Herbicide mixture, herbicidal composition, method for controlling undesired vegetation, use, and kit

Abstract

NOT VISIBLE DUE TO STATUS OF PATENT

Description

Herbicide mixtures, herbicidal compositions, methods, uses and kits for controlling undesirable vegetation Technical Field

[0001] The present disclosure relates to a herbicide mixture comprising sulfonepyraclostrobin and isoxazolidinone. The present disclosure also relates to a herbicide composition comprising the herbicide mixture disclosed in the present disclosure and at least one agricultural carrier. The present disclosure discloses a method for preventing and controlling undesirable vegetation, comprising applying a herbicidally effective amount of the herbicide mixture or herbicide composition disclosed in the present disclosure to undesirable vegetation or a place where undesirable vegetation needs to be prevented and controlled. The present disclosure also discloses the use of the herbicide mixture or herbicide composition disclosed in the present disclosure for preventing and controlling undesirable vegetation. The present disclosure also discloses a kit comprising the herbicide mixture or herbicide composition disclosed in the present disclosure. Background Art

[0002] With regard to current crop production, the prevention and control of undesirable vegetation (e.g., weeds) is extremely important. In many cases, although herbicides have an impact on a certain weed spectrum, they do not antagonize other types of weeds that are also present in the crops to be protected. Therefore, there is an urgent need to mix two, three, or more herbicides. In addition, the use of two, three, or more herbicide active ingredients with different modes of action can bring many advantages, such as expanded weed spectrum, reduced application rates, reduced application times, delayed appearance of resistant weed species for selected multiple herbicides, and synergistic effects (wherein efficacy increases) in some cases.

[0003] However, the activity and selectivity of any particular mixture are difficult to predict because the performance of each individual herbicide in the mixture is often affected by the presence of the other herbicide(s), and the activity of the mixture may also vary significantly depending on the chemical identity, plant species, growth stage, environmental conditions, and application rate, among others.

[0004] Kumiai of Japan disclosed Pyroxasulfone in WO2002062770, 3-[(5-difluoromethoxy-1-methyl-3-trifluoromethylpyrazol-4-yl)methylsulfonyl]-4,5-dihydro-5,5-dimethylisoxazole, whose structural formula is The CAS registration number of sulfonepyraclostrobin is 447399-55-5. It is a very long chain fatty acid elongation synthase (VLCFAE) inhibitor. As a herbicide, it can be used in crops such as corn, wheat, and soybeans to control a variety of weeds, such as dayflower, velvetleaf, barnyard grass, wild millet, foxtail grass, ragweed, etc.

[0005] Isoxaflutole is the common name of 5-cyclopropyl-4-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]isoxazole, also known as isoxaflutole, and its structural formula is

[0006] Its CAS registration number is 141112-29-0. Isoxafenone is a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor that can be used in crops such as corn and sugar beets to control broadleaf and annual weeds.

[0007] There is a continuing need in the art for herbicide mixtures, herbicidal compositions, and related methods, uses, and kits for controlling undesirable vegetation. Summary of the Invention

[0008] According to one aspect, the present disclosure provides a herbicide mixture comprising pyraclostrobin and isoxaflutole.

[0009] According to another aspect, the present disclosure relates to a herbicidal composition comprising the herbicide mixture disclosed herein and at least one agriculturally acceptable carrier.

[0010] According to another aspect, the present disclosure provides a method for controlling undesirable vegetation, comprising applying a herbicidally effective amount of the herbicide mixture or herbicidal composition disclosed herein to the undesirable vegetation or to a locus where control of undesirable vegetation is desired.

[0011] According to another aspect, the present disclosure provides use of the herbicide mixture or herbicidal composition disclosed herein for controlling undesirable vegetation.

[0012] According to another aspect, the present disclosure provides a kit comprising the herbicide mixture or herbicidal composition disclosed in the present disclosure.

[0013] More specifically, the present disclosure provides the following solutions:

[0014] 1. A herbicide mixture comprising sulfamethoxazole and isoxaflutole.

[0015] 2. The herbicide mixture of claim 1, wherein the weight ratio of sulfonepyraclostrobin to isoxaflutole is 1.1:1 to 4.9:1.

[0016] 3. The herbicide mixture according to claim 1 or 2, wherein the weight ratio of sulfonepyraclostrobin to isoxaflutole is 1.2:1 to 4.5:1.

[0017] 4. The herbicide mixture according to any one of claims 1 to 3, wherein the weight ratio of sulfonepyraclostrobin to isoxaflutole is 1.3:1 to 4:1.

[0018] 5. The herbicide mixture according to any one of claims 1 to 4, wherein the weight ratio of sulfonepyraclostrobin to isoxaflutole is 1.4:1 to 3:1.

[0019] 6. The herbicide mixture according to any one of claims 1 to 5, wherein the weight ratio of sulfonepyraclostrobin to isoxaflutole is 1.5:1 to 2:1.

[0020] 7. The herbicide mixture according to any one of claims 1 to 6, wherein pyraclostrobin and isoxaflutole are applied jointly or sequentially.

[0021] 8. The herbicide mixture according to any one of claims 1 to 7, wherein the application rate of sulfonepyraclostrobin is 5 to 300 g ai / ha.

[0022] 9. The herbicide mixture according to any one of claims 1 to 8, wherein the application rate of isoxaflutole is 5 to 140 g ai / ha.

[0023] 10. The herbicide mixture of any one of claims 1 to 9, wherein the herbicide mixture is synergistic.

[0024] 11. The herbicide mixture according to any one of claims 1 to 10, wherein the herbicide mixture consists of sulfonepyraclostrobin and isoxaflutole.

[0025] 12. A herbicidal composition comprising the herbicide mixture of any one of claims 1 to 11 and at least one agriculturally acceptable carrier.

[0026] 13. The herbicidal composition according to claim 12, further comprising a surfactant.

[0027] 14. A method for controlling undesirable vegetation, which comprises applying a herbicidally effective amount of the herbicide mixture according to any one of Schemes 1 to 11 or the herbicidal composition according to any one of Schemes 12 to 13 to the undesirable vegetation or a site where undesirable vegetation needs to be controlled.

[0028] 15. The method of claim 14, wherein the undesirable vegetation is controlled in corn.

[0029] 16. The method of claim 14 or 15, wherein the undesirable vegetation is selected from the group consisting of Commelina communis, Abutilon velvetleaf, Echinochloa crusgalli, wild millet, or a combination thereof.

[0030] 17. Use of the herbicide mixture according to any one of claims 1 to 11 or the herbicidal composition according to any one of claims 12 to 13 for controlling undesirable vegetation.

[0031] 18. The use of claim 17, wherein the undesirable vegetation is selected from the group consisting of Commelina communis, Abutilon velvetleaf, Echinochloa crusgalli, wild millet, or a combination thereof.

[0032] 19. A kit comprising the herbicide mixture according to any one of Schemes 1 to 11 or the herbicidal composition according to any one of Schemes 12 to 13. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] Figure 1: ED90 isobologram of the herbicide mixture or herbicide composition of Example 1 against velvetleaf;

[0034] Figure 2 is a graph showing the ED90 isobolites of the herbicide mixture or herbicide composition of Example 2 against wild millet;

[0035] Figure 3: ED90 isobologram of the herbicide mixture or herbicide composition of Example 3 against barnyardgrass;

[0036] Figure 4: ED90 isobologram of the herbicide mixture or herbicide composition of Example 4 against Commelina communis. DETAILED DESCRIPTION

[0037] Before elaborating on the present disclosure in detail, it may be helpful to provide definitions of some terms used in the present disclosure. Unless otherwise specified, all technical and scientific terms used in the present disclosure have the same meaning as commonly understood by ordinary technicians in the field to which the present disclosure belongs.

