Bacteria TRIZ Cases

IGFL1 and IGFL2 Lactobacillus plantarum strains replace antibiotic growth promoters by enhancing weight gain and skeletal development without resistance risks.

Segmenting Akkermansia muciniphila into distinct phylogroups resolves the complexity of strain diversity, enabling targeted gut microbiota modulation.

Novel Pseudomonas strains break down thermoplastic polyurethane urethane bonds to reduce material weight and form micropores.

Glycolipid and alditol compositions promote denitrifying microorganism growth, eliminating secondary pollution from metal salt promoters.

A treatment composition introduces mercury-transformative microbes to convert toxic organomercurial compounds into inert elemental mercury.

Recombinant Bacillus subtilis integrates ferredoxin enzymes to balance intracellular reducing force.

Engineered thiolases condense acyl-ACP and acetyl-ACP to elongate fatty acid chains without synthesizing malonyl-ACP.

Engineered Pseudomonas strains express the gcl operon to metabolize ethylene glycol into polyhydroxyalkanoates.

Optimized fermentation parameters and ethyl acetate extraction isolate nigericin as the primary metabolite, resolving low yield and high production costs.

Large particle ion exchange resins prevent cell deposition on the adsorbent bed, maintaining high histidine purification yield.

Culturing microorganisms with introduced genes in a lipophilic substance stabilizes retinoids, minimizing degradation and simplifying purification.

Engineered Deinococcus radiodurans synthesizes gold nanoparticles to adsorb radioactive iodine from solution.

Engineered microbes replace complex chemical synthesis with a two-step enzymatic pathway using deoxyribose-5-phosphate aldolase and aldo-ketoreductase.

Arginine prevents alpha-galactosidase precipitation in low-salt buffers, enabling cation-exchange chromatography without enzyme loss.

Selected bacterial strains in multi-stage active liquid cultures eliminate inconsistent mushroom fermentation, ensuring uniform flavor profiles.

Downregulating light harvesting proteins via RNA interference resolves the saturation bottleneck, boosting oxygen evolution and fatty acid yields.

Slow cooling crystallization reduces protocatechuic acid contamination in gallic acid production.

Strain CGI314 overcomes insufficient in vivo recolonization by adhering to mucosal membranes via optimized physiological parameters.

A culture medium uses chromogenic substrates to generate distinct color signals for rapid vancomycin-resistant Enterococci identification.

Ammonium sulfate precipitation removes clostripain proteases to prevent collagenase degradation during subsequent chromatography steps.

Isolated hydrogenases from Thermococcus spp. convert carbon monoxide or formate into high-purity hydrogen gas at ambient temperature and pressure.

DKB108 mutant strain overcomes low wild-type productivity limits, enabling stable commercial antibiotic production through optimized fermentation.

Introducing a multifunctional enzyme into prokaryotic microorganisms to produce copolymerized PHA containing 3-hydroxyhexanoic acid units.

Engineered microbes convert carbohydrates to terephthalate, replacing petrochemical oxidation with renewable biological synthesis.