlet 330, 340 simultaneously or at the same time. In such configurations, the cartridge 300, the handpiece 200, and thus the overall system, is / are configured for both sequential and simultaneous delivery of fluids and / or treatment materials to the distal end of the handpiece 200. In some embodiments, the handpiece 200 includes a mixing chamber or other system designed to combine two or more contents from the fluid conduits 410a, 410b, 410c passing through the valve M. The mixing chamber can include any chamber, recess, vessel, tank, reservoir, apparatus, other container and / or any other device, apparatus, component and / or the like that has two or more inlets for fluids to enter and one or more outlets for a mixed (e.g., combined, diluted, activated, prepared) treatment fluid to exit. In some embodiments, the mixing chamber includes one or more features that encourage the mixing of the contents from the two or more fluid inlets. In some embodiments, the features include a configuration that strategically directs the incoming fluids (e.g., the concentrated serum or other treatment fluid or material and water or other dilutant) such that their fluid flow paths at least partially cross or collide.

[0084] In some embodiments, a micromixer or similar device, component or feature can be used in lieu of or in addition to the mixing chamber for the dilution of a concentrated serum or other treatment fluid or material. A micromixer, as used herein, can include any mixing device, apparatus, component and / or feature that utilizes one or more interference surfaces and / or features (e.g., obstructions) to at least partially obstruct a fluid flow to facilitate the mixing of at least two incoming fluids. In some embodiments, the fluid path can include a tortuosity such that the at least two incoming fluids at least partially turn (or otherwise change direction) and at least temporarily move from the distal end to the proximal end before turning again to move from the proximal end to the distal end. The interference surfaces and / or features can include a singular spiral or other curved shape that changes its axisEDGE.272WO -25- Knobbe, Martens, Olson & Bear, LLPof rotation such that the treatment fluid is twisted or “churned” as it progresses through the micromixer, which can generate a multitude of alternating spiral flow paths.

[0085] The interference surfaces can include a plurality of flexible diaphragms that are configured to default to (e.g. be biased into, plastically deform from, etc.) a closed configuration. Such diaphragms or other movable or flexible members can assume an open configured with the application of sufficient force, and allow a fluid or treatment material to pass through the opening (e.g., temporary opening). The flexible diaphragms could be designed in such a way that the conversion from the closed state to the opened state happens multiple times and / or repeatably at certain flow rates. Repeated opening and closing of flexible diaphragms can promote mixing of the fluid streams (e.g., concentrated serum and water or other dilutant) by increasing turbulent flow patterns of the two or more fluids or materials being mixed.

[0086] According to some embodiments, the interference surfaces and / or features comprise a static helix or helical mixer. Such a mixer can comprise a unitary body comprising a series of curved surfaces and / or features that alternate in their direction of curvature (e.g., as the fluids progress from the proximal end to the distal end of the handpiece 200). According to some embodiments, the mixing chamber and / or micromixer used within a handpiece 200 could include any one or more (e.g., a combination of) configurations of systems or methods of mixing as disclosed herein to accomplish the required or desired mixing effect.

[0087] Additional details regarding a mixing chamber that can be incorporated into any of the embodiments disclosed herein or equivalents thereof are included in PCT Publication WO 2025 / 029827, filed July 30, 2024 as PCT Appl. PCT / US2024 / 040218 and published on February 6, 2025. The entire contents of WO 2025 / 029827 are incorporated by reference herein and made a part of the present application.

[0088] FIG. 8 illustrates an exploded perspective view of an embodiment of a cartridge 300 having a selector 320 that is identical or similar to the one shown in FIGS. 6A and 6B. As shown, the cartridge 300 can include various components positioned within an interior of an outer housing or shell 302, including, by way of example and without limitation or restriction, internal conduits or passages 310a, 310b, 310c, one way valves, other valves, couplings, O-rings, other seals, fittings, couplings and / or the like, as desired or required.EDGE.272WO -26- Knobbe, Martens, Olson & Bear, LLP

[0089] With continued reference to FIG. 8, as discussed herein, the selector 320 can include a selector or device that can be manipulated by a user (e.g., using the user’s hand, by operating one or more controls, by gesturing to a gesture control of the system, etc.). As discussed, such a selector can be fully manual, partially manual, partially electronic, fully electronic and / or the like. In some embodiments, the illustrated selector 320 comprises a rotatable portion that can be rotated to select one or more of the fluid sources 50a, 50b. 50c for passage to an outlet 330, 340 of the cartridge 300. As shown, the selector 320 can include one or more selection indicators or markings 322 to permit the user to make the desired selection. For instance, such selection indicators or markings 322 can include the number or other identifier (e.g., “1”, “2”, “3”, “A”, “B”, “C”, etc.) corresponding to the container or other fluid source 50a. 50b, 50b to be delivered through the cartridge and to the distal end (e.g., tip) 250 of a handpiece 200. In embodiments where fluids from two or more sources 50a, 50b, 50c can be delivered simultaneously through the cartridge, the selector 320 can include appropriate markings or indications (e.g.. “A+B”, “B+C”. “A+C”, “A+B+C”, etc.), as desired or required.