[0038] As used in this disclosure, the phrase "agriculturally acceptable carrier" refers to carriers that are known and accepted in the art for use in forming a variety of formulations for agricultural or horticultural uses.

[0039] As used in this disclosure, the term "plant" or "crop" includes reference to the plant as a whole, plant organs (e.g., leaves, stems, branches, roots, trunks, twigs, twigs, fruits, etc.), plant cells or plant seeds. This term also includes plant crops, such as fruits. In another embodiment, the term "plant" or "vegetation" may include the propagation material of the plant, which may include all reproductive parts of the plant, such as seeds and vegetative plant materials, such as cuttings and various tubers that can be used for plant propagation. The plant includes seeds, tubers, spores, corms, bulbs, rhizomes, basal sprouts, runners, buds and other parts of the plant, including seedlings and young plants, which are transplanted after germination or after emergence from the soil.

[0040] As used in this disclosure, the term "locus" or "locus where undesirable vegetation needs to be controlled" includes not only places where undesirable vegetation (e.g., weeds) may have grown, but also places where undesirable vegetation (e.g., weeds) has not yet appeared and cultivated areas.

[0041] As used in this disclosure, the term "post-emergence" refers to the application of a herbicide mixture or herbicidal composition to undesirable vegetation (e.g., weeds) as it emerges from the soil, and the term "pre-emergence" refers to the application of a herbicide mixture or herbicidal composition to a locus, weeds, or soil before the undesirable vegetation (e.g., weeds) emerge from the soil.

[0042] As used herein, the term "controlling undesirable vegetation" refers to interfering with the normal growth and development of undesirable vegetation. Various examples of control activity include, but are not limited to, inhibiting root growth, inhibiting shoot growth, inhibiting germination, inhibiting seed production, or reducing the biomass of weeds.

[0043] As used in this disclosure, the term "effective amount" refers to an amount of the compound sufficient to achieve a good level of control when ingested, contacted or perceived. As used in this disclosure, the term "herbicidally effective amount" refers to an amount of active ingredient that produces a herbicidal effect.

[0044] As used in this disclosure, the term "synergistic" means that the effect of the combination of active ingredients is greater than the sum of the effects of each individual ingredient. The term "synergistically effective amount" is an amount that exhibits greater herbicidal activity than the sum of the herbicidal activities of the individual components.

[0045] As used in this disclosure, the term "mixture" or "composition" refers to, but is not limited to, a combination in any physical form, such as a blend, a solution, or an alloy.

[0046] As used in this disclosure, the term "ha" refers to hectares.

[0047] As used in this disclosure, the term "surfactant" refers to an agriculturally acceptable material that provides emulsification, stabilization, spreading, wetting, dispersibility, or other surface-modifying properties.

[0048] Unless expressly stated otherwise, the singular forms "a", "an" and "the" used in this disclosure include both the singular and the plural, and thus, the terms "a", "an" or "at least one" may be used interchangeably in this disclosure.

[0049] Throughout the application, various embodiments are described using the term "comprising (or including)"; however, those skilled in the art will appreciate that, in some specific cases, the embodiments may be described using the language "consisting essentially of" or "consisting of." The term "consisting of" indicates that the mixture or composition preceding the term contains only the components specified in the term and no other components, but may contain impurities, and impurities are only allowed to be present in normal amounts.

[0050] In order to better understand the teachings of the present disclosure, and in no way limit the scope of the teachings, unless otherwise stated, all numerical values, percentages or ratios, reaction conditions, and other numerical values ​​used in the description and scheme of all expressions, as well as for the description and scheme, will be understood to be modified by the term "about" in all cases. Therefore, unless otherwise indicated, the numerical parameters proposed in the following description and scheme are approximate values ​​and can be changed depending on the desired properties to be obtained. At least, each numerical parameter should be interpreted at least according to the numerical value of the reported significant figures and by applying common rounding techniques. In this regard, the use of the term "about" used herein particularly includes ± 10% of the specified numerical value in scope. In addition, the endpoints of all ranges of the same composition or characteristic relating to the present disclosure include the endpoints, can be independently combined, and include all intermediate points and scopes.

[0051] First aspect

[0052] In a first aspect, the present disclosure provides a herbicide mixture comprising pyraclostrobin and isoxazolidinone. It has been found that the herbicide mixture can provide a wider spectrum of weed control than would be expected based on the two herbicides alone, or can reduce the dosage of the individual herbicides, and even achieve a synergistic herbicidal effect in some embodiments.

[0053] In one embodiment of the present disclosure, in the herbicide mixture, pyraclostrobin and isoxaflutole are present in a synergistically herbicidally effective amount.

[0054] In one embodiment of the present disclosure, in the herbicide mixture, the weight ratio of sulfonepyraclostrobin to isoxazolidinone is 1.1:1 to 4.9:1. Within the range of 1.1:1 to 4.9:1, in the herbicide mixture, the weight ratio of sulfonepyraclostrobin to isoxazolidinone can be 1.1:1, 1.2:1, 1.3:1, 1.4:1, 1.5:1, 1.6:1, 1.7:1, 1.8:1, 1.9:1, 2:1, 2.1:1, 2.2:1, 2.3:1, 2.4:1, 2.5:1, 2.6:1, 2.7:1, 2.8:1, 2.9:1, 3:1, 3.1:1, 3.2:1 1, 3.3:1, 3.4:1, 3.5:1, 3.6:1, 3.7:1, 3.8:1, 3.9:1, 4:1, 4.1:1, 4.2:1, 4.3:1, 4.4:1, 4.5:1, 4.6:1, 4.7:1, 4.8:1, 4.9:1, and any weight ratio range with the above two weight ratios as end points, such as 1.2:1 to 4.5:1, 1.3:1 to 4:1, 1.4:1 to 3:1, 1.5:1 to 2:1, etc. In one embodiment of the present disclosure, in the herbicide mixture, the weight ratio of sulfonepyraclostrobin and isoxaflutole may be 1.5:1 to 2:1. In one embodiment of the present disclosure, in the herbicide mixture, the weight ratio of sulfonepyraclostrobin and isoxaflutole may be 1.5:1, 1.75:1 or 2:1.

[0055] In one embodiment of the present disclosure, sulfonepyraclostrobin and isoxaflutole are applied in combination or sequentially. In one example, sulfonepyraclostrobin and isoxaflutole are prepared separately and each is applied as is or diluted to a predetermined concentration for application. In another example, sulfonepyraclostrobin and isoxaflutole are prepared separately and mixed when diluted to a predetermined concentration and then applied. In another example, sulfonepyraclostrobin and isoxaflutole are prepared together and then applied as is or diluted to a predetermined concentration for application.

