Carbon-Nitrogen Lyases TRIZ Cases
- Engineered Microorganism Using rGlyP for Aerobic C1 Growth
Modular rGlyP engineering and NADPH balancing enable aerobic growth on formate, methanol, methane, or CO2 for sustainable bioproduction.
- Methane-Fed Microbial Pathways for Multi-Carbon Biofuel Production
Engineered microorganisms convert methane into multi-carbon fuels and chemicals, cutting reliance on petroleum and food-based feedstocks.
- PEGylated Phenylalanine Lyase Mutant for Long-Acting PKU Therapy
Site-specific PEGylation helps phenylalanine lyase retain activity, lower immunogenicity, and sustain plasma exposure for PKU treatment.
- Transgenic Microorganisms for Low-Cost L-Piperazic Acid Biosynthesis
Engineered bacteria use an enzymatic biosynthetic pathway to make enantiopure L-piperazic acid at lower cost and with fewer synthetic steps.
- PAL Variant Composition for Stable Low-Aggregation PKU Therapy
Targeted PAL amino acid substitutions improve catalytic activity, thermal stability, and aggregation resistance for more durable PKU therapy.