[0090] In the embodiments of the cartridge 300 illustrated in FIGS. 6A, 6B and 8, the markings or indicators 322 are permanently provided on the selector (and / or another device) by permanently affixed or formed numbers, letters, other characters, symbols and / or the like. However, in other arrangements, such markings or indicators 322 are configured to be displayed in an electronic display (e.g., LED display) or other output that is configured to be modified by the system. In some embodiments, such markings or indicators 322 can be present on the cartridge 300 as well as being provided on an electronic display or other output that is configured to be modified by the system. In yet other embodiments, such markings or indicators (or the information related thereto) can be communicated to the user in other ways, including non-visual ways (e.g., audibly, haptically, etc.).

[0091] For any of the embodiments disclosed herein, the selector 320 and related components that help regulate flow of fluids from the fluid sources 50a, 50b, 50c to the handpiece 200 can be incorporated or included in the handpiece 200. Thus, in such arrangements, the need for a separate cartridge 300 is eliminated. Accordingly, the various features and / or properties of the cartridge 300 (e.g., as shown in FIGS. 6A, 6B, 7 and 8) can be included in and made part of the handpiece 200.EDGE.272WO -27- Knobbe, Martens, Olson & Bear, LLP

[0092] In the embodiments illustrated in FIGS. 6A, 6B and 8 and discussed herein, the selector 320 comprises a manual or mechanical device that is configured to be moved (e.g., rotated) by a user in order to change the fluid flow from the fluid sources 50a, 50b, 50c to the distal end (e.g., the tip) 250 of the handpiece 200. However, for any of the embodiments disclosed herein, including without limitation those of FIGS. 6A, 6B and 8, the selector 320 can include an electronic device, component or member or a combination manual (e.g., mechanical) and electronic device, component or member, such as but not limited to a gesture control system. In some embodiments, a selector 320 includes a button, dial, sliding member, lever, rollerwheel and / or any other device that, when manipulated (e.g., pressed, de-pressed, rotated, slid, otherwise moved) can control, e.g., directly or indirectly, manually and / or electronically, etc., one or more valves and / or other components of the cartridge, handpiece, console or tower, etc. to regulate a flow of fluids and / or other treatment materials through the individual fluid conduits or lines 410a, 410b, 410c and the handpiece 200. Accordingly, a manual or mechanical, an electronic and / or an electromechanical selector 320 can be incorporated into any of the embodiments disclosed herein or equivalents or variations thereof.

[0093] For any of the embodiments disclosed herein, a selector 320 can be operatively coupled to (e.g., physically, mechanically, electronically, electromechanically, etc.) one or more valves, flow control features and / or other components of the handpiece (e.g., directly, through a cartridge or otherwise indirectly, etc.), the fluid conduits 410a, 410b, 410c, the console or tower 100, etc. in order to regulate the flow of fluids from one or more containers or other fluid sources 50a, 50b, 50c to the handpiece 200. Thus, according to some arrangements, the system comprises one or more valves and / or other hydraulic components that are remotely controlled. For example, such remotely controlled valves and / or other devices, components or features can be regulated by manipulation of a selector 320 (e.g., an electronic or electromechanical selector). Such embodiments can allow a skin treatment system to provide the necessary valves, other flow control devices or features and / or other hydraulic components away from the handpiece 200 and / or any components secured to the handpiece (e.g., cartridge 300). Two such embodiments are schematically illustrated in FIGS.5 and 9 and discussed in greater detail below.

[0094] As shown schematically in FIG. 5, control of fluid flow from the containers or other fluid sources 50a, 50b, 50c to the handpiece 200 can be performed, at least in part, byEDGE.272WO -28- Knobbe, Martens, Olson & Bear, LLPvalves 430a, 430b, 430c and / or other flow control devices, member or components located near (e.g., in the proximity of, closer to than other embodiments, etc.) the fluid sources 50a, 50b, 50c. In the illustrated embodiment, for example, valves are located in, at and / or near the console, tower and / or other device, system, component or member 100 to which the fluid sources are configured to secure (e.g., stations of a console or tower). As discussed herein, such valves and / or other flow control features, members or devices 430a, 430b, 430c can be remotely controlled using, for example, a selector. The selector 320 can be included on the handpiece, a device, member or component configured to secure to the handpiece 200 (e.g., a cartridge 300), the console 100, a module 500 configured to be removably or fixedly secured to a console and / or any other location.

[0095] As discussed herein, flow of treatment fluids and / or other materials from the fluid sources 50a, 50b, 50c to the handpiece 200 can be controlled exclusively through selections of the user (e.g., via manipulation of a selector 320). However, in other embodiments, flow of fluids and / or other materials from the fluid sources 50a, 50b, 50c to the handpiece 200 is regulated or controlled, at least partially, automatically (e.g., fully automatically, semi-automatically, etc.) by the system. Thus, in some embodiments, the system comprises the necessary processors, control units, computing devices, memories, algorithms, power sources (e.g., batteries or other power storage device), electric / electronic / data connections and / or other data and / or electronic components or features necessary for such automated control. Such features can be incorporated into any of the embodiments disclosed herein or variations thereof. In some embodiments, a system can be configured to permit a user to select the flow or other transfer of fluids and / or rother materials to the handpiece 200 within or pursuant to certain limits, guidelines, requirements or other boundaries. For example, the amount (e.g., total volume or mass and / or rate of flow or transfer) of a particular fluid or material can be capped or otherwise limited by a particular procedure, a time of continuous and / or accumulated transfer of one or more fluids and / or other materials can be likewise limited or regulated by the device. In some embodiments, the manufacturer and / or user are able to set certain such limits or requirements, thereby allowing customization.