[0056] The herbicidal effective application rate of the herbicide mixture generally varies with various conditions, such as the type of formulation, weather conditions, crop species, and weed species. In one embodiment of the present disclosure, the application rate of the herbicide mixture can be 10 to 440 grams of active ingredient per hectare (g ai / ha). Within the range of 10 to 440 g ai / ha, the herbicide mixture can be applied at a rate of 10 g ai / ha, 11 g ai / ha, 13 g ai / ha, 15 g ai / ha, 20 g ai / ha, 25 g ai / ha, 30 g ai / ha, 35 g ai / ha, 40 g ai / ha, 45 g ai / ha, 50 g ai / ha, 55 g ai / ha, 60 g ai / ha, 65 g ai / ha, 70 g ai / ha, 75 g ai / ha, 80 g ai / ha, 85 g ai / ha, 90 g ai / ha, 95 g ai / ha, 100 g ai / ha, 110 g ai / ha, 120 g ai / ha, 130 g ai / ha, 140 g ai / ha, 150 g ai / ha, 160 g ai / ha. ai / ha, 170g ai / ha, 180g ai / ha, 190g ai / ha, 200g ai / ha, 210g ai / ha, 220g ai / ha, 230g ai / ha, 240g ai / ha, 250g ai / ha, 260g ai / ha, 270g ai / ha, 280g ai / ha, 290g ai / ha, 300g ai / ha, 310g ai / ha, 320g ai / ha, 330g ai / ha, 340g ai / ha, 350g ai / ha, 360g ai / ha, 370g ai / ha, 380g ai / ha, 390g ai / ha, 400g ai / ha, 410g ai / ha, 420g ai / ha、430g ai / ha, 440 g ai / ha, and any range of application rates based on the above two application rates as endpoints, such as 15 to 400 g ai / ha, 100 to 350 g ai / ha, 15 to 90 g ai / ha, 220 to 330 g ai / ha, 30 to 180 g ai / ha, etc. The application rates of the above herbicide mixtures are based on the total application rate of all active ingredients.

[0057] The herbicidally effective application rate of each active ingredient of the herbicide mixture generally varies with various conditions, such as the type of formulation, weather conditions, crop species, and weed species. In one embodiment of the present disclosure, the application rate of sulfonepyraclostrobin may be 5 to 300 g ai / ha. Within the range of 5 to 300 g ai / ha, the application rate of sulfonepyraclostrobin can be 5 g ai / ha, 6 g ai / ha, 7 g ai / ha, 8 g ai / ha, 9 g ai / ha, 10 g ai / ha, 11 g ai / ha, 12 g ai / ha, 13 g ai / ha, 14 g ai / ha, 15 g ai / ha, 16 g ai / ha, 17 g ai / ha, 18 g ai / ha, 19 g ai / ha, 20 g ai / ha, 21 g ai / ha, 22 g ai / ha, 23 g ai / ha, 24 g ai / ha, 25 g ai / ha, 26 g ai / ha, 27 g ai / ha, 28 g ai / ha, 29 g ai / ha, 30 g ai / ha, 31 g ai / ha, 32 g ai / ha, 33 g ai / ha. ai / ha, 34g ai / ha, 35g ai / ha, 36g ai / ha, 37g ai / ha, 38g ai / ha, 39g ai / ha, 40g ai / ha, 41g ai / ha, 42g ai / ha, 43g ai / ha, 44g ai / ha, 45g ai / ha, 46g ai / ha, 47g ai / ha, 48g ai / ha, 49g ai / ha, 50g ai / ha, 51g ai / ha, 52g ai / ha, 53g ai / ha, 54g ai / ha, 55g ai / ha, 56g ai / ha, 57g ai / ha, 58g ai / ha, 59g ai / ha, 60g ai / ha, 61g ai / ha, 62g ai / ha, 63g ai / ha, 64g ai / ha, 65g ai / ha, 66g ai / ha, 67g ai / ha, 68g ai / ha, 69g ai / ha, 70g ai / ha, 71g ai / ha, 72g ai / ha, 73g ai / ha, 74g ai / ha, 75g ai / ha, 76g ai / ha, 77g ai / ha, 78g ai / ha, 79g ai / ha, 80g ai / ha, 81g ai / ha, 82g ai / ha, 83g ai / ha, 84g ai / ha, 85g ai / ha, 86g ai / ha, 87g ai / ha, 88g ai / ha, 89g ai / ha, 90g ai / ha, 91g ai / ha、92gai / ha, 93g ai / ha, 94g ai / ha, 95g ai / ha, 96g ai / ha, 97g ai / ha, 98g ai / ha, 99g ai / ha, 100g ai / ha, 110g ai / ha, 120g ai / ha, 130g ai / ha, 140g ai / ha, 150g ai / ha, 160g ai / ha, 170g ai / ha, 180g ai / ha, 190g ai / ha, 200g ai / ha, 210gai / ha, 220g ai / ha, 230g ai / ha, 240g ai / ha, 250g ai / ha, 260g ai / ha, 270g ai / ha, 280g ai / ha, 290g ai / ha, 300g ai / ha, and any range of application rates based on the above two application rates as endpoints, such as 8 to 280g ai / ha, 8 to 80g ai / ha, 50 to 250g ai / ha, 100 to 220g ai / ha, 15 to 90g ai / ha, 9 to 60g ai / ha, etc.

[0058] In one type of application method in the public park, the application rate of different grasses can be from 5 to 140gai / ha. Within the range of 5 to 140g ai / ha, the application rate for different plants can be 5g ai / ha, 6g ai / ha, 7g ai / ha, 8g ai / ha, 9g ai / ha, 10g ai / ha, 11g ai / ha, 12g ai / ha, 13g ai / ha, 14g ai / ha, 15g ai / ha, 16g ai / ha, 17g ai / ha, 18g ai / ha, 19g ai / ha, 20g ai / ha, 21g ai / ha, 22g ai / ha, 23g ai / ha, 24g ai / ha, 25g ai / ha, 26g ai / ha, 27g ai / ha, 28g ai / ha, 29g ai / ha, 30g ai / ha, 31g ai / ha, 32g ai / ha, 33g ai / ha, 34g ai / ha, 35g ai / ha, 36g ai / ha, 37g ai / ha, 38g ai / ha, 39g ai / ha, 40g ai / ha, 41g ai / ha, 42g ai / ha, 43g ai / ha, 44g ai / ha, 45g ai / ha, 46g ai / ha, 47g ai / ha, 48g ai / ha, 49g ai / ha, 50g ai / ha, 51g ai / ha, 52g ai / ha, 53g ai / ha, 54g ai / ha, 55g ai / ha, 56g ai / ha, 57g ai / ha, 58g ai / ha, 59g ai / ha, 60g ai / ha, 61g ai / ha, 62g ai / ha, 63g ai / ha, 64g ai / ha, 65g ai / ha, 66g ai / ha, 67g ai / ha, 68g ai / ha, 69g ai / ha, 70g ai / ha, 71g ai / ha, 72g ai / ha, 73g ai / ha, 74g ai / ha, 75g ai / ha, 76g ai / ha, 77g ai / ha, 78g ai / ha, 79g ai / ha, 80g ai / ha, 81g ai / ha, 82g ai / ha, 83g ai / ha, 84g ai / ha, 85g ai / ha, 86g ai / ha, 87g ai / ha, 88g ai / ha, 89g ai / ha, 90g ai / ha, 91g ai / ha, 92g ai / ha, 93g ai / ha, 94g ai / ha, 95g ai / ha, 96g ai / ha, 97g ai / ha, 98gg ai / ha, 5 to 140 g ai / ha, 5 to 36 g ai / ha, 6 to 130 g ai / ha, 20 to 130 g ai / ha, 75 to 125 g ai / ha, 15 to 90 g ai / ha, and the like.

