Methods and compositions for treating an angiotensinogen- (AGT-) associated disorder

ZA202504176BActive Publication Date: 2026-08-26ALNYLAM PHARMACEUTICALS INC
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Patent Information

Application Number
ZA202504176
Authority / Receiving Office
ZA · ZA
Patent Type
Patents
Current Assignee / Owner
Priority Date
2020-04-30
Filing Date
2025-05-16
Publication Date
2026-08-26
Estimated Expiration
2045-05-16
Patent Text Reader

Abstract

The present invention relates to methods of inhibiting the expression of an AGT gene in a subject, as well as methods for treating subjects having an AGT-associated disorder, e.g., hypertension, using RNAi agents, e.g., double stranded RNAi agents, targeting the AGT gene. The invention also relates to methods of decreasing blood pressure levels in a subject using such RNAi agents to inhibit expression of an AGT gene.
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