Library Screening TRIZ Cases
- Aptamer Pool Screening for Broad HCP Detection in Biologics
NGS-selected aptamer pools detect broader residual host cell proteins in recombinant protein preparations without slow polyclonal antibody production.
- Rabbit Antibody Library Engineering for pMHC Binding Diversity
PCR mutation of rabbit kappa C80 removes a thiol constraint, expanding pMHC-binding antibody library diversity and isolation potential.
- TCR Inhibitory Peptides for Blocking pMHC-Driven T Cell Activation
Direct TCR-binding peptides block pMHC interaction to control T cell activation and reduce unwanted immune responses.
- Phage Peptide Library Screening for Precise Antibody Detection
A uniform synthetic phage peptide library with sequencing improves antibody detection accuracy and reveals cross-reactive autoimmune epitopes.
- Recombinant Monoclonal Antibody Libraries from Antigen-Binding B Cells
FACS-selected antigen-binding B cells are turned into recombinant antibody libraries to survey broader repertoires and avoid hybridoma instability.