[0059] In some embodiments of the present disclosure, the herbicide mixture is synergistic, that is, the herbicidal active ingredient is more effective when applied in combination than when applied alone. Synergy can be defined as "the interaction of two or more factors such that the effect of the combination is greater than the expected effect of each factor based on the response to individual application" (Shaner, DL, Ed.Herbicide Handbook, 10th ed.Lawrence:Weed Society of America, 2014). In some embodiments, the herbicide mixture exhibits synergy determined using the isobol method by a dose addition model. Determining synergy by the isobol method is described in detail in the Examples section of the present disclosure.

[0060] In one embodiment of the present disclosure, the herbicide mixture may contain other active ingredients, such as other herbicides, insecticides, fungicides, bactericides, nematicides, molluscicides, growth regulators, biological agents, fertilizers, safeners, or mixtures thereof. However, for the avoidance of doubt, it should be understood that such other active ingredients are not necessary for the herbicide mixture of the present invention to achieve the desired control of undesirable vegetation. In further embodiments of the present disclosure, the presence of other active ingredients is premised on not affecting the synergistic effect of the herbicide mixture.

[0061] In one embodiment of the present disclosure, the herbicide mixture does not contain ingredients other than the active ingredient, such as an agriculturally acceptable carrier.

[0062] In one embodiment of the present disclosure, the herbicide mixture consists essentially of pyraclostrobin and isoxaflutole.

[0063] In one embodiment of the present disclosure, the herbicide mixture consists of sulfonepyraclostrobin and isoxaflutole.

[0064] In one embodiment of the present disclosure, the herbicide mixture may be applied pre-emergence.

[0065] Second aspect

[0066] In a second aspect, the present disclosure provides a herbicidal composition comprising the herbicide mixture disclosed in the first aspect of the present disclosure and at least one agriculturally acceptable carrier. It has been found that the herbicidal composition can provide a wider spectrum of weed control than would be expected based on the two separate herbicides, or can reduce the dosage of the separate herbicides, and even achieve a synergistic herbicidal effect in some embodiments.

[0067] In one embodiment of the present disclosure, in the herbicidal composition, pyraclostrobin and isoxaflutole are present in a synergistically herbicidally effective amount.

[0068] In one embodiment of the present disclosure, the herbicidal composition may contain other active ingredients, such as other herbicides, insecticides, fungicides, bactericides, nematicides, molluscicides, growth regulators, biological agents, fertilizers, safeners, or mixtures thereof. However, for the avoidance of doubt, it should be understood that such other active ingredients are not necessary for the herbicidal composition of the present invention to achieve the desired control of undesirable vegetation. In further embodiments of the present disclosure, the presence of other active ingredients is premised on not affecting the synergistic effect of the herbicidal composition.

[0069] In one embodiment of the present disclosure, the active ingredients of the herbicidal composition consist essentially of sulfonepyraclostrobin and isoxaflutole.

[0070] In one embodiment of the present disclosure, the active ingredients of the herbicidal composition consist of sulfonepyraclostrobin and isoxaflutole.

[0071] The agricultural carrier contained in the herbicidal composition of the present disclosure may be a solid carrier or a liquid carrier. Examples of suitable solid carriers include mineral soils such as silica gel, silicates, talc, kaolin, activated clay, limestone, lime, chalk, red basalt, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, sodium carbonate and sodium bicarbonate and sodium sulfate, ground synthetic materials, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, and products of plant origin such as grain flour, bark flour, wood flour and nut shell flour, cellulose powder and other solid carriers. Examples of suitable liquid carriers include water, alcohols such as methanol, cyclohexanol and decanol, ethylene glycol and polypropylene glycol, N,N-dimethylformamide, dimethyl sulfoxide, N-alkylpyrrolidones, aromatic hydrocarbons such as alkylbenzenes and alkylnaphthalenes, paraffin, olive oil, castor oil, linseed oil, tung oil, sesame oil, corn oil, peanut oil, cottonseed oil, soybean oil, rapeseed oil and coconut oil, fatty acid esters, ketones such as cyclohexanone, 2-heptanone, isophorone and 4-hydroxy-4-methyl-2-pentanone, and the like.

[0072] In one embodiment of the present disclosure, the herbicidal composition of the present disclosure may further include a surfactant. Examples of suitable surfactants included in the herbicidal composition of the present disclosure include, but are not limited to, nonionic, anionic, cationic and amphoteric types, such as alkoxylated fatty alcohols, ethoxylated polysorbates (e.g., Tween 20), ethoxylated castor oil, lignin sulfonates, fatty acid sulfonates (e.g., dodecyl sulfonates), phosphates such as phosphates of alcohol alkoxylates, phosphates of alkylphenol alkoxylates and phosphates of styrylphenol ethoxylates, condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or naphthalenesulfonic acid with phenol and formaldehyde, alkylarylsulfonates, ethoxylated alkylphenols and arylphenols, polyalkylene glycols, sorbitol esters, alkali metal (e.g., sodium) lignin sulfonates, tristyrylphenol ethoxylated phosphates, aliphatic alcohol ethoxylates, alkylphenol ethoxylates, ethylene oxide / propylene oxide block copolymers, graft copolymers and polyvinyl alcohol-vinyl acetate copolymers. Other surfactants known in the art may be used as desired.

[0073] The herbicidal compositions of the present disclosure may also contain other ingredients, such as wetting agents, defoaming agents, adhesives, neutralizers, thickeners, binders, chelating agents, stabilizers, buffers or antifreeze agents, to increase the stability, density and viscosity of the composition.

