Activity Regulation TRIZ Cases
- Aptamer-Antibody Enonomers for Drug-Resistant HER2 Cancers
Aptamer-linked antibody enonomers extend serum half-life, disrupt receptor multimers, and target drug-resistant HER2 and ovarian cancer cells.
- smartRNA Oligonucleotides for Reversible mRNA Stabilization
Small artificial RNA raises protein expression by methylating target mRNA polyA tails, delaying deadenylation without genome editing.
- ECMO Anticoagulant Aptamers for Durable Coagulation Control
Direct anticoagulant aptamers inhibit coagulation steps during ECMO to sustain control for hours while reducing bleeding and monitoring burden.
- Plant Regulatory Elements for Precise Gene Expression Control
Modular promoters, introns, leaders, and 3' UTRs enable precise gene expression control in transgenic plants for targeted phenotype modification.