Fibrinogen TRIZ Cases
- Fc-Fibrin Citrullinated Hybrid Molecule for ACPA B-Cell Elimination
An Fc-linked citrullinated fibrin peptide targets ACPA-positive B cells for immune clearance, aiming to reduce chronic rheumatoid inflammation.
- Umbilical Cord Blood Exosome Isolation for Xeno-Free Cell Culture
Micropore filtration and staged separation recover intact cord blood exosomes and plasma proteins for xeno-free cell culture media.
- FGA Allele-Specific CRISPR Knockout for Amyloid Prevention
A 17-20 nt guide RNA directs CRISPR to disable the mutated FGA allele while preserving the functional copy to prevent amyloid formation.