[0074] Without departing from the scope of the present disclosure, the herbicidal compositions of the present disclosure may also be applied together with one or more other herbicides to control a wider variety of undesirable vegetation. When used in conjunction with other herbicides, the compositions may be formulated together with the other herbicides, tank-mixed with the other herbicides, or applied sequentially with the other herbicides. Some of the other herbicides that can be used with the herbicidal compositions of the present disclosure include, but are not limited to, chlorophenoxyacetic acid (4-CPA), chlorophenoxybutyric acid (4-CPB), chlorophenoxypropionic acid (4-CPP), 2,4-D, 2,4-D choline salt, 2,4-D ester and 2,4-D amine, 2,4-DB, 3,4-DA, 3,4-DB, 2,4-DEB, 2,4-DEP, 3,4-DP, 2,3,6-TBA, 2,4,5-T, 2,4,5-TB, acetochlor, acifluorfen, aclofenoxate, clonifen), acrolein, alachlor, allidochlor, alloxydim, allyl alcohol, alorac, amethidione, ametryn, amibuzin, amicarbazone, amidosulfuron, aminocyclopyrachlor, chlor aminopyralid, amiprofos-methyl, amitrole, ammoniumsulfamate, anilofos, anisuron, asulam, atraton, atrazine, azafenidin, azimsulfuron, aziprotryne, barban, Isopropyl m-chlorophenylcarbamate (BCPC), beflubutamid, benazolin, bencarbazone, benfuresate, bensulfuron-methyl, bensulide, benthiocarb, bentazon-sodium, benzadox, benzfendizone, benzipram,Benzobicyclon, benzfendizone, benzofenap, benzofluor, benzoylprop, benzthiazuron, bialaphos, bicyclopyrone, bifenox, bilanafos, bispyribac-sodium, borax, bromacil, bromobonil, bromobutane tide), bromofenoxim, bromoxynil, brompyrazon, butachlor, butafenacil, butenachlor, buthidazole, buthiuron, butroxydim, buturon, butylate, cacodylic acid, cafenstrole, calcium chlorate, calcium cyanamide calciumcyanamide), cambendichlor, carbasulam, carboxazole, chlorprocarb, carfentrazone-ethyl, CDEA, CEPC, chlomethoxyfen, chloramben, chloranocryl, chlorazifop, chlorazine, chlorbromuron, chlorbufam ), chloreturon, chlorfenac, chlorfenprop, chlorflurazole, chlorflurenol, chloridazon, chlorimuron, chlornitrofen, chloropon, chlorotoluron, chloroxuron, chloroxynil, chlorsulfuron, chlorthal,Chlorthiamid, cinidon-ethyl, cinmethylin, cinosulfuron, cisanilide, clethodim, cliodinate, clodinafop-propargyl, clofop, clomazone, clomeprop, cloprop, cloproxydim, clopyralid, cloransulam-methyl, CMA, copper sulfate sulfate), chloramine fork grass (CPMF), chlorpropamine (CPPC), credazine, cresol, cumyluron, cyanatryn, cyanazine, cycloate, cyclopyrimorate, cyclosulfamuron, cycloxydim, cycluron, cyhalofop-butyl, cyperquat, cyprazine, cyprazole, cypromid, daimuron, dalapon, dazomet, delachlor, desmedipham, desmedipham metryn), di-allate, dicamba, dichlobenil, dichloralurea, dichlormate, dichlorprop, dichlorprop-P, diclofop-methyl, diclosulam, diethamquat, diethatyl, difenopenten, difenoxuron, difenzoquat, diflufenzopyr, dimefuron, dimepiperate, dimethachlor, dimethametryn,Dimexano, dimidazon, dinofenate, dinoprop, dinosam, dinoseb, dinoterb, diphenamid, dipropetryn, diquat, disul, diuron, DMPA, DNOC, DSMA, EBEP, eglinazine, endothal, epronaz, EPTC, erbon, esprocarb, ethbenzamide, ethametsulfuron, ethidimuron, ethiolate ), etobenzamid, ethofumesate, ethoxyfen, ethoxysulfuron, etinofen, etnipromid, etobenzanid, EXD, fenasulam, fenoprop, fenoxaprop, fenoxaprop-P-ethyl, fenoxaprop-P-ethyl + isoxadifen-ethyl, fenoxasulfone, fenteracol, fenthiaprop, fentrazamide, fenuron, ferrous sulfate sulfate), flamprop, flamprop-M, flazasulfuron, florasulam, fluazifop, fluazifop-P-butyl, fluazolate, flucarbazone, flucetosulfuron, fluchloralin, flufenacet, flufenican, flufenpyr-ethyl,Flumetsulam, flumezin, flumiclorac-pentyl, flumioxazin, flumipropyn, fluometuron, fluorodifen, fluoroglycofen, fluoromidine, fluoronitrofen, fluothiuron, flupoxam, flupropacil, flupropanate ), flupyrsulfuron, fluridone, flurochloridone, fluroxypyr, fluroxypyr-meptyl, flurtamone, fluthiacet, fomesafen, foramsulfuron, fosamine, fumiclorac, furyloxyfen, glufosinate, glufosinate salts and esters andesters), glufosinate-ammonium, glufosinate-P-ammonium, glyphosate, glyphosate salts and esters, halauxifen, halauxifen-methyl, halosafen, halosulfuron-methyl, haloxydine, haloxyfop-methyl, haloxaline Haloxyfop-P-methyl, hexachloroacetone, hexaflurate, hexazinone, imazamethabenz, imazamox, imazapic, imazapyr, imazaquin, imazosulfuron, imazethapyr, indanofan, indaziflam,Iodobonil, iodomethane, iodosulfuron, iodosulfuron-ethyl-sodium, iofensulfuron, ioxynil, ipazine, ipfencarbazone, iprymidam, isocarbamid, isocil, isomethiozin, isonoruro n), isopolinate, isopropalin, isoproturon, isouron, isoxachlortole, isoxaflutole, isoxapyrifop, karbutilate, ketospiradox, lactofen, lenacil, linuron, methylarsonic acid (MAA), monoammonium methylarsine (MAMA), Esters and amines of MCPA, MCPA-thioethyl, MCPB, mecoprop, mecoprop-P, medinoterb, mefenacet, mefluidide, mesoprazine, mesosulfuron, mesotrione, metam, metamifop, mefenacet-methyl, mesotrione, mesotrione, mefenacet-methyl, mesotrione ... etamitron), metazachlor, metazosulfuron, metflurazon, methabenzthiazuron, methalpropalin, methazole, methiobencarb, methiozolin, methiuron, methometon, methoprotryne, methyl bromide, methyl isothiocyanate, methyldymron, metobenzuron,Metobromuron, metolachlor, metosulam, metoxuron, metribuzin, metsulfuron, metsulfuron-methyl, molinate, monalide, monisouron, monochloroacetic acid acid), monolinuron, monuron, morfamquat, MSMA, naproanilide, napropamide, naptalam, neburon, nicosulfuron, nipyraclofen, nitralin, nitrofen, nitrofluorfen, norflurazon, noruron, octochlor (OCH), ping Orbencarb, ortho-dichlorobenzene, orthosulfamuron, oxadiargyl, oxadiazon, oxapyrazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paraflufen-ethyl, parafluron, paraquat, pebulate, pelargonic acid acid), penoxsulam, pentachlorophenol, pentanochlor, pentoxazone, perfluidone, pethoxamid, phenisopham, phenmedipham, phenmedipham-ethyl, phenobenzuron, phenylmercury acetate, picloram, picolinafen, pinoxaden, piperophos,Potassium arsenite, potassium azide, potassium cyanate, pretilachlor, primisulfuron-methyl, procyazine, prodiamine, profluazol, profluralin, profoxydim, proglinazine, prohexadione-calcium, prometon, prometryn, and natron pronamide, propachlor, propanil, propaquizafop, propazine, propisochlor, propoxycarbazone, propyrisulfuron, propyzamide, prosulfalin, prosulfocarb, prosulfuron, proxan, prynamid chlor), pydanon, pyraclonil, pyraflufen-ethyl, pyrasulfotole, pyrazogyl, pyrazolynate, pyrazosulfuron-ethyl, pyrazoxyfen, pyribenzoxim, pyributicarb, pyriclor, 6-chloro-3-phenyl-4-pyridafol, pyridate, pyriftalid, pyriminobac, pyrimisulfan, pyrithiobac-sodium, pyroxasulfone, pyroxsulam, quinclorac, quinmerac, quinoclamine, quinonamid, quizalofop, quizalofop-P-ethyl,Rhodethanil, rimsulfuron, saflufenacil, S-metolachlor, sebuthylazine, secbumeton, sethoxydim, siduron, simazine, simeton, simetryn, styrene maleic anhydride copolymer (SMA), sodium arsenite, sodium azide, sodium chlorate, sulcotrione, sulfallate, sulfentrazone, sulfometuron, sulfosate, sulfosulfuron, sulfuric acid acid), sulglycapin, swep, SYN-523, trichloroacetic acid (TCA), tebutam, tebuthiuron, tefuryltrione, tembotrione, tepraloxydim, terbacil, terbucarb, terbuchlor, terbumeton, terbuthylazine, terbutryn, tetrafluoron, thiazafluron, thidiazimin, thidiazuron, Thiencarbazone-methyl, thifensulfuron, thifensulfuron-methyl, thiobencarb, tiocarbazil, tioclorim, topramezone, tralkoxydim, triafamone, tri-allate, triasulfuron, triaziflam, tribenuron, tribenuron-methyl, tricamba, triclopyr choline salt,Triclopyr esters and salts, tridiphane, trietazine, trifloxysulfuron, trifluralin, triflusulfuron, trifop, trifopsime, trihydroxytriazine, trimeturon, tripropindan, tritac, tritosulfuron, vernolate, xylachlor, and their salts, esters, optically active isomers, and mixtures.

