DNA Preparation TRIZ Cases
- Extracellular DNA Enrichment by Acidic Anion Exchange Separation
Acidic anion exchange selectively captures extracellular DNA while limiting RNA and vesicle binding, enabling clean sequential fractions.
- Eukaryotic Cell Display Screening for Polypeptide Developability
Surface presentation in eukaryotic cell display predicts polypeptide solubility and non-specific binding for earlier developability screening.
- DNA-PKcs and 53BP1 Inhibitor Composition for HDR Gene Editing
Blocking DNA-PKcs and 53BP1 suppresses NHEJ, boosts HDR knock-in efficiency, and improves cell viability during gene editing.
- Closed DNA Purification Workflow for Rapid RCA Production
Automated RCA DNA production combines protein removal, anion exchange purification, and inline monitoring in a closed workflow for on-site use.
- Charged Particle Coatings for Mild Analyte Elution
Oppositely charged particle coatings capture analytes, then break down to release them under mild conditions without desalting before analysis.
- Chemical Bait Composition for Sequence-Independent Nucleic Acid Capture
A two-part chemical bait captures total nucleic acids on non-silica substrates while reducing non-specific binding and false positives.
- Cleavable Plasmid Backbone for High-Purity Insert Separation
Multiple cleavage sites break the plasmid backbone into small fragments, enabling faster insert purification with higher yield and purity.
- Single-Cell Tagmentation for 3′ End Transcript Library Prep
Tagmentation inserts sequencing primers into barcoded mRNA hybrids, cutting single-cell library prep time and reagent use.