Drug Screening TRIZ Cases
- Microfluidic Electrode Screening for Nerve Conduction Velocity
Segmented electrodes in a microfluidic chip enable multipoint nerve-cluster stimulation and conduction velocity measurement to assess remyelination.
- Cardiomyocyte Spheroid Composition for Low-Arrhythmia Myocardial Repair
High-purity stem cell-derived cardiomyocytes are matured within 30 days to improve myocardial repair while lowering transplant-related arrhythmia risk.
- Acoustofluidic Cell Spheroid Fabrication Using Surface Acoustic Waves
Surface acoustic waves cluster cells at pressure nodes to form uniform 3D spheroids quickly and at scale for high-throughput drug screening.
- Stem Cell-Derived Gastruloid Model for Peri-Implantation Embryo Simulation
Built from human pluripotent stem cells, this gastruloid model reproduces bilaminar disc, amniotic cavity, and primitive streak for early embryo testing.
- Ovarian And Uterine Organoids for Multicellular Fertility Modeling
Stem cell-derived ovarian and uterine organoids recreate multicellular tissue interactions for drug screening and disease mechanism studies in fertility care.
- Multiple Myeloma MicroOrganoSpheres for Rapid Drug Screening
Patient-derived micro-organospheres enable rapid screening of multiple myeloma therapies to identify effective drug combinations within two weeks.
- Stem Cell Cardiomyocyte MEA Screening for Drug Cardiotoxicity
MEA screening with human stem cell-derived cardiomyocytes tracks beat rate, spike amplitude, and field potential duration to improve drug cardiotoxicity assessment.
- Lung Progenitor Cell Generation for Alveolar Replacement Therapy
Specific growth factors generate lung progenitor cells that engraft damaged lungs, enabling alveolar repair and pulmonary disease modeling.
- 3D Endometrium Assembloid Culture for In Vitro Embryo Implantation
A hydrogel-based endometrium assembloid enables in vitro embryo implantation studies and screening of agents that modulate receptivity.
- 3D Silk Fibroin Scaffold for Long-Term Mitochondrial Toxicity Screening
A porous 3D silk fibroin scaffold enables stable stem cell culture for weeks, improving chronic mitochondrial drug toxicity screening.