[0075] The herbicidal compositions of the present disclosure can be prepared or diluted at the time of use. The herbicidal compositions of the present disclosure can also be concentrated compositions or so-called "ready-to-use" compositions, i.e., compositions that are ready for immediate use. Alternatively, the herbicidal compositions of the present disclosure can be applied in a combined spray mixture consisting of separate formulations of the individual active ingredients, for example, in a "tank mix" format.

[0076] The herbicidal compositions of the present disclosure can be used or prepared in any conventional form, for example, a two-pack form, or for example, wettable powders (WP), emulsifiable concentrates (EC), microemulsion concentrates (MEC), water-soluble powders (SP), water-soluble concentrates (SL), suspoemulsions (SE), oil dispersions (OD), emulsion concentrates (BW), for example, oil-in-water and water-in-oil emulsions, sprayable solutions or emulsions, capsule suspensions (CS), suspension concentrates (SC), dusts (DP), oil-miscible solutions (OL), seed dressing products, granules in microgranular form (GR), spray granules, coated granules and absorbent granules, granules for soil application or distribution, water-soluble granules (SG), water-dispersible granules (WDG), ultra-low volume (ULV) formulations, microcapsules or waxes, the individual formulation types being known in the art.

[0077] Such herbicidal compositions can be formulated using agriculturally acceptable carriers, surfactants or other application-promoting adjuvants conventionally used in formulation techniques known in the art.

[0078] In one embodiment of the present disclosure, the total amount of active ingredients in the herbicidal composition can be from about 0.1 to 99 weight percent (wt. %), from about 0.1 to 95 weight percent, or from about 0.1 to 90 weight percent, based on the total weight of the herbicidal composition. In another embodiment, the total amount of active ingredients in the herbicidal composition is from about 20 to 40 weight percent of the total weight of the composition. In another embodiment, the total amount of active ingredients in the composition is from about 0.1%, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5% to about 90%, 93%, 95%, 98%, 99% of the total weight of the composition.

[0079] Aqueous application forms can be prepared from emulsion concentrates, suspensions, pastes, wettable powders, or water-dispersible granules by adding water. To prepare emulsions, pastes, or oil dispersions, the components of the herbicidal composition can be homogenized in water, either as such or dissolved in an oil or solvent, possibly with the aid of a wetting agent, tackifier, dispersant, or emulsifier. Alternatively, concentrates can be prepared comprising the active ingredient, a wetting agent, tackifier, dispersant, or emulsifier, and, if desired, a solvent or oil suitable for dilution with water.

[0080] In the present disclosure, unless otherwise stated, all specific descriptions made in the first aspect are applicable to the second aspect, as if all relevant descriptions have been copied here in the second aspect. Similarly, where appropriate, the description of the composition in the second aspect may also be applicable to the herbicide mixture in the first aspect, as if all relevant descriptions have been copied in the corresponding parts above. For example, unless otherwise stated, all specific descriptions about the weight ratio of herbicide mixture, sulfonepyraclostrobin and isoxazolidinone, the total application rate of sulfonepyraclostrobin and isoxazolidinone, the application rate of each of sulfonepyraclostrobin and isoxazolidinone in the first aspect are applicable to the second aspect, as if all relevant specific descriptions have been copied here in the second aspect. As another example, unless otherwise stated, all specific descriptions about other active ingredients (e.g., other herbicides) in the second aspect are applicable to the first aspect, as if all relevant specific descriptions have been copied in the corresponding parts of the first aspect.

[0081] The third aspect

[0082] In a third aspect, the present disclosure provides a method for controlling unwanted vegetation, comprising applying a herbicidally effective amount of the herbicide mixture described in the first aspect or the herbicidal composition described in the second aspect to plants or a site where unwanted vegetation needs to be controlled.

[0083] In one embodiment of the present disclosure, the undesirable vegetation is controlled in corn.

[0084] In one embodiment of the present disclosure, the undesirable vegetation may be selected from grass weeds and broadleaf weeds. Specifically, the undesirable vegetation may be selected from dayflower, velvetleaf, barnyard grass, wild millet or a combination thereof.

[0085] In one embodiment of the present disclosure, the herbicide mixture or herbicidal composition may be applied pre-emergence.

[0086] The herbicidal mixtures or herbicidal compositions of the present disclosure can be applied to plants or to the locus where control of undesirable vegetation is desired by using conventional ground or aerial dusters, sprayers, and granule applicators, and by other conventional methods known to those skilled in the art.

[0087] In the present disclosure, unless otherwise stated, all the specific descriptions made in the first and second aspects are applicable to the third aspect, as if all relevant descriptions have been copied here in the third aspect. Similarly, where appropriate, the description of the method in the third aspect may also be applicable to the first and second aspects, as if all relevant descriptions are copied in the corresponding parts of the first and second aspects. For example, unless otherwise stated, all the specific descriptions in the first aspect about the herbicide mixture, the weight ratio of sulfonepyraclostrobin and isoxazolidinone, the total application rate of sulfonepyraclostrobin and isoxazolidinone, the application rate of each of sulfonepyraclostrobin and isoxazolidinone, etc. are applicable to the third aspect, as if all relevant specific descriptions have been copied here in the third aspect. For another example, similar to the description of the first aspect of the present disclosure, in one embodiment of the method of the third aspect of the present disclosure, sulfonepyraclostrobin and isoxazolidinone are applied in combination or applied successively. In one example, sulfonepyraclostrobin and isoxazolidinone are prepared separately, and each of them is applied as it is or diluted to a predetermined concentration for application. In another example, sulfonepyraclostrobin and isoxazolidinone are prepared separately, and when diluted to a predetermined concentration, they are mixed and then applied. In another example, sulfonepyraclostrobin and isoxazolidinone are prepared together and then applied as is, or diluted to a predetermined concentration and applied. As another example, unless otherwise stated, all specific descriptions about other active ingredients (e.g., other herbicides) in the second aspect are applicable to the third aspect, as all relevant specific descriptions have been copied to the corresponding parts of the third aspect. As another example, unless otherwise stated, all specific descriptions about undesirable vegetation in the third aspect are applicable to the first aspect and the second aspect, as all relevant specific descriptions have been copied to the corresponding parts of the first aspect and the second aspect.

