Bacteria TRIZ Cases
- Fructose-C4-epimerase for stable tagatose production
A heat-resistant polypeptide converts fructose into tagatose via enzymatic epimerization.
- Coprococcus comes Bacteria for Metabolic Syndrome and IBD
Coprococcus comes bacteria activate the aryl hydrocarbon receptor to resolve gut microbiota dysbiosis in metabolic syndrome.
- Microbacterium oleivorans JWG-G2 PET Degradation via Enzymatic Hydrolysis
Microbacterium oleivorans JWG-G2 degrades polyethylene terephthalate via enzymatic hydrolysis, avoiding toxic byproducts from chemical methods.
- Protease-Deficient Filamentous Fungal Cells for Heterologous Protein Production
Removing endogenous proteases from Trichoderma strains prevents protein degradation, boosting antibody yields two-fold over parental lines.
- Marine Microorganism Fermentation Medium for Therapeutic Yield
Optimized salt formulations enhance marine microorganism fermentation to boost therapeutic compound production.
- Mycobacteria Culture Medium with Selective Agents
C-390 and antibiotic inhibitors in the culture medium suppress faster-growing contaminants, enabling reliable isolation of slow-growing mycobacteria.
- Probiotic Composition for Piglet Diarrhea Treatment
Specific probiotic strains prevent antibiotic resistance while reducing diarrhea severity and mortality in swine.
- Casein Enrichment via Heating for Dairy-Free Cheese Substitutes
Heating isolates casein to remove lactose and allergens, creating nutritious dairy-free cheese substitutes.
- Antibiotic-Sensitive Bacillus Strains for Safe Probiotic Feed Additives
Selecting antibiotic-sensitive Bacillus strains ensures probiotic efficacy against E. coli and Clostridium perfringens without promoting antibiotic resistance.
- Bacillus Transaldolase Disruption for Purine Nucleotide Production
Disrupting transaldolase in Bacillus redirects pentose phosphate pathway flux to increase inosine and guanosine yields.
- Chitin Conversion to N-acetylglucosamine and Ethanol
Engineered bacteria convert chitin into N-acetylglucosamine, eliminating harsh chemical waste and high energy consumption.
- Recombinant Bacteria Co-Expressing G6PD and MDH for Organic Acid Production
Recombinant bacteria co-express glucose-6-phosphate dehydrogenase and malate dehydrogenase to boost organic acid titers.
- Corynebacterium glutamicum NCgl1221 Inactivation for L-lysine Flux
Inactivating the endogenous NCgl1221 gene redirects carbon flux toward L-lysine synthesis in engineered Corynebacterium glutamicum strains.
- Thermophilic Lysine Decarboxylase Temperature Control
Temperature-controlled activation of a thermophilic lysine decarboxylase prevents cell growth inhibition during the production phase.
- Recombinant Polypeptide Production Using 2M2P and Romidepsin
Replacing valproic acid with trans-2-methyl 2-pentenoic acid and romidepsin boosts recombinant polypeptide production while reducing cytotoxicity.
- CRISPR-Modified Bee Gut Microbiome Degrades Neonicotinoids
CRISPR-Cpf1 editing modifies bee gut microbiomes to assimilate and degrade neonicotinoid pesticides, reversing population declines caused by pesticide exposure.