Cell Dissociation Methods TRIZ Cases
- Bioactive Renal Cells for Kidney Regeneration
Oxygen-responsive bioactive renal cells reduce fibrosis and inflammation while augmenting kidney function in chronic disease.
- Liver Microtissue Encapsulation for Liver Failure Treatment
Encapsulating three different liver cell phenotypes in a closed microcompartment reduces production complexity and cost.
- Laminated RPE and Vascular Cell Sheet for Retinal Transplantation
A laminated cell sheet combines retinal pigment epithelial cells with a vascular forming layer to support tissue integration.
- CD4+ Treg Cell Identification for Inflammatory Disease Therapy
Identify CD4+ regulatory T cells with specific migratory signatures using flow cytometry and surface markers.
- Chitosan Nanofiber Culture Medium for Viscosity-Free Suspension
Chitosan nanofibers suspend cells without raising viscosity, resolving the trade-off between maintaining cell function and enabling easy medium exchange.
- Microfluidic Device Isolating Extracellular Vesicles for Glaucoma Detection
A microfluidic device isolates extracellular vesicle complexes from ocular humor to enable precise biomarker detection.
- Particle Separation via Magnetic Deflection and Gas Ejection
A separation apparatus deflects labeled particles onto a flow channel wall using magnetic fields while gas pressure ejects the suspension.
- 3D Microtissue Formation from Stem Cell Hepatocytes
Culturing pluripotent stem cell-derived hepatocytes in a non-adhesive environment with extracellular matrix proteins to form stable three-dimensional microtissues.
- PD-1 Knockout TILs for Scalable Manufacturing
Silencing PD-1 in tumor infiltrating lymphocytes resolves sterility and scalability contradictions, enabling commercial expansion.
- CTC Isolation Kit with Stabilizing Agent
A circulating tumor cell isolation kit uses a stabilizing agent in the collection container to maintain specimen integrity.
- Microfluidic Cell Separation via Antibody-Coated Pillars
A microfluidic device uses antibody-coated pillars to separate specific cells from blood samples based on bioaffinity and size differences.
- Microfluidic Cavity for CTC Capture via Advection Mixing
A microfluidic cavity structure captures circulating tumor cells using advection-driven mixing and specific binding components.
- Silica-Based Scaffolds for Uterine Cell Polarization
Silica-based scaffolds support polarized uterine cell growth while eliminating pathogen risks from organic substrates.
- Enzymatic Isolation of Adipose-Derived Stem Cells
Collagenase and divalent cations isolate stem cells from lipoaspirate, extending autologous fat graft longevity from six months to five years.
- Progenitor Cell Differentiation for Insulin Production
Differentiating progenitor cells into functional insulin-producing pancreatic islet cells using defined serum-free media protocols.
- Flexible Culture Bag Cell Dissociation via Bending
Bending a flexible hydrophilic culture bag dissociates adherent cells without protease damage or contamination risks.