[0096] With continued reference to FIG. 5, the system 10 can be configured such that one or more of the components related to the delivery of fluids from the fluid sources 50a, 50b, 50c are included in a module 500 that can be removably secured to and / or removed fromEDGE.272WO -29- Knobbe, Martens, Olson & Bear, LLPa console, tower and / or other device or system 100. Tn the illustrated embodiment, the removable module 500 houses, comprises and / or otherwise includes the fluid sources 50a, 50b, 50c, at least a portion of the fluid conduits 410a, 410b, 410c that place the fluid sources in fluid communication with the handpiece 200, the valves or other flow control devices, member or features 430a, 430b, 430c that help regulate the flow from the fluid sources toward the handpiece, electronic and / or electric components (not shown) and / or the like.

[0097] The use of such a module 500 can simplify the skin treatment system, can assist with the operation of the system 10, can improve safety and efficacy (e.g., by at least partially foolproofing decisions related to which containers or other fluid sources 50a, 50b, 50c are secured to the system) and / or provide one or more additional benefits and / or advantages. In the embodiment illustrated schematically in FIG. 5. the fluid sources 50a, 50b, 50c are included in the removable module 500. However, in other arrangements, the fluid sources 50a, 50b, 50c are not included in the removable module 500. In such embodiments, the fluid conduits, lines, passages, valves and / or other devices, components and / or features of the removable module 500 can be configured to be placed in fluid communication with the fluid sources when the fluid sources and the removable module 500 are secured to the system (e.g., the console or tower 100).

[0098] One embodiment of a module 500 can is configured to be removably secured to a console, tower or other portion or component of the skin treatment system 10 is illustrated in FIGS. 10 A and 10B. As shown, the module 500 can be shaped, sized and otherwise configured to be secured to and removed from a corresponding recess or receiving area of the console 100. The module 500 can include the necessary fluid conduits or passages, valves, other flow control devices, electronics, memory, processors, other electric and / or electronic devices or components, wired and / or wireless connections and / or the like. Such electronics, memory, processors, other electric and / or electronic devices or components, wired and / or wireless connections can connect to the skin treatment system 10 by a port 140 in the system 100. The port 140 can be positioned such that direct electrical communication between the module 500 and the system 100 is convenient, without requiring to open the housing of the system 100 to connect the module 500, such as for example having the port 140 be positioned on the outer surface of the system 100. In some embodiments, the module 500 can include an outlet fitting or coupling 510 that is configured to couple to a corresponding fitting or couplingEDGE.272WO -30- Knobbe, Martens, Olson & Bear, LLP420 that is in fluid communication with individual fluid conduits or lines 410a, 41 Ob, 410c that are in fluid communication with the handpiece 200. In some embodiments, such fittings or couplings 510, 420 comprise quick-connect features that facilitate securing the fittings or couplings to each other. The fittings or couplings can include one or more features or members (e.g., a depressible lever or tab 424) that can be manipulated to couple and / or decouple the features or members 510, 420 to one another.

[0099] FIG. 9 schematically illustrates one embodiment of a skin treatment system 10 that includes a module 500 configured to secure to a portion of a console, tower and / or other device, system and / or component of the system. As shown and as discussed above in connection with FIGS. 10A and 10B, the module 500 can include one or more valves or other flow control features 530, electronic components (e.g., processors, power sources, wired or wireless communication components, memories, etc.) 540 and / or the like. The illustrated module can include a coupling or fitting 510 to facilitate the connection to and disconnection from a corresponding coupling or fitting 420 of downstream fluid conduits or lines 410a.410b, 410c that are in fluid communication with the handpiece (not shown) to permit fluid and / or other materials to be delivered to the handpiece (e.g., in a flow direction generally represented by arrow F in FIG. 9).

[0100] With continued reference to FIG. 9, the containers or other fluid sources 50a, 50b, 50c are not included in the removable module 500. However, as discussed herein, in other embodiments (e.g., the one depicted schematically in FIG. 5), the containers or other fluid sources 50a, 50b, 50c are included in the removable module 500, as desired or required.

[0101] In some embodiments, the removable module 500 is provided together with the fluid conduits or lines 410a, 410b, 410c (e.g., with or without a cartridge, with or without the handpiece, with or without any other component or portion, etc.).

[0102] In some embodiments, the container or source (or containers or sources) from which treatment fluids and / or other materials are being transferred to the handpiece can be provided on one or more displays or other output devices. For example, in the embodiment illustrated in FIG. 11, the specific container(s) or source(s) 50a, 50b, 50c from which fluids or other materials are being transferred to the handpiece can be displayed on an integrated display or output (e.g., touchscreen) 120 of the console or tower 100. However, a separate display or output 600 can be used to provide such information, either in lieu of or in additionEDGE.272WO -31- Knobbe, Martens, Olson & Bear, LLPto an integrated display or output, as desired or required. Such a separate display or output 600 can be configured to be fixedly or removably positioned relative to the console or tower 100 and / or any other component, member and / or portion of the system.

