Epidermal Cells/Skin Cells TRIZ Cases
- In Vitro Mammary-Like Organoid Generation from iPSCs
A two-step protocol generates human mammary-like organoids from induced pluripotent stem cells using suspension sphere culture and mixed gel floating 3D culture.
- Cytocapsular Tube Networks for Directed Cell Transport
Cells generate cytocapsulae and tubular networks in 3D matrices to enable directed transportation pathways.
- Breg Cell Expansion via CD40 Agonist and Cytokines
Ex vivo expansion of human B regulatory cells using CD40 agonists and cytokines overcomes peripheral blood rarity for immune modulation.
- Culture Medium for Hair Follicle Stem Cell Production
A composite culture medium containing BMP inhibitors, fibroblast growth factors, and SHH agonists supports epithelial cell proliferation.
- Artificial Tooth Primordium via Non-Adherent Cell Culture
Non-adherent culture of mesenchymal dental pulp cells creates self-assembling tooth primordia that integrate with jawbone without synthetic scaffolds.
- Annelid Hemoglobin Maintains Stem Cell Undifferentiated State
Extracellular annelid hemoglobin prevents rapid stem cell differentiation and maintains undifferentiated state without immunological reactions.
- mRNA Transfection for CAR-T Cell Therapy
Transient mRNA transfection delivers chimeric antigen receptors to immune cells, avoiding cytokine storms and insertional mutagenesis risks.
- Fish Skin Fermentation Liquid for Tyrosinase Inhibition
Aspergillus fermentation of fish skin produces a liquid that inhibits tyrosinase and angiotensin-converting enzyme activities.
- Mammary Stem Cell Isolation via Antibody Segmentation
Antibody compositions bind specific surface markers to separate non-epithelial cells from mammary epithelial populations.
- Microfabricated Tissue Strip Device for Cardiotoxicity Screening
Flexible posts anchor tissue strips to measure contractile force, resolving throughput limitations in current cardiotoxicity screening platforms.