[0088] The fourth aspect

[0089] In a fourth aspect, the present disclosure provides use of the herbicide mixture or herbicidal composition disclosed herein for controlling undesirable vegetation.

[0090] In one embodiment of the present disclosure, the undesirable vegetation is controlled in corn.

[0091] In one embodiment of the present disclosure, the undesirable vegetation may be selected from grass weeds and broadleaf weeds. Specifically, the undesirable vegetation may be selected from dayflower, velvetleaf, barnyard grass, wild millet or a combination thereof.

[0092] In the present disclosure, unless otherwise stated, all specific descriptions made in the first and second aspects are applicable to the fourth aspect, as if all relevant descriptions have been copied here in the fourth aspect. For example, unless otherwise stated, all specific descriptions about the herbicide mixture, the weight ratio of sulfonepyraclostrobin and isoxazolidinone, the total application rate of sulfonepyraclostrobin and isoxazolidinone, the application rate of each of sulfonepyraclostrobin and isoxazolidinone in the first aspect are applicable to the fourth aspect, as if all relevant specific descriptions have been copied here in the fourth aspect. As another example, unless otherwise stated, all specific descriptions about other active ingredients (e.g., other herbicides) in the second aspect are applicable to the fourth aspect, as if all relevant specific descriptions have been copied to the corresponding parts.

[0093] The fifth aspect

[0094] In a fifth aspect, the present disclosure provides a kit comprising the herbicide mixture or herbicidal composition disclosed in the present disclosure.

[0095] In the present disclosure, unless otherwise stated, all the specific descriptions made in the first and second aspects are applicable to the fifth aspect, as if all relevant descriptions have been copied here in the fifth aspect. Similarly, where appropriate, the description in the fifth aspect may also be applicable to the first and second aspects, as if all relevant descriptions are copied in the corresponding parts of the first and second aspects. For example, unless otherwise stated, all the specific descriptions in the first aspect about the weight ratio of the herbicide mixture, sulfonepyraclostrobin and isoxazolidinone, the total application rate of sulfonepyraclostrobin and isoxazolidinone, the application rate of each of sulfonepyraclostrobin and isoxazolidinone, etc. are applicable to the fifth aspect, as if all relevant specific descriptions have been copied here in the fifth aspect. As another example, unless otherwise stated, all the specific descriptions about other active ingredients (e.g., other herbicides) in the second aspect are applicable to the fifth aspect, as if all relevant specific descriptions have been copied to the corresponding parts.

[0096] In addition to the active ingredients sulfamethoxam and isoxaflutole contained in the herbicide mixture described in the present disclosure, the kit of the present disclosure may also include one or more other active ingredients and / or inactive ingredients, and the active ingredients and the inactive ingredients may be provided in the herbicide mixture or provided independently.

[0097] In one embodiment of the present disclosure, the kit of the present disclosure includes sulfonepyraclostrobin and isoxaflutole, which are contained in the same container and are optionally combined with a carrier.

[0098] In one embodiment of the present disclosure, the kit of the present disclosure includes the herbicide mixture of the present disclosure contained in one container.

[0099] In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicide mixture of the present disclosure, and optionally in combination with a carrier.

[0100] In one embodiment of the present disclosure, the kit of the present disclosure includes the herbicidal composition of the present disclosure contained in a container.

[0101] In one embodiment of the present disclosure, the kit of the present disclosure includes sulfonepyraclostrobin and isoxaflutole, each contained in a separate container, and each optionally combined with a carrier.

[0102] In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicide mixture of the present disclosure, wherein pyraclostrobin and isoxaflutole are each contained in a separate container, and each is optionally combined with a carrier.

[0103] In one embodiment of the present disclosure, the kit of the present disclosure comprises the herbicidal composition of the present disclosure, and pyraclostrobin, isoxaflutole and an agricultural carrier are each contained in a separate container.

[0104] In one embodiment of the present disclosure, the kit of the present disclosure includes the herbicidal composition of the present disclosure, sulfonepyraclostrobin and isoxaflutole are each contained in an independent container, and the agricultural carrier is contained in the container containing sulfonepyraclostrobin or isoxaflutole.

[0105] In one embodiment of the present disclosure, the kit of the present disclosure further comprises instructions on how to apply sulfonepyraclostrobin, isoxaflutole, the herbicide mixture of the present disclosure, or the herbicidal composition of the present disclosure to the location of the undesirable vegetation.

[0106] It will be appreciated that one or more features, aspects or embodiments of the present disclosure may be combined with one or more other features, aspects or embodiments of the present disclosure.

[0107] It will be appreciated that all embodiments of the present disclosure, including those specifically described with respect to different aspects of the present disclosure, can be combined with any other embodiment of the present disclosure, as appropriate.

[0108] Example

[0109] The following embodiments are not intended to limit the present disclosure, but are merely used to illustrate how the present disclosure may be implemented.

[0110] Experimental drug source

[0111] 835 g / L sulfonepyraclostrobin SC was provided by Adama Agam Ltd.;

[0112] 20% isoxathiapiprolin SC was provided by Hefei Xingyu Chemical Co., Ltd.

[0113] Experimental weed source

[0114] The grass seeds used in the experiment are as follows, all provided by the Pesticide Bioassay Center of Shenyang Chemical Research Institute Co., Ltd.:

[0115] Grass weeds: barnyard grass [Echinochloa crus-galli (L.) Beauv], wild millet [Eriochloa villosa (Thunb.) Kunth];

[0116] Broadleaf weeds: velvetleaf (Abutilo theophrasti Medic.), dayflower (Commelina communis L.).

[0117] Example 1: Soil sealing treatment using a mixture of sulfonepyraclostrobin and isoxathiapiprolin to control velvetleaf

[0118] In Example 1, treatment agents 1-5 were prepared according to Table 1 below. Treatment agents 1 and 2 were the experimental agents described above, and treatment agents 3, 4, and 5 were prepared by mixing the experimental agents. The ratios given in treatment agents 3-5 were the ratios of the active ingredients sulfonepyraclostrobin and isoxathiapiprolin. After converting the amount of each treatment agent into the corresponding formulation amount according to the amount of the active ingredient, the agent was diluted with tap water at a water volume of 450 liters / hectare.

[0119] Table 1 Treatment agent preparation

[0120] A fixed amount of velvetleaf was sown in 9 cm high disposable paper cups, covered with 1 cm of soil, pressed down, watered, and placed in a greenhouse for treatment. 24 hours later, the soil was sprayed with a crawler crop sprayer (designed and manufactured by Engineer Research Ltd., UK) at the designed dosage (spray pressure 1.95 kg / cm2, spray volume 450 L / ha, crawler speed 1.48 km / h). The test was repeated four times. After treatment, the test materials were placed in the operation hall. After the liquid was allowed to air dry, they were placed in a greenhouse and managed according to conventional methods. The reaction of weeds to the pesticide was observed and recorded, and the weed control effect of the pesticide on the weeds was regularly visually inspected.

[0121] Thirty days after application, the fresh weight of weeds in each paper cup was investigated and recorded, and the fresh weight inhibition rates of sulfamethoxazole, isoxazolidinone and their combination on velvetleaf were calculated.