[0103] In several arrangements disclosed herein, the system 10 comprises a total of three fluid containers or sources 50a, 50b, 50c. However, a system can comprise any number of fluid sources (e.g.. 1, 2, 3, 4, 5, 6, 7. 8, more than 8, etc.), as desired or required by a particular application or use.

[0104] In some embodiments, the system 10 can comprise a multi-chambered fluid source 700 that has two or more separate fluid chambers. In the depicted embodiment in Figure 12, the multi-chambered fluid source 700 can include chambers 710, 720, 730, 740. In some embodiments, each of the chambers 710, 720, 730, 740 can be filled with a different treatment material. FIG. 12 depicts an example embodiment of a multi-chambered fluid source 700 with a total of four chambers 710, 720, 730, 740, however more or less chambers as desired or required can be included.

[0105] In some embodiments, the number of chambers can be configured to match a specific skin treatment. In some embodiments, the multi-chambered fluid source can provide the amount of treatment material needed for one treatment. In some embodiments, the multichambered fluid source 700 can store sufficient treatment material needed for one, two, three, four, five, or more than five treatments. In some embodiments, the multi-chambered fluid source 700 can store sufficient treatment material needed for more than 10 treatments. In some embodiments, the number of chambers in the multi-chambered fluid source 700 can be paired with a specific multi lumen conduit 410 such that the viscosity of any treatment material stored in a particular chamber. In some embodiments, the system 10 can have the module 500 configured to interact with each chamber 710, 720, 730, 740 of the multi-chambered fluid source 700 to draw treatment fluid from the specific chambers.

[0106] In some embodiments, the multi-chambered fluid source 700 can include individual fluid lines 712, 722, 732, 742 such that fluid can be individually drawn from each of the multiple chambers 710, 720, 730, 740 for skin treatment procedures. In some embodiments where a singular fluid conduit provides treatment into the handpiece 200, the system 10 can control the module 500 to draw treatment material from the chambersEDGE.272WO -32- Knobbe, Martens, Olson & Bear, LLPsequentially, to prevent or substantially prevent mixing between the multiple treatment materials.

[0107] In some embodiments, the multi-chambered fluid source 700 can connect directly to the module 500, an example of which is shown in FIG. 13A. In some embodiments, the multi-chambered fluid source 700 can indirectly connect to the module 500, such as for example and without any limitation, by conduits passing through at least a portion of the system 100 (e.g., fluid conduits 410a, 410b, 410c, etc.), an example of which is shown in FIG.13B. In some embodiments, the multi-chambered fluid source 700 can connect to other portions of the system 100, such as an outer housing or other exterior structure, tubing, one or more trays or other storage components 130. In some embodiments, the multi-chambered fluid source 700 can include two, three, four, five, or more than five distinct chambers which can each store distinct treatment fluid.

[0108] In some embodiments, each chamber 710, 720, 730, 740 of the multichambered fluid source 700 can include the precise amount of treatment material required for a particular skin treatment procedure. For example and without limitation, the chambers 710, 720, 730, 740 could include only 5 to 20 milliliters (e.g., 5 to 20 ml, 5 to 10, 10 to 15, 15 to 20 ml, volumes between the foregoing, etc.) of treatment material that is provided to the skin surface. In some embodiments, each stage of a treatment procedure could continue until the entirety of the treatment material of the currently accessed chamber is exhausted.

[0109] In some embodiments, the particular quantity of and type of treatment fluid provided in each of the chambers 710, 720, 730, 740 of the multi-chambered fluid source 700 can be specifically tailored as desired or required (e.g., per the needs of a particular skin treatment protocol, the selections of a specific user, etc.). In some embodiments, the particular quantity of and type of treatment fluid provided in each of the chambers 710, 720, 730, 740 of the multi-chambered fluid source 700 can be specifically tailored to the needs of a particular patient receiving a skin treatment. In some embodiments, the particular quantity of and / or type of treatment fluid provided in each of the chambers 710, 720. 730, 740 of the multi-chambered fluid source 700 can be paired with a specific set of delivery conduits 410a, 410b, 410c with internal diameters designed to match the viscosity of the treatment fluid in each of the chambers 710, 720, 730, 740.EDGE.272WO -33- Knobbe, Martens, Olson & Bear, LLP

[0110] According to certain embodiments, one or more of the treatment fluid delivery conduits are configured to receive and transfer (e.g., toward the handpiece) a serum, other treatment fluid, material and / or the like. Alternatively or in addition, one or more of the fluid delivery conduits can be configured to receive and transfer (e.g., toward the handpiece) water (e.g., distilled, tap water, filtered, etc.), saline, other dilutants or dissolvents, other fluids and / or the like to the handpiece. Such fluids can be adapted to, at least partially, contact, dissolve, dilute, liquefy, soften and / or otherwise mix with one or more solids, gels and / or other materials positioned within or on various surfaces or portions of the handpiece (e.g., tip of the handpiece or secured to a distal end of the handpiece) and / or other treatment fluids and / or materials present or delivered (e.g., via the manifold assembly) to or near the tip-skin surface interface. In some arrangements, such fluid schemes can provide a convenient way of delivering one or more materials at the skin-tip interface and / or any other location where such materials are desired or required.

