Graded attenuation of icsA and rfb genes balances safety with invasiveness for multivalent protection.
Botulinum toxin injections target trigeminal nerve dermatomes to reduce facial pain and headache severity.
Antigenic composition extracts specific virulence-associated proteins to induce protective immunity against strangles while minimizing side effects.
A 20 kDa peptide-based assay detects canine-specific antibodies to identify Lyme disease in dogs.
Viral vectors express DGC enzymes to produce cyclic di-nucleotides inside host cells, resolving inadequate T-cell responses from aluminum adjuvants.
Immobilize biopharmaceuticals in a dehydrated carbohydrate glass matrix to preserve therapeutic activity.
Intranasal MPLA induces Type I interferons via TLR4, reducing Th2 activity and side effects.
Genetically engineered recombinant bacteria lacking core oligosaccharide biosynthesis genes produce modified lipopolysaccharides with altered structures.
Intravenous oncolytic viral vectors combined with immunosuppressive agents extend viral replication duration and enhance tumor destruction effectiveness.
Triple fusion protein and bacteriophage nanoparticles arrayed with F1, V, and PA antigens elicit robust immune responses.
Bacillus subtilis CU1 probiotic strain modulates immune response by shifting cytokine balance, reducing joint damage without drug side effects.
A multi-actuating trigger anchor delivery system deploys anchors to retract or compress tissues via a spool mechanism.