[0122] Fresh weight inhibition rate (%) = (control fresh weight - treatment fresh weight) / control fresh weight X 100

[0123] The fresh weight inhibition rate results of Example 1 are shown in Table 2 below:

[0124] Table 2 Inhibition rate of fresh weight of velvetleaf by different treatment agents at different doses

[0125] Then the isobol method was used to evaluate the combined action type of sulfonepyraclostrobin and isoxazolidinone. Professional statistics were performed using DPS software, and the data in Table 2 above were used to determine the dose of sulfonepyraclostrobin and isoxazolidinone that inhibited 90% of the velvetleaf (i.e., ED 90 value), and the ED of sulfonepyraclostrobin and isoxathiapiprolin on velvetleaf at the experimental ratio 90 value.

[0126] The ED of two single doses on velvetleaf is plotted on the graph with the dose of sulfonepyraclostrobin as the horizontal axis and the dose of isoxathiapiprolin as the vertical axis. 90 The coordinate points of the values ​​are connected into a line segment, which is the theoretical equivalent line of the mixture of sulfonepyraclostrobin and isoxathiapiprolin. Then the ED of the mixture of sulfonepyraclostrobin and isoxathiapiprolin on velvetleaf under the experimental proportion is marked on the coordinate graph. 90 If the coordinate point is below the theoretical isoequivalence line, it is a synergistic effect; if it is above the theoretical isoequivalence line, it is an antagonistic effect; if it is close to the theoretical isoequivalence line, it is an additive effect.

[0127] Figure 1 shows the ED of the mixed herbicides sulfonepyraclostrobin and isoxathiapiprolin obtained above on velvetleaf. 90 As can be seen from Figure 1, sulfonepyraclostrobin and isoxaflutole showed synergistic effects at all three ratios tested, namely 3:2, 7:4 and 2:1.

[0128] Example 2: Soil sealing treatment using a mixture of sulfonepyraclostrobin and isoxathiapiprolin to control wild millet

[0129] This Example 2 is basically the same as Example 1, except that the velvetleaf seeds in Example 1 are replaced with wild millet seeds, and Agent 3 is not used.

[0130] The fresh weight inhibition rate results of Example 2 are shown in Table 3 below:

[0131] Table 3 Inhibition rate of fresh weight of wild millet by each treatment agent at different doses

[0132] FIG2 shows the ED of a mixture of sulfonepyraclostrobin and isoxathiapiprolin obtained in Example 1 on wild millet. 90 As can be seen from Figure 2, sulfonepyraclostrobin and isoxaflutole showed synergistic effects at all two ratios tested, namely 7:4 and 2:1.

[0133] Example 3: Soil sealing treatment using a mixture of sulfonepyraclostrobin and isoxathiapiprolinone to control barnyard grass

[0134] This Example 3 is basically the same as Example 1, except that the velvetleaf seeds in Example 1 are replaced with barnyard grass seeds, and agents 3 and 5 are not used.

[0135] The fresh weight inhibition rate results of Example 3 are shown in Table 4 below:

[0136] Table 4 Inhibition rate of fresh weight of barnyard grass by each treatment agent at different doses

[0137] FIG3 shows the ED of a mixture of sulfonepyraclostrobin and isoxathiapiprolin obtained in Example 1 on barnyard grass. 90 As can be seen from Figure 3, at all ratios tested, i.e., 7:4, sulfonepyraclostrobin and isoxazolidinone showed synergistic effects.

[0138] Example 4: Soil sealing treatment using a mixture of sulfonepyraclostrobin and isoxathiapiprolin to control Commelina communis

[0139] This Example 4 is basically the same as Example 1, except that the velvetleaf seeds in Example 1 are replaced with Commelina communis seeds, and Agent 4 is not used.

[0140] The fresh weight inhibition rate results of Example 4 are shown in Table 5 below:

[0141] Table 5 Inhibition rate of fresh weight of Commelina communis under different dosages of each treatment agent

[0142] FIG4 shows the ED of a mixture of sulfonepyraclostrobin and isoxathiapiprolin obtained in Example 1 on Commelina communis. 90 As can be seen from Figure 4, sulfonepyraclostrobin and isoxaflutole showed synergistic effects at all ratios tested, namely 3:2 and 2:1.

[0143] Although the present invention has been shown and described with reference to the preferred embodiments thereof, it will be appreciated by those skilled in the art that many substitutions, modifications and variations may be made thereto without departing from the spirit and scope of the invention. It is therefore intended that all such substitutions, modifications and variations fall within the spirit and broad scope of the appended claims be embraced.

[0144] All publications, patents, and patent applications mentioned in this disclosure are hereby incorporated by reference in their entirety to the same extent as if each individual publication, patent, or patent application was specifically and individually indicated to be incorporated by reference.

[0145] Furthermore, any priority documents of the present disclosure are incorporated herein by reference in their entirety.

Claims

1. A herbicide mixture comprising pyroxasulfone and isoxaflutole.

2. The herbicide mixture according to claim 1, wherein the weight ratio of pyroxasulfone to isoxaflutole is from 1.1:1 to 4.9:

1.

3. The herbicide mixture according to claim 1 or 2, wherein the weight ratio of pyroxasulfone to isoxaflutole is from 1.2:1 to 4.5:

1.

4. The herbicide mixture according to any one of claims 1 - 3, wherein the weight ratio of pyroxasulfone to isoxaflutole is from 1.3:1 to 4:

1.

5. The herbicide mixture according to any one of claims 1 - 4, wherein the weight ratio of pyroxasulfone to isoxaflutole is from 1.4:1 to 3:

1.

6. The herbicide mixture according to any one of claims 1 - 5, wherein the weight ratio of pyroxasulfone to isoxaflutole is from 1.5:1 to 2:

1.

7. The herbicide mixture according to any one of claims 1 - 6, wherein pyroxasulfone and isoxaflutole are applied jointly or sequentially.

8. The herbicide mixture according to any one of claims 1 - 7, wherein the application rate of pyroxasulfone is 5 to 300 g ai / ha.

9. The herbicide mixture according to any one of claims 1 - 8, wherein the application rate of isoxaflutole is 5 to 140 g ai / ha.

10. The herbicide mixture according to any one of claims 1 - 9, wherein the herbicide mixture is synergistic.

11. The herbicide mixture according to any one of claims 1 - 10, wherein the herbicide mixture consists of pyroxasulfone and isoxaflutole.

12. A herbicidal composition comprising the herbicide mixture according to any one of claims 1 - 11 and at least one agricultural carrier.

13. The herbicidal composition according to claim 12, further comprising a surfactant.

14. A method for controlling undesired vegetation, which comprises applying a herbicidally effective amount of the herbicide mixture according to any one of claims 1 - 11 or the herbicidal composition according to any one of claims 12 - 13 to the undesired vegetation or to a site where control of undesired vegetation is required.

15. The method according to claim 14, wherein the undesired vegetation is controlled in maize.

16. The method according to claim 14 or 15, wherein the undesired vegetation is selected from Commelina communis, Abutilon theophrasti, Echinochloa crus - galli, Panicum miliaceum or a combination thereof.

17. Use of the herbicide mixture according to any one of claims 1 - 11 or the herbicidal composition according to any one of claims 12 - 13 for controlling undesired vegetation.

18. The use according to claim 17, wherein the undesired vegetation is selected from Commelina communis, Abutilon theophrasti, Echinochloa crus - galli, Panicum miliaceum or a combination thereof.

19. A kit comprising the herbicide mixture according to any one of claims 1 - 11 or the herbicidal composition according to any one of claims 12 - 13.