[0111] Although several embodiments and examples are disclosed herein, the present application extends beyond the specifically disclosed embodiments to other alternative embodiments and / or uses of the inventions and modifications and equivalents thereof. It is also contemplated that various combinations or subcombinations of the specific features and aspects of the embodiments may be made and still fall within the scope of the inventions. Accordingly, it should be understood that various features and aspects of the disclosed embodiments can be combined with or substituted for one another in order to form varying modes of the disclosed inventions. Thus, it is intended that the scope of the present inventions herein disclosed should not be limited by the particular disclosed embodiments described above but should be determined only by a fair reading of the claims that follow.

[0112] While the inventions are susceptible to various modifications and alternative forms, specific examples thereof have been shown in the drawings and are herein described in detail. It should be understood, however, that the inventions are not to be limited to the particular forms or methods disclosed, but, to the contrary, the inventions are to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the various embodiments described and the appended claims. Any methods disclosed herein need not be performed in the order recited. The methods summarized above and set forth in further detail below describe certain actions taken by a practitioner; however, it should be understood thatEDGE.272WO -34- Knobbe, Martens, Olson & Bear, LLPthey can also include the instruction of those actions by another party. The methods summarized above and set forth in further detail below describe certain actions taken by a user (e.g„ a professional in some instances); however, it should be understood that they can also include the instruction of those actions by another party. Thus, actions such as “moving a handpiece” or “delivering a fluid” include “instructing moving a handpiece” and “instructing delivering a fluid.” The ranges disclosed herein also encompass any and all overlap, subranges, and combinations thereof. Language such as “up to,” “at least,” “greater than,” “less than,” “between,” and the like includes the number recited. Numbers proceeded by a term such as “about” or “approximately” include the recited numbers. For example, “about 10 mm” includes “10 mm.” Terms or phrases preceded by a term such as “substantially” include the recited term or phrase. For example, “substantially parallel” includes “parallel.” Furthermore, reference to abrasion in this application can refer to and / or include microdermabrasion.

[0113] Conditional language used herein, such as, among others, “can,” “could,” “might.” “may,” “e.g„” and the like, unless specifically stated otherwise, or otherwise understood within the context as used, is generally intended to convey that certain embodiments include, while other embodiments do not include, certain features, elements and / or states. Thus, such conditional language is not generally intended to imply that features, elements and / or states are in any way required for one or more embodiments or that one or more embodiments necessarily include these features, elements and / or states.

[0114] Conjunctive language such as the phrase “at least one of X, Y, and Z,” unless specifically stated otherwise, is otherwise understood with the context as used in general to convey that an item, term, etc. may be either X, Y, or Z. Thus, such conjunctive language is not generally intended to imply that certain embodiments require the presence of at least one of X, at least one of Y, and at least one of Z.

[0115] While the above detailed description may have shown, described, and pointed out novel features as applied to various embodiments, it may be understood that various omissions, substitutions, and / or changes in the form and details of any particular embodiment may be made without departing from the spirit of the disclosure. As may be recognized, certain embodiments may be embodied within a form that does not provide all of the features and benefits set forth herein, as some features may be used or practiced separately from others.EDGE.272WO -35- Knobbe, Martens, Olson & Bear, LLP

[0116] Additionally, features described in connection with one embodiment can be incorporated into another of the disclosed embodiments, even if not expressly discussed herein, and embodiments having the combination of features still fall within the scope of the disclosure. For example, features described above in connection with one embodiment can be used with a different embodiment described herein and the combination(s) still fall(s) within the scope of the disclosure.

[0117] It should be understood that various features and aspects of the disclosed embodiments can be combined with, or substituted for, one another in order to form varying modes of the embodiments of the disclosure. Thus, it is intended that the scope of the disclosure herein should not be limited by the particular embodiments described above. Accordingly, unless otherwise stated, or unless clearly incompatible, each embodiment of this disclosure may comprise, additional to its essential features described herein, one or more features as described herein from each other embodiment disclosed herein.

[0118] Features, materials, characteristics, or groups described in conjunction with a particular aspect, embodiment, or example are to be understood to be applicable to any other aspect, embodiment or example described in this section or elsewhere in this specification unless incompatible therewith. All of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and / or all of the steps of any method or process so disclosed, may be combined in any combination, except combinations where at least some of such features and / or steps are mutually exclusive. The protection is not restricted to the details of any foregoing embodiments. The protection extends to any novel one, or any novel combination, of the features disclosed in this specification (including any accompanying claims, abstract and drawings), or to any novel one, or any novel combination, of the steps of any method or process so disclosed.

[0119] Furthermore, certain features that are described in this disclosure in the context of separate implementations can also be implemented in combination in a single implementation. Conversely, various features that are described in the context of a single implementation can also be implemented in multiple implementations separately or in any suitable subcombination. Moreover, although features may be described above as acting in certain combinations, one or more features from a claimed combination can, in some cases, beEDGE.272WO -36- Knobbe, Martens, Olson & Bear, LLPexcised from the combination, and the combination may be claimed as a subcombination or variation of a subcombination.

