https://eureka.patsnap.com/resources/blog/rd-blog/spatial-barcoding-array-chip-patent-landscape-patent-landscape/ · Patsnap · data cut-off 2026-08-31 · downloaded from the live page
Patent Landscape · Genomics & Bioinformatics

Spatial Barcoding Array Chip Patents: Who Leads and Where Filing Is Headed

A data-backed look at spatial barcoding array chip patents: filing trends since 2015, the leading assignees, technology composition by IPC class, and where white space remains for new entrants.

200
Published Records
55%
Top-5 Share of All Records
-54%
Filing Growth 2021→2024
EP
Leading Jurisdiction

Filing growth = 2021 (24 records) → 2024 (11); 2024 is the last year we treat as complete. Top-5 share = the 5 largest assignees ÷ all 200 records in scope (CR5), not the ranked leaders only.

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Published byPatsnap Research··6 min readSourced from Patsnap Eureka
Overview

What the spatial barcoding array chip patent record shows

Spatial barcoding array chips sit at the intersection of molecular biology and microfabrication: substrates, slides or chips carrying positionally encoded barcodes that let sequencing reads be mapped back to a physical location in a tissue section. The 200 records in scope span filings from 2015 through the current data cut-off, covering methods for building the barcoded substrate, the chemistry used to transfer barcodes into biological material, and the downstream analysis of spatially resolved sequencing data. Patent families, not raw document counts, are the fairer unit here because they neutralise aggressive continuation filing and multi-jurisdiction duplication by a single applicant.

Filing activity rose sharply through the back half of the 2010s, peaked in 2020, and has since pulled back — a pattern consistent with a technology that moved from foundational method claims toward consolidation among a smaller set of active filers. Because publication lags filing by roughly 18 months, the most recent two years in the trend understate real filing activity and should not be read as a slowdown on their own.

Filing activity and technology composition, 2015-2026
  1. 1BECTON DICKINSON & CO34
  2. 210X GENOMICS INC22
  3. 3ENCODIA INC22
  4. 4YALE UNIVERSITY18
  5. 5PRESIDENT & FELLOWS OF HARVARD COLLEGE14
  6. 6JOHNS HOPKINS UNIVERSITY11
  7. 7GLYPHIC BIOTECHNOLOGIES INC7
  8. 8DIGITAL BIOLOGY INC7
  9. 9ALIDA BIOSCIENCES INC6
  10. 10CANCER RESEARCH TECHNOLOGY LTD6
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Spatial Barcoding Array Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Data

Filing trend and technology composition

Two views of the same 200-record dataset: filing activity by year, and the IPC subclasses that carry the claims.

Filing trend, 2014-2026

Filings rose from 2 records in 2014 to a peak of 42 in 2020, then declined to 11 by 2024 — a -54% drop from the 24 filings recorded in 2021. Because publication typically lags filing by around 18 months, 2025 and 2026 figures are still incomplete and should not be read as evidence of continued decline.

Filing trend, 2014-202601325385022014201520162017201820194220202021202220232024202532026Most recent year is partial — publication lag means later filings are not yet visible.

Publication lags filing by roughly 18 months, so 2025 onwards are still filling in. Growth rates on this page therefore end at 2024; running them to the last bar would understate the field.

Technology composition by IPC subclass

C12Q (measuring/testing involving enzymes or DNA) appears in 80.0% of the 200 records, making it the dominant claim category, followed by C12N (genetic engineering, 33.0%) and G01N (material analysis, 23.0%). Because a single record can carry several IPC classes, these shares add up to more than 100% and should not be summed.

Technology composition by IPC subclassC12Q · Measuring & testing involving …16080.0%C12N · Microorganisms & genetic engin…6633.0%G01N · Material analysis & testing4623.0%C40B · Combinatorial chemistry librar…3015.0%B01L · Lab apparatus157.5%C12P · Fermentation & enzymatic synth…136.5%C12M · Bioreactors & enzyme apparatus63.0%A61B · Diagnosis & surgery52.5%Other3015.0%

Shares are the percentage of the 200 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Spatial Barcoding Array Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.

