Amide Active Ingredients TRIZ Cases
- RAD51 Modulators for Selective DNA Repair Control
Small molecules selectively increase RAD51 activity in normal cells to repair DNA while sensitizing cancer cells to therapies.
- Carbonic Anhydrase Inhibitors for Mast Cell Regulation
Carbonic anhydrase inhibitors target enzyme activity to suppress type 2 inflammation while minimizing side effects from conventional helminth treatments.
- Pharmacological Modulation of Retinal Signaling Pathways
Administers combined agents targeting Gs, Gq, and Gi pathways to reduce toxic all-trans-retinal accumulation and reactive oxygen species in the retina.
- Tamsulosin Solid Composition Using Low-Solubility Disintegrant
A tamsulosin solid composition uses a low-water-solubility disintegrant dispersed in a matrix former to achieve stable drug release.
- HDAC6 Inhibitor and IMiD Combination for Lymphoma Therapy
Pairing selective HDAC6 inhibitors with immunomodulatory drugs overcomes dose-limiting toxicities while enhancing antitumor efficacy in lymphoma treatment.
- PEA and Silymarin Combination Therapy for Renal Disease Progression
Combining palmitoylethanolamide with silymarin delivers synergistic therapeutic effects for renal diseases.