[0120] Moreover, while operations may be depicted in the drawings or described in the specification in a particular order, such operations need not be performed in the particular order shown or in sequential order, or that all operations be performed, to achieve desirable results. Other operations that are not depicted or described can be incorporated in the example methods and processes. For example, one or more additional operations can be performed before, after, simultaneously, or between any of the described operations. Further, the operations may be rearranged or reordered in other implementations. Those skilled in the art will appreciate that in some embodiments, the actual steps taken in the processes illustrated and / or disclosed may differ from those shown in the figures. Depending on the embodiment, certain of the steps described above may be removed, others may be added.

[0121] Furthermore, the features and attributes of the specific embodiments disclosed above may be combined in different ways to form additional embodiments, all of which fall within the scope of the present disclosure. Also, the separation of various system components in the implementations described above should not be understood as requiring such separation in all implementations, and it should be understood that the described components and systems can generally be integrated together in a single product or packaged into multiple products.

[0122] For purposes of this disclosure, certain aspects, advantages, and novel features are described herein. Not necessarily all such advantages may be achieved in accordance with any particular embodiment. Thus, for example, those skilled in the art will recognize that the disclosure may be embodied or carried out in a manner that achieves one advantage or a group of advantages as taught herein without necessarily achieving other advantages as may be taught or suggested herein.

[0123] Language of degree used herein, such as the terms “approximately,” “about,” “generally,” and “substantially” as used herein represent a value, amount, or characteristic close to the stated value, amount, or characteristic that still performs a desired function or achieves a desired result. For example, the terms “approximately”, “about”, “generally,” and “substantially” may refer to an amount that is within less than 10% of, within less than 5% of, within less than 1% of, within less than 0.1% of, and within less than 0.01%EDGE.272WO -37- Knobbe, Martens, Olson & Bear, LLPof the stated amount. As another example, in certain embodiments, the terms “generally parallel” and “substantially parallel” refer to a value, amount, or characteristic that departs from exactly parallel by less than or equal to 15 degrees, 10 degrees, 5 degrees, 3 degrees, 1 degree, 0.1 degree, or otherwise.

[0124] The scope of the present disclosure is not intended to be limited by the specific disclosures of preferred embodiments in this section or elsewhere in this specification, and may be defined by claims as presented in this section or elsewhere in this specification or as presented in the future. The language of the claims is to be interpreted broadly based on the language employed in the claims and not limited to the examples described in the present specification or during the prosecution of the application, which examples are to be construed as non-exclusive.

[0125] Unless the context clearly requires otherwise, throughout the description and the claims, the words “comprise”, “comprising”, and the like, are to be construed in an inclusive sense as opposed to an exclusive or exhaustive sense, that is to say, in the sense of “including, but not limited to”.

[0126] Reference to any prior art in this description is not, and should not be taken as, an acknowledgement or any form of suggestion that that prior art forms part of the common general knowledge in the field of endeavor in any country in the world.

[0127] The inventions may also be said broadly to consist in the parts, elements and features referred to or indicated in the description of the application, individually or collectively, in any or all combinations of two or more of said parts, elements or features.

[0128] Where, in the foregoing description, reference has been made to integers or components having known equivalents thereof, those integers are herein incorporated as if individually set forth. In addition, where the term “substantially” or any of its variants have been used as a word of approximation adjacent to a numerical value or range, it is intended to provide sufficient flexibility in the adjacent numerical value or range that encompasses standard manufacturing tolerances and / or rounding to the next significant figure, whichever is greater.

[0129] It should be noted that various changes and modifications to the presently preferred embodiments described herein will be apparent to those skilled in the art. Such changes and modifications may be made without departing from the spirit and scope of theEDGE.272WO -38- Knobbe, Martens, Olson & Bear, LLPinvention and without diminishing its attendant advantages. For instance, various components may be repositioned as desired. It is therefore intended that such changes and modifications be included within the scope of the invention. Moreover, not all of the features, aspects and advantages are necessarily required to practice the present invention. Accordingly, the scope of the present invention is intended to be defined only by the claims.EDGE.272WO -39- Knobbe, Martens, Olson & Bear, LLP

Claims

WHAT TS CLAIMED IS:

1. A skin treatment system comprising:a console comprising a first station and at least a second station, wherein each of the first station and second station is configured to receive a container;a first conduit placing a container secured to the first station in fluid communication with a handpiece;a second conduit placing a container secured to the second station in fluid communication with the handpiece; anda selector configured to permit a user to choose: (1) whether fluid from a container secured to the first station is permitted to be transferred to the first conduit, and (2) whether fluid from a container secured to the second station is permitted to be transferred to the second conduit;wherein fluid being transferred through the first conduit is fluidly isolated from (e,g„ does not contact) fluid being transferred through the second conduit until such fluids reach the handpiece.

2. The system of Claim 1,wherein the console further comprises a third station, wherein the third station is configured to receive a container;the system further comprising a third conduit placing a container secured to the third station in fluid communication with the handpiece;wherein the selector is configured to permit a user to further choose whether fluid from a container secured to the third station is permitted to be transferred to the third conduit; andwherein fluid being transferred through each of the first conduit, second conduit and third conduit is fluidly isolated from (e.g.. does not contact) fluid being transferred through other conduits until such fluids reach the handpiece.