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Key Patents

A representative recent filing

Representative Record
US20260071263A12026-03-12

Methods for spatial genomic, epigenomic and multi-omic profiling using transposases and light-activated spatial barcoding

CAMBRIDGE ENTERPRISE LIMITED

The present invention relates to a method of spatially barcoding one or more biological molecules located on or within a substrate by using a transposase complex to label the biological molecule of interest with a detection probe which may then give rise to a spatial barcode. Such analysis may include determining the spatial profiling of one or more biological molecules, specifically the spatial analysis of DNA, open chromatin, chromatin features, proteins and/or RNA which may be spatially barcoded by methods of the invention, either alone or in various combinations. The invention further relates to a transposase complex for use in spatially barcoding one or more biological molecules and reagents for carrying out the method.Abstract text as published; filing date and assignee are shown alongside the record.

US20260071263A1 — patent drawing 1US20260071263A1 — patent drawing 2
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Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Spatial Barcoding Array Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the numbers mean for strategy

Four read-throughs from the concentration, trend and technology-composition data above.

Concentration
55.0% of 200 records
held by the top 5 assignees

The field is led by one dominant filer, not a cluster

A single leader holds 34 records against a fifth-place assignee at 14 — the gap between first and fifth is wide enough that a new entrant is more likely to compete for space below the top ten than to displace the leader outright.

Ranking covers 41 companies total
Filing momentum
-54% (2021→2024)
filings fell from 24 to 11

Peak filing has passed, but the picture is incomplete

Activity peaked at 42 records in 2020 and dropped through to 11 in 2024. Publication lag means 2025-2026 counts will keep rising as records surface, so this should be read as a real cooling from peak rather than a live trend line.

Peak year: 2020 at 42 records
Claim density
80.0% of records
carry a C12Q classification

Core assay claims are heavily occupied

Four in five records touch C12Q (enzyme/DNA measurement and testing), meaning most of the foundational assay-chemistry space already has prior art on file. New filings there face a denser search space than in adjacent apparatus classes.

C12N at 33.0%, G01N at 23.0%
Jurisdiction
55 EPO filings
vs. 40 in the United States

Europe and PCT routes lead US national filings

Europe (55) and WIPO/PCT (52) each carry more filings than the US national route (40), with Australia and Canada each at 12. Freedom-to-operate checks that stop at the US Patent and Trademark Office will miss the larger share of the documented activity.

AT: 7 filings
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Looking for what nobody has claimed yet?

Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to spatial barcoding array chip patent landscape, with the prior art for and against each one.

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Source: Patsnap Eureka. Derived observations on the same dataset. Derived from a Patsnap search on Spatial Barcoding Array Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's Next

Where to take this analysis

The dataset points to three follow-up questions worth running before committing R&D or freedom-to-operate budget.

Map the white space under-claimed branches

B01L (lab apparatus, 7.5%) and A61B (diagnosis/surgery, 2.5%) are thin relative to the core C12Q claims. A targeted search of these subclasses against the leader's portfolio would show whether apparatus-level claims are genuinely open.

Explore white space in Eureka

Track the leader's continuation strategy

With 34 records against a fifth-place count of 14, the top filer's prosecution pattern — continuations, divisionals, PCT-to-national conversions — determines how much of that lead is defensible claim scope versus filing volume.

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Re-check the 2025-2026 trend once lag clears

The apparent -54% drop from 2021 to 2024 is real, but 2025-2026 filings are still being published. Re-running the trend query in 12-18 months will show whether filing has stabilised or continued to soften.

Set a monitoring alert in Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Spatial Barcoding Array Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions about spatial barcoding array chip patents

Answers are grounded in the same dataset. Derived from a Patsnap search on Spatial Barcoding Array Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

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