Cis-Trans-Isomerases TRIZ Cases
- Bacillus Licheniformis Strain Engineering for Higher Protein Secretion
Native prsA copy insertion with dltA or rghR2 disruption boosts Bacillus licheniformis protein yields for industrial enzymes.
- Mutant Prolyl Isomerase for Higher Glutamate-Derived Amino Acid Yield
A position-95 prolyl isomerase mutation improves biosynthesis efficiency and raises yield of glutamate-derived amino acids.
- Cognate Foldase Co-Expression for Gram-Positive Protein Secretion
Co-expressing a cognate foldase with a heterologous polypeptide improves folding, eases secretion stress, and raises yield in Gram-positive hosts.
- Antibody Fragment Expression With Periplasmic Chaperones
Periplasmic Skp, FkpA, and SurA chaperones improve folding and assembly of antibody fragments with non-natural amino acids in E. coli.
- Antibody Expression Vectors with Chaperones for E. coli Periplasm
This case combines parB plasmid stability with FkpA and Skp chaperones to improve folding and antibody fragment yield in E. coli.
- Recombinant E. coli Linoleic Acid Isomerase for Safe CLA Production
Recombinant E. coli expressing Bifidobacterium linoleic acid isomerase converts linoleic acid into conjugated linoleic acid.
- CyPD Inhibitors for Neonatal Cardiomyopathy Mitochondrial Maturation
Cyclophilin D inhibitors close the mitochondrial permeability transition pore to promote myocyte differentiation in neonates.
- FKBP Transglutaminase Substrate for Controlled Protein Labeling
Recombinant FKBP transglutaminase substrate enables site-specific protein labeling via Q-tag enzymatic conjugation.