3. A skin treatment system comprising:a first station and at least a second station, wherein the first station and second station are at least partially on or within a housing;a first conduit placing a container secured to the first station in fluid communication with a handpiece;EDGE.272WO -40- Knobbe, Martens, Olson & Bear, LLPa second conduit placing a container secured to the second station in fluid communication with the handpiece; anda selector configured to permit a user to regulate a transfer of fluid from a first container secured to the first station and transfer of fluid from a second container secured to the second station a container to the handpiece via the first conduit and the second conduit, respectively;wherein fluid being transferred through the first conduit is fluidly isolated from fluid being transferred through the second conduit until such fluids reach the handpiece.

4. A system according to any one of Claims 1 to 3, wherein the system is further configured to fluidly couple the handpiece to a vacuum source.

5. The system of Claim 4, wherein the system comprises a vacuum source.

6. The system of Claim 5, wherein, when activated, the vacuum source is configured to assist with the transfer of fluid from containers secured to the first station and / or the second station.

7. A system according to any one of the preceding claims, wherein the selector comprises a manual selector.

8. The system of Claim 7, wherein the manual selector comprises a rotatable member that is configured to be moved between one of a plurality of distinct positions.

9. A system according to any one of Claims 1 to 6, wherein the selector comprises an electronic selector.

10. The system of Claim 9, wherein the electronic selector comprises at least one of a button, a switch, a touchscreen or any other controller.

11. A system according to any one of the preceding claims, wherein the selector is included with the handpiece, positioned at least partially in and / or on the handpiece and / or positioned at least partially in and / or or a component that is configured to secure to the handpiece.

12. The system of Claim 11, wherein the component is configured to be secured to the handpiece, and wherein the component is configured to be in fluid communication with at least one fluid passage of the handpiece when the component is secured to the handpiece.

13. The system of Claim 12, wherein the component comprises a cartridge that is configured to be secured within a recess, an opening or other portion of the handpiece.EDGE.272WO -41- Knobbe, Martens, Olson & Bear, LLP14. A system according to any one of Claims 11 to 13, wherein the component is coupled to the first conduit and the second conduit.

15. A system according to any one of Claims 11 to 14, wherein the component is disposable.

16. A system according to any one of Claims 1 to 10, wherein the selector is not included with the handpiece, is not positioned at least partially in and / or on the handpiece and is not positioned at least partially in and / or or a component that is configured to secure to the handpiece.

17. The system of Claim 16, wherein the selector is positioned on the console.

18. The system of Claim 16, wherein the selector is positioned on a device or component that is separate of the system.

19. A system according to any one of the preceding claims, wherein the selector is configured to be controlled via audible commands.

20. A system according to any one of the preceding claims, wherein the selector is configured to be controlled via gesture control.

21. A system according to any one of the preceding claims, wherein the first conduit and the second conduit are physically separate and distinct from one another.

22. A system according to any one of Claims 1 to 20, wherein the first conduit and the second conduit are at least partially coupled or secured to one another.

23. A system according to any one of Claims 1 to 20, wherein the first conduit and the second conduit are included in a single conduit having first and second lumens.

24. A system according to any one of the preceding claims, wherein fluid from a container secured to the first station is delivered to the handpiece sequentially relative to fluid from a container secured to the second station.

25. A system according to any one of the preceding claims, wherein fluid from a container secured to the first station is delivered to the handpiece simultaneously relative to fluid from a container secured to the second station.

26. A system according to any one of the preceding claims, wherein the console comprises a removable module, the removable module comprises a fluid outlet that is configured to place a container secured to the first station of the console in fluidEDGE.272WO -42- Knobbe, Martens, Olson & Bear, LLPcommunication with the first conduit and a container secured to the second station of the console in fluid communication with the second conduit.

27. The system of Claim 26, wherein the removable module comprises a plurality of hydraulic components configured to place a container secured to the first station and a container secured to the second station in fluid communication with the fluid outlet, wherein contents of the containers secured to the first and second stations remain fluidly isolated from one another.

28. The system of Claim 27. wherein the plurality of hydraulic components comprises one or more of the following: a valve, a conduit or other fluid passage, a fitting, another fluid control device and / or the like.

29. The system of Claim 28, wherein the valve comprises at least one valve to regulate a flow of fluid through the removable module to the first conduit and / or the second conduit.

30. The system of Claim 29, wherein the at least one valve is configured to be controlled by, at least in part, the selector.

31. A system according to any one of Claims 26 to 30, wherein the fluid outlet comprises a coupling configured to couple the first conduit and the second conduit.

32. The system of Claim 31, wherein the coupling is configured to removably couple to a corresponding coupling that is in fluid communication with the first conduit and the second conduit.

33. A system according to any one of Claims 27 to 32, wherein the removable module outlet comprises a processor, a memory and / or any other electronic components that are configured to regulate at least one of the hydraulic components to control a flow of fluids through the removable module in accordance with a user’s selection of the selector.

34. A system according to any one of the preceding claims, comprising a display configured to identify the station of the console from which fluid from a container secured to said station is being transferred to first or second conduit.

35. The system of Claim 34, wherein the display comprises a display of the console.

36. The system of Claim 35, wherein the display comprises a display device that is separate from the console.EDGE.272WO -43- Knobbe, Martens, Olson & Bear, LLP37. The system of Claim 36, wherein the display is configured to be secured to the console.

38. A system according to any one of the preceding claims, wherein the system comprises the handpiece.

39. A system according to any one of the preceding claims, wherein the handpiece is provided with the first and second conduits.

40. A system according to any one of the preceding claims, wherein the handpiece is disposable.

41. A system according to any one of the preceding claims, wherein the handpiece comprises a tip along a distal end of the handpiece.

42. The system of Claim 41, wherein the tip is removable relative to at least one component of the handpiece.

43. A system according to any one of the preceding claims, wherein the handpiece is configured to abrade skin tissue when the handpiece contacts and is moved relative to said skin tissue.

44. A system according to any one of the preceding claims, wherein the first station is configured to receive a container having a fluid that is different than a fluid contained in a container secured to the second station.

45. A system according to any one of the preceding claims, further comprising a user interface.

46. The system of Claim 45, wherein the user interface comprises a touchscreen device or component.

47. A method of treating skin, wherein the method comprises using a system according to any one of Claims 1 to 4648. The method of Claim 47. wherein the method comprises treating facial tissue.

49. The method of Claim 47 or 48, wherein the method comprises treating a scalp.

50. A method according to any one of Claims 47 to 49, wherein the method comprises treating skin tissue of a limb and / or a torso.

51. A method of treating skin, the method comprising:receiving a first container in a first station of a console of a skin treatment system, wherein the first container contains a first treatment fluid;EDGE.272WO -44- Knobbe, Martens, Olson & Bear, LLPreceiving a second container in a second station of the console, wherein the second container contains a second treatment fluid;transferring a volume of the first treatment fluid from the first container to a first conduit; andtransferring a volume of the second treatment fluid from the second container to a second conduit;wherein the first conduit and the second conduit are configured to be placed in fluid communication with a handpiece;wherein each of the first conduit and the second conduit comprises a distal end that extends to or near the handpiece; andwherein the first conduit is fluidly isolated from the second conduit such that the first treatment fluid does not contact the second treatment fluid until such fluids reach the handpiece.

52. The method of Claim 51, wherein a flow of fluids through the first conduit and the second conduit is controlled by at least one selector.

53. The method of Claim 52, wherein the at least one selector comprises a manual selector.

54. The method of Claim 52, wherein the at least one selector comprises a manual selector (e.g., an electronic selector).

55. A method according to any one of Claims 52 to 54, wherein the at least one selector is located at or near the handpiece.

56. A method according to any one of Claims 52 to 54, wherein the at least one selector is not located at or near the handpiece.

57. The method of Claim 56, wherein the at least one selector is located on the console.

58. The method of Claim 56, wherein the at least one selector is positioned on a separate device or a separate system.

59. A method according to any of Claims 51 to 58, further comprising providing a vacuum or suction force to a distal end of the handpiece by activating a vacuum or suction source, the vacuum or suction source being in fluid communication with the handpiece.EDGE.272WO -45- Knobbe, Martens, Olson & Bear, LLP60. The method of Claim 59, wherein providing a vacuum or suction force helps draw the first treatment fluid from the first container to the first conduit and / or the second treatment fluid from the second container to the second conduit.

61. A method according to any of Claims 51 to 60, wherein a pattern or sequence of transfer of the first treatment fluid to the first conduit and the second treatment fluid to the second conduit is determined manually by a user of the skin treatment system.

62. A method according to any of Claims 51 to 60, wherein a pattern or sequence of transfer of the first treatment fluid to the first conduit and the second treatment fluid to the second conduit is determined at least partially automatically by the skin treatment system.

63. The method of Claim 62, wherein the pattern or sequence of transfer of the first and / or the second fluids depends, at least in part, on a selection by a user of a desired treatment protocol.

64. The method of Claim 63, wherein the selection of the desired treatment protocol is received using a user input device.

65. The method of Claim 64, wherein the user input device is positioned on and / or operatively coupled to the console.

66. The method of Claim 64, wherein the user input device is positioned on and / or operatively coupled to the handpiece and / or a component that is directly or indirectly coupled to the handpiece.

67. A method according to any one of Claims 51 to 66, wherein the handpiece is configured to abrade skin tissue when a distal end of the handpiece contacts and is moved relative to skin tissue.

68. A method according to any one of Claims 51 to 67, wherein the method comprises abrasion of skin tissue.

69. A method according to any one of Claims 51 to 68, wherein the method comprises extraction of impurities and / or other materials (e.g., sebum, blackheads, oil, dirt, etc.) from skin tissue.

70. A method according to any one of Claims 51 to 68, wherein the first treatment fluid is transferred from the first container to the first conduit sequentially relative to a transfer of the second treatment fluid from the second container to the second conduit.EDGE.272WO -46- Knobbe, Martens, Olson & Bear, LLP71. A method according to any one of Claims 51 to 68, wherein the first treatment fluid is transferred from the first container to the first conduit simultaneously relative to a transfer of the second treatment fluid from the second container to the second conduit.

72. A method according to any one of Claims 51 to 71, wherein the method comprises treating facial tissue.

73. A method according to any one of Claims 51 to 72, wherein the method comprises treating a scalp.

74. A method according to any one of Claims 51 to 73, wherein the method comprises treating skin tissue of a limb and / or a torso.EDGE.272WO -47- Knobbe, Martens, Olson